Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.079 0.171 0.458 33.0 -9999.0 0.0 33.0 KIRREL -0.003 0.043 -9999.0 0.0 -0.44 2.0 2.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.08 0.171 -9999.0 0.0 -0.459 33.0 33.0 PLCG1 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.052 0.134 -9999.0 0.0 -0.363 32.0 32.0 ChemicalAbstracts:57-88-5 -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.029 0.106 -9999.0 0.0 -0.304 25.0 25.0 FYN -0.055 0.128 -9999.0 0.0 -0.346 34.0 34.0 mol:Ca2+ -0.065 0.126 -9999.0 0.0 -0.36 32.0 32.0 mol:DAG -0.052 0.133 -9999.0 0.0 -0.362 32.0 32.0 NPHS2 -0.018 0.07 -9999.0 0.0 -0.419 7.0 7.0 mol:IP3 -0.052 0.133 -9999.0 0.0 -0.362 32.0 32.0 regulation of endocytosis -0.045 0.122 -9999.0 0.0 -0.322 33.0 33.0 Nephrin/NEPH1/podocin/Cholesterol -0.06 0.133 -9999.0 0.0 -0.37 32.0 32.0 establishment of cell polarity -0.079 0.171 -9999.0 0.0 -0.458 33.0 33.0 Nephrin/NEPH1/podocin/NCK1-2 -0.04 0.123 -9999.0 0.0 -0.329 28.0 28.0 Nephrin/NEPH1/beta Arrestin2 -0.044 0.123 -9999.0 0.0 -0.326 33.0 33.0 NPHS1 -0.116 0.226 -9999.0 0.0 -0.498 64.0 64.0 Nephrin/NEPH1/podocin -0.055 0.129 -9999.0 0.0 -0.348 34.0 34.0 TJP1 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.052 0.134 -9999.0 0.0 -0.363 32.0 32.0 CD2AP 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 -0.052 0.134 -9999.0 0.0 -0.363 32.0 32.0 GRB2 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.056 0.129 -9999.0 0.0 -0.334 37.0 37.0 cytoskeleton organization -0.037 0.132 -9999.0 0.0 -0.379 27.0 27.0 Nephrin/NEPH1 -0.054 0.122 -9999.0 0.0 -0.35 28.0 28.0 Nephrin/NEPH1/ZO-1 -0.054 0.138 -9999.0 0.0 -0.391 27.0 27.0