Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.063 0.149 0.4 81.0 -9999.0 0.0 81.0 KIRREL -0.037 0.164 -9999.0 0.0 -0.594 41.0 41.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.063 0.15 -9999.0 0.0 -0.4 81.0 81.0 PLCG1 0.014 0.0 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.014 0.0 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.014 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.046 0.108 -9999.0 0.0 -0.337 42.0 42.0 ChemicalAbstracts:57-88-5 -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.004 0.096 -9999.0 0.0 -0.417 6.0 6.0 FYN -0.024 0.109 -9999.0 0.0 -0.321 42.0 42.0 mol:Ca2+ -0.045 0.108 -9999.0 0.0 -0.337 38.0 38.0 mol:DAG -0.045 0.108 -9999.0 0.0 -0.339 38.0 38.0 NPHS2 -0.006 0.039 -9999.0 0.0 -0.537 2.0 2.0 mol:IP3 -0.045 0.108 -9999.0 0.0 -0.339 38.0 38.0 regulation of endocytosis -0.015 0.103 -9999.0 0.0 -0.359 11.0 11.0 Nephrin/NEPH1/podocin/Cholesterol -0.047 0.112 -9999.0 0.0 -0.346 42.0 42.0 establishment of cell polarity -0.063 0.149 -9999.0 0.0 -0.4 81.0 81.0 Nephrin/NEPH1/podocin/NCK1-2 -0.041 0.099 -9999.0 0.0 -0.533 5.0 5.0 Nephrin/NEPH1/beta Arrestin2 -0.014 0.104 -9999.0 0.0 -0.363 11.0 11.0 NPHS1 -0.035 0.141 -9999.0 0.0 -0.494 44.0 44.0 Nephrin/NEPH1/podocin -0.027 0.109 -9999.0 0.0 -0.323 42.0 42.0 TJP1 0.014 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.013 0.027 -9999.0 0.0 -0.593 1.0 1.0 NCK2 0.014 0.0 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.046 0.108 -9999.0 0.0 -0.34 38.0 38.0 CD2AP 0.014 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 -0.046 0.109 -9999.0 0.0 -0.337 42.0 42.0 GRB2 0.013 0.022 -9999.0 0.0 -0.489 1.0 1.0 homophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.043 0.134 -9999.0 0.0 -0.342 51.0 51.0 cytoskeleton organization -0.004 0.111 -9999.0 0.0 -0.457 7.0 7.0 Nephrin/NEPH1 -0.045 0.107 -9999.0 0.0 -0.333 41.0 41.0 Nephrin/NEPH1/ZO-1 -0.049 0.117 -9999.0 0.0 -0.365 41.0 41.0