Correlation between copy number variations of arm-level result and selected clinical features
Uterine Corpus Endometrioid Carcinoma (Primary solid tumor)
02 April 2015  |  analyses__2015_04_02
Maintainer Information
Citation Information
doi:10.7908/C17P8XH2
Maintained by TCGA GDAC Team (Broad Institute/MD Anderson Cancer Center/Harvard Medical School)
Cite as Broad Institute TCGA Genome Data Analysis Center (2015): Correlation between copy number variations of arm-level result and selected clinical features. Broad Institute of MIT and Harvard. doi:10.7908/C17P8XH2
Overview
Introduction

This pipeline computes the correlation between significant arm-level copy number variations (cnvs) and selected clinical features.

Summary

Testing the association between copy number variation 82 arm-level events and 7 clinical features across 528 patients, 231 significant findings detected with Q value < 0.25.

  • 1p gain cnv correlated to 'Time to Death',  'YEARS_TO_BIRTH',  'HISTOLOGICAL_TYPE',  'RADIATIONS_RADIATION_REGIMENINDICATION',  'COMPLETENESS_OF_RESECTION', and 'RACE'.

  • 1q gain cnv correlated to 'Time to Death' and 'YEARS_TO_BIRTH'.

  • 2p gain cnv correlated to 'Time to Death',  'YEARS_TO_BIRTH', and 'HISTOLOGICAL_TYPE'.

  • 2q gain cnv correlated to 'Time to Death',  'YEARS_TO_BIRTH', and 'HISTOLOGICAL_TYPE'.

  • 3p gain cnv correlated to 'HISTOLOGICAL_TYPE',  'RADIATIONS_RADIATION_REGIMENINDICATION', and 'RACE'.

  • 3q gain cnv correlated to 'Time to Death',  'YEARS_TO_BIRTH',  'HISTOLOGICAL_TYPE', and 'RACE'.

  • 4p gain cnv correlated to 'YEARS_TO_BIRTH',  'HISTOLOGICAL_TYPE', and 'RACE'.

  • 4q gain cnv correlated to 'HISTOLOGICAL_TYPE'.

  • 5p gain cnv correlated to 'Time to Death',  'YEARS_TO_BIRTH',  'HISTOLOGICAL_TYPE',  'RADIATIONS_RADIATION_REGIMENINDICATION', and 'COMPLETENESS_OF_RESECTION'.

  • 5q gain cnv correlated to 'HISTOLOGICAL_TYPE'.

  • 6p gain cnv correlated to 'YEARS_TO_BIRTH',  'HISTOLOGICAL_TYPE', and 'RACE'.

  • 6q gain cnv correlated to 'YEARS_TO_BIRTH',  'HISTOLOGICAL_TYPE',  'COMPLETENESS_OF_RESECTION', and 'RACE'.

  • 7p gain cnv correlated to 'Time to Death' and 'HISTOLOGICAL_TYPE'.

  • 7q gain cnv correlated to 'Time to Death' and 'HISTOLOGICAL_TYPE'.

  • 8p gain cnv correlated to 'Time to Death',  'YEARS_TO_BIRTH', and 'RADIATIONS_RADIATION_REGIMENINDICATION'.

  • 8q gain cnv correlated to 'Time to Death',  'HISTOLOGICAL_TYPE', and 'RADIATIONS_RADIATION_REGIMENINDICATION'.

  • 9p gain cnv correlated to 'ETHNICITY'.

  • 9q gain cnv correlated to 'COMPLETENESS_OF_RESECTION'.

  • 10p gain cnv correlated to 'YEARS_TO_BIRTH'.

  • 11p gain cnv correlated to 'HISTOLOGICAL_TYPE'.

  • 11q gain cnv correlated to 'Time to Death' and 'HISTOLOGICAL_TYPE'.

  • 12p gain cnv correlated to 'HISTOLOGICAL_TYPE' and 'RACE'.

  • 12q gain cnv correlated to 'Time to Death',  'HISTOLOGICAL_TYPE', and 'RACE'.

  • 13q gain cnv correlated to 'YEARS_TO_BIRTH' and 'HISTOLOGICAL_TYPE'.

  • 14q gain cnv correlated to 'HISTOLOGICAL_TYPE' and 'RADIATIONS_RADIATION_REGIMENINDICATION'.

  • 15q gain cnv correlated to 'Time to Death'.

  • 16p gain cnv correlated to 'YEARS_TO_BIRTH',  'HISTOLOGICAL_TYPE',  'RADIATIONS_RADIATION_REGIMENINDICATION', and 'RACE'.

  • 16q gain cnv correlated to 'HISTOLOGICAL_TYPE' and 'COMPLETENESS_OF_RESECTION'.

  • 17q gain cnv correlated to 'Time to Death',  'HISTOLOGICAL_TYPE',  'COMPLETENESS_OF_RESECTION', and 'RACE'.

  • 18p gain cnv correlated to 'Time to Death',  'YEARS_TO_BIRTH',  'HISTOLOGICAL_TYPE',  'COMPLETENESS_OF_RESECTION', and 'RACE'.

  • 18q gain cnv correlated to 'Time to Death',  'YEARS_TO_BIRTH',  'HISTOLOGICAL_TYPE', and 'COMPLETENESS_OF_RESECTION'.

  • 19p gain cnv correlated to 'YEARS_TO_BIRTH' and 'HISTOLOGICAL_TYPE'.

  • 19q gain cnv correlated to 'Time to Death',  'YEARS_TO_BIRTH',  'HISTOLOGICAL_TYPE', and 'RACE'.

