Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.067 0.152 0.346 112.0 -9999.0 0.0 112.0 KIRREL -0.087 0.196 -9999.0 0.0 -0.472 102.0 102.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.067 0.152 -9999.0 0.0 -0.347 112.0 112.0 PLCG1 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.039 0.115 -9999.0 0.0 -0.321 16.0 16.0 ChemicalAbstracts:57-88-5 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.029 0.105 -9999.0 0.0 -0.356 5.0 5.0 FYN -0.042 0.11 -9999.0 0.0 -0.309 16.0 16.0 mol:Ca2+ -0.04 0.114 -9999.0 0.0 -0.321 15.0 15.0 mol:DAG -0.039 0.115 -9999.0 0.0 -0.323 15.0 15.0 NPHS2 -0.011 0.049 -9999.0 0.0 -0.584 3.0 3.0 mol:IP3 -0.039 0.115 -9999.0 0.0 -0.323 15.0 15.0 regulation of endocytosis -0.031 0.104 -9999.0 0.0 -0.442 4.0 4.0 Nephrin/NEPH1/podocin/Cholesterol -0.048 0.115 -9999.0 0.0 -0.254 114.0 114.0 establishment of cell polarity -0.067 0.152 -9999.0 0.0 -0.346 112.0 112.0 Nephrin/NEPH1/podocin/NCK1-2 -0.028 0.108 -9999.0 0.0 -0.5 3.0 3.0 Nephrin/NEPH1/beta Arrestin2 -0.031 0.106 -9999.0 0.0 -0.448 4.0 4.0 NPHS1 -0.015 0.086 -9999.0 0.0 -0.572 11.0 11.0 Nephrin/NEPH1/podocin -0.042 0.11 -9999.0 0.0 -0.31 16.0 16.0 TJP1 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.012 0.026 -9999.0 0.0 -0.573 1.0 1.0 NCK2 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.039 0.115 -9999.0 0.0 -0.324 15.0 15.0 CD2AP 0.013 0.001 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 -0.039 0.115 -9999.0 0.0 -0.321 16.0 16.0 GRB2 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.079 0.158 -9999.0 0.0 -0.411 60.0 60.0 cytoskeleton organization -0.029 0.115 -9999.0 0.0 -0.392 5.0 5.0 Nephrin/NEPH1 -0.045 0.106 -9999.0 0.0 -0.24 112.0 112.0 Nephrin/NEPH1/ZO-1 -0.043 0.121 -9999.0 0.0 -0.266 110.0 110.0