Correlation between gene mutation status and molecular subtypes

Brain Lower Grade Glioma (Primary solid tumor)

02 April 2015 | analyses__2015_04_02

Maintainer Information

Citation Information

Maintained by TCGA GDAC Team (Broad Institute/MD Anderson Cancer Center/Harvard Medical School)

Cite as Broad Institute TCGA Genome Data Analysis Center (2015): Correlation between gene mutation status and molecular subtypes. Broad Institute of MIT and Harvard. doi:10.7908/C1XP73ZS

Overview

Introduction

This pipeline computes the correlation between significantly recurrent gene mutations and molecular subtypes.

Summary

Testing the association between mutation status of 146 genes and 12 molecular subtypes across 513 patients, 165 significant findings detected with P value < 0.05 and Q value < 0.25.

IDH1 mutation correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
TP53 mutation correlated to 'MRNA_CHIERARCHICAL', 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
ATRX mutation correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
CIC mutation correlated to 'MRNA_CHIERARCHICAL', 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
NOTCH1 mutation correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
EGFR mutation correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
PIK3R1 mutation correlated to 'CN_CNMF' and 'METHLYATION_CNMF'.
IDH2 mutation correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CNMF'.
NF1 mutation correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
PTEN mutation correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
FUBP1 mutation correlated to 'MRNA_CNMF', 'MRNA_CHIERARCHICAL', 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
PIK3CA mutation correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
NIPBL mutation correlated to 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CNMF'.
CREBZF mutation correlated to 'METHLYATION_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CHIERARCHICAL', and 'MIRSEQ_CHIERARCHICAL'.
SMARCA4 mutation correlated to 'CN_CNMF'.
FAM47C mutation correlated to 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
RBPJ mutation correlated to 'MRNASEQ_CHIERARCHICAL'.
PTPN11 mutation correlated to 'METHLYATION_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
ZMIZ1 mutation correlated to 'MIRSEQ_MATURE_CNMF'.
PDGFRA mutation correlated to 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', and 'MIRSEQ_CHIERARCHICAL'.
PRX mutation correlated to 'MIRSEQ_CHIERARCHICAL'.
WRN mutation correlated to 'MRNASEQ_CHIERARCHICAL'.
PLCG1 mutation correlated to 'CN_CNMF', 'RPPA_CNMF', and 'MRNASEQ_CNMF'.
MYT1 mutation correlated to 'CN_CNMF'.
RIPK4 mutation correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', and 'MIRSEQ_CHIERARCHICAL'.
PTPRH mutation correlated to 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
RBBP6 mutation correlated to 'MRNASEQ_CHIERARCHICAL'.
ZC3H11A mutation correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', and 'MIRSEQ_CHIERARCHICAL'.
TPTE2 mutation correlated to 'CN_CNMF'.
RB1 mutation correlated to 'CN_CNMF', 'METHLYATION_CNMF', and 'MRNASEQ_CNMF'.
MTMR1 mutation correlated to 'MRNASEQ_CHIERARCHICAL'.
CNOT4 mutation correlated to 'MRNASEQ_CHIERARCHICAL'.
ZBTB20 mutation correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', and 'MIRSEQ_CHIERARCHICAL'.
CUL4B mutation correlated to 'MIRSEQ_CHIERARCHICAL'.
PHF3 mutation correlated to 'CN_CNMF'.
AEBP1 mutation correlated to 'MRNASEQ_CHIERARCHICAL'.
SETD2 mutation correlated to 'MRNASEQ_CNMF'.
TPM1 mutation correlated to 'MIRSEQ_MATURE_CNMF'.
MYH8 mutation correlated to 'MRNASEQ_CHIERARCHICAL'.
STAG2 mutation correlated to 'MIRSEQ_CHIERARCHICAL'.
F8 mutation correlated to 'CN_CNMF' and 'METHLYATION_CNMF'.
HOOK1 mutation correlated to 'MRNASEQ_CHIERARCHICAL'.
NR1H3 mutation correlated to 'MIRSEQ_CHIERARCHICAL'.
AGBL1 mutation correlated to 'MIRSEQ_CHIERARCHICAL' and 'MIRSEQ_MATURE_CHIERARCHICAL'.
AMPD1 mutation correlated to 'MRNASEQ_CHIERARCHICAL'.
HLA-DRA mutation correlated to 'CN_CNMF'.
ALPP mutation correlated to 'MRNASEQ_CNMF'.
IGSF8 mutation correlated to 'MRNASEQ_CHIERARCHICAL'.

Results

Overview of the results

Table 1. Get Full Table Overview of the association between mutation status of 146 genes and 12 molecular subtypes. Shown in the table are P values (Q values). Thresholded by P value < 0.05 and Q value < 0.25, 165 significant findings detected.


		Clinical Features	MRNA CNMF	MRNA CHIERARCHICAL	CN CNMF	METHLYATION CNMF	RPPA CNMF	RPPA CHIERARCHICAL	MRNASEQ CNMF	MRNASEQ CHIERARCHICAL	MIRSEQ CNMF	MIRSEQ CHIERARCHICAL	MIRSEQ MATURE CNMF	MIRSEQ MATURE CHIERARCHICAL
	nMutated (%)	nWild-Type	Fisher's exact test	Fisher's exact test	Fisher's exact test	Fisher's exact test	Fisher's exact test	Fisher's exact test	Fisher's exact test	Fisher's exact test	Fisher's exact test	Fisher's exact test	Fisher's exact test	Fisher's exact test
FUBP1	47 (9%)	466	0.0233 (0.248)	0.00689 (0.0998)	1e-05 (0.000319)	1e-05 (0.000319)	0.018 (0.21)	0.804 (1.00)	1e-05 (0.000319)	1e-05 (0.000319)	1e-05 (0.000319)	0.00102 (0.0217)	0.00735 (0.103)	1e-05 (0.000319)
IDH1	398 (78%)	115	0.224 (0.856)	0.883 (1.00)	1e-05 (0.000319)	1e-05 (0.000319)	1e-05 (0.000319)	0.00132 (0.0266)	1e-05 (0.000319)	1e-05 (0.000319)	6e-05 (0.00175)	1e-05 (0.000319)	1e-05 (0.000319)	1e-05 (0.000319)
CIC	108 (21%)	405	0.0503 (0.412)	0.0029 (0.0526)	1e-05 (0.000319)	1e-05 (0.000319)	0.00017 (0.00445)	0.804 (1.00)	1e-05 (0.000319)	1e-05 (0.000319)	1e-05 (0.000319)	1e-05 (0.000319)	1e-05 (0.000319)	1e-05 (0.000319)
PTEN	24 (5%)	489			1e-05 (0.000319)	1e-05 (0.000319)	0.00047 (0.0111)	0.00521 (0.08)	1e-05 (0.000319)	1e-05 (0.000319)	0.00357 (0.0601)	1e-05 (0.000319)	3e-05 (0.000891)	1e-05 (0.000319)
EGFR	35 (7%)	478			1e-05 (0.000319)	1e-05 (0.000319)	0.0299 (0.288)	0.0189 (0.215)	1e-05 (0.000319)	1e-05 (0.000319)	0.0107 (0.139)	1e-05 (0.000319)	1e-05 (0.000319)	1e-05 (0.000319)
TP53	248 (48%)	265	0.0944 (0.571)	0.00597 (0.0894)	1e-05 (0.000319)	1e-05 (0.000319)	0.0316 (0.296)	0.591 (1.00)	1e-05 (0.000319)	1e-05 (0.000319)	1e-05 (0.000319)	2e-05 (0.000626)	0.0527 (0.417)	1e-05 (0.000319)
NOTCH1	42 (8%)	471	0.614 (1.00)	0.279 (0.904)	0.00027 (0.00676)	1e-05 (0.000319)	0.778 (1.00)	0.897 (1.00)	1e-05 (0.000319)	1e-05 (0.000319)	0.0004 (0.0096)	0.00451 (0.0725)	0.00159 (0.031)	0.00011 (0.00301)
ATRX	195 (38%)	318	0.0253 (0.264)	0.119 (0.646)	1e-05 (0.000319)	1e-05 (0.000319)	0.161 (0.778)	0.866 (1.00)	1e-05 (0.000319)	1e-05 (0.000319)	1e-05 (0.000319)	3e-05 (0.000891)	0.257 (0.89)	1e-05 (0.000319)
IDH2	20 (4%)	493			0.00149 (0.0293)	0.00037 (0.009)	0.506 (1.00)	0.18 (0.808)	0.00766 (0.106)	0.00016 (0.00425)	0.0094 (0.126)	0.00076 (0.0169)	0.00291 (0.0526)	0.0463 (0.385)
NF1	33 (6%)	480			0.00124 (0.0253)	1e-05 (0.000319)	0.0533 (0.417)	0.175 (0.799)	1e-05 (0.000319)	1e-05 (0.000319)	0.335 (0.953)	0.00011 (0.00301)	0.00503 (0.078)	1e-05 (0.000319)
PIK3CA	44 (9%)	469			8e-05 (0.00226)	1e-05 (0.000319)	0.686 (1.00)	0.881 (1.00)	0.00107 (0.0223)	3e-05 (0.000891)	0.0097 (0.128)	0.0395 (0.346)	0.332 (0.953)	0.00103 (0.0217)
RIPK4	8 (2%)	505			0.0181 (0.21)	0.00216 (0.0407)	0.343 (0.953)	0.81 (1.00)	0.0075 (0.104)	0.0193 (0.215)	0.3 (0.931)	0.0192 (0.215)	0.504 (1.00)	0.109 (0.623)
ZC3H11A	5 (1%)	508			0.0008 (0.0175)	0.0002 (0.00515)			0.00298 (0.0527)	0.00338 (0.0586)	0.244 (0.878)	0.00722 (0.102)	0.336 (0.953)	0.0679 (0.483)
ZBTB20	21 (4%)	492			0.012 (0.153)	0.00066 (0.015)	0.672 (1.00)	0.516 (1.00)	0.0129 (0.161)	0.0038 (0.0634)	0.159 (0.774)	0.0207 (0.228)	0.0405 (0.348)	0.0326 (0.299)
NIPBL	18 (4%)	495			0.0375 (0.334)	0.00069 (0.0155)	0.523 (1.00)	0.517 (1.00)	0.00394 (0.0651)	0.00489 (0.0772)	0.451 (1.00)	0.173 (0.799)	0.0115 (0.148)	0.0595 (0.442)
CREBZF	7 (1%)	506			0.0515 (0.417)	0.00798 (0.108)	0.0852 (0.527)	0.00499 (0.078)	0.28 (0.904)	0.0224 (0.242)	0.203 (0.849)	0.0136 (0.167)	0.115 (0.637)	0.0532 (0.417)
PTPN11	7 (1%)	506			0.549 (1.00)	0.0177 (0.209)	0.487 (1.00)	0.55 (1.00)	0.0516 (0.417)	0.225 (0.857)	0.222 (0.855)	0.00525 (0.08)	0.0155 (0.188)	0.00257 (0.0474)
PDGFRA	10 (2%)	503			0.321 (0.953)	0.0636 (0.458)	0.473 (1.00)	0.516 (1.00)	0.0067 (0.0986)	0.00012 (0.00323)	0.00066 (0.015)	0.00144 (0.0287)	0.854 (1.00)	0.186 (0.815)
FAM47C	18 (4%)	495			0.309 (0.935)	0.818 (1.00)	0.436 (1.00)	0.287 (0.916)	0.278 (0.904)	0.0118 (0.151)	0.612 (1.00)	0.0923 (0.562)	0.00848 (0.114)	0.00353 (0.06)
PLCG1	6 (1%)	507			0.00458 (0.0729)	0.0273 (0.274)	0.0217 (0.238)	0.433 (1.00)	0.0197 (0.218)	0.374 (0.997)	0.0267 (0.274)	0.0651 (0.467)	0.0537 (0.418)	0.147 (0.745)
PTPRH	8 (2%)	505			0.479 (1.00)	0.444 (1.00)	0.46 (1.00)	0.638 (1.00)	0.0978 (0.581)	0.00202 (0.0385)	0.0579 (0.431)	0.00199 (0.0383)	0.203 (0.851)	0.022 (0.24)
RB1	6 (1%)	507			0.00023 (0.00584)	0.00084 (0.0182)	0.487 (1.00)	0.81 (1.00)	0.0165 (0.196)	0.0959 (0.575)	0.599 (1.00)	0.0327 (0.299)	0.782 (1.00)	0.247 (0.882)
PIK3R1	22 (4%)	491	0.612 (1.00)	0.58 (1.00)	0.019 (0.215)	0.00223 (0.0416)	0.817 (1.00)	0.937 (1.00)	0.124 (0.664)	0.0373 (0.333)	0.0862 (0.532)	0.582 (1.00)	0.962 (1.00)	0.629 (1.00)
F8	9 (2%)	504			0.00438 (0.0711)	0.00531 (0.0802)	0.344 (0.953)	0.81 (1.00)	0.034 (0.307)	0.055 (0.419)	0.174 (0.799)	0.0961 (0.575)	0.342 (0.953)	0.578 (1.00)
AGBL1	5 (1%)	508			0.167 (0.784)	0.116 (0.64)	0.442 (1.00)	0.43 (1.00)	0.031 (0.292)	0.0432 (0.367)	0.209 (0.851)	0.00688 (0.0998)	0.135 (0.709)	0.00297 (0.0527)
SMARCA4	26 (5%)	487			0.0107 (0.139)	0.103 (0.606)	0.243 (0.878)	0.795 (1.00)	0.328 (0.953)	0.453 (1.00)	0.307 (0.931)	0.244 (0.878)	0.873 (1.00)	0.164 (0.782)
RBPJ	7 (1%)	506			1 (1.00)	0.181 (0.808)	0.255 (0.89)	0.181 (0.808)	0.439 (1.00)	8e-05 (0.00226)	0.33 (0.953)	0.0277 (0.274)	0.118 (0.645)	0.445 (1.00)
ZMIZ1	9 (2%)	504			0.0512 (0.417)	0.33 (0.953)	0.625 (1.00)	0.794 (1.00)	0.526 (1.00)	0.301 (0.931)	0.476 (1.00)	0.678 (1.00)	0.0189 (0.215)	0.42 (1.00)
PRX	10 (2%)	503			0.113 (0.633)	0.0327 (0.299)	0.244 (0.878)	0.0282 (0.276)	0.386 (1.00)	0.0601 (0.445)	0.539 (1.00)	0.00117 (0.0241)	0.185 (0.813)	0.0733 (0.499)
WRN	5 (1%)	508			0.207 (0.851)	0.0762 (0.506)			0.0304 (0.29)	0.0161 (0.193)	0.0562 (0.424)	1 (1.00)	0.0442 (0.373)	0.455 (1.00)
MYT1	6 (1%)	507			0.0153 (0.186)	0.207 (0.851)			0.447 (1.00)	0.032 (0.298)	0.429 (1.00)	0.758 (1.00)	0.453 (1.00)	0.94 (1.00)
RBBP6	6 (1%)	507			0.582 (1.00)	0.323 (0.953)			0.028 (0.276)	0.00627 (0.0931)	0.282 (0.906)	0.063 (0.457)	0.0836 (0.52)	0.175 (0.799)
TPTE2	5 (1%)	508			0.00429 (0.0702)	0.166 (0.784)			0.12 (0.649)	0.33 (0.953)	1 (1.00)	0.848 (1.00)	0.532 (1.00)	0.927 (1.00)
MTMR1	4 (1%)	509			0.055 (0.419)	0.306 (0.931)			1 (1.00)	0.0232 (0.248)	0.438 (1.00)	0.0756 (0.506)	0.332 (0.953)	0.918 (1.00)
CNOT4	5 (1%)	508			0.253 (0.89)	0.559 (1.00)	0.888 (1.00)	0.61 (1.00)	0.3 (0.931)	0.00959 (0.127)	0.115 (0.638)	0.117 (0.645)	0.335 (0.953)	0.451 (1.00)
CUL4B	10 (2%)	503			0.294 (0.923)	0.0467 (0.386)	0.237 (0.871)	1 (1.00)	0.091 (0.558)	0.0713 (0.495)	0.186 (0.815)	0.0071 (0.101)	1 (1.00)	0.379 (1)
PHF3	8 (2%)	505			0.018 (0.21)	0.694 (1.00)	0.706 (1.00)	0.794 (1.00)	0.261 (0.89)	0.588 (1.00)	0.0954 (0.574)	0.262 (0.89)	0.514 (1.00)	0.874 (1.00)
AEBP1	4 (1%)	509			0.361 (0.978)	0.398 (1.00)	0.234 (0.87)	0.345 (0.953)	0.279 (0.904)	0.0189 (0.215)	0.486 (1.00)	0.422 (1.00)	0.0771 (0.506)	0.391 (1.00)
SETD2	10 (2%)	503			0.0399 (0.346)	0.0631 (0.457)	0.933 (1.00)	1 (1.00)	0.00035 (0.00864)	0.053 (0.417)	0.603 (1.00)	0.0921 (0.562)	0.854 (1.00)	0.379 (1)
TPM1	5 (1%)	508			0.251 (0.889)	0.0942 (0.571)	0.415 (1.00)	0.263 (0.89)	0.472 (1.00)	0.039 (0.345)	0.224 (0.856)	0.0713 (0.495)	0.00303 (0.0531)	0.061 (0.449)
MYH8	14 (3%)	499			0.0796 (0.51)	0.184 (0.813)	0.597 (1.00)	0.177 (0.801)	0.219 (0.855)	0.0234 (0.248)	0.853 (1.00)	0.255 (0.89)	0.838 (1.00)	0.774 (1.00)
STAG2	4 (1%)	509			0.0529 (0.417)	0.0294 (0.284)	1 (1.00)	0.609 (1.00)	0.143 (0.734)	0.119 (0.646)	0.592 (1.00)	0.0134 (0.167)	0.47 (1.00)	0.234 (0.87)
HOOK1	3 (1%)	510			1 (1.00)	0.68 (1.00)			0.277 (0.904)	0.00351 (0.06)	0.327 (0.953)	0.153 (0.755)	1 (1.00)	0.777 (1.00)
NR1H3	4 (1%)	509			0.455 (1.00)	0.302 (0.931)	0.24 (0.876)	1 (1.00)	0.0719 (0.496)	0.0578 (0.431)	0.0801 (0.51)	0.0135 (0.167)	0.473 (1.00)	0.236 (0.87)
AMPD1	4 (1%)	509			0.0556 (0.422)	0.202 (0.848)			0.926 (1.00)	0.00792 (0.108)	0.4 (1.00)	0.341 (0.953)	0.165 (0.784)	0.917 (1.00)
HLA-DRA	3 (1%)	510			0.0126 (0.159)	0.542 (1.00)			0.346 (0.953)	0.0727 (0.499)	0.188 (0.823)	0.154 (0.755)	0.306 (0.931)	0.777 (1.00)
ALPP	5 (1%)	508			0.531 (1.00)	0.466 (1.00)			0.00058 (0.0135)	0.582 (1.00)	0.374 (0.997)	0.847 (1.00)	0.53 (1.00)	0.818 (1.00)
IGSF8	4 (1%)	509			0.362 (0.978)	0.654 (1.00)			1 (1.00)	0.00711 (0.101)	0.403 (1.00)	0.151 (0.755)	0.0774 (0.506)	0.162 (0.778)
ARID1A	20 (4%)	493			0.693 (1.00)	0.0791 (0.51)	0.317 (0.951)	0.7 (1.00)	0.0324 (0.299)	0.142 (0.734)	0.314 (0.945)	0.606 (1.00)	0.0837 (0.52)	0.0305 (0.29)
STK19	10 (2%)	503			0.421 (1.00)	0.111 (0.627)	0.0754 (0.506)	0.463 (1.00)	0.298 (0.931)	0.717 (1.00)	0.167 (0.784)	0.543 (1.00)	0.923 (1.00)	0.842 (1.00)
TCF12	15 (3%)	498			0.674 (1.00)	0.582 (1.00)	0.351 (0.964)	0.608 (1.00)	0.816 (1.00)	0.476 (1.00)	0.697 (1.00)	0.515 (1.00)	1 (1.00)	0.514 (1.00)
TRERF1	6 (1%)	507			0.246 (0.88)	0.125 (0.666)	0.782 (1.00)	0.347 (0.953)	0.392 (1.00)	0.577 (1.00)	0.391 (1.00)	0.758 (1.00)	0.105 (0.607)	0.353 (0.964)
SRPX	4 (1%)	509			0.223 (0.855)	0.107 (0.615)	0.439 (1.00)	1 (1.00)	0.209 (0.851)	0.142 (0.734)	0.273 (0.9)	0.195 (0.837)	0.397 (1.00)	0.0622 (0.454)
EMG1	7 (1%)	506			0.796 (1.00)	0.498 (1.00)	0.126 (0.666)	1 (1.00)	0.254 (0.89)	0.139 (0.723)	0.16 (0.778)	0.288 (0.916)	0.896 (1.00)	0.384 (1.00)
TNRC18	10 (2%)	503			0.774 (1.00)	0.099 (0.586)	0.844 (1.00)	0.671 (1.00)	0.131 (0.689)	0.401 (1.00)	0.511 (1.00)	0.182 (0.808)	1 (1.00)	0.345 (0.953)
DNMT3A	10 (2%)	503			0.662 (1.00)	0.646 (1.00)	0.684 (1.00)	0.839 (1.00)	0.634 (1.00)	0.941 (1.00)	0.481 (1.00)	0.045 (0.375)	0.923 (1.00)	0.971 (1.00)
HTRA2	5 (1%)	508			0.0306 (0.29)	0.421 (1.00)	0.379 (1)	1 (1.00)	0.952 (1.00)	0.641 (1.00)	0.349 (0.958)	0.725 (1.00)	0.556 (1.00)	0.47 (1.00)
ZNF709	4 (1%)	509			0.69 (1.00)	1 (1.00)	1 (1.00)	1 (1.00)	0.221 (0.855)	0.23 (0.862)	1 (1.00)	0.681 (1.00)	0.271 (0.9)	1 (1.00)
NRAS	4 (1%)	509			0.563 (1.00)	0.508 (1.00)			0.417 (1.00)	0.106 (0.613)	0.303 (0.931)	0.683 (1.00)	0.336 (0.953)	0.761 (1.00)
ZNF292	14 (3%)	499			0.115 (0.637)	0.205 (0.851)	0.284 (0.911)	0.451 (1.00)	0.747 (1.00)	0.0578 (0.431)	0.428 (1.00)	0.29 (0.92)	0.0832 (0.52)	0.0544 (0.419)
GAGE2D	5 (1%)	508			1 (1.00)	1 (1.00)	0.413 (1.00)	1 (1.00)	0.677 (1.00)	0.65 (1.00)	0.763 (1.00)	1 (1.00)	0.742 (1.00)	0.291 (0.922)
ARID2	11 (2%)	502			0.86 (1.00)	0.267 (0.891)	0.258 (0.89)	0.181 (0.808)	0.461 (1.00)	0.651 (1.00)	0.603 (1.00)	0.345 (0.953)	0.479 (1.00)	0.461 (1.00)
ZNF512B	5 (1%)	508			0.453 (1.00)	0.819 (1.00)	0.625 (1.00)	0.61 (1.00)	1 (1.00)	0.852 (1.00)	1 (1.00)	1 (1.00)	0.46 (1.00)	0.248 (0.882)
PPL	6 (1%)	507			0.772 (1.00)	1 (1.00)			0.843 (1.00)	0.247 (0.882)	0.144 (0.735)	0.758 (1.00)	0.329 (0.953)	0.726 (1.00)
NKD2	4 (1%)	509			1 (1.00)	0.879 (1.00)			0.639 (1.00)	0.464 (1.00)	0.364 (0.98)	1 (1.00)	1 (1.00)	0.839 (1.00)
IRS4	7 (1%)	506			0.082 (0.517)	0.375 (0.998)	0.843 (1.00)	0.261 (0.89)	0.6 (1.00)	0.135 (0.709)	0.415 (1.00)	0.692 (1.00)	0.267 (0.891)	1 (1.00)
SPTAN1	5 (1%)	508			0.726 (1.00)	0.465 (1.00)	0.842 (1.00)	0.668 (1.00)	0.829 (1.00)	0.194 (0.836)	0.766 (1.00)	0.529 (1.00)	0.454 (1.00)	1 (1.00)
CIB1	4 (1%)	509			0.824 (1.00)	1 (1.00)	0.338 (0.953)	0.608 (1.00)	0.604 (1.00)	0.174 (0.799)	0.219 (0.855)	0.0447 (0.375)	0.118 (0.646)	0.322 (0.953)
EIF1AX	4 (1%)	509			0.363 (0.979)	0.263 (0.89)	0.41 (1.00)	0.261 (0.89)	0.838 (1.00)	0.512 (1.00)	0.762 (1.00)	0.265 (0.89)	0.394 (1.00)	0.0777 (0.506)
SCN4A	6 (1%)	507			0.114 (0.635)	0.346 (0.953)	0.782 (1.00)	1 (1.00)	0.487 (1.00)	0.11 (0.625)	0.571 (1.00)	0.868 (1.00)	0.0688 (0.484)	0.414 (1.00)
DLC1	6 (1%)	507			0.0714 (0.495)	0.235 (0.87)	0.574 (1.00)	1 (1.00)	0.446 (1.00)	0.528 (1.00)	0.893 (1.00)	0.152 (0.755)	0.782 (1.00)	0.139 (0.723)
TMEM216	3 (1%)	510			0.254 (0.89)	1 (1.00)	0.791 (1.00)	0.793 (1.00)	1 (1.00)	0.448 (1.00)	0.52 (1.00)	0.603 (1.00)	0.306 (0.931)	0.668 (1.00)
SMARCB1	4 (1%)	509			0.822 (1.00)	0.881 (1.00)	0.0399 (0.346)	0.43 (1.00)	0.928 (1.00)	0.594 (1.00)	0.438 (1.00)	0.683 (1.00)	0.076 (0.506)	0.394 (1.00)
NEU2	5 (1%)	508			0.534 (1.00)	0.818 (1.00)			0.0787 (0.509)	0.87 (1.00)	0.305 (0.931)	1 (1.00)	0.456 (1.00)	0.71 (1.00)
MAPK15	4 (1%)	509			0.36 (0.976)	0.657 (1.00)	0.198 (0.838)	1 (1.00)	1 (1.00)	1 (1.00)	0.539 (1.00)	0.343 (0.953)	1 (1.00)	0.524 (1.00)
TPX2	5 (1%)	508			1 (1.00)	0.816 (1.00)			0.828 (1.00)	0.388 (1.00)	0.487 (1.00)	0.0732 (0.499)	0.169 (0.786)	0.32 (0.953)
SLC12A7	7 (1%)	506			0.167 (0.784)	0.404 (1.00)	0.21 (0.851)	0.812 (1.00)	0.921 (1.00)	0.862 (1.00)	0.87 (1.00)	0.786 (1.00)	0.894 (1.00)	1 (1.00)
PLXNA3	9 (2%)	504			0.21 (0.851)	0.271 (0.9)	0.309 (0.935)	0.42 (1.00)	0.2 (0.841)	0.311 (0.939)	0.352 (0.964)	0.228 (0.861)	0.481 (1.00)	0.876 (1.00)
RET	7 (1%)	506			0.553 (1.00)	0.32 (0.953)	0.286 (0.915)	0.431 (1.00)	0.374 (0.997)	0.445 (1.00)	0.709 (1.00)	0.153 (0.755)	0.148 (0.745)	0.254 (0.89)
ZNF148	4 (1%)	509			0.222 (0.855)	0.144 (0.734)			0.606 (1.00)	0.232 (0.867)	0.591 (1.00)	0.265 (0.891)	0.696 (1.00)	0.758 (1.00)
HDAC2	4 (1%)	509			0.36 (0.976)	0.143 (0.734)	0.728 (1.00)	0.265 (0.89)	0.606 (1.00)	0.177 (0.801)	0.219 (0.855)	0.681 (1.00)	0.164 (0.782)	0.161 (0.778)
MED9	3 (1%)	510			0.176 (0.799)	0.371 (0.994)			0.217 (0.855)	0.849 (1.00)	0.88 (1.00)	0.795 (1.00)	0.648 (1.00)	0.512 (1.00)
DDX5	5 (1%)	508			1 (1.00)	1 (1.00)	0.933 (1.00)	0.84 (1.00)	0.617 (1.00)	0.485 (1.00)	0.263 (0.89)	0.443 (1.00)	0.0276 (0.274)	0.317 (0.951)
SLC6A3	9 (2%)	504			0.703 (1.00)	0.877 (1.00)	0.326 (0.953)	0.0337 (0.306)	0.737 (1.00)	0.487 (1.00)	0.176 (0.799)	0.508 (1.00)	0.705 (1.00)	0.537 (1.00)
C4BPA	6 (1%)	507			0.329 (0.953)	0.3 (0.931)			0.904 (1.00)	0.382 (1)	0.731 (1.00)	0.507 (1.00)	1 (1.00)	1 (1.00)
MATK	6 (1%)	507			1 (1.00)	0.915 (1.00)	0.842 (1.00)	1 (1.00)	0.236 (0.87)	0.167 (0.784)	0.429 (1.00)	0.866 (1.00)	0.456 (1.00)	0.412 (1.00)
SMOC1	3 (1%)	510			1 (1.00)	1 (1.00)			1 (1.00)	0.817 (1.00)	0.598 (1.00)	1 (1.00)	0.652 (1.00)	0.185 (0.813)
NAP1L2	4 (1%)	509			0.687 (1.00)	1 (1.00)			0.381 (1)	0.0682 (0.483)	1 (1.00)	0.832 (1.00)	1 (1.00)	1 (1.00)
CD99L2	4 (1%)	509			0.362 (0.978)	0.123 (0.661)	0.626 (1.00)	0.608 (1.00)	0.603 (1.00)	0.229 (0.862)	0.217 (0.855)	1 (1.00)	0.697 (1.00)	0.58 (1.00)
SELE	6 (1%)	507			0.278 (0.904)	0.236 (0.87)	0.344 (0.953)	0.55 (1.00)	0.7 (1.00)	0.38 (1)	0.732 (1.00)	0.0654 (0.468)	0.453 (1.00)	1 (1.00)
TMEM184A	3 (1%)	510			0.464 (1.00)	0.302 (0.931)			0.585 (1.00)	0.175 (0.799)	0.877 (1.00)	0.231 (0.864)	0.415 (1.00)	0.509 (1.00)
FHOD1	6 (1%)	507			0.671 (1.00)	0.277 (0.904)	1 (1.00)	0.611 (1.00)	0.963 (1.00)	0.82 (1.00)	0.892 (1.00)	0.756 (1.00)	0.457 (1.00)	0.698 (1.00)
HTR3A	7 (1%)	506			0.617 (1.00)	0.153 (0.755)	0.256 (0.89)	0.809 (1.00)	0.659 (1.00)	0.382 (1)	0.17 (0.791)	0.243 (0.878)	0.574 (1.00)	0.871 (1.00)
FGD6	4 (1%)	509			0.221 (0.855)	0.881 (1.00)	0.255 (0.89)	0.182 (0.808)	0.542 (1.00)	0.723 (1.00)	0.277 (0.904)	0.263 (0.89)	1 (1.00)	1 (1.00)
CD72	3 (1%)	510			1 (1.00)	0.541 (1.00)			0.343 (0.953)	0.511 (1.00)	0.19 (0.825)	0.152 (0.755)	0.11 (0.625)	0.0275 (0.274)
NKPD1	3 (1%)	510			0.609 (1.00)	1 (1.00)			1 (1.00)	0.547 (1.00)	0.681 (1.00)	0.794 (1.00)	0.208 (0.851)	0.776 (1.00)
GPR133	4 (1%)	509			0.457 (1.00)	0.306 (0.931)			0.0243 (0.255)	0.584 (1.00)	1 (1.00)	0.685 (1.00)	0.0759 (0.506)	0.396 (1.00)
ROBO3	5 (1%)	508			0.621 (1.00)	0.903 (1.00)			0.828 (1.00)	0.71 (1.00)	0.401 (1.00)	0.289 (0.92)	1 (1.00)	0.929 (1.00)
PDE8A	6 (1%)	507			0.282 (0.906)	0.238 (0.871)	0.841 (1.00)	0.671 (1.00)	0.7 (1.00)	0.703 (1.00)	0.731 (1.00)	0.216 (0.855)	0.781 (1.00)	0.767 (1.00)
EEF1D	3 (1%)	510			1 (1.00)	0.539 (1.00)	1 (1.00)	0.611 (1.00)	0.414 (1.00)	0.548 (1.00)	1 (1.00)	0.793 (1.00)	0.413 (1.00)	0.587 (1.00)
MET	7 (1%)	506			0.699 (1.00)	0.826 (1.00)	0.785 (1.00)	1 (1.00)	0.922 (1.00)	0.922 (1.00)	1 (1.00)	0.509 (1.00)	0.783 (1.00)	0.94 (1.00)
SNX31	4 (1%)	509			0.219 (0.855)	0.306 (0.931)			0.715 (1.00)	0.734 (1.00)	0.591 (1.00)	0.342 (0.953)	0.413 (1.00)	0.512 (1.00)
G6PC	6 (1%)	507			0.329 (0.953)	0.146 (0.741)	0.842 (1.00)	0.667 (1.00)	0.611 (1.00)	0.0803 (0.51)	0.429 (1.00)	0.151 (0.755)	0.293 (0.923)	0.765 (1.00)
FOXQ1	4 (1%)	509			0.16 (0.776)	0.226 (0.857)	0.627 (1.00)	0.192 (0.832)	0.927 (1.00)	0.583 (1.00)	0.401 (1.00)	0.682 (1.00)	0.0771 (0.506)	0.396 (1.00)
DST	12 (2%)	501			0.235 (0.87)	0.579 (1.00)	0.497 (1.00)	1 (1.00)	0.85 (1.00)	0.961 (1.00)	0.418 (1.00)	0.932 (1.00)	0.406 (1.00)	0.27 (0.899)
USP6	6 (1%)	507			0.33 (0.953)	0.507 (1.00)	0.888 (1.00)	0.792 (1.00)	0.447 (1.00)	0.138 (0.721)	0.728 (1.00)	0.218 (0.855)	1 (1.00)	0.552 (1.00)
GLYAT	4 (1%)	509			0.823 (1.00)	0.88 (1.00)			0.639 (1.00)	0.721 (1.00)	0.195 (0.837)	0.265 (0.89)	0.838 (1.00)	0.698 (1.00)
DIAPH1	4 (1%)	509			0.458 (1.00)	0.228 (0.861)	1 (1.00)	0.612 (1.00)	0.839 (1.00)	0.111 (0.627)	0.0813 (0.514)	1 (1.00)	0.475 (1.00)	1 (1.00)
ZMYM2	7 (1%)	506			0.618 (1.00)	0.664 (1.00)	0.525 (1.00)	0.427 (1.00)	0.627 (1.00)	0.321 (0.953)	0.122 (0.658)	0.211 (0.852)	0.272 (0.9)	0.367 (0.986)
HCFC1	7 (1%)	506			0.702 (1.00)	0.378 (1)	1 (1.00)	0.608 (1.00)	0.245 (0.878)	0.612 (1.00)	0.221 (0.855)	0.244 (0.878)	0.893 (1.00)	0.909 (1.00)
MST1	4 (1%)	509			0.22 (0.855)	0.303 (0.931)			0.545 (1.00)	0.272 (0.9)	0.59 (1.00)	0.344 (0.953)	0.84 (1.00)	0.522 (1.00)
TNFSF14	5 (1%)	508			0.105 (0.607)	0.0284 (0.277)			0.0883 (0.543)	0.0442 (0.373)	0.766 (1.00)	0.358 (0.976)	0.332 (0.953)	0.0697 (0.489)
DNAH7	10 (2%)	503			0.846 (1.00)	0.644 (1.00)	0.257 (0.89)	0.181 (0.808)	0.498 (1.00)	0.342 (0.953)	0.639 (1.00)	0.615 (1.00)	0.592 (1.00)	0.606 (1.00)
ENGASE	5 (1%)	508			1 (1.00)	0.816 (1.00)			0.256 (0.89)	0.254 (0.89)	0.673 (1.00)	0.528 (1.00)	1 (1.00)	1 (1.00)
VSIG4	6 (1%)	507			0.207 (0.851)	0.169 (0.786)	0.451 (1.00)	0.441 (1.00)	0.771 (1.00)	0.501 (1.00)	0.767 (1.00)	0.584 (1.00)	0.688 (1.00)	0.394 (1.00)
KRT3	4 (1%)	509			0.823 (1.00)	0.879 (1.00)	0.285 (0.912)	0.433 (1.00)	0.641 (1.00)	0.734 (1.00)	0.275 (0.903)	0.197 (0.838)	0.394 (1.00)	0.213 (0.852)
MUC17	27 (5%)	486			0.65 (1.00)	0.725 (1.00)	0.674 (1.00)	0.586 (1.00)	0.225 (0.857)	0.104 (0.607)	0.0271 (0.274)	0.0411 (0.351)	0.0264 (0.273)	0.0617 (0.452)
ABCA7	9 (2%)	504			0.704 (1.00)	0.382 (1)	0.124 (0.665)	0.226 (0.857)	0.266 (0.891)	0.212 (0.852)	1 (1.00)	0.0546 (0.419)	0.0978 (0.581)	0.25 (0.887)
FOXK1	4 (1%)	509			0.0532 (0.417)	0.0799 (0.51)	0.674 (1.00)	1 (1.00)	0.928 (1.00)	0.575 (1.00)	0.832 (1.00)	0.833 (1.00)	0.838 (1.00)	0.394 (1.00)
SLFN11	4 (1%)	509			0.824 (1.00)	0.879 (1.00)	0.56 (1.00)	0.797 (1.00)	0.313 (0.943)	0.714 (1.00)	0.592 (1.00)	0.265 (0.89)	0.473 (1.00)	0.757 (1.00)
MX2	4 (1%)	509			1 (1.00)	0.658 (1.00)			1 (1.00)	0.664 (1.00)	0.368 (0.987)	1 (1.00)	1 (1.00)	0.639 (1.00)
SLC6A4	5 (1%)	508			0.531 (1.00)	0.206 (0.851)	0.0404 (0.348)	0.429 (1.00)	0.724 (1.00)	0.163 (0.782)	0.927 (1.00)	0.848 (1.00)	0.871 (1.00)	0.212 (0.852)
KRT15	6 (1%)	507			0.331 (0.953)	1 (1.00)			0.487 (1.00)	0.462 (1.00)	0.517 (1.00)	0.868 (1.00)	1 (1.00)	1 (1.00)
FMR1	5 (1%)	508			0.451 (1.00)	0.126 (0.666)			0.198 (0.838)	0.453 (1.00)	0.241 (0.876)	0.36 (0.976)	0.334 (0.953)	1 (1.00)
SON	8 (2%)	505			0.222 (0.855)	0.107 (0.614)	0.495 (1.00)	0.218 (0.855)	0.772 (1.00)	0.713 (1.00)	0.828 (1.00)	0.52 (1.00)	0.642 (1.00)	0.158 (0.773)
TTC30B	6 (1%)	507			0.769 (1.00)	0.74 (1.00)			0.794 (1.00)	0.403 (1.00)	0.0757 (0.506)	0.667 (1.00)	0.454 (1.00)	0.392 (1.00)
FANCD2	7 (1%)	506			0.55 (1.00)	0.197 (0.838)	0.0399 (0.346)	0.429 (1.00)	0.103 (0.607)	0.609 (1.00)	0.87 (1.00)	0.331 (0.953)	0.802 (1.00)	0.22 (0.855)
RGL2	4 (1%)	509			0.822 (1.00)	0.878 (1.00)			0.714 (1.00)	0.0353 (0.317)	0.404 (1.00)	0.34 (0.953)	0.694 (1.00)	0.58 (1.00)
TYRP1	4 (1%)	509			0.456 (1.00)	0.305 (0.931)			0.108 (0.616)	0.273 (0.9)	0.402 (1.00)	0.344 (0.953)	0.698 (1.00)	0.357 (0.975)
SLC25A5	4 (1%)	509			0.456 (1.00)	0.229 (0.862)			0.928 (1.00)	0.423 (1.00)	0.834 (1.00)	0.684 (1.00)	0.472 (1.00)	0.525 (1.00)
NGEF	6 (1%)	507			0.872 (1.00)	0.64 (1.00)	0.239 (0.875)	1 (1.00)	0.715 (1.00)	0.923 (1.00)	0.431 (1.00)	0.869 (1.00)	0.293 (0.923)	0.412 (1.00)
YIPF1	3 (1%)	510			1 (1.00)	0.675 (1.00)	0.561 (1.00)	1 (1.00)	0.0835 (0.52)	0.0543 (0.419)	0.522 (1.00)	0.792 (1.00)	0.208 (0.851)	1 (1.00)
PDHA1	5 (1%)	508			0.208 (0.851)	0.512 (1.00)	0.0531 (0.417)	0.811 (1.00)	0.676 (1.00)	0.459 (1.00)	0.928 (1.00)	0.848 (1.00)	0.532 (1.00)	0.397 (1.00)
ASXL2	3 (1%)	510			0.467 (1.00)	0.302 (0.931)			0.83 (1.00)	0.318 (0.953)	0.521 (1.00)	0.793 (1.00)	0.205 (0.851)	1 (1.00)
CDH3	3 (1%)	510			0.176 (0.799)	0.675 (1.00)			0.829 (1.00)	0.281 (0.906)	0.523 (1.00)	0.795 (1.00)	0.21 (0.851)	1 (1.00)
NADSYN1	3 (1%)	510			0.104 (0.607)	0.539 (1.00)			0.344 (0.953)	0.0735 (0.499)	0.384 (1.00)	0.154 (0.755)	0.648 (1.00)	0.437 (1.00)
LHFPL1	4 (1%)	509			0.69 (1.00)	1 (1.00)			0.279 (0.904)	0.323 (0.953)	0.304 (0.931)	0.423 (1.00)	0.077 (0.506)	0.579 (1.00)
SLC10A7	3 (1%)	510			1 (1.00)	0.54 (1.00)			0.499 (1.00)	0.496 (1.00)	0.191 (0.83)	0.43 (1.00)	1 (1.00)	0.887 (1.00)
CXCR2	4 (1%)	509			0.688 (1.00)	0.759 (1.00)	0.673 (1.00)	1 (1.00)	0.488 (1.00)	0.298 (0.931)	1 (1.00)	0.683 (1.00)	0.078 (0.506)	0.394 (1.00)
SEC14L4	3 (1%)	510			0.609 (1.00)	0.541 (1.00)			0.344 (0.953)	0.515 (1.00)	0.19 (0.825)	0.153 (0.755)	0.112 (0.63)	0.0272 (0.274)
ANKRD17	6 (1%)	507			0.143 (0.734)	0.321 (0.953)	0.413 (1.00)	0.262 (0.89)	0.962 (1.00)	0.397 (1.00)	0.844 (1.00)	0.867 (1.00)	0.0684 (0.483)	0.523 (1.00)
MAST3	5 (1%)	508			0.852 (1.00)	0.376 (0.999)			0.342 (0.953)	0.455 (1.00)	0.491 (1.00)	0.44 (1.00)	0.455 (1.00)	0.716 (1.00)
AMMECR1	5 (1%)	508			0.38 (1)	0.613 (1.00)			0.505 (1.00)	0.0492 (0.405)	0.165 (0.784)	0.526 (1.00)	0.198 (0.838)	0.451 (1.00)
NEO1	7 (1%)	506			1 (1.00)	0.736 (1.00)	0.415 (1.00)	0.261 (0.89)	0.71 (1.00)	0.821 (1.00)	0.77 (1.00)	1 (1.00)	0.0274 (0.274)	0.324 (0.953)
PACS1	3 (1%)	510			0.334 (0.953)	1 (1.00)			0.691 (1.00)	0.789 (1.00)	0.775 (1.00)	0.601 (1.00)	1 (1.00)	0.888 (1.00)
RGS3	6 (1%)	507			0.379 (1)	0.197 (0.838)	0.626 (1.00)	0.194 (0.836)	0.556 (1.00)	0.0242 (0.255)	0.215 (0.855)	0.755 (1.00)	0.293 (0.923)	0.94 (1.00)

'IDH1 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.224 (Fisher's exact test), Q value = 0.86

Table S1. Gene #1: 'IDH1 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	9	10	8
IDH1 MUTATED	9	7	7
IDH1 WILD-TYPE	0	3	1

'IDH1 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.883 (Fisher's exact test), Q value = 1

Table S2. Gene #1: 'IDH1 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	7	7	7	6
IDH1 MUTATED	6	6	5	6
IDH1 WILD-TYPE	1	1	2	0

'IDH1 MUTATION STATUS' versus 'CN_CNMF'

P value = 1e-05 (Fisher's exact test), Q value = 0.00032

Table S3. Gene #1: 'IDH1 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	169	120	221
IDH1 MUTATED	158	45	193
IDH1 WILD-TYPE	11	75	28

Figure S1. Get High-res Image Gene #1: 'IDH1 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

'IDH1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1e-05 (Fisher's exact test), Q value = 0.00032

Table S4. Gene #1: 'IDH1 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	222	81	168	42
IDH1 MUTATED	218	6	155	19
IDH1 WILD-TYPE	4	75	13	23

Figure S2. Get High-res Image Gene #1: 'IDH1 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

'IDH1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 1e-05 (Fisher's exact test), Q value = 0.00032

Table S5. Gene #1: 'IDH1 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	52	62	68	74
IDH1 MUTATED	42	31	63	58
IDH1 WILD-TYPE	10	31	5	16

Figure S3. Get High-res Image Gene #1: 'IDH1 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

'IDH1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.00132 (Fisher's exact test), Q value = 0.027

Table S6. Gene #1: 'IDH1 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	67	131	58
IDH1 MUTATED	61	91	42
IDH1 WILD-TYPE	6	40	16

Figure S4. Get High-res Image Gene #1: 'IDH1 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

'IDH1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1e-05 (Fisher's exact test), Q value = 0.00032

Table S7. Gene #1: 'IDH1 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	132	109	109	133	30
IDH1 MUTATED	130	34	101	109	24
IDH1 WILD-TYPE	2	75	8	24	6

Figure S5. Get High-res Image Gene #1: 'IDH1 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

'IDH1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 1e-05 (Fisher's exact test), Q value = 0.00032

Table S8. Gene #1: 'IDH1 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	134	71	36	66	91	41	74
IDH1 MUTATED	132	2	32	50	84	37	61
IDH1 WILD-TYPE	2	69	4	16	7	4	13

Figure S6. Get High-res Image Gene #1: 'IDH1 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'IDH1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 6e-05 (Fisher's exact test), Q value = 0.0018

Table S9. Gene #1: 'IDH1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
IDH1 MUTATED	97	73	146	78
IDH1 WILD-TYPE	39	34	37	5

Figure S7. Get High-res Image Gene #1: 'IDH1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

'IDH1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 1e-05 (Fisher's exact test), Q value = 0.00032

Table S10. Gene #1: 'IDH1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
IDH1 MUTATED	207	152	35
IDH1 WILD-TYPE	15	32	68

Figure S8. Get High-res Image Gene #1: 'IDH1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

'IDH1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1e-05 (Fisher's exact test), Q value = 0.00032

Table S11. Gene #1: 'IDH1 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
IDH1 MUTATED	114	153	124
IDH1 WILD-TYPE	70	9	35

