Clinical Features	CN_CNMF		METHLYATION_CNMF		RPPA_CNMF		RPPA_CHIERARCHICAL		MRNASEQ_CNMF		MRNASEQ_CHIERARCHICAL		MIRSEQ_CNMF		MIRSEQ_CHIERARCHICAL		MIRSEQ_MATURE_CNMF		MIRSEQ_MATURE_CHIERARCHICAL	
	nMutated (%)	nWild-Type	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q
KRAS	11 (6%)	183	0.5653	0.893	0.00384	0.145	0.80638	1	0.21916	0.728	0.00448	0.145	0.00165	0.125	0.00322	0.145	0.00073999	0.0937	0.03717	0.389	0.00019	0.0722
HLA-A	16 (8%)	178	0.25942	0.758	0.094269	0.56	0.22279	0.728	0.01763	0.341	0.00101	0.0959	0.066969	0.498	0.43324	0.85	0.0078899	0.214	0.69164	0.952	0.41941	0.848
FBXW7	19 (10%)	175	0.4963	0.857	0.25925	0.758	0.94591	1	0.97095	1	0.33946	0.804	0.6792	0.952	0.40198	0.827	0.45735	0.85	0.22641	0.728	0.543	0.883
HLA-B	11 (6%)	183	0.51879	0.866	0.16411	0.691	0.68456	0.952	0.32696	0.804	0.23841	0.738	0.092329	0.557	0.0192	0.347	0.13446	0.651	0.01349	0.302	0.04777	0.454
PTEN	15 (8%)	179	0.56602	0.893	0.34252	0.804	0.90512	1	0.59059	0.908	0.02615	0.386	0.22813	0.728	0.43351	0.85	0.19361	0.706	1	1	0.41825	0.848
ARID1A	14 (7%)	180	0.0069099	0.202	0.00423	0.145	0.92634	1	0.1244	0.636	0.16718	0.691	0.00065999	0.0937	0.10202	0.578	0.00444	0.145	0.70136	0.955	0.00457	0.145
MAPK1	9 (5%)	185	0.55155	0.888	0.22696	0.728	0.32196	0.804	0.97484	1	0.090409	0.554	0.054969	0.475	0.18195	0.706	0.082639	0.541	0.02103	0.363	0.02218	0.366
EP300	21 (11%)	173	1	1	0.02643	0.386	0.24692	0.754	0.03792	0.389	0.13538	0.651	0.072199	0.498	0.84015	1	0.0096499	0.24	1	1	0.24989	0.754
PIK3CA	53 (27%)	141	0.03537	0.389	0.28273	0.777	0.43237	0.85	0.29866	0.777	0.34976	0.805	0.00392	0.145	0.33266	0.804	0.34683	0.804	0.48275	0.855	0.23255	0.736
NFE2L2	12 (6%)	182	0.9272	1	0.097869	0.572	0.29862	0.777	0.050129	0.465	0.45767	0.85	0.04651	0.453	0.03616	0.389	0.01795	0.341	0.3861	0.827	0.073419	0.498
FAT2	11 (6%)	183	0.61334	0.911	0.051579	0.467	0.9003	1	0.62261	0.917	0.064569	0.498	0.48209	0.855	0.58284	0.904	0.76175	1	0.070429	0.498	0.089549	0.554
ZNF750	10 (5%)	184	0.085409	0.55	0.36677	0.823	0.89963	1	0.15403	0.691	0.50864	0.866	0.29035	0.777	0.18157	0.706	0.18962	0.706	0.47119	0.854	0.072579	0.498
BAP1	4 (2%)	190	0.14116	0.662	0.058319	0.48	NA	NA	NA	NA	0.51076	0.866	0.4538	0.85	0.68997	0.952	0.35308	0.806	0.25682	0.758	0.17244	0.697
RAB35	4 (2%)	190	0.25938	0.758	0.45394	0.85	NA	NA	NA	NA	0.76874	1	0.45374	0.85	0.47401	0.854	0.10665	0.587	0.29177	0.777	0.03124	0.389
ERBB3	11 (6%)	183	0.072579	0.498	0.12548	0.636	0.91437	1	0.79123	1	0.03241	0.389	0.01011	0.24	0.078399	0.523	0.02905	0.389	0.92954	1	0.33421	0.804
SMAD4	7 (4%)	187	0.48805	0.855	0.34599	0.804	0.57331	0.893	0.92003	1	0.51469	0.866	1	1	0.72254	0.977	0.59938	0.908	1	1	0.94482	1
TCTE1	5 (3%)	189	0.18228	0.706	0.31801	0.804	0.31205	0.801	0.04276	0.428	0.01717	0.341	0.40458	0.827	0.02475	0.386	0.10116	0.578	0.19982	0.706	0.33682	0.804
