Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.059 0.163 0.395 110.0 -9999.0 0.0 110.0 KIRREL -0.032 0.146 -9999.0 0.0 -0.583 40.0 40.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.059 0.163 -9999.0 0.0 -0.396 110.0 110.0 PLCG1 0.01 0.024 -9999.0 0.0 -0.59 1.0 1.0 ARRB2 0.011 0.0 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.011 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.056 0.153 -9999.0 0.0 -0.381 88.0 88.0 ChemicalAbstracts:57-88-5 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.022 0.111 -9999.0 0.0 -0.33 47.0 47.0 FYN -0.041 0.126 -9999.0 0.0 -0.343 67.0 67.0 mol:Ca2+ -0.04 0.133 -9999.0 0.0 -0.367 61.0 61.0 mol:DAG -0.04 0.133 -9999.0 0.0 -0.369 61.0 61.0 NPHS2 -0.02 0.089 -9999.0 0.0 -0.462 23.0 23.0 mol:IP3 -0.04 0.133 -9999.0 0.0 -0.369 61.0 61.0 regulation of endocytosis -0.032 0.12 -9999.0 0.0 -0.324 62.0 62.0 Nephrin/NEPH1/podocin/Cholesterol -0.047 0.132 -9999.0 0.0 -0.37 62.0 62.0 establishment of cell polarity -0.059 0.163 -9999.0 0.0 -0.395 110.0 110.0 Nephrin/NEPH1/podocin/NCK1-2 -0.03 0.125 -9999.0 0.0 -0.479 17.0 17.0 Nephrin/NEPH1/beta Arrestin2 -0.031 0.122 -9999.0 0.0 -0.328 62.0 62.0 NPHS1 -0.057 0.17 -9999.0 0.0 -0.505 76.0 76.0 Nephrin/NEPH1/podocin -0.041 0.127 -9999.0 0.0 -0.344 67.0 67.0 TJP1 0.01 0.024 -9999.0 0.0 -0.59 1.0 1.0 NCK1 0.009 0.034 -9999.0 0.0 -0.59 2.0 2.0 NCK2 0.01 0.024 -9999.0 0.0 -0.59 1.0 1.0 heterophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.04 0.134 -9999.0 0.0 -0.37 61.0 61.0 CD2AP -0.016 0.126 -9999.0 0.0 -0.585 29.0 29.0 Nephrin/NEPH1/podocin/GRB2 -0.039 0.132 -9999.0 0.0 -0.363 62.0 62.0 GRB2 0.011 0.0 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.053 0.15 -9999.0 0.0 -0.386 80.0 80.0 cytoskeleton organization -0.026 0.13 -9999.0 0.0 -0.384 51.0 51.0 Nephrin/NEPH1 -0.04 0.118 -9999.0 0.0 -0.28 110.0 110.0 Nephrin/NEPH1/ZO-1 -0.039 0.135 -9999.0 0.0 -0.375 62.0 62.0