Figure S9. Get High-res Image Gene #1: 'IDH1 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

'IDH1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1e-05 (Fisher's exact test), Q value = 0.00032

Table S12. Gene #1: 'IDH1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
IDH1 MUTATED	84	129	161	17
IDH1 WILD-TYPE	6	9	27	72

Figure S10. Get High-res Image Gene #1: 'IDH1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

'TP53 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.0944 (Fisher's exact test), Q value = 0.57

Table S13. Gene #2: 'TP53 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	9	10	8
TP53 MUTATED	8	4	4
TP53 WILD-TYPE	1	6	4

'TP53 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.00597 (Fisher's exact test), Q value = 0.089

Table S14. Gene #2: 'TP53 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	7	7	7	6
TP53 MUTATED	5	7	1	3
TP53 WILD-TYPE	2	0	6	3

Figure S11. Get High-res Image Gene #2: 'TP53 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

'TP53 MUTATION STATUS' versus 'CN_CNMF'

P value = 1e-05 (Fisher's exact test), Q value = 0.00032

Table S15. Gene #2: 'TP53 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	169	120	221
TP53 MUTATED	156	47	45
TP53 WILD-TYPE	13	73	176

Figure S12. Get High-res Image Gene #2: 'TP53 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

'TP53 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1e-05 (Fisher's exact test), Q value = 0.00032

Table S16. Gene #2: 'TP53 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	222	81	168	42
TP53 MUTATED	213	15	7	13
TP53 WILD-TYPE	9	66	161	29

Figure S13. Get High-res Image Gene #2: 'TP53 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

'TP53 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.0316 (Fisher's exact test), Q value = 0.3

Table S17. Gene #2: 'TP53 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	52	62	68	74
TP53 MUTATED	33	30	41	30
TP53 WILD-TYPE	19	32	27	44

Figure S14. Get High-res Image Gene #2: 'TP53 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

'TP53 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.591 (Fisher's exact test), Q value = 1

Table S18. Gene #2: 'TP53 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	67	131	58
TP53 MUTATED	37	70	27
TP53 WILD-TYPE	30	61	31

'TP53 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1e-05 (Fisher's exact test), Q value = 0.00032

Table S19. Gene #2: 'TP53 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	132	109	109	133	30
TP53 MUTATED	129	40	7	58	14
TP53 WILD-TYPE	3	69	102	75	16

Figure S15. Get High-res Image Gene #2: 'TP53 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

'TP53 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 1e-05 (Fisher's exact test), Q value = 0.00032

Table S20. Gene #2: 'TP53 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	134	71	36	66	91	41	74
TP53 MUTATED	129	8	1	48	4	38	20
TP53 WILD-TYPE	5	63	35	18	87	3	54

Figure S16. Get High-res Image Gene #2: 'TP53 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'TP53 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1e-05 (Fisher's exact test), Q value = 0.00032

Table S21. Gene #2: 'TP53 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
TP53 MUTATED	82	70	74	18
TP53 WILD-TYPE	54	37	109	65

Figure S17. Get High-res Image Gene #2: 'TP53 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

'TP53 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 2e-05 (Fisher's exact test), Q value = 0.00063

Table S22. Gene #2: 'TP53 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
TP53 MUTATED	133	71	40
TP53 WILD-TYPE	89	113	63

Figure S18. Get High-res Image Gene #2: 'TP53 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

'TP53 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.0527 (Fisher's exact test), Q value = 0.42

Table S23. Gene #2: 'TP53 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
TP53 MUTATED	98	79	64
TP53 WILD-TYPE	86	83	95

'TP53 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1e-05 (Fisher's exact test), Q value = 0.00032

Table S24. Gene #2: 'TP53 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
TP53 MUTATED	79	56	85	21
TP53 WILD-TYPE	11	82	103	68

Figure S19. Get High-res Image Gene #2: 'TP53 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

'ATRX MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.0253 (Fisher's exact test), Q value = 0.26

Table S25. Gene #3: 'ATRX MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	9	10	8
ATRX MUTATED	8	3	3
ATRX WILD-TYPE	1	7	5

Figure S20. Get High-res Image Gene #3: 'ATRX MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

'ATRX MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.119 (Fisher's exact test), Q value = 0.65

Table S26. Gene #3: 'ATRX MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	7	7	7	6
ATRX MUTATED	5	5	1	3
ATRX WILD-TYPE	2	2	6	3

'ATRX MUTATION STATUS' versus 'CN_CNMF'

P value = 1e-05 (Fisher's exact test), Q value = 0.00032

Table S27. Gene #3: 'ATRX MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	169	120	221
ATRX MUTATED	129	34	32
ATRX WILD-TYPE	40	86	189

Figure S21. Get High-res Image Gene #3: 'ATRX MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

'ATRX MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1e-05 (Fisher's exact test), Q value = 0.00032

Table S28. Gene #3: 'ATRX MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	222	81	168	42
ATRX MUTATED	171	8	3	13
ATRX WILD-TYPE	51	73	165	29

Figure S22. Get High-res Image Gene #3: 'ATRX MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

'ATRX MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.161 (Fisher's exact test), Q value = 0.78

Table S29. Gene #3: 'ATRX MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	52	62	68	74
ATRX MUTATED	27	23	34	27
ATRX WILD-TYPE	25	39	34	47

'ATRX MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.866 (Fisher's exact test), Q value = 1

Table S30. Gene #3: 'ATRX MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	67	131	58
ATRX MUTATED	31	55	25
ATRX WILD-TYPE	36	76	33

'ATRX MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1e-05 (Fisher's exact test), Q value = 0.00032

Table S31. Gene #3: 'ATRX MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	132	109	109	133	30
ATRX MUTATED	107	27	2	48	11
ATRX WILD-TYPE	25	82	107	85	19

Figure S23. Get High-res Image Gene #3: 'ATRX MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

'ATRX MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 1e-05 (Fisher's exact test), Q value = 0.00032

Table S32. Gene #3: 'ATRX MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	134	71	36	66	91	41	74
ATRX MUTATED	108	4	1	38	1	26	17
ATRX WILD-TYPE	26	67	35	28	90	15	57

Figure S24. Get High-res Image Gene #3: 'ATRX MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'ATRX MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1e-05 (Fisher's exact test), Q value = 0.00032

Table S33. Gene #3: 'ATRX MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
ATRX MUTATED	60	60	59	12
ATRX WILD-TYPE	76	47	124	71

Figure S25. Get High-res Image Gene #3: 'ATRX MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

'ATRX MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 3e-05 (Fisher's exact test), Q value = 0.00089

Table S34. Gene #3: 'ATRX MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
ATRX MUTATED	108	58	25
ATRX WILD-TYPE	114	126	78

Figure S26. Get High-res Image Gene #3: 'ATRX MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

'ATRX MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.257 (Fisher's exact test), Q value = 0.89

Table S35. Gene #3: 'ATRX MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
ATRX MUTATED	76	60	52
ATRX WILD-TYPE	108	102	107

'ATRX MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1e-05 (Fisher's exact test), Q value = 0.00032

Table S36. Gene #3: 'ATRX MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
ATRX MUTATED	62	43	69	14
ATRX WILD-TYPE	28	95	119	75

Figure S27. Get High-res Image Gene #3: 'ATRX MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

'CIC MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.0503 (Fisher's exact test), Q value = 0.41

Table S37. Gene #4: 'CIC MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	9	10	8
CIC MUTATED	0	5	2
CIC WILD-TYPE	9	5	6

'CIC MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.0029 (Fisher's exact test), Q value = 0.053

Table S38. Gene #4: 'CIC MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	7	7	7	6
CIC MUTATED	0	0	5	2
CIC WILD-TYPE	7	7	2	4

Figure S28. Get High-res Image Gene #4: 'CIC MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

'CIC MUTATION STATUS' versus 'CN_CNMF'

P value = 1e-05 (Fisher's exact test), Q value = 0.00032

Table S39. Gene #4: 'CIC MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	169	120	221
CIC MUTATED	1	5	102
CIC WILD-TYPE	168	115	119

Figure S29. Get High-res Image Gene #4: 'CIC MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

'CIC MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1e-05 (Fisher's exact test), Q value = 0.00032

Table S40. Gene #4: 'CIC MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	222	81	168	42
CIC MUTATED	0	1	104	3
CIC WILD-TYPE	222	80	64	39

Figure S30. Get High-res Image Gene #4: 'CIC MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

'CIC MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.00017 (Fisher's exact test), Q value = 0.0044

Table S41. Gene #4: 'CIC MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	52	62	68	74
CIC MUTATED	2	6	22	15
CIC WILD-TYPE	50	56	46	59

Figure S31. Get High-res Image Gene #4: 'CIC MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

'CIC MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.804 (Fisher's exact test), Q value = 1

Table S42. Gene #4: 'CIC MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	67	131	58
CIC MUTATED	10	25	10
CIC WILD-TYPE	57	106	48

'CIC MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1e-05 (Fisher's exact test), Q value = 0.00032

Table S43. Gene #4: 'CIC MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	132	109	109	133	30
CIC MUTATED	0	1	74	28	5
CIC WILD-TYPE	132	108	35	105	25

Figure S32. Get High-res Image Gene #4: 'CIC MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

'CIC MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 1e-05 (Fisher's exact test), Q value = 0.00032

Table S44. Gene #4: 'CIC MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	134	71	36	66	91	41	74
CIC MUTATED	0	0	23	0	60	1	24
CIC WILD-TYPE	134	71	13	66	31	40	50

Figure S33. Get High-res Image Gene #4: 'CIC MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'CIC MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1e-05 (Fisher's exact test), Q value = 0.00032

Table S45. Gene #4: 'CIC MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
CIC MUTATED	15	4	43	46
CIC WILD-TYPE	121	103	140	37

Figure S34. Get High-res Image Gene #4: 'CIC MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

'CIC MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 1e-05 (Fisher's exact test), Q value = 0.00032

Table S46. Gene #4: 'CIC MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
CIC MUTATED	55	51	2
CIC WILD-TYPE	167	133	101

Figure S35. Get High-res Image Gene #4: 'CIC MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

'CIC MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1e-05 (Fisher's exact test), Q value = 0.00032

Table S47. Gene #4: 'CIC MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
CIC MUTATED	11	61	36
CIC WILD-TYPE	173	101	123

Figure S36. Get High-res Image Gene #4: 'CIC MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

'CIC MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1e-05 (Fisher's exact test), Q value = 0.00032

Table S48. Gene #4: 'CIC MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
CIC MUTATED	2	62	43	1
CIC WILD-TYPE	88	76	145	88

Figure S37. Get High-res Image Gene #4: 'CIC MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

'NOTCH1 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.614 (Fisher's exact test), Q value = 1

Table S49. Gene #5: 'NOTCH1 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	9	10	8
NOTCH1 MUTATED	0	2	1
NOTCH1 WILD-TYPE	9	8	7

'NOTCH1 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.279 (Fisher's exact test), Q value = 0.9

Table S50. Gene #5: 'NOTCH1 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	7	7	7	6
NOTCH1 MUTATED	0	0	2	1
NOTCH1 WILD-TYPE	7	7	5	5

'NOTCH1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.00027 (Fisher's exact test), Q value = 0.0068

Table S51. Gene #5: 'NOTCH1 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	169	120	221
NOTCH1 MUTATED	6	5	31
NOTCH1 WILD-TYPE	163	115	190

Figure S38. Get High-res Image Gene #5: 'NOTCH1 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

'NOTCH1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1e-05 (Fisher's exact test), Q value = 0.00032

Table S52. Gene #5: 'NOTCH1 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	222	81	168	42
NOTCH1 MUTATED	9	1	32	0
NOTCH1 WILD-TYPE	213	80	136	42

Figure S39. Get High-res Image Gene #5: 'NOTCH1 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

'NOTCH1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.778 (Fisher's exact test), Q value = 1

Table S53. Gene #5: 'NOTCH1 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	52	62	68	74
NOTCH1 MUTATED	4	6	9	9
NOTCH1 WILD-TYPE	48	56	59	65

'NOTCH1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.897 (Fisher's exact test), Q value = 1

Table S54. Gene #5: 'NOTCH1 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	67	131	58
NOTCH1 MUTATED	6	15	7
NOTCH1 WILD-TYPE	61	116	51

'NOTCH1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1e-05 (Fisher's exact test), Q value = 0.00032

Table S55. Gene #5: 'NOTCH1 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	132	109	109	133	30
NOTCH1 MUTATED	3	3	21	15	0
NOTCH1 WILD-TYPE	129	106	88	118	30

Figure S40. Get High-res Image Gene #5: 'NOTCH1 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

'NOTCH1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 1e-05 (Fisher's exact test), Q value = 0.00032

Table S56. Gene #5: 'NOTCH1 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	134	71	36	66	91	41	74
NOTCH1 MUTATED	3	0	13	1	9	3	13
NOTCH1 WILD-TYPE	131	71	23	65	82	38	61

Figure S41. Get High-res Image Gene #5: 'NOTCH1 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'NOTCH1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 4e-04 (Fisher's exact test), Q value = 0.0096

Table S57. Gene #5: 'NOTCH1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
NOTCH1 MUTATED	4	3	21	13
NOTCH1 WILD-TYPE	132	104	162	70

Figure S42. Get High-res Image Gene #5: 'NOTCH1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

'NOTCH1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.00451 (Fisher's exact test), Q value = 0.072

Table S58. Gene #5: 'NOTCH1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
NOTCH1 MUTATED	16	23	2
NOTCH1 WILD-TYPE	206	161	101

Figure S43. Get High-res Image Gene #5: 'NOTCH1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

'NOTCH1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.00159 (Fisher's exact test), Q value = 0.031

Table S59. Gene #5: 'NOTCH1 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
NOTCH1 MUTATED	6	13	22
NOTCH1 WILD-TYPE	178	149	137

Figure S44. Get High-res Image Gene #5: 'NOTCH1 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

'NOTCH1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.00011 (Fisher's exact test), Q value = 0.003

Table S60. Gene #5: 'NOTCH1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
NOTCH1 MUTATED	3	14	24	0
NOTCH1 WILD-TYPE	87	124	164	89

Figure S45. Get High-res Image Gene #5: 'NOTCH1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

'EGFR MUTATION STATUS' versus 'CN_CNMF'

P value = 1e-05 (Fisher's exact test), Q value = 0.00032

Table S61. Gene #6: 'EGFR MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	169	120	221
EGFR MUTATED	0	32	3
EGFR WILD-TYPE	169	88	218

Figure S46. Get High-res Image Gene #6: 'EGFR MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

'EGFR MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1e-05 (Fisher's exact test), Q value = 0.00032

Table S62. Gene #6: 'EGFR MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	222	81	168	42
EGFR MUTATED	0	30	2	3
EGFR WILD-TYPE	222	51	166	39

Figure S47. Get High-res Image Gene #6: 'EGFR MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

'EGFR MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.0299 (Fisher's exact test), Q value = 0.29

Table S63. Gene #6: 'EGFR MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	52	62	68	74
EGFR MUTATED	1	9	2	4
EGFR WILD-TYPE	51	53	66	70

Figure S48. Get High-res Image Gene #6: 'EGFR MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

'EGFR MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.0189 (Fisher's exact test), Q value = 0.21

Table S64. Gene #6: 'EGFR MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	67	131	58
EGFR MUTATED	0	12	4
EGFR WILD-TYPE	67	119	54

Figure S49. Get High-res Image Gene #6: 'EGFR MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

'EGFR MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1e-05 (Fisher's exact test), Q value = 0.00032

Table S65. Gene #6: 'EGFR MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	132	109	109	133	30
EGFR MUTATED	0	26	2	5	2
EGFR WILD-TYPE	132	83	107	128	28

Figure S50. Get High-res Image Gene #6: 'EGFR MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

'EGFR MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 1e-05 (Fisher's exact test), Q value = 0.00032

Table S66. Gene #6: 'EGFR MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	134	71	36	66	91	41	74
EGFR MUTATED	0	25	1	6	0	1	2
EGFR WILD-TYPE	134	46	35	60	91	40	72

Figure S51. Get High-res Image Gene #6: 'EGFR MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'EGFR MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.0107 (Fisher's exact test), Q value = 0.14

Table S67. Gene #6: 'EGFR MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
EGFR MUTATED	11	11	13	0
EGFR WILD-TYPE	125	96	170	83

Figure S52. Get High-res Image Gene #6: 'EGFR MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

'EGFR MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 1e-05 (Fisher's exact test), Q value = 0.00032

Table S68. Gene #6: 'EGFR MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
EGFR MUTATED	1	9	25
EGFR WILD-TYPE	221	175	78

Figure S53. Get High-res Image Gene #6: 'EGFR MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

'EGFR MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1e-05 (Fisher's exact test), Q value = 0.00032

Table S69. Gene #6: 'EGFR MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
EGFR MUTATED	23	0	12
EGFR WILD-TYPE	161	162	147

Figure S54. Get High-res Image Gene #6: 'EGFR MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

'EGFR MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1e-05 (Fisher's exact test), Q value = 0.00032

Table S70. Gene #6: 'EGFR MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
EGFR MUTATED	0	0	8	27
EGFR WILD-TYPE	90	138	180	62

Figure S55. Get High-res Image Gene #6: 'EGFR MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

'PIK3R1 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.612 (Fisher's exact test), Q value = 1

Table S71. Gene #7: 'PIK3R1 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	9	10	8
PIK3R1 MUTATED	2	1	0
PIK3R1 WILD-TYPE	7	9	8

'PIK3R1 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.58 (Fisher's exact test), Q value = 1

Table S72. Gene #7: 'PIK3R1 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	7	7	7	6
PIK3R1 MUTATED	2	0	1	0
PIK3R1 WILD-TYPE	5	7	6	6

'PIK3R1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.019 (Fisher's exact test), Q value = 0.21

Table S73. Gene #7: 'PIK3R1 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	169	120	221
PIK3R1 MUTATED	2	5	15
PIK3R1 WILD-TYPE	167	115	206

Figure S56. Get High-res Image Gene #7: 'PIK3R1 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

'PIK3R1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.00223 (Fisher's exact test), Q value = 0.042

Table S74. Gene #7: 'PIK3R1 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	222	81	168	42
PIK3R1 MUTATED	3	5	14	0
PIK3R1 WILD-TYPE	219	76	154	42

Figure S57. Get High-res Image Gene #7: 'PIK3R1 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

'PIK3R1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.817 (Fisher's exact test), Q value = 1

Table S75. Gene #7: 'PIK3R1 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	52	62	68	74
PIK3R1 MUTATED	3	2	5	4
PIK3R1 WILD-TYPE	49	60	63	70

'PIK3R1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.937 (Fisher's exact test), Q value = 1

Table S76. Gene #7: 'PIK3R1 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	67	131	58
PIK3R1 MUTATED	3	8	3
PIK3R1 WILD-TYPE	64	123	55

'PIK3R1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.124 (Fisher's exact test), Q value = 0.66

Table S77. Gene #7: 'PIK3R1 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	132	109	109	133	30
PIK3R1 MUTATED	2	6	8	4	2
PIK3R1 WILD-TYPE	130	103	101	129	28

'PIK3R1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0373 (Fisher's exact test), Q value = 0.33

Table S78. Gene #7: 'PIK3R1 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	134	71	36	66	91	41	74
PIK3R1 MUTATED	3	2	1	0	9	3	4
PIK3R1 WILD-TYPE	131	69	35	66	82	38	70

Figure S58. Get High-res Image Gene #7: 'PIK3R1 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'PIK3R1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.0862 (Fisher's exact test), Q value = 0.53

Table S79. Gene #7: 'PIK3R1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
PIK3R1 MUTATED	6	3	5	8
PIK3R1 WILD-TYPE	130	104	178	75

'PIK3R1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.582 (Fisher's exact test), Q value = 1

Table S80. Gene #7: 'PIK3R1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
PIK3R1 MUTATED	12	7	3
PIK3R1 WILD-TYPE	210	177	100

'PIK3R1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.962 (Fisher's exact test), Q value = 1

Table S81. Gene #7: 'PIK3R1 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
PIK3R1 MUTATED	9	7	6
PIK3R1 WILD-TYPE	175	155	153

'PIK3R1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.629 (Fisher's exact test), Q value = 1

Table S82. Gene #7: 'PIK3R1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
PIK3R1 MUTATED	3	8	9	2
PIK3R1 WILD-TYPE	87	130	179	87

'IDH2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.00149 (Fisher's exact test), Q value = 0.029

Table S83. Gene #8: 'IDH2 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	169	120	221
IDH2 MUTATED	1	3	16
IDH2 WILD-TYPE	168	117	205

Figure S59. Get High-res Image Gene #8: 'IDH2 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

'IDH2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.00037 (Fisher's exact test), Q value = 0.009

Table S84. Gene #8: 'IDH2 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	222	81	168	42
IDH2 MUTATED	3	0	13	4
IDH2 WILD-TYPE	219	81	155	38

Figure S60. Get High-res Image Gene #8: 'IDH2 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

'IDH2 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.506 (Fisher's exact test), Q value = 1

Table S85. Gene #8: 'IDH2 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	52	62	68	74
IDH2 MUTATED	1	4	2	5
IDH2 WILD-TYPE	51	58	66	69

'IDH2 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.18 (Fisher's exact test), Q value = 0.81

Table S86. Gene #8: 'IDH2 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	67	131	58
IDH2 MUTATED	1	6	5
IDH2 WILD-TYPE	66	125	53

'IDH2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.00766 (Fisher's exact test), Q value = 0.11

Table S87. Gene #8: 'IDH2 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	132	109	109	133	30
IDH2 MUTATED	1	1	8	9	1
IDH2 WILD-TYPE	131	108	101	124	29

Figure S61. Get High-res Image Gene #8: 'IDH2 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

'IDH2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00016 (Fisher's exact test), Q value = 0.0042

Table S88. Gene #8: 'IDH2 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	134	71	36	66	91	41	74
IDH2 MUTATED	1	0	4	1	6	0	8
IDH2 WILD-TYPE	133	71	32	65	85	41	66

Figure S62. Get High-res Image Gene #8: 'IDH2 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'IDH2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.0094 (Fisher's exact test), Q value = 0.13

Table S89. Gene #8: 'IDH2 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
IDH2 MUTATED	3	0	12	5
IDH2 WILD-TYPE	133	107	171	78

Figure S63. Get High-res Image Gene #8: 'IDH2 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

'IDH2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.00076 (Fisher's exact test), Q value = 0.017

Table S90. Gene #8: 'IDH2 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
IDH2 MUTATED	5	15	0
IDH2 WILD-TYPE	217	169	103

Figure S64. Get High-res Image Gene #8: 'IDH2 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

'IDH2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.00291 (Fisher's exact test), Q value = 0.053

Table S91. Gene #8: 'IDH2 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
IDH2 MUTATED	1	8	11
IDH2 WILD-TYPE	183	154	148

Figure S65. Get High-res Image Gene #8: 'IDH2 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

'IDH2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.0463 (Fisher's exact test), Q value = 0.38

Table S92. Gene #8: 'IDH2 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
IDH2 MUTATED	2	6	12	0
IDH2 WILD-TYPE	88	132	176	89

Figure S66. Get High-res Image Gene #8: 'IDH2 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

'NF1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.00124 (Fisher's exact test), Q value = 0.025

Table S93. Gene #9: 'NF1 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	169	120	221
NF1 MUTATED	6	17	10
NF1 WILD-TYPE	163	103	211

Figure S67. Get High-res Image Gene #9: 'NF1 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

'NF1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1e-05 (Fisher's exact test), Q value = 0.00032

Table S94. Gene #9: 'NF1 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	222	81	168	42
NF1 MUTATED	1	19	8	5
NF1 WILD-TYPE	221	62	160	37

Figure S68. Get High-res Image Gene #9: 'NF1 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

'NF1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.0533 (Fisher's exact test), Q value = 0.42

Table S95. Gene #9: 'NF1 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	52	62	68	74
NF1 MUTATED	1	9	3	4
NF1 WILD-TYPE	51	53	65	70

'NF1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.175 (Fisher's exact test), Q value = 0.8

Table S96. Gene #9: 'NF1 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	67	131	58
NF1 MUTATED	4	12	1
NF1 WILD-TYPE	63	119	57

'NF1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1e-05 (Fisher's exact test), Q value = 0.00032

Table S97. Gene #9: 'NF1 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	132	109	109	133	30
NF1 MUTATED	1	20	6	4	2
NF1 WILD-TYPE	131	89	103	129	28

Figure S69. Get High-res Image Gene #9: 'NF1 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

'NF1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 1e-05 (Fisher's exact test), Q value = 0.00032

Table S98. Gene #9: 'NF1 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	134	71	36	66	91	41	74
NF1 MUTATED	1	16	1	3	6	4	2
NF1 WILD-TYPE	133	55	35	63	85	37	72

Figure S70. Get High-res Image Gene #9: 'NF1 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'NF1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.335 (Fisher's exact test), Q value = 0.95

Table S99. Gene #9: 'NF1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
NF1 MUTATED	9	11	9	4
NF1 WILD-TYPE	127	96	174	79

'NF1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.00011 (Fisher's exact test), Q value = 0.003

Table S100. Gene #9: 'NF1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
NF1 MUTATED	10	6	17
NF1 WILD-TYPE	212	178	86

Figure S71. Get High-res Image Gene #9: 'NF1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

'NF1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.00503 (Fisher's exact test), Q value = 0.078

Table S101. Gene #9: 'NF1 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
NF1 MUTATED	21	6	6
NF1 WILD-TYPE	163	156	153

Figure S72. Get High-res Image Gene #9: 'NF1 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

'NF1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1e-05 (Fisher's exact test), Q value = 0.00032

Table S102. Gene #9: 'NF1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
NF1 MUTATED	1	6	7	19
NF1 WILD-TYPE	89	132	181	70

Figure S73. Get High-res Image Gene #9: 'NF1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

'PTEN MUTATION STATUS' versus 'CN_CNMF'

P value = 1e-05 (Fisher's exact test), Q value = 0.00032

Table S103. Gene #10: 'PTEN MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	169	120	221
PTEN MUTATED	3	20	1
PTEN WILD-TYPE	166	100	220

Figure S74. Get High-res Image Gene #10: 'PTEN MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

'PTEN MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1e-05 (Fisher's exact test), Q value = 0.00032

Table S104. Gene #10: 'PTEN MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	222	81	168	42
PTEN MUTATED	3	18	1	2
PTEN WILD-TYPE	219	63	167	40

Figure S75. Get High-res Image Gene #10: 'PTEN MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

'PTEN MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.00047 (Fisher's exact test), Q value = 0.011

Table S105. Gene #10: 'PTEN MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	52	62	68	74
PTEN MUTATED	1	8	1	0
PTEN WILD-TYPE	51	54	67	74

Figure S76. Get High-res Image Gene #10: 'PTEN MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

'PTEN MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.00521 (Fisher's exact test), Q value = 0.08

Table S106. Gene #10: 'PTEN MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	67	131	58
PTEN MUTATED	0	10	0
PTEN WILD-TYPE	67	121	58

Figure S77. Get High-res Image Gene #10: 'PTEN MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

'PTEN MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1e-05 (Fisher's exact test), Q value = 0.00032

Table S107. Gene #10: 'PTEN MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	132	109	109	133	30
PTEN MUTATED	3	19	1	0	1
PTEN WILD-TYPE	129	90	108	133	29

Figure S78. Get High-res Image Gene #10: 'PTEN MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

'PTEN MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 1e-05 (Fisher's exact test), Q value = 0.00032

Table S108. Gene #10: 'PTEN MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	134	71	36	66	91	41	74
PTEN MUTATED	2	18	0	1	1	2	0
PTEN WILD-TYPE	132	53	36	65	90	39	74

Figure S79. Get High-res Image Gene #10: 'PTEN MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'PTEN MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.00357 (Fisher's exact test), Q value = 0.06

Table S109. Gene #10: 'PTEN MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
PTEN MUTATED	12	8	3	1
PTEN WILD-TYPE	124	99	180	82

Figure S80. Get High-res Image Gene #10: 'PTEN MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

'PTEN MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 1e-05 (Fisher's exact test), Q value = 0.00032

Table S110. Gene #10: 'PTEN MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
PTEN MUTATED	6	1	17
PTEN WILD-TYPE	216	183	86

Figure S81. Get High-res Image Gene #10: 'PTEN MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

'PTEN MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 3e-05 (Fisher's exact test), Q value = 0.00089

Table S111. Gene #10: 'PTEN MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
PTEN MUTATED	20	2	2
PTEN WILD-TYPE	164	160	157

Figure S82. Get High-res Image Gene #10: 'PTEN MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

'PTEN MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1e-05 (Fisher's exact test), Q value = 0.00032

Table S112. Gene #10: 'PTEN MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
PTEN MUTATED	3	3	1	17
PTEN WILD-TYPE	87	135	187	72

Figure S83. Get High-res Image Gene #10: 'PTEN MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

'FUBP1 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.0233 (Fisher's exact test), Q value = 0.25

Table S113. Gene #11: 'FUBP1 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	9	10	8
FUBP1 MUTATED	0	4	0
FUBP1 WILD-TYPE	9	6	8

Figure S84. Get High-res Image Gene #11: 'FUBP1 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

'FUBP1 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.00689 (Fisher's exact test), Q value = 0.1

Table S114. Gene #11: 'FUBP1 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	7	7	7	6
FUBP1 MUTATED	0	0	4	0
FUBP1 WILD-TYPE	7	7	3	6

Figure S85. Get High-res Image Gene #11: 'FUBP1 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

'FUBP1 MUTATION STATUS' versus 'CN_CNMF'

P value = 1e-05 (Fisher's exact test), Q value = 0.00032

Table S115. Gene #11: 'FUBP1 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	169	120	221
FUBP1 MUTATED	0	1	46
FUBP1 WILD-TYPE	169	119	175

Figure S86. Get High-res Image Gene #11: 'FUBP1 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

'FUBP1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1e-05 (Fisher's exact test), Q value = 0.00032

Table S116. Gene #11: 'FUBP1 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	222	81	168	42
FUBP1 MUTATED	0	1	46	0
FUBP1 WILD-TYPE	222	80	122	42

Figure S87. Get High-res Image Gene #11: 'FUBP1 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

'FUBP1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.018 (Fisher's exact test), Q value = 0.21

Table S117. Gene #11: 'FUBP1 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	52	62	68	74
FUBP1 MUTATED	1	2	10	9
FUBP1 WILD-TYPE	51	60	58	65

Figure S88. Get High-res Image Gene #11: 'FUBP1 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

'FUBP1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.804 (Fisher's exact test), Q value = 1

Table S118. Gene #11: 'FUBP1 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	67	131	58
FUBP1 MUTATED	7	11	4
FUBP1 WILD-TYPE	60	120	54

'FUBP1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1e-05 (Fisher's exact test), Q value = 0.00032

Table S119. Gene #11: 'FUBP1 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	132	109	109	133	30
FUBP1 MUTATED	0	1	32	11	3
FUBP1 WILD-TYPE	132	108	77	122	27

Figure S89. Get High-res Image Gene #11: 'FUBP1 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

'FUBP1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 1e-05 (Fisher's exact test), Q value = 0.00032

Table S120. Gene #11: 'FUBP1 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	134	71	36	66	91	41	74
FUBP1 MUTATED	0	0	12	0	22	1	12
FUBP1 WILD-TYPE	134	71	24	66	69	40	62

Figure S90. Get High-res Image Gene #11: 'FUBP1 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'FUBP1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1e-05 (Fisher's exact test), Q value = 0.00032

Table S121. Gene #11: 'FUBP1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
FUBP1 MUTATED	6	1	22	18
FUBP1 WILD-TYPE	130	106	161	65

Figure S91. Get High-res Image Gene #11: 'FUBP1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

'FUBP1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.00102 (Fisher's exact test), Q value = 0.022

Table S122. Gene #11: 'FUBP1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
FUBP1 MUTATED	24	22	1
FUBP1 WILD-TYPE	198	162	102

Figure S92. Get High-res Image Gene #11: 'FUBP1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

'FUBP1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.00735 (Fisher's exact test), Q value = 0.1

Table S123. Gene #11: 'FUBP1 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
FUBP1 MUTATED	8	22	17
FUBP1 WILD-TYPE	176	140	142

Figure S93. Get High-res Image Gene #11: 'FUBP1 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

'FUBP1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1e-05 (Fisher's exact test), Q value = 0.00032

Table S124. Gene #11: 'FUBP1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
FUBP1 MUTATED	0	23	24	0
FUBP1 WILD-TYPE	90	115	164	89

Figure S94. Get High-res Image Gene #11: 'FUBP1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

'ARID1A MUTATION STATUS' versus 'CN_CNMF'

P value = 0.693 (Fisher's exact test), Q value = 1

Table S125. Gene #12: 'ARID1A MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	169	120	221
ARID1A MUTATED	6	3	10
ARID1A WILD-TYPE	163	117	211

'ARID1A MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0791 (Fisher's exact test), Q value = 0.51

Table S126. Gene #12: 'ARID1A MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	222	81	168	42
ARID1A MUTATED	6	2	12	0
ARID1A WILD-TYPE	216	79	156	42

'ARID1A MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.317 (Fisher's exact test), Q value = 0.95

Table S127. Gene #12: 'ARID1A MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	52	62	68	74
ARID1A MUTATED	2	1	6	4
ARID1A WILD-TYPE	50	61	62	70

'ARID1A MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.7 (Fisher's exact test), Q value = 1

Table S128. Gene #12: 'ARID1A MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	67	131	58
ARID1A MUTATED	2	8	3
ARID1A WILD-TYPE	65	123	55

'ARID1A MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0324 (Fisher's exact test), Q value = 0.3

Table S129. Gene #12: 'ARID1A MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	132	109	109	133	30
ARID1A MUTATED	4	1	10	5	0
ARID1A WILD-TYPE	128	108	99	128	30

Figure S95. Get High-res Image Gene #12: 'ARID1A MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

'ARID1A MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.142 (Fisher's exact test), Q value = 0.73

Table S130. Gene #12: 'ARID1A MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	134	71	36	66	91	41	74
ARID1A MUTATED	4	0	3	2	7	1	3
ARID1A WILD-TYPE	130	71	33	64	84	40	71

'ARID1A MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.314 (Fisher's exact test), Q value = 0.94

Table S131. Gene #12: 'ARID1A MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
ARID1A MUTATED	5	2	7	6
ARID1A WILD-TYPE	131	105	176	77

'ARID1A MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.606 (Fisher's exact test), Q value = 1

Table S132. Gene #12: 'ARID1A MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
ARID1A MUTATED	10	8	2
ARID1A WILD-TYPE	212	176	101

'ARID1A MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.0837 (Fisher's exact test), Q value = 0.52

Table S133. Gene #12: 'ARID1A MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
ARID1A MUTATED	3	10	7
ARID1A WILD-TYPE	181	152	152

'ARID1A MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.0305 (Fisher's exact test), Q value = 0.29

Table S134. Gene #12: 'ARID1A MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
ARID1A MUTATED	1	11	7	1
ARID1A WILD-TYPE	89	127	181	88

Figure S96. Get High-res Image Gene #12: 'ARID1A MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

'PIK3CA MUTATION STATUS' versus 'CN_CNMF'

P value = 8e-05 (Fisher's exact test), Q value = 0.0023

Table S135. Gene #13: 'PIK3CA MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	169	120	221
PIK3CA MUTATED	3	13	28
PIK3CA WILD-TYPE	166	107	193

Figure S97. Get High-res Image Gene #13: 'PIK3CA MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

'PIK3CA MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1e-05 (Fisher's exact test), Q value = 0.00032

Table S136. Gene #13: 'PIK3CA MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	222	81	168	42
PIK3CA MUTATED	5	11	25	3
PIK3CA WILD-TYPE	217	70	143	39

Figure S98. Get High-res Image Gene #13: 'PIK3CA MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

'PIK3CA MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.686 (Fisher's exact test), Q value = 1

Table S137. Gene #13: 'PIK3CA MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	52	62	68	74
PIK3CA MUTATED	3	7	5	8
PIK3CA WILD-TYPE	49	55	63	66

'PIK3CA MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.881 (Fisher's exact test), Q value = 1

Table S138. Gene #13: 'PIK3CA MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	67	131	58
PIK3CA MUTATED	7	11	5
PIK3CA WILD-TYPE	60	120	53

'PIK3CA MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.00107 (Fisher's exact test), Q value = 0.022

Table S139. Gene #13: 'PIK3CA MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	132	109	109	133	30
PIK3CA MUTATED	2	14	15	10	3
PIK3CA WILD-TYPE	130	95	94	123	27

Figure S99. Get High-res Image Gene #13: 'PIK3CA MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

'PIK3CA MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 3e-05 (Fisher's exact test), Q value = 0.00089

Table S140. Gene #13: 'PIK3CA MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	134	71	36	66	91	41	74
PIK3CA MUTATED	1	11	2	2	15	4	9
PIK3CA WILD-TYPE	133	60	34	64	76	37	65

Figure S100. Get High-res Image Gene #13: 'PIK3CA MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'PIK3CA MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.0097 (Fisher's exact test), Q value = 0.13

Table S141. Gene #13: 'PIK3CA MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
PIK3CA MUTATED	5	14	13	12
PIK3CA WILD-TYPE	131	93	170	71

Figure S101. Get High-res Image Gene #13: 'PIK3CA MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

'PIK3CA MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0395 (Fisher's exact test), Q value = 0.35

Table S142. Gene #13: 'PIK3CA MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
PIK3CA MUTATED	13	16	15
PIK3CA WILD-TYPE	209	168	88

Figure S102. Get High-res Image Gene #13: 'PIK3CA MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

'PIK3CA MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.332 (Fisher's exact test), Q value = 0.95

Table S143. Gene #13: 'PIK3CA MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
PIK3CA MUTATED	17	10	17
PIK3CA WILD-TYPE	167	152	142

'PIK3CA MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.00103 (Fisher's exact test), Q value = 0.022

Table S144. Gene #13: 'PIK3CA MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
PIK3CA MUTATED	0	15	17	12
PIK3CA WILD-TYPE	90	123	171	77

Figure S103. Get High-res Image Gene #13: 'PIK3CA MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

'STK19 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.421 (Fisher's exact test), Q value = 1

Table S145. Gene #14: 'STK19 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	169	120	221
STK19 MUTATED	3	4	3
STK19 WILD-TYPE	166	116	218

'STK19 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.111 (Fisher's exact test), Q value = 0.63

Table S146. Gene #14: 'STK19 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	222	81	168	42
STK19 MUTATED	4	3	1	2
STK19 WILD-TYPE	218	78	167	40

'STK19 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.0754 (Fisher's exact test), Q value = 0.51

Table S147. Gene #14: 'STK19 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	52	62	68	74
STK19 MUTATED	4	0	1	2
STK19 WILD-TYPE	48	62	67	72

'STK19 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.463 (Fisher's exact test), Q value = 1

Table S148. Gene #14: 'STK19 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	67	131	58
STK19 MUTATED	3	2	2
STK19 WILD-TYPE	64	129	56

'STK19 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.298 (Fisher's exact test), Q value = 0.93

Table S149. Gene #14: 'STK19 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	132	109	109	133	30
STK19 MUTATED	2	3	0	4	1
STK19 WILD-TYPE	130	106	109	129	29

'STK19 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.717 (Fisher's exact test), Q value = 1

Table S150. Gene #14: 'STK19 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	134	71	36	66	91	41	74
STK19 MUTATED	2	2	0	3	1	1	1
STK19 WILD-TYPE	132	69	36	63	90	40	73

'STK19 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.167 (Fisher's exact test), Q value = 0.78

Table S151. Gene #14: 'STK19 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
STK19 MUTATED	1	4	5	0
STK19 WILD-TYPE	135	103	178	83

'STK19 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.543 (Fisher's exact test), Q value = 1

Table S152. Gene #14: 'STK19 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
STK19 MUTATED	3	4	3
STK19 WILD-TYPE	219	180	100

'STK19 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.923 (Fisher's exact test), Q value = 1

Table S153. Gene #14: 'STK19 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
STK19 MUTATED	3	4	3
STK19 WILD-TYPE	181	158	156

'STK19 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.842 (Fisher's exact test), Q value = 1

Table S154. Gene #14: 'STK19 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
STK19 MUTATED	1	2	5	2
STK19 WILD-TYPE	89	136	183	87

'NIPBL MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0375 (Fisher's exact test), Q value = 0.33

Table S155. Gene #15: 'NIPBL MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	169	120	221
NIPBL MUTATED	2	3	13
NIPBL WILD-TYPE	167	117	208

Figure S104. Get High-res Image Gene #15: 'NIPBL MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

'NIPBL MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.00069 (Fisher's exact test), Q value = 0.015

Table S156. Gene #15: 'NIPBL MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	222	81	168	42
NIPBL MUTATED	2	2	14	0
NIPBL WILD-TYPE	220	79	154	42

Figure S105. Get High-res Image Gene #15: 'NIPBL MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

'NIPBL MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.523 (Fisher's exact test), Q value = 1

Table S157. Gene #15: 'NIPBL MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	52	62	68	74
NIPBL MUTATED	0	1	3	1
NIPBL WILD-TYPE	52	61	65	73

'NIPBL MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.517 (Fisher's exact test), Q value = 1

Table S158. Gene #15: 'NIPBL MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	67	131	58
NIPBL MUTATED	1	4	0
NIPBL WILD-TYPE	66	127	58

'NIPBL MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.00394 (Fisher's exact test), Q value = 0.065

Table S159. Gene #15: 'NIPBL MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	132	109	109	133	30
NIPBL MUTATED	1	3	10	2	2
NIPBL WILD-TYPE	131	106	99	131	28

Figure S106. Get High-res Image Gene #15: 'NIPBL MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

'NIPBL MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00489 (Fisher's exact test), Q value = 0.077

Table S160. Gene #15: 'NIPBL MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	134	71	36	66	91	41	74
NIPBL MUTATED	2	1	2	0	10	1	2
NIPBL WILD-TYPE	132	70	34	66	81	40	72

Figure S107. Get High-res Image Gene #15: 'NIPBL MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'NIPBL MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.451 (Fisher's exact test), Q value = 1

Table S161. Gene #15: 'NIPBL MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
NIPBL MUTATED	5	4	4	5
NIPBL WILD-TYPE	131	103	179	78

'NIPBL MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.173 (Fisher's exact test), Q value = 0.8

Table S162. Gene #15: 'NIPBL MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
NIPBL MUTATED	12	4	2
NIPBL WILD-TYPE	210	180	101

'NIPBL MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.0115 (Fisher's exact test), Q value = 0.15

Table S163. Gene #15: 'NIPBL MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
NIPBL MUTATED	3	12	3
NIPBL WILD-TYPE	181	150	156

Figure S108. Get High-res Image Gene #15: 'NIPBL MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

'NIPBL MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.0595 (Fisher's exact test), Q value = 0.44

Table S164. Gene #15: 'NIPBL MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
NIPBL MUTATED	3	10	4	1
NIPBL WILD-TYPE	87	128	184	88

'CREBZF MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0515 (Fisher's exact test), Q value = 0.42

Table S165. Gene #16: 'CREBZF MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	169	120	221
CREBZF MUTATED	0	1	6
CREBZF WILD-TYPE	169	119	215

'CREBZF MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.00798 (Fisher's exact test), Q value = 0.11

Table S166. Gene #16: 'CREBZF MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	222	81	168	42
CREBZF MUTATED	0	0	6	1
CREBZF WILD-TYPE	222	81	162	41

Figure S109. Get High-res Image Gene #16: 'CREBZF MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

'CREBZF MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.0852 (Fisher's exact test), Q value = 0.53

Table S167. Gene #16: 'CREBZF MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	52	62	68	74
CREBZF MUTATED	0	1	0	4
CREBZF WILD-TYPE	52	61	68	70

'CREBZF MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.00499 (Fisher's exact test), Q value = 0.078

Table S168. Gene #16: 'CREBZF MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	67	131	58
CREBZF MUTATED	1	0	4
CREBZF WILD-TYPE	66	131	54

Figure S110. Get High-res Image Gene #16: 'CREBZF MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

'CREBZF MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.28 (Fisher's exact test), Q value = 0.9

Table S169. Gene #16: 'CREBZF MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	132	109	109	133	30
CREBZF MUTATED	0	1	2	4	0
CREBZF WILD-TYPE	132	108	107	129	30

'CREBZF MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0224 (Fisher's exact test), Q value = 0.24

Table S170. Gene #16: 'CREBZF MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	134	71	36	66	91	41	74
CREBZF MUTATED	0	1	2	1	0	0	3
CREBZF WILD-TYPE	134	70	34	65	91	41	71

Figure S111. Get High-res Image Gene #16: 'CREBZF MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'CREBZF MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.203 (Fisher's exact test), Q value = 0.85

Table S171. Gene #16: 'CREBZF MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
CREBZF MUTATED	0	1	5	1
CREBZF WILD-TYPE	136	106	178	82

'CREBZF MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0136 (Fisher's exact test), Q value = 0.17

Table S172. Gene #16: 'CREBZF MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
CREBZF MUTATED	0	6	1
CREBZF WILD-TYPE	222	178	102

Figure S112. Get High-res Image Gene #16: 'CREBZF MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

'CREBZF MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.115 (Fisher's exact test), Q value = 0.64

Table S173. Gene #16: 'CREBZF MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
CREBZF MUTATED	1	1	5
CREBZF WILD-TYPE	183	161	154

'CREBZF MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.0532 (Fisher's exact test), Q value = 0.42

Table S174. Gene #16: 'CREBZF MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
CREBZF MUTATED	0	0	6	1
CREBZF WILD-TYPE	90	138	182	88

'TCF12 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.674 (Fisher's exact test), Q value = 1

Table S175. Gene #17: 'TCF12 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	169	120	221
TCF12 MUTATED	5	2	8
TCF12 WILD-TYPE	164	118	213

'TCF12 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.582 (Fisher's exact test), Q value = 1

Table S176. Gene #17: 'TCF12 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	222	81	168	42
TCF12 MUTATED	6	1	6	2
TCF12 WILD-TYPE	216	80	162	40

'TCF12 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.351 (Fisher's exact test), Q value = 0.96

Table S177. Gene #17: 'TCF12 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	52	62	68	74
TCF12 MUTATED	1	1	5	2
TCF12 WILD-TYPE	51	61	63	72

'TCF12 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.608 (Fisher's exact test), Q value = 1

Table S178. Gene #17: 'TCF12 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	67	131	58
TCF12 MUTATED	1	6	2
TCF12 WILD-TYPE	66	125	56

'TCF12 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.816 (Fisher's exact test), Q value = 1

Table S179. Gene #17: 'TCF12 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	132	109	109	133	30
TCF12 MUTATED	4	3	5	3	0
TCF12 WILD-TYPE	128	106	104	130	30

'TCF12 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.476 (Fisher's exact test), Q value = 1

Table S180. Gene #17: 'TCF12 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	134	71	36	66	91	41	74
TCF12 MUTATED	4	1	3	2	2	2	1
TCF12 WILD-TYPE	130	70	33	64	89	39	73

'TCF12 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.697 (Fisher's exact test), Q value = 1

Table S181. Gene #17: 'TCF12 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
TCF12 MUTATED	4	2	5	4
TCF12 WILD-TYPE	132	105	178	79

'TCF12 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.515 (Fisher's exact test), Q value = 1

