Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.078 0.162 0.286 63.0 -9999.0 0.0 63.0 KIRREL -0.022 0.11 -9999.0 0.0 -0.388 13.0 13.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.078 0.162 -9999.0 0.0 -0.286 63.0 63.0 PLCG1 0.036 0.009 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.031 0.033 -9999.0 0.0 -0.372 1.0 1.0 WASL 0.036 0.008 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.046 0.146 -9999.0 0.0 -0.217 69.0 69.0 ChemicalAbstracts:57-88-5 -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.07 0.136 -9999.0 0.0 -0.237 64.0 64.0 FYN -0.055 0.128 0.264 3.0 -0.21 64.0 67.0 mol:Ca2+ -0.043 0.144 -9999.0 0.0 -0.216 67.0 67.0 mol:DAG -0.042 0.145 -9999.0 0.0 -0.216 67.0 67.0 NPHS2 -0.027 0.104 -9999.0 0.0 -0.385 12.0 12.0 mol:IP3 -0.042 0.145 -9999.0 0.0 -0.216 67.0 67.0 regulation of endocytosis -0.043 0.128 -9999.0 0.0 -0.201 60.0 60.0 Nephrin/NEPH1/podocin/Cholesterol -0.054 0.137 -9999.0 0.0 -0.214 70.0 70.0 establishment of cell polarity -0.078 0.162 -9999.0 0.0 -0.286 63.0 63.0 Nephrin/NEPH1/podocin/NCK1-2 -0.027 0.145 -9999.0 0.0 -0.341 8.0 8.0 Nephrin/NEPH1/beta Arrestin2 -0.042 0.13 -9999.0 0.0 -0.203 60.0 60.0 NPHS1 -0.107 0.191 -9999.0 0.0 -0.381 57.0 57.0 Nephrin/NEPH1/podocin -0.051 0.133 -9999.0 0.0 -0.208 69.0 69.0 TJP1 0.037 0.007 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.037 0.006 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.038 0.005 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.042 0.146 -9999.0 0.0 -0.217 67.0 67.0 CD2AP 0.037 0.007 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 -0.045 0.143 -9999.0 0.0 -0.216 65.0 65.0 GRB2 0.035 0.011 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.059 0.123 0.284 3.0 -0.204 62.0 65.0 cytoskeleton organization -0.092 0.149 -9999.0 0.0 -0.277 64.0 64.0 Nephrin/NEPH1 -0.048 0.115 -9999.0 0.0 -0.195 63.0 63.0 Nephrin/NEPH1/ZO-1 -0.045 0.14 -9999.0 0.0 -0.223 63.0 63.0