Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.037 0.146 0.388 12.0 -9999.0 0.0 12.0 KIRREL -0.013 0.127 -9999.0 0.0 -0.68 3.0 3.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.037 0.146 -9999.0 0.0 -0.388 12.0 12.0 PLCG1 0.015 0.052 -9999.0 0.0 -0.468 1.0 1.0 ARRB2 0.021 0.0 -9999.0 0.0 -9999.0 0.0 0.0 WASL -0.016 0.15 -9999.0 0.0 -0.622 5.0 5.0 Nephrin/NEPH1/podocin/CD2AP -0.023 0.137 -9999.0 0.0 -0.371 8.0 8.0 ChemicalAbstracts:57-88-5 -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.02 0.125 -9999.0 0.0 -0.308 8.0 8.0 FYN -0.061 0.168 -9999.0 0.0 -0.353 18.0 18.0 mol:Ca2+ -0.024 0.135 -9999.0 0.0 -0.368 8.0 8.0 mol:DAG -0.024 0.136 -9999.0 0.0 -0.369 8.0 8.0 NPHS2 -0.023 0.13 -9999.0 0.0 -0.496 6.0 6.0 mol:IP3 -0.024 0.136 -9999.0 0.0 -0.369 8.0 8.0 regulation of endocytosis -0.044 0.16 -9999.0 0.0 -0.4 8.0 8.0 Nephrin/NEPH1/podocin/Cholesterol -0.033 0.134 -9999.0 0.0 -0.382 8.0 8.0 establishment of cell polarity -0.037 0.146 -9999.0 0.0 -0.388 12.0 12.0 Nephrin/NEPH1/podocin/NCK1-2 -0.018 0.145 -9999.0 0.0 -0.375 9.0 9.0 Nephrin/NEPH1/beta Arrestin2 -0.043 0.162 -9999.0 0.0 -0.406 8.0 8.0 NPHS1 -0.04 0.155 -9999.0 0.0 -0.492 9.0 9.0 Nephrin/NEPH1/podocin -0.058 0.17 -9999.0 0.0 -0.353 18.0 18.0 TJP1 0.021 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.021 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 -0.003 0.124 -9999.0 0.0 -0.661 3.0 3.0 heterophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.023 0.137 -9999.0 0.0 -0.371 8.0 8.0 CD2AP 0.015 0.052 -9999.0 0.0 -0.468 1.0 1.0 Nephrin/NEPH1/podocin/GRB2 -0.025 0.143 -9999.0 0.0 -0.381 9.0 9.0 GRB2 0.013 0.072 -9999.0 0.0 -0.661 1.0 1.0 homophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.103 0.198 -9999.0 0.0 -0.395 23.0 23.0 cytoskeleton organization -0.02 0.139 -9999.0 0.0 -0.355 8.0 8.0 Nephrin/NEPH1 -0.023 0.105 -9999.0 0.0 -0.333 6.0 6.0 Nephrin/NEPH1/ZO-1 -0.013 0.119 -9999.0 0.0 -0.363 6.0 6.0