Table S182. Gene #17: 'TCF12 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
TCF12 MUTATED	8	6	1
TCF12 WILD-TYPE	214	178	102

'TCF12 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S183. Gene #17: 'TCF12 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
TCF12 MUTATED	5	5	5
TCF12 WILD-TYPE	179	157	154

'TCF12 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.514 (Fisher's exact test), Q value = 1

Table S184. Gene #17: 'TCF12 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
TCF12 MUTATED	4	3	7	1
TCF12 WILD-TYPE	86	135	181	88

'TRERF1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.246 (Fisher's exact test), Q value = 0.88

Table S185. Gene #18: 'TRERF1 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	169	120	221
TRERF1 MUTATED	4	1	1
TRERF1 WILD-TYPE	165	119	220

'TRERF1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.125 (Fisher's exact test), Q value = 0.67

Table S186. Gene #18: 'TRERF1 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	222	81	168	42
TRERF1 MUTATED	3	2	0	1
TRERF1 WILD-TYPE	219	79	168	41

'TRERF1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.782 (Fisher's exact test), Q value = 1

Table S187. Gene #18: 'TRERF1 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	52	62	68	74
TRERF1 MUTATED	1	0	1	2
TRERF1 WILD-TYPE	51	62	67	72

'TRERF1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.347 (Fisher's exact test), Q value = 0.95

Table S188. Gene #18: 'TRERF1 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	67	131	58
TRERF1 MUTATED	1	1	2
TRERF1 WILD-TYPE	66	130	56

'TRERF1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.392 (Fisher's exact test), Q value = 1

Table S189. Gene #18: 'TRERF1 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	132	109	109	133	30
TRERF1 MUTATED	2	2	0	1	1
TRERF1 WILD-TYPE	130	107	109	132	29

'TRERF1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.577 (Fisher's exact test), Q value = 1

Table S190. Gene #18: 'TRERF1 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	134	71	36	66	91	41	74
TRERF1 MUTATED	3	1	0	1	0	1	0
TRERF1 WILD-TYPE	131	70	36	65	91	40	74

'TRERF1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.391 (Fisher's exact test), Q value = 1

Table S191. Gene #18: 'TRERF1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
TRERF1 MUTATED	1	3	2	0
TRERF1 WILD-TYPE	135	104	181	83

'TRERF1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.758 (Fisher's exact test), Q value = 1

Table S192. Gene #18: 'TRERF1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
TRERF1 MUTATED	2	2	2
TRERF1 WILD-TYPE	220	182	101

'TRERF1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.105 (Fisher's exact test), Q value = 0.61

Table S193. Gene #18: 'TRERF1 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
TRERF1 MUTATED	2	0	4
TRERF1 WILD-TYPE	182	162	155

'TRERF1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.353 (Fisher's exact test), Q value = 0.96

Table S194. Gene #18: 'TRERF1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
TRERF1 MUTATED	1	0	4	1
TRERF1 WILD-TYPE	89	138	184	88

'SRPX MUTATION STATUS' versus 'CN_CNMF'

P value = 0.223 (Fisher's exact test), Q value = 0.86

Table S195. Gene #19: 'SRPX MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	169	120	221
SRPX MUTATED	0	2	2
SRPX WILD-TYPE	169	118	219

'SRPX MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.107 (Fisher's exact test), Q value = 0.62

Table S196. Gene #19: 'SRPX MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	222	81	168	42
SRPX MUTATED	0	2	2	0
SRPX WILD-TYPE	222	79	166	42

'SRPX MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.439 (Fisher's exact test), Q value = 1

Table S197. Gene #19: 'SRPX MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	52	62	68	74
SRPX MUTATED	0	1	2	0
SRPX WILD-TYPE	52	61	66	74

'SRPX MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S198. Gene #19: 'SRPX MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	67	131	58
SRPX MUTATED	1	2	0
SRPX WILD-TYPE	66	129	58

'SRPX MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.209 (Fisher's exact test), Q value = 0.85

Table S199. Gene #19: 'SRPX MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	132	109	109	133	30
SRPX MUTATED	0	2	2	0	0
SRPX WILD-TYPE	132	107	107	133	30

'SRPX MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.142 (Fisher's exact test), Q value = 0.73

Table S200. Gene #19: 'SRPX MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	134	71	36	66	91	41	74
SRPX MUTATED	0	2	1	0	1	0	0
SRPX WILD-TYPE	134	69	35	66	90	41	74

'SRPX MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.273 (Fisher's exact test), Q value = 0.9

Table S201. Gene #19: 'SRPX MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
SRPX MUTATED	2	1	0	1
SRPX WILD-TYPE	134	106	183	82

'SRPX MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.195 (Fisher's exact test), Q value = 0.84

Table S202. Gene #19: 'SRPX MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
SRPX MUTATED	2	0	2
SRPX WILD-TYPE	220	184	101

'SRPX MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.397 (Fisher's exact test), Q value = 1

Table S203. Gene #19: 'SRPX MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
SRPX MUTATED	3	1	0
SRPX WILD-TYPE	181	161	159

'SRPX MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.0622 (Fisher's exact test), Q value = 0.45

Table S204. Gene #19: 'SRPX MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
SRPX MUTATED	0	2	0	2
SRPX WILD-TYPE	90	136	188	87

'SMARCA4 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0107 (Fisher's exact test), Q value = 0.14

Table S205. Gene #20: 'SMARCA4 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	169	120	221
SMARCA4 MUTATED	16	4	6
SMARCA4 WILD-TYPE	153	116	215

Figure S113. Get High-res Image Gene #20: 'SMARCA4 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

'SMARCA4 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.103 (Fisher's exact test), Q value = 0.61

Table S206. Gene #20: 'SMARCA4 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	222	81	168	42
SMARCA4 MUTATED	17	2	7	0
SMARCA4 WILD-TYPE	205	79	161	42

'SMARCA4 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.243 (Fisher's exact test), Q value = 0.88

Table S207. Gene #20: 'SMARCA4 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	52	62	68	74
SMARCA4 MUTATED	0	3	5	4
SMARCA4 WILD-TYPE	52	59	63	70

'SMARCA4 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.795 (Fisher's exact test), Q value = 1

Table S208. Gene #20: 'SMARCA4 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	67	131	58
SMARCA4 MUTATED	2	7	3
SMARCA4 WILD-TYPE	65	124	55

'SMARCA4 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.328 (Fisher's exact test), Q value = 0.95

Table S209. Gene #20: 'SMARCA4 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	132	109	109	133	30
SMARCA4 MUTATED	9	2	7	6	2
SMARCA4 WILD-TYPE	123	107	102	127	28

'SMARCA4 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.453 (Fisher's exact test), Q value = 1

Table S210. Gene #20: 'SMARCA4 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	134	71	36	66	91	41	74
SMARCA4 MUTATED	11	1	2	4	4	2	2
SMARCA4 WILD-TYPE	123	70	34	62	87	39	72

'SMARCA4 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.307 (Fisher's exact test), Q value = 0.93

Table S211. Gene #20: 'SMARCA4 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
SMARCA4 MUTATED	8	2	9	6
SMARCA4 WILD-TYPE	128	105	174	77

'SMARCA4 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.244 (Fisher's exact test), Q value = 0.88

Table S212. Gene #20: 'SMARCA4 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
SMARCA4 MUTATED	14	9	2
SMARCA4 WILD-TYPE	208	175	101

'SMARCA4 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.873 (Fisher's exact test), Q value = 1

Table S213. Gene #20: 'SMARCA4 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
SMARCA4 MUTATED	8	9	8
SMARCA4 WILD-TYPE	176	153	151

'SMARCA4 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.164 (Fisher's exact test), Q value = 0.78

Table S214. Gene #20: 'SMARCA4 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
SMARCA4 MUTATED	7	6	11	1
SMARCA4 WILD-TYPE	83	132	177	88

'EMG1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.796 (Fisher's exact test), Q value = 1

Table S215. Gene #21: 'EMG1 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	169	120	221
EMG1 MUTATED	2	1	4
EMG1 WILD-TYPE	167	119	217

'EMG1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.498 (Fisher's exact test), Q value = 1

Table S216. Gene #21: 'EMG1 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	222	81	168	42
EMG1 MUTATED	3	0	4	0
EMG1 WILD-TYPE	219	81	164	42

'EMG1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.126 (Fisher's exact test), Q value = 0.67

Table S217. Gene #21: 'EMG1 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	52	62	68	74
EMG1 MUTATED	2	0	1	0
EMG1 WILD-TYPE	50	62	67	74

'EMG1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S218. Gene #21: 'EMG1 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	67	131	58
EMG1 MUTATED	1	2	0
EMG1 WILD-TYPE	66	129	58

'EMG1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.254 (Fisher's exact test), Q value = 0.89

Table S219. Gene #21: 'EMG1 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	132	109	109	133	30
EMG1 MUTATED	1	0	3	2	1
EMG1 WILD-TYPE	131	109	106	131	29

'EMG1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.139 (Fisher's exact test), Q value = 0.72

Table S220. Gene #21: 'EMG1 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	134	71	36	66	91	41	74
EMG1 MUTATED	1	0	0	2	4	0	0
EMG1 WILD-TYPE	133	71	36	64	87	41	74

'EMG1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.16 (Fisher's exact test), Q value = 0.78

Table S221. Gene #21: 'EMG1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
EMG1 MUTATED	1	0	3	3
EMG1 WILD-TYPE	135	107	180	80

'EMG1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.288 (Fisher's exact test), Q value = 0.92

Table S222. Gene #21: 'EMG1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
EMG1 MUTATED	5	2	0
EMG1 WILD-TYPE	217	182	103

'EMG1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.896 (Fisher's exact test), Q value = 1

Table S223. Gene #21: 'EMG1 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
EMG1 MUTATED	2	3	2
EMG1 WILD-TYPE	182	159	157

'EMG1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.384 (Fisher's exact test), Q value = 1

Table S224. Gene #21: 'EMG1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
EMG1 MUTATED	1	4	2	0
EMG1 WILD-TYPE	89	134	186	89

'FAM47C MUTATION STATUS' versus 'CN_CNMF'

P value = 0.309 (Fisher's exact test), Q value = 0.93

Table S225. Gene #22: 'FAM47C MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	169	120	221
FAM47C MUTATED	3	5	10
FAM47C WILD-TYPE	166	115	211

'FAM47C MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.818 (Fisher's exact test), Q value = 1

Table S226. Gene #22: 'FAM47C MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	222	81	168	42
FAM47C MUTATED	7	2	7	2
FAM47C WILD-TYPE	215	79	161	40

'FAM47C MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.436 (Fisher's exact test), Q value = 1

Table S227. Gene #22: 'FAM47C MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	52	62	68	74
FAM47C MUTATED	1	1	2	5
FAM47C WILD-TYPE	51	61	66	69

'FAM47C MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.287 (Fisher's exact test), Q value = 0.92

Table S228. Gene #22: 'FAM47C MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	67	131	58
FAM47C MUTATED	1	4	4
FAM47C WILD-TYPE	66	127	54

'FAM47C MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.278 (Fisher's exact test), Q value = 0.9

Table S229. Gene #22: 'FAM47C MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	132	109	109	133	30
FAM47C MUTATED	2	3	5	8	0
FAM47C WILD-TYPE	130	106	104	125	30

'FAM47C MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0118 (Fisher's exact test), Q value = 0.15

Table S230. Gene #22: 'FAM47C MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	134	71	36	66	91	41	74
FAM47C MUTATED	0	2	0	5	5	1	5
FAM47C WILD-TYPE	134	69	36	61	86	40	69

Figure S114. Get High-res Image Gene #22: 'FAM47C MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'FAM47C MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.612 (Fisher's exact test), Q value = 1

Table S231. Gene #22: 'FAM47C MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
FAM47C MUTATED	3	4	9	2
FAM47C WILD-TYPE	133	103	174	81

'FAM47C MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0923 (Fisher's exact test), Q value = 0.56

Table S232. Gene #22: 'FAM47C MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
FAM47C MUTATED	5	11	2
FAM47C WILD-TYPE	217	173	101

'FAM47C MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.00848 (Fisher's exact test), Q value = 0.11

Table S233. Gene #22: 'FAM47C MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
FAM47C MUTATED	3	3	12
FAM47C WILD-TYPE	181	159	147

Figure S115. Get High-res Image Gene #22: 'FAM47C MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

'FAM47C MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.00353 (Fisher's exact test), Q value = 0.06

Table S234. Gene #22: 'FAM47C MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
FAM47C MUTATED	0	3	14	1
FAM47C WILD-TYPE	90	135	174	88

Figure S116. Get High-res Image Gene #22: 'FAM47C MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

'TNRC18 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.774 (Fisher's exact test), Q value = 1

Table S235. Gene #23: 'TNRC18 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	169	120	221
TNRC18 MUTATED	2	3	5
TNRC18 WILD-TYPE	167	117	216

'TNRC18 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.099 (Fisher's exact test), Q value = 0.59

Table S236. Gene #23: 'TNRC18 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	222	81	168	42
TNRC18 MUTATED	4	4	1	1
TNRC18 WILD-TYPE	218	77	167	41

'TNRC18 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.844 (Fisher's exact test), Q value = 1

Table S237. Gene #23: 'TNRC18 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	52	62	68	74
TNRC18 MUTATED	0	1	2	1
TNRC18 WILD-TYPE	52	61	66	73

'TNRC18 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.671 (Fisher's exact test), Q value = 1

Table S238. Gene #23: 'TNRC18 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	67	131	58
TNRC18 MUTATED	0	3	1
TNRC18 WILD-TYPE	67	128	57

'TNRC18 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.131 (Fisher's exact test), Q value = 0.69

Table S239. Gene #23: 'TNRC18 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	132	109	109	133	30
TNRC18 MUTATED	1	4	0	4	1
TNRC18 WILD-TYPE	131	105	109	129	29

'TNRC18 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.401 (Fisher's exact test), Q value = 1

Table S240. Gene #23: 'TNRC18 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	134	71	36	66	91	41	74
TNRC18 MUTATED	2	3	0	2	0	1	2
TNRC18 WILD-TYPE	132	68	36	64	91	40	72

'TNRC18 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.511 (Fisher's exact test), Q value = 1

Table S241. Gene #23: 'TNRC18 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
TNRC18 MUTATED	4	2	4	0
TNRC18 WILD-TYPE	132	105	179	83

'TNRC18 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.182 (Fisher's exact test), Q value = 0.81

Table S242. Gene #23: 'TNRC18 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
TNRC18 MUTATED	2	4	4
TNRC18 WILD-TYPE	220	180	99

'TNRC18 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S243. Gene #23: 'TNRC18 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
TNRC18 MUTATED	3	3	3
TNRC18 WILD-TYPE	181	159	156

'TNRC18 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.345 (Fisher's exact test), Q value = 0.95

Table S244. Gene #23: 'TNRC18 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
TNRC18 MUTATED	0	2	4	3
TNRC18 WILD-TYPE	90	136	184	86

'DNMT3A MUTATION STATUS' versus 'CN_CNMF'

P value = 0.662 (Fisher's exact test), Q value = 1

Table S245. Gene #24: 'DNMT3A MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	169	120	221
DNMT3A MUTATED	4	3	3
DNMT3A WILD-TYPE	165	117	218

'DNMT3A MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.646 (Fisher's exact test), Q value = 1

Table S246. Gene #24: 'DNMT3A MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	222	81	168	42
DNMT3A MUTATED	4	3	3	0
DNMT3A WILD-TYPE	218	78	165	42

'DNMT3A MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.684 (Fisher's exact test), Q value = 1

Table S247. Gene #24: 'DNMT3A MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	52	62	68	74
DNMT3A MUTATED	1	0	2	2
DNMT3A WILD-TYPE	51	62	66	72

'DNMT3A MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.839 (Fisher's exact test), Q value = 1

Table S248. Gene #24: 'DNMT3A MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	67	131	58
DNMT3A MUTATED	2	2	1
DNMT3A WILD-TYPE	65	129	57

'DNMT3A MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.634 (Fisher's exact test), Q value = 1

Table S249. Gene #24: 'DNMT3A MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	132	109	109	133	30
DNMT3A MUTATED	4	2	3	1	0
DNMT3A WILD-TYPE	128	107	106	132	30

'DNMT3A MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.941 (Fisher's exact test), Q value = 1

Table S250. Gene #24: 'DNMT3A MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	134	71	36	66	91	41	74
DNMT3A MUTATED	3	1	1	2	1	1	1
DNMT3A WILD-TYPE	131	70	35	64	90	40	73

'DNMT3A MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.481 (Fisher's exact test), Q value = 1

Table S251. Gene #24: 'DNMT3A MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
DNMT3A MUTATED	1	2	6	1
DNMT3A WILD-TYPE	135	105	177	82

'DNMT3A MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.045 (Fisher's exact test), Q value = 0.38

Table S252. Gene #24: 'DNMT3A MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
DNMT3A MUTATED	1	5	4
DNMT3A WILD-TYPE	221	179	99

Figure S117. Get High-res Image Gene #24: 'DNMT3A MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

'DNMT3A MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.923 (Fisher's exact test), Q value = 1

Table S253. Gene #24: 'DNMT3A MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
DNMT3A MUTATED	3	4	3
DNMT3A WILD-TYPE	181	158	156

'DNMT3A MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.971 (Fisher's exact test), Q value = 1

Table S254. Gene #24: 'DNMT3A MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
DNMT3A MUTATED	1	3	4	2
DNMT3A WILD-TYPE	89	135	184	87

'HTRA2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0306 (Fisher's exact test), Q value = 0.29

Table S255. Gene #25: 'HTRA2 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	169	120	221
HTRA2 MUTATED	4	1	0
HTRA2 WILD-TYPE	165	119	221

Figure S118. Get High-res Image Gene #25: 'HTRA2 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

'HTRA2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.421 (Fisher's exact test), Q value = 1

Table S256. Gene #25: 'HTRA2 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	222	81	168	42
HTRA2 MUTATED	3	0	1	1
HTRA2 WILD-TYPE	219	81	167	41

'HTRA2 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.379 (Fisher's exact test), Q value = 1

Table S257. Gene #25: 'HTRA2 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	52	62	68	74
HTRA2 MUTATED	2	1	0	1
HTRA2 WILD-TYPE	50	61	68	73

'HTRA2 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S258. Gene #25: 'HTRA2 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	67	131	58
HTRA2 MUTATED	1	2	1
HTRA2 WILD-TYPE	66	129	57

'HTRA2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.952 (Fisher's exact test), Q value = 1

Table S259. Gene #25: 'HTRA2 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	132	109	109	133	30
HTRA2 MUTATED	2	1	1	1	0
HTRA2 WILD-TYPE	130	108	108	132	30

'HTRA2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.641 (Fisher's exact test), Q value = 1

Table S260. Gene #25: 'HTRA2 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	134	71	36	66	91	41	74
HTRA2 MUTATED	2	1	1	0	0	0	1
HTRA2 WILD-TYPE	132	70	35	66	91	41	73

'HTRA2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.349 (Fisher's exact test), Q value = 0.96

Table S261. Gene #25: 'HTRA2 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
HTRA2 MUTATED	3	0	1	1
HTRA2 WILD-TYPE	133	107	182	82

'HTRA2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.725 (Fisher's exact test), Q value = 1

Table S262. Gene #25: 'HTRA2 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
HTRA2 MUTATED	3	2	0
HTRA2 WILD-TYPE	219	182	103

'HTRA2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.556 (Fisher's exact test), Q value = 1

Table S263. Gene #25: 'HTRA2 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
HTRA2 MUTATED	2	2	0
HTRA2 WILD-TYPE	182	160	159

'HTRA2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.47 (Fisher's exact test), Q value = 1

Table S264. Gene #25: 'HTRA2 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
HTRA2 MUTATED	2	1	1	0
HTRA2 WILD-TYPE	88	137	187	89

'ZNF709 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.69 (Fisher's exact test), Q value = 1

Table S265. Gene #26: 'ZNF709 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	169	120	221
ZNF709 MUTATED	2	0	2
ZNF709 WILD-TYPE	167	120	219

'ZNF709 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S266. Gene #26: 'ZNF709 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	222	81	168	42
ZNF709 MUTATED	2	0	2	0
ZNF709 WILD-TYPE	220	81	166	42

'ZNF709 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S267. Gene #26: 'ZNF709 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	52	62	68	74
ZNF709 MUTATED	1	1	1	1
ZNF709 WILD-TYPE	51	61	67	73

'ZNF709 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S268. Gene #26: 'ZNF709 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	67	131	58
ZNF709 MUTATED	1	2	1
ZNF709 WILD-TYPE	66	129	57

'ZNF709 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.221 (Fisher's exact test), Q value = 0.86

Table S269. Gene #26: 'ZNF709 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	132	109	109	133	30
ZNF709 MUTATED	1	0	0	2	1
ZNF709 WILD-TYPE	131	109	109	131	29

'ZNF709 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.23 (Fisher's exact test), Q value = 0.86

Table S270. Gene #26: 'ZNF709 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	134	71	36	66	91	41	74
ZNF709 MUTATED	0	0	0	0	2	1	1
ZNF709 WILD-TYPE	134	71	36	66	89	40	73

'ZNF709 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S271. Gene #26: 'ZNF709 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
ZNF709 MUTATED	1	1	2	0
ZNF709 WILD-TYPE	135	106	181	83

'ZNF709 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.681 (Fisher's exact test), Q value = 1

Table S272. Gene #26: 'ZNF709 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
ZNF709 MUTATED	1	2	1
ZNF709 WILD-TYPE	221	182	102

'ZNF709 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.271 (Fisher's exact test), Q value = 0.9

Table S273. Gene #26: 'ZNF709 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
ZNF709 MUTATED	3	0	1
ZNF709 WILD-TYPE	181	162	158

'ZNF709 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S274. Gene #26: 'ZNF709 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
ZNF709 MUTATED	1	1	2	0
ZNF709 WILD-TYPE	89	137	186	89

'RBPJ MUTATION STATUS' versus 'CN_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S275. Gene #27: 'RBPJ MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	169	120	221
RBPJ MUTATED	2	2	3
RBPJ WILD-TYPE	167	118	218

'RBPJ MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.181 (Fisher's exact test), Q value = 0.81

Table S276. Gene #27: 'RBPJ MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	222	81	168	42
RBPJ MUTATED	1	1	5	0
RBPJ WILD-TYPE	221	80	163	42

'RBPJ MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.255 (Fisher's exact test), Q value = 0.89

Table S277. Gene #27: 'RBPJ MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	52	62	68	74
RBPJ MUTATED	0	2	2	0
RBPJ WILD-TYPE	52	60	66	74

'RBPJ MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.181 (Fisher's exact test), Q value = 0.81

Table S278. Gene #27: 'RBPJ MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	67	131	58
RBPJ MUTATED	0	4	0
RBPJ WILD-TYPE	67	127	58

'RBPJ MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.439 (Fisher's exact test), Q value = 1

Table S279. Gene #27: 'RBPJ MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	132	109	109	133	30
RBPJ MUTATED	0	2	3	2	0
RBPJ WILD-TYPE	132	107	106	131	30

'RBPJ MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 8e-05 (Fisher's exact test), Q value = 0.0023

Table S280. Gene #27: 'RBPJ MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	134	71	36	66	91	41	74
RBPJ MUTATED	0	0	4	0	1	2	0
RBPJ WILD-TYPE	134	71	32	66	90	39	74

Figure S119. Get High-res Image Gene #27: 'RBPJ MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'RBPJ MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.33 (Fisher's exact test), Q value = 0.95

Table S281. Gene #27: 'RBPJ MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
RBPJ MUTATED	0	2	4	1
RBPJ WILD-TYPE	136	105	179	82

'RBPJ MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0277 (Fisher's exact test), Q value = 0.27

Table S282. Gene #27: 'RBPJ MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
RBPJ MUTATED	0	5	2
RBPJ WILD-TYPE	222	179	101

Figure S120. Get High-res Image Gene #27: 'RBPJ MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

'RBPJ MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.118 (Fisher's exact test), Q value = 0.64

Table S283. Gene #27: 'RBPJ MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
RBPJ MUTATED	1	1	5
RBPJ WILD-TYPE	183	161	154

'RBPJ MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.445 (Fisher's exact test), Q value = 1

Table S284. Gene #27: 'RBPJ MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
RBPJ MUTATED	0	1	4	2
RBPJ WILD-TYPE	90	137	184	87

'NRAS MUTATION STATUS' versus 'CN_CNMF'

P value = 0.563 (Fisher's exact test), Q value = 1

Table S285. Gene #28: 'NRAS MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	169	120	221
NRAS MUTATED	1	0	3
NRAS WILD-TYPE	168	120	218

'NRAS MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.508 (Fisher's exact test), Q value = 1

Table S286. Gene #28: 'NRAS MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	222	81	168	42
NRAS MUTATED	1	0	3	0
NRAS WILD-TYPE	221	81	165	42

'NRAS MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.417 (Fisher's exact test), Q value = 1

Table S287. Gene #28: 'NRAS MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	132	109	109	133	30
NRAS MUTATED	0	0	2	2	0
NRAS WILD-TYPE	132	109	107	131	30

'NRAS MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.106 (Fisher's exact test), Q value = 0.61

Table S288. Gene #28: 'NRAS MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	134	71	36	66	91	41	74
NRAS MUTATED	0	0	1	1	0	1	1
NRAS WILD-TYPE	134	71	35	65	91	40	73

'NRAS MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.303 (Fisher's exact test), Q value = 0.93

Table S289. Gene #28: 'NRAS MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
NRAS MUTATED	0	0	3	1
NRAS WILD-TYPE	136	107	180	82

'NRAS MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.683 (Fisher's exact test), Q value = 1

Table S290. Gene #28: 'NRAS MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
NRAS MUTATED	1	2	1
NRAS WILD-TYPE	221	182	102

'NRAS MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.336 (Fisher's exact test), Q value = 0.95

Table S291. Gene #28: 'NRAS MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
NRAS MUTATED	0	2	2
NRAS WILD-TYPE	184	160	157

'NRAS MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.761 (Fisher's exact test), Q value = 1

Table S292. Gene #28: 'NRAS MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
NRAS MUTATED	0	2	2	0
NRAS WILD-TYPE	90	136	186	89

'ZNF292 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.115 (Fisher's exact test), Q value = 0.64

Table S293. Gene #29: 'ZNF292 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	169	120	221
ZNF292 MUTATED	2	2	10
ZNF292 WILD-TYPE	167	118	211

'ZNF292 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.205 (Fisher's exact test), Q value = 0.85

Table S294. Gene #29: 'ZNF292 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	222	81	168	42
ZNF292 MUTATED	3	2	8	1
ZNF292 WILD-TYPE	219	79	160	41

'ZNF292 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.284 (Fisher's exact test), Q value = 0.91

Table S295. Gene #29: 'ZNF292 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	52	62	68	74
ZNF292 MUTATED	1	0	3	4
ZNF292 WILD-TYPE	51	62	65	70

'ZNF292 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.451 (Fisher's exact test), Q value = 1

Table S296. Gene #29: 'ZNF292 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	67	131	58
ZNF292 MUTATED	1	4	3
ZNF292 WILD-TYPE	66	127	55

'ZNF292 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.747 (Fisher's exact test), Q value = 1

Table S297. Gene #29: 'ZNF292 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	132	109	109	133	30
ZNF292 MUTATED	3	2	5	4	0
ZNF292 WILD-TYPE	129	107	104	129	30

'ZNF292 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0578 (Fisher's exact test), Q value = 0.43

Table S298. Gene #29: 'ZNF292 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	134	71	36	66	91	41	74
ZNF292 MUTATED	3	0	3	0	2	2	4
ZNF292 WILD-TYPE	131	71	33	66	89	39	70

'ZNF292 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.428 (Fisher's exact test), Q value = 1

Table S299. Gene #29: 'ZNF292 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
ZNF292 MUTATED	2	3	8	1
ZNF292 WILD-TYPE	134	104	175	82

'ZNF292 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.29 (Fisher's exact test), Q value = 0.92

Table S300. Gene #29: 'ZNF292 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
ZNF292 MUTATED	4	8	2
ZNF292 WILD-TYPE	218	176	101

'ZNF292 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.0832 (Fisher's exact test), Q value = 0.52

Table S301. Gene #29: 'ZNF292 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
ZNF292 MUTATED	2	4	8
ZNF292 WILD-TYPE	182	158	151

'ZNF292 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.0544 (Fisher's exact test), Q value = 0.42

Table S302. Gene #29: 'ZNF292 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
ZNF292 MUTATED	0	3	10	1
ZNF292 WILD-TYPE	90	135	178	88

'PTPN11 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.549 (Fisher's exact test), Q value = 1

Table S303. Gene #30: 'PTPN11 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	169	120	221
PTPN11 MUTATED	2	3	2
PTPN11 WILD-TYPE	167	117	219

'PTPN11 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0177 (Fisher's exact test), Q value = 0.21

Table S304. Gene #30: 'PTPN11 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	222	81	168	42
PTPN11 MUTATED	1	4	1	1
PTPN11 WILD-TYPE	221	77	167	41

Figure S121. Get High-res Image Gene #30: 'PTPN11 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

'PTPN11 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.487 (Fisher's exact test), Q value = 1

Table S305. Gene #30: 'PTPN11 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	52	62	68	74
PTPN11 MUTATED	1	2	1	0
PTPN11 WILD-TYPE	51	60	67	74

'PTPN11 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.55 (Fisher's exact test), Q value = 1

Table S306. Gene #30: 'PTPN11 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	67	131	58
PTPN11 MUTATED	2	2	0
PTPN11 WILD-TYPE	65	129	58

'PTPN11 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0516 (Fisher's exact test), Q value = 0.42

Table S307. Gene #30: 'PTPN11 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	132	109	109	133	30
PTPN11 MUTATED	1	5	0	1	0
PTPN11 WILD-TYPE	131	104	109	132	30

'PTPN11 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.225 (Fisher's exact test), Q value = 0.86

Table S308. Gene #30: 'PTPN11 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	134	71	36	66	91	41	74
PTPN11 MUTATED	1	3	0	2	0	0	1
PTPN11 WILD-TYPE	133	68	36	64	91	41	73

'PTPN11 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.222 (Fisher's exact test), Q value = 0.86

Table S309. Gene #30: 'PTPN11 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
PTPN11 MUTATED	3	3	1	0
PTPN11 WILD-TYPE	133	104	182	83

'PTPN11 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.00525 (Fisher's exact test), Q value = 0.08

Table S310. Gene #30: 'PTPN11 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
PTPN11 MUTATED	1	1	5
PTPN11 WILD-TYPE	221	183	98

Figure S122. Get High-res Image Gene #30: 'PTPN11 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

'PTPN11 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.0155 (Fisher's exact test), Q value = 0.19

Table S311. Gene #30: 'PTPN11 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
PTPN11 MUTATED	6	0	1
PTPN11 WILD-TYPE	178	162	158

Figure S123. Get High-res Image Gene #30: 'PTPN11 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

'PTPN11 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.00257 (Fisher's exact test), Q value = 0.047

Table S312. Gene #30: 'PTPN11 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
PTPN11 MUTATED	1	0	1	5
PTPN11 WILD-TYPE	89	138	187	84

Figure S124. Get High-res Image Gene #30: 'PTPN11 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

'GAGE2D MUTATION STATUS' versus 'CN_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S313. Gene #31: 'GAGE2D MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	169	120	221
GAGE2D MUTATED	2	1	2
GAGE2D WILD-TYPE	167	119	219

'GAGE2D MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S314. Gene #31: 'GAGE2D MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	222	81	168	42
GAGE2D MUTATED	2	1	2	0
GAGE2D WILD-TYPE	220	80	166	42

'GAGE2D MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.413 (Fisher's exact test), Q value = 1

Table S315. Gene #31: 'GAGE2D MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	52	62	68	74
GAGE2D MUTATED	0	0	2	2
GAGE2D WILD-TYPE	52	62	66	72

'GAGE2D MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S316. Gene #31: 'GAGE2D MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	67	131	58
GAGE2D MUTATED	1	2	1
GAGE2D WILD-TYPE	66	129	57

'GAGE2D MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.677 (Fisher's exact test), Q value = 1

Table S317. Gene #31: 'GAGE2D MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	132	109	109	133	30
GAGE2D MUTATED	1	1	1	1	1
GAGE2D WILD-TYPE	131	108	108	132	29

'GAGE2D MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.65 (Fisher's exact test), Q value = 1

Table S318. Gene #31: 'GAGE2D MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	134	71	36	66	91	41	74
GAGE2D MUTATED	2	1	0	0	0	0	2
GAGE2D WILD-TYPE	132	70	36	66	91	41	72

'GAGE2D MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.763 (Fisher's exact test), Q value = 1

Table S319. Gene #31: 'GAGE2D MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
GAGE2D MUTATED	1	2	2	0
GAGE2D WILD-TYPE	135	105	181	83

'GAGE2D MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S320. Gene #31: 'GAGE2D MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
GAGE2D MUTATED	2	2	1
GAGE2D WILD-TYPE	220	182	102

'GAGE2D MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.742 (Fisher's exact test), Q value = 1

Table S321. Gene #31: 'GAGE2D MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
GAGE2D MUTATED	1	2	2
GAGE2D WILD-TYPE	183	160	157

'GAGE2D MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.291 (Fisher's exact test), Q value = 0.92

Table S322. Gene #31: 'GAGE2D MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
GAGE2D MUTATED	2	0	2	1
GAGE2D WILD-TYPE	88	138	186	88

'ARID2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.86 (Fisher's exact test), Q value = 1

Table S323. Gene #32: 'ARID2 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	169	120	221
ARID2 MUTATED	4	3	4
ARID2 WILD-TYPE	165	117	217

'ARID2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.267 (Fisher's exact test), Q value = 0.89

Table S324. Gene #32: 'ARID2 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	222	81	168	42
ARID2 MUTATED	5	4	2	0
ARID2 WILD-TYPE	217	77	166	42

'ARID2 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.258 (Fisher's exact test), Q value = 0.89

Table S325. Gene #32: 'ARID2 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	52	62	68	74
ARID2 MUTATED	0	2	2	0
ARID2 WILD-TYPE	52	60	66	74

'ARID2 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.181 (Fisher's exact test), Q value = 0.81

Table S326. Gene #32: 'ARID2 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	67	131	58
ARID2 MUTATED	0	4	0
ARID2 WILD-TYPE	67	127	58

'ARID2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.461 (Fisher's exact test), Q value = 1

Table S327. Gene #32: 'ARID2 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	132	109	109	133	30
ARID2 MUTATED	3	4	2	1	1
ARID2 WILD-TYPE	129	105	107	132	29

'ARID2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.651 (Fisher's exact test), Q value = 1

Table S328. Gene #32: 'ARID2 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	134	71	36	66	91	41	74
ARID2 MUTATED	3	2	1	1	2	2	0
ARID2 WILD-TYPE	131	69	35	65	89	39	74

'ARID2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.603 (Fisher's exact test), Q value = 1

Table S329. Gene #32: 'ARID2 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
ARID2 MUTATED	2	4	3	1
ARID2 WILD-TYPE	134	103	180	82

'ARID2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.345 (Fisher's exact test), Q value = 0.95

Table S330. Gene #32: 'ARID2 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
ARID2 MUTATED	3	3	4
ARID2 WILD-TYPE	219	181	99

'ARID2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.479 (Fisher's exact test), Q value = 1

Table S331. Gene #32: 'ARID2 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
ARID2 MUTATED	3	2	5
ARID2 WILD-TYPE	181	160	154

'ARID2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.461 (Fisher's exact test), Q value = 1

Table S332. Gene #32: 'ARID2 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
ARID2 MUTATED	1	1	5	3
ARID2 WILD-TYPE	89	137	183	86

'ZMIZ1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0512 (Fisher's exact test), Q value = 0.42

Table S333. Gene #33: 'ZMIZ1 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	169	120	221
ZMIZ1 MUTATED	0	3	6
ZMIZ1 WILD-TYPE	169	117	215

'ZMIZ1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.33 (Fisher's exact test), Q value = 0.95

Table S334. Gene #33: 'ZMIZ1 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	222	81	168	42
ZMIZ1 MUTATED	2	2	5	0
ZMIZ1 WILD-TYPE	220	79	163	42

'ZMIZ1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.625 (Fisher's exact test), Q value = 1

Table S335. Gene #33: 'ZMIZ1 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	52	62	68	74
ZMIZ1 MUTATED	0	0	1	2
ZMIZ1 WILD-TYPE	52	62	67	72

'ZMIZ1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.794 (Fisher's exact test), Q value = 1

Table S336. Gene #33: 'ZMIZ1 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	67	131	58
ZMIZ1 MUTATED	1	1	1
ZMIZ1 WILD-TYPE	66	130	57

'ZMIZ1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.526 (Fisher's exact test), Q value = 1

Table S337. Gene #33: 'ZMIZ1 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	132	109	109	133	30
ZMIZ1 MUTATED	1	1	3	3	1
ZMIZ1 WILD-TYPE	131	108	106	130	29

'ZMIZ1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.301 (Fisher's exact test), Q value = 0.93

Table S338. Gene #33: 'ZMIZ1 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	134	71	36	66	91	41	74
ZMIZ1 MUTATED	1	0	0	2	4	1	1
ZMIZ1 WILD-TYPE	133	71	36	64	87	40	73

'ZMIZ1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.476 (Fisher's exact test), Q value = 1

Table S339. Gene #33: 'ZMIZ1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
ZMIZ1 MUTATED	1	2	3	3
ZMIZ1 WILD-TYPE	135	105	180	80

'ZMIZ1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.678 (Fisher's exact test), Q value = 1

Table S340. Gene #33: 'ZMIZ1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
ZMIZ1 MUTATED	5	2	2
ZMIZ1 WILD-TYPE	217	182	101

'ZMIZ1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.0189 (Fisher's exact test), Q value = 0.21

Table S341. Gene #33: 'ZMIZ1 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
ZMIZ1 MUTATED	0	6	3
ZMIZ1 WILD-TYPE	184	156	156

Figure S125. Get High-res Image Gene #33: 'ZMIZ1 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

'ZMIZ1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.42 (Fisher's exact test), Q value = 1

Table S342. Gene #33: 'ZMIZ1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
ZMIZ1 MUTATED	0	4	4	1
ZMIZ1 WILD-TYPE	90	134	184	88

'PDGFRA MUTATION STATUS' versus 'CN_CNMF'

P value = 0.321 (Fisher's exact test), Q value = 0.95

Table S343. Gene #34: 'PDGFRA MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	169	120	221
PDGFRA MUTATED	5	3	2
PDGFRA WILD-TYPE	164	117	219

'PDGFRA MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0636 (Fisher's exact test), Q value = 0.46

Table S344. Gene #34: 'PDGFRA MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	222	81	168	42
PDGFRA MUTATED	3	5	2	0
PDGFRA WILD-TYPE	219	76	166	42

'PDGFRA MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.473 (Fisher's exact test), Q value = 1

Table S345. Gene #34: 'PDGFRA MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	52	62	68	74
PDGFRA MUTATED	1	2	2	0
PDGFRA WILD-TYPE	51	60	66	74

'PDGFRA MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.516 (Fisher's exact test), Q value = 1

Table S346. Gene #34: 'PDGFRA MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	67	131	58
PDGFRA MUTATED	1	4	0
PDGFRA WILD-TYPE	66	127	58

'PDGFRA MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0067 (Fisher's exact test), Q value = 0.099

Table S347. Gene #34: 'PDGFRA MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	132	109	109	133	30
PDGFRA MUTATED	1	7	2	0	0
PDGFRA WILD-TYPE	131	102	107	133	30

Figure S126. Get High-res Image Gene #34: 'PDGFRA MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

'PDGFRA MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00012 (Fisher's exact test), Q value = 0.0032

Table S348. Gene #34: 'PDGFRA MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	134	71	36	66	91	41	74
PDGFRA MUTATED	0	3	1	0	1	5	0
PDGFRA WILD-TYPE	134	68	35	66	90	36	74

Figure S127. Get High-res Image Gene #34: 'PDGFRA MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'PDGFRA MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.00066 (Fisher's exact test), Q value = 0.015

Table S349. Gene #34: 'PDGFRA MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
PDGFRA MUTATED	1	7	0	2
PDGFRA WILD-TYPE	135	100	183	81

Figure S128. Get High-res Image Gene #34: 'PDGFRA MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

'PDGFRA MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.00144 (Fisher's exact test), Q value = 0.029

Table S350. Gene #34: 'PDGFRA MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
PDGFRA MUTATED	2	1	7
PDGFRA WILD-TYPE	220	183	96

Figure S129. Get High-res Image Gene #34: 'PDGFRA MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

'PDGFRA MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.854 (Fisher's exact test), Q value = 1

Table S351. Gene #34: 'PDGFRA MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
PDGFRA MUTATED	3	3	4
PDGFRA WILD-TYPE	181	159	155

'PDGFRA MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.186 (Fisher's exact test), Q value = 0.81

Table S352. Gene #34: 'PDGFRA MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
PDGFRA MUTATED	0	2	4	4
PDGFRA WILD-TYPE	90	136	184	85

'ZNF512B MUTATION STATUS' versus 'CN_CNMF'

P value = 0.453 (Fisher's exact test), Q value = 1

Table S353. Gene #35: 'ZNF512B MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	169	120	221
ZNF512B MUTATED	3	1	1
ZNF512B WILD-TYPE	166	119	220

'ZNF512B MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.819 (Fisher's exact test), Q value = 1

Table S354. Gene #35: 'ZNF512B MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	222	81	168	42
ZNF512B MUTATED	3	1	1	0
ZNF512B WILD-TYPE	219	80	167	42

'ZNF512B MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.625 (Fisher's exact test), Q value = 1

Table S355. Gene #35: 'ZNF512B MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	52	62	68	74
ZNF512B MUTATED	0	0	1	2
ZNF512B WILD-TYPE	52	62	67	72

'ZNF512B MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.61 (Fisher's exact test), Q value = 1

Table S356. Gene #35: 'ZNF512B MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	67	131	58
ZNF512B MUTATED	0	2	1
ZNF512B WILD-TYPE	67	129	57

'ZNF512B MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S357. Gene #35: 'ZNF512B MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	132	109	109	133	30
ZNF512B MUTATED	1	1	1	2	0
ZNF512B WILD-TYPE	131	108	108	131	30

'ZNF512B MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.852 (Fisher's exact test), Q value = 1

Table S358. Gene #35: 'ZNF512B MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	134	71	36	66	91	41	74
ZNF512B MUTATED	1	0	0	1	1	1	1
ZNF512B WILD-TYPE	133	71	36	65	90	40	73

'ZNF512B MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S359. Gene #35: 'ZNF512B MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
ZNF512B MUTATED	1	1	2	1
ZNF512B WILD-TYPE	135	106	181	82

'ZNF512B MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S360. Gene #35: 'ZNF512B MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
ZNF512B MUTATED	2	2	1
ZNF512B WILD-TYPE	220	182	102

'ZNF512B MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.46 (Fisher's exact test), Q value = 1

Table S361. Gene #35: 'ZNF512B MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
ZNF512B MUTATED	1	1	3
ZNF512B WILD-TYPE	183	161	156

'ZNF512B MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.248 (Fisher's exact test), Q value = 0.88

Table S362. Gene #35: 'ZNF512B MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
ZNF512B MUTATED	1	0	4	0
ZNF512B WILD-TYPE	89	138	184	89

'PPL MUTATION STATUS' versus 'CN_CNMF'

P value = 0.772 (Fisher's exact test), Q value = 1

Table S363. Gene #36: 'PPL MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	169	120	221
PPL MUTATED	3	1	2
PPL WILD-TYPE	166	119	219

'PPL MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S364. Gene #36: 'PPL MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	222	81	168	42
PPL MUTATED	3	1	2	0
PPL WILD-TYPE	219	80	166	42

'PPL MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.843 (Fisher's exact test), Q value = 1

Table S365. Gene #36: 'PPL MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	132	109	109	133	30
PPL MUTATED	1	2	2	1	0
PPL WILD-TYPE	131	107	107	132	30

'PPL MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.247 (Fisher's exact test), Q value = 0.88

Table S366. Gene #36: 'PPL MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	134	71	36	66	91	41	74
PPL MUTATED	1	0	0	1	2	2	0
PPL WILD-TYPE	133	71	36	65	89	39	74

'PPL MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.144 (Fisher's exact test), Q value = 0.74

Table S367. Gene #36: 'PPL MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
PPL MUTATED	0	3	3	0
PPL WILD-TYPE	136	104	180	83

'PPL MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.758 (Fisher's exact test), Q value = 1

Table S368. Gene #36: 'PPL MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
PPL MUTATED	2	2	2
PPL WILD-TYPE	220	182	101

'PPL MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.329 (Fisher's exact test), Q value = 0.95

Table S369. Gene #36: 'PPL MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
PPL MUTATED	1	4	1
PPL WILD-TYPE	183	158	158

'PPL MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.726 (Fisher's exact test), Q value = 1

Table S370. Gene #36: 'PPL MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
PPL MUTATED	1	3	2	0
PPL WILD-TYPE	89	135	186	89

'PRX MUTATION STATUS' versus 'CN_CNMF'

P value = 0.113 (Fisher's exact test), Q value = 0.63

Table S371. Gene #37: 'PRX MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	169	120	221
PRX MUTATED	3	5	2
PRX WILD-TYPE	166	115	219

'PRX MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0327 (Fisher's exact test), Q value = 0.3

Table S372. Gene #37: 'PRX MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	222	81	168	42
PRX MUTATED	2	5	2	1
PRX WILD-TYPE	220	76	166	41

Figure S130. Get High-res Image Gene #37: 'PRX MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

'PRX MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.244 (Fisher's exact test), Q value = 0.88

Table S373. Gene #37: 'PRX MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	52	62	68	74
PRX MUTATED	1	0	1	4
PRX WILD-TYPE	51	62	67	70

'PRX MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.0282 (Fisher's exact test), Q value = 0.28

Table S374. Gene #37: 'PRX MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	67	131	58
PRX MUTATED	0	2	4
PRX WILD-TYPE	67	129	54

Figure S131. Get High-res Image Gene #37: 'PRX MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

'PRX MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.386 (Fisher's exact test), Q value = 1

Table S375. Gene #37: 'PRX MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	132	109	109	133	30
PRX MUTATED	1	4	1	3	1
PRX WILD-TYPE	131	105	108	130	29

'PRX MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0601 (Fisher's exact test), Q value = 0.44

Table S376. Gene #37: 'PRX MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	134	71	36	66	91	41	74
PRX MUTATED	1	4	0	2	0	2	1
PRX WILD-TYPE	133	67	36	64	91	39	73

'PRX MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.539 (Fisher's exact test), Q value = 1

Table S377. Gene #37: 'PRX MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
PRX MUTATED	1	3	5	1
PRX WILD-TYPE	135	104	178	82

'PRX MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.00117 (Fisher's exact test), Q value = 0.024

Table S378. Gene #37: 'PRX MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
PRX MUTATED	1	2	7
PRX WILD-TYPE	221	182	96

Figure S132. Get High-res Image Gene #37: 'PRX MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

'PRX MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.185 (Fisher's exact test), Q value = 0.81

Table S379. Gene #37: 'PRX MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
PRX MUTATED	2	2	6
PRX WILD-TYPE	182	160	153

'PRX MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.0733 (Fisher's exact test), Q value = 0.5

Table S380. Gene #37: 'PRX MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
PRX MUTATED	1	1	3	5
PRX WILD-TYPE	89	137	185	84