  • 20p gain cnv correlated to 'Time to Death',  'YEARS_TO_BIRTH',  'HISTOLOGICAL_TYPE',  'RADIATIONS_RADIATION_REGIMENINDICATION',  'COMPLETENESS_OF_RESECTION', and 'RACE'.

  • 20q gain cnv correlated to 'Time to Death',  'YEARS_TO_BIRTH',  'HISTOLOGICAL_TYPE',  'RADIATIONS_RADIATION_REGIMENINDICATION',  'COMPLETENESS_OF_RESECTION', and 'RACE'.

  • 21q gain cnv correlated to 'Time to Death',  'YEARS_TO_BIRTH', and 'HISTOLOGICAL_TYPE'.

  • 22q gain cnv correlated to 'YEARS_TO_BIRTH',  'HISTOLOGICAL_TYPE', and 'COMPLETENESS_OF_RESECTION'.

  • xq gain cnv correlated to 'Time to Death'.

  • 1p loss cnv correlated to 'YEARS_TO_BIRTH',  'HISTOLOGICAL_TYPE', and 'COMPLETENESS_OF_RESECTION'.

  • 1q loss cnv correlated to 'HISTOLOGICAL_TYPE' and 'COMPLETENESS_OF_RESECTION'.

  • 2p loss cnv correlated to 'Time to Death'.

  • 2q loss cnv correlated to 'Time to Death'.

  • 3p loss cnv correlated to 'YEARS_TO_BIRTH' and 'HISTOLOGICAL_TYPE'.

  • 3q loss cnv correlated to 'YEARS_TO_BIRTH' and 'HISTOLOGICAL_TYPE'.

  • 4p loss cnv correlated to 'Time to Death',  'YEARS_TO_BIRTH',  'HISTOLOGICAL_TYPE', and 'RADIATIONS_RADIATION_REGIMENINDICATION'.

  • 4q loss cnv correlated to 'Time to Death',  'YEARS_TO_BIRTH',  'HISTOLOGICAL_TYPE', and 'RADIATIONS_RADIATION_REGIMENINDICATION'.

  • 5p loss cnv correlated to 'Time to Death',  'YEARS_TO_BIRTH', and 'HISTOLOGICAL_TYPE'.

  • 5q loss cnv correlated to 'Time to Death',  'YEARS_TO_BIRTH', and 'HISTOLOGICAL_TYPE'.

  • 6p loss cnv correlated to 'HISTOLOGICAL_TYPE'.

  • 6q loss cnv correlated to 'HISTOLOGICAL_TYPE'.

  • 7p loss cnv correlated to 'Time to Death',  'YEARS_TO_BIRTH', and 'HISTOLOGICAL_TYPE'.

  • 7q loss cnv correlated to 'YEARS_TO_BIRTH' and 'HISTOLOGICAL_TYPE'.

  • 8p loss cnv correlated to 'YEARS_TO_BIRTH',  'HISTOLOGICAL_TYPE', and 'RACE'.

  • 8q loss cnv correlated to 'HISTOLOGICAL_TYPE'.

  • 9p loss cnv correlated to 'Time to Death',  'YEARS_TO_BIRTH',  'HISTOLOGICAL_TYPE', and 'COMPLETENESS_OF_RESECTION'.

  • 9q loss cnv correlated to 'Time to Death',  'YEARS_TO_BIRTH', and 'HISTOLOGICAL_TYPE'.

  • 10p loss cnv correlated to 'Time to Death',  'YEARS_TO_BIRTH',  'HISTOLOGICAL_TYPE', and 'RACE'.

  • 10q loss cnv correlated to 'Time to Death',  'YEARS_TO_BIRTH', and 'HISTOLOGICAL_TYPE'.

  • 11p loss cnv correlated to 'Time to Death',  'YEARS_TO_BIRTH',  'HISTOLOGICAL_TYPE', and 'RADIATIONS_RADIATION_REGIMENINDICATION'.

  • 11q loss cnv correlated to 'Time to Death',  'YEARS_TO_BIRTH',  'HISTOLOGICAL_TYPE',  'RADIATIONS_RADIATION_REGIMENINDICATION', and 'RACE'.

  • 12p loss cnv correlated to 'Time to Death',  'YEARS_TO_BIRTH',  'HISTOLOGICAL_TYPE', and 'COMPLETENESS_OF_RESECTION'.

  • 12q loss cnv correlated to 'Time to Death',  'YEARS_TO_BIRTH', and 'HISTOLOGICAL_TYPE'.

  • 13q loss cnv correlated to 'Time to Death',  'YEARS_TO_BIRTH',  'HISTOLOGICAL_TYPE', and 'RADIATIONS_RADIATION_REGIMENINDICATION'.

  • 14q loss cnv correlated to 'Time to Death',  'YEARS_TO_BIRTH',  'HISTOLOGICAL_TYPE', and 'RACE'.

  • 15q loss cnv correlated to 'Time to Death',  'YEARS_TO_BIRTH',  'HISTOLOGICAL_TYPE', and 'RADIATIONS_RADIATION_REGIMENINDICATION'.

  • 16p loss cnv correlated to 'Time to Death',  'YEARS_TO_BIRTH',  'HISTOLOGICAL_TYPE',  'RADIATIONS_RADIATION_REGIMENINDICATION', and 'COMPLETENESS_OF_RESECTION'.

  • 16q loss cnv correlated to 'Time to Death',  'YEARS_TO_BIRTH',  'HISTOLOGICAL_TYPE',  'RADIATIONS_RADIATION_REGIMENINDICATION',  'COMPLETENESS_OF_RESECTION', and 'RACE'.

