Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.0 0.092 0.486 15.0 -9999.0 0.0 15.0 KIRREL 0.006 0.055 -9999.0 0.0 -0.496 5.0 5.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.0 0.092 -9999.0 0.0 -0.487 15.0 15.0 PLCG1 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP 0.002 0.093 -9999.0 0.0 -0.431 14.0 14.0 ChemicalAbstracts:57-88-5 -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP 0.018 0.053 -9999.0 0.0 -0.477 1.0 1.0 FYN 0.005 0.074 -9999.0 0.0 -0.384 14.0 14.0 mol:Ca2+ 0.008 0.082 -9999.0 0.0 -0.427 14.0 14.0 mol:DAG 0.009 0.083 -9999.0 0.0 -0.429 14.0 14.0 NPHS2 -0.002 0.07 -9999.0 0.0 -0.74 4.0 4.0 mol:IP3 0.009 0.083 -9999.0 0.0 -0.429 14.0 14.0 regulation of endocytosis 0.013 0.071 -9999.0 0.0 -0.357 14.0 14.0 Nephrin/NEPH1/podocin/Cholesterol 0.001 0.083 -9999.0 0.0 -0.437 14.0 14.0 establishment of cell polarity -0.0 0.092 -9999.0 0.0 -0.486 15.0 15.0 Nephrin/NEPH1/podocin/NCK1-2 0.017 0.077 -9999.0 0.0 -0.392 14.0 14.0 Nephrin/NEPH1/beta Arrestin2 0.014 0.072 -9999.0 0.0 -0.362 14.0 14.0 NPHS1 -0.006 0.109 -9999.0 0.0 -0.731 10.0 10.0 Nephrin/NEPH1/podocin 0.006 0.075 -9999.0 0.0 -0.387 14.0 14.0 TJP1 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 0.009 0.083 -9999.0 0.0 -0.431 14.0 14.0 CD2AP -0.0 0.075 -9999.0 0.0 -0.436 13.0 13.0 Nephrin/NEPH1/podocin/GRB2 0.009 0.083 -9999.0 0.0 -0.431 14.0 14.0 GRB2 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.006 0.093 -9999.0 0.0 -0.398 16.0 16.0 cytoskeleton organization 0.021 0.067 -9999.0 0.0 -0.635 1.0 1.0 Nephrin/NEPH1 0.002 0.068 -9999.0 0.0 -0.407 11.0 11.0 Nephrin/NEPH1/ZO-1 0.01 0.076 -9999.0 0.0 -0.448 11.0 11.0