'NKD2 MUTATION STATUS' versus 'CN_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S381. Gene #38: 'NKD2 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	169	120	221
NKD2 MUTATED	1	1	2
NKD2 WILD-TYPE	168	119	219

'NKD2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.879 (Fisher's exact test), Q value = 1

Table S382. Gene #38: 'NKD2 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	222	81	168	42
NKD2 MUTATED	2	1	1	0
NKD2 WILD-TYPE	220	80	167	42

'NKD2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.639 (Fisher's exact test), Q value = 1

Table S383. Gene #38: 'NKD2 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	132	109	109	133	30
NKD2 MUTATED	2	1	1	0	0
NKD2 WILD-TYPE	130	108	108	133	30

'NKD2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.464 (Fisher's exact test), Q value = 1

Table S384. Gene #38: 'NKD2 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	134	71	36	66	91	41	74
NKD2 MUTATED	1	1	1	1	0	0	0
NKD2 WILD-TYPE	133	70	35	65	91	41	74

'NKD2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.364 (Fisher's exact test), Q value = 0.98

Table S385. Gene #38: 'NKD2 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
NKD2 MUTATED	0	2	1	1
NKD2 WILD-TYPE	136	105	182	82

'NKD2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S386. Gene #38: 'NKD2 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
NKD2 MUTATED	2	1	1
NKD2 WILD-TYPE	220	183	102

'NKD2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S387. Gene #38: 'NKD2 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
NKD2 MUTATED	2	1	1
NKD2 WILD-TYPE	182	161	158

'NKD2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.839 (Fisher's exact test), Q value = 1

Table S388. Gene #38: 'NKD2 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
NKD2 MUTATED	1	1	1	1
NKD2 WILD-TYPE	89	137	187	88

'IRS4 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.082 (Fisher's exact test), Q value = 0.52

Table S389. Gene #39: 'IRS4 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	169	120	221
IRS4 MUTATED	2	4	1
IRS4 WILD-TYPE	167	116	220

'IRS4 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.375 (Fisher's exact test), Q value = 1

Table S390. Gene #39: 'IRS4 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	222	81	168	42
IRS4 MUTATED	3	2	1	1
IRS4 WILD-TYPE	219	79	167	41

'IRS4 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.843 (Fisher's exact test), Q value = 1

Table S391. Gene #39: 'IRS4 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	52	62	68	74
IRS4 MUTATED	0	1	2	1
IRS4 WILD-TYPE	52	61	66	73

'IRS4 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.261 (Fisher's exact test), Q value = 0.89

Table S392. Gene #39: 'IRS4 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	67	131	58
IRS4 MUTATED	0	2	2
IRS4 WILD-TYPE	67	129	56

'IRS4 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.6 (Fisher's exact test), Q value = 1

Table S393. Gene #39: 'IRS4 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	132	109	109	133	30
IRS4 MUTATED	3	2	0	2	0
IRS4 WILD-TYPE	129	107	109	131	30

'IRS4 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.135 (Fisher's exact test), Q value = 0.71

Table S394. Gene #39: 'IRS4 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	134	71	36	66	91	41	74
IRS4 MUTATED	3	0	1	1	0	2	0
IRS4 WILD-TYPE	131	71	35	65	91	39	74

'IRS4 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.415 (Fisher's exact test), Q value = 1

Table S395. Gene #39: 'IRS4 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
IRS4 MUTATED	1	3	3	0
IRS4 WILD-TYPE	135	104	180	83

'IRS4 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.692 (Fisher's exact test), Q value = 1

Table S396. Gene #39: 'IRS4 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
IRS4 MUTATED	2	3	2
IRS4 WILD-TYPE	220	181	101

'IRS4 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.267 (Fisher's exact test), Q value = 0.89

Table S397. Gene #39: 'IRS4 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
IRS4 MUTATED	1	2	4
IRS4 WILD-TYPE	183	160	155

'IRS4 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S398. Gene #39: 'IRS4 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
IRS4 MUTATED	1	2	3	1
IRS4 WILD-TYPE	89	136	185	88

'SPTAN1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.726 (Fisher's exact test), Q value = 1

Table S399. Gene #40: 'SPTAN1 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	169	120	221
SPTAN1 MUTATED	1	2	2
SPTAN1 WILD-TYPE	168	118	219

'SPTAN1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.465 (Fisher's exact test), Q value = 1

Table S400. Gene #40: 'SPTAN1 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	222	81	168	42
SPTAN1 MUTATED	2	2	1	0
SPTAN1 WILD-TYPE	220	79	167	42

'SPTAN1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.842 (Fisher's exact test), Q value = 1

Table S401. Gene #40: 'SPTAN1 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	52	62	68	74
SPTAN1 MUTATED	0	1	2	1
SPTAN1 WILD-TYPE	52	61	66	73

'SPTAN1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.668 (Fisher's exact test), Q value = 1

Table S402. Gene #40: 'SPTAN1 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	67	131	58
SPTAN1 MUTATED	0	3	1
SPTAN1 WILD-TYPE	67	128	57

'SPTAN1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.829 (Fisher's exact test), Q value = 1

Table S403. Gene #40: 'SPTAN1 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	132	109	109	133	30
SPTAN1 MUTATED	2	1	0	2	0
SPTAN1 WILD-TYPE	130	108	109	131	30

'SPTAN1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.194 (Fisher's exact test), Q value = 0.84

Table S404. Gene #40: 'SPTAN1 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	134	71	36	66	91	41	74
SPTAN1 MUTATED	1	0	0	1	0	2	1
SPTAN1 WILD-TYPE	133	71	36	65	91	39	73

'SPTAN1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.766 (Fisher's exact test), Q value = 1

Table S405. Gene #40: 'SPTAN1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
SPTAN1 MUTATED	1	2	2	0
SPTAN1 WILD-TYPE	135	105	181	83

'SPTAN1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.529 (Fisher's exact test), Q value = 1

Table S406. Gene #40: 'SPTAN1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
SPTAN1 MUTATED	2	1	2
SPTAN1 WILD-TYPE	220	183	101

'SPTAN1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.454 (Fisher's exact test), Q value = 1

Table S407. Gene #40: 'SPTAN1 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
SPTAN1 MUTATED	1	1	3
SPTAN1 WILD-TYPE	183	161	156

'SPTAN1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S408. Gene #40: 'SPTAN1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
SPTAN1 MUTATED	1	1	2	1
SPTAN1 WILD-TYPE	89	137	186	88

'CIB1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.824 (Fisher's exact test), Q value = 1

Table S409. Gene #41: 'CIB1 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	169	120	221
CIB1 MUTATED	2	1	1
CIB1 WILD-TYPE	167	119	220

'CIB1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S410. Gene #41: 'CIB1 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	222	81	168	42
CIB1 MUTATED	2	0	2	0
CIB1 WILD-TYPE	220	81	166	42

'CIB1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.338 (Fisher's exact test), Q value = 0.95

Table S411. Gene #41: 'CIB1 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	52	62	68	74
CIB1 MUTATED	0	2	0	1
CIB1 WILD-TYPE	52	60	68	73

'CIB1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.608 (Fisher's exact test), Q value = 1

Table S412. Gene #41: 'CIB1 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	67	131	58
CIB1 MUTATED	0	2	1
CIB1 WILD-TYPE	67	129	57

'CIB1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.604 (Fisher's exact test), Q value = 1

Table S413. Gene #41: 'CIB1 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	132	109	109	133	30
CIB1 MUTATED	0	1	2	1	0
CIB1 WILD-TYPE	132	108	107	132	30

'CIB1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.174 (Fisher's exact test), Q value = 0.8

Table S414. Gene #41: 'CIB1 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	134	71	36	66	91	41	74
CIB1 MUTATED	0	0	1	0	1	1	1
CIB1 WILD-TYPE	134	71	35	66	90	40	73

'CIB1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.219 (Fisher's exact test), Q value = 0.86

Table S415. Gene #41: 'CIB1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
CIB1 MUTATED	0	1	1	2
CIB1 WILD-TYPE	136	106	182	81

'CIB1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0447 (Fisher's exact test), Q value = 0.38

Table S416. Gene #41: 'CIB1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
CIB1 MUTATED	0	4	0
CIB1 WILD-TYPE	222	180	103

Figure S133. Get High-res Image Gene #41: 'CIB1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

'CIB1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.118 (Fisher's exact test), Q value = 0.65

Table S417. Gene #41: 'CIB1 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
CIB1 MUTATED	0	3	1
CIB1 WILD-TYPE	184	159	158

'CIB1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.322 (Fisher's exact test), Q value = 0.95

Table S418. Gene #41: 'CIB1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
CIB1 MUTATED	0	3	1	0
CIB1 WILD-TYPE	90	135	187	89

'EIF1AX MUTATION STATUS' versus 'CN_CNMF'

P value = 0.363 (Fisher's exact test), Q value = 0.98

Table S419. Gene #42: 'EIF1AX MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	169	120	221
EIF1AX MUTATED	0	1	3
EIF1AX WILD-TYPE	169	119	218

'EIF1AX MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.263 (Fisher's exact test), Q value = 0.89

Table S420. Gene #42: 'EIF1AX MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	222	81	168	42
EIF1AX MUTATED	4	0	0	0
EIF1AX WILD-TYPE	218	81	168	42

'EIF1AX MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.41 (Fisher's exact test), Q value = 1

Table S421. Gene #42: 'EIF1AX MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	52	62	68	74
EIF1AX MUTATED	0	0	2	2
EIF1AX WILD-TYPE	52	62	66	72

'EIF1AX MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.261 (Fisher's exact test), Q value = 0.89

Table S422. Gene #42: 'EIF1AX MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	67	131	58
EIF1AX MUTATED	0	2	2
EIF1AX WILD-TYPE	67	129	56

'EIF1AX MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.838 (Fisher's exact test), Q value = 1

Table S423. Gene #42: 'EIF1AX MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	132	109	109	133	30
EIF1AX MUTATED	2	1	0	1	0
EIF1AX WILD-TYPE	130	108	109	132	30

'EIF1AX MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.512 (Fisher's exact test), Q value = 1

Table S424. Gene #42: 'EIF1AX MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	134	71	36	66	91	41	74
EIF1AX MUTATED	2	0	0	1	0	1	0
EIF1AX WILD-TYPE	132	71	36	65	91	40	74

'EIF1AX MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.762 (Fisher's exact test), Q value = 1

Table S425. Gene #42: 'EIF1AX MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
EIF1AX MUTATED	2	1	1	0
EIF1AX WILD-TYPE	134	106	182	83

'EIF1AX MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.265 (Fisher's exact test), Q value = 0.89

Table S426. Gene #42: 'EIF1AX MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
EIF1AX MUTATED	3	0	1
EIF1AX WILD-TYPE	219	184	102

'EIF1AX MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.394 (Fisher's exact test), Q value = 1

Table S427. Gene #42: 'EIF1AX MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
EIF1AX MUTATED	3	1	0
EIF1AX WILD-TYPE	181	161	159

'EIF1AX MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.0777 (Fisher's exact test), Q value = 0.51

Table S428. Gene #42: 'EIF1AX MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
EIF1AX MUTATED	2	2	0	0
EIF1AX WILD-TYPE	88	136	188	89

'WRN MUTATION STATUS' versus 'CN_CNMF'

P value = 0.207 (Fisher's exact test), Q value = 0.85

Table S429. Gene #43: 'WRN MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	169	120	221
WRN MUTATED	0	1	4
WRN WILD-TYPE	169	119	217

'WRN MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0762 (Fisher's exact test), Q value = 0.51

Table S430. Gene #43: 'WRN MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	222	81	168	42
WRN MUTATED	0	1	4	0
WRN WILD-TYPE	222	80	164	42

'WRN MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0304 (Fisher's exact test), Q value = 0.29

Table S431. Gene #43: 'WRN MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	132	109	109	133	30
WRN MUTATED	0	1	4	0	0
WRN WILD-TYPE	132	108	105	133	30

Figure S134. Get High-res Image Gene #43: 'WRN MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

'WRN MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0161 (Fisher's exact test), Q value = 0.19

Table S432. Gene #43: 'WRN MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	134	71	36	66	91	41	74
WRN MUTATED	0	0	2	0	2	1	0
WRN WILD-TYPE	134	71	34	66	89	40	74

Figure S135. Get High-res Image Gene #43: 'WRN MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'WRN MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.0562 (Fisher's exact test), Q value = 0.42

Table S433. Gene #43: 'WRN MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
WRN MUTATED	0	1	1	3
WRN WILD-TYPE	136	106	182	80

'WRN MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S434. Gene #43: 'WRN MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
WRN MUTATED	2	2	1
WRN WILD-TYPE	220	182	102

'WRN MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.0442 (Fisher's exact test), Q value = 0.37

Table S435. Gene #43: 'WRN MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
WRN MUTATED	0	4	1
WRN WILD-TYPE	184	158	158

Figure S136. Get High-res Image Gene #43: 'WRN MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

'WRN MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.455 (Fisher's exact test), Q value = 1

Table S436. Gene #43: 'WRN MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
WRN MUTATED	0	3	2	0
WRN WILD-TYPE	90	135	186	89

'SCN4A MUTATION STATUS' versus 'CN_CNMF'

P value = 0.114 (Fisher's exact test), Q value = 0.64

Table S437. Gene #44: 'SCN4A MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	169	120	221
SCN4A MUTATED	0	1	5
SCN4A WILD-TYPE	169	119	216

'SCN4A MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.346 (Fisher's exact test), Q value = 0.95

Table S438. Gene #44: 'SCN4A MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	222	81	168	42
SCN4A MUTATED	1	1	3	1
SCN4A WILD-TYPE	221	80	165	41

'SCN4A MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.782 (Fisher's exact test), Q value = 1

Table S439. Gene #44: 'SCN4A MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	52	62	68	74
SCN4A MUTATED	1	0	1	2
SCN4A WILD-TYPE	51	62	67	72

'SCN4A MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S440. Gene #44: 'SCN4A MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	67	131	58
SCN4A MUTATED	1	2	1
SCN4A WILD-TYPE	66	129	57

'SCN4A MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.487 (Fisher's exact test), Q value = 1

Table S441. Gene #44: 'SCN4A MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	132	109	109	133	30
SCN4A MUTATED	0	1	2	3	0
SCN4A WILD-TYPE	132	108	107	130	30

'SCN4A MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.11 (Fisher's exact test), Q value = 0.63

Table S442. Gene #44: 'SCN4A MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	134	71	36	66	91	41	74
SCN4A MUTATED	0	0	0	1	1	1	3
SCN4A WILD-TYPE	134	71	36	65	90	40	71

'SCN4A MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.571 (Fisher's exact test), Q value = 1

Table S443. Gene #44: 'SCN4A MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
SCN4A MUTATED	1	1	4	0
SCN4A WILD-TYPE	135	106	179	83

'SCN4A MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.868 (Fisher's exact test), Q value = 1

Table S444. Gene #44: 'SCN4A MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
SCN4A MUTATED	2	3	1
SCN4A WILD-TYPE	220	181	102

'SCN4A MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.0688 (Fisher's exact test), Q value = 0.48

Table S445. Gene #44: 'SCN4A MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
SCN4A MUTATED	0	2	4
SCN4A WILD-TYPE	184	160	155

'SCN4A MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.414 (Fisher's exact test), Q value = 1

Table S446. Gene #44: 'SCN4A MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
SCN4A MUTATED	0	2	4	0
SCN4A WILD-TYPE	90	136	184	89

'PLCG1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.00458 (Fisher's exact test), Q value = 0.073

Table S447. Gene #45: 'PLCG1 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	169	120	221
PLCG1 MUTATED	0	5	1
PLCG1 WILD-TYPE	169	115	220

Figure S137. Get High-res Image Gene #45: 'PLCG1 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

'PLCG1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0273 (Fisher's exact test), Q value = 0.27

Table S448. Gene #45: 'PLCG1 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	222	81	168	42
PLCG1 MUTATED	1	4	1	0
PLCG1 WILD-TYPE	221	77	167	42

Figure S138. Get High-res Image Gene #45: 'PLCG1 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

'PLCG1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.0217 (Fisher's exact test), Q value = 0.24

Table S449. Gene #45: 'PLCG1 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	52	62	68	74
PLCG1 MUTATED	0	3	0	0
PLCG1 WILD-TYPE	52	59	68	74

Figure S139. Get High-res Image Gene #45: 'PLCG1 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

'PLCG1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.433 (Fisher's exact test), Q value = 1

Table S450. Gene #45: 'PLCG1 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	67	131	58
PLCG1 MUTATED	0	3	0
PLCG1 WILD-TYPE	67	128	58

'PLCG1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0197 (Fisher's exact test), Q value = 0.22

Table S451. Gene #45: 'PLCG1 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	132	109	109	133	30
PLCG1 MUTATED	1	4	0	0	1
PLCG1 WILD-TYPE	131	105	109	133	29

Figure S140. Get High-res Image Gene #45: 'PLCG1 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

'PLCG1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.374 (Fisher's exact test), Q value = 1

Table S452. Gene #45: 'PLCG1 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	134	71	36	66	91	41	74
PLCG1 MUTATED	1	3	0	1	1	0	0
PLCG1 WILD-TYPE	133	68	36	65	90	41	74

'PLCG1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.0267 (Fisher's exact test), Q value = 0.27

Table S453. Gene #45: 'PLCG1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
PLCG1 MUTATED	5	0	1	0
PLCG1 WILD-TYPE	131	107	182	83

Figure S141. Get High-res Image Gene #45: 'PLCG1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

'PLCG1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0651 (Fisher's exact test), Q value = 0.47

Table S454. Gene #45: 'PLCG1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
PLCG1 MUTATED	3	0	3
PLCG1 WILD-TYPE	219	184	100

'PLCG1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.0537 (Fisher's exact test), Q value = 0.42

Table S455. Gene #45: 'PLCG1 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
PLCG1 MUTATED	5	1	0
PLCG1 WILD-TYPE	179	161	159

'PLCG1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.147 (Fisher's exact test), Q value = 0.75

Table S456. Gene #45: 'PLCG1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
PLCG1 MUTATED	0	2	1	3
PLCG1 WILD-TYPE	90	136	187	86

'DLC1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0714 (Fisher's exact test), Q value = 0.49

Table S457. Gene #46: 'DLC1 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	169	120	221
DLC1 MUTATED	1	4	1
DLC1 WILD-TYPE	168	116	220

'DLC1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.235 (Fisher's exact test), Q value = 0.87

Table S458. Gene #46: 'DLC1 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	222	81	168	42
DLC1 MUTATED	2	3	1	0
DLC1 WILD-TYPE	220	78	167	42

'DLC1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.574 (Fisher's exact test), Q value = 1

Table S459. Gene #46: 'DLC1 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	52	62	68	74
DLC1 MUTATED	1	1	2	0
DLC1 WILD-TYPE	51	61	66	74

'DLC1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S460. Gene #46: 'DLC1 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	67	131	58
DLC1 MUTATED	1	2	1
DLC1 WILD-TYPE	66	129	57

'DLC1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.446 (Fisher's exact test), Q value = 1

Table S461. Gene #46: 'DLC1 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	132	109	109	133	30
DLC1 MUTATED	2	3	0	1	0
DLC1 WILD-TYPE	130	106	109	132	30

'DLC1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.528 (Fisher's exact test), Q value = 1

Table S462. Gene #46: 'DLC1 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	134	71	36	66	91	41	74
DLC1 MUTATED	2	2	0	0	0	1	1
DLC1 WILD-TYPE	132	69	36	66	91	40	73

'DLC1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.893 (Fisher's exact test), Q value = 1

Table S463. Gene #46: 'DLC1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
DLC1 MUTATED	1	2	2	1
DLC1 WILD-TYPE	135	105	181	82

'DLC1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.152 (Fisher's exact test), Q value = 0.76

Table S464. Gene #46: 'DLC1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
DLC1 MUTATED	1	2	3
DLC1 WILD-TYPE	221	182	100

'DLC1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.782 (Fisher's exact test), Q value = 1

Table S465. Gene #46: 'DLC1 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
DLC1 MUTATED	3	1	2
DLC1 WILD-TYPE	181	161	157

'DLC1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.139 (Fisher's exact test), Q value = 0.72

Table S466. Gene #46: 'DLC1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
DLC1 MUTATED	0	0	4	2
DLC1 WILD-TYPE	90	138	184	87

'TMEM216 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.254 (Fisher's exact test), Q value = 0.89

Table S467. Gene #47: 'TMEM216 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	169	120	221
TMEM216 MUTATED	2	1	0
TMEM216 WILD-TYPE	167	119	221

'TMEM216 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S468. Gene #47: 'TMEM216 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	222	81	168	42
TMEM216 MUTATED	2	0	1	0
TMEM216 WILD-TYPE	220	81	167	42

'TMEM216 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.791 (Fisher's exact test), Q value = 1

Table S469. Gene #47: 'TMEM216 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	52	62	68	74
TMEM216 MUTATED	1	1	0	1
TMEM216 WILD-TYPE	51	61	68	73

'TMEM216 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.793 (Fisher's exact test), Q value = 1

Table S470. Gene #47: 'TMEM216 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	67	131	58
TMEM216 MUTATED	1	1	1
TMEM216 WILD-TYPE	66	130	57

'TMEM216 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S471. Gene #47: 'TMEM216 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	132	109	109	133	30
TMEM216 MUTATED	1	0	1	1	0
TMEM216 WILD-TYPE	131	109	108	132	30

'TMEM216 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.448 (Fisher's exact test), Q value = 1

Table S472. Gene #47: 'TMEM216 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	134	71	36	66	91	41	74
TMEM216 MUTATED	1	0	1	0	0	0	1
TMEM216 WILD-TYPE	133	71	35	66	91	41	73

'TMEM216 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.52 (Fisher's exact test), Q value = 1

Table S473. Gene #47: 'TMEM216 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
TMEM216 MUTATED	0	1	1	1
TMEM216 WILD-TYPE	136	106	182	82

'TMEM216 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.603 (Fisher's exact test), Q value = 1

Table S474. Gene #47: 'TMEM216 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
TMEM216 MUTATED	1	2	0
TMEM216 WILD-TYPE	221	182	103

'TMEM216 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.306 (Fisher's exact test), Q value = 0.93

Table S475. Gene #47: 'TMEM216 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
TMEM216 MUTATED	0	2	1
TMEM216 WILD-TYPE	184	160	158

'TMEM216 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.668 (Fisher's exact test), Q value = 1

Table S476. Gene #47: 'TMEM216 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
TMEM216 MUTATED	0	2	1	0
TMEM216 WILD-TYPE	90	136	187	89

'MYT1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0153 (Fisher's exact test), Q value = 0.19

Table S477. Gene #48: 'MYT1 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	169	120	221
MYT1 MUTATED	5	1	0
MYT1 WILD-TYPE	164	119	221

Figure S142. Get High-res Image Gene #48: 'MYT1 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

'MYT1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.207 (Fisher's exact test), Q value = 0.85

Table S478. Gene #48: 'MYT1 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	222	81	168	42
MYT1 MUTATED	4	1	0	1
MYT1 WILD-TYPE	218	80	168	41

'MYT1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.447 (Fisher's exact test), Q value = 1

Table S479. Gene #48: 'MYT1 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	132	109	109	133	30
MYT1 MUTATED	2	3	0	1	0
MYT1 WILD-TYPE	130	106	109	132	30

'MYT1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.032 (Fisher's exact test), Q value = 0.3

Table S480. Gene #48: 'MYT1 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	134	71	36	66	91	41	74
MYT1 MUTATED	2	0	0	1	0	3	0
MYT1 WILD-TYPE	132	71	36	65	91	38	74

Figure S143. Get High-res Image Gene #48: 'MYT1 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'MYT1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.429 (Fisher's exact test), Q value = 1

Table S481. Gene #48: 'MYT1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
MYT1 MUTATED	0	2	3	1
MYT1 WILD-TYPE	136	105	180	82

'MYT1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.758 (Fisher's exact test), Q value = 1

Table S482. Gene #48: 'MYT1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
MYT1 MUTATED	2	2	2
MYT1 WILD-TYPE	220	182	101

'MYT1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.453 (Fisher's exact test), Q value = 1

Table S483. Gene #48: 'MYT1 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
MYT1 MUTATED	1	2	3
MYT1 WILD-TYPE	183	160	156

'MYT1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.94 (Fisher's exact test), Q value = 1

Table S484. Gene #48: 'MYT1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
MYT1 MUTATED	1	1	3	1
MYT1 WILD-TYPE	89	137	185	88

'SMARCB1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.822 (Fisher's exact test), Q value = 1

Table S485. Gene #49: 'SMARCB1 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	169	120	221
SMARCB1 MUTATED	2	1	1
SMARCB1 WILD-TYPE	167	119	220

'SMARCB1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.881 (Fisher's exact test), Q value = 1

Table S486. Gene #49: 'SMARCB1 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	222	81	168	42
SMARCB1 MUTATED	2	1	1	0
SMARCB1 WILD-TYPE	220	80	167	42

'SMARCB1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.0399 (Fisher's exact test), Q value = 0.35

Table S487. Gene #49: 'SMARCB1 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	52	62	68	74
SMARCB1 MUTATED	0	0	3	0
SMARCB1 WILD-TYPE	52	62	65	74

Figure S144. Get High-res Image Gene #49: 'SMARCB1 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

'SMARCB1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.43 (Fisher's exact test), Q value = 1

Table S488. Gene #49: 'SMARCB1 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	67	131	58
SMARCB1 MUTATED	0	3	0
SMARCB1 WILD-TYPE	67	128	58

'SMARCB1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.928 (Fisher's exact test), Q value = 1

Table S489. Gene #49: 'SMARCB1 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	132	109	109	133	30
SMARCB1 MUTATED	1	1	0	2	0
SMARCB1 WILD-TYPE	131	108	109	131	30

'SMARCB1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.594 (Fisher's exact test), Q value = 1

Table S490. Gene #49: 'SMARCB1 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	134	71	36	66	91	41	74
SMARCB1 MUTATED	2	0	0	0	0	1	1
SMARCB1 WILD-TYPE	132	71	36	66	91	40	73

'SMARCB1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.438 (Fisher's exact test), Q value = 1

Table S491. Gene #49: 'SMARCB1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
SMARCB1 MUTATED	0	1	3	0
SMARCB1 WILD-TYPE	136	106	180	83

'SMARCB1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.683 (Fisher's exact test), Q value = 1

Table S492. Gene #49: 'SMARCB1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
SMARCB1 MUTATED	1	2	1
SMARCB1 WILD-TYPE	221	182	102

'SMARCB1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.076 (Fisher's exact test), Q value = 0.51

Table S493. Gene #49: 'SMARCB1 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
SMARCB1 MUTATED	0	1	3
SMARCB1 WILD-TYPE	184	161	156

'SMARCB1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.394 (Fisher's exact test), Q value = 1

Table S494. Gene #49: 'SMARCB1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
SMARCB1 MUTATED	1	0	3	0
SMARCB1 WILD-TYPE	89	138	185	89

'RIPK4 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0181 (Fisher's exact test), Q value = 0.21

Table S495. Gene #50: 'RIPK4 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	169	120	221
RIPK4 MUTATED	0	5	3
RIPK4 WILD-TYPE	169	115	218

Figure S145. Get High-res Image Gene #50: 'RIPK4 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

'RIPK4 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.00216 (Fisher's exact test), Q value = 0.041

Table S496. Gene #50: 'RIPK4 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	222	81	168	42
RIPK4 MUTATED	0	5	3	0
RIPK4 WILD-TYPE	222	76	165	42

Figure S146. Get High-res Image Gene #50: 'RIPK4 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

'RIPK4 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.343 (Fisher's exact test), Q value = 0.95

Table S497. Gene #50: 'RIPK4 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	52	62	68	74
RIPK4 MUTATED	2	1	1	0
RIPK4 WILD-TYPE	50	61	67	74

'RIPK4 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.81 (Fisher's exact test), Q value = 1

Table S498. Gene #50: 'RIPK4 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	67	131	58
RIPK4 MUTATED	1	3	0
RIPK4 WILD-TYPE	66	128	58

'RIPK4 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0075 (Fisher's exact test), Q value = 0.1

Table S499. Gene #50: 'RIPK4 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	132	109	109	133	30
RIPK4 MUTATED	0	5	2	0	1
RIPK4 WILD-TYPE	132	104	107	133	29

Figure S147. Get High-res Image Gene #50: 'RIPK4 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

'RIPK4 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0193 (Fisher's exact test), Q value = 0.22

Table S500. Gene #50: 'RIPK4 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	134	71	36	66	91	41	74
RIPK4 MUTATED	0	4	1	0	2	1	0
RIPK4 WILD-TYPE	134	67	35	66	89	40	74

Figure S148. Get High-res Image Gene #50: 'RIPK4 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'RIPK4 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.3 (Fisher's exact test), Q value = 0.93

Table S501. Gene #50: 'RIPK4 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
RIPK4 MUTATED	1	4	2	1
RIPK4 WILD-TYPE	135	103	181	82

'RIPK4 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0192 (Fisher's exact test), Q value = 0.22

Table S502. Gene #50: 'RIPK4 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
RIPK4 MUTATED	1	2	5
RIPK4 WILD-TYPE	221	182	98

Figure S149. Get High-res Image Gene #50: 'RIPK4 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

'RIPK4 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.504 (Fisher's exact test), Q value = 1

Table S503. Gene #50: 'RIPK4 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
RIPK4 MUTATED	4	1	3
RIPK4 WILD-TYPE	180	161	156

'RIPK4 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.109 (Fisher's exact test), Q value = 0.62

Table S504. Gene #50: 'RIPK4 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
RIPK4 MUTATED	0	2	2	4
RIPK4 WILD-TYPE	90	136	186	85

'NEU2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.534 (Fisher's exact test), Q value = 1

Table S505. Gene #51: 'NEU2 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	169	120	221
NEU2 MUTATED	2	2	1
NEU2 WILD-TYPE	167	118	220

'NEU2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.818 (Fisher's exact test), Q value = 1

Table S506. Gene #51: 'NEU2 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	222	81	168	42
NEU2 MUTATED	3	1	1	0
NEU2 WILD-TYPE	219	80	167	42

'NEU2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0787 (Fisher's exact test), Q value = 0.51

Table S507. Gene #51: 'NEU2 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	132	109	109	133	30
NEU2 MUTATED	3	0	1	0	1
NEU2 WILD-TYPE	129	109	108	133	29

'NEU2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.87 (Fisher's exact test), Q value = 1

Table S508. Gene #51: 'NEU2 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	134	71	36	66	91	41	74
NEU2 MUTATED	3	1	0	0	1	0	0
NEU2 WILD-TYPE	131	70	36	66	90	41	74

'NEU2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.305 (Fisher's exact test), Q value = 0.93

Table S509. Gene #51: 'NEU2 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
NEU2 MUTATED	0	1	2	2
NEU2 WILD-TYPE	136	106	181	81

'NEU2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S510. Gene #51: 'NEU2 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
NEU2 MUTATED	2	2	1
NEU2 WILD-TYPE	220	182	102

'NEU2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.456 (Fisher's exact test), Q value = 1

Table S511. Gene #51: 'NEU2 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
NEU2 MUTATED	1	1	3
NEU2 WILD-TYPE	183	161	156

'NEU2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.71 (Fisher's exact test), Q value = 1

Table S512. Gene #51: 'NEU2 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
NEU2 MUTATED	0	1	3	1
NEU2 WILD-TYPE	90	137	185	88

'PTPRH MUTATION STATUS' versus 'CN_CNMF'

P value = 0.479 (Fisher's exact test), Q value = 1

Table S513. Gene #52: 'PTPRH MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	169	120	221
PTPRH MUTATED	3	3	2
PTPRH WILD-TYPE	166	117	219

'PTPRH MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.444 (Fisher's exact test), Q value = 1

Table S514. Gene #52: 'PTPRH MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	222	81	168	42
PTPRH MUTATED	5	2	1	0
PTPRH WILD-TYPE	217	79	167	42

'PTPRH MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.46 (Fisher's exact test), Q value = 1

Table S515. Gene #52: 'PTPRH MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	52	62	68	74
PTPRH MUTATED	0	3	1	2
PTPRH WILD-TYPE	52	59	67	72

'PTPRH MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.638 (Fisher's exact test), Q value = 1

Table S516. Gene #52: 'PTPRH MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	67	131	58
PTPRH MUTATED	2	2	2
PTPRH WILD-TYPE	65	129	56

'PTPRH MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0978 (Fisher's exact test), Q value = 0.58

Table S517. Gene #52: 'PTPRH MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	132	109	109	133	30
PTPRH MUTATED	1	5	0	2	0
PTPRH WILD-TYPE	131	104	109	131	30

'PTPRH MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00202 (Fisher's exact test), Q value = 0.038

Table S518. Gene #52: 'PTPRH MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	134	71	36	66	91	41	74
PTPRH MUTATED	0	1	0	1	0	4	2
PTPRH WILD-TYPE	134	70	36	65	91	37	72

Figure S150. Get High-res Image Gene #52: 'PTPRH MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'PTPRH MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.0579 (Fisher's exact test), Q value = 0.43

Table S519. Gene #52: 'PTPRH MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
PTPRH MUTATED	0	4	4	0
PTPRH WILD-TYPE	136	103	179	83

'PTPRH MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.00199 (Fisher's exact test), Q value = 0.038

Table S520. Gene #52: 'PTPRH MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
PTPRH MUTATED	0	3	5
PTPRH WILD-TYPE	222	181	98

Figure S151. Get High-res Image Gene #52: 'PTPRH MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

'PTPRH MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.203 (Fisher's exact test), Q value = 0.85

Table S521. Gene #52: 'PTPRH MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
PTPRH MUTATED	2	1	5
PTPRH WILD-TYPE	182	161	154

'PTPRH MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.022 (Fisher's exact test), Q value = 0.24

Table S522. Gene #52: 'PTPRH MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
PTPRH MUTATED	0	0	4	4
PTPRH WILD-TYPE	90	138	184	85

Figure S152. Get High-res Image Gene #52: 'PTPRH MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

'MAPK15 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.36 (Fisher's exact test), Q value = 0.98

Table S523. Gene #53: 'MAPK15 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	169	120	221
MAPK15 MUTATED	0	1	3
MAPK15 WILD-TYPE	169	119	218

'MAPK15 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.657 (Fisher's exact test), Q value = 1

Table S524. Gene #53: 'MAPK15 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	222	81	168	42
MAPK15 MUTATED	1	1	2	0
MAPK15 WILD-TYPE	221	80	166	42

'MAPK15 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.198 (Fisher's exact test), Q value = 0.84

Table S525. Gene #53: 'MAPK15 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	52	62	68	74
MAPK15 MUTATED	1	2	0	0
MAPK15 WILD-TYPE	51	60	68	74

'MAPK15 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S526. Gene #53: 'MAPK15 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	67	131	58
MAPK15 MUTATED	1	2	0
MAPK15 WILD-TYPE	66	129	58

'MAPK15 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S527. Gene #53: 'MAPK15 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	132	109	109	133	30
MAPK15 MUTATED	1	1	1	1	0
MAPK15 WILD-TYPE	131	108	108	132	30

'MAPK15 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S528. Gene #53: 'MAPK15 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	134	71	36	66	91	41	74
MAPK15 MUTATED	1	1	0	0	1	0	1
MAPK15 WILD-TYPE	133	70	36	66	90	41	73

'MAPK15 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.539 (Fisher's exact test), Q value = 1

Table S529. Gene #53: 'MAPK15 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
MAPK15 MUTATED	2	0	1	1
MAPK15 WILD-TYPE	134	107	182	82

'MAPK15 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.343 (Fisher's exact test), Q value = 0.95

Table S530. Gene #53: 'MAPK15 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
MAPK15 MUTATED	1	1	2
MAPK15 WILD-TYPE	221	183	101

'MAPK15 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S531. Gene #53: 'MAPK15 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
MAPK15 MUTATED	2	1	1
MAPK15 WILD-TYPE	182	161	158

'MAPK15 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.524 (Fisher's exact test), Q value = 1

Table S532. Gene #53: 'MAPK15 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
MAPK15 MUTATED	1	0	2	1
MAPK15 WILD-TYPE	89	138	186	88

'TPX2 MUTATION STATUS' versus 'CN_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S533. Gene #54: 'TPX2 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	169	120	221
TPX2 MUTATED	2	1	2
TPX2 WILD-TYPE	167	119	219

'TPX2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.816 (Fisher's exact test), Q value = 1

Table S534. Gene #54: 'TPX2 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	222	81	168	42
TPX2 MUTATED	3	1	1	0
TPX2 WILD-TYPE	219	80	167	42

'TPX2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.828 (Fisher's exact test), Q value = 1

Table S535. Gene #54: 'TPX2 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	132	109	109	133	30
TPX2 MUTATED	2	1	0	2	0
TPX2 WILD-TYPE	130	108	109	131	30

'TPX2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.388 (Fisher's exact test), Q value = 1

Table S536. Gene #54: 'TPX2 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	134	71	36	66	91	41	74
TPX2 MUTATED	2	0	1	0	0	1	1
TPX2 WILD-TYPE	132	71	35	66	91	40	73

'TPX2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.487 (Fisher's exact test), Q value = 1

Table S537. Gene #54: 'TPX2 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
TPX2 MUTATED	0	1	3	1
TPX2 WILD-TYPE	136	106	180	82

'TPX2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0732 (Fisher's exact test), Q value = 0.5

Table S538. Gene #54: 'TPX2 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
TPX2 MUTATED	0	4	1
TPX2 WILD-TYPE	222	180	102

'TPX2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.169 (Fisher's exact test), Q value = 0.79

Table S539. Gene #54: 'TPX2 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
TPX2 MUTATED	0	2	3
TPX2 WILD-TYPE	184	160	156

'TPX2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.32 (Fisher's exact test), Q value = 0.95

Table S540. Gene #54: 'TPX2 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
TPX2 MUTATED	0	1	4	0
TPX2 WILD-TYPE	90	137	184	89

'SLC12A7 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.167 (Fisher's exact test), Q value = 0.78

Table S541. Gene #55: 'SLC12A7 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	169	120	221
SLC12A7 MUTATED	1	4	2
SLC12A7 WILD-TYPE	168	116	219

'SLC12A7 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.404 (Fisher's exact test), Q value = 1

Table S542. Gene #55: 'SLC12A7 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	222	81	168	42
SLC12A7 MUTATED	2	2	2	1
SLC12A7 WILD-TYPE	220	79	166	41

'SLC12A7 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.21 (Fisher's exact test), Q value = 0.85

Table S543. Gene #55: 'SLC12A7 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	52	62	68	74
SLC12A7 MUTATED	0	0	3	1
SLC12A7 WILD-TYPE	52	62	65	73

'SLC12A7 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.812 (Fisher's exact test), Q value = 1

Table S544. Gene #55: 'SLC12A7 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	67	131	58
SLC12A7 MUTATED	1	3	0
SLC12A7 WILD-TYPE	66	128	58

'SLC12A7 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.921 (Fisher's exact test), Q value = 1

Table S545. Gene #55: 'SLC12A7 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	132	109	109	133	30
SLC12A7 MUTATED	2	2	2	1	0
SLC12A7 WILD-TYPE	130	107	107	132	30

'SLC12A7 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.862 (Fisher's exact test), Q value = 1

Table S546. Gene #55: 'SLC12A7 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	134	71	36	66	91	41	74
SLC12A7 MUTATED	2	1	1	0	1	1	1
SLC12A7 WILD-TYPE	132	70	35	66	90	40	73

'SLC12A7 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.87 (Fisher's exact test), Q value = 1

Table S547. Gene #55: 'SLC12A7 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
SLC12A7 MUTATED	3	1	2	1
SLC12A7 WILD-TYPE	133	106	181	82

'SLC12A7 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.786 (Fisher's exact test), Q value = 1

Table S548. Gene #55: 'SLC12A7 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
SLC12A7 MUTATED	3	2	2
SLC12A7 WILD-TYPE	219	182	101

'SLC12A7 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.894 (Fisher's exact test), Q value = 1

Table S549. Gene #55: 'SLC12A7 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
SLC12A7 MUTATED	2	3	2
SLC12A7 WILD-TYPE	182	159	157

'SLC12A7 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S550. Gene #55: 'SLC12A7 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
SLC12A7 MUTATED	1	2	3	1
SLC12A7 WILD-TYPE	89	136	185	88

'PLXNA3 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.21 (Fisher's exact test), Q value = 0.85

Table S551. Gene #56: 'PLXNA3 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	169	120	221
PLXNA3 MUTATED	1	4	4
PLXNA3 WILD-TYPE	168	116	217

'PLXNA3 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.271 (Fisher's exact test), Q value = 0.9

Table S552. Gene #56: 'PLXNA3 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	222	81	168	42
PLXNA3 MUTATED	2	3	4	0
PLXNA3 WILD-TYPE	220	78	164	42

'PLXNA3 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.309 (Fisher's exact test), Q value = 0.93

Table S553. Gene #56: 'PLXNA3 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	52	62	68	74
PLXNA3 MUTATED	1	2	3	0
PLXNA3 WILD-TYPE	51	60	65	74

'PLXNA3 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.42 (Fisher's exact test), Q value = 1

Table S554. Gene #56: 'PLXNA3 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	67	131	58
PLXNA3 MUTATED	1	5	0
PLXNA3 WILD-TYPE	66	126	58

'PLXNA3 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.2 (Fisher's exact test), Q value = 0.84

Table S555. Gene #56: 'PLXNA3 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	132	109	109	133	30
PLXNA3 MUTATED	2	3	3	0	1
PLXNA3 WILD-TYPE	130	106	106	133	29

'PLXNA3 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.311 (Fisher's exact test), Q value = 0.94

Table S556. Gene #56: 'PLXNA3 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	134	71	36	66	91	41	74
PLXNA3 MUTATED	2	2	0	0	4	1	0
PLXNA3 WILD-TYPE	132	69	36	66	87	40	74

'PLXNA3 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.352 (Fisher's exact test), Q value = 0.96

Table S557. Gene #56: 'PLXNA3 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
PLXNA3 MUTATED	3	3	1	2
PLXNA3 WILD-TYPE	133	104	182	81

'PLXNA3 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.228 (Fisher's exact test), Q value = 0.86

Table S558. Gene #56: 'PLXNA3 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
PLXNA3 MUTATED	5	1	3
PLXNA3 WILD-TYPE	217	183	100

'PLXNA3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.481 (Fisher's exact test), Q value = 1

Table S559. Gene #56: 'PLXNA3 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
PLXNA3 MUTATED	4	4	1
PLXNA3 WILD-TYPE	180	158	158

'PLXNA3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.876 (Fisher's exact test), Q value = 1

Table S560. Gene #56: 'PLXNA3 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
PLXNA3 MUTATED	1	3	3	2
PLXNA3 WILD-TYPE	89	135	185	87

'RET MUTATION STATUS' versus 'CN_CNMF'

P value = 0.553 (Fisher's exact test), Q value = 1

Table S561. Gene #57: 'RET MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	169	120	221
RET MUTATED	2	3	2
RET WILD-TYPE	167	117	219

'RET MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.32 (Fisher's exact test), Q value = 0.95

Table S562. Gene #57: 'RET MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	222	81	168	42
RET MUTATED	2	3	2	0
RET WILD-TYPE	220	78	166	42

'RET MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.286 (Fisher's exact test), Q value = 0.92

Table S563. Gene #57: 'RET MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	52	62	68	74
RET MUTATED	0	2	1	0
RET WILD-TYPE	52	60	67	74

'RET MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.431 (Fisher's exact test), Q value = 1

Table S564. Gene #57: 'RET MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	67	131	58
RET MUTATED	0	3	0
RET WILD-TYPE	67	128	58

'RET MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.374 (Fisher's exact test), Q value = 1

Table S565. Gene #57: 'RET MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	132	109	109	133	30
RET MUTATED	1	3	0	3	0
RET WILD-TYPE	131	106	109	130	30

'RET MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.445 (Fisher's exact test), Q value = 1

Table S566. Gene #57: 'RET MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	134	71	36	66	91	41	74
RET MUTATED	1	2	1	1	0	1	1
RET WILD-TYPE	133	69	35	65	91	40	73

'RET MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.709 (Fisher's exact test), Q value = 1

Table S567. Gene #57: 'RET MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
RET MUTATED	2	1	4	0
RET WILD-TYPE	134	106	179	83

'RET MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.153 (Fisher's exact test), Q value = 0.76

Table S568. Gene #57: 'RET MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
RET MUTATED	1	3	3
RET WILD-TYPE	221	181	100

'RET MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.148 (Fisher's exact test), Q value = 0.75

Table S569. Gene #57: 'RET MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
RET MUTATED	3	0	4
RET WILD-TYPE	181	162	155

'RET MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.254 (Fisher's exact test), Q value = 0.89

Table S570. Gene #57: 'RET MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
RET MUTATED	1	0	4	2
RET WILD-TYPE	89	138	184	87

'ZNF148 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.222 (Fisher's exact test), Q value = 0.86

Table S571. Gene #58: 'ZNF148 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	169	120	221
ZNF148 MUTATED	0	2	2
ZNF148 WILD-TYPE	169	118	219

'ZNF148 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.144 (Fisher's exact test), Q value = 0.73

Table S572. Gene #58: 'ZNF148 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	222	81	168	42
ZNF148 MUTATED	0	1	3	0
ZNF148 WILD-TYPE	222	80	165	42

'ZNF148 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.606 (Fisher's exact test), Q value = 1

Table S573. Gene #58: 'ZNF148 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	132	109	109	133	30
ZNF148 MUTATED	0	1	2	1	0
ZNF148 WILD-TYPE	132	108	107	132	30

'ZNF148 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.232 (Fisher's exact test), Q value = 0.87

Table S574. Gene #58: 'ZNF148 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	134	71	36	66	91	41	74
ZNF148 MUTATED	0	0	0	0	2	1	1
ZNF148 WILD-TYPE	134	71	36	66	89	40	73

'ZNF148 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.591 (Fisher's exact test), Q value = 1

Table S575. Gene #58: 'ZNF148 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
ZNF148 MUTATED	1	2	1	0
ZNF148 WILD-TYPE	135	105	182	83

'ZNF148 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.265 (Fisher's exact test), Q value = 0.89

Table S576. Gene #58: 'ZNF148 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
ZNF148 MUTATED	3	0	1
ZNF148 WILD-TYPE	219	184	102

'ZNF148 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.696 (Fisher's exact test), Q value = 1

Table S577. Gene #58: 'ZNF148 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
ZNF148 MUTATED	1	1	2
ZNF148 WILD-TYPE	183	161	157

'ZNF148 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.758 (Fisher's exact test), Q value = 1

Table S578. Gene #58: 'ZNF148 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
ZNF148 MUTATED	0	2	2	0
ZNF148 WILD-TYPE	90	136	186	89

'HDAC2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.36 (Fisher's exact test), Q value = 0.98

Table S579. Gene #59: 'HDAC2 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	169	120	221
HDAC2 MUTATED	0	1	3
HDAC2 WILD-TYPE	169	119	218

'HDAC2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.143 (Fisher's exact test), Q value = 0.73

Table S580. Gene #59: 'HDAC2 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	222	81	168	42
HDAC2 MUTATED	0	1	3	0
HDAC2 WILD-TYPE	222	80	165	42

'HDAC2 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.728 (Fisher's exact test), Q value = 1

