Signaling events mediated by the Hedgehog family
Entity	Mean	Std Dev	Mean of Up Perturbations	Number of Up Perturbations	Mean of Down Perturbations	Number of Down Perturbations	Number of Total Perturbations
TGFB2	-0.092	0.184	0.263	39.0	-0.497	47.0	86.0
IHH	-0.015	0.127	0.274	7.0	-0.374	47.0	54.0
SHH Np/Cholesterol/GAS1	-0.036	0.058	0.115	1.0	-0.183	65.0	66.0
LRPAP1	0.021	0.004	-9999.0	0.0	-9999.0	0.0	0.0
dorsoventral neural tube patterning	0.036	0.058	0.183	65.0	-0.113	1.0	66.0
SMO/beta Arrestin2	-0.148	0.183	0.301	2.0	-0.325	213.0	215.0
SMO	-0.15	0.187	0.282	2.0	-0.338	211.0	213.0
AKT1	-0.081	0.142	0.266	1.0	-0.474	36.0	37.0
ARRB2	0.02	0.006	-9999.0	0.0	-9999.0	0.0	0.0
BOC	0.02	0.016	-9999.0	0.0	-0.325	1.0	1.0
ADRBK1	0.021	0.004	-9999.0	0.0	-9999.0	0.0	0.0
heart looping	-0.149	0.185	0.281	2.0	-0.331	218.0	220.0
STIL	-0.088	0.142	0.214	22.0	-0.319	69.0	91.0
DHH N/PTCH2	0.013	0.066	-9999.0	0.0	-0.228	36.0	36.0
DHH N/PTCH1	-0.109	0.154	-9999.0	0.0	-0.238	252.0	252.0
PIK3CA	0.02	0.004	-9999.0	0.0	-9999.0	0.0	0.0
DHH	-0.003	0.088	-9999.0	0.0	-0.325	36.0	36.0
PTHLH	-0.125	0.224	0.383	7.0	-0.557	45.0	52.0
determination of left/right symmetry	-0.149	0.185	0.281	2.0	-0.331	218.0	220.0
PIK3R1	0.02	0.016	-9999.0	0.0	-0.325	1.0	1.0
skeletal system development	-0.124	0.223	0.382	7.0	-0.553	45.0	52.0
IHH N/Hhip	-0.22	0.18	0.208	3.0	-0.318	371.0	374.0
DHH N/Hhip	-0.12	0.141	-9999.0	0.0	-0.244	280.0	280.0
mol:Cholesterol	-0.0	0.0	-9999.0	0.0	-9999.0	0.0	0.0
heart development	-0.149	0.185	0.281	2.0	-0.331	218.0	220.0
pancreas development	-0.163	0.172	-9999.0	0.0	-0.324	273.0	273.0
HHAT	0.018	0.022	-9999.0	0.0	-0.325	2.0	2.0
PI3K	0.029	0.014	-9999.0	0.0	-0.229	1.0	1.0
EntrezGene:84976	0.0	0.0	-9999.0	0.0	-9999.0	0.0	0.0
GAS1	0.012	0.054	-9999.0	0.0	-0.325	13.0	13.0
somite specification	-0.149	0.185	0.281	2.0	-0.331	218.0	220.0
SHH Np/Cholesterol/PTCH1	-0.099	0.14	0.176	1.0	-0.337	72.0	73.0
SHH Np/Cholesterol/PTCH2	-0.034	0.052	0.115	1.0	-0.175	60.0	61.0
SHH Np/Cholesterol/Megalin	-0.069	0.087	0.115	1.0	-0.191	159.0	160.0
SHH	-0.039	0.07	0.155	1.0	-0.229	60.0	61.0
catabolic process	-0.11	0.162	0.233	3.0	-0.253	249.0	252.0
SMO/Vitamin D3	-0.125	0.172	0.37	2.0	-0.291	220.0	222.0
SHH Np/Cholesterol/Hhip	-0.104	0.101	0.115	1.0	-0.198	251.0	252.0
LRP2	-0.072	0.155	0.324	1.0	-0.325	139.0	140.0
receptor-mediated endocytosis	-0.17	0.185	0.303	2.0	-0.398	146.0	148.0
SHH Np/Cholesterol/BOC	-0.033	0.052	0.115	1.0	-0.175	59.0	60.0
SHH Np/Cholesterol/CDO	-0.035	0.056	0.115	1.0	-0.178	64.0	65.0
mesenchymal cell differentiation	0.103	0.1	0.197	251.0	-0.113	1.0	252.0
mol:Vitamin D3	-0.093	0.153	0.332	7.0	-0.338	72.0	79.0
IHH N/PTCH2	-0.097	0.128	0.208	4.0	-0.21	279.0	283.0
CDON	0.013	0.048	-9999.0	0.0	-0.325	10.0	10.0
IHH N/PTCH1	-0.102	0.174	0.234	39.0	-0.254	256.0	295.0
Megalin/LRPAP1	-0.038	0.115	0.234	1.0	-0.228	136.0	137.0
PTCH2	0.02	0.015	-9999.0	0.0	-0.325	1.0	1.0
SHH Np/Cholesterol	-0.029	0.052	-9999.0	0.0	-0.17	60.0	60.0
PTCH1	-0.11	0.163	0.233	3.0	-0.254	249.0	252.0
HHIP	-0.164	0.172	-9999.0	0.0	-0.325	273.0	273.0