Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.395 0.231 0.525 392.0 -9999.0 0.0 392.0 KIRREL -0.06 0.087 -9999.0 0.0 -0.626 9.0 9.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.396 0.232 -9999.0 0.0 -0.526 392.0 392.0 PLCG1 0.029 0.006 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.028 0.032 -9999.0 0.0 -0.707 1.0 1.0 WASL 0.027 0.009 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.415 0.279 -9999.0 0.0 -0.537 411.0 411.0 ChemicalAbstracts:57-88-5 -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.34 0.235 -9999.0 0.0 -0.566 229.0 229.0 FYN -0.399 0.254 0.265 1.0 -0.504 417.0 418.0 mol:Ca2+ -0.407 0.276 -9999.0 0.0 -0.533 403.0 403.0 mol:DAG -0.409 0.278 -9999.0 0.0 -0.538 397.0 397.0 NPHS2 -0.338 0.326 -9999.0 0.0 -0.689 241.0 241.0 mol:IP3 -0.409 0.278 -9999.0 0.0 -0.538 397.0 397.0 regulation of endocytosis -0.371 0.249 -9999.0 0.0 -0.498 369.0 369.0 Nephrin/NEPH1/podocin/Cholesterol -0.421 0.276 -9999.0 0.0 -0.537 417.0 417.0 establishment of cell polarity -0.395 0.231 -9999.0 0.0 -0.525 392.0 392.0 Nephrin/NEPH1/podocin/NCK1-2 -0.378 0.268 -9999.0 0.0 -0.648 215.0 215.0 Nephrin/NEPH1/beta Arrestin2 -0.377 0.254 -9999.0 0.0 -0.506 369.0 369.0 NPHS1 -0.513 0.284 -9999.0 0.0 -0.667 404.0 404.0 Nephrin/NEPH1/podocin -0.397 0.263 -9999.0 0.0 -0.508 417.0 417.0 TJP1 0.03 0.003 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.027 0.03 -9999.0 0.0 -0.635 1.0 1.0 NCK2 0.029 0.006 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.411 0.281 -9999.0 0.0 -0.549 381.0 381.0 CD2AP 0.029 0.006 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 -0.413 0.28 -9999.0 0.0 -0.536 410.0 410.0 GRB2 0.029 0.005 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.391 0.255 0.276 1.0 -0.5 408.0 409.0 cytoskeleton organization -0.43 0.284 -9999.0 0.0 -0.591 350.0 350.0 Nephrin/NEPH1 -0.288 0.173 -9999.0 0.0 -0.384 392.0 392.0 Nephrin/NEPH1/ZO-1 -0.316 0.199 -9999.0 0.0 -0.428 390.0 390.0