Table S581. Gene #59: 'HDAC2 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	52	62	68	74
HDAC2 MUTATED	0	2	1	1
HDAC2 WILD-TYPE	52	60	67	73

'HDAC2 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.265 (Fisher's exact test), Q value = 0.89

Table S582. Gene #59: 'HDAC2 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	67	131	58
HDAC2 MUTATED	0	2	2
HDAC2 WILD-TYPE	67	129	56

'HDAC2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.606 (Fisher's exact test), Q value = 1

Table S583. Gene #59: 'HDAC2 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	132	109	109	133	30
HDAC2 MUTATED	0	1	2	1	0
HDAC2 WILD-TYPE	132	108	107	132	30

'HDAC2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.177 (Fisher's exact test), Q value = 0.8

Table S584. Gene #59: 'HDAC2 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	134	71	36	66	91	41	74
HDAC2 MUTATED	0	0	1	0	1	1	1
HDAC2 WILD-TYPE	134	71	35	66	90	40	73

'HDAC2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.219 (Fisher's exact test), Q value = 0.86

Table S585. Gene #59: 'HDAC2 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
HDAC2 MUTATED	0	1	1	2
HDAC2 WILD-TYPE	136	106	182	81

'HDAC2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.681 (Fisher's exact test), Q value = 1

Table S586. Gene #59: 'HDAC2 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
HDAC2 MUTATED	1	2	1
HDAC2 WILD-TYPE	221	182	102

'HDAC2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.164 (Fisher's exact test), Q value = 0.78

Table S587. Gene #59: 'HDAC2 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
HDAC2 MUTATED	1	0	3
HDAC2 WILD-TYPE	183	162	156

'HDAC2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.161 (Fisher's exact test), Q value = 0.78

Table S588. Gene #59: 'HDAC2 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
HDAC2 MUTATED	0	0	4	0
HDAC2 WILD-TYPE	90	138	184	89

'RBBP6 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.582 (Fisher's exact test), Q value = 1

Table S589. Gene #60: 'RBBP6 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	169	120	221
RBBP6 MUTATED	1	1	4
RBBP6 WILD-TYPE	168	119	217

'RBBP6 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.323 (Fisher's exact test), Q value = 0.95

Table S590. Gene #60: 'RBBP6 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	222	81	168	42
RBBP6 MUTATED	1	1	4	0
RBBP6 WILD-TYPE	221	80	164	42

'RBBP6 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.028 (Fisher's exact test), Q value = 0.28

Table S591. Gene #60: 'RBBP6 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	132	109	109	133	30
RBBP6 MUTATED	0	2	4	0	0
RBBP6 WILD-TYPE	132	107	105	133	30

Figure S153. Get High-res Image Gene #60: 'RBBP6 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

'RBBP6 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00627 (Fisher's exact test), Q value = 0.093

Table S592. Gene #60: 'RBBP6 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	134	71	36	66	91	41	74
RBBP6 MUTATED	0	0	0	0	4	2	0
RBBP6 WILD-TYPE	134	71	36	66	87	39	74

Figure S154. Get High-res Image Gene #60: 'RBBP6 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'RBBP6 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.282 (Fisher's exact test), Q value = 0.91

Table S593. Gene #60: 'RBBP6 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
RBBP6 MUTATED	0	1	3	2
RBBP6 WILD-TYPE	136	106	180	81

'RBBP6 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.063 (Fisher's exact test), Q value = 0.46

Table S594. Gene #60: 'RBBP6 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
RBBP6 MUTATED	3	0	3
RBBP6 WILD-TYPE	219	184	100

'RBBP6 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.0836 (Fisher's exact test), Q value = 0.52

Table S595. Gene #60: 'RBBP6 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
RBBP6 MUTATED	0	4	2
RBBP6 WILD-TYPE	184	158	157

'RBBP6 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.175 (Fisher's exact test), Q value = 0.8

Table S596. Gene #60: 'RBBP6 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
RBBP6 MUTATED	0	4	1	1
RBBP6 WILD-TYPE	90	134	187	88

'MED9 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.176 (Fisher's exact test), Q value = 0.8

Table S597. Gene #61: 'MED9 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	169	120	221
MED9 MUTATED	0	2	1
MED9 WILD-TYPE	169	118	220

'MED9 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.371 (Fisher's exact test), Q value = 0.99

Table S598. Gene #61: 'MED9 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	222	81	168	42
MED9 MUTATED	1	0	1	1
MED9 WILD-TYPE	221	81	167	41

'MED9 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.217 (Fisher's exact test), Q value = 0.86

Table S599. Gene #61: 'MED9 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	132	109	109	133	30
MED9 MUTATED	1	0	0	1	1
MED9 WILD-TYPE	131	109	109	132	29

'MED9 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.849 (Fisher's exact test), Q value = 1

Table S600. Gene #61: 'MED9 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	134	71	36	66	91	41	74
MED9 MUTATED	1	1	0	0	0	0	1
MED9 WILD-TYPE	133	70	36	66	91	41	73

'MED9 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.88 (Fisher's exact test), Q value = 1

Table S601. Gene #61: 'MED9 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
MED9 MUTATED	1	0	2	0
MED9 WILD-TYPE	135	107	181	83

'MED9 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.795 (Fisher's exact test), Q value = 1

Table S602. Gene #61: 'MED9 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
MED9 MUTATED	1	1	1
MED9 WILD-TYPE	221	183	102

'MED9 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.648 (Fisher's exact test), Q value = 1

Table S603. Gene #61: 'MED9 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
MED9 MUTATED	2	0	1
MED9 WILD-TYPE	182	162	158

'MED9 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.512 (Fisher's exact test), Q value = 1

Table S604. Gene #61: 'MED9 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
MED9 MUTATED	0	0	2	1
MED9 WILD-TYPE	90	138	186	88

'DDX5 MUTATION STATUS' versus 'CN_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S605. Gene #62: 'DDX5 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	169	120	221
DDX5 MUTATED	2	1	2
DDX5 WILD-TYPE	167	119	219

'DDX5 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S606. Gene #62: 'DDX5 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	222	81	168	42
DDX5 MUTATED	2	1	2	0
DDX5 WILD-TYPE	220	80	166	42

'DDX5 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.933 (Fisher's exact test), Q value = 1

Table S607. Gene #62: 'DDX5 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	52	62	68	74
DDX5 MUTATED	1	1	2	1
DDX5 WILD-TYPE	51	61	66	73

'DDX5 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.84 (Fisher's exact test), Q value = 1

Table S608. Gene #62: 'DDX5 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	67	131	58
DDX5 MUTATED	2	2	1
DDX5 WILD-TYPE	65	129	57

'DDX5 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.617 (Fisher's exact test), Q value = 1

Table S609. Gene #62: 'DDX5 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	132	109	109	133	30
DDX5 MUTATED	2	1	2	0	0
DDX5 WILD-TYPE	130	108	107	133	30

'DDX5 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.485 (Fisher's exact test), Q value = 1

Table S610. Gene #62: 'DDX5 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	134	71	36	66	91	41	74
DDX5 MUTATED	2	0	1	0	1	1	0
DDX5 WILD-TYPE	132	71	35	66	90	40	74

'DDX5 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.263 (Fisher's exact test), Q value = 0.89

Table S611. Gene #62: 'DDX5 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
DDX5 MUTATED	0	2	3	0
DDX5 WILD-TYPE	136	105	180	83

'DDX5 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.443 (Fisher's exact test), Q value = 1

Table S612. Gene #62: 'DDX5 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
DDX5 MUTATED	1	3	1
DDX5 WILD-TYPE	221	181	102

'DDX5 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.0276 (Fisher's exact test), Q value = 0.27

Table S613. Gene #62: 'DDX5 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
DDX5 MUTATED	0	1	4
DDX5 WILD-TYPE	184	161	155

Figure S155. Get High-res Image Gene #62: 'DDX5 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

'DDX5 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.317 (Fisher's exact test), Q value = 0.95

Table S614. Gene #62: 'DDX5 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
DDX5 MUTATED	0	1	4	0
DDX5 WILD-TYPE	90	137	184	89

'ZC3H11A MUTATION STATUS' versus 'CN_CNMF'

P value = 8e-04 (Fisher's exact test), Q value = 0.018

Table S615. Gene #63: 'ZC3H11A MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	169	120	221
ZC3H11A MUTATED	0	5	0
ZC3H11A WILD-TYPE	169	115	221

Figure S156. Get High-res Image Gene #63: 'ZC3H11A MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

'ZC3H11A MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 2e-04 (Fisher's exact test), Q value = 0.0052

Table S616. Gene #63: 'ZC3H11A MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	222	81	168	42
ZC3H11A MUTATED	0	5	0	0
ZC3H11A WILD-TYPE	222	76	168	42

Figure S157. Get High-res Image Gene #63: 'ZC3H11A MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

'ZC3H11A MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.00298 (Fisher's exact test), Q value = 0.053

Table S617. Gene #63: 'ZC3H11A MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	132	109	109	133	30
ZC3H11A MUTATED	0	5	0	0	0
ZC3H11A WILD-TYPE	132	104	109	133	30

Figure S158. Get High-res Image Gene #63: 'ZC3H11A MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

'ZC3H11A MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00338 (Fisher's exact test), Q value = 0.059

Table S618. Gene #63: 'ZC3H11A MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	134	71	36	66	91	41	74
ZC3H11A MUTATED	0	4	0	0	0	1	0
ZC3H11A WILD-TYPE	134	67	36	66	91	40	74

Figure S159. Get High-res Image Gene #63: 'ZC3H11A MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'ZC3H11A MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.244 (Fisher's exact test), Q value = 0.88

Table S619. Gene #63: 'ZC3H11A MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
ZC3H11A MUTATED	1	3	1	0
ZC3H11A WILD-TYPE	135	104	182	83

'ZC3H11A MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.00722 (Fisher's exact test), Q value = 0.1

Table S620. Gene #63: 'ZC3H11A MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
ZC3H11A MUTATED	1	0	4
ZC3H11A WILD-TYPE	221	184	99

Figure S160. Get High-res Image Gene #63: 'ZC3H11A MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

'ZC3H11A MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.336 (Fisher's exact test), Q value = 0.95

Table S621. Gene #63: 'ZC3H11A MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
ZC3H11A MUTATED	3	0	2
ZC3H11A WILD-TYPE	181	162	157

'ZC3H11A MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.0679 (Fisher's exact test), Q value = 0.48

Table S622. Gene #63: 'ZC3H11A MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
ZC3H11A MUTATED	1	0	1	3
ZC3H11A WILD-TYPE	89	138	187	86

'SLC6A3 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.703 (Fisher's exact test), Q value = 1

Table S623. Gene #64: 'SLC6A3 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	169	120	221
SLC6A3 MUTATED	3	3	3
SLC6A3 WILD-TYPE	166	117	218

'SLC6A3 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.877 (Fisher's exact test), Q value = 1

Table S624. Gene #64: 'SLC6A3 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	222	81	168	42
SLC6A3 MUTATED	4	2	3	0
SLC6A3 WILD-TYPE	218	79	165	42

'SLC6A3 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.326 (Fisher's exact test), Q value = 0.95

Table S625. Gene #64: 'SLC6A3 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	52	62	68	74
SLC6A3 MUTATED	0	1	4	2
SLC6A3 WILD-TYPE	52	61	64	72

'SLC6A3 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.0337 (Fisher's exact test), Q value = 0.31

Table S626. Gene #64: 'SLC6A3 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	67	131	58
SLC6A3 MUTATED	0	7	0
SLC6A3 WILD-TYPE	67	124	58

Figure S161. Get High-res Image Gene #64: 'SLC6A3 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

'SLC6A3 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.737 (Fisher's exact test), Q value = 1

Table S627. Gene #64: 'SLC6A3 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	132	109	109	133	30
SLC6A3 MUTATED	3	2	3	1	0
SLC6A3 WILD-TYPE	129	107	106	132	30

'SLC6A3 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.487 (Fisher's exact test), Q value = 1

Table S628. Gene #64: 'SLC6A3 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	134	71	36	66	91	41	74
SLC6A3 MUTATED	3	1	2	1	1	1	0
SLC6A3 WILD-TYPE	131	70	34	65	90	40	74

'SLC6A3 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.176 (Fisher's exact test), Q value = 0.8

Table S629. Gene #64: 'SLC6A3 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
SLC6A3 MUTATED	2	4	1	2
SLC6A3 WILD-TYPE	134	103	182	81

'SLC6A3 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.508 (Fisher's exact test), Q value = 1

Table S630. Gene #64: 'SLC6A3 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
SLC6A3 MUTATED	4	2	3
SLC6A3 WILD-TYPE	218	182	100

'SLC6A3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.705 (Fisher's exact test), Q value = 1

Table S631. Gene #64: 'SLC6A3 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
SLC6A3 MUTATED	3	2	4
SLC6A3 WILD-TYPE	181	160	155

'SLC6A3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.537 (Fisher's exact test), Q value = 1

Table S632. Gene #64: 'SLC6A3 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
SLC6A3 MUTATED	3	1	4	1
SLC6A3 WILD-TYPE	87	137	184	88

'TPTE2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.00429 (Fisher's exact test), Q value = 0.07

Table S633. Gene #65: 'TPTE2 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	169	120	221
TPTE2 MUTATED	5	0	0
TPTE2 WILD-TYPE	164	120	221

Figure S162. Get High-res Image Gene #65: 'TPTE2 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

'TPTE2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.166 (Fisher's exact test), Q value = 0.78

Table S634. Gene #65: 'TPTE2 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	222	81	168	42
TPTE2 MUTATED	5	0	0	0
TPTE2 WILD-TYPE	217	81	168	42

'TPTE2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.12 (Fisher's exact test), Q value = 0.65

Table S635. Gene #65: 'TPTE2 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	132	109	109	133	30
TPTE2 MUTATED	3	0	0	1	1
TPTE2 WILD-TYPE	129	109	109	132	29

'TPTE2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.33 (Fisher's exact test), Q value = 0.95

Table S636. Gene #65: 'TPTE2 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	134	71	36	66	91	41	74
TPTE2 MUTATED	4	0	0	1	0	0	0
TPTE2 WILD-TYPE	130	71	36	65	91	41	74

'TPTE2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S637. Gene #65: 'TPTE2 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
TPTE2 MUTATED	1	1	2	1
TPTE2 WILD-TYPE	135	106	181	82

'TPTE2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.848 (Fisher's exact test), Q value = 1

Table S638. Gene #65: 'TPTE2 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
TPTE2 MUTATED	3	1	1
TPTE2 WILD-TYPE	219	183	102

'TPTE2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.532 (Fisher's exact test), Q value = 1

Table S639. Gene #65: 'TPTE2 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
TPTE2 MUTATED	1	3	1
TPTE2 WILD-TYPE	183	159	158

'TPTE2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.927 (Fisher's exact test), Q value = 1

Table S640. Gene #65: 'TPTE2 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
TPTE2 MUTATED	1	2	2	0
TPTE2 WILD-TYPE	89	136	186	89

'C4BPA MUTATION STATUS' versus 'CN_CNMF'

P value = 0.329 (Fisher's exact test), Q value = 0.95

Table S641. Gene #66: 'C4BPA MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	169	120	221
C4BPA MUTATED	1	3	2
C4BPA WILD-TYPE	168	117	219

'C4BPA MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.3 (Fisher's exact test), Q value = 0.93

Table S642. Gene #66: 'C4BPA MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	222	81	168	42
C4BPA MUTATED	2	2	1	1
C4BPA WILD-TYPE	220	79	167	41

'C4BPA MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.904 (Fisher's exact test), Q value = 1

Table S643. Gene #66: 'C4BPA MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	132	109	109	133	30
C4BPA MUTATED	2	2	1	1	0
C4BPA WILD-TYPE	130	107	108	132	30

'C4BPA MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.382 (Fisher's exact test), Q value = 1

Table S644. Gene #66: 'C4BPA MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	134	71	36	66	91	41	74
C4BPA MUTATED	1	1	0	1	1	2	0
C4BPA WILD-TYPE	133	70	36	65	90	39	74

'C4BPA MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.731 (Fisher's exact test), Q value = 1

Table S645. Gene #66: 'C4BPA MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
C4BPA MUTATED	2	2	1	1
C4BPA WILD-TYPE	134	105	182	82

'C4BPA MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.507 (Fisher's exact test), Q value = 1

Table S646. Gene #66: 'C4BPA MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
C4BPA MUTATED	3	1	2
C4BPA WILD-TYPE	219	183	101

'C4BPA MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S647. Gene #66: 'C4BPA MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
C4BPA MUTATED	2	2	2
C4BPA WILD-TYPE	182	160	157

'C4BPA MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S648. Gene #66: 'C4BPA MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
C4BPA MUTATED	1	2	2	1
C4BPA WILD-TYPE	89	136	186	88

'MATK MUTATION STATUS' versus 'CN_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S649. Gene #67: 'MATK MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	169	120	221
MATK MUTATED	2	1	3
MATK WILD-TYPE	167	119	218

'MATK MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.915 (Fisher's exact test), Q value = 1

Table S650. Gene #67: 'MATK MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	222	81	168	42
MATK MUTATED	2	1	3	0
MATK WILD-TYPE	220	80	165	42

'MATK MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.842 (Fisher's exact test), Q value = 1

Table S651. Gene #67: 'MATK MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	52	62	68	74
MATK MUTATED	0	1	2	1
MATK WILD-TYPE	52	61	66	73

'MATK MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S652. Gene #67: 'MATK MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	67	131	58
MATK MUTATED	1	2	1
MATK WILD-TYPE	66	129	57

'MATK MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.236 (Fisher's exact test), Q value = 0.87

Table S653. Gene #67: 'MATK MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	132	109	109	133	30
MATK MUTATED	0	1	1	4	0
MATK WILD-TYPE	132	108	108	129	30

'MATK MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.167 (Fisher's exact test), Q value = 0.78

Table S654. Gene #67: 'MATK MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	134	71	36	66	91	41	74
MATK MUTATED	0	0	0	2	1	1	2
MATK WILD-TYPE	134	71	36	64	90	40	72

'MATK MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.429 (Fisher's exact test), Q value = 1

Table S655. Gene #67: 'MATK MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
MATK MUTATED	0	2	3	1
MATK WILD-TYPE	136	105	180	82

'MATK MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.866 (Fisher's exact test), Q value = 1

Table S656. Gene #67: 'MATK MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
MATK MUTATED	2	3	1
MATK WILD-TYPE	220	181	102

'MATK MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.456 (Fisher's exact test), Q value = 1

Table S657. Gene #67: 'MATK MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
MATK MUTATED	1	2	3
MATK WILD-TYPE	183	160	156

'MATK MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.412 (Fisher's exact test), Q value = 1

Table S658. Gene #67: 'MATK MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
MATK MUTATED	0	2	4	0
MATK WILD-TYPE	90	136	184	89

'SMOC1 MUTATION STATUS' versus 'CN_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S659. Gene #68: 'SMOC1 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	169	120	221
SMOC1 MUTATED	1	1	1
SMOC1 WILD-TYPE	168	119	220

'SMOC1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S660. Gene #68: 'SMOC1 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	222	81	168	42
SMOC1 MUTATED	2	0	1	0
SMOC1 WILD-TYPE	220	81	167	42

'SMOC1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S661. Gene #68: 'SMOC1 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	132	109	109	133	30
SMOC1 MUTATED	1	1	0	1	0
SMOC1 WILD-TYPE	131	108	109	132	30

'SMOC1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.817 (Fisher's exact test), Q value = 1

Table S662. Gene #68: 'SMOC1 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	134	71	36	66	91	41	74
SMOC1 MUTATED	2	0	0	0	0	0	1
SMOC1 WILD-TYPE	132	71	36	66	91	41	73

'SMOC1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.598 (Fisher's exact test), Q value = 1

Table S663. Gene #68: 'SMOC1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
SMOC1 MUTATED	2	0	1	0
SMOC1 WILD-TYPE	134	107	182	83

'SMOC1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S664. Gene #68: 'SMOC1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
SMOC1 MUTATED	2	1	0
SMOC1 WILD-TYPE	220	183	103

'SMOC1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.652 (Fisher's exact test), Q value = 1

Table S665. Gene #68: 'SMOC1 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
SMOC1 MUTATED	2	0	1
SMOC1 WILD-TYPE	182	162	158

'SMOC1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.185 (Fisher's exact test), Q value = 0.81

Table S666. Gene #68: 'SMOC1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
SMOC1 MUTATED	2	0	1	0
SMOC1 WILD-TYPE	88	138	187	89

'NAP1L2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.687 (Fisher's exact test), Q value = 1

Table S667. Gene #69: 'NAP1L2 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	169	120	221
NAP1L2 MUTATED	2	0	2
NAP1L2 WILD-TYPE	167	120	219

'NAP1L2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S668. Gene #69: 'NAP1L2 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	222	81	168	42
NAP1L2 MUTATED	2	0	2	0
NAP1L2 WILD-TYPE	220	81	166	42

'NAP1L2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.381 (Fisher's exact test), Q value = 1

Table S669. Gene #69: 'NAP1L2 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	132	109	109	133	30
NAP1L2 MUTATED	2	0	2	0	0
NAP1L2 WILD-TYPE	130	109	107	133	30

'NAP1L2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0682 (Fisher's exact test), Q value = 0.48

Table S670. Gene #69: 'NAP1L2 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	134	71	36	66	91	41	74
NAP1L2 MUTATED	2	0	2	0	0	0	0
NAP1L2 WILD-TYPE	132	71	34	66	91	41	74

'NAP1L2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S671. Gene #69: 'NAP1L2 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
NAP1L2 MUTATED	1	1	2	0
NAP1L2 WILD-TYPE	135	106	181	83

'NAP1L2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.832 (Fisher's exact test), Q value = 1

Table S672. Gene #69: 'NAP1L2 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
NAP1L2 MUTATED	2	2	0
NAP1L2 WILD-TYPE	220	182	103

'NAP1L2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S673. Gene #69: 'NAP1L2 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
NAP1L2 MUTATED	2	1	1
NAP1L2 WILD-TYPE	182	161	158

'NAP1L2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S674. Gene #69: 'NAP1L2 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
NAP1L2 MUTATED	1	1	2	0
NAP1L2 WILD-TYPE	89	137	186	89

'CD99L2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.362 (Fisher's exact test), Q value = 0.98

Table S675. Gene #70: 'CD99L2 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	169	120	221
CD99L2 MUTATED	0	1	3
CD99L2 WILD-TYPE	169	119	218

'CD99L2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.123 (Fisher's exact test), Q value = 0.66

Table S676. Gene #70: 'CD99L2 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	222	81	168	42
CD99L2 MUTATED	0	1	2	1
CD99L2 WILD-TYPE	222	80	166	41

'CD99L2 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.626 (Fisher's exact test), Q value = 1

Table S677. Gene #70: 'CD99L2 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	52	62	68	74
CD99L2 MUTATED	0	0	1	2
CD99L2 WILD-TYPE	52	62	67	72

'CD99L2 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.608 (Fisher's exact test), Q value = 1

Table S678. Gene #70: 'CD99L2 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	67	131	58
CD99L2 MUTATED	0	2	1
CD99L2 WILD-TYPE	67	129	57

'CD99L2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.603 (Fisher's exact test), Q value = 1

Table S679. Gene #70: 'CD99L2 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	132	109	109	133	30
CD99L2 MUTATED	0	1	2	1	0
CD99L2 WILD-TYPE	132	108	107	132	30

'CD99L2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.229 (Fisher's exact test), Q value = 0.86

Table S680. Gene #70: 'CD99L2 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	134	71	36	66	91	41	74
CD99L2 MUTATED	0	0	0	0	2	1	1
CD99L2 WILD-TYPE	134	71	36	66	89	40	73

'CD99L2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.217 (Fisher's exact test), Q value = 0.86

Table S681. Gene #70: 'CD99L2 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
CD99L2 MUTATED	0	1	1	2
CD99L2 WILD-TYPE	136	106	182	81

'CD99L2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S682. Gene #70: 'CD99L2 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
CD99L2 MUTATED	2	1	1
CD99L2 WILD-TYPE	220	183	102

'CD99L2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.697 (Fisher's exact test), Q value = 1

Table S683. Gene #70: 'CD99L2 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
CD99L2 MUTATED	1	1	2
CD99L2 WILD-TYPE	183	161	157

'CD99L2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.58 (Fisher's exact test), Q value = 1

Table S684. Gene #70: 'CD99L2 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
CD99L2 MUTATED	0	1	3	0
CD99L2 WILD-TYPE	90	137	185	89

'SELE MUTATION STATUS' versus 'CN_CNMF'

P value = 0.278 (Fisher's exact test), Q value = 0.9

Table S685. Gene #71: 'SELE MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	169	120	221
SELE MUTATED	2	3	1
SELE WILD-TYPE	167	117	220

'SELE MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.236 (Fisher's exact test), Q value = 0.87

Table S686. Gene #71: 'SELE MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	222	81	168	42
SELE MUTATED	2	3	1	0
SELE WILD-TYPE	220	78	167	42

'SELE MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.344 (Fisher's exact test), Q value = 0.95

Table S687. Gene #71: 'SELE MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	52	62	68	74
SELE MUTATED	2	1	1	0
SELE WILD-TYPE	50	61	67	74

'SELE MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.55 (Fisher's exact test), Q value = 1

Table S688. Gene #71: 'SELE MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	67	131	58
SELE MUTATED	2	2	0
SELE WILD-TYPE	65	129	58

'SELE MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.7 (Fisher's exact test), Q value = 1

Table S689. Gene #71: 'SELE MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	132	109	109	133	30
SELE MUTATED	1	3	1	1	0
SELE WILD-TYPE	131	106	108	132	30

'SELE MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.38 (Fisher's exact test), Q value = 1

Table S690. Gene #71: 'SELE MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	134	71	36	66	91	41	74
SELE MUTATED	1	1	0	1	1	2	0
SELE WILD-TYPE	133	70	36	65	90	39	74

'SELE MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.732 (Fisher's exact test), Q value = 1

Table S691. Gene #71: 'SELE MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
SELE MUTATED	2	2	1	1
SELE WILD-TYPE	134	105	182	82

'SELE MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0654 (Fisher's exact test), Q value = 0.47

Table S692. Gene #71: 'SELE MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
SELE MUTATED	3	0	3
SELE WILD-TYPE	219	184	100

'SELE MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.453 (Fisher's exact test), Q value = 1

Table S693. Gene #71: 'SELE MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
SELE MUTATED	1	2	3
SELE WILD-TYPE	183	160	156

'SELE MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S694. Gene #71: 'SELE MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
SELE MUTATED	1	2	2	1
SELE WILD-TYPE	89	136	186	88

'TMEM184A MUTATION STATUS' versus 'CN_CNMF'

P value = 0.464 (Fisher's exact test), Q value = 1

Table S695. Gene #72: 'TMEM184A MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	169	120	221
TMEM184A MUTATED	0	1	2
TMEM184A WILD-TYPE	169	119	219

'TMEM184A MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.302 (Fisher's exact test), Q value = 0.93

Table S696. Gene #72: 'TMEM184A MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	222	81	168	42
TMEM184A MUTATED	0	1	2	0
TMEM184A WILD-TYPE	222	80	166	42

'TMEM184A MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.585 (Fisher's exact test), Q value = 1

Table S697. Gene #72: 'TMEM184A MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	132	109	109	133	30
TMEM184A MUTATED	0	1	0	2	0
TMEM184A WILD-TYPE	132	108	109	131	30

'TMEM184A MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.175 (Fisher's exact test), Q value = 0.8

Table S698. Gene #72: 'TMEM184A MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	134	71	36	66	91	41	74
TMEM184A MUTATED	0	1	0	0	0	0	2
TMEM184A WILD-TYPE	134	70	36	66	91	41	72

'TMEM184A MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.877 (Fisher's exact test), Q value = 1

Table S699. Gene #72: 'TMEM184A MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
TMEM184A MUTATED	1	0	2	0
TMEM184A WILD-TYPE	135	107	181	83

'TMEM184A MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.231 (Fisher's exact test), Q value = 0.86

Table S700. Gene #72: 'TMEM184A MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
TMEM184A MUTATED	0	2	1
TMEM184A WILD-TYPE	222	182	102

'TMEM184A MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.415 (Fisher's exact test), Q value = 1

Table S701. Gene #72: 'TMEM184A MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
TMEM184A MUTATED	1	0	2
TMEM184A WILD-TYPE	183	162	157

'TMEM184A MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.509 (Fisher's exact test), Q value = 1

Table S702. Gene #72: 'TMEM184A MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
TMEM184A MUTATED	0	0	2	1
TMEM184A WILD-TYPE	90	138	186	88

'FHOD1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.671 (Fisher's exact test), Q value = 1

Table S703. Gene #73: 'FHOD1 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	169	120	221
FHOD1 MUTATED	1	2	3
FHOD1 WILD-TYPE	168	118	218

'FHOD1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.277 (Fisher's exact test), Q value = 0.9

Table S704. Gene #73: 'FHOD1 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	222	81	168	42
FHOD1 MUTATED	1	2	3	0
FHOD1 WILD-TYPE	221	79	165	42

'FHOD1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S705. Gene #73: 'FHOD1 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	52	62	68	74
FHOD1 MUTATED	0	1	1	1
FHOD1 WILD-TYPE	52	61	67	73

'FHOD1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.611 (Fisher's exact test), Q value = 1

Table S706. Gene #73: 'FHOD1 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	67	131	58
FHOD1 MUTATED	0	2	1
FHOD1 WILD-TYPE	67	129	57

'FHOD1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.963 (Fisher's exact test), Q value = 1

Table S707. Gene #73: 'FHOD1 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	132	109	109	133	30
FHOD1 MUTATED	1	2	1	2	0
FHOD1 WILD-TYPE	131	107	108	131	30

'FHOD1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.82 (Fisher's exact test), Q value = 1

Table S708. Gene #73: 'FHOD1 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	134	71	36	66	91	41	74
FHOD1 MUTATED	1	1	0	0	2	1	1
FHOD1 WILD-TYPE	133	70	36	66	89	40	73

'FHOD1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.892 (Fisher's exact test), Q value = 1

Table S709. Gene #73: 'FHOD1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
FHOD1 MUTATED	1	2	2	1
FHOD1 WILD-TYPE	135	105	181	82

'FHOD1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.756 (Fisher's exact test), Q value = 1

Table S710. Gene #73: 'FHOD1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
FHOD1 MUTATED	2	2	2
FHOD1 WILD-TYPE	220	182	101

'FHOD1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.457 (Fisher's exact test), Q value = 1

Table S711. Gene #73: 'FHOD1 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
FHOD1 MUTATED	1	2	3
FHOD1 WILD-TYPE	183	160	156

'FHOD1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.698 (Fisher's exact test), Q value = 1

Table S712. Gene #73: 'FHOD1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
FHOD1 MUTATED	0	3	2	1
FHOD1 WILD-TYPE	90	135	186	88

'HTR3A MUTATION STATUS' versus 'CN_CNMF'

P value = 0.617 (Fisher's exact test), Q value = 1

Table S713. Gene #74: 'HTR3A MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	169	120	221
HTR3A MUTATED	1	2	4
HTR3A WILD-TYPE	168	118	217

'HTR3A MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.153 (Fisher's exact test), Q value = 0.76

Table S714. Gene #74: 'HTR3A MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	222	81	168	42
HTR3A MUTATED	1	3	3	0
HTR3A WILD-TYPE	221	78	165	42

'HTR3A MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.256 (Fisher's exact test), Q value = 0.89

Table S715. Gene #74: 'HTR3A MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	52	62	68	74
HTR3A MUTATED	0	2	2	0
HTR3A WILD-TYPE	52	60	66	74

'HTR3A MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.809 (Fisher's exact test), Q value = 1

Table S716. Gene #74: 'HTR3A MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	67	131	58
HTR3A MUTATED	1	3	0
HTR3A WILD-TYPE	66	128	58

'HTR3A MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.659 (Fisher's exact test), Q value = 1

Table S717. Gene #74: 'HTR3A MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	132	109	109	133	30
HTR3A MUTATED	1	3	2	1	0
HTR3A WILD-TYPE	131	106	107	132	30

'HTR3A MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.382 (Fisher's exact test), Q value = 1

Table S718. Gene #74: 'HTR3A MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	134	71	36	66	91	41	74
HTR3A MUTATED	1	2	1	0	2	1	0
HTR3A WILD-TYPE	133	69	35	66	89	40	74

'HTR3A MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.17 (Fisher's exact test), Q value = 0.79

Table S719. Gene #74: 'HTR3A MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
HTR3A MUTATED	1	2	1	3
HTR3A WILD-TYPE	135	105	182	80

'HTR3A MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.243 (Fisher's exact test), Q value = 0.88

Table S720. Gene #74: 'HTR3A MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
HTR3A MUTATED	3	1	3
HTR3A WILD-TYPE	219	183	100

'HTR3A MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.574 (Fisher's exact test), Q value = 1

Table S721. Gene #74: 'HTR3A MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
HTR3A MUTATED	4	2	1
HTR3A WILD-TYPE	180	160	158

'HTR3A MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.871 (Fisher's exact test), Q value = 1

Table S722. Gene #74: 'HTR3A MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
HTR3A MUTATED	1	2	2	2
HTR3A WILD-TYPE	89	136	186	87

'RB1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.00023 (Fisher's exact test), Q value = 0.0058

Table S723. Gene #75: 'RB1 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	169	120	221
RB1 MUTATED	0	6	0
RB1 WILD-TYPE	169	114	221

Figure S163. Get High-res Image Gene #75: 'RB1 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

'RB1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.00084 (Fisher's exact test), Q value = 0.018

Table S724. Gene #75: 'RB1 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	222	81	168	42
RB1 MUTATED	0	5	1	0
RB1 WILD-TYPE	222	76	167	42

Figure S164. Get High-res Image Gene #75: 'RB1 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

'RB1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.487 (Fisher's exact test), Q value = 1

Table S725. Gene #75: 'RB1 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	52	62	68	74
RB1 MUTATED	1	2	1	0
RB1 WILD-TYPE	51	60	67	74

'RB1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.81 (Fisher's exact test), Q value = 1

Table S726. Gene #75: 'RB1 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	67	131	58
RB1 MUTATED	1	3	0
RB1 WILD-TYPE	66	128	58

'RB1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0165 (Fisher's exact test), Q value = 0.2

Table S727. Gene #75: 'RB1 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	132	109	109	133	30
RB1 MUTATED	0	4	1	0	1
RB1 WILD-TYPE	132	105	108	133	29

Figure S165. Get High-res Image Gene #75: 'RB1 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

'RB1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0959 (Fisher's exact test), Q value = 0.57

Table S728. Gene #75: 'RB1 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	134	71	36	66	91	41	74
RB1 MUTATED	0	3	0	1	1	1	0
RB1 WILD-TYPE	134	68	36	65	90	40	74

'RB1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.599 (Fisher's exact test), Q value = 1

Table S729. Gene #75: 'RB1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
RB1 MUTATED	3	1	1	1
RB1 WILD-TYPE	133	106	182	82

'RB1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0327 (Fisher's exact test), Q value = 0.3

Table S730. Gene #75: 'RB1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
RB1 MUTATED	1	1	4
RB1 WILD-TYPE	221	183	99

Figure S166. Get High-res Image Gene #75: 'RB1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

'RB1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.782 (Fisher's exact test), Q value = 1

Table S731. Gene #75: 'RB1 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
RB1 MUTATED	3	1	2
RB1 WILD-TYPE	181	161	157

'RB1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.247 (Fisher's exact test), Q value = 0.88

Table S732. Gene #75: 'RB1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
RB1 MUTATED	0	1	2	3
RB1 WILD-TYPE	90	137	186	86

'FGD6 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.221 (Fisher's exact test), Q value = 0.86

Table S733. Gene #76: 'FGD6 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	169	120	221
FGD6 MUTATED	0	2	2
FGD6 WILD-TYPE	169	118	219

'FGD6 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.881 (Fisher's exact test), Q value = 1

Table S734. Gene #76: 'FGD6 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	222	81	168	42
FGD6 MUTATED	2	1	1	0
FGD6 WILD-TYPE	220	80	167	42

'FGD6 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.255 (Fisher's exact test), Q value = 0.89

Table S735. Gene #76: 'FGD6 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	52	62	68	74
FGD6 MUTATED	0	2	2	0
FGD6 WILD-TYPE	52	60	66	74

'FGD6 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.182 (Fisher's exact test), Q value = 0.81

Table S736. Gene #76: 'FGD6 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	67	131	58
FGD6 MUTATED	0	4	0
FGD6 WILD-TYPE	67	127	58

'FGD6 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.542 (Fisher's exact test), Q value = 1

Table S737. Gene #76: 'FGD6 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	132	109	109	133	30
FGD6 MUTATED	1	2	1	0	0
FGD6 WILD-TYPE	131	107	108	133	30

'FGD6 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.723 (Fisher's exact test), Q value = 1

Table S738. Gene #76: 'FGD6 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	134	71	36	66	91	41	74
FGD6 MUTATED	2	0	0	0	1	1	0
FGD6 WILD-TYPE	132	71	36	66	90	40	74

'FGD6 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.277 (Fisher's exact test), Q value = 0.9

Table S739. Gene #76: 'FGD6 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
FGD6 MUTATED	2	1	0	1
FGD6 WILD-TYPE	134	106	183	82

'FGD6 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.263 (Fisher's exact test), Q value = 0.89

Table S740. Gene #76: 'FGD6 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
FGD6 MUTATED	3	0	1
FGD6 WILD-TYPE	219	184	102

'FGD6 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S741. Gene #76: 'FGD6 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
FGD6 MUTATED	2	1	1
FGD6 WILD-TYPE	182	161	158

'FGD6 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S742. Gene #76: 'FGD6 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
FGD6 MUTATED	1	1	2	0
FGD6 WILD-TYPE	89	137	186	89

'CD72 MUTATION STATUS' versus 'CN_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S743. Gene #77: 'CD72 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	169	120	221
CD72 MUTATED	1	1	1
CD72 WILD-TYPE	168	119	220

'CD72 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.541 (Fisher's exact test), Q value = 1

Table S744. Gene #77: 'CD72 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	222	81	168	42
CD72 MUTATED	2	1	0	0
CD72 WILD-TYPE	220	80	168	42

'CD72 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.343 (Fisher's exact test), Q value = 0.95

Table S745. Gene #77: 'CD72 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	132	109	109	133	30
CD72 MUTATED	1	2	0	0	0
CD72 WILD-TYPE	131	107	109	133	30

'CD72 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.511 (Fisher's exact test), Q value = 1

Table S746. Gene #77: 'CD72 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	134	71	36	66	91	41	74
CD72 MUTATED	1	1	0	0	0	1	0
CD72 WILD-TYPE	133	70	36	66	91	40	74

'CD72 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.19 (Fisher's exact test), Q value = 0.83

Table S747. Gene #77: 'CD72 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
CD72 MUTATED	1	2	0	0
CD72 WILD-TYPE	135	105	183	83

'CD72 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.152 (Fisher's exact test), Q value = 0.76

Table S748. Gene #77: 'CD72 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
CD72 MUTATED	1	0	2
CD72 WILD-TYPE	221	184	101

'CD72 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.11 (Fisher's exact test), Q value = 0.63

Table S749. Gene #77: 'CD72 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
CD72 MUTATED	3	0	0
CD72 WILD-TYPE	181	162	159

'CD72 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.0275 (Fisher's exact test), Q value = 0.27

Table S750. Gene #77: 'CD72 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
CD72 MUTATED	1	0	0	2
CD72 WILD-TYPE	89	138	188	87

Figure S167. Get High-res Image Gene #77: 'CD72 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

'NKPD1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.609 (Fisher's exact test), Q value = 1

Table S751. Gene #78: 'NKPD1 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	169	120	221
NKPD1 MUTATED	2	0	1
NKPD1 WILD-TYPE	167	120	220

'NKPD1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S752. Gene #78: 'NKPD1 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	222	81	168	42
NKPD1 MUTATED	2	0	1	0
NKPD1 WILD-TYPE	220	81	167	42

'NKPD1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S753. Gene #78: 'NKPD1 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	132	109	109	133	30
NKPD1 MUTATED	1	1	0	1	0
NKPD1 WILD-TYPE	131	108	109	132	30

'NKPD1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.547 (Fisher's exact test), Q value = 1

Table S754. Gene #78: 'NKPD1 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	134	71	36	66	91	41	74
NKPD1 MUTATED	1	0	0	0	0	1	1
NKPD1 WILD-TYPE	133	71	36	66	91	40	73

'NKPD1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.681 (Fisher's exact test), Q value = 1

Table S755. Gene #78: 'NKPD1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
NKPD1 MUTATED	0	1	2	0
NKPD1 WILD-TYPE	136	106	181	83

'NKPD1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.794 (Fisher's exact test), Q value = 1

Table S756. Gene #78: 'NKPD1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
NKPD1 MUTATED	1	1	1
NKPD1 WILD-TYPE	221	183	102

'NKPD1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.208 (Fisher's exact test), Q value = 0.85

Table S757. Gene #78: 'NKPD1 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
NKPD1 MUTATED	0	1	2
NKPD1 WILD-TYPE	184	161	157

'NKPD1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.776 (Fisher's exact test), Q value = 1

Table S758. Gene #78: 'NKPD1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
NKPD1 MUTATED	0	1	1	1
NKPD1 WILD-TYPE	90	137	187	88

'MTMR1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.055 (Fisher's exact test), Q value = 0.42

Table S759. Gene #79: 'MTMR1 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	169	120	221
MTMR1 MUTATED	0	3	1
MTMR1 WILD-TYPE	169	117	220

'MTMR1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.306 (Fisher's exact test), Q value = 0.93

Table S760. Gene #79: 'MTMR1 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	222	81	168	42
MTMR1 MUTATED	1	2	1	0
MTMR1 WILD-TYPE	221	79	167	42

'MTMR1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S761. Gene #79: 'MTMR1 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	132	109	109	133	30
MTMR1 MUTATED	1	1	1	1	0
MTMR1 WILD-TYPE	131	108	108	132	30

'MTMR1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0232 (Fisher's exact test), Q value = 0.25

Table S762. Gene #79: 'MTMR1 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	134	71	36	66	91	41	74
MTMR1 MUTATED	0	0	1	2	0	1	0
MTMR1 WILD-TYPE	134	71	35	64	91	40	74

Figure S168. Get High-res Image Gene #79: 'MTMR1 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'MTMR1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.438 (Fisher's exact test), Q value = 1

Table S763. Gene #79: 'MTMR1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
MTMR1 MUTATED	0	1	3	0
MTMR1 WILD-TYPE	136	106	180	83

'MTMR1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0756 (Fisher's exact test), Q value = 0.51

Table S764. Gene #79: 'MTMR1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
MTMR1 MUTATED	0	2	2
MTMR1 WILD-TYPE	222	182	101

'MTMR1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.332 (Fisher's exact test), Q value = 0.95

Table S765. Gene #79: 'MTMR1 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
MTMR1 MUTATED	0	2	2
MTMR1 WILD-TYPE	184	160	157

'MTMR1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.918 (Fisher's exact test), Q value = 1

Table S766. Gene #79: 'MTMR1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
MTMR1 MUTATED	0	1	2	1
MTMR1 WILD-TYPE	90	137	186	88

'GPR133 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.457 (Fisher's exact test), Q value = 1

Table S767. Gene #80: 'GPR133 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	169	120	221
GPR133 MUTATED	1	2	1
GPR133 WILD-TYPE	168	118	220

'GPR133 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.306 (Fisher's exact test), Q value = 0.93

Table S768. Gene #80: 'GPR133 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	222	81	168	42
GPR133 MUTATED	1	2	1	0
GPR133 WILD-TYPE	221	79	167	42

'GPR133 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0243 (Fisher's exact test), Q value = 0.25

Table S769. Gene #80: 'GPR133 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	132	109	109	133	30
GPR133 MUTATED	0	1	0	1	2
GPR133 WILD-TYPE	132	108	109	132	28

Figure S169. Get High-res Image Gene #80: 'GPR133 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

'GPR133 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.584 (Fisher's exact test), Q value = 1

Table S770. Gene #80: 'GPR133 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	134	71	36	66	91	41	74
GPR133 MUTATED	1	0	0	1	0	1	1
GPR133 WILD-TYPE	133	71	36	65	91	40	73

'GPR133 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S771. Gene #80: 'GPR133 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
GPR133 MUTATED	1	1	2	0
GPR133 WILD-TYPE	135	106	181	83

'GPR133 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.685 (Fisher's exact test), Q value = 1

Table S772. Gene #80: 'GPR133 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
GPR133 MUTATED	1	2	1
GPR133 WILD-TYPE	221	182	102

'GPR133 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.0759 (Fisher's exact test), Q value = 0.51

Table S773. Gene #80: 'GPR133 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
GPR133 MUTATED	0	1	3
GPR133 WILD-TYPE	184	161	156

'GPR133 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.396 (Fisher's exact test), Q value = 1

Table S774. Gene #80: 'GPR133 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
GPR133 MUTATED	1	0	3	0
GPR133 WILD-TYPE	89	138	185	89

'CNOT4 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.253 (Fisher's exact test), Q value = 0.89

Table S775. Gene #81: 'CNOT4 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	169	120	221
CNOT4 MUTATED	0	2	3
CNOT4 WILD-TYPE	169	118	218

'CNOT4 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.559 (Fisher's exact test), Q value = 1

Table S776. Gene #81: 'CNOT4 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	222	81	168	42
CNOT4 MUTATED	2	1	1	1
CNOT4 WILD-TYPE	220	80	167	41

'CNOT4 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.888 (Fisher's exact test), Q value = 1

Table S777. Gene #81: 'CNOT4 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	52	62	68	74
CNOT4 MUTATED	1	0	1	1
CNOT4 WILD-TYPE	51	62	67	73

'CNOT4 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.61 (Fisher's exact test), Q value = 1

Table S778. Gene #81: 'CNOT4 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	67	131	58
CNOT4 MUTATED	0	2	1
CNOT4 WILD-TYPE	67	129	57

'CNOT4 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.3 (Fisher's exact test), Q value = 0.93

Table S779. Gene #81: 'CNOT4 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	132	109	109	133	30
CNOT4 MUTATED	0	3	1	1	0
CNOT4 WILD-TYPE	132	106	108	132	30

'CNOT4 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00959 (Fisher's exact test), Q value = 0.13

Table S780. Gene #81: 'CNOT4 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	134	71	36	66	91	41	74
CNOT4 MUTATED	0	0	0	0	1	3	1
CNOT4 WILD-TYPE	134	71	36	66	90	38	73

Figure S170. Get High-res Image Gene #81: 'CNOT4 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'CNOT4 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.115 (Fisher's exact test), Q value = 0.64

Table S781. Gene #81: 'CNOT4 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
CNOT4 MUTATED	0	3	1	1
CNOT4 WILD-TYPE	136	104	182	82

'CNOT4 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.117 (Fisher's exact test), Q value = 0.64

Table S782. Gene #81: 'CNOT4 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
CNOT4 MUTATED	1	1	3
CNOT4 WILD-TYPE	221	183	100

'CNOT4 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.335 (Fisher's exact test), Q value = 0.95

Table S783. Gene #81: 'CNOT4 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
CNOT4 MUTATED	3	0	2
CNOT4 WILD-TYPE	181	162	157

'CNOT4 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.451 (Fisher's exact test), Q value = 1

