Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.1 0.246 0.533 115.0 -9999.0 0.0 115.0 KIRREL -0.046 0.196 -9999.0 0.0 -0.693 41.0 41.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.1 0.247 -9999.0 0.0 -0.534 115.0 115.0 PLCG1 0.027 0.005 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.026 0.007 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.026 0.006 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.056 0.205 -9999.0 0.0 -0.434 106.0 106.0 ChemicalAbstracts:57-88-5 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.057 0.159 -9999.0 0.0 -0.352 103.0 103.0 FYN -0.063 0.197 0.276 26.0 -0.409 106.0 132.0 mol:Ca2+ -0.056 0.201 -9999.0 0.0 -0.429 105.0 105.0 mol:DAG -0.055 0.202 -9999.0 0.0 -0.431 105.0 105.0 NPHS2 -0.005 0.053 -9999.0 0.0 -0.739 1.0 1.0 mol:IP3 -0.055 0.202 -9999.0 0.0 -0.431 105.0 105.0 regulation of endocytosis -0.05 0.181 -9999.0 0.0 -0.387 103.0 103.0 Nephrin/NEPH1/podocin/Cholesterol -0.068 0.199 -9999.0 0.0 -0.43 108.0 108.0 establishment of cell polarity -0.1 0.246 -9999.0 0.0 -0.533 115.0 115.0 Nephrin/NEPH1/podocin/NCK1-2 -0.04 0.197 -9999.0 0.0 -0.403 105.0 105.0 Nephrin/NEPH1/beta Arrestin2 -0.049 0.184 -9999.0 0.0 -0.392 103.0 103.0 NPHS1 -0.102 0.26 -9999.0 0.0 -0.675 84.0 84.0 Nephrin/NEPH1/podocin -0.061 0.19 -9999.0 0.0 -0.411 106.0 106.0 TJP1 0.027 0.004 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.027 0.003 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.027 0.005 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.055 0.204 -9999.0 0.0 -0.433 105.0 105.0 CD2AP 0.027 0.003 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 -0.055 0.202 -9999.0 0.0 -0.434 103.0 103.0 GRB2 0.026 0.007 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.077 0.196 0.277 21.0 -0.414 107.0 128.0 cytoskeleton organization -0.081 0.199 -9999.0 0.0 -0.453 102.0 102.0 Nephrin/NEPH1 -0.071 0.185 -9999.0 0.0 -0.393 115.0 115.0 Nephrin/NEPH1/ZO-1 -0.069 0.212 -9999.0 0.0 -0.452 109.0 109.0