Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.021 0.14 0.363 61.0 -9999.0 0.0 61.0 KIRREL 0.005 0.065 -9999.0 0.0 -0.5 5.0 5.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.021 0.14 -9999.0 0.0 -0.363 61.0 61.0 PLCG1 0.025 0.009 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.026 0.007 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.027 0.006 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.006 0.144 -9999.0 0.0 -0.279 93.0 93.0 ChemicalAbstracts:57-88-5 -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.028 0.114 -9999.0 0.0 -0.273 73.0 73.0 FYN -0.042 0.125 0.287 9.0 -0.264 95.0 104.0 mol:Ca2+ -0.006 0.134 -9999.0 0.0 -0.279 80.0 80.0 mol:DAG -0.005 0.135 -9999.0 0.0 -0.28 80.0 80.0 NPHS2 -0.03 0.148 -9999.0 0.0 -0.486 41.0 41.0 mol:IP3 -0.005 0.135 -9999.0 0.0 -0.28 80.0 80.0 regulation of endocytosis -0.012 0.127 -9999.0 0.0 -0.251 95.0 95.0 Nephrin/NEPH1/podocin/Cholesterol -0.018 0.136 -9999.0 0.0 -0.275 95.0 95.0 establishment of cell polarity -0.021 0.14 -9999.0 0.0 -0.363 61.0 61.0 Nephrin/NEPH1/podocin/NCK1-2 0.012 0.132 -9999.0 0.0 -0.262 77.0 77.0 Nephrin/NEPH1/beta Arrestin2 -0.011 0.13 -9999.0 0.0 -0.253 95.0 95.0 NPHS1 -0.041 0.173 -9999.0 0.0 -0.485 58.0 58.0 Nephrin/NEPH1/podocin -0.015 0.132 -9999.0 0.0 -0.265 95.0 95.0 TJP1 0.025 0.034 -9999.0 0.0 -0.477 2.0 2.0 NCK1 0.026 0.008 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.027 0.005 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.004 0.136 -9999.0 0.0 -0.282 80.0 80.0 CD2AP 0.027 0.006 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 -0.007 0.144 -9999.0 0.0 -0.279 93.0 93.0 GRB2 0.027 0.005 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.049 0.12 0.207 22.0 -0.258 91.0 113.0 cytoskeleton organization -0.051 0.129 0.204 6.0 -0.324 71.0 77.0 Nephrin/NEPH1 -0.01 0.1 -9999.0 0.0 -0.253 61.0 61.0 Nephrin/NEPH1/ZO-1 -0.003 0.122 -9999.0 0.0 -0.293 62.0 62.0