  • 17p loss cnv correlated to 'Time to Death',  'YEARS_TO_BIRTH',  'HISTOLOGICAL_TYPE', and 'RACE'.

  • 17q loss cnv correlated to 'Time to Death',  'YEARS_TO_BIRTH',  'HISTOLOGICAL_TYPE', and 'ETHNICITY'.

  • 18p loss cnv correlated to 'YEARS_TO_BIRTH' and 'HISTOLOGICAL_TYPE'.

  • 18q loss cnv correlated to 'YEARS_TO_BIRTH' and 'HISTOLOGICAL_TYPE'.

  • 19p loss cnv correlated to 'Time to Death' and 'HISTOLOGICAL_TYPE'.

  • 19q loss cnv correlated to 'Time to Death' and 'HISTOLOGICAL_TYPE'.

  • 20p loss cnv correlated to 'HISTOLOGICAL_TYPE'.

  • 20q loss cnv correlated to 'HISTOLOGICAL_TYPE' and 'RADIATIONS_RADIATION_REGIMENINDICATION'.

  • 21q loss cnv correlated to 'Time to Death',  'YEARS_TO_BIRTH', and 'HISTOLOGICAL_TYPE'.

  • 22q loss cnv correlated to 'Time to Death',  'YEARS_TO_BIRTH',  'HISTOLOGICAL_TYPE', and 'RADIATIONS_RADIATION_REGIMENINDICATION'.

  • xp loss cnv correlated to 'Time to Death',  'YEARS_TO_BIRTH',  'HISTOLOGICAL_TYPE', and 'RADIATIONS_RADIATION_REGIMENINDICATION'.

  • xq loss cnv correlated to 'Time to Death',  'YEARS_TO_BIRTH',  'HISTOLOGICAL_TYPE', and 'RADIATIONS_RADIATION_REGIMENINDICATION'.

Results
Overview of the results

Table 1.  Get Full Table Overview of the association between significant copy number variation of 82 arm-level events and 7 clinical features. Shown in the table are P values (Q values). Thresholded by Q value < 0.25, 231 significant findings detected.