Table S784. Gene #81: 'CNOT4 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
CNOT4 MUTATED	0	3	2	0
CNOT4 WILD-TYPE	90	135	186	89

'ZBTB20 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.012 (Fisher's exact test), Q value = 0.15

Table S785. Gene #82: 'ZBTB20 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	169	120	221
ZBTB20 MUTATED	3	2	16
ZBTB20 WILD-TYPE	166	118	205

Figure S171. Get High-res Image Gene #82: 'ZBTB20 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

'ZBTB20 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.00066 (Fisher's exact test), Q value = 0.015

Table S786. Gene #82: 'ZBTB20 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	222	81	168	42
ZBTB20 MUTATED	3	2	16	0
ZBTB20 WILD-TYPE	219	79	152	42

Figure S172. Get High-res Image Gene #82: 'ZBTB20 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

'ZBTB20 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.672 (Fisher's exact test), Q value = 1

Table S787. Gene #82: 'ZBTB20 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	52	62	68	74
ZBTB20 MUTATED	3	1	3	4
ZBTB20 WILD-TYPE	49	61	65	70

'ZBTB20 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.516 (Fisher's exact test), Q value = 1

Table S788. Gene #82: 'ZBTB20 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	67	131	58
ZBTB20 MUTATED	4	4	3
ZBTB20 WILD-TYPE	63	127	55

'ZBTB20 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0129 (Fisher's exact test), Q value = 0.16

Table S789. Gene #82: 'ZBTB20 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	132	109	109	133	30
ZBTB20 MUTATED	1	2	5	11	2
ZBTB20 WILD-TYPE	131	107	104	122	28

Figure S173. Get High-res Image Gene #82: 'ZBTB20 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

'ZBTB20 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0038 (Fisher's exact test), Q value = 0.063

Table S790. Gene #82: 'ZBTB20 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	134	71	36	66	91	41	74
ZBTB20 MUTATED	1	0	4	2	6	2	6
ZBTB20 WILD-TYPE	133	71	32	64	85	39	68

Figure S174. Get High-res Image Gene #82: 'ZBTB20 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'ZBTB20 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.159 (Fisher's exact test), Q value = 0.77

Table S791. Gene #82: 'ZBTB20 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
ZBTB20 MUTATED	3	2	12	4
ZBTB20 WILD-TYPE	133	105	171	79

'ZBTB20 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0207 (Fisher's exact test), Q value = 0.23

Table S792. Gene #82: 'ZBTB20 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
ZBTB20 MUTATED	5	14	2
ZBTB20 WILD-TYPE	217	170	101

Figure S175. Get High-res Image Gene #82: 'ZBTB20 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

'ZBTB20 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.0405 (Fisher's exact test), Q value = 0.35

Table S793. Gene #82: 'ZBTB20 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
ZBTB20 MUTATED	3	7	11
ZBTB20 WILD-TYPE	181	155	148

Figure S176. Get High-res Image Gene #82: 'ZBTB20 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

'ZBTB20 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.0326 (Fisher's exact test), Q value = 0.3

Table S794. Gene #82: 'ZBTB20 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
ZBTB20 MUTATED	1	5	14	1
ZBTB20 WILD-TYPE	89	133	174	88

Figure S177. Get High-res Image Gene #82: 'ZBTB20 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

'ROBO3 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.621 (Fisher's exact test), Q value = 1

Table S795. Gene #83: 'ROBO3 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	169	120	221
ROBO3 MUTATED	2	0	3
ROBO3 WILD-TYPE	167	120	218

'ROBO3 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.903 (Fisher's exact test), Q value = 1

Table S796. Gene #83: 'ROBO3 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	222	81	168	42
ROBO3 MUTATED	3	0	2	0
ROBO3 WILD-TYPE	219	81	166	42

'ROBO3 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.828 (Fisher's exact test), Q value = 1

Table S797. Gene #83: 'ROBO3 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	132	109	109	133	30
ROBO3 MUTATED	2	0	1	2	0
ROBO3 WILD-TYPE	130	109	108	131	30

'ROBO3 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.71 (Fisher's exact test), Q value = 1

Table S798. Gene #83: 'ROBO3 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	134	71	36	66	91	41	74
ROBO3 MUTATED	2	0	1	1	1	0	0
ROBO3 WILD-TYPE	132	71	35	65	90	41	74

'ROBO3 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.401 (Fisher's exact test), Q value = 1

Table S799. Gene #83: 'ROBO3 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
ROBO3 MUTATED	1	0	2	2
ROBO3 WILD-TYPE	135	107	181	81

'ROBO3 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.289 (Fisher's exact test), Q value = 0.92

Table S800. Gene #83: 'ROBO3 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
ROBO3 MUTATED	4	1	0
ROBO3 WILD-TYPE	218	183	103

'ROBO3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S801. Gene #83: 'ROBO3 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
ROBO3 MUTATED	2	2	1
ROBO3 WILD-TYPE	182	160	158

'ROBO3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.929 (Fisher's exact test), Q value = 1

Table S802. Gene #83: 'ROBO3 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
ROBO3 MUTATED	1	2	2	0
ROBO3 WILD-TYPE	89	136	186	89

'PDE8A MUTATION STATUS' versus 'CN_CNMF'

P value = 0.282 (Fisher's exact test), Q value = 0.91

Table S803. Gene #84: 'PDE8A MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	169	120	221
PDE8A MUTATED	2	3	1
PDE8A WILD-TYPE	167	117	220

'PDE8A MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.238 (Fisher's exact test), Q value = 0.87

Table S804. Gene #84: 'PDE8A MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	222	81	168	42
PDE8A MUTATED	2	3	1	0
PDE8A WILD-TYPE	220	78	167	42

'PDE8A MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.841 (Fisher's exact test), Q value = 1

Table S805. Gene #84: 'PDE8A MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	52	62	68	74
PDE8A MUTATED	0	1	2	1
PDE8A WILD-TYPE	52	61	66	73

'PDE8A MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.671 (Fisher's exact test), Q value = 1

Table S806. Gene #84: 'PDE8A MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	67	131	58
PDE8A MUTATED	0	3	1
PDE8A WILD-TYPE	67	128	57

'PDE8A MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.7 (Fisher's exact test), Q value = 1

Table S807. Gene #84: 'PDE8A MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	132	109	109	133	30
PDE8A MUTATED	1	3	1	1	0
PDE8A WILD-TYPE	131	106	108	132	30

'PDE8A MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.703 (Fisher's exact test), Q value = 1

Table S808. Gene #84: 'PDE8A MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	134	71	36	66	91	41	74
PDE8A MUTATED	1	2	0	0	1	1	1
PDE8A WILD-TYPE	133	69	36	66	90	40	73

'PDE8A MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.731 (Fisher's exact test), Q value = 1

Table S809. Gene #84: 'PDE8A MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
PDE8A MUTATED	2	2	1	1
PDE8A WILD-TYPE	134	105	182	82

'PDE8A MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.216 (Fisher's exact test), Q value = 0.86

Table S810. Gene #84: 'PDE8A MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
PDE8A MUTATED	2	1	3
PDE8A WILD-TYPE	220	183	100

'PDE8A MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.781 (Fisher's exact test), Q value = 1

Table S811. Gene #84: 'PDE8A MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
PDE8A MUTATED	3	1	2
PDE8A WILD-TYPE	181	161	157

'PDE8A MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.767 (Fisher's exact test), Q value = 1

Table S812. Gene #84: 'PDE8A MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
PDE8A MUTATED	1	1	2	2
PDE8A WILD-TYPE	89	137	186	87

'EEF1D MUTATION STATUS' versus 'CN_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S813. Gene #85: 'EEF1D MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	169	120	221
EEF1D MUTATED	1	1	1
EEF1D WILD-TYPE	168	119	220

'EEF1D MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.539 (Fisher's exact test), Q value = 1

Table S814. Gene #85: 'EEF1D MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	222	81	168	42
EEF1D MUTATED	2	1	0	0
EEF1D WILD-TYPE	220	80	168	42

'EEF1D MUTATION STATUS' versus 'RPPA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S815. Gene #85: 'EEF1D MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	52	62	68	74
EEF1D MUTATED	0	1	1	1
EEF1D WILD-TYPE	52	61	67	73

'EEF1D MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.611 (Fisher's exact test), Q value = 1

Table S816. Gene #85: 'EEF1D MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	67	131	58
EEF1D MUTATED	0	2	1
EEF1D WILD-TYPE	67	129	57

'EEF1D MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.414 (Fisher's exact test), Q value = 1

Table S817. Gene #85: 'EEF1D MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	132	109	109	133	30
EEF1D MUTATED	0	2	0	1	0
EEF1D WILD-TYPE	132	107	109	132	30

'EEF1D MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.548 (Fisher's exact test), Q value = 1

Table S818. Gene #85: 'EEF1D MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	134	71	36	66	91	41	74
EEF1D MUTATED	1	0	0	0	0	1	1
EEF1D WILD-TYPE	133	71	36	66	91	40	73

'EEF1D MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S819. Gene #85: 'EEF1D MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
EEF1D MUTATED	1	1	1	0
EEF1D WILD-TYPE	135	106	182	83

'EEF1D MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.793 (Fisher's exact test), Q value = 1

Table S820. Gene #85: 'EEF1D MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
EEF1D MUTATED	1	1	1
EEF1D WILD-TYPE	221	183	102

'EEF1D MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.413 (Fisher's exact test), Q value = 1

Table S821. Gene #85: 'EEF1D MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
EEF1D MUTATED	1	0	2
EEF1D WILD-TYPE	183	162	157

'EEF1D MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.587 (Fisher's exact test), Q value = 1

Table S822. Gene #85: 'EEF1D MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
EEF1D MUTATED	1	0	2	0
EEF1D WILD-TYPE	89	138	186	89

'MET MUTATION STATUS' versus 'CN_CNMF'

P value = 0.699 (Fisher's exact test), Q value = 1

Table S823. Gene #86: 'MET MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	169	120	221
MET MUTATED	3	2	2
MET WILD-TYPE	166	118	219

'MET MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.826 (Fisher's exact test), Q value = 1

Table S824. Gene #86: 'MET MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	222	81	168	42
MET MUTATED	3	2	2	0
MET WILD-TYPE	219	79	166	42

'MET MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.785 (Fisher's exact test), Q value = 1

Table S825. Gene #86: 'MET MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	52	62	68	74
MET MUTATED	1	0	1	2
MET WILD-TYPE	51	62	67	72

'MET MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S826. Gene #86: 'MET MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	67	131	58
MET MUTATED	1	2	1
MET WILD-TYPE	66	129	57

'MET MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.922 (Fisher's exact test), Q value = 1

Table S827. Gene #86: 'MET MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	132	109	109	133	30
MET MUTATED	2	2	2	1	0
MET WILD-TYPE	130	107	107	132	30

'MET MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.922 (Fisher's exact test), Q value = 1

Table S828. Gene #86: 'MET MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	134	71	36	66	91	41	74
MET MUTATED	2	1	0	1	2	1	0
MET WILD-TYPE	132	70	36	65	89	40	74

'MET MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S829. Gene #86: 'MET MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
MET MUTATED	2	1	2	1
MET WILD-TYPE	134	106	181	82

'MET MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.509 (Fisher's exact test), Q value = 1

Table S830. Gene #86: 'MET MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
MET MUTATED	3	1	2
MET WILD-TYPE	219	183	101

'MET MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.783 (Fisher's exact test), Q value = 1

Table S831. Gene #86: 'MET MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
MET MUTATED	3	1	2
MET WILD-TYPE	181	161	157

'MET MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.94 (Fisher's exact test), Q value = 1

Table S832. Gene #86: 'MET MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
MET MUTATED	1	1	3	1
MET WILD-TYPE	89	137	185	88

'CUL4B MUTATION STATUS' versus 'CN_CNMF'

P value = 0.294 (Fisher's exact test), Q value = 0.92

Table S833. Gene #87: 'CUL4B MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	169	120	221
CUL4B MUTATED	1	3	6
CUL4B WILD-TYPE	168	117	215

'CUL4B MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0467 (Fisher's exact test), Q value = 0.39

Table S834. Gene #87: 'CUL4B MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	222	81	168	42
CUL4B MUTATED	2	5	3	0
CUL4B WILD-TYPE	220	76	165	42

Figure S178. Get High-res Image Gene #87: 'CUL4B MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

'CUL4B MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.237 (Fisher's exact test), Q value = 0.87

Table S835. Gene #87: 'CUL4B MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	52	62	68	74
CUL4B MUTATED	1	0	2	0
CUL4B WILD-TYPE	51	62	66	74

'CUL4B MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S836. Gene #87: 'CUL4B MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	67	131	58
CUL4B MUTATED	1	2	0
CUL4B WILD-TYPE	66	129	58

'CUL4B MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.091 (Fisher's exact test), Q value = 0.56

Table S837. Gene #87: 'CUL4B MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	132	109	109	133	30
CUL4B MUTATED	1	6	2	1	0
CUL4B WILD-TYPE	131	103	107	132	30

'CUL4B MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0713 (Fisher's exact test), Q value = 0.49

Table S838. Gene #87: 'CUL4B MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	134	71	36	66	91	41	74
CUL4B MUTATED	1	3	1	0	1	3	1
CUL4B WILD-TYPE	133	68	35	66	90	38	73

'CUL4B MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.186 (Fisher's exact test), Q value = 0.81

Table S839. Gene #87: 'CUL4B MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
CUL4B MUTATED	1	5	3	1
CUL4B WILD-TYPE	135	102	180	82

'CUL4B MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0071 (Fisher's exact test), Q value = 0.1

Table S840. Gene #87: 'CUL4B MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
CUL4B MUTATED	1	3	6
CUL4B WILD-TYPE	221	181	97

Figure S179. Get High-res Image Gene #87: 'CUL4B MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

'CUL4B MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S841. Gene #87: 'CUL4B MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
CUL4B MUTATED	4	3	3
CUL4B WILD-TYPE	180	159	156

'CUL4B MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.379 (Fisher's exact test), Q value = 1

Table S842. Gene #87: 'CUL4B MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
CUL4B MUTATED	1	2	3	4
CUL4B WILD-TYPE	89	136	185	85

'SNX31 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.219 (Fisher's exact test), Q value = 0.86

Table S843. Gene #88: 'SNX31 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	169	120	221
SNX31 MUTATED	0	2	2
SNX31 WILD-TYPE	169	118	219

'SNX31 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.306 (Fisher's exact test), Q value = 0.93

Table S844. Gene #88: 'SNX31 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	222	81	168	42
SNX31 MUTATED	1	2	1	0
SNX31 WILD-TYPE	221	79	167	42

'SNX31 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.715 (Fisher's exact test), Q value = 1

Table S845. Gene #88: 'SNX31 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	132	109	109	133	30
SNX31 MUTATED	1	2	0	1	0
SNX31 WILD-TYPE	131	107	109	132	30

'SNX31 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.734 (Fisher's exact test), Q value = 1

Table S846. Gene #88: 'SNX31 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	134	71	36	66	91	41	74
SNX31 MUTATED	1	1	0	0	1	1	0
SNX31 WILD-TYPE	133	70	36	66	90	40	74

'SNX31 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.591 (Fisher's exact test), Q value = 1

Table S847. Gene #88: 'SNX31 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
SNX31 MUTATED	1	2	1	0
SNX31 WILD-TYPE	135	105	182	83

'SNX31 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.342 (Fisher's exact test), Q value = 0.95

Table S848. Gene #88: 'SNX31 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
SNX31 MUTATED	1	1	2
SNX31 WILD-TYPE	221	183	101

'SNX31 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.413 (Fisher's exact test), Q value = 1

Table S849. Gene #88: 'SNX31 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
SNX31 MUTATED	1	0	2
SNX31 WILD-TYPE	183	162	157

'SNX31 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.512 (Fisher's exact test), Q value = 1

Table S850. Gene #88: 'SNX31 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
SNX31 MUTATED	0	0	2	1
SNX31 WILD-TYPE	90	138	186	88

'PHF3 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.018 (Fisher's exact test), Q value = 0.21

Table S851. Gene #89: 'PHF3 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	169	120	221
PHF3 MUTATED	0	5	3
PHF3 WILD-TYPE	169	115	218

Figure S180. Get High-res Image Gene #89: 'PHF3 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

'PHF3 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.694 (Fisher's exact test), Q value = 1

Table S852. Gene #89: 'PHF3 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	222	81	168	42
PHF3 MUTATED	3	2	2	1
PHF3 WILD-TYPE	219	79	166	41

'PHF3 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.706 (Fisher's exact test), Q value = 1

Table S853. Gene #89: 'PHF3 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	52	62	68	74
PHF3 MUTATED	1	1	1	0
PHF3 WILD-TYPE	51	61	67	74

'PHF3 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.794 (Fisher's exact test), Q value = 1

Table S854. Gene #89: 'PHF3 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	67	131	58
PHF3 MUTATED	1	1	1
PHF3 WILD-TYPE	66	130	57

'PHF3 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.261 (Fisher's exact test), Q value = 0.89

Table S855. Gene #89: 'PHF3 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	132	109	109	133	30
PHF3 MUTATED	2	3	2	0	1
PHF3 WILD-TYPE	130	106	107	133	29

'PHF3 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.588 (Fisher's exact test), Q value = 1

Table S856. Gene #89: 'PHF3 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	134	71	36	66	91	41	74
PHF3 MUTATED	2	1	0	1	2	2	0
PHF3 WILD-TYPE	132	70	36	65	89	39	74

'PHF3 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.0954 (Fisher's exact test), Q value = 0.57

Table S857. Gene #89: 'PHF3 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
PHF3 MUTATED	5	2	1	0
PHF3 WILD-TYPE	131	105	182	83

'PHF3 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.262 (Fisher's exact test), Q value = 0.89

Table S858. Gene #89: 'PHF3 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
PHF3 MUTATED	4	1	3
PHF3 WILD-TYPE	218	183	100

'PHF3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.514 (Fisher's exact test), Q value = 1

Table S859. Gene #89: 'PHF3 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
PHF3 MUTATED	4	1	2
PHF3 WILD-TYPE	180	161	157

'PHF3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.874 (Fisher's exact test), Q value = 1

Table S860. Gene #89: 'PHF3 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
PHF3 MUTATED	1	2	2	2
PHF3 WILD-TYPE	89	136	186	87

'G6PC MUTATION STATUS' versus 'CN_CNMF'

P value = 0.329 (Fisher's exact test), Q value = 0.95

Table S861. Gene #90: 'G6PC MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	169	120	221
G6PC MUTATED	1	3	2
G6PC WILD-TYPE	168	117	219

'G6PC MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.146 (Fisher's exact test), Q value = 0.74

Table S862. Gene #90: 'G6PC MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	222	81	168	42
G6PC MUTATED	1	3	2	0
G6PC WILD-TYPE	221	78	166	42

'G6PC MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.842 (Fisher's exact test), Q value = 1

Table S863. Gene #90: 'G6PC MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	52	62	68	74
G6PC MUTATED	0	1	2	1
G6PC WILD-TYPE	52	61	66	73

'G6PC MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.667 (Fisher's exact test), Q value = 1

Table S864. Gene #90: 'G6PC MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	67	131	58
G6PC MUTATED	0	3	1
G6PC WILD-TYPE	67	128	57

'G6PC MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.611 (Fisher's exact test), Q value = 1

Table S865. Gene #90: 'G6PC MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	132	109	109	133	30
G6PC MUTATED	1	1	2	1	1
G6PC WILD-TYPE	131	108	107	132	29

'G6PC MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0803 (Fisher's exact test), Q value = 0.51

Table S866. Gene #90: 'G6PC MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	134	71	36	66	91	41	74
G6PC MUTATED	0	1	1	1	1	2	0
G6PC WILD-TYPE	134	70	35	65	90	39	74

'G6PC MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.429 (Fisher's exact test), Q value = 1

Table S867. Gene #90: 'G6PC MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
G6PC MUTATED	0	2	3	1
G6PC WILD-TYPE	136	105	180	82

'G6PC MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.151 (Fisher's exact test), Q value = 0.76

Table S868. Gene #90: 'G6PC MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
G6PC MUTATED	1	2	3
G6PC WILD-TYPE	221	182	100

'G6PC MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.293 (Fisher's exact test), Q value = 0.92

Table S869. Gene #90: 'G6PC MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
G6PC MUTATED	1	1	4
G6PC WILD-TYPE	183	161	155

'G6PC MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.765 (Fisher's exact test), Q value = 1

Table S870. Gene #90: 'G6PC MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
G6PC MUTATED	1	1	2	2
G6PC WILD-TYPE	89	137	186	87

'FOXQ1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.16 (Fisher's exact test), Q value = 0.78

Table S871. Gene #91: 'FOXQ1 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	169	120	221
FOXQ1 MUTATED	2	2	0
FOXQ1 WILD-TYPE	167	118	221

'FOXQ1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.226 (Fisher's exact test), Q value = 0.86

Table S872. Gene #91: 'FOXQ1 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	222	81	168	42
FOXQ1 MUTATED	2	1	0	1
FOXQ1 WILD-TYPE	220	80	168	41

'FOXQ1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.627 (Fisher's exact test), Q value = 1

Table S873. Gene #91: 'FOXQ1 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	52	62	68	74
FOXQ1 MUTATED	0	0	1	2
FOXQ1 WILD-TYPE	52	62	67	72

'FOXQ1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.192 (Fisher's exact test), Q value = 0.83

Table S874. Gene #91: 'FOXQ1 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	67	131	58
FOXQ1 MUTATED	0	1	2
FOXQ1 WILD-TYPE	67	130	56

'FOXQ1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.927 (Fisher's exact test), Q value = 1

Table S875. Gene #91: 'FOXQ1 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	132	109	109	133	30
FOXQ1 MUTATED	1	1	0	2	0
FOXQ1 WILD-TYPE	131	108	109	131	30

'FOXQ1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.583 (Fisher's exact test), Q value = 1

Table S876. Gene #91: 'FOXQ1 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	134	71	36	66	91	41	74
FOXQ1 MUTATED	1	0	0	1	0	1	1
FOXQ1 WILD-TYPE	133	71	36	65	91	40	73

'FOXQ1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.401 (Fisher's exact test), Q value = 1

Table S877. Gene #91: 'FOXQ1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
FOXQ1 MUTATED	0	2	2	0
FOXQ1 WILD-TYPE	136	105	181	83

'FOXQ1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.682 (Fisher's exact test), Q value = 1

Table S878. Gene #91: 'FOXQ1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
FOXQ1 MUTATED	1	2	1
FOXQ1 WILD-TYPE	221	182	102

'FOXQ1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.0771 (Fisher's exact test), Q value = 0.51

Table S879. Gene #91: 'FOXQ1 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
FOXQ1 MUTATED	0	1	3
FOXQ1 WILD-TYPE	184	161	156

'FOXQ1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.396 (Fisher's exact test), Q value = 1

Table S880. Gene #91: 'FOXQ1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
FOXQ1 MUTATED	1	0	3	0
FOXQ1 WILD-TYPE	89	138	185	89

'AEBP1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.361 (Fisher's exact test), Q value = 0.98

Table S881. Gene #92: 'AEBP1 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	169	120	221
AEBP1 MUTATED	0	1	3
AEBP1 WILD-TYPE	169	119	218

'AEBP1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.398 (Fisher's exact test), Q value = 1

Table S882. Gene #92: 'AEBP1 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	222	81	168	42
AEBP1 MUTATED	1	0	2	1
AEBP1 WILD-TYPE	221	81	166	41

'AEBP1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.234 (Fisher's exact test), Q value = 0.87

Table S883. Gene #92: 'AEBP1 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	52	62	68	74
AEBP1 MUTATED	0	1	0	3
AEBP1 WILD-TYPE	52	61	68	71

'AEBP1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.345 (Fisher's exact test), Q value = 0.95

Table S884. Gene #92: 'AEBP1 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	67	131	58
AEBP1 MUTATED	1	1	2
AEBP1 WILD-TYPE	66	130	56

'AEBP1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.279 (Fisher's exact test), Q value = 0.9

Table S885. Gene #92: 'AEBP1 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	132	109	109	133	30
AEBP1 MUTATED	0	1	0	3	0
AEBP1 WILD-TYPE	132	108	109	130	30

'AEBP1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0189 (Fisher's exact test), Q value = 0.21

Table S886. Gene #92: 'AEBP1 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	134	71	36	66	91	41	74
AEBP1 MUTATED	0	0	0	0	0	1	3
AEBP1 WILD-TYPE	134	71	36	66	91	40	71

Figure S181. Get High-res Image Gene #92: 'AEBP1 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'AEBP1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.486 (Fisher's exact test), Q value = 1

Table S887. Gene #92: 'AEBP1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
AEBP1 MUTATED	1	0	3	0
AEBP1 WILD-TYPE	135	107	180	83

'AEBP1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.422 (Fisher's exact test), Q value = 1

Table S888. Gene #92: 'AEBP1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
AEBP1 MUTATED	1	3	0
AEBP1 WILD-TYPE	221	181	103

'AEBP1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.0771 (Fisher's exact test), Q value = 0.51

Table S889. Gene #92: 'AEBP1 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
AEBP1 MUTATED	0	1	3
AEBP1 WILD-TYPE	184	161	156

'AEBP1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.391 (Fisher's exact test), Q value = 1

Table S890. Gene #92: 'AEBP1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
AEBP1 MUTATED	1	0	3	0
AEBP1 WILD-TYPE	89	138	185	89

'SETD2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0399 (Fisher's exact test), Q value = 0.35

Table S891. Gene #93: 'SETD2 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	169	120	221
SETD2 MUTATED	2	6	2
SETD2 WILD-TYPE	167	114	219

Figure S182. Get High-res Image Gene #93: 'SETD2 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

'SETD2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0631 (Fisher's exact test), Q value = 0.46

Table S892. Gene #93: 'SETD2 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	222	81	168	42
SETD2 MUTATED	3	5	2	0
SETD2 WILD-TYPE	219	76	166	42

'SETD2 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.933 (Fisher's exact test), Q value = 1

Table S893. Gene #93: 'SETD2 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	52	62	68	74
SETD2 MUTATED	1	1	2	1
SETD2 WILD-TYPE	51	61	66	73

'SETD2 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S894. Gene #93: 'SETD2 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	67	131	58
SETD2 MUTATED	1	3	1
SETD2 WILD-TYPE	66	128	57

'SETD2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.00035 (Fisher's exact test), Q value = 0.0086

Table S895. Gene #93: 'SETD2 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	132	109	109	133	30
SETD2 MUTATED	0	5	2	0	3
SETD2 WILD-TYPE	132	104	107	133	27

Figure S183. Get High-res Image Gene #93: 'SETD2 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

'SETD2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.053 (Fisher's exact test), Q value = 0.42

Table S896. Gene #93: 'SETD2 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	134	71	36	66	91	41	74
SETD2 MUTATED	1	2	0	1	1	4	1
SETD2 WILD-TYPE	133	69	36	65	90	37	73

'SETD2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.603 (Fisher's exact test), Q value = 1

Table S897. Gene #93: 'SETD2 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
SETD2 MUTATED	2	4	3	1
SETD2 WILD-TYPE	134	103	180	82

'SETD2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0921 (Fisher's exact test), Q value = 0.56

Table S898. Gene #93: 'SETD2 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
SETD2 MUTATED	3	2	5
SETD2 WILD-TYPE	219	182	98

'SETD2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.854 (Fisher's exact test), Q value = 1

Table S899. Gene #93: 'SETD2 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
SETD2 MUTATED	3	3	4
SETD2 WILD-TYPE	181	159	155

'SETD2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.379 (Fisher's exact test), Q value = 1

Table S900. Gene #93: 'SETD2 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
SETD2 MUTATED	1	2	3	4
SETD2 WILD-TYPE	89	136	185	85

'DST MUTATION STATUS' versus 'CN_CNMF'

P value = 0.235 (Fisher's exact test), Q value = 0.87

Table S901. Gene #94: 'DST MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	169	120	221
DST MUTATED	1	3	7
DST WILD-TYPE	168	117	214

'DST MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.579 (Fisher's exact test), Q value = 1

Table S902. Gene #94: 'DST MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	222	81	168	42
DST MUTATED	4	2	6	0
DST WILD-TYPE	218	79	162	42

'DST MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.497 (Fisher's exact test), Q value = 1

Table S903. Gene #94: 'DST MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	52	62	68	74
DST MUTATED	1	0	3	2
DST WILD-TYPE	51	62	65	72

'DST MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S904. Gene #94: 'DST MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	67	131	58
DST MUTATED	2	3	1
DST WILD-TYPE	65	128	57

'DST MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.85 (Fisher's exact test), Q value = 1

Table S905. Gene #94: 'DST MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	132	109	109	133	30
DST MUTATED	2	2	3	4	1
DST WILD-TYPE	130	107	106	129	29

'DST MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.961 (Fisher's exact test), Q value = 1

Table S906. Gene #94: 'DST MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	134	71	36	66	91	41	74
DST MUTATED	3	1	1	1	2	1	3
DST WILD-TYPE	131	70	35	65	89	40	71

'DST MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.418 (Fisher's exact test), Q value = 1

Table S907. Gene #94: 'DST MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
DST MUTATED	2	5	4	1
DST WILD-TYPE	134	102	179	82

'DST MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.932 (Fisher's exact test), Q value = 1

Table S908. Gene #94: 'DST MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
DST MUTATED	5	5	2
DST WILD-TYPE	217	179	101

'DST MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.406 (Fisher's exact test), Q value = 1

Table S909. Gene #94: 'DST MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
DST MUTATED	3	3	6
DST WILD-TYPE	181	159	153

'DST MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.27 (Fisher's exact test), Q value = 0.9

Table S910. Gene #94: 'DST MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
DST MUTATED	3	1	7	1
DST WILD-TYPE	87	137	181	88

'USP6 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.33 (Fisher's exact test), Q value = 0.95

Table S911. Gene #95: 'USP6 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	169	120	221
USP6 MUTATED	1	3	2
USP6 WILD-TYPE	168	117	219

'USP6 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.507 (Fisher's exact test), Q value = 1

Table S912. Gene #95: 'USP6 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	222	81	168	42
USP6 MUTATED	3	2	1	0
USP6 WILD-TYPE	219	79	167	42

'USP6 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.888 (Fisher's exact test), Q value = 1

Table S913. Gene #95: 'USP6 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	52	62	68	74
USP6 MUTATED	1	0	1	1
USP6 WILD-TYPE	51	62	67	73

'USP6 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.792 (Fisher's exact test), Q value = 1

Table S914. Gene #95: 'USP6 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	67	131	58
USP6 MUTATED	1	1	1
USP6 WILD-TYPE	66	130	57

'USP6 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.447 (Fisher's exact test), Q value = 1

Table S915. Gene #95: 'USP6 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	132	109	109	133	30
USP6 MUTATED	2	3	0	1	0
USP6 WILD-TYPE	130	106	109	132	30

'USP6 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.138 (Fisher's exact test), Q value = 0.72

Table S916. Gene #95: 'USP6 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	134	71	36	66	91	41	74
USP6 MUTATED	1	1	1	1	0	2	0
USP6 WILD-TYPE	133	70	35	65	91	39	74

'USP6 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.728 (Fisher's exact test), Q value = 1

Table S917. Gene #95: 'USP6 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
USP6 MUTATED	2	2	1	1
USP6 WILD-TYPE	134	105	182	82

'USP6 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.218 (Fisher's exact test), Q value = 0.86

Table S918. Gene #95: 'USP6 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
USP6 MUTATED	2	1	3
USP6 WILD-TYPE	220	183	100

'USP6 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S919. Gene #95: 'USP6 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
USP6 MUTATED	2	2	2
USP6 WILD-TYPE	182	160	157

'USP6 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.552 (Fisher's exact test), Q value = 1

Table S920. Gene #95: 'USP6 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
USP6 MUTATED	1	2	1	2
USP6 WILD-TYPE	89	136	187	87

'TPM1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.251 (Fisher's exact test), Q value = 0.89

Table S921. Gene #96: 'TPM1 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	169	120	221
TPM1 MUTATED	0	2	3
TPM1 WILD-TYPE	169	118	218

'TPM1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0942 (Fisher's exact test), Q value = 0.57

Table S922. Gene #96: 'TPM1 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	222	81	168	42
TPM1 MUTATED	0	1	3	1
TPM1 WILD-TYPE	222	80	165	41

'TPM1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.415 (Fisher's exact test), Q value = 1

Table S923. Gene #96: 'TPM1 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	52	62	68	74
TPM1 MUTATED	0	0	2	2
TPM1 WILD-TYPE	52	62	66	72

'TPM1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.263 (Fisher's exact test), Q value = 0.89

Table S924. Gene #96: 'TPM1 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	67	131	58
TPM1 MUTATED	0	2	2
TPM1 WILD-TYPE	67	129	56

'TPM1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.472 (Fisher's exact test), Q value = 1

Table S925. Gene #96: 'TPM1 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	132	109	109	133	30
TPM1 MUTATED	0	1	1	3	0
TPM1 WILD-TYPE	132	108	108	130	30

'TPM1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.039 (Fisher's exact test), Q value = 0.35

Table S926. Gene #96: 'TPM1 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	134	71	36	66	91	41	74
TPM1 MUTATED	0	0	0	1	0	1	3
TPM1 WILD-TYPE	134	71	36	65	91	40	71

Figure S184. Get High-res Image Gene #96: 'TPM1 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'TPM1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.224 (Fisher's exact test), Q value = 0.86

Table S927. Gene #96: 'TPM1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
TPM1 MUTATED	0	1	4	0
TPM1 WILD-TYPE	136	106	179	83

'TPM1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0713 (Fisher's exact test), Q value = 0.49

Table S928. Gene #96: 'TPM1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
TPM1 MUTATED	0	4	1
TPM1 WILD-TYPE	222	180	102

'TPM1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.00303 (Fisher's exact test), Q value = 0.053

Table S929. Gene #96: 'TPM1 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
TPM1 MUTATED	0	0	5
TPM1 WILD-TYPE	184	162	154

Figure S185. Get High-res Image Gene #96: 'TPM1 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

'TPM1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.061 (Fisher's exact test), Q value = 0.45

Table S930. Gene #96: 'TPM1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
TPM1 MUTATED	0	0	5	0
TPM1 WILD-TYPE	90	138	183	89

'GLYAT MUTATION STATUS' versus 'CN_CNMF'

P value = 0.823 (Fisher's exact test), Q value = 1

Table S931. Gene #97: 'GLYAT MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	169	120	221
GLYAT MUTATED	2	1	1
GLYAT WILD-TYPE	167	119	220

'GLYAT MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.88 (Fisher's exact test), Q value = 1

Table S932. Gene #97: 'GLYAT MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	222	81	168	42
GLYAT MUTATED	2	1	1	0
GLYAT WILD-TYPE	220	80	167	42

'GLYAT MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.639 (Fisher's exact test), Q value = 1

Table S933. Gene #97: 'GLYAT MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	132	109	109	133	30
GLYAT MUTATED	2	1	1	0	0
GLYAT WILD-TYPE	130	108	108	133	30

'GLYAT MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.721 (Fisher's exact test), Q value = 1

Table S934. Gene #97: 'GLYAT MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	134	71	36	66	91	41	74
GLYAT MUTATED	2	0	0	0	1	1	0
GLYAT WILD-TYPE	132	71	36	66	90	40	74

'GLYAT MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.195 (Fisher's exact test), Q value = 0.84

Table S935. Gene #97: 'GLYAT MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
GLYAT MUTATED	1	2	0	1
GLYAT WILD-TYPE	135	105	183	82

'GLYAT MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.265 (Fisher's exact test), Q value = 0.89

Table S936. Gene #97: 'GLYAT MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
GLYAT MUTATED	3	0	1
GLYAT WILD-TYPE	219	184	102

'GLYAT MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.838 (Fisher's exact test), Q value = 1

Table S937. Gene #97: 'GLYAT MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
GLYAT MUTATED	1	2	1
GLYAT WILD-TYPE	183	160	158

'GLYAT MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.698 (Fisher's exact test), Q value = 1

Table S938. Gene #97: 'GLYAT MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
GLYAT MUTATED	1	2	1	0
GLYAT WILD-TYPE	89	136	187	89

'DIAPH1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.458 (Fisher's exact test), Q value = 1

Table S939. Gene #98: 'DIAPH1 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	169	120	221
DIAPH1 MUTATED	1	2	1
DIAPH1 WILD-TYPE	168	118	220

'DIAPH1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.228 (Fisher's exact test), Q value = 0.86

Table S940. Gene #98: 'DIAPH1 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	222	81	168	42
DIAPH1 MUTATED	2	1	0	1
DIAPH1 WILD-TYPE	220	80	168	41

'DIAPH1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S941. Gene #98: 'DIAPH1 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	52	62	68	74
DIAPH1 MUTATED	0	1	1	1
DIAPH1 WILD-TYPE	52	61	67	73

'DIAPH1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.612 (Fisher's exact test), Q value = 1

Table S942. Gene #98: 'DIAPH1 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	67	131	58
DIAPH1 MUTATED	0	2	1
DIAPH1 WILD-TYPE	67	129	57

'DIAPH1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.839 (Fisher's exact test), Q value = 1

Table S943. Gene #98: 'DIAPH1 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	132	109	109	133	30
DIAPH1 MUTATED	2	1	0	1	0
DIAPH1 WILD-TYPE	130	108	109	132	30

'DIAPH1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.111 (Fisher's exact test), Q value = 0.63

Table S944. Gene #98: 'DIAPH1 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	134	71	36	66	91	41	74
DIAPH1 MUTATED	1	0	0	1	0	2	0
DIAPH1 WILD-TYPE	133	71	36	65	91	39	74

'DIAPH1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.0813 (Fisher's exact test), Q value = 0.51

Table S945. Gene #98: 'DIAPH1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
DIAPH1 MUTATED	0	3	1	0
DIAPH1 WILD-TYPE	136	104	182	83

'DIAPH1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S946. Gene #98: 'DIAPH1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
DIAPH1 MUTATED	2	1	1
DIAPH1 WILD-TYPE	220	183	102

'DIAPH1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.475 (Fisher's exact test), Q value = 1

Table S947. Gene #98: 'DIAPH1 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
DIAPH1 MUTATED	2	0	2
DIAPH1 WILD-TYPE	182	162	157

'DIAPH1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S948. Gene #98: 'DIAPH1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
DIAPH1 MUTATED	1	1	2	0
DIAPH1 WILD-TYPE	89	137	186	89

'ZMYM2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.618 (Fisher's exact test), Q value = 1

Table S949. Gene #99: 'ZMYM2 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	169	120	221
ZMYM2 MUTATED	1	2	4
ZMYM2 WILD-TYPE	168	118	217

'ZMYM2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.664 (Fisher's exact test), Q value = 1

Table S950. Gene #99: 'ZMYM2 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	222	81	168	42
ZMYM2 MUTATED	2	2	3	0
ZMYM2 WILD-TYPE	220	79	165	42

'ZMYM2 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.525 (Fisher's exact test), Q value = 1

Table S951. Gene #99: 'ZMYM2 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	52	62	68	74
ZMYM2 MUTATED	0	1	3	1
ZMYM2 WILD-TYPE	52	61	65	73

'ZMYM2 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.427 (Fisher's exact test), Q value = 1

Table S952. Gene #99: 'ZMYM2 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	67	131	58
ZMYM2 MUTATED	0	4	1
ZMYM2 WILD-TYPE	67	127	57

'ZMYM2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.627 (Fisher's exact test), Q value = 1

Table S953. Gene #99: 'ZMYM2 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	132	109	109	133	30
ZMYM2 MUTATED	2	2	0	3	0
ZMYM2 WILD-TYPE	130	107	109	130	30

'ZMYM2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.321 (Fisher's exact test), Q value = 0.95

Table S954. Gene #99: 'ZMYM2 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	134	71	36	66	91	41	74
ZMYM2 MUTATED	2	1	0	0	0	1	3
ZMYM2 WILD-TYPE	132	70	36	66	91	40	71

'ZMYM2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.122 (Fisher's exact test), Q value = 0.66

Table S955. Gene #99: 'ZMYM2 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
ZMYM2 MUTATED	0	3	4	0
ZMYM2 WILD-TYPE	136	104	179	83

'ZMYM2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.211 (Fisher's exact test), Q value = 0.85

Table S956. Gene #99: 'ZMYM2 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
ZMYM2 MUTATED	1	4	2
ZMYM2 WILD-TYPE	221	180	101

'ZMYM2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.272 (Fisher's exact test), Q value = 0.9

Table S957. Gene #99: 'ZMYM2 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
ZMYM2 MUTATED	1	2	4
ZMYM2 WILD-TYPE	183	160	155

'ZMYM2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.367 (Fisher's exact test), Q value = 0.99

Table S958. Gene #99: 'ZMYM2 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
ZMYM2 MUTATED	0	1	5	1
ZMYM2 WILD-TYPE	90	137	183	88

'HCFC1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.702 (Fisher's exact test), Q value = 1

Table S959. Gene #100: 'HCFC1 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	169	120	221
HCFC1 MUTATED	3	2	2
HCFC1 WILD-TYPE	166	118	219

'HCFC1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.378 (Fisher's exact test), Q value = 1

Table S960. Gene #100: 'HCFC1 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	222	81	168	42
HCFC1 MUTATED	3	2	1	1
HCFC1 WILD-TYPE	219	79	167	41

'HCFC1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S961. Gene #100: 'HCFC1 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	52	62	68	74
HCFC1 MUTATED	0	1	1	1
HCFC1 WILD-TYPE	52	61	67	73

'HCFC1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.608 (Fisher's exact test), Q value = 1

Table S962. Gene #100: 'HCFC1 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	67	131	58
HCFC1 MUTATED	0	2	1
HCFC1 WILD-TYPE	67	129	57

'HCFC1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.245 (Fisher's exact test), Q value = 0.88

Table S963. Gene #100: 'HCFC1 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	132	109	109	133	30
HCFC1 MUTATED	2	3	0	1	1
HCFC1 WILD-TYPE	130	106	109	132	29

'HCFC1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.612 (Fisher's exact test), Q value = 1

Table S964. Gene #100: 'HCFC1 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	134	71	36	66	91	41	74
HCFC1 MUTATED	2	1	0	0	1	2	1
HCFC1 WILD-TYPE	132	70	36	66	90	39	73

'HCFC1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.221 (Fisher's exact test), Q value = 0.86

Table S965. Gene #100: 'HCFC1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
HCFC1 MUTATED	3	3	1	0
HCFC1 WILD-TYPE	133	104	182	83

'HCFC1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.244 (Fisher's exact test), Q value = 0.88

Table S966. Gene #100: 'HCFC1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
HCFC1 MUTATED	3	1	3
HCFC1 WILD-TYPE	219	183	100

'HCFC1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.893 (Fisher's exact test), Q value = 1

Table S967. Gene #100: 'HCFC1 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
HCFC1 MUTATED	2	3	2
HCFC1 WILD-TYPE	182	159	157

'HCFC1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.909 (Fisher's exact test), Q value = 1

Table S968. Gene #100: 'HCFC1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
HCFC1 MUTATED	2	2	2	1
HCFC1 WILD-TYPE	88	136	186	88

'MST1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.22 (Fisher's exact test), Q value = 0.86

Table S969. Gene #101: 'MST1 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	169	120	221
MST1 MUTATED	0	2	2
MST1 WILD-TYPE	169	118	219

'MST1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.303 (Fisher's exact test), Q value = 0.93

Table S970. Gene #101: 'MST1 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	222	81	168	42
MST1 MUTATED	1	2	1	0
MST1 WILD-TYPE	221	79	167	42

'MST1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.545 (Fisher's exact test), Q value = 1

Table S971. Gene #101: 'MST1 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	132	109	109	133	30
MST1 MUTATED	1	2	1	0	0
MST1 WILD-TYPE	131	107	108	133	30

'MST1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.272 (Fisher's exact test), Q value = 0.9

Table S972. Gene #101: 'MST1 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	134	71	36	66	91	41	74
MST1 MUTATED	1	1	1	0	0	1	0
MST1 WILD-TYPE	133	70	35	66	91	40	74

'MST1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.59 (Fisher's exact test), Q value = 1

Table S973. Gene #101: 'MST1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
MST1 MUTATED	1	2	1	0
MST1 WILD-TYPE	135	105	182	83

'MST1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.344 (Fisher's exact test), Q value = 0.95

Table S974. Gene #101: 'MST1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
MST1 MUTATED	1	1	2
MST1 WILD-TYPE	221	183	101

'MST1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.84 (Fisher's exact test), Q value = 1

Table S975. Gene #101: 'MST1 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
MST1 MUTATED	1	2	1
MST1 WILD-TYPE	183	160	158

'MST1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.522 (Fisher's exact test), Q value = 1

Table S976. Gene #101: 'MST1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
MST1 MUTATED	1	0	2	1
MST1 WILD-TYPE	89	138	186	88

'TNFSF14 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.105 (Fisher's exact test), Q value = 0.61

Table S977. Gene #102: 'TNFSF14 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	169	120	221
TNFSF14 MUTATED	0	3	2
TNFSF14 WILD-TYPE	169	117	219

'TNFSF14 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0284 (Fisher's exact test), Q value = 0.28

Table S978. Gene #102: 'TNFSF14 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	222	81	168	42
TNFSF14 MUTATED	0	3	2	0
TNFSF14 WILD-TYPE	222	78	166	42

Figure S186. Get High-res Image Gene #102: 'TNFSF14 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

'TNFSF14 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0883 (Fisher's exact test), Q value = 0.54

Table S979. Gene #102: 'TNFSF14 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	132	109	109	133	30
TNFSF14 MUTATED	0	3	2	0	0
TNFSF14 WILD-TYPE	132	106	107	133	30

'TNFSF14 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0442 (Fisher's exact test), Q value = 0.37

Table S980. Gene #102: 'TNFSF14 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	134	71	36	66	91	41	74
TNFSF14 MUTATED	0	3	1	0	1	0	0
TNFSF14 WILD-TYPE	134	68	35	66	90	41	74

Figure S187. Get High-res Image Gene #102: 'TNFSF14 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'TNFSF14 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.766 (Fisher's exact test), Q value = 1

Table S981. Gene #102: 'TNFSF14 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
TNFSF14 MUTATED	1	2	2	0
TNFSF14 WILD-TYPE	135	105	181	83

'TNFSF14 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.358 (Fisher's exact test), Q value = 0.98

Table S982. Gene #102: 'TNFSF14 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
TNFSF14 MUTATED	1	2	2
TNFSF14 WILD-TYPE	221	182	101

'TNFSF14 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.332 (Fisher's exact test), Q value = 0.95

Table S983. Gene #102: 'TNFSF14 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
TNFSF14 MUTATED	3	0	2
TNFSF14 WILD-TYPE	181	162	157

'TNFSF14 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.0697 (Fisher's exact test), Q value = 0.49

Table S984. Gene #102: 'TNFSF14 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
TNFSF14 MUTATED	1	0	1	3
TNFSF14 WILD-TYPE	89	138	187	86

'DNAH7 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.846 (Fisher's exact test), Q value = 1

Table S985. Gene #103: 'DNAH7 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	169	120	221
DNAH7 MUTATED	3	3	4
DNAH7 WILD-TYPE	166	117	217

'DNAH7 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.644 (Fisher's exact test), Q value = 1

Table S986. Gene #103: 'DNAH7 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	222	81	168	42
DNAH7 MUTATED	4	3	3	0
DNAH7 WILD-TYPE	218	78	165	42