NHS	12 (6%)	182	0.86154	1	0.97821	1	0.64245	0.939	0.92622	1	0.75944	1	0.27609	0.777	0.9328	1	0.83136	1	0.42438	0.85	0.43389	0.85
LIN9	7 (4%)	187	0.15738	0.691	0.37426	0.825	0.68965	0.952	0.37256	0.825	0.53366	0.883	0.86864	1	0.88758	1	0.2695	0.776	0.29733	0.777	0.89325	1
C12ORF43	4 (2%)	190	0.19877	0.706	0.14545	0.674	NA	NA	NA	NA	0.91166	1	0.45623	0.85	0.47245	0.854	0.20436	0.706	0.29171	0.777	0.1621	0.691
MED1	11 (6%)	183	0.92306	1	0.13335	0.651	0.16929	0.692	0.15552	0.691	0.23502	0.738	0.10345	0.578	0.18659	0.706	0.23885	0.738	0.5068	0.866	0.12186	0.636
USP28	4 (2%)	190	0.1989	0.706	0.54082	0.883	0.32138	0.804	0.90963	1	0.6036	0.908	1	1	0.38936	0.827	0.93775	1	0.20224	0.706	0.82161	1
IDS	7 (4%)	187	0.18946	0.706	0.5343	0.883	0.24791	0.754	0.53682	0.883	1	1	0.87034	1	0.49307	0.856	0.22228	0.728	0.43752	0.85	0.71355	0.968
TRIM9	8 (4%)	186	0.33352	0.804	0.78616	1	0.68748	0.952	0.88026	1	0.090379	0.554	0.66092	0.952	0.54385	0.883	0.03778	0.389	0.56491	0.893	0.35845	0.811
SEMA4B	7 (4%)	187	1	1	0.89147	1	NA	NA	NA	NA	0.36816	0.823	0.86994	1	0.060689	0.48	0.28698	0.777	0.38875	0.827	0.1287	0.643
ARHGAP4	6 (3%)	188	1	1	0.6856	0.952	0.85241	1	0.68577	0.952	0.34619	0.804	1	1	0.50905	0.866	0.22813	0.728	0.69036	0.952	1	1
POU2F1	3 (2%)	191	0.44889	0.85	0.26553	0.77	NA	NA	NA	NA	0.6139	0.911	0.70106	0.955	0.62725	0.92	0.48793	0.855	0.29374	0.777	0.16216	0.691
IFNGR1	6 (3%)	188	1	1	0.74159	0.989	0.60268	0.908	0.9114	1	0.84318	1	1	1	0.32543	0.804	0.03417	0.389	0.053059	0.469	0.78375	1
IGFN1	11 (6%)	183	0.21405	0.728	0.37976	0.825	0.68544	0.952	0.70029	0.955	1	1	0.59292	0.908	0.3541	0.806	0.96636	1	0.33082	0.804	0.84863	1
RPGR	9 (5%)	185	1	1	0.92264	1	0.68762	0.952	0.40429	0.827	0.39296	0.827	0.87855	1	0.91629	1	0.95191	1	0.76112	1	0.8026	1
CASP8	9 (5%)	185	0.67234	0.952	0.4768	0.855	0.51683	0.866	0.1673	0.691	0.21929	0.728	0.46312	0.854	0.56976	0.893	0.44768	0.85	0.12251	0.636	0.43545	0.85
GAS6	4 (2%)	190	0.81573	1	0.11025	0.598	0.45845	0.85	0.28139	0.777	0.7671	1	0.4539	0.85	1	1	0.38928	0.827	0.29236	0.777	0.7559	1
ABCD1	7 (4%)	187	0.60472	0.908	0.92497	1	0.57254	0.893	0.59228	0.908	0.17857	0.706	0.03383	0.389	0.48863	0.855	0.51973	0.866	0.057259	0.48	0.37638	0.825
RPAP1	4 (2%)	190	0.6834	0.952	0.60755	0.909	NA	NA	NA	NA	0.60075	0.908	1	1	1	1	0.74201	0.989	1	1	0.90399	1
HIST1H4E	4 (2%)	190	0.19925	0.706	0.73396	0.988	NA	NA	NA	NA	0.39696	0.827	0.30822	0.797	0.47378	0.854	0.83087	1	0.40068	0.827	0.37964	0.825
NLRC5	7 (4%)	187	0.68117	0.952	0.27367	0.777	0.20348	0.706	0.73556	0.988	0.67966	0.952	0.19566	0.706	0.13821	0.656	0.277	0.777	0.56604	0.893	0.16116	0.691
DDX41	5 (3%)	189	0.02913	0.389	0.11507	0.616	NA	NA	NA	NA	0.56683	0.893	0.40208	0.827	0.33055	0.804	0.77922	1	1	1	0.54584	0.883
MCM7	3 (2%)	191	NA	NA	0.071149	0.498	NA	NA	NA	NA	0.61588	0.911	0.46668	0.854	1	1	0.49054	0.855	0.059819	0.48	0.16291	0.691