Clinical
Features 		Time
to
Death 		YEARS
TO
BIRTH 		HISTOLOGICAL
TYPE 		RADIATIONS
RADIATION
REGIMENINDICATION 		COMPLETENESS
OF
RESECTION 		RACE ETHNICITY
nCNV (%) nWild-Type logrank test Wilcoxon-test Fisher's exact test Fisher's exact test Fisher's exact test Fisher's exact test Fisher's exact test
1p gain 49 (9%) 479 0.000418
(0.00296) 		0.0382
(0.117) 		1e-05
(9.9e-05) 		0.0169
(0.0636) 		0.0516
(0.149) 		0.0235
(0.0808) 		1
(1.00)
20p gain 110 (21%) 418 0.00803
(0.0347) 		5.83e-05
(0.000485) 		1e-05
(9.9e-05) 		0.00101
(0.00622) 		0.0674
(0.183) 		0.0835
(0.216) 		1
(1.00)
20q gain 130 (25%) 398 0.00116
(0.00705) 		4.45e-06
(9.9e-05) 		1e-05
(9.9e-05) 		0.0006
(0.00405) 		0.0171
(0.0643) 		0.00774
(0.0339) 		0.75
(0.852)
16q loss 136 (26%) 392 0.0184
(0.0676) 		3.9e-07
(7.47e-05) 		1e-05
(9.9e-05) 		0.0426
(0.128) 		0.0251
(0.0832) 		0.0327
(0.104) 		1
(1.00)
5p gain 50 (9%) 478 0.000141
(0.00105) 		0.0227
(0.0784) 		1e-05
(9.9e-05) 		0.0424
(0.128) 		0.093
(0.237) 		0.144
(0.311) 		0.64
(0.773)
18p gain 71 (13%) 457 0.00618
(0.028) 		0.00132
(0.00768) 		1e-05
(9.9e-05) 		0.313
(0.488) 		0.0246
(0.0828) 		0.00044
(0.00308) 		1
(1.00)
11q loss 72 (14%) 456 0.00962
(0.04) 		0.00307
(0.0162) 		1e-05
(9.9e-05) 		0.000876
(0.00565) 		0.163
(0.334) 		0.0767
(0.204) 		0.43
(0.601)
16p loss 96 (18%) 432 0.00321
(0.0166) 		4.74e-05
(0.000413) 		1e-05
(9.9e-05) 		0.0982
(0.245) 		0.0207
(0.0733) 		0.174
(0.347) 		0.725
(0.832)
3q gain 81 (15%) 447 0.00455
(0.0223) 		0.005
(0.0241) 		1e-05
(9.9e-05) 		0.222
(0.4) 		0.33
(0.505) 		0.00619
(0.028) 		1
(1.00)
6q gain 62 (12%) 466 0.4
(0.579) 		0.0585
(0.166) 		2e-05
(0.000188) 		0.879
(0.963) 		0.0521
(0.15) 		0.00574
(0.0268) 		1
(1.00)
16p gain 27 (5%) 501 0.413
(0.586) 		0.0178
(0.0663) 		0.0428
(0.128) 		0.0731
(0.196) 		0.181
(0.354) 		0.067
(0.183) 		0.536
(0.683)
17q gain 30 (6%) 498 0.00556
(0.0262) 		0.287
(0.468) 		3e-05
(0.000273) 		0.832
(0.921) 		0.0245
(0.0828) 		0.00803
(0.0347) 		0.604
(0.741)
18q gain 44 (8%) 484 9.16e-05
(0.000701) 		0.015
(0.0581) 		1e-05
(9.9e-05) 		0.598
(0.739) 		0.0134
(0.0526) 		0.188
(0.362) 		1
(1.00)
19q gain 55 (10%) 473 0.0196
(0.0714) 		1.72e-07
(4.94e-05) 		1e-05
(9.9e-05) 		0.874
(0.959) 		0.789
(0.882) 		0.0222
(0.0773) 		0.388
(0.569)
4p loss 100 (19%) 428 0.00128
(0.00758) 		7.21e-05
(0.000575) 		1e-05
(9.9e-05) 		0.0325
(0.104) 		0.519
(0.676) 		0.288
(0.468) 		0.492
(0.657)
4q loss 101 (19%) 427 0.00145
(0.00824) 		4.72e-05
(0.000413) 		1e-05
(9.9e-05) 		0.0247
(0.0828) 		0.577
(0.72) 		0.19
(0.365) 		1
(1.00)
9p loss 101 (19%) 427 0.00052
(0.0036) 		1.06e-05
(0.000103) 		1e-05
(9.9e-05) 		0.532
(0.683) 		0.0618
(0.171) 		0.609
(0.744) 		1
(1.00)
10p loss 42 (8%) 486 0.0283
(0.0917) 		0.0152
(0.0583) 		1e-05
(9.9e-05) 		0.147
(0.311) 		0.181
(0.354) 		0.0777
(0.205) 		0.618
(0.752)
11p loss 73 (14%) 455 0.00332
(0.017) 		0.00123
(0.00734) 		1e-05
(9.9e-05) 		0.0152
(0.0583) 		0.327
(0.503) 		0.123
(0.278) 		1
(1.00)
12p loss 42 (8%) 486 0.00266
(0.0144) 		0.0505
(0.147) 		1e-05
(9.9e-05) 		0.147
(0.311) 		0.0824
(0.214) 		0.53
(0.682) 		1
(1.00)
13q loss 89 (17%) 439 0.00368
(0.0187) 		0.0199
(0.0715) 		1e-05
(9.9e-05) 		0.025
(0.0832) 		0.493
(0.657) 		0.754
(0.853) 		0.3
(0.478)
14q loss 59 (11%) 469 0.011
(0.0443) 		0.00425
(0.0212) 		1e-05
(9.9e-05) 		0.349
(0.525) 		0.675
(0.802) 		0.00729
(0.0322) 		0.163
(0.334)
15q loss 105 (20%) 423 0.00117
(0.00705) 		2.54e-06
(9.9e-05) 		1e-05
(9.9e-05) 		0.0493
(0.144) 		0.356
(0.533) 		0.196
(0.369) 		0.745
(0.852)
17p loss 125 (24%) 403 0.000538
(0.00368) 		7.32e-06
(9.9e-05) 		1e-05
(9.9e-05) 		0.247
(0.425) 		0.209
(0.384) 		0.00859
(0.0364) 		0.751
(0.852)
17q loss 89 (17%) 439 0.00489
(0.0238) 		0.000168
(0.00123) 		1e-05
(9.9e-05) 		0.238
(0.416) 		0.56
(0.704) 		0.283