'DNAH7 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.257 (Fisher's exact test), Q value = 0.89

Table S987. Gene #103: 'DNAH7 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	52	62	68	74
DNAH7 MUTATED	0	2	2	0
DNAH7 WILD-TYPE	52	60	66	74

'DNAH7 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.181 (Fisher's exact test), Q value = 0.81

Table S988. Gene #103: 'DNAH7 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	67	131	58
DNAH7 MUTATED	0	4	0
DNAH7 WILD-TYPE	67	127	58

'DNAH7 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.498 (Fisher's exact test), Q value = 1

Table S989. Gene #103: 'DNAH7 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	132	109	109	133	30
DNAH7 MUTATED	2	4	1	2	1
DNAH7 WILD-TYPE	130	105	108	131	29

'DNAH7 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.342 (Fisher's exact test), Q value = 0.95

Table S990. Gene #103: 'DNAH7 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	134	71	36	66	91	41	74
DNAH7 MUTATED	3	2	0	0	3	2	0
DNAH7 WILD-TYPE	131	69	36	66	88	39	74

'DNAH7 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.639 (Fisher's exact test), Q value = 1

Table S991. Gene #103: 'DNAH7 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
DNAH7 MUTATED	2	3	2	2
DNAH7 WILD-TYPE	134	104	181	81

'DNAH7 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.615 (Fisher's exact test), Q value = 1

Table S992. Gene #103: 'DNAH7 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
DNAH7 MUTATED	3	3	3
DNAH7 WILD-TYPE	219	181	100

'DNAH7 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.592 (Fisher's exact test), Q value = 1

Table S993. Gene #103: 'DNAH7 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
DNAH7 MUTATED	2	3	4
DNAH7 WILD-TYPE	182	159	155

'DNAH7 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.606 (Fisher's exact test), Q value = 1

Table S994. Gene #103: 'DNAH7 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
DNAH7 MUTATED	0	3	4	2
DNAH7 WILD-TYPE	90	135	184	87

'ENGASE MUTATION STATUS' versus 'CN_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S995. Gene #104: 'ENGASE MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	169	120	221
ENGASE MUTATED	2	1	2
ENGASE WILD-TYPE	167	119	219

'ENGASE MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.816 (Fisher's exact test), Q value = 1

Table S996. Gene #104: 'ENGASE MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	222	81	168	42
ENGASE MUTATED	3	1	1	0
ENGASE WILD-TYPE	219	80	167	42

'ENGASE MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.256 (Fisher's exact test), Q value = 0.89

Table S997. Gene #104: 'ENGASE MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	132	109	109	133	30
ENGASE MUTATED	0	2	1	1	1
ENGASE WILD-TYPE	132	107	108	132	29

'ENGASE MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.254 (Fisher's exact test), Q value = 0.89

Table S998. Gene #104: 'ENGASE MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	134	71	36	66	91	41	74
ENGASE MUTATED	1	0	0	1	1	2	0
ENGASE WILD-TYPE	133	71	36	65	90	39	74

'ENGASE MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.673 (Fisher's exact test), Q value = 1

Table S999. Gene #104: 'ENGASE MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
ENGASE MUTATED	1	2	1	1
ENGASE WILD-TYPE	135	105	182	82

'ENGASE MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.528 (Fisher's exact test), Q value = 1

Table S1000. Gene #104: 'ENGASE MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
ENGASE MUTATED	2	1	2
ENGASE WILD-TYPE	220	183	101

'ENGASE MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1001. Gene #104: 'ENGASE MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
ENGASE MUTATED	2	2	1
ENGASE WILD-TYPE	182	160	158

'ENGASE MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S1002. Gene #104: 'ENGASE MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
ENGASE MUTATED	1	1	2	1
ENGASE WILD-TYPE	89	137	186	88

'MYH8 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0796 (Fisher's exact test), Q value = 0.51

Table S1003. Gene #105: 'MYH8 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	169	120	221
MYH8 MUTATED	2	7	5
MYH8 WILD-TYPE	167	113	216

'MYH8 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.184 (Fisher's exact test), Q value = 0.81

Table S1004. Gene #105: 'MYH8 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	222	81	168	42
MYH8 MUTATED	6	5	3	0
MYH8 WILD-TYPE	216	76	165	42

'MYH8 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.597 (Fisher's exact test), Q value = 1

Table S1005. Gene #105: 'MYH8 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	52	62	68	74
MYH8 MUTATED	0	2	3	2
MYH8 WILD-TYPE	52	60	65	72

'MYH8 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.177 (Fisher's exact test), Q value = 0.8

Table S1006. Gene #105: 'MYH8 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	67	131	58
MYH8 MUTATED	0	6	1
MYH8 WILD-TYPE	67	125	57

'MYH8 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.219 (Fisher's exact test), Q value = 0.86

Table S1007. Gene #105: 'MYH8 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	132	109	109	133	30
MYH8 MUTATED	2	6	1	5	0
MYH8 WILD-TYPE	130	103	108	128	30

'MYH8 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0234 (Fisher's exact test), Q value = 0.25

Table S1008. Gene #105: 'MYH8 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	134	71	36	66	91	41	74
MYH8 MUTATED	1	2	1	2	1	5	2
MYH8 WILD-TYPE	133	69	35	64	90	36	72

Figure S188. Get High-res Image Gene #105: 'MYH8 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'MYH8 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.853 (Fisher's exact test), Q value = 1

Table S1009. Gene #105: 'MYH8 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
MYH8 MUTATED	4	4	4	2
MYH8 WILD-TYPE	132	103	179	81

'MYH8 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.255 (Fisher's exact test), Q value = 0.89

Table S1010. Gene #105: 'MYH8 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
MYH8 MUTATED	6	3	5
MYH8 WILD-TYPE	216	181	98

'MYH8 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.838 (Fisher's exact test), Q value = 1

Table S1011. Gene #105: 'MYH8 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
MYH8 MUTATED	4	5	5
MYH8 WILD-TYPE	180	157	154

'MYH8 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.774 (Fisher's exact test), Q value = 1

Table S1012. Gene #105: 'MYH8 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
MYH8 MUTATED	2	3	5	4
MYH8 WILD-TYPE	88	135	183	85

'VSIG4 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.207 (Fisher's exact test), Q value = 0.85

Table S1013. Gene #106: 'VSIG4 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	169	120	221
VSIG4 MUTATED	4	0	2
VSIG4 WILD-TYPE	165	120	219

'VSIG4 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.169 (Fisher's exact test), Q value = 0.79

Table S1014. Gene #106: 'VSIG4 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	222	81	168	42
VSIG4 MUTATED	2	0	2	2
VSIG4 WILD-TYPE	220	81	166	40

'VSIG4 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.451 (Fisher's exact test), Q value = 1

Table S1015. Gene #106: 'VSIG4 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	52	62	68	74
VSIG4 MUTATED	2	0	1	1
VSIG4 WILD-TYPE	50	62	67	73

'VSIG4 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.441 (Fisher's exact test), Q value = 1

Table S1016. Gene #106: 'VSIG4 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	67	131	58
VSIG4 MUTATED	2	1	1
VSIG4 WILD-TYPE	65	130	57

'VSIG4 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.771 (Fisher's exact test), Q value = 1

Table S1017. Gene #106: 'VSIG4 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	132	109	109	133	30
VSIG4 MUTATED	2	0	2	2	0
VSIG4 WILD-TYPE	130	109	107	131	30

'VSIG4 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.501 (Fisher's exact test), Q value = 1

Table S1018. Gene #106: 'VSIG4 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	134	71	36	66	91	41	74
VSIG4 MUTATED	2	0	1	2	1	0	0
VSIG4 WILD-TYPE	132	71	35	64	90	41	74

'VSIG4 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.767 (Fisher's exact test), Q value = 1

Table S1019. Gene #106: 'VSIG4 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
VSIG4 MUTATED	1	1	2	2
VSIG4 WILD-TYPE	135	106	181	81

'VSIG4 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.584 (Fisher's exact test), Q value = 1

Table S1020. Gene #106: 'VSIG4 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
VSIG4 MUTATED	3	3	0
VSIG4 WILD-TYPE	219	181	103

'VSIG4 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.688 (Fisher's exact test), Q value = 1

Table S1021. Gene #106: 'VSIG4 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
VSIG4 MUTATED	2	3	1
VSIG4 WILD-TYPE	182	159	158

'VSIG4 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.394 (Fisher's exact test), Q value = 1

Table S1022. Gene #106: 'VSIG4 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
VSIG4 MUTATED	0	3	3	0
VSIG4 WILD-TYPE	90	135	185	89

'KRT3 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.823 (Fisher's exact test), Q value = 1

Table S1023. Gene #107: 'KRT3 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	169	120	221
KRT3 MUTATED	2	1	1
KRT3 WILD-TYPE	167	119	220

'KRT3 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.879 (Fisher's exact test), Q value = 1

Table S1024. Gene #107: 'KRT3 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	222	81	168	42
KRT3 MUTATED	2	1	1	0
KRT3 WILD-TYPE	220	80	167	42

'KRT3 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.285 (Fisher's exact test), Q value = 0.91

Table S1025. Gene #107: 'KRT3 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	52	62	68	74
KRT3 MUTATED	0	2	1	0
KRT3 WILD-TYPE	52	60	67	74

'KRT3 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.433 (Fisher's exact test), Q value = 1

Table S1026. Gene #107: 'KRT3 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	67	131	58
KRT3 MUTATED	0	3	0
KRT3 WILD-TYPE	67	128	58

'KRT3 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.641 (Fisher's exact test), Q value = 1

Table S1027. Gene #107: 'KRT3 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	132	109	109	133	30
KRT3 MUTATED	2	1	1	0	0
KRT3 WILD-TYPE	130	108	108	133	30

'KRT3 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.734 (Fisher's exact test), Q value = 1

Table S1028. Gene #107: 'KRT3 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	134	71	36	66	91	41	74
KRT3 MUTATED	1	1	0	0	1	1	0
KRT3 WILD-TYPE	133	70	36	66	90	40	74

'KRT3 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.275 (Fisher's exact test), Q value = 0.9

Table S1029. Gene #107: 'KRT3 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
KRT3 MUTATED	2	1	0	1
KRT3 WILD-TYPE	134	106	183	82

'KRT3 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.197 (Fisher's exact test), Q value = 0.84

Table S1030. Gene #107: 'KRT3 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
KRT3 MUTATED	2	0	2
KRT3 WILD-TYPE	220	184	101

'KRT3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.394 (Fisher's exact test), Q value = 1

Table S1031. Gene #107: 'KRT3 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
KRT3 MUTATED	3	1	0
KRT3 WILD-TYPE	181	161	159

'KRT3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.213 (Fisher's exact test), Q value = 0.85

Table S1032. Gene #107: 'KRT3 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
KRT3 MUTATED	2	0	1	1
KRT3 WILD-TYPE	88	138	187	88

'STAG2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0529 (Fisher's exact test), Q value = 0.42

Table S1033. Gene #108: 'STAG2 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	169	120	221
STAG2 MUTATED	0	3	1
STAG2 WILD-TYPE	169	117	220

'STAG2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0294 (Fisher's exact test), Q value = 0.28

Table S1034. Gene #108: 'STAG2 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	222	81	168	42
STAG2 MUTATED	1	3	0	0
STAG2 WILD-TYPE	221	78	168	42

Figure S189. Get High-res Image Gene #108: 'STAG2 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

'STAG2 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1035. Gene #108: 'STAG2 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	52	62	68	74
STAG2 MUTATED	0	1	1	1
STAG2 WILD-TYPE	52	61	67	73

'STAG2 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.609 (Fisher's exact test), Q value = 1

Table S1036. Gene #108: 'STAG2 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	67	131	58
STAG2 MUTATED	0	2	1
STAG2 WILD-TYPE	67	129	57

'STAG2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.143 (Fisher's exact test), Q value = 0.73

Table S1037. Gene #108: 'STAG2 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	132	109	109	133	30
STAG2 MUTATED	0	3	0	1	0
STAG2 WILD-TYPE	132	106	109	132	30

'STAG2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.119 (Fisher's exact test), Q value = 0.65

Table S1038. Gene #108: 'STAG2 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	134	71	36	66	91	41	74
STAG2 MUTATED	0	2	0	0	0	1	1
STAG2 WILD-TYPE	134	69	36	66	91	40	73

'STAG2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.592 (Fisher's exact test), Q value = 1

Table S1039. Gene #108: 'STAG2 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
STAG2 MUTATED	1	2	1	0
STAG2 WILD-TYPE	135	105	182	83

'STAG2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0134 (Fisher's exact test), Q value = 0.17

Table S1040. Gene #108: 'STAG2 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
STAG2 MUTATED	0	1	3
STAG2 WILD-TYPE	222	183	100

Figure S190. Get High-res Image Gene #108: 'STAG2 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

'STAG2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.47 (Fisher's exact test), Q value = 1

Table S1041. Gene #108: 'STAG2 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
STAG2 MUTATED	2	0	2
STAG2 WILD-TYPE	182	162	157

'STAG2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.234 (Fisher's exact test), Q value = 0.87

Table S1042. Gene #108: 'STAG2 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
STAG2 MUTATED	0	0	2	2
STAG2 WILD-TYPE	90	138	186	87

'MUC17 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.65 (Fisher's exact test), Q value = 1

Table S1043. Gene #109: 'MUC17 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	169	120	221
MUC17 MUTATED	9	8	10
MUC17 WILD-TYPE	160	112	211

'MUC17 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.725 (Fisher's exact test), Q value = 1

Table S1044. Gene #109: 'MUC17 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	222	81	168	42
MUC17 MUTATED	12	6	7	2
MUC17 WILD-TYPE	210	75	161	40

'MUC17 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.674 (Fisher's exact test), Q value = 1

Table S1045. Gene #109: 'MUC17 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	52	62	68	74
MUC17 MUTATED	1	4	4	5
MUC17 WILD-TYPE	51	58	64	69

'MUC17 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.586 (Fisher's exact test), Q value = 1

Table S1046. Gene #109: 'MUC17 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	67	131	58
MUC17 MUTATED	2	8	4
MUC17 WILD-TYPE	65	123	54

'MUC17 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.225 (Fisher's exact test), Q value = 0.86

Table S1047. Gene #109: 'MUC17 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	132	109	109	133	30
MUC17 MUTATED	5	9	3	7	3
MUC17 WILD-TYPE	127	100	106	126	27

'MUC17 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.104 (Fisher's exact test), Q value = 0.61

Table S1048. Gene #109: 'MUC17 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	134	71	36	66	91	41	74
MUC17 MUTATED	7	3	4	3	1	5	4
MUC17 WILD-TYPE	127	68	32	63	90	36	70

'MUC17 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.0271 (Fisher's exact test), Q value = 0.27

Table S1049. Gene #109: 'MUC17 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
MUC17 MUTATED	9	4	14	0
MUC17 WILD-TYPE	127	103	169	83

Figure S191. Get High-res Image Gene #109: 'MUC17 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

'MUC17 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0411 (Fisher's exact test), Q value = 0.35

Table S1050. Gene #109: 'MUC17 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
MUC17 MUTATED	6	12	9
MUC17 WILD-TYPE	216	172	94

Figure S192. Get High-res Image Gene #109: 'MUC17 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

'MUC17 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.0264 (Fisher's exact test), Q value = 0.27

Table S1051. Gene #109: 'MUC17 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
MUC17 MUTATED	7	5	15
MUC17 WILD-TYPE	177	157	144

Figure S193. Get High-res Image Gene #109: 'MUC17 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

'MUC17 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.0617 (Fisher's exact test), Q value = 0.45

Table S1052. Gene #109: 'MUC17 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
MUC17 MUTATED	5	2	13	7
MUC17 WILD-TYPE	85	136	175	82

'ABCA7 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.704 (Fisher's exact test), Q value = 1

Table S1053. Gene #110: 'ABCA7 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	169	120	221
ABCA7 MUTATED	3	3	3
ABCA7 WILD-TYPE	166	117	218

'ABCA7 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.382 (Fisher's exact test), Q value = 1

Table S1054. Gene #110: 'ABCA7 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	222	81	168	42
ABCA7 MUTATED	3	3	2	1
ABCA7 WILD-TYPE	219	78	166	41

'ABCA7 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.124 (Fisher's exact test), Q value = 0.66

Table S1055. Gene #110: 'ABCA7 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	52	62	68	74
ABCA7 MUTATED	3	1	1	0
ABCA7 WILD-TYPE	49	61	67	74

'ABCA7 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.226 (Fisher's exact test), Q value = 0.86

Table S1056. Gene #110: 'ABCA7 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	67	131	58
ABCA7 MUTATED	3	2	0
ABCA7 WILD-TYPE	64	129	58

'ABCA7 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.266 (Fisher's exact test), Q value = 0.89

Table S1057. Gene #110: 'ABCA7 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	132	109	109	133	30
ABCA7 MUTATED	1	5	1	2	0
ABCA7 WILD-TYPE	131	104	108	131	30

'ABCA7 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.212 (Fisher's exact test), Q value = 0.85

Table S1058. Gene #110: 'ABCA7 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	134	71	36	66	91	41	74
ABCA7 MUTATED	1	1	0	1	1	3	2
ABCA7 WILD-TYPE	133	70	36	65	90	38	72

'ABCA7 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1059. Gene #110: 'ABCA7 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
ABCA7 MUTATED	2	2	4	1
ABCA7 WILD-TYPE	134	105	179	82

'ABCA7 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0546 (Fisher's exact test), Q value = 0.42

Table S1060. Gene #110: 'ABCA7 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
ABCA7 MUTATED	2	2	5
ABCA7 WILD-TYPE	220	182	98

'ABCA7 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.0978 (Fisher's exact test), Q value = 0.58

Table S1061. Gene #110: 'ABCA7 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
ABCA7 MUTATED	1	2	6
ABCA7 WILD-TYPE	183	160	153

'ABCA7 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.25 (Fisher's exact test), Q value = 0.89

Table S1062. Gene #110: 'ABCA7 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
ABCA7 MUTATED	1	1	3	4
ABCA7 WILD-TYPE	89	137	185	85

'FOXK1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0532 (Fisher's exact test), Q value = 0.42

Table S1063. Gene #111: 'FOXK1 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	169	120	221
FOXK1 MUTATED	0	3	1
FOXK1 WILD-TYPE	169	117	220

'FOXK1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0799 (Fisher's exact test), Q value = 0.51

Table S1064. Gene #111: 'FOXK1 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	222	81	168	42
FOXK1 MUTATED	1	0	1	2
FOXK1 WILD-TYPE	221	81	167	40

'FOXK1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.674 (Fisher's exact test), Q value = 1

Table S1065. Gene #111: 'FOXK1 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	52	62	68	74
FOXK1 MUTATED	1	0	2	1
FOXK1 WILD-TYPE	51	62	66	73

'FOXK1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S1066. Gene #111: 'FOXK1 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	67	131	58
FOXK1 MUTATED	1	2	1
FOXK1 WILD-TYPE	66	129	57

'FOXK1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.928 (Fisher's exact test), Q value = 1

Table S1067. Gene #111: 'FOXK1 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	132	109	109	133	30
FOXK1 MUTATED	1	0	1	2	0
FOXK1 WILD-TYPE	131	109	108	131	30

'FOXK1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.575 (Fisher's exact test), Q value = 1

Table S1068. Gene #111: 'FOXK1 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	134	71	36	66	91	41	74
FOXK1 MUTATED	1	0	0	2	1	0	0
FOXK1 WILD-TYPE	133	71	36	64	90	41	74

'FOXK1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.832 (Fisher's exact test), Q value = 1

Table S1069. Gene #111: 'FOXK1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
FOXK1 MUTATED	1	0	2	1
FOXK1 WILD-TYPE	135	107	181	82

'FOXK1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.833 (Fisher's exact test), Q value = 1

Table S1070. Gene #111: 'FOXK1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
FOXK1 MUTATED	2	2	0
FOXK1 WILD-TYPE	220	182	103

'FOXK1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.838 (Fisher's exact test), Q value = 1

Table S1071. Gene #111: 'FOXK1 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
FOXK1 MUTATED	1	2	1
FOXK1 WILD-TYPE	183	160	158

'FOXK1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.394 (Fisher's exact test), Q value = 1

Table S1072. Gene #111: 'FOXK1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
FOXK1 MUTATED	1	0	3	0
FOXK1 WILD-TYPE	89	138	185	89

'SLFN11 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.824 (Fisher's exact test), Q value = 1

Table S1073. Gene #112: 'SLFN11 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	169	120	221
SLFN11 MUTATED	2	1	1
SLFN11 WILD-TYPE	167	119	220

'SLFN11 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.879 (Fisher's exact test), Q value = 1

Table S1074. Gene #112: 'SLFN11 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	222	81	168	42
SLFN11 MUTATED	2	1	1	0
SLFN11 WILD-TYPE	220	80	167	42

'SLFN11 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.56 (Fisher's exact test), Q value = 1

Table S1075. Gene #112: 'SLFN11 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	52	62	68	74
SLFN11 MUTATED	0	0	2	1
SLFN11 WILD-TYPE	52	62	66	73

'SLFN11 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.797 (Fisher's exact test), Q value = 1

Table S1076. Gene #112: 'SLFN11 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	67	131	58
SLFN11 MUTATED	1	1	1
SLFN11 WILD-TYPE	66	130	57

'SLFN11 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.313 (Fisher's exact test), Q value = 0.94

Table S1077. Gene #112: 'SLFN11 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	132	109	109	133	30
SLFN11 MUTATED	0	1	1	1	1
SLFN11 WILD-TYPE	132	108	108	132	29

'SLFN11 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.714 (Fisher's exact test), Q value = 1

Table S1078. Gene #112: 'SLFN11 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	134	71	36	66	91	41	74
SLFN11 MUTATED	1	0	0	1	1	1	0
SLFN11 WILD-TYPE	133	71	36	65	90	40	74

'SLFN11 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.592 (Fisher's exact test), Q value = 1

Table S1079. Gene #112: 'SLFN11 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
SLFN11 MUTATED	1	2	1	0
SLFN11 WILD-TYPE	135	105	182	83

'SLFN11 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.265 (Fisher's exact test), Q value = 0.89

Table S1080. Gene #112: 'SLFN11 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
SLFN11 MUTATED	3	0	1
SLFN11 WILD-TYPE	219	184	102

'SLFN11 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.473 (Fisher's exact test), Q value = 1

Table S1081. Gene #112: 'SLFN11 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
SLFN11 MUTATED	2	0	2
SLFN11 WILD-TYPE	182	162	157

'SLFN11 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.757 (Fisher's exact test), Q value = 1

Table S1082. Gene #112: 'SLFN11 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
SLFN11 MUTATED	0	2	2	0
SLFN11 WILD-TYPE	90	136	186	89

'MX2 MUTATION STATUS' versus 'CN_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1083. Gene #113: 'MX2 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	169	120	221
MX2 MUTATED	1	1	2
MX2 WILD-TYPE	168	119	219

'MX2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.658 (Fisher's exact test), Q value = 1

Table S1084. Gene #113: 'MX2 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	222	81	168	42
MX2 MUTATED	1	1	2	0
MX2 WILD-TYPE	221	80	166	42

'MX2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1085. Gene #113: 'MX2 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	132	109	109	133	30
MX2 MUTATED	1	1	1	1	0
MX2 WILD-TYPE	131	108	108	132	30

'MX2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.664 (Fisher's exact test), Q value = 1

Table S1086. Gene #113: 'MX2 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	134	71	36	66	91	41	74
MX2 MUTATED	1	1	1	0	1	0	0
MX2 WILD-TYPE	133	70	35	66	90	41	74

'MX2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.368 (Fisher's exact test), Q value = 0.99

Table S1087. Gene #113: 'MX2 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
MX2 MUTATED	0	2	1	1
MX2 WILD-TYPE	136	105	182	82

'MX2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S1088. Gene #113: 'MX2 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
MX2 MUTATED	2	1	1
MX2 WILD-TYPE	220	183	102

'MX2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1089. Gene #113: 'MX2 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
MX2 MUTATED	2	1	1
MX2 WILD-TYPE	182	161	158

'MX2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.639 (Fisher's exact test), Q value = 1

Table S1090. Gene #113: 'MX2 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
MX2 MUTATED	0	2	1	1
MX2 WILD-TYPE	90	136	187	88

'SLC6A4 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.531 (Fisher's exact test), Q value = 1

Table S1091. Gene #114: 'SLC6A4 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	169	120	221
SLC6A4 MUTATED	2	2	1
SLC6A4 WILD-TYPE	167	118	220

'SLC6A4 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.206 (Fisher's exact test), Q value = 0.85

Table S1092. Gene #114: 'SLC6A4 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	222	81	168	42
SLC6A4 MUTATED	3	2	0	0
SLC6A4 WILD-TYPE	219	79	168	42

'SLC6A4 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.0404 (Fisher's exact test), Q value = 0.35

Table S1093. Gene #114: 'SLC6A4 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	52	62	68	74
SLC6A4 MUTATED	0	0	3	0
SLC6A4 WILD-TYPE	52	62	65	74

Figure S194. Get High-res Image Gene #114: 'SLC6A4 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

'SLC6A4 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.429 (Fisher's exact test), Q value = 1

Table S1094. Gene #114: 'SLC6A4 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	67	131	58
SLC6A4 MUTATED	0	3	0
SLC6A4 WILD-TYPE	67	128	58

'SLC6A4 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.724 (Fisher's exact test), Q value = 1

Table S1095. Gene #114: 'SLC6A4 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	132	109	109	133	30
SLC6A4 MUTATED	2	2	0	1	0
SLC6A4 WILD-TYPE	130	107	109	132	30

'SLC6A4 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.163 (Fisher's exact test), Q value = 0.78

Table S1096. Gene #114: 'SLC6A4 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	134	71	36	66	91	41	74
SLC6A4 MUTATED	2	0	0	1	0	2	0
SLC6A4 WILD-TYPE	132	71	36	65	91	39	74

'SLC6A4 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.927 (Fisher's exact test), Q value = 1

Table S1097. Gene #114: 'SLC6A4 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
SLC6A4 MUTATED	2	1	2	0
SLC6A4 WILD-TYPE	134	106	181	83

'SLC6A4 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.848 (Fisher's exact test), Q value = 1

Table S1098. Gene #114: 'SLC6A4 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
SLC6A4 MUTATED	3	1	1
SLC6A4 WILD-TYPE	219	183	102

'SLC6A4 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.871 (Fisher's exact test), Q value = 1

Table S1099. Gene #114: 'SLC6A4 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
SLC6A4 MUTATED	2	1	2
SLC6A4 WILD-TYPE	182	161	157

'SLC6A4 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.212 (Fisher's exact test), Q value = 0.85

Table S1100. Gene #114: 'SLC6A4 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
SLC6A4 MUTATED	2	0	3	0
SLC6A4 WILD-TYPE	88	138	185	89

'KRT15 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.331 (Fisher's exact test), Q value = 0.95

Table S1101. Gene #115: 'KRT15 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	169	120	221
KRT15 MUTATED	1	3	2
KRT15 WILD-TYPE	168	117	219

'KRT15 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1102. Gene #115: 'KRT15 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	222	81	168	42
KRT15 MUTATED	3	1	2	0
KRT15 WILD-TYPE	219	80	166	42

'KRT15 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.487 (Fisher's exact test), Q value = 1

Table S1103. Gene #115: 'KRT15 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	132	109	109	133	30
KRT15 MUTATED	0	2	1	3	0
KRT15 WILD-TYPE	132	107	108	130	30

'KRT15 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.462 (Fisher's exact test), Q value = 1

Table S1104. Gene #115: 'KRT15 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	134	71	36	66	91	41	74
KRT15 MUTATED	0	1	0	1	2	1	1
KRT15 WILD-TYPE	134	70	36	65	89	40	73

'KRT15 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.517 (Fisher's exact test), Q value = 1

Table S1105. Gene #115: 'KRT15 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
KRT15 MUTATED	3	0	2	1
KRT15 WILD-TYPE	133	107	181	82

'KRT15 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.868 (Fisher's exact test), Q value = 1

Table S1106. Gene #115: 'KRT15 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
KRT15 MUTATED	2	3	1
KRT15 WILD-TYPE	220	181	102

'KRT15 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1107. Gene #115: 'KRT15 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
KRT15 MUTATED	2	2	2
KRT15 WILD-TYPE	182	160	157

'KRT15 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S1108. Gene #115: 'KRT15 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
KRT15 MUTATED	1	2	2	1
KRT15 WILD-TYPE	89	136	186	88

'F8 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.00438 (Fisher's exact test), Q value = 0.071

Table S1109. Gene #116: 'F8 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	169	120	221
F8 MUTATED	4	5	0
F8 WILD-TYPE	165	115	221

Figure S195. Get High-res Image Gene #116: 'F8 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

'F8 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.00531 (Fisher's exact test), Q value = 0.08

Table S1110. Gene #116: 'F8 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	222	81	168	42
F8 MUTATED	3	5	0	1
F8 WILD-TYPE	219	76	168	41

Figure S196. Get High-res Image Gene #116: 'F8 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

'F8 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.344 (Fisher's exact test), Q value = 0.95

Table S1111. Gene #116: 'F8 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	52	62	68	74
F8 MUTATED	2	1	1	0
F8 WILD-TYPE	50	61	67	74

'F8 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.81 (Fisher's exact test), Q value = 1

Table S1112. Gene #116: 'F8 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	67	131	58
F8 MUTATED	1	3	0
F8 WILD-TYPE	66	128	58

'F8 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.034 (Fisher's exact test), Q value = 0.31

Table S1113. Gene #116: 'F8 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	132	109	109	133	30
F8 MUTATED	2	6	0	1	0
F8 WILD-TYPE	130	103	109	132	30

Figure S197. Get High-res Image Gene #116: 'F8 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

'F8 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.055 (Fisher's exact test), Q value = 0.42

Table S1114. Gene #116: 'F8 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	134	71	36	66	91	41	74
F8 MUTATED	2	4	0	1	0	2	0
F8 WILD-TYPE	132	67	36	65	91	39	74

'F8 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.174 (Fisher's exact test), Q value = 0.8

Table S1115. Gene #116: 'F8 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
F8 MUTATED	2	4	1	2
F8 WILD-TYPE	134	103	182	81

'F8 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0961 (Fisher's exact test), Q value = 0.57

Table S1116. Gene #116: 'F8 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
F8 MUTATED	4	1	4
F8 WILD-TYPE	218	183	99

'F8 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.342 (Fisher's exact test), Q value = 0.95

Table S1117. Gene #116: 'F8 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
F8 MUTATED	5	1	3
F8 WILD-TYPE	179	161	156

'F8 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.578 (Fisher's exact test), Q value = 1

Table S1118. Gene #116: 'F8 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
F8 MUTATED	1	3	2	3
F8 WILD-TYPE	89	135	186	86

'HOOK1 MUTATION STATUS' versus 'CN_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1119. Gene #117: 'HOOK1 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	169	120	221
HOOK1 MUTATED	1	1	1
HOOK1 WILD-TYPE	168	119	220

'HOOK1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.68 (Fisher's exact test), Q value = 1

Table S1120. Gene #117: 'HOOK1 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	222	81	168	42
HOOK1 MUTATED	1	1	1	0
HOOK1 WILD-TYPE	221	80	167	42

'HOOK1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.277 (Fisher's exact test), Q value = 0.9

Table S1121. Gene #117: 'HOOK1 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	132	109	109	133	30
HOOK1 MUTATED	0	2	1	0	0
HOOK1 WILD-TYPE	132	107	108	133	30

'HOOK1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00351 (Fisher's exact test), Q value = 0.06

Table S1122. Gene #117: 'HOOK1 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	134	71	36	66	91	41	74
HOOK1 MUTATED	0	0	1	0	0	2	0
HOOK1 WILD-TYPE	134	71	35	66	91	39	74

Figure S198. Get High-res Image Gene #117: 'HOOK1 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'HOOK1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.327 (Fisher's exact test), Q value = 0.95

Table S1123. Gene #117: 'HOOK1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
HOOK1 MUTATED	0	2	1	0
HOOK1 WILD-TYPE	136	105	182	83

'HOOK1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.153 (Fisher's exact test), Q value = 0.76

Table S1124. Gene #117: 'HOOK1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
HOOK1 MUTATED	1	0	2
HOOK1 WILD-TYPE	221	184	101

'HOOK1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1125. Gene #117: 'HOOK1 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
HOOK1 MUTATED	1	1	1
HOOK1 WILD-TYPE	183	161	158

'HOOK1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.777 (Fisher's exact test), Q value = 1

Table S1126. Gene #117: 'HOOK1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
HOOK1 MUTATED	0	1	1	1
HOOK1 WILD-TYPE	90	137	187	88

'FMR1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.451 (Fisher's exact test), Q value = 1

Table S1127. Gene #118: 'FMR1 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	169	120	221
FMR1 MUTATED	3	1	1
FMR1 WILD-TYPE	166	119	220

'FMR1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.126 (Fisher's exact test), Q value = 0.67

Table S1128. Gene #118: 'FMR1 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	222	81	168	42
FMR1 MUTATED	2	2	0	1
FMR1 WILD-TYPE	220	79	168	41

'FMR1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.198 (Fisher's exact test), Q value = 0.84

Table S1129. Gene #118: 'FMR1 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	132	109	109	133	30
FMR1 MUTATED	3	2	0	0	0
FMR1 WILD-TYPE	129	107	109	133	30

'FMR1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.453 (Fisher's exact test), Q value = 1

Table S1130. Gene #118: 'FMR1 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	134	71	36	66	91	41	74
FMR1 MUTATED	3	1	0	0	0	1	0
FMR1 WILD-TYPE	131	70	36	66	91	40	74

'FMR1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.241 (Fisher's exact test), Q value = 0.88

Table S1131. Gene #118: 'FMR1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
FMR1 MUTATED	1	3	1	0
FMR1 WILD-TYPE	135	104	182	83

'FMR1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.36 (Fisher's exact test), Q value = 0.98

Table S1132. Gene #118: 'FMR1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
FMR1 MUTATED	1	2	2
FMR1 WILD-TYPE	221	182	101

'FMR1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.334 (Fisher's exact test), Q value = 0.95

Table S1133. Gene #118: 'FMR1 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
FMR1 MUTATED	3	0	2
FMR1 WILD-TYPE	181	162	157

'FMR1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S1134. Gene #118: 'FMR1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
FMR1 MUTATED	1	1	2	1
FMR1 WILD-TYPE	89	137	186	88

'SON MUTATION STATUS' versus 'CN_CNMF'

P value = 0.222 (Fisher's exact test), Q value = 0.86

Table S1135. Gene #119: 'SON MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	169	120	221
SON MUTATED	2	4	2
SON WILD-TYPE	167	116	219

'SON MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.107 (Fisher's exact test), Q value = 0.61

Table S1136. Gene #119: 'SON MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	222	81	168	42
SON MUTATED	2	4	2	0
SON WILD-TYPE	220	77	166	42

'SON MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.495 (Fisher's exact test), Q value = 1

Table S1137. Gene #119: 'SON MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	52	62	68	74
SON MUTATED	1	0	3	2
SON WILD-TYPE	51	62	65	72

'SON MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.218 (Fisher's exact test), Q value = 0.86

Table S1138. Gene #119: 'SON MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	67	131	58
SON MUTATED	0	5	1
SON WILD-TYPE	67	126	57

'SON MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.772 (Fisher's exact test), Q value = 1

Table S1139. Gene #119: 'SON MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	132	109	109	133	30
SON MUTATED	2	3	2	1	0
SON WILD-TYPE	130	106	107	132	30

'SON MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.713 (Fisher's exact test), Q value = 1

Table S1140. Gene #119: 'SON MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	134	71	36	66	91	41	74
SON MUTATED	2	2	1	1	1	1	0
SON WILD-TYPE	132	69	35	65	90	40	74

'SON MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.828 (Fisher's exact test), Q value = 1

Table S1141. Gene #119: 'SON MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
SON MUTATED	2	2	2	2
SON WILD-TYPE	134	105	181	81

'SON MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.52 (Fisher's exact test), Q value = 1

Table S1142. Gene #119: 'SON MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
SON MUTATED	3	2	3
SON WILD-TYPE	219	182	100

'SON MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.642 (Fisher's exact test), Q value = 1

Table S1143. Gene #119: 'SON MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
SON MUTATED	3	1	3
SON WILD-TYPE	181	161	156

'SON MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.158 (Fisher's exact test), Q value = 0.77

Table S1144. Gene #119: 'SON MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
SON MUTATED	1	0	3	3
SON WILD-TYPE	89	138	185	86

'TTC30B MUTATION STATUS' versus 'CN_CNMF'

P value = 0.769 (Fisher's exact test), Q value = 1

Table S1145. Gene #120: 'TTC30B MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	169	120	221
TTC30B MUTATED	3	1	2
TTC30B WILD-TYPE	166	119	219

'TTC30B MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.74 (Fisher's exact test), Q value = 1

Table S1146. Gene #120: 'TTC30B MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	222	81	168	42
TTC30B MUTATED	4	1	1	0
TTC30B WILD-TYPE	218	80	167	42

'TTC30B MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.794 (Fisher's exact test), Q value = 1

Table S1147. Gene #120: 'TTC30B MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	132	109	109	133	30
TTC30B MUTATED	3	1	1	1	0
TTC30B WILD-TYPE	129	108	108	132	30

'TTC30B MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.403 (Fisher's exact test), Q value = 1

Table S1148. Gene #120: 'TTC30B MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	134	71	36	66	91	41	74
TTC30B MUTATED	2	0	0	0	1	2	1
TTC30B WILD-TYPE	132	71	36	66	90	39	73

'TTC30B MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.0757 (Fisher's exact test), Q value = 0.51

Table S1149. Gene #120: 'TTC30B MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
TTC30B MUTATED	1	4	1	0
TTC30B WILD-TYPE	135	103	182	83

'TTC30B MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.667 (Fisher's exact test), Q value = 1

Table S1150. Gene #120: 'TTC30B MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
TTC30B MUTATED	4	1	1
TTC30B WILD-TYPE	218	183	102

'TTC30B MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.454 (Fisher's exact test), Q value = 1

Table S1151. Gene #120: 'TTC30B MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
TTC30B MUTATED	1	2	3
TTC30B WILD-TYPE	183	160	156

'TTC30B MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.392 (Fisher's exact test), Q value = 1

Table S1152. Gene #120: 'TTC30B MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
TTC30B MUTATED	0	3	3	0
TTC30B WILD-TYPE	90	135	185	89

'FANCD2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.55 (Fisher's exact test), Q value = 1

Table S1153. Gene #121: 'FANCD2 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	169	120	221
FANCD2 MUTATED	2	3	2
FANCD2 WILD-TYPE	167	117	219

'FANCD2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.197 (Fisher's exact test), Q value = 0.84

Table S1154. Gene #121: 'FANCD2 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	222	81	168	42
FANCD2 MUTATED	3	1	1	2
FANCD2 WILD-TYPE	219	80	167	40

'FANCD2 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.0399 (Fisher's exact test), Q value = 0.35

Table S1155. Gene #121: 'FANCD2 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	52	62	68	74
FANCD2 MUTATED	0	0	3	0
FANCD2 WILD-TYPE	52	62	65	74

Figure S199. Get High-res Image Gene #121: 'FANCD2 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

'FANCD2 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.429 (Fisher's exact test), Q value = 1

Table S1156. Gene #121: 'FANCD2 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	67	131	58
FANCD2 MUTATED	0	3	0
FANCD2 WILD-TYPE	67	128	58

'FANCD2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.103 (Fisher's exact test), Q value = 0.61

Table S1157. Gene #121: 'FANCD2 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	132	109	109	133	30
FANCD2 MUTATED	1	2	0	2	2
FANCD2 WILD-TYPE	131	107	109	131	28

'FANCD2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.609 (Fisher's exact test), Q value = 1

Table S1158. Gene #121: 'FANCD2 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	134	71	36	66	91	41	74
FANCD2 MUTATED	2	1	0	0	1	2	1
FANCD2 WILD-TYPE	132	70	36	66	90	39	73

'FANCD2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.87 (Fisher's exact test), Q value = 1

Table S1159. Gene #121: 'FANCD2 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
FANCD2 MUTATED	3	1	2	1
FANCD2 WILD-TYPE	133	106	181	82

'FANCD2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.331 (Fisher's exact test), Q value = 0.95

Table S1160. Gene #121: 'FANCD2 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
FANCD2 MUTATED	2	2	3
FANCD2 WILD-TYPE	220	182	100

'FANCD2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.802 (Fisher's exact test), Q value = 1

Table S1161. Gene #121: 'FANCD2 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
FANCD2 MUTATED	2	2	3
FANCD2 WILD-TYPE	182	160	156

'FANCD2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.22 (Fisher's exact test), Q value = 0.86

Table S1162. Gene #121: 'FANCD2 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
FANCD2 MUTATED	2	0	3	2
FANCD2 WILD-TYPE	88	138	185	87

'RGL2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.822 (Fisher's exact test), Q value = 1

Table S1163. Gene #122: 'RGL2 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	169	120	221
RGL2 MUTATED	2	1	1
RGL2 WILD-TYPE	167	119	220

'RGL2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.878 (Fisher's exact test), Q value = 1

Table S1164. Gene #122: 'RGL2 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	222	81	168	42
RGL2 MUTATED	2	1	1	0
RGL2 WILD-TYPE	220	80	167	42

'RGL2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.714 (Fisher's exact test), Q value = 1

Table S1165. Gene #122: 'RGL2 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	132	109	109	133	30
RGL2 MUTATED	1	2	0	1	0
RGL2 WILD-TYPE	131	107	109	132	30

'RGL2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0353 (Fisher's exact test), Q value = 0.32

Table S1166. Gene #122: 'RGL2 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	134	71	36	66	91	41	74
RGL2 MUTATED	1	0	1	0	0	2	0
RGL2 WILD-TYPE	133	71	35	66	91	39	74

Figure S200. Get High-res Image Gene #122: 'RGL2 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'RGL2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.404 (Fisher's exact test), Q value = 1

Table S1167. Gene #122: 'RGL2 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
RGL2 MUTATED	0	2	2	0
RGL2 WILD-TYPE	136	105	181	83

'RGL2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.34 (Fisher's exact test), Q value = 0.95

Table S1168. Gene #122: 'RGL2 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
RGL2 MUTATED	1	1	2
RGL2 WILD-TYPE	221	183	101

'RGL2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.694 (Fisher's exact test), Q value = 1

Table S1169. Gene #122: 'RGL2 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
RGL2 MUTATED	1	1	2
RGL2 WILD-TYPE	183	161	157

'RGL2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.58 (Fisher's exact test), Q value = 1

Table S1170. Gene #122: 'RGL2 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
RGL2 MUTATED	0	1	3	0
RGL2 WILD-TYPE	90	137	185	89

'NR1H3 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.455 (Fisher's exact test), Q value = 1

Table S1171. Gene #123: 'NR1H3 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	169	120	221
NR1H3 MUTATED	1	2	1
NR1H3 WILD-TYPE	168	118	220

'NR1H3 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.302 (Fisher's exact test), Q value = 0.93

Table S1172. Gene #123: 'NR1H3 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	222	81	168	42
NR1H3 MUTATED	1	2	1	0
NR1H3 WILD-TYPE	221	79	167	42

'NR1H3 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.24 (Fisher's exact test), Q value = 0.88

Table S1173. Gene #123: 'NR1H3 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	52	62	68	74
NR1H3 MUTATED	1	0	2	0
NR1H3 WILD-TYPE	51	62	66	74

'NR1H3 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S1174. Gene #123: 'NR1H3 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	67	131	58
NR1H3 MUTATED	1	2	0
NR1H3 WILD-TYPE	66	129	58

'NR1H3 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0719 (Fisher's exact test), Q value = 0.5

Table S1175. Gene #123: 'NR1H3 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	132	109	109	133	30
NR1H3 MUTATED	0	3	1	0	0
NR1H3 WILD-TYPE	132	106	108	133	30

'NR1H3 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0578 (Fisher's exact test), Q value = 0.43

Table S1176. Gene #123: 'NR1H3 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	134	71	36	66	91	41	74
NR1H3 MUTATED	0	1	0	0	1	2	0
NR1H3 WILD-TYPE	134	70	36	66	90	39	74

'NR1H3 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.0801 (Fisher's exact test), Q value = 0.51

Table S1177. Gene #123: 'NR1H3 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
NR1H3 MUTATED	0	3	1	0
NR1H3 WILD-TYPE	136	104	182	83

'NR1H3 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0135 (Fisher's exact test), Q value = 0.17

Table S1178. Gene #123: 'NR1H3 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
NR1H3 MUTATED	0	1	3
NR1H3 WILD-TYPE	222	183	100

Figure S201. Get High-res Image Gene #123: 'NR1H3 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

'NR1H3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.473 (Fisher's exact test), Q value = 1

Table S1179. Gene #123: 'NR1H3 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
NR1H3 MUTATED	2	0	2
NR1H3 WILD-TYPE	182	162	157

'NR1H3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.236 (Fisher's exact test), Q value = 0.87

Table S1180. Gene #123: 'NR1H3 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
NR1H3 MUTATED	0	0	2	2
NR1H3 WILD-TYPE	90	138	186	87

'TYRP1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.456 (Fisher's exact test), Q value = 1

Table S1181. Gene #124: 'TYRP1 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	169	120	221
TYRP1 MUTATED	1	2	1
TYRP1 WILD-TYPE	168	118	220

'TYRP1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.305 (Fisher's exact test), Q value = 0.93

Table S1182. Gene #124: 'TYRP1 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	222	81	168	42
TYRP1 MUTATED	1	2	1	0
TYRP1 WILD-TYPE	221	79	167	42

'TYRP1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.108 (Fisher's exact test), Q value = 0.62

Table S1183. Gene #124: 'TYRP1 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	132	109	109	133	30
TYRP1 MUTATED	0	2	0	1	1
TYRP1 WILD-TYPE	132	107	109	132	29

'TYRP1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.273 (Fisher's exact test), Q value = 0.9

Table S1184. Gene #124: 'TYRP1 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	134	71	36	66	91	41	74
TYRP1 MUTATED	1	1	1	0	0	1	0
TYRP1 WILD-TYPE	133	70	35	66	91	40	74

'TYRP1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.402 (Fisher's exact test), Q value = 1

Table S1185. Gene #124: 'TYRP1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
TYRP1 MUTATED	0	2	2	0
TYRP1 WILD-TYPE	136	105	181	83

'TYRP1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.344 (Fisher's exact test), Q value = 0.95

Table S1186. Gene #124: 'TYRP1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
TYRP1 MUTATED	1	1	2
TYRP1 WILD-TYPE	221	183	101

'TYRP1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.698 (Fisher's exact test), Q value = 1

Table S1187. Gene #124: 'TYRP1 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
TYRP1 MUTATED	1	1	2
TYRP1 WILD-TYPE	183	161	157

'TYRP1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.357 (Fisher's exact test), Q value = 0.97

Table S1188. Gene #124: 'TYRP1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
TYRP1 MUTATED	0	0	3	1
TYRP1 WILD-TYPE	90	138	185	88

'SLC25A5 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.456 (Fisher's exact test), Q value = 1

Table S1189. Gene #125: 'SLC25A5 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	169	120	221
SLC25A5 MUTATED	1	2	1
SLC25A5 WILD-TYPE	168	118	220

