Ras signaling in the CD4+ TCR pathway Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations ERK1-2/ELK1 -0.009 0.247 0.325 4.0 -0.746 66.0 70.0 MAP3K8 0.028 0.034 -9999.0 0.0 -0.434 4.0 4.0 FOS -0.013 0.231 0.31 10.0 -0.732 64.0 74.0 PRKCA 0.027 0.018 -9999.0 0.0 -0.318 1.0 1.0 PTPN7 0.003 0.105 -9999.0 0.0 -0.424 45.0 45.0 HRAS 0.029 0.038 -9999.0 0.0 -0.457 5.0 5.0 PRKCB 0.0 0.125 -9999.0 0.0 -0.527 46.0 46.0 NRAS 0.031 0.009 -9999.0 0.0 -9999.0 0.0 0.0 RAS family/GTP 0.053 0.033 -9999.0 0.0 -0.312 3.0 3.0 MAPK3 -0.018 0.218 -9999.0 0.0 -0.766 58.0 58.0 MAP2K1 -0.001 0.155 -9999.0 0.0 -0.618 44.0 44.0 ELK1 0.03 0.015 -9999.0 0.0 -9999.0 0.0 0.0 BRAF -0.003 0.13 -9999.0 0.0 -0.577 39.0 39.0 mol:GTP -0.001 0.002 -9999.0 0.0 -0.005 111.0 111.0 MAPK1 -0.024 0.227 -9999.0 0.0 -0.743 66.0 66.0 RAF1 -0.004 0.132 -9999.0 0.0 -0.568 41.0 41.0 KRAS 0.031 0.008 -9999.0 0.0 -9999.0 0.0 0.0