Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.023 0.1 0.221 48.0 -9999.0 0.0 48.0 KIRREL 0.001 0.053 -9999.0 0.0 -0.298 5.0 5.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.023 0.101 -9999.0 0.0 -0.221 48.0 48.0 PLCG1 0.023 0.01 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.026 0.007 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.026 0.006 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.02 0.122 -9999.0 0.0 -0.221 55.0 55.0 ChemicalAbstracts:57-88-5 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.033 0.095 -9999.0 0.0 -0.215 50.0 50.0 FYN -0.039 0.107 0.229 8.0 -0.211 54.0 62.0 mol:Ca2+ -0.021 0.115 -9999.0 0.0 -0.219 49.0 49.0 mol:DAG -0.021 0.115 -9999.0 0.0 -0.22 49.0 49.0 NPHS2 -0.059 0.157 -9999.0 0.0 -0.385 50.0 50.0 mol:IP3 -0.021 0.115 -9999.0 0.0 -0.22 49.0 49.0 regulation of endocytosis -0.022 0.106 -9999.0 0.0 -0.2 53.0 53.0 Nephrin/NEPH1/podocin/Cholesterol -0.031 0.115 -9999.0 0.0 -0.208 64.0 64.0 establishment of cell polarity -0.023 0.1 -9999.0 0.0 -0.221 48.0 48.0 Nephrin/NEPH1/podocin/NCK1-2 -0.009 0.119 -9999.0 0.0 -0.297 9.0 9.0 Nephrin/NEPH1/beta Arrestin2 -0.021 0.108 -9999.0 0.0 -0.202 53.0 53.0 NPHS1 -0.043 0.123 -9999.0 0.0 -0.296 49.0 49.0 Nephrin/NEPH1/podocin -0.027 0.11 -9999.0 0.0 -0.21 56.0 56.0 TJP1 0.027 0.004 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.027 0.004 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.027 0.003 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.02 0.116 -9999.0 0.0 -0.221 49.0 49.0 CD2AP 0.026 0.006 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 -0.021 0.123 -9999.0 0.0 -0.221 55.0 55.0 GRB2 0.027 0.004 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.044 0.103 0.198 9.0 -0.206 53.0 62.0 cytoskeleton organization -0.047 0.103 0.206 2.0 -0.239 50.0 52.0 Nephrin/NEPH1 -0.01 0.07 -9999.0 0.0 -0.147 48.0 48.0 Nephrin/NEPH1/ZO-1 -0.004 0.087 -9999.0 0.0 -0.221 15.0 15.0