(0.466) 		0.0713
(0.192)
22q loss 106 (20%) 422 0.00604
(0.0277) 		6.81e-05
(0.000558) 		1e-05
(9.9e-05) 		0.049
(0.144) 		0.486
(0.653) 		0.119
(0.272) 		0.197
(0.369)
xp loss 80 (15%) 448 8.84e-05
(0.000686) 		0.000212
(0.00152) 		1e-05
(9.9e-05) 		0.0992
(0.246) 		0.136
(0.301) 		0.136
(0.301) 		0.25
(0.427)
xq loss 69 (13%) 459 0.00848
(0.0363) 		0.000693
(0.00452) 		1e-05
(9.9e-05) 		0.0789
(0.207) 		0.207
(0.381) 		0.144
(0.311) 		0.115
(0.267)
2p gain 93 (18%) 435 8.08e-05
(0.000635) 		0.00421
(0.0212) 		1e-05
(9.9e-05) 		0.246
(0.424) 		0.553
(0.696) 		0.78
(0.876) 		0.145
(0.311)
2q gain 78 (15%) 450 0.000118
(0.00089) 		0.0287
(0.0927) 		1e-05
(9.9e-05) 		0.127
(0.287) 		0.225
(0.403) 		0.953
(1.00) 		0.241
(0.417)
3p gain 46 (9%) 482 0.122
(0.277) 		0.37
(0.549) 		0.00094
(0.00593) 		0.0349
(0.109) 		0.449
(0.615) 		0.0209
(0.0736) 		1
(1.00)
4p gain 14 (3%) 514 0.195
(0.368) 		0.0121
(0.048) 		0.00199
(0.0111) 		1
(1.00) 		0.111
(0.262) 		0.0254
(0.0839) 		0.289
(0.468)
6p gain 78 (15%) 450 0.2
(0.374) 		0.0215
(0.0753) 		1e-05
(9.9e-05) 		0.49
(0.657) 		0.158
(0.326) 		0.0343
(0.107) 		0.703
(0.819)
8p gain 117 (22%) 411 0.0374
(0.115) 		0.0965
(0.243) 		0.723
(0.832) 		0.0975
(0.244) 		0.142
(0.31) 		0.444
(0.611) 		0.535
(0.683)
8q gain 157 (30%) 371 0.00211
(0.0116) 		0.952
(1.00) 		0.00276
(0.0148) 		0.0406
(0.123) 		0.191
(0.365) 		0.682
(0.804) 		0.241
(0.417)
12q gain 53 (10%) 475 0.0636
(0.175) 		0.501
(0.66) 		0.0366
(0.114) 		0.103
(0.25) 		0.6
(0.739) 		0.0876
(0.224) 		0.381
(0.559)
21q gain 38 (7%) 490 0.0261
(0.0857) 		0.000956
(0.00597) 		1e-05
(9.9e-05) 		0.26
(0.437) 		0.353
(0.53) 		0.176
(0.349) 		0.611
(0.745)
22q gain 31 (6%) 497 0.147
(0.311) 		0.00321
(0.0166) 		1e-05
(9.9e-05) 		0.68
(0.803) 		0.0336
(0.106) 		0.232
(0.411) 		1
(1.00)
1p loss 25 (5%) 503 0.497
(0.659) 		0.0382
(0.117) 		1e-05
(9.9e-05) 		1
(1.00) 		0.00279
(0.0148) 		0.668
(0.798) 		1
(1.00)
5p loss 54 (10%) 474 0.0281
(0.0917) 		0.0861
(0.222) 		1e-05
(9.9e-05) 		0.257
(0.435) 		0.158
(0.326) 		0.42
(0.594) 		0.154
(0.321)
5q loss 73 (14%) 455 0.00538
(0.0255) 		0.000677
(0.00452) 		1e-05
(9.9e-05) 		0.67
(0.798) 		0.709
(0.821) 		0.404
(0.582) 		0.109
(0.259)
7p loss 43 (8%) 485 0.0457
(0.135) 		4.87e-05
(0.000417) 		1e-05
(9.9e-05) 		0.72
(0.831) 		0.31
(0.487) 		0.103
(0.25) 		1
(1.00)
8p loss 78 (15%) 450 0.231
(0.411) 		4.75e-05
(0.000413) 		1e-05
(9.9e-05) 		0.679
(0.803) 		0.423
(0.595) 		0.0333
(0.106) 		0.703
(0.819)
9q loss 120 (23%) 408 0.000927
(0.00591) 		4.51e-09
(2.59e-06) 		1e-05
(9.9e-05) 		0.291
(0.469) 		0.236
(0.414) 		0.176
(0.349) 		0.536
(0.683)
10q loss 39 (7%) 489 0.0639
(0.176) 		0.0124
(0.0493) 		1e-05
(9.9e-05) 		0.131
(0.294) 		0.776
(0.875) 		0.251
(0.428) 		1
(1.00)
12q loss 35 (7%) 493 0.00069
(0.00452) 		0.0589
(0.166) 		1e-05
(9.9e-05) 		0.236
(0.414) 		0.746
(0.852) 		0.401
(0.579) 		0.604
(0.741)
21q loss 53 (10%) 475 0.059
(0.166) 		0.00922
(0.0386) 		1e-05
(9.9e-05) 		1
(1.00) 		0.367
(0.546) 		0.343
(0.52) 		1
(1.00)
1q gain 182 (34%) 346 0.0709
(0.192) 		0.0069
(0.0307) 		0.599
(0.739) 		0.607
(0.742) 		0.995
(1.00) 		0.528
(0.682) 		0.152
(0.319)
7p gain 65 (12%) 463 0.0167
(0.0633) 		0.214
(0.387) 		0.0533
(0.153) 		0.231
(0.411) 		0.582
(0.724) 		0.796
(0.887) 		0.704
(0.819)
7q gain 64 (12%) 464 0.000175
(0.00127) 		0.183
(0.356) 		0.0808
(0.211) 		0.134
(0.3) 		0.63
(0.764) 		0.858
(0.945) 		1
(1.00)
11q gain 18 (3%) 510 0.00447
(0.0221) 		0.299
(0.478) 		0.0179
(0.0664) 		0.791
(0.884) 		0.292
(0.469) 		0.552
(0.696) 		1
(1.00)
12p gain 70 (13%) 458 0.18
(0.354) 		0.575
(0.719) 		1e-05
(9.9e-05) 		0.111
(0.262) 		0.652
(0.783) 		0.0605
(0.17) 		0.241
(0.417)
13q gain 29 (5%) 499 0.779
(0.876) 		0.0118
(0.0474) 		1e-05
(9.9e-05) 		0.666
(0.796) 		0.236
(0.414) 		0.441
(0.609) 		1