'SLC25A5 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.229 (Fisher's exact test), Q value = 0.86

Table S1190. Gene #125: 'SLC25A5 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	222	81	168	42
SLC25A5 MUTATED	2	1	0	1
SLC25A5 WILD-TYPE	220	80	168	41

'SLC25A5 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.928 (Fisher's exact test), Q value = 1

Table S1191. Gene #125: 'SLC25A5 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	132	109	109	133	30
SLC25A5 MUTATED	1	1	0	2	0
SLC25A5 WILD-TYPE	131	108	109	131	30

'SLC25A5 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.423 (Fisher's exact test), Q value = 1

Table S1192. Gene #125: 'SLC25A5 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	134	71	36	66	91	41	74
SLC25A5 MUTATED	1	0	0	2	0	0	1
SLC25A5 WILD-TYPE	133	71	36	64	91	41	73

'SLC25A5 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.834 (Fisher's exact test), Q value = 1

Table S1193. Gene #125: 'SLC25A5 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
SLC25A5 MUTATED	1	0	2	1
SLC25A5 WILD-TYPE	135	107	181	82

'SLC25A5 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.684 (Fisher's exact test), Q value = 1

Table S1194. Gene #125: 'SLC25A5 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
SLC25A5 MUTATED	1	2	1
SLC25A5 WILD-TYPE	221	182	102

'SLC25A5 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.472 (Fisher's exact test), Q value = 1

Table S1195. Gene #125: 'SLC25A5 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
SLC25A5 MUTATED	2	0	2
SLC25A5 WILD-TYPE	182	162	157

'SLC25A5 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.525 (Fisher's exact test), Q value = 1

Table S1196. Gene #125: 'SLC25A5 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
SLC25A5 MUTATED	1	0	2	1
SLC25A5 WILD-TYPE	89	138	186	88

'AGBL1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.167 (Fisher's exact test), Q value = 0.78

Table S1197. Gene #126: 'AGBL1 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	169	120	221
AGBL1 MUTATED	1	3	1
AGBL1 WILD-TYPE	168	117	220

'AGBL1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.116 (Fisher's exact test), Q value = 0.64

Table S1198. Gene #126: 'AGBL1 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	222	81	168	42
AGBL1 MUTATED	1	3	1	0
AGBL1 WILD-TYPE	221	78	167	42

'AGBL1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.442 (Fisher's exact test), Q value = 1

Table S1199. Gene #126: 'AGBL1 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	52	62	68	74
AGBL1 MUTATED	0	1	2	0
AGBL1 WILD-TYPE	52	61	66	74

'AGBL1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.43 (Fisher's exact test), Q value = 1

Table S1200. Gene #126: 'AGBL1 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	67	131	58
AGBL1 MUTATED	0	3	0
AGBL1 WILD-TYPE	67	128	58

'AGBL1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.031 (Fisher's exact test), Q value = 0.29

Table S1201. Gene #126: 'AGBL1 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	132	109	109	133	30
AGBL1 MUTATED	0	4	1	0	0
AGBL1 WILD-TYPE	132	105	108	133	30

Figure S202. Get High-res Image Gene #126: 'AGBL1 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

'AGBL1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0432 (Fisher's exact test), Q value = 0.37

Table S1202. Gene #126: 'AGBL1 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	134	71	36	66	91	41	74
AGBL1 MUTATED	0	2	0	0	1	2	0
AGBL1 WILD-TYPE	134	69	36	66	90	39	74

Figure S203. Get High-res Image Gene #126: 'AGBL1 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'AGBL1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.209 (Fisher's exact test), Q value = 0.85

Table S1203. Gene #126: 'AGBL1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
AGBL1 MUTATED	2	2	0	1
AGBL1 WILD-TYPE	134	105	183	82

'AGBL1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.00688 (Fisher's exact test), Q value = 0.1

Table S1204. Gene #126: 'AGBL1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
AGBL1 MUTATED	1	0	4
AGBL1 WILD-TYPE	221	184	99

Figure S204. Get High-res Image Gene #126: 'AGBL1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

'AGBL1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.135 (Fisher's exact test), Q value = 0.71

Table S1205. Gene #126: 'AGBL1 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
AGBL1 MUTATED	4	1	0
AGBL1 WILD-TYPE	180	161	159

'AGBL1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.00297 (Fisher's exact test), Q value = 0.053

Table S1206. Gene #126: 'AGBL1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
AGBL1 MUTATED	0	1	0	4
AGBL1 WILD-TYPE	90	137	188	85

Figure S205. Get High-res Image Gene #126: 'AGBL1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

'AMPD1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0556 (Fisher's exact test), Q value = 0.42

Table S1207. Gene #127: 'AMPD1 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	169	120	221
AMPD1 MUTATED	0	3	1
AMPD1 WILD-TYPE	169	117	220

'AMPD1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.202 (Fisher's exact test), Q value = 0.85

Table S1208. Gene #127: 'AMPD1 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	222	81	168	42
AMPD1 MUTATED	2	2	0	0
AMPD1 WILD-TYPE	220	79	168	42

'AMPD1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.926 (Fisher's exact test), Q value = 1

Table S1209. Gene #127: 'AMPD1 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	132	109	109	133	30
AMPD1 MUTATED	1	1	0	2	0
AMPD1 WILD-TYPE	131	108	109	131	30

'AMPD1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00792 (Fisher's exact test), Q value = 0.11

Table S1210. Gene #127: 'AMPD1 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	134	71	36	66	91	41	74
AMPD1 MUTATED	0	0	0	2	0	2	0
AMPD1 WILD-TYPE	134	71	36	64	91	39	74

Figure S206. Get High-res Image Gene #127: 'AMPD1 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'AMPD1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.4 (Fisher's exact test), Q value = 1

Table S1211. Gene #127: 'AMPD1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
AMPD1 MUTATED	0	2	2	0
AMPD1 WILD-TYPE	136	105	181	83

'AMPD1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.341 (Fisher's exact test), Q value = 0.95

Table S1212. Gene #127: 'AMPD1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
AMPD1 MUTATED	1	1	2
AMPD1 WILD-TYPE	221	183	101

'AMPD1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.165 (Fisher's exact test), Q value = 0.78

Table S1213. Gene #127: 'AMPD1 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
AMPD1 MUTATED	1	0	3
AMPD1 WILD-TYPE	183	162	156

'AMPD1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.917 (Fisher's exact test), Q value = 1

Table S1214. Gene #127: 'AMPD1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
AMPD1 MUTATED	0	1	2	1
AMPD1 WILD-TYPE	90	137	186	88

'NGEF MUTATION STATUS' versus 'CN_CNMF'

P value = 0.872 (Fisher's exact test), Q value = 1

Table S1215. Gene #128: 'NGEF MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	169	120	221
NGEF MUTATED	2	2	2
NGEF WILD-TYPE	167	118	219

'NGEF MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.64 (Fisher's exact test), Q value = 1

Table S1216. Gene #128: 'NGEF MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	222	81	168	42
NGEF MUTATED	2	2	2	0
NGEF WILD-TYPE	220	79	166	42

'NGEF MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.239 (Fisher's exact test), Q value = 0.88

Table S1217. Gene #128: 'NGEF MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	52	62	68	74
NGEF MUTATED	1	0	2	0
NGEF WILD-TYPE	51	62	66	74

'NGEF MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S1218. Gene #128: 'NGEF MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	67	131	58
NGEF MUTATED	1	2	0
NGEF WILD-TYPE	66	129	58

'NGEF MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.715 (Fisher's exact test), Q value = 1

Table S1219. Gene #128: 'NGEF MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	132	109	109	133	30
NGEF MUTATED	2	1	1	1	1
NGEF WILD-TYPE	130	108	108	132	29

'NGEF MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.923 (Fisher's exact test), Q value = 1

Table S1220. Gene #128: 'NGEF MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	134	71	36	66	91	41	74
NGEF MUTATED	2	0	0	1	1	1	1
NGEF WILD-TYPE	132	71	36	65	90	40	73

'NGEF MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.431 (Fisher's exact test), Q value = 1

Table S1221. Gene #128: 'NGEF MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
NGEF MUTATED	0	2	3	1
NGEF WILD-TYPE	136	105	180	82

'NGEF MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.869 (Fisher's exact test), Q value = 1

Table S1222. Gene #128: 'NGEF MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
NGEF MUTATED	2	3	1
NGEF WILD-TYPE	220	181	102

'NGEF MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.293 (Fisher's exact test), Q value = 0.92

Table S1223. Gene #128: 'NGEF MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
NGEF MUTATED	1	1	4
NGEF WILD-TYPE	183	161	155

'NGEF MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.412 (Fisher's exact test), Q value = 1

Table S1224. Gene #128: 'NGEF MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
NGEF MUTATED	0	2	4	0
NGEF WILD-TYPE	90	136	184	89

'YIPF1 MUTATION STATUS' versus 'CN_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1225. Gene #129: 'YIPF1 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	169	120	221
YIPF1 MUTATED	1	1	1
YIPF1 WILD-TYPE	168	119	220

'YIPF1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.675 (Fisher's exact test), Q value = 1

Table S1226. Gene #129: 'YIPF1 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	222	81	168	42
YIPF1 MUTATED	1	1	1	0
YIPF1 WILD-TYPE	221	80	167	42

'YIPF1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.561 (Fisher's exact test), Q value = 1

Table S1227. Gene #129: 'YIPF1 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	52	62	68	74
YIPF1 MUTATED	0	0	2	1
YIPF1 WILD-TYPE	52	62	66	73

'YIPF1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S1228. Gene #129: 'YIPF1 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	67	131	58
YIPF1 MUTATED	1	2	0
YIPF1 WILD-TYPE	66	129	58

'YIPF1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0835 (Fisher's exact test), Q value = 0.52

Table S1229. Gene #129: 'YIPF1 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	132	109	109	133	30
YIPF1 MUTATED	0	1	1	0	1
YIPF1 WILD-TYPE	132	108	108	133	29

'YIPF1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0543 (Fisher's exact test), Q value = 0.42

Table S1230. Gene #129: 'YIPF1 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	134	71	36	66	91	41	74
YIPF1 MUTATED	0	0	1	1	0	1	0
YIPF1 WILD-TYPE	134	71	35	65	91	40	74

'YIPF1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.522 (Fisher's exact test), Q value = 1

Table S1231. Gene #129: 'YIPF1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
YIPF1 MUTATED	0	1	1	1
YIPF1 WILD-TYPE	136	106	182	82

'YIPF1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.792 (Fisher's exact test), Q value = 1

Table S1232. Gene #129: 'YIPF1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
YIPF1 MUTATED	1	1	1
YIPF1 WILD-TYPE	221	183	102

'YIPF1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.208 (Fisher's exact test), Q value = 0.85

Table S1233. Gene #129: 'YIPF1 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
YIPF1 MUTATED	0	1	2
YIPF1 WILD-TYPE	184	161	157

'YIPF1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S1234. Gene #129: 'YIPF1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
YIPF1 MUTATED	0	1	2	0
YIPF1 WILD-TYPE	90	137	186	89

'PDHA1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.208 (Fisher's exact test), Q value = 0.85

Table S1235. Gene #130: 'PDHA1 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	169	120	221
PDHA1 MUTATED	0	1	4
PDHA1 WILD-TYPE	169	119	217

'PDHA1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.512 (Fisher's exact test), Q value = 1

Table S1236. Gene #130: 'PDHA1 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	222	81	168	42
PDHA1 MUTATED	1	1	3	0
PDHA1 WILD-TYPE	221	80	165	42

'PDHA1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.0531 (Fisher's exact test), Q value = 0.42

Table S1237. Gene #130: 'PDHA1 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	52	62	68	74
PDHA1 MUTATED	1	3	0	0
PDHA1 WILD-TYPE	51	59	68	74

'PDHA1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.811 (Fisher's exact test), Q value = 1

Table S1238. Gene #130: 'PDHA1 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	67	131	58
PDHA1 MUTATED	1	3	0
PDHA1 WILD-TYPE	66	128	58

'PDHA1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.676 (Fisher's exact test), Q value = 1

Table S1239. Gene #130: 'PDHA1 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	132	109	109	133	30
PDHA1 MUTATED	1	1	1	1	1
PDHA1 WILD-TYPE	131	108	108	132	29

'PDHA1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.459 (Fisher's exact test), Q value = 1

Table S1240. Gene #130: 'PDHA1 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	134	71	36	66	91	41	74
PDHA1 MUTATED	1	1	0	0	3	0	0
PDHA1 WILD-TYPE	133	70	36	66	88	41	74

'PDHA1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.928 (Fisher's exact test), Q value = 1

Table S1241. Gene #130: 'PDHA1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
PDHA1 MUTATED	2	1	2	0
PDHA1 WILD-TYPE	134	106	181	83

'PDHA1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.848 (Fisher's exact test), Q value = 1

Table S1242. Gene #130: 'PDHA1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
PDHA1 MUTATED	3	1	1
PDHA1 WILD-TYPE	219	183	102

'PDHA1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.532 (Fisher's exact test), Q value = 1

Table S1243. Gene #130: 'PDHA1 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
PDHA1 MUTATED	1	3	1
PDHA1 WILD-TYPE	183	159	158

'PDHA1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.397 (Fisher's exact test), Q value = 1

Table S1244. Gene #130: 'PDHA1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
PDHA1 MUTATED	0	3	1	1
PDHA1 WILD-TYPE	90	135	187	88

'ASXL2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.467 (Fisher's exact test), Q value = 1

Table S1245. Gene #131: 'ASXL2 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	169	120	221
ASXL2 MUTATED	0	1	2
ASXL2 WILD-TYPE	169	119	219

'ASXL2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.302 (Fisher's exact test), Q value = 0.93

Table S1246. Gene #131: 'ASXL2 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	222	81	168	42
ASXL2 MUTATED	0	1	2	0
ASXL2 WILD-TYPE	222	80	166	42

'ASXL2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.83 (Fisher's exact test), Q value = 1

Table S1247. Gene #131: 'ASXL2 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	132	109	109	133	30
ASXL2 MUTATED	0	1	1	1	0
ASXL2 WILD-TYPE	132	108	108	132	30

'ASXL2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.318 (Fisher's exact test), Q value = 0.95

Table S1248. Gene #131: 'ASXL2 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	134	71	36	66	91	41	74
ASXL2 MUTATED	0	0	0	0	1	1	1
ASXL2 WILD-TYPE	134	71	36	66	90	40	73

'ASXL2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.521 (Fisher's exact test), Q value = 1

Table S1249. Gene #131: 'ASXL2 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
ASXL2 MUTATED	0	1	1	1
ASXL2 WILD-TYPE	136	106	182	82

'ASXL2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.793 (Fisher's exact test), Q value = 1

Table S1250. Gene #131: 'ASXL2 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
ASXL2 MUTATED	1	1	1
ASXL2 WILD-TYPE	221	183	102

'ASXL2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.205 (Fisher's exact test), Q value = 0.85

Table S1251. Gene #131: 'ASXL2 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
ASXL2 MUTATED	0	1	2
ASXL2 WILD-TYPE	184	161	157

'ASXL2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S1252. Gene #131: 'ASXL2 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
ASXL2 MUTATED	0	1	2	0
ASXL2 WILD-TYPE	90	137	186	89

'HLA-DRA MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0126 (Fisher's exact test), Q value = 0.16

Table S1253. Gene #132: 'HLA-DRA MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	169	120	221
HLA-DRA MUTATED	0	3	0
HLA-DRA WILD-TYPE	169	117	221

Figure S207. Get High-res Image Gene #132: 'HLA-DRA MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

'HLA-DRA MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.542 (Fisher's exact test), Q value = 1

Table S1254. Gene #132: 'HLA-DRA MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	222	81	168	42
HLA-DRA MUTATED	2	1	0	0
HLA-DRA WILD-TYPE	220	80	168	42

'HLA-DRA MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.346 (Fisher's exact test), Q value = 0.95

Table S1255. Gene #132: 'HLA-DRA MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	132	109	109	133	30
HLA-DRA MUTATED	1	2	0	0	0
HLA-DRA WILD-TYPE	131	107	109	133	30

'HLA-DRA MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0727 (Fisher's exact test), Q value = 0.5

Table S1256. Gene #132: 'HLA-DRA MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	134	71	36	66	91	41	74
HLA-DRA MUTATED	1	0	0	0	0	2	0
HLA-DRA WILD-TYPE	133	71	36	66	91	39	74

'HLA-DRA MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.188 (Fisher's exact test), Q value = 0.82

Table S1257. Gene #132: 'HLA-DRA MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
HLA-DRA MUTATED	1	2	0	0
HLA-DRA WILD-TYPE	135	105	183	83

'HLA-DRA MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.154 (Fisher's exact test), Q value = 0.76

Table S1258. Gene #132: 'HLA-DRA MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
HLA-DRA MUTATED	1	0	2
HLA-DRA WILD-TYPE	221	184	101

'HLA-DRA MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.306 (Fisher's exact test), Q value = 0.93

Table S1259. Gene #132: 'HLA-DRA MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
HLA-DRA MUTATED	0	2	1
HLA-DRA WILD-TYPE	184	160	158

'HLA-DRA MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.777 (Fisher's exact test), Q value = 1

Table S1260. Gene #132: 'HLA-DRA MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
HLA-DRA MUTATED	0	1	1	1
HLA-DRA WILD-TYPE	90	137	187	88

'ALPP MUTATION STATUS' versus 'CN_CNMF'

P value = 0.531 (Fisher's exact test), Q value = 1

Table S1261. Gene #133: 'ALPP MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	169	120	221
ALPP MUTATED	2	2	1
ALPP WILD-TYPE	167	118	220

'ALPP MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.466 (Fisher's exact test), Q value = 1

Table S1262. Gene #133: 'ALPP MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	222	81	168	42
ALPP MUTATED	2	2	1	0
ALPP WILD-TYPE	220	79	167	42

'ALPP MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.00058 (Fisher's exact test), Q value = 0.014

Table S1263. Gene #133: 'ALPP MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	132	109	109	133	30
ALPP MUTATED	0	1	1	0	3
ALPP WILD-TYPE	132	108	108	133	27

Figure S208. Get High-res Image Gene #133: 'ALPP MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

'ALPP MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.582 (Fisher's exact test), Q value = 1

Table S1264. Gene #133: 'ALPP MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	134	71	36	66	91	41	74
ALPP MUTATED	2	1	1	1	0	0	0
ALPP WILD-TYPE	132	70	35	65	91	41	74

'ALPP MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.374 (Fisher's exact test), Q value = 1

Table S1265. Gene #133: 'ALPP MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
ALPP MUTATED	3	0	2	0
ALPP WILD-TYPE	133	107	181	83

'ALPP MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.847 (Fisher's exact test), Q value = 1

Table S1266. Gene #133: 'ALPP MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
ALPP MUTATED	3	1	1
ALPP WILD-TYPE	219	183	102

'ALPP MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.53 (Fisher's exact test), Q value = 1

Table S1267. Gene #133: 'ALPP MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
ALPP MUTATED	1	3	1
ALPP WILD-TYPE	183	159	158

'ALPP MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.818 (Fisher's exact test), Q value = 1

Table S1268. Gene #133: 'ALPP MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
ALPP MUTATED	1	2	1	1
ALPP WILD-TYPE	89	136	187	88

'CDH3 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.176 (Fisher's exact test), Q value = 0.8

Table S1269. Gene #134: 'CDH3 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	169	120	221
CDH3 MUTATED	0	2	1
CDH3 WILD-TYPE	169	118	220

'CDH3 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.675 (Fisher's exact test), Q value = 1

Table S1270. Gene #134: 'CDH3 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	222	81	168	42
CDH3 MUTATED	1	1	1	0
CDH3 WILD-TYPE	221	80	167	42

'CDH3 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.829 (Fisher's exact test), Q value = 1

Table S1271. Gene #134: 'CDH3 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	132	109	109	133	30
CDH3 MUTATED	0	1	1	1	0
CDH3 WILD-TYPE	132	108	108	132	30

'CDH3 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.281 (Fisher's exact test), Q value = 0.91

Table S1272. Gene #134: 'CDH3 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	134	71	36	66	91	41	74
CDH3 MUTATED	0	0	0	1	1	1	0
CDH3 WILD-TYPE	134	71	36	65	90	40	74

'CDH3 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.523 (Fisher's exact test), Q value = 1

Table S1273. Gene #134: 'CDH3 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
CDH3 MUTATED	0	1	1	1
CDH3 WILD-TYPE	136	106	182	82

'CDH3 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.795 (Fisher's exact test), Q value = 1

Table S1274. Gene #134: 'CDH3 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
CDH3 MUTATED	1	1	1
CDH3 WILD-TYPE	221	183	102

'CDH3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.21 (Fisher's exact test), Q value = 0.85

Table S1275. Gene #134: 'CDH3 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
CDH3 MUTATED	0	1	2
CDH3 WILD-TYPE	184	161	157

'CDH3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S1276. Gene #134: 'CDH3 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
CDH3 MUTATED	0	1	2	0
CDH3 WILD-TYPE	90	137	186	89

'NADSYN1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.104 (Fisher's exact test), Q value = 0.61

Table S1277. Gene #135: 'NADSYN1 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	169	120	221
NADSYN1 MUTATED	1	2	0
NADSYN1 WILD-TYPE	168	118	221

'NADSYN1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.539 (Fisher's exact test), Q value = 1

Table S1278. Gene #135: 'NADSYN1 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	222	81	168	42
NADSYN1 MUTATED	2	1	0	0
NADSYN1 WILD-TYPE	220	80	168	42

'NADSYN1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.344 (Fisher's exact test), Q value = 0.95

Table S1279. Gene #135: 'NADSYN1 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	132	109	109	133	30
NADSYN1 MUTATED	1	2	0	0	0
NADSYN1 WILD-TYPE	131	107	109	133	30

'NADSYN1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0735 (Fisher's exact test), Q value = 0.5

Table S1280. Gene #135: 'NADSYN1 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	134	71	36	66	91	41	74
NADSYN1 MUTATED	1	0	0	0	0	2	0
NADSYN1 WILD-TYPE	133	71	36	66	91	39	74

'NADSYN1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.384 (Fisher's exact test), Q value = 1

Table S1281. Gene #135: 'NADSYN1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
NADSYN1 MUTATED	1	1	0	1
NADSYN1 WILD-TYPE	135	106	183	82

'NADSYN1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.154 (Fisher's exact test), Q value = 0.76

Table S1282. Gene #135: 'NADSYN1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
NADSYN1 MUTATED	1	0	2
NADSYN1 WILD-TYPE	221	184	101

'NADSYN1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.648 (Fisher's exact test), Q value = 1

Table S1283. Gene #135: 'NADSYN1 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
NADSYN1 MUTATED	2	0	1
NADSYN1 WILD-TYPE	182	162	158

'NADSYN1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.437 (Fisher's exact test), Q value = 1

Table S1284. Gene #135: 'NADSYN1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
NADSYN1 MUTATED	1	0	1	1
NADSYN1 WILD-TYPE	89	138	187	88

'LHFPL1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.69 (Fisher's exact test), Q value = 1

Table S1285. Gene #136: 'LHFPL1 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	169	120	221
LHFPL1 MUTATED	2	0	2
LHFPL1 WILD-TYPE	167	120	219

'LHFPL1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1286. Gene #136: 'LHFPL1 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	222	81	168	42
LHFPL1 MUTATED	2	0	2	0
LHFPL1 WILD-TYPE	220	81	166	42

'LHFPL1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.279 (Fisher's exact test), Q value = 0.9

Table S1287. Gene #136: 'LHFPL1 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	132	109	109	133	30
LHFPL1 MUTATED	0	0	1	3	0
LHFPL1 WILD-TYPE	132	109	108	130	30

'LHFPL1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.323 (Fisher's exact test), Q value = 0.95

Table S1288. Gene #136: 'LHFPL1 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	134	71	36	66	91	41	74
LHFPL1 MUTATED	0	0	0	1	1	0	2
LHFPL1 WILD-TYPE	134	71	36	65	90	41	72

'LHFPL1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.304 (Fisher's exact test), Q value = 0.93

Table S1289. Gene #136: 'LHFPL1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
LHFPL1 MUTATED	0	0	3	1
LHFPL1 WILD-TYPE	136	107	180	82

'LHFPL1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.423 (Fisher's exact test), Q value = 1

Table S1290. Gene #136: 'LHFPL1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
LHFPL1 MUTATED	1	3	0
LHFPL1 WILD-TYPE	221	181	103

'LHFPL1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.077 (Fisher's exact test), Q value = 0.51

Table S1291. Gene #136: 'LHFPL1 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
LHFPL1 MUTATED	0	1	3
LHFPL1 WILD-TYPE	184	161	156

'LHFPL1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.579 (Fisher's exact test), Q value = 1

Table S1292. Gene #136: 'LHFPL1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
LHFPL1 MUTATED	0	1	3	0
LHFPL1 WILD-TYPE	90	137	185	89

'SLC10A7 MUTATION STATUS' versus 'CN_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1293. Gene #137: 'SLC10A7 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	169	120	221
SLC10A7 MUTATED	1	1	1
SLC10A7 WILD-TYPE	168	119	220

'SLC10A7 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.54 (Fisher's exact test), Q value = 1

Table S1294. Gene #137: 'SLC10A7 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	222	81	168	42
SLC10A7 MUTATED	2	1	0	0
SLC10A7 WILD-TYPE	220	80	168	42

'SLC10A7 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.499 (Fisher's exact test), Q value = 1

Table S1295. Gene #137: 'SLC10A7 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	132	109	109	133	30
SLC10A7 MUTATED	2	1	0	0	0
SLC10A7 WILD-TYPE	130	108	109	133	30

'SLC10A7 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.496 (Fisher's exact test), Q value = 1

Table S1296. Gene #137: 'SLC10A7 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	134	71	36	66	91	41	74
SLC10A7 MUTATED	2	0	0	0	0	1	0
SLC10A7 WILD-TYPE	132	71	36	66	91	40	74

'SLC10A7 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.191 (Fisher's exact test), Q value = 0.83

Table S1297. Gene #137: 'SLC10A7 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
SLC10A7 MUTATED	1	2	0	0
SLC10A7 WILD-TYPE	135	105	183	83

'SLC10A7 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.43 (Fisher's exact test), Q value = 1

Table S1298. Gene #137: 'SLC10A7 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
SLC10A7 MUTATED	2	0	1
SLC10A7 WILD-TYPE	220	184	102

'SLC10A7 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1299. Gene #137: 'SLC10A7 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
SLC10A7 MUTATED	1	1	1
SLC10A7 WILD-TYPE	183	161	158

'SLC10A7 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.887 (Fisher's exact test), Q value = 1

Table S1300. Gene #137: 'SLC10A7 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
SLC10A7 MUTATED	1	1	1	0
SLC10A7 WILD-TYPE	89	137	187	89

'CXCR2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.688 (Fisher's exact test), Q value = 1

Table S1301. Gene #138: 'CXCR2 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	169	120	221
CXCR2 MUTATED	2	0	2
CXCR2 WILD-TYPE	167	120	219

'CXCR2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.759 (Fisher's exact test), Q value = 1

Table S1302. Gene #138: 'CXCR2 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	222	81	168	42
CXCR2 MUTATED	3	0	1	0
CXCR2 WILD-TYPE	219	81	167	42

'CXCR2 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.673 (Fisher's exact test), Q value = 1

Table S1303. Gene #138: 'CXCR2 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	52	62	68	74
CXCR2 MUTATED	1	0	2	1
CXCR2 WILD-TYPE	51	62	66	73

'CXCR2 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S1304. Gene #138: 'CXCR2 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	67	131	58
CXCR2 MUTATED	1	2	1
CXCR2 WILD-TYPE	66	129	57

'CXCR2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.488 (Fisher's exact test), Q value = 1

Table S1305. Gene #138: 'CXCR2 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	132	109	109	133	30
CXCR2 MUTATED	2	0	0	2	0
CXCR2 WILD-TYPE	130	109	109	131	30

'CXCR2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.298 (Fisher's exact test), Q value = 0.93

Table S1306. Gene #138: 'CXCR2 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	134	71	36	66	91	41	74
CXCR2 MUTATED	1	0	0	0	0	1	2
CXCR2 WILD-TYPE	133	71	36	66	91	40	72

'CXCR2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1307. Gene #138: 'CXCR2 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
CXCR2 MUTATED	1	1	2	0
CXCR2 WILD-TYPE	135	106	181	83

'CXCR2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.683 (Fisher's exact test), Q value = 1

Table S1308. Gene #138: 'CXCR2 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
CXCR2 MUTATED	1	2	1
CXCR2 WILD-TYPE	221	182	102

'CXCR2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.078 (Fisher's exact test), Q value = 0.51

Table S1309. Gene #138: 'CXCR2 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
CXCR2 MUTATED	0	1	3
CXCR2 WILD-TYPE	184	161	156

'CXCR2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.394 (Fisher's exact test), Q value = 1

Table S1310. Gene #138: 'CXCR2 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
CXCR2 MUTATED	1	0	3	0
CXCR2 WILD-TYPE	89	138	185	89

'SEC14L4 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.609 (Fisher's exact test), Q value = 1

Table S1311. Gene #139: 'SEC14L4 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	169	120	221
SEC14L4 MUTATED	2	0	1
SEC14L4 WILD-TYPE	167	120	220

'SEC14L4 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.541 (Fisher's exact test), Q value = 1

Table S1312. Gene #139: 'SEC14L4 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	222	81	168	42
SEC14L4 MUTATED	2	1	0	0
SEC14L4 WILD-TYPE	220	80	168	42

'SEC14L4 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.344 (Fisher's exact test), Q value = 0.95

Table S1313. Gene #139: 'SEC14L4 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	132	109	109	133	30
SEC14L4 MUTATED	1	2	0	0	0
SEC14L4 WILD-TYPE	131	107	109	133	30

'SEC14L4 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.515 (Fisher's exact test), Q value = 1

Table S1314. Gene #139: 'SEC14L4 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	134	71	36	66	91	41	74
SEC14L4 MUTATED	1	1	0	0	0	1	0
SEC14L4 WILD-TYPE	133	70	36	66	91	40	74

'SEC14L4 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.19 (Fisher's exact test), Q value = 0.83

Table S1315. Gene #139: 'SEC14L4 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
SEC14L4 MUTATED	1	2	0	0
SEC14L4 WILD-TYPE	135	105	183	83

'SEC14L4 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.153 (Fisher's exact test), Q value = 0.76

Table S1316. Gene #139: 'SEC14L4 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
SEC14L4 MUTATED	1	0	2
SEC14L4 WILD-TYPE	221	184	101

'SEC14L4 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.112 (Fisher's exact test), Q value = 0.63

Table S1317. Gene #139: 'SEC14L4 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
SEC14L4 MUTATED	3	0	0
SEC14L4 WILD-TYPE	181	162	159

'SEC14L4 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.0272 (Fisher's exact test), Q value = 0.27

Table S1318. Gene #139: 'SEC14L4 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
SEC14L4 MUTATED	1	0	0	2
SEC14L4 WILD-TYPE	89	138	188	87

Figure S209. Get High-res Image Gene #139: 'SEC14L4 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

'ANKRD17 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.143 (Fisher's exact test), Q value = 0.73

Table S1319. Gene #140: 'ANKRD17 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	169	120	221
ANKRD17 MUTATED	0	2	4
ANKRD17 WILD-TYPE	169	118	217

'ANKRD17 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.321 (Fisher's exact test), Q value = 0.95

Table S1320. Gene #140: 'ANKRD17 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	222	81	168	42
ANKRD17 MUTATED	1	1	4	0
ANKRD17 WILD-TYPE	221	80	164	42

'ANKRD17 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.413 (Fisher's exact test), Q value = 1

Table S1321. Gene #140: 'ANKRD17 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	52	62	68	74
ANKRD17 MUTATED	0	0	2	2
ANKRD17 WILD-TYPE	52	62	66	72

'ANKRD17 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.262 (Fisher's exact test), Q value = 0.89

Table S1322. Gene #140: 'ANKRD17 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	67	131	58
ANKRD17 MUTATED	0	2	2
ANKRD17 WILD-TYPE	67	129	56

'ANKRD17 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.962 (Fisher's exact test), Q value = 1

Table S1323. Gene #140: 'ANKRD17 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	132	109	109	133	30
ANKRD17 MUTATED	1	1	2	2	0
ANKRD17 WILD-TYPE	131	108	107	131	30

'ANKRD17 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.397 (Fisher's exact test), Q value = 1

Table S1324. Gene #140: 'ANKRD17 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	134	71	36	66	91	41	74
ANKRD17 MUTATED	1	0	1	0	1	1	2
ANKRD17 WILD-TYPE	133	71	35	66	90	40	72

'ANKRD17 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.844 (Fisher's exact test), Q value = 1

Table S1325. Gene #140: 'ANKRD17 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
ANKRD17 MUTATED	2	1	3	0
ANKRD17 WILD-TYPE	134	106	180	83

'ANKRD17 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.867 (Fisher's exact test), Q value = 1

Table S1326. Gene #140: 'ANKRD17 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
ANKRD17 MUTATED	2	3	1
ANKRD17 WILD-TYPE	220	181	102

'ANKRD17 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.0684 (Fisher's exact test), Q value = 0.48

Table S1327. Gene #140: 'ANKRD17 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
ANKRD17 MUTATED	0	2	4
ANKRD17 WILD-TYPE	184	160	155

'ANKRD17 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.523 (Fisher's exact test), Q value = 1

Table S1328. Gene #140: 'ANKRD17 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
ANKRD17 MUTATED	1	1	4	0
ANKRD17 WILD-TYPE	89	137	184	89

'MAST3 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.852 (Fisher's exact test), Q value = 1

Table S1329. Gene #141: 'MAST3 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	169	120	221
MAST3 MUTATED	1	1	3
MAST3 WILD-TYPE	168	119	218

'MAST3 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.376 (Fisher's exact test), Q value = 1

Table S1330. Gene #141: 'MAST3 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	222	81	168	42
MAST3 MUTATED	1	1	2	1
MAST3 WILD-TYPE	221	80	166	41

'MAST3 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.342 (Fisher's exact test), Q value = 0.95

Table S1331. Gene #141: 'MAST3 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	132	109	109	133	30
MAST3 MUTATED	0	1	1	2	1
MAST3 WILD-TYPE	132	108	108	131	29

'MAST3 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.455 (Fisher's exact test), Q value = 1

Table S1332. Gene #141: 'MAST3 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	134	71	36	66	91	41	74
MAST3 MUTATED	0	1	0	1	1	0	2
MAST3 WILD-TYPE	134	70	36	65	90	41	72

'MAST3 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.491 (Fisher's exact test), Q value = 1

Table S1333. Gene #141: 'MAST3 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
MAST3 MUTATED	0	1	3	1
MAST3 WILD-TYPE	136	106	180	82

'MAST3 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.44 (Fisher's exact test), Q value = 1

Table S1334. Gene #141: 'MAST3 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
MAST3 MUTATED	1	3	1
MAST3 WILD-TYPE	221	181	102

'MAST3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.455 (Fisher's exact test), Q value = 1

Table S1335. Gene #141: 'MAST3 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
MAST3 MUTATED	1	1	3
MAST3 WILD-TYPE	183	161	156

'MAST3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.716 (Fisher's exact test), Q value = 1

Table S1336. Gene #141: 'MAST3 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
MAST3 MUTATED	0	1	3	1
MAST3 WILD-TYPE	90	137	185	88

'AMMECR1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.38 (Fisher's exact test), Q value = 1

Table S1337. Gene #142: 'AMMECR1 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	169	120	221
AMMECR1 MUTATED	3	0	2
AMMECR1 WILD-TYPE	166	120	219

'AMMECR1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.613 (Fisher's exact test), Q value = 1

Table S1338. Gene #142: 'AMMECR1 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	222	81	168	42
AMMECR1 MUTATED	2	0	2	1
AMMECR1 WILD-TYPE	220	81	166	41

'AMMECR1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.505 (Fisher's exact test), Q value = 1

Table S1339. Gene #142: 'AMMECR1 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	132	109	109	133	30
AMMECR1 MUTATED	0	2	2	1	0
AMMECR1 WILD-TYPE	132	107	107	132	30

'AMMECR1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0492 (Fisher's exact test), Q value = 0.4

Table S1340. Gene #142: 'AMMECR1 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	134	71	36	66	91	41	74
AMMECR1 MUTATED	0	0	1	0	1	2	1
AMMECR1 WILD-TYPE	134	71	35	66	90	39	73

Figure S210. Get High-res Image Gene #142: 'AMMECR1 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'AMMECR1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.165 (Fisher's exact test), Q value = 0.78

Table S1341. Gene #142: 'AMMECR1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
AMMECR1 MUTATED	0	2	1	2
AMMECR1 WILD-TYPE	136	105	182	81

'AMMECR1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.526 (Fisher's exact test), Q value = 1

Table S1342. Gene #142: 'AMMECR1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
AMMECR1 MUTATED	2	1	2
AMMECR1 WILD-TYPE	220	183	101

'AMMECR1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.198 (Fisher's exact test), Q value = 0.84

Table S1343. Gene #142: 'AMMECR1 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
AMMECR1 MUTATED	0	3	2
AMMECR1 WILD-TYPE	184	159	157

'AMMECR1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.451 (Fisher's exact test), Q value = 1

Table S1344. Gene #142: 'AMMECR1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
AMMECR1 MUTATED	0	3	2	0
AMMECR1 WILD-TYPE	90	135	186	89

'NEO1 MUTATION STATUS' versus 'CN_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1345. Gene #143: 'NEO1 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	169	120	221
NEO1 MUTATED	2	2	3
NEO1 WILD-TYPE	167	118	218

'NEO1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.736 (Fisher's exact test), Q value = 1

Table S1346. Gene #143: 'NEO1 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	222	81	168	42
NEO1 MUTATED	2	1	3	1
NEO1 WILD-TYPE	220	80	165	41

'NEO1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.415 (Fisher's exact test), Q value = 1

Table S1347. Gene #143: 'NEO1 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	52	62	68	74
NEO1 MUTATED	0	0	2	2
NEO1 WILD-TYPE	52	62	66	72

'NEO1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.261 (Fisher's exact test), Q value = 0.89

Table S1348. Gene #143: 'NEO1 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	67	131	58
NEO1 MUTATED	0	2	2
NEO1 WILD-TYPE	67	129	56

'NEO1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.71 (Fisher's exact test), Q value = 1

Table S1349. Gene #143: 'NEO1 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	132	109	109	133	30
NEO1 MUTATED	1	1	2	2	1
NEO1 WILD-TYPE	131	108	107	131	29

'NEO1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.821 (Fisher's exact test), Q value = 1

Table S1350. Gene #143: 'NEO1 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	134	71	36	66	91	41	74
NEO1 MUTATED	2	0	1	1	1	1	1
NEO1 WILD-TYPE	132	71	35	65	90	40	73

'NEO1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.77 (Fisher's exact test), Q value = 1

Table S1351. Gene #143: 'NEO1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
NEO1 MUTATED	2	2	3	0
NEO1 WILD-TYPE	134	105	180	83

'NEO1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S1352. Gene #143: 'NEO1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
NEO1 MUTATED	3	3	1
NEO1 WILD-TYPE	219	181	102

'NEO1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.0274 (Fisher's exact test), Q value = 0.27

Table S1353. Gene #143: 'NEO1 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
NEO1 MUTATED	0	2	5
NEO1 WILD-TYPE	184	160	154

Figure S211. Get High-res Image Gene #143: 'NEO1 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

'NEO1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.324 (Fisher's exact test), Q value = 0.95

Table S1354. Gene #143: 'NEO1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
NEO1 MUTATED	0	3	4	0
NEO1 WILD-TYPE	90	135	184	89

'IGSF8 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.362 (Fisher's exact test), Q value = 0.98

Table S1355. Gene #144: 'IGSF8 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	169	120	221
IGSF8 MUTATED	0	1	3
IGSF8 WILD-TYPE	169	119	218

'IGSF8 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.654 (Fisher's exact test), Q value = 1

Table S1356. Gene #144: 'IGSF8 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	222	81	168	42
IGSF8 MUTATED	1	1	2	0
IGSF8 WILD-TYPE	221	80	166	42

'IGSF8 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1357. Gene #144: 'IGSF8 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	132	109	109	133	30
IGSF8 MUTATED	1	1	1	1	0
IGSF8 WILD-TYPE	131	108	108	132	30

'IGSF8 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00711 (Fisher's exact test), Q value = 0.1

Table S1358. Gene #144: 'IGSF8 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	134	71	36	66	91	41	74
IGSF8 MUTATED	0	0	2	1	0	1	0
IGSF8 WILD-TYPE	134	71	34	65	91	40	74

Figure S212. Get High-res Image Gene #144: 'IGSF8 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'IGSF8 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.403 (Fisher's exact test), Q value = 1

Table S1359. Gene #144: 'IGSF8 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
IGSF8 MUTATED	0	2	2	0
IGSF8 WILD-TYPE	136	105	181	83

'IGSF8 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.151 (Fisher's exact test), Q value = 0.76

Table S1360. Gene #144: 'IGSF8 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
IGSF8 MUTATED	0	3	1
IGSF8 WILD-TYPE	222	181	102

'IGSF8 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.0774 (Fisher's exact test), Q value = 0.51

Table S1361. Gene #144: 'IGSF8 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
IGSF8 MUTATED	0	1	3
IGSF8 WILD-TYPE	184	161	156

'IGSF8 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.162 (Fisher's exact test), Q value = 0.78

Table S1362. Gene #144: 'IGSF8 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
IGSF8 MUTATED	0	0	4	0
IGSF8 WILD-TYPE	90	138	184	89

'PACS1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.334 (Fisher's exact test), Q value = 0.95

Table S1363. Gene #145: 'PACS1 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	169	120	221
PACS1 MUTATED	0	0	3
PACS1 WILD-TYPE	169	120	218

'PACS1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1364. Gene #145: 'PACS1 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	222	81	168	42
PACS1 MUTATED	2	0	1	0
PACS1 WILD-TYPE	220	81	167	42

'PACS1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.691 (Fisher's exact test), Q value = 1

Table S1365. Gene #145: 'PACS1 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	132	109	109	133	30
PACS1 MUTATED	1	0	0	2	0
PACS1 WILD-TYPE	131	109	109	131	30

'PACS1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.789 (Fisher's exact test), Q value = 1

Table S1366. Gene #145: 'PACS1 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	134	71	36	66	91	41	74
PACS1 MUTATED	1	0	0	1	0	0	1
PACS1 WILD-TYPE	133	71	36	65	91	41	73

'PACS1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.775 (Fisher's exact test), Q value = 1

Table S1367. Gene #145: 'PACS1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
PACS1 MUTATED	1	0	1	1
PACS1 WILD-TYPE	135	107	182	82

'PACS1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.601 (Fisher's exact test), Q value = 1

Table S1368. Gene #145: 'PACS1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
PACS1 MUTATED	1	2	0
PACS1 WILD-TYPE	221	182	103

'PACS1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1369. Gene #145: 'PACS1 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
PACS1 MUTATED	1	1	1
PACS1 WILD-TYPE	183	161	158

'PACS1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.888 (Fisher's exact test), Q value = 1

Table S1370. Gene #145: 'PACS1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
PACS1 MUTATED	1	1	1	0
PACS1 WILD-TYPE	89	137	187	89

'RGS3 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.379 (Fisher's exact test), Q value = 1

Table S1371. Gene #146: 'RGS3 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	169	120	221
RGS3 MUTATED	3	2	1
RGS3 WILD-TYPE	166	118	220

'RGS3 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.197 (Fisher's exact test), Q value = 0.84

Table S1372. Gene #146: 'RGS3 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	222	81	168	42
RGS3 MUTATED	4	2	0	0
RGS3 WILD-TYPE	218	79	168	42

'RGS3 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.626 (Fisher's exact test), Q value = 1

Table S1373. Gene #146: 'RGS3 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	52	62	68	74
RGS3 MUTATED	0	0	1	2
RGS3 WILD-TYPE	52	62	67	72

'RGS3 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.194 (Fisher's exact test), Q value = 0.84

Table S1374. Gene #146: 'RGS3 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	67	131	58
RGS3 MUTATED	0	1	2
RGS3 WILD-TYPE	67	130	56

'RGS3 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.556 (Fisher's exact test), Q value = 1

Table S1375. Gene #146: 'RGS3 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	132	109	109	133	30
RGS3 MUTATED	1	2	0	3	0
RGS3 WILD-TYPE	131	107	109	130	30

'RGS3 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0242 (Fisher's exact test), Q value = 0.25

Table S1376. Gene #146: 'RGS3 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	134	71	36	66	91	41	74
RGS3 MUTATED	1	0	0	3	0	2	0
RGS3 WILD-TYPE	133	71	36	63	91	39	74

Figure S213. Get High-res Image Gene #146: 'RGS3 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'RGS3 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.215 (Fisher's exact test), Q value = 0.86

Table S1377. Gene #146: 'RGS3 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
RGS3 MUTATED	0	2	4	0
RGS3 WILD-TYPE	136	105	179	83

'RGS3 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.755 (Fisher's exact test), Q value = 1

Table S1378. Gene #146: 'RGS3 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
RGS3 MUTATED	2	2	2
RGS3 WILD-TYPE	220	182	101

'RGS3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.293 (Fisher's exact test), Q value = 0.92

Table S1379. Gene #146: 'RGS3 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
RGS3 MUTATED	1	1	4
RGS3 WILD-TYPE	183	161	155

'RGS3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.94 (Fisher's exact test), Q value = 1

Table S1380. Gene #146: 'RGS3 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
RGS3 MUTATED	1	1	3	1
RGS3 WILD-TYPE	89	137	185	88

Methods & Data

Input

Mutation data file = sample_sig_gene_table.txt from Mutsig_2CV pipeline
Processed Mutation data file = /xchip/cga/gdac-prod/tcga-gdac/jobResults/GDAC_Correlate_Genomic_Events_Preprocess/LGG-TP/15716583/transformed.cor.cli.txt
Molecular subtypes file = /xchip/cga/gdac-prod/tcga-gdac/jobResults/GDAC_mergedClustering/LGG-TP/15115118/LGG-TP.transferedmergedcluster.txt
Number of patients = 513
Number of significantly mutated genes = 146
Number of Molecular subtypes = 12
Exclude genes that fewer than K tumors have mutations, K = 3

Fisher's exact test

For binary or multi-class clinical features (nominal or ordinal), two-tailed Fisher's exact tests (Fisher 1922) were used to estimate the P values using the 'fisher.test' function in R

Q value calculation

For multiple hypothesis correction, Q value is the False Discovery Rate (FDR) analogue of the P value (Benjamini and Hochberg 1995), defined as the minimum FDR at which the test may be called significant. We used the 'Benjamini and Hochberg' method of 'p.adjust' function in R to convert P values into Q values.

Download Results

In addition to the links below, the full results of the analysis summarized in this report can also be downloaded programmatically using firehose_get, or interactively from either the Broad GDAC website or TCGA Data Coordination Center Portal.

References

[1] Fisher, R.A., On the interpretation of chi-square from contingency tables, and the calculation of P, Journal of the Royal Statistical Society 85(1):87-94 (1922)

[2] Benjamini and Hochberg, Controlling the false discovery rate: a practical and powerful approach to multiple testing, Journal of the Royal Statistical Society Series B 59:289-300 (1995)

Made with Nozzle