Clinical Features	MRNA_CNMF		MRNA_CHIERARCHICAL		MIR_CNMF		MIR_CHIERARCHICAL		CN_CNMF		METHLYATION_CNMF		RPPA_CNMF		RPPA_CHIERARCHICAL		MRNASEQ_CNMF		MRNASEQ_CHIERARCHICAL	
	nMutated (%)	nWild-Type	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q
TP53	79 (28%)	204	0.00072999	0.0154	9.9999e-06	0.00076	0.00134	0.0231	0.15012	0.668	2e-05	0.000844	0.00098999	0.0188	0.03756	0.297	0.0091599	0.0941	0.00208	0.0304	0.0019	0.0304
PIK3R1	32 (11%)	251	0.75211	1	0.1896	0.696	0.19763	0.702	0.5302	1	0.63704	1	0.24555	0.752	0.98787	1	0.67601	1	0.40577	0.956	0.22198	0.74
RB1	24 (8%)	259	0.03555	0.287	0.01754	0.163	0.13384	0.641	0.92286	1	0.10573	0.574	0.01113	0.108	0.48952	1	0.22563	0.743	0.081979	0.487	0.57847	1
PTEN	87 (31%)	196	0.117	0.601	0.075279	0.469	0.02666	0.225	0.63997	1	0.43075	0.98	0.22178	0.74	0.37727	0.917	0.1422	0.655	0.26925	0.783	0.64325	1
NF1	29 (10%)	254	0.080229	0.484	0.00041	0.00916	0.02517	0.217	0.93285	1	0.0085299	0.09	0.068349	0.448	0.23079	0.743	0.0057799	0.0732	0.5667	1	0.4538	1
IDH1	14 (5%)	269	6.9999e-05	0.00205	9.9999e-06	0.00076	3e-05	0.00104	0.00299	0.0406	3e-05	0.00104	2e-05	0.000844	0.00363	0.0476	0.00126	0.0228	0.00079999	0.016	9.9999e-06	0.00076
PIK3CA	29 (10%)	254	0.79106	1	0.16379	0.669	0.57384	1	1	1	0.81622	1	0.82068	1	0.75263	1	0.30974	0.841	0.26224	0.775	0.23653	0.744
STAG2	12 (4%)	271	0.39208	0.934	0.69792	1	0.71537	1	0.59111	1	0.74972	1	0.0434	0.33	0.0069799	0.0758	0.39246	0.934	0.47937	1	0.10334	0.569
SEMG2	11 (4%)	272	0.49997	1	0.42148	0.965	0.55148	1	0.92138	1	0.061559	0.425	0.6191	1	0.22843	0.743	0.44172	0.999	0.81589	1	0.80046	1
MAP3K1	6 (2%)	277	1	1	0.73035	1	0.80844	1	0.64807	1	1	1	NA	NA	NA	NA	NA	NA	0.57051	1	1	1
SLC26A3	7 (2%)	276	0.94094	1	0.76687	1	0.4629	1	0.36308	0.914	0.64928	1	0.18255	0.694	0.16764	0.669	0.15406	0.669	0.1563	0.669	0.1627	0.669
ATRX	16 (6%)	267	0.00207	0.0304	9.9999e-06	0.00076	0.0068499	0.0758	0.01814	0.164	2e-05	0.000844	2e-05	0.000844	0.0064899	0.0747	0.051069	0.366	0.00194	0.0304	0.00023	0.00583
BRAF	6 (2%)	277	0.76703	1	0.71405	1	0.31861	0.859	0.02888	0.239	0.58757	1	NA	NA	1	1	0.64206	1	0.78959	1	1	1
EGFR	74 (26%)	209	0.0064899	0.0747	0.056669	0.399	0.51205	1	0.13793	0.647	9.9999e-06	0.00076	0.00034	0.00807	5e-05	0.00158	0.00018	0.00489	0.04179	0.324	0.0061299	0.0747
TMPRSS6	6 (2%)	277	0.66984	1	0.70078	1	0.66189	1	0.26322	0.775	0.8835	1	0.34764	0.893	0.2557	0.771	0.32758	0.864	0.57389	1	1	1
SEMA3C	11 (4%)	272	0.48152	1	0.17416	0.669	0.12178	0.612	0.84958	1	0.54184	1	0.41291	0.957	0.33836	0.881	0.68433	1	0.10225	0.569	0.16888	0.669
RPL5	7 (2%)	276	0.37897	0.917	0.51023	1	0.86722	1	0.4673	1	1	1	NA	NA	0.84348	1	0.68428	1	0.46608	1	1	1
