Signaling events mediated by the Hedgehog family
Entity	Mean	Std Dev	Mean of Up Perturbations	Number of Up Perturbations	Mean of Down Perturbations	Number of Down Perturbations	Number of Total Perturbations
TGFB2	-0.031	0.111	0.493	12.0	-0.452	15.0	27.0
IHH	-0.005	0.077	0.157	88.0	-9999.0	0.0	88.0
SHH Np/Cholesterol/GAS1	-0.045	0.037	0.142	1.0	-0.131	77.0	78.0
LRPAP1	0.028	0.007	-9999.0	0.0	0.0	33.0	33.0
dorsoventral neural tube patterning	0.044	0.037	0.131	77.0	-0.14	1.0	78.0
SMO/beta Arrestin2	0.026	0.132	0.293	84.0	-0.388	9.0	93.0
SMO	0.028	0.132	0.302	84.0	-0.398	9.0	93.0
AKT1	-0.024	0.147	0.324	2.0	-0.449	18.0	20.0
ARRB2	0.028	0.006	-9999.0	0.0	0.0	25.0	25.0
BOC	0.026	0.01	-9999.0	0.0	0.0	80.0	80.0
ADRBK1	0.029	0.003	-9999.0	0.0	0.0	6.0	6.0
heart looping	0.028	0.132	0.301	84.0	-0.393	9.0	93.0
STIL	0.001	0.064	0.27	20.0	-9999.0	0.0	20.0
DHH N/PTCH2	0.042	0.009	-9999.0	0.0	-9999.0	0.0	0.0
DHH N/PTCH1	0.006	0.132	0.31	79.0	-0.281	10.0	89.0
PIK3CA	0.021	0.014	-9999.0	0.0	0.0	174.0	174.0
DHH	0.03	0.003	-9999.0	0.0	0.0	4.0	4.0
PTHLH	0.032	0.19	0.486	71.0	-0.441	1.0	72.0
determination of left/right symmetry	0.028	0.132	0.301	84.0	-0.393	9.0	93.0
PIK3R1	0.021	0.013	-9999.0	0.0	0.0	159.0	159.0
skeletal system development	0.032	0.19	0.485	71.0	-0.438	1.0	72.0
IHH N/Hhip	0.049	0.041	0.179	3.0	-9999.0	0.0	3.0
DHH N/Hhip	0.042	0.01	-9999.0	0.0	-9999.0	0.0	0.0
mol:Cholesterol	0.0	0.0	-9999.0	0.0	-9999.0	0.0	0.0
heart development	0.028	0.132	0.301	84.0	-0.393	9.0	93.0
pancreas development	0.028	0.006	-9999.0	0.0	0.0	26.0	26.0
HHAT	0.029	0.006	-9999.0	0.0	0.0	20.0	20.0
PI3K	-0.001	0.068	-9999.0	0.0	-0.164	77.0	77.0
EntrezGene:84976	-0.0	0.0	-9999.0	0.0	-9999.0	0.0	0.0
GAS1	0.025	0.011	-9999.0	0.0	0.0	94.0	94.0
somite specification	0.028	0.132	0.301	84.0	-0.393	9.0	93.0
SHH Np/Cholesterol/PTCH1	-0.003	0.114	0.265	75.0	-0.268	8.0	83.0
SHH Np/Cholesterol/PTCH2	-0.032	0.016	0.142	1.0	-0.13	5.0	6.0
SHH Np/Cholesterol/Megalin	-0.025	0.019	-9999.0	0.0	-0.13	4.0	4.0
SHH	-0.03	0.014	0.19	1.0	-9999.0	0.0	1.0
catabolic process	0.022	0.156	0.372	84.0	-0.319	8.0	92.0
SMO/Vitamin D3	0.004	0.121	0.256	76.0	-0.364	9.0	85.0
SHH Np/Cholesterol/Hhip	-0.031	0.016	0.142	1.0	-0.13	5.0	6.0
LRP2	0.022	0.013	-9999.0	0.0	0.0	140.0	140.0
receptor-mediated endocytosis	0.026	0.125	0.277	75.0	-0.403	8.0	83.0
SHH Np/Cholesterol/BOC	-0.04	0.033	0.142	1.0	-0.13	55.0	56.0
SHH Np/Cholesterol/CDO	-0.032	0.018	0.142	1.0	-0.13	7.0	8.0
mesenchymal cell differentiation	0.031	0.016	0.13	5.0	-0.14	1.0	6.0
mol:Vitamin D3	0.004	0.117	0.257	75.0	-0.268	8.0	83.0
IHH N/PTCH2	0.05	0.041	0.179	4.0	-9999.0	0.0	4.0
CDON	0.028	0.007	-9999.0	0.0	0.0	32.0	32.0
IHH N/PTCH1	-0.034	0.054	-9999.0	0.0	-0.277	24.0	24.0
Megalin/LRPAP1	0.031	0.023	-9999.0	0.0	-0.164	2.0	2.0
PTCH2	0.029	0.006	-9999.0	0.0	0.0	20.0	20.0
SHH Np/Cholesterol	-0.022	0.014	0.155	1.0	-0.119	5.0	6.0
PTCH1	0.022	0.157	0.373	84.0	-0.32	8.0	92.0
HHIP	0.028	0.006	-9999.0	0.0	0.0	26.0	26.0