Ras signaling in the CD4+ TCR pathway Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations ERK1-2/ELK1 0.008 0.133 -9999.0 0.0 -0.726 3.0 3.0 MAP3K8 0.007 0.049 -9999.0 0.0 -0.654 1.0 1.0 FOS 0.007 0.12 -9999.0 0.0 -0.76 3.0 3.0 PRKCA 0.0 0.084 -9999.0 0.0 -0.654 3.0 3.0 PTPN7 -0.005 0.098 -9999.0 0.0 -0.588 5.0 5.0 HRAS 0.01 0.001 -9999.0 0.0 -9999.0 0.0 0.0 PRKCB -0.021 0.133 -9999.0 0.0 -0.571 10.0 10.0 NRAS 0.004 0.061 -9999.0 0.0 -0.572 2.0 2.0 RAS family/GTP -0.012 0.056 -9999.0 0.0 -0.374 1.0 1.0 MAPK3 0.006 0.105 -9999.0 0.0 -0.738 3.0 3.0 MAP2K1 0.005 0.103 -9999.0 0.0 -0.443 8.0 8.0 ELK1 0.01 0.005 -9999.0 0.0 -9999.0 0.0 0.0 BRAF -0.026 0.094 -9999.0 0.0 -0.448 8.0 8.0 mol:GTP -0.0 0.001 -9999.0 0.0 -0.006 9.0 9.0 MAPK1 0.006 0.105 -9999.0 0.0 -0.738 3.0 3.0 RAF1 -0.026 0.094 -9999.0 0.0 -0.448 8.0 8.0 KRAS -0.006 0.089 -9999.0 0.0 -0.49 6.0 6.0