PDGFRA	12 (4%)	271	0.0205	0.181	0.13476	0.641	0.76184	1	0.093439	0.53	0.1903	0.696	0.73186	1	0.76863	1	0.87456	1	0.050399	0.366	0.01027	0.103
MMP13	5 (2%)	278	0.9109	1	0.22089	0.74	0.76602	1	0.04954	0.366	0.15117	0.668	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA
REN	5 (2%)	278	0.47598	1	0.41729	0.961	0.074709	0.469	0.51128	1	0.61847	1	NA	NA	1	1	0.83723	1	NA	NA	NA	NA
DSP	12 (4%)	271	0.48847	1	0.96308	1	0.56923	1	0.073519	0.469	0.93312	1	0.52932	1	0.65846	1	0.70548	1	NA	NA	NA	NA
CHD8	9 (3%)	274	0.70176	1	0.53199	1	0.13492	0.641	0.64243	1	0.19134	0.696	NA	NA	0.62463	1	0.75943	1	0.27573	0.788	0.61282	1
KDR	8 (3%)	275	0.20163	0.709	0.6547	1	0.28204	0.794	0.5103	1	0.7319	1	0.34472	0.891	0.14478	0.655	0.52709	1	NA	NA	NA	NA
ODF4	3 (1%)	280	0.87913	1	0.35005	0.893	1	1	0.19738	0.702	0.63402	1	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA
TP63	6 (2%)	277	1	1	0.72939	1	0.40751	0.956	0.64446	1	0.77385	1	NA	NA	0.066419	0.443	0.20647	0.72	0.25483	0.771	0.10891	0.575
PRKCD	3 (1%)	280	0.17238	0.669	0.084949	0.497	0.16244	0.669	1	1	0.37625	0.917	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA
ACSM2B	5 (2%)	278	0.079049	0.484	0.27212	0.783	0.59042	1	0.23681	0.744	0.39316	0.934	1	1	NA	NA	NA	NA	0.17427	0.669	1	1
CLCN7	4 (1%)	279	0.11104	0.578	0.77015	1	0.69724	1	0.2593	0.775	0.23549	0.744	0.16758	0.669	NA	NA	NA	NA	NA	NA	NA	NA
DDX5	4 (1%)	279	0.2159	0.739	1	1	0.53828	1	0.44432	0.999	0.14403	0.655	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA
FBN3	11 (4%)	272	0.18924	0.696	0.30571	0.841	0.90436	1	0.92158	1	0.10731	0.574	1	1	0.2793	0.792	0.37474	0.917	0.8543	1	1	1
CD1D	4 (1%)	279	0.87851	1	1	1	0.64485	1	0.12369	0.612	0.82452	1	NA	NA	0.8934	1	1	1	NA	NA	NA	NA
TEX15	8 (3%)	275	0.3097	0.841	0.24215	0.752	0.29983	0.832	0.72162	1	0.55054	1	0.82358	1	0.8685	1	0.27163	0.783	0.00294	0.0406	0.82446	1
KEL	15 (5%)	268	0.54501	1	0.21316	0.736	0.72172	1	0.8881	1	0.091069	0.524	0.1684	0.669	0.37743	0.917	0.91874	1	0.40999	0.956	0.65063	1
MUC17	22 (8%)	261	0.01154	0.11	0.19231	0.696	0.70582	1	0.70165	1	0.9221	1	0.84092	1	0.24434	0.752	0.3264	0.864	0.86142	1	1	1
SLC6A14	5 (2%)	278	0.87954	1	0.48248	1	0.83236	1	1	1	0.82298	1	0.23058	0.743	0.29374	0.821	0.64287	1	NA	NA	NA	NA
LRRC55	6 (2%)	277	0.37403	0.917	0.53649	1	0.33357	0.874	0.87038	1	0.3263	0.864	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA
CD209	5 (2%)	278	0.91244	1	1	1	0.065489	0.443	0.60825	1	0.69199	1	NA	NA	0.49076	1	1	1	NA	NA	NA	NA
LZTR1	11 (4%)	272	1	1	0.51901	1	0.35541	0.9	0.47399	1	0.78812	1	0.12405	0.612	0.66026	1	0.81516	1	0.17362	0.669	0.75123	1