Clinical Features MRNA_CNMF MRNA_CHIERARCHICAL MIR_CNMF MIR_CHIERARCHICAL CN_CNMF METHLYATION_CNMF RPPA_CNMF RPPA_CHIERARCHICAL MRNASEQ_CNMF MRNASEQ_CHIERARCHICAL MIRSEQ_CNMF MIRSEQ_CHIERARCHICAL MIRSEQ_MATURE_CNMF MIRSEQ_MATURE_CHIERARCHICAL nMutated (%) nWild-Type Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q TP53 383 (82%) 83 0.97512 1 0.19989 1 0.8525 1 0.42641 1 0.42084 1 0.1607 1 0.13971 1 0.42251 1 0.35312 1 0.892 1 0.9348 1 0.88537 1 1 1 NA NA BRCA1 19 (4%) 447 0.079639 1 0.41348 1 0.58309 1 0.97904 1 0.02642 0.931 0.04011 0.931 0.37883 1 0.36909 1 0.45472 1 0.59091 1 0.069209 1 0.13145 1 NA NA NA NA NF1 24 (5%) 442 0.62199 1 0.54035 1 0.72341 1 0.72885 1 0.37848 1 0.03421 0.931 0.13011 1 0.094699 1 0.37735 1 0.13698 1 0.59154 1 0.23278 1 0.35714 1 NA NA RB1 15 (3%) 451 0.097129 1 0.28466 1 0.68159 1 0.93122 1 0.11895 1 0.01557 0.931 0.77352 1 0.75914 1 0.11441 1 0.54254 1 0.51161 1 0.26936 1 NA NA NA NA BRCA2 13 (3%) 453 0.93635 1 0.53103 1 1 1 0.64816 1 0.35733 1 0.30554 1 0.4893 1 0.68207 1 0.55456 1 0.5634 1 0.81744 1 0.57647 1 0.35714 1 NA NA IL21R 8 (2%) 458 0.04478 0.961 0.14711 1 0.24595 1 0.01842 0.931 0.12893 1 0.14952 1 0.29499 1 0.91945 1 0.089399 1 0.075349 1 0.73364 1 0.55517 1 NA NA NA NA KRAS 5 (1%) 461 0.25826 1 0.35808 1 0.088619 1 0.39382 1 0.04048 0.931 0.74015 1 0.091009 1 0.74887 1 0.11924 1 0.18829 1 0.34793 1 0.52324 1 NA NA NA NA YSK4 10 (2%) 456 1 1 0.59733 1 1 1 0.39619 1 0.83864 1 0.19561 1 0.47741 1 0.053739 1 0.55453 1 0.41096 1 0.54414 1 0.83297 1 NA NA NA NA ANKRD35 9 (2%) 457 0.43482 1 0.64718 1 0.15626 1 0.34217 1 0.33731 1 0.40533 1 0.86258 1 0.53255 1 0.78933 1 0.74737 1 0.62503 1 0.36678 1 NA NA NA NA C9ORF171 5 (1%) 461 0.00070999 0.229 0.00403 0.649 0.39557 1 0.25455 1 0.86605 1 0.01387 0.931 0.19606 1 0.68328 1 NA NA NA NA 0.29983 1 0.49594 1 NA NA NA NA MTA2 4 (1%) 462 0.45752 1 0.3695 1 0.30863 1 0.84046 1 0.4024 1 0.47536 1 0.684 1 0.91293 1 NA NA NA NA NA NA NA NA 1 1 NA NA CYP11B1 8 (2%) 458 0.10541 1 0.69989 1 0.49774 1 0.03517 0.931 0.2967 1 0.15016 1 0.064819 1 0.24734 1 0.44231 1 1 1 0.12262 1 0.64933 1 NA NA NA NA NRAS 4 (1%) 462 0.83996 1 0.36916 1 0.57021 1 0.20214 1 0.46877 1 0.56461 1 1 1 0.52995 1 NA NA NA NA 0.6176 1 0.23345 1 NA NA NA NA ACBD4 3 (1%) 463 0.46837 1 0.02303 0.931 0.48276 1 0.15264 1 1 1 0.3828 1 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA EFEMP1 7 (2%) 459 1 1 1 1 0.12066 1 0.7482 1 0.2071 1 0.03418 0.931 0.71496 1 1 1 NA NA NA NA 0.71066 1 0.47633 1 NA NA NA NA PODN 6 (1%) 460 0.51561 1 0.23812 1 0.77613 1 0.15719 1 0.291 1 0.25977 1 0.11107 1 0.22895 1 NA NA NA NA 0.48225 1 0.39182 1 NA NA NA NA TOP2A 8 (2%) 458 0.35411 1 0.69874 1 0.67076 1 0.28745 1 0.80037 1 0.01999 0.931 0.79025 1 1 1 NA NA NA NA 0.79806 1 0.68461 1 NA NA NA NA NCOA3 5 (1%) 461 0.095759 1 0.22353 1 0.73808 1 0.64309 1 0.86291 1 0.52854 1 NA NA NA NA NA NA NA NA 0.1764 1 0.22869 1 NA NA NA NA TP53TG5 3 (1%) 463 0.46426 1 0.5565 1 0.48402 1 0.25108 1 0.063879 1 0.19791 1 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA RPGRIP1 7 (2%) 459 1 1 0.76708 1 0.03494 0.931 0.56503 1 0.89676 1 0.34808 1 0.48904 1 0.61631 1 0.55459 1 1 1 0.71144 1 0.58395 1 NA NA NA NA PTEN 5 (1%) 461 0.64997 1 0.55745 1 0.19291 1 0.14231 1 0.28094 1 0.73869 1 1 1 0.119 1 NA NA NA NA 0.68541 1 0.82786 1 NA NA NA NA RB1CC1 9 (2%) 457 0.75888 1 0.41458 1 0.2936 1 0.6472 1 0.70243 1 0.40305 1 1 1 0.20667 1 0.78785 1 0.49753 1 0.4296 1 0.28199 1 NA NA NA NA LPAR3 4 (1%) 462 0.68141 1 0.36611 1 0.30957 1 0.32433 1 0.83895 1 0.073279 1 0.81579 1 0.21669 1 0.47206 1 0.7469 1 0.61612 1 0.6879 1 NA NA NA NA