Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.131 0.206 0.345 37.0 -9999.0 0.0 37.0 KIRREL -0.054 0.165 -9999.0 0.0 -0.525 9.0 9.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.132 0.207 -9999.0 0.0 -0.346 37.0 37.0 PLCG1 0.029 0.0 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.027 0.006 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.026 0.008 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.083 0.171 -9999.0 0.0 -0.306 28.0 28.0 ChemicalAbstracts:57-88-5 -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.082 0.156 -9999.0 0.0 -0.297 25.0 25.0 FYN -0.087 0.17 0.27 4.0 -0.291 29.0 33.0 mol:Ca2+ -0.085 0.17 -9999.0 0.0 -0.302 29.0 29.0 mol:DAG -0.085 0.171 -9999.0 0.0 -0.303 29.0 29.0 NPHS2 -0.022 0.056 -9999.0 0.0 -0.269 2.0 2.0 mol:IP3 -0.085 0.171 -9999.0 0.0 -0.303 29.0 29.0 regulation of endocytosis -0.078 0.156 -9999.0 0.0 -0.283 27.0 27.0 Nephrin/NEPH1/podocin/Cholesterol -0.093 0.164 -9999.0 0.0 -0.303 29.0 29.0 establishment of cell polarity -0.131 0.206 -9999.0 0.0 -0.345 37.0 37.0 Nephrin/NEPH1/podocin/NCK1-2 -0.072 0.175 -9999.0 0.0 -0.295 27.0 27.0 Nephrin/NEPH1/beta Arrestin2 -0.078 0.159 -9999.0 0.0 -0.286 27.0 27.0 NPHS1 -0.157 0.23 -9999.0 0.0 -0.412 36.0 36.0 Nephrin/NEPH1/podocin -0.09 0.16 -9999.0 0.0 -0.292 29.0 29.0 TJP1 0.02 0.057 -9999.0 0.0 -0.496 1.0 1.0 NCK1 0.029 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.022 0.056 -9999.0 0.0 -0.496 1.0 1.0 heterophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.085 0.173 -9999.0 0.0 -0.305 29.0 29.0 CD2AP 0.028 0.005 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 -0.089 0.169 -9999.0 0.0 -0.305 29.0 29.0 GRB2 0.027 0.007 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.096 0.176 0.279 4.0 -0.296 30.0 34.0 cytoskeleton organization -0.103 0.185 0.204 4.0 -0.357 25.0 29.0 Nephrin/NEPH1 -0.089 0.15 -9999.0 0.0 -0.291 27.0 27.0 Nephrin/NEPH1/ZO-1 -0.099 0.184 -9999.0 0.0 -0.339 27.0 27.0