Ras signaling in the CD4+ TCR pathway Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations ERK1-2/ELK1 0.034 0.148 0.289 28.0 -0.379 18.0 46.0 MAP3K8 0.017 0.026 -9999.0 0.0 -0.037 51.0 51.0 FOS 0.028 0.114 0.249 29.0 -0.363 12.0 41.0 PRKCA 0.029 0.032 0.072 6.0 -0.041 78.0 84.0 PTPN7 0.03 0.036 0.086 54.0 -0.046 74.0 128.0 HRAS 0.036 0.011 -9999.0 0.0 -0.001 40.0 40.0 PRKCB 0.001 0.01 0.026 61.0 -0.013 62.0 123.0 NRAS 0.034 0.013 -9999.0 0.0 0.0 66.0 66.0 RAS family/GTP 0.042 0.069 -9999.0 0.0 -0.123 53.0 53.0 MAPK3 0.041 0.063 -9999.0 0.0 -0.333 3.0 3.0 MAP2K1 0.013 0.061 0.185 2.0 -0.216 10.0 12.0 ELK1 0.027 0.033 -9999.0 0.0 -0.049 80.0 80.0 BRAF 0.005 0.027 -9999.0 0.0 -0.208 1.0 1.0 mol:GTP -0.0 0.002 0.004 61.0 -0.003 78.0 139.0 MAPK1 0.017 0.127 -9999.0 0.0 -0.443 28.0 28.0 RAF1 -0.001 0.068 -9999.0 0.0 -0.318 18.0 18.0 KRAS 0.036 0.011 -9999.0 0.0 -0.001 41.0 41.0