Signaling events mediated by the Hedgehog family
Entity	Mean	Std Dev	Mean of Up Perturbations	Number of Up Perturbations	Mean of Down Perturbations	Number of Down Perturbations	Number of Total Perturbations
TGFB2	-0.039	0.168	0.392	1.0	-0.575	5.0	6.0
IHH	-0.093	0.245	0.245	1.0	-0.583	50.0	51.0
SHH Np/Cholesterol/GAS1	-0.055	0.111	0.159	1.0	-0.32	37.0	38.0
LRPAP1	0.019	0.004	-9999.0	0.0	-9999.0	0.0	0.0
dorsoventral neural tube patterning	0.055	0.11	0.318	37.0	-0.157	1.0	38.0
SMO/beta Arrestin2	-0.078	0.196	0.318	1.0	-0.421	50.0	51.0
SMO	-0.088	0.196	-9999.0	0.0	-0.436	51.0	51.0
AKT1	-0.035	0.12	-9999.0	0.0	-0.515	6.0	6.0
ARRB2	0.018	0.005	-9999.0	0.0	-9999.0	0.0	0.0
BOC	0.019	0.06	0.255	5.0	-0.549	2.0	7.0
ADRBK1	0.019	0.003	-9999.0	0.0	-9999.0	0.0	0.0
heart looping	-0.088	0.195	-9999.0	0.0	-0.429	52.0	52.0
STIL	-0.063	0.168	0.287	7.0	-0.481	11.0	18.0
DHH N/PTCH2	0.014	0.1	0.191	11.0	-0.407	12.0	23.0
DHH N/PTCH1	-0.048	0.17	0.333	1.0	-0.33	59.0	60.0
PIK3CA	0.019	0.003	-9999.0	0.0	-9999.0	0.0	0.0
DHH	-0.003	0.12	0.255	4.0	-0.549	11.0	15.0
PTHLH	-0.07	0.231	0.483	1.0	-1.05	5.0	6.0
determination of left/right symmetry	-0.088	0.195	-9999.0	0.0	-0.429	52.0	52.0
PIK3R1	0.02	0.015	0.255	1.0	-9999.0	0.0	1.0
skeletal system development	-0.069	0.228	0.482	1.0	-1.033	5.0	6.0
IHH N/Hhip	-0.115	0.239	0.249	8.0	-0.436	84.0	92.0
DHH N/Hhip	-0.059	0.191	0.191	12.0	-0.415	54.0	66.0
mol:Cholesterol	0.0	0.0	-9999.0	0.0	-9999.0	0.0	0.0
heart development	-0.088	0.195	-9999.0	0.0	-0.429	52.0	52.0
pancreas development	-0.074	0.227	0.255	14.0	-0.548	45.0	59.0
HHAT	0.019	0.004	-9999.0	0.0	-9999.0	0.0	0.0
PI3K	0.028	0.017	-9999.0	0.0	-9999.0	0.0	0.0
EntrezGene:84976	0.0	0.0	-9999.0	0.0	-9999.0	0.0	0.0
GAS1	0.018	0.041	0.255	2.0	-0.549	1.0	3.0
somite specification	-0.088	0.195	-9999.0	0.0	-0.429	52.0	52.0
SHH Np/Cholesterol/PTCH1	-0.08	0.17	0.325	1.0	-0.316	75.0	76.0
SHH Np/Cholesterol/PTCH2	-0.05	0.118	0.172	9.0	-0.32	37.0	46.0
SHH Np/Cholesterol/Megalin	-0.194	0.181	-9999.0	0.0	-0.353	134.0	134.0
SHH	-0.069	0.138	-9999.0	0.0	-0.407	36.0	36.0
catabolic process	-0.045	0.168	0.287	9.0	-0.344	53.0	62.0
SMO/Vitamin D3	-0.101	0.192	0.385	2.0	-0.394	52.0	54.0
SHH Np/Cholesterol/Hhip	-0.099	0.171	0.169	12.0	-0.351	72.0	84.0
LRP2	-0.253	0.274	-9999.0	0.0	-0.549	117.0	117.0
receptor-mediated endocytosis	-0.211	0.216	0.279	1.0	-0.548	52.0	53.0
SHH Np/Cholesterol/BOC	-0.054	0.114	0.16	4.0	-0.318	38.0	42.0
SHH Np/Cholesterol/CDO	-0.053	0.111	0.16	3.0	-0.319	36.0	39.0
mesenchymal cell differentiation	0.099	0.169	0.349	72.0	-0.168	12.0	84.0
mol:Vitamin D3	-0.084	0.172	0.333	3.0	-0.321	69.0	72.0
IHH N/PTCH2	-0.043	0.17	0.24	9.0	-0.366	51.0	60.0
CDON	0.022	0.03	0.255	4.0	-9999.0	0.0	4.0
IHH N/PTCH1	-0.041	0.17	0.358	1.0	-0.348	53.0	54.0
Megalin/LRPAP1	-0.171	0.214	-9999.0	0.0	-0.406	114.0	114.0
PTCH2	0.026	0.059	0.255	10.0	-0.549	1.0	11.0
SHH Np/Cholesterol	-0.053	0.107	-9999.0	0.0	-0.316	36.0	36.0
PTCH1	-0.046	0.168	0.288	9.0	-0.345	53.0	62.0
HHIP	-0.074	0.228	0.255	14.0	-0.549	45.0	59.0