Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.242 0.282 0.513 42.0 -9999.0 0.0 42.0 KIRREL -0.086 0.217 -9999.0 0.0 -0.68 10.0 10.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.243 0.283 -9999.0 0.0 -0.514 42.0 42.0 PLCG1 0.014 0.0 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.014 0.0 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.014 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.193 0.216 -9999.0 0.0 -0.429 32.0 32.0 ChemicalAbstracts:57-88-5 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.134 0.201 -9999.0 0.0 -0.356 32.0 32.0 FYN -0.178 0.22 -9999.0 0.0 -0.406 34.0 34.0 mol:Ca2+ -0.191 0.213 -9999.0 0.0 -0.425 32.0 32.0 mol:DAG -0.192 0.215 -9999.0 0.0 -0.427 32.0 32.0 NPHS2 -0.04 0.092 -9999.0 0.0 -0.601 2.0 2.0 mol:IP3 -0.192 0.215 -9999.0 0.0 -0.427 32.0 32.0 regulation of endocytosis -0.16 0.209 -9999.0 0.0 -0.566 9.0 9.0 Nephrin/NEPH1/podocin/Cholesterol -0.197 0.219 -9999.0 0.0 -0.4 42.0 42.0 establishment of cell polarity -0.242 0.282 -9999.0 0.0 -0.513 42.0 42.0 Nephrin/NEPH1/podocin/NCK1-2 -0.177 0.21 -9999.0 0.0 -0.643 8.0 8.0 Nephrin/NEPH1/beta Arrestin2 -0.162 0.213 -9999.0 0.0 -0.576 9.0 9.0 NPHS1 -0.273 0.316 -9999.0 0.0 -0.626 38.0 38.0 Nephrin/NEPH1/podocin -0.179 0.222 -9999.0 0.0 -0.409 34.0 34.0 TJP1 0.006 0.071 -9999.0 0.0 -0.653 1.0 1.0 NCK1 0.014 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.006 0.071 -9999.0 0.0 -0.653 1.0 1.0 heterophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.193 0.216 -9999.0 0.0 -0.429 32.0 32.0 CD2AP 0.014 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 -0.193 0.216 -9999.0 0.0 -0.429 32.0 32.0 GRB2 0.014 0.0 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.199 0.233 -9999.0 0.0 -0.416 38.0 38.0 cytoskeleton organization -0.164 0.237 -9999.0 0.0 -0.442 30.0 30.0 Nephrin/NEPH1 -0.177 0.213 -9999.0 0.0 -0.376 42.0 42.0 Nephrin/NEPH1/ZO-1 -0.206 0.238 -9999.0 0.0 -0.433 38.0 38.0