(1.00)
14q gain 36 (7%) 492 0.103
(0.25) 		0.32
(0.496) 		1e-05
(9.9e-05) 		0.00993
(0.0407) 		0.336
(0.511) 		0.234
(0.413) 		1
(1.00)
16q gain 10 (2%) 518 0.868
(0.954) 		0.217
(0.391) 		0.0951
(0.241) 		0.303
(0.478) 		0.00243
(0.0133) 		0.115
(0.267) 		0.261
(0.437)
19p gain 52 (10%) 476 0.146
(0.311) 		1.83e-06
(9.9e-05) 		1e-05
(9.9e-05) 		0.411
(0.585) 		0.81
(0.9) 		0.184
(0.357) 		1
(1.00)
1q loss 14 (3%) 514 0.136
(0.301) 		0.303
(0.478) 		7e-05
(0.000566) 		0.372
(0.551) 		0.0192
(0.0703) 		0.457
(0.621) 		1
(1.00)
3p loss 50 (9%) 478 0.171
(0.346) 		0.00589
(0.0273) 		1e-05
(9.9e-05) 		0.504
(0.66) 		0.978
(1.00) 		0.548
(0.693) 		0.378
(0.556)
3q loss 30 (6%) 498 0.979
(1.00) 		0.0553
(0.158) 		3e-05
(0.000273) 		0.287
(0.468) 		0.409
(0.584) 		0.107
(0.257) 		1
(1.00)
7q loss 41 (8%) 487 0.455
(0.621) 		0.0013
(0.00763) 		1e-05
(9.9e-05) 		0.583
(0.724) 		0.656
(0.786) 		0.324
(0.5) 		1
(1.00)
18p loss 50 (9%) 478 0.529
(0.682) 		0.0205
(0.0731) 		5e-05
(0.000422) 		0.179
(0.353) 		0.186
(0.359) 		0.933
(1.00) 		1
(1.00)
18q loss 63 (12%) 465 0.503
(0.66) 		0.0199
(0.0715) 		1e-05
(9.9e-05) 		0.172
(0.346) 		0.153
(0.32) 		0.395
(0.575) 		1
(1.00)
19p loss 59 (11%) 469 0.00181
(0.0102) 		0.101
(0.25) 		1e-05
(9.9e-05) 		0.642
(0.775) 		0.109
(0.26) 		0.499
(0.659) 		0.212
(0.385)
19q loss 56 (11%) 472 0.00514
(0.0246) 		0.13
(0.294) 		1e-05
(9.9e-05) 		0.263
(0.438) 		0.172
(0.346) 		0.357
(0.533) 		0.173
(0.346)
20q loss 9 (2%) 519 0.192
(0.367) 		0.727
(0.833) 		0.00687
(0.0307) 		0.0618
(0.171) 		1
(1.00) 		0.461
(0.623) 		1
(1.00)
4q gain 8 (2%) 520 0.71
(0.821) 		0.461
(0.623) 		0.0452
(0.134) 		0.688
(0.808) 		0.492
(0.657) 		0.336
(0.511) 		0.14
(0.307)
5q gain 19 (4%) 509 0.167
(0.341) 		0.592
(0.734) 		0.0014
(0.00804) 		0.428
(0.599) 		0.261
(0.437) 		0.405
(0.583) 		1
(1.00)
9p gain 21 (4%) 507 0.776
(0.875) 		0.909
(0.994) 		0.116
(0.268) 		0.312
(0.488) 		0.275
(0.453) 		0.435
(0.604) 		0.0139
(0.0542)
9q gain 8 (2%) 520 0.722
(0.832) 		0.701
(0.819) 		0.25
(0.427) 		0.688
(0.808) 		0.0754
(0.201) 		0.117
(0.27) 		0.202
(0.376)
10p gain 115 (22%) 413 0.706
(0.82) 		0.0944
(0.24) 		0.75
(0.852) 		0.406
(0.583) 		0.57
(0.714) 		0.296
(0.475) 		0.205
(0.379)
11p gain 22 (4%) 506 0.146
(0.311) 		0.121
(0.276) 		2e-05
(0.000188) 		0.808
(0.899) 		0.329
(0.505) 		0.426
(0.598) 		0.457
(0.621)
15q gain 10 (2%) 518 0.0238
(0.0813) 		0.441
(0.609) 		0.645
(0.777) 		0.303
(0.478) 		0.112
(0.262) 		0.434
(0.604) 		0.289
(0.468)
xq gain 63 (12%) 465 0.00863
(0.0364) 		0.195
(0.368) 		0.311
(0.487) 		0.45
(0.615) 		0.157
(0.326) 		1
(1.00) 		1
(1.00)
2p loss 11 (2%) 517 0.0774
(0.205) 		0.197
(0.369) 		0.446
(0.612) 		0.303
(0.478) 		0.14
(0.307) 		0.392
(0.572) 		0.315
(0.489)
2q loss 17 (3%) 511 0.0104
(0.0423) 		0.106
(0.254) 		0.334
(0.509) 		0.262
(0.438) 		0.398
(0.578) 		0.528
(0.682) 		0.436
(0.604)
6p loss 17 (3%) 511 0.912
(0.995) 		0.145
(0.311) 		1e-05
(9.9e-05) 		0.784
(0.879) 		0.509
(0.665) 		0.68
(0.803) 		0.366
(0.546)
6q loss 25 (5%) 503 0.472
(0.636) 		0.227
(0.405) 		1e-05
(9.9e-05) 		0.821
(0.91) 		0.408
(0.584) 		1
(1.00) 		0.498
(0.659)
8q loss 24 (5%) 504 0.542
(0.688) 		0.194
(0.368) 		1e-05
(9.9e-05) 		0.64
(0.773) 		0.346
(0.523) 		0.266
(0.441) 		0.498
(0.659)
20p loss 18 (3%) 510 1
(1.00) 		0.173
(0.346) 		0.00972
(0.0401) 		0.103
(0.25) 		0.152
(0.319) 		0.423
(0.595) 		0.413
(0.586)
10q gain 108 (20%) 420 0.526
(0.682) 		0.536
(0.683) 		0.834
(0.921) 		0.543
(0.688) 		0.21
(0.384) 		0.212
(0.385) 		1
(1.00)
17p gain 12 (2%) 516 0.103
(0.25) 		0.515
(0.672) 		0.254
(0.432) 		1
(1.00) 		0.104
(0.25) 		1
(1.00) 		0.315
(0.489)
xp gain 64 (12%) 464 0.271
(0.448) 		0.257
(0.435) 		0.378
(0.556) 		0.291
(0.469) 		0.205
(0.379) 		0.966
(1.00) 		1
(1.00)
'1p gain' versus 'Time to Death'

