Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity -0.002 0.123 0.352 19.0 -9999.0 0.0 19.0 KIRREL 0.006 0.085 -9999.0 0.0 -0.48 5.0 5.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs 0.002 0.124 -9999.0 0.0 -0.353 19.0 19.0 PLCG1 0.023 0.006 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.024 0.004 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.024 0.005 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP 0.029 0.104 -9999.0 0.0 -0.266 18.0 18.0 ChemicalAbstracts:57-88-5 -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.005 0.08 -9999.0 0.0 -0.254 16.0 16.0 FYN -0.018 0.101 0.217 12.0 -0.251 19.0 31.0 mol:Ca2+ 0.028 0.098 -9999.0 0.0 -0.264 16.0 16.0 mol:DAG 0.029 0.099 -9999.0 0.0 -0.265 16.0 16.0 NPHS2 0.01 0.043 -9999.0 0.0 -9999.0 0.0 0.0 mol:IP3 0.029 0.099 -9999.0 0.0 -0.265 16.0 16.0 regulation of endocytosis 0.022 0.094 -9999.0 0.0 -0.24 19.0 19.0 Nephrin/NEPH1/podocin/Cholesterol 0.018 0.1 0.183 1.0 -0.261 19.0 20.0 establishment of cell polarity 0.002 0.123 -9999.0 0.0 -0.352 19.0 19.0 Nephrin/NEPH1/podocin/NCK1-2 0.033 0.102 -9999.0 0.0 -0.246 18.0 18.0 Nephrin/NEPH1/beta Arrestin2 0.024 0.096 -9999.0 0.0 -0.242 19.0 19.0 NPHS1 -0.008 0.142 -9999.0 0.0 -0.48 14.0 14.0 Nephrin/NEPH1/podocin 0.02 0.098 -9999.0 0.0 -0.252 19.0 19.0 TJP1 0.025 0.004 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.022 0.008 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.024 0.006 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 0.03 0.1 -9999.0 0.0 -0.266 16.0 16.0 CD2AP 0.024 0.005 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 0.028 0.106 -9999.0 0.0 -0.266 19.0 19.0 GRB2 0.024 0.005 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.019 0.101 0.223 12.0 -0.242 20.0 32.0 cytoskeleton organization -0.021 0.098 0.196 4.0 -0.311 16.0 20.0 Nephrin/NEPH1 0.006 0.089 -9999.0 0.0 -0.244 19.0 19.0 Nephrin/NEPH1/ZO-1 0.019 0.104 -9999.0 0.0 -0.282 18.0 18.0