Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.106 0.183 0.401 115.0 -9999.0 0.0 115.0 KIRREL -0.015 0.084 -9999.0 0.0 -0.65 7.0 7.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.106 0.183 -9999.0 0.0 -0.402 115.0 115.0 PLCG1 0.01 0.0 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.01 0.0 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.009 0.018 -9999.0 0.0 -0.373 1.0 1.0 Nephrin/NEPH1/podocin/CD2AP -0.112 0.168 -9999.0 0.0 -0.388 108.0 108.0 ChemicalAbstracts:57-88-5 -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.069 0.151 -9999.0 0.0 -0.327 105.0 105.0 FYN -0.093 0.168 -9999.0 0.0 -0.369 108.0 108.0 mol:Ca2+ -0.111 0.166 -9999.0 0.0 -0.385 108.0 108.0 mol:DAG -0.111 0.167 -9999.0 0.0 -0.386 108.0 108.0 NPHS2 -0.084 0.204 -9999.0 0.0 -0.561 66.0 66.0 mol:IP3 -0.111 0.167 -9999.0 0.0 -0.386 108.0 108.0 regulation of endocytosis -0.082 0.158 -9999.0 0.0 -0.343 108.0 108.0 Nephrin/NEPH1/podocin/Cholesterol -0.114 0.17 -9999.0 0.0 -0.394 108.0 108.0 establishment of cell polarity -0.106 0.183 -9999.0 0.0 -0.401 115.0 115.0 Nephrin/NEPH1/podocin/NCK1-2 -0.1 0.152 -9999.0 0.0 -0.351 108.0 108.0 Nephrin/NEPH1/beta Arrestin2 -0.082 0.161 -9999.0 0.0 -0.347 108.0 108.0 NPHS1 -0.127 0.241 -9999.0 0.0 -0.536 110.0 110.0 Nephrin/NEPH1/podocin -0.093 0.169 -9999.0 0.0 -0.371 108.0 108.0 TJP1 0.007 0.044 -9999.0 0.0 -0.652 2.0 2.0 NCK1 0.01 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.01 0.0 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.112 0.168 -9999.0 0.0 -0.388 108.0 108.0 CD2AP 0.01 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 -0.112 0.168 -9999.0 0.0 -0.388 108.0 108.0 GRB2 0.01 0.0 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.093 0.173 -9999.0 0.0 -0.368 110.0 110.0 cytoskeleton organization -0.084 0.183 -9999.0 0.0 -0.399 105.0 105.0 Nephrin/NEPH1 -0.075 0.132 -9999.0 0.0 -0.352 74.0 74.0 Nephrin/NEPH1/ZO-1 -0.084 0.148 -9999.0 0.0 -0.402 70.0 70.0