Ras signaling in the CD4+ TCR pathway Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations ERK1-2/ELK1 0.023 0.123 -9999.0 0.0 -0.48 8.0 8.0 MAP3K8 0.026 0.006 -9999.0 0.0 -9999.0 0.0 0.0 FOS 0.013 0.102 0.244 1.0 -0.417 8.0 9.0 PRKCA 0.024 0.026 -9999.0 0.0 -0.375 1.0 1.0 PTPN7 0.02 0.04 -9999.0 0.0 -0.29 4.0 4.0 HRAS 0.026 0.006 -9999.0 0.0 -9999.0 0.0 0.0 PRKCB 0.003 0.092 -9999.0 0.0 -0.377 15.0 15.0 NRAS 0.026 0.005 -9999.0 0.0 -9999.0 0.0 0.0 RAS family/GTP 0.043 0.022 -9999.0 0.0 -9999.0 0.0 0.0 MAPK3 0.017 0.082 -9999.0 0.0 -0.483 5.0 5.0 MAP2K1 0.004 0.097 -9999.0 0.0 -0.351 14.0 14.0 ELK1 0.025 0.012 -9999.0 0.0 -9999.0 0.0 0.0 BRAF -0.001 0.085 -9999.0 0.0 -0.342 15.0 15.0 mol:GTP -0.0 0.001 -9999.0 0.0 -0.004 16.0 16.0 MAPK1 0.012 0.102 -9999.0 0.0 -0.498 8.0 8.0 RAF1 -0.002 0.087 -9999.0 0.0 -0.34 16.0 16.0 KRAS 0.024 0.009 -9999.0 0.0 -9999.0 0.0 0.0