P value = 0.000418 (logrank test), Q value = 0.003

Table S1.  Gene #1: '1p gain' versus Clinical Feature #1: 'Time to Death'

nPatients nDeath Duration Range (Median), Month
ALL 526 69 0.1 - 191.8 (23.3)
1P GAIN MUTATED 49 12 0.1 - 72.6 (17.9)
1P GAIN WILD-TYPE 477 57 0.2 - 191.8 (23.9)

Figure S1.  Get High-res Image Gene #1: '1p gain' versus Clinical Feature #1: 'Time to Death'

'1p gain' versus 'YEARS_TO_BIRTH'

P value = 0.0382 (Wilcoxon-test), Q value = 0.12

Table S2.  Gene #1: '1p gain' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

nPatients Mean (Std.Dev)
ALL 526 64.0 (11.2)
1P GAIN MUTATED 49 67.1 (9.4)
1P GAIN WILD-TYPE 477 63.7 (11.4)

Figure S2.  Get High-res Image Gene #1: '1p gain' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

'1p gain' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 9.9e-05

Table S3.  Gene #1: '1p gain' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 395 21 112
1P GAIN MUTATED 21 2 26
1P GAIN WILD-TYPE 374 19 86

Figure S3.  Get High-res Image Gene #1: '1p gain' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

'1p gain' versus 'RADIATIONS_RADIATION_REGIMENINDICATION'

P value = 0.0169 (Fisher's exact test), Q value = 0.064

Table S4.  Gene #1: '1p gain' versus Clinical Feature #4: 'RADIATIONS_RADIATION_REGIMENINDICATION'

nPatients NO YES
ALL 141 387
1P GAIN MUTATED 6 43
1P GAIN WILD-TYPE 135 344

Figure S4.  Get High-res Image Gene #1: '1p gain' versus Clinical Feature #4: 'RADIATIONS_RADIATION_REGIMENINDICATION'

'1p gain' versus 'COMPLETENESS_OF_RESECTION'

P value = 0.0516 (Fisher's exact test), Q value = 0.15

Table S5.  Gene #1: '1p gain' versus Clinical Feature #5: 'COMPLETENESS_OF_RESECTION'

nPatients R0 R1 R2 RX
ALL 363 23 17 35
1P GAIN MUTATED 31 0 2 7
1P GAIN WILD-TYPE 332 23 15 28

Figure S5.  Get High-res Image Gene #1: '1p gain' versus Clinical Feature #5: 'COMPLETENESS_OF_RESECTION'

'1p gain' versus 'RACE'

P value = 0.0235 (Fisher's exact test), Q value = 0.081

Table S6.  Gene #1: '1p gain' versus Clinical Feature #6: 'RACE'

nPatients AMERICAN INDIAN OR ALASKA NATIVE ASIAN BLACK OR AFRICAN AMERICAN NATIVE HAWAIIAN OR OTHER PACIFIC ISLANDER WHITE
ALL 4 20 101 9 366
1P GAIN MUTATED 0 1 17 2 26
1P GAIN WILD-TYPE 4 19 84 7 340

Figure S6.  Get High-res Image Gene #1: '1p gain' versus Clinical Feature #6: 'RACE'

'1q gain' versus 'Time to Death'

P value = 0.0709 (logrank test), Q value = 0.19

Table S7.  Gene #2: '1q gain' versus Clinical Feature #1: 'Time to Death'

nPatients nDeath Duration Range (Median), Month
ALL 526 69 0.1 - 191.8 (23.3)
1Q GAIN MUTATED 182 29 0.1 - 118.0 (20.9)
1Q GAIN WILD-TYPE 344 40 0.2 - 191.8 (23.9)

Figure S7.  Get High-res Image Gene #2: '1q gain' versus Clinical Feature #1: 'Time to Death'

'1q gain' versus 'YEARS_TO_BIRTH'

P value = 0.0069 (Wilcoxon-test), Q value = 0.031

Table S8.  Gene #2: '1q gain' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

nPatients Mean (Std.Dev)
ALL 526 64.0 (11.2)
1Q GAIN MUTATED 182 66.0 (10.3)
1Q GAIN WILD-TYPE 344 63.0 (11.6)

Figure S8.  Get High-res Image Gene #2: '1q gain' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

'2p gain' versus 'Time to Death'

P value = 8.08e-05 (logrank test), Q value = 0.00064

Table S9.  Gene #3: '2p gain' versus Clinical Feature #1: 'Time to Death'

nPatients nDeath Duration Range (Median), Month
ALL 526 69 0.1 - 191.8 (23.3)
2P GAIN MUTATED 92 23 0.1 - 149.6 (20.8)
2P GAIN WILD-TYPE 434 46 0.1 - 191.8 (23.9)

Figure S9.  Get High-res Image Gene #3: '2p gain' versus Clinical Feature #1: 'Time to Death'

'2p gain' versus 'YEARS_TO_BIRTH'

P value = 0.00421 (Wilcoxon-test), Q value = 0.021

Table S10.  Gene #3: '2p gain' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

nPatients Mean (Std.Dev)
ALL 526 64.0 (11.2)
2P GAIN MUTATED 92 67.0 (10.4)
2P GAIN WILD-TYPE 434 63.4 (11.3)

Figure S10.  Get High-res Image Gene #3: '2p gain' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

'2p gain' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 9.9e-05

Table S11.  Gene #3: '2p gain' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 395 21 112
2P GAIN MUTATED 42 5 46
2P GAIN WILD-TYPE 353 16 66

Figure S11.  Get High-res Image Gene #3: '2p gain' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

'2q gain' versus 'Time to Death'

P value = 0.000118 (logrank test), Q value = 0.00089

Table S12.  Gene #4: '2q gain' versus Clinical Feature #1: 'Time to Death'

nPatients nDeath Duration Range (Median), Month
ALL 526 69 0.1 - 191.8 (23.3)
2Q GAIN MUTATED 77 19 0.1 - 110.1 (20.8)
2Q GAIN WILD-TYPE 449 50 0.1 - 191.8 (23.9)

Figure S12.  Get High-res Image Gene #4: '2q gain' versus Clinical Feature #1: 'Time to Death'

'2q gain' versus 'YEARS_TO_BIRTH'

P value = 0.0287 (Wilcoxon-test), Q value = 0.093

Table S13.  Gene #4: '2q gain' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

nPatients Mean (Std.Dev)
ALL 526 64.0 (11.2)
2Q GAIN MUTATED 77 66.5 (10.3)
2Q GAIN WILD-TYPE 449 63.6 (11.3)

Figure S13.  Get High-res Image Gene #4: '2q gain' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

'2q gain' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 9.9e-05

Table S14.  Gene #4: '2q gain' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 395 21 112
2Q GAIN MUTATED 37 4 37
2Q GAIN WILD-TYPE 358 17 75

Figure S14.  Get High-res Image Gene #4: '2q gain' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

'3p gain' versus 'HISTOLOGICAL_TYPE'

P value = 0.00094 (Fisher's exact test), Q value = 0.0059

Table S15.  Gene #5: '3p gain' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 395 21 112
3P GAIN MUTATED 26 0 20
3P GAIN WILD-TYPE 369 21 92

Figure S15.  Get High-res Image Gene #5: '3p gain' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

'3p gain' versus 'RADIATIONS_RADIATION_REGIMENINDICATION'

P value = 0.0349 (Fisher's exact test), Q value = 0.11

Table S16.  Gene #5: '3p gain' versus Clinical Feature #4: 'RADIATIONS_RADIATION_REGIMENINDICATION'

nPatients NO YES
ALL 141 387
3P GAIN MUTATED 6 40
3P GAIN WILD-TYPE 135 347

Figure S16.  Get High-res Image Gene #5: '3p gain' versus Clinical Feature #4: 'RADIATIONS_RADIATION_REGIMENINDICATION'

'3p gain' versus 'RACE'

P value = 0.0209 (Fisher's exact test), Q value = 0.074

Table S17.  Gene #5: '3p gain' versus Clinical Feature #6: 'RACE'

nPatients AMERICAN INDIAN OR ALASKA NATIVE ASIAN BLACK OR AFRICAN AMERICAN NATIVE HAWAIIAN OR OTHER PACIFIC ISLANDER WHITE
ALL 4 20 101 9 366
3P GAIN MUTATED 0 0 14 3 27
3P GAIN WILD-TYPE 4 20 87 6 339

Figure S17.  Get High-res Image Gene #5: '3p gain' versus Clinical Feature #6: 'RACE'

'3q gain' versus 'Time to Death'

P value = 0.00455 (logrank test), Q value = 0.022

Table S18.  Gene #6: '3q gain' versus Clinical Feature #1: 'Time to Death'

nPatients nDeath Duration Range (Median), Month
ALL 526 69 0.1 - 191.8 (23.3)
3Q GAIN MUTATED 81 18 0.1 - 191.8 (17.9)
3Q GAIN WILD-TYPE 445 51 0.2 - 185.8 (23.7)

Figure S18.  Get High-res Image Gene #6: '3q gain' versus Clinical Feature #1: 'Time to Death'

'3q gain' versus 'YEARS_TO_BIRTH'

P value = 0.005 (Wilcoxon-test), Q value = 0.024

Table S19.  Gene #6: '3q gain' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

nPatients Mean (Std.Dev)
ALL 526 64.0 (11.2)
3Q GAIN MUTATED 81 67.0 (9.7)
3Q GAIN WILD-TYPE 445 63.5 (11.4)

Figure S19.  Get High-res Image Gene #6: '3q gain' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

'3q gain' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 9.9e-05

Table S20.  Gene #6: '3q gain' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 395 21 112
3Q GAIN MUTATED 35 4 42
3Q GAIN WILD-TYPE 360 17 70

Figure S20.  Get High-res Image Gene #6: '3q gain' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

'3q gain' versus 'RACE'

P value = 0.00619 (Fisher's exact test), Q value = 0.028

Table S21.  Gene #6: '3q gain' versus Clinical Feature #6: 'RACE'

nPatients AMERICAN INDIAN OR ALASKA NATIVE ASIAN BLACK OR AFRICAN AMERICAN NATIVE HAWAIIAN OR OTHER PACIFIC ISLANDER WHITE
ALL 4 20 101 9 366
3Q GAIN MUTATED 0 3 26 3 44
3Q GAIN WILD-TYPE 4 17 75 6 322

Figure S21.  Get High-res Image Gene #6: '3q gain' versus Clinical Feature #6: 'RACE'

'4p gain' versus 'YEARS_TO_BIRTH'

P value = 0.0121 (Wilcoxon-test), Q value = 0.048

Table S22.  Gene #7: '4p gain' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

nPatients Mean (Std.Dev)
ALL 526 64.0 (11.2)
4P GAIN MUTATED 14 70.3 (10.4)
4P GAIN WILD-TYPE 512 63.8 (11.2)

Figure S22.  Get High-res Image Gene #7: '4p gain' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

'4p gain' versus 'HISTOLOGICAL_TYPE'

P value = 0.00199 (Fisher's exact test), Q value = 0.011

Table S23.  Gene #7: '4p gain' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 395 21 112
4P GAIN MUTATED 5 0 9
4P GAIN WILD-TYPE 390 21 103

Figure S23.  Get High-res Image Gene #7: '4p gain' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

'4p gain' versus 'RACE'

P value = 0.0254 (Fisher's exact test), Q value = 0.084

Table S24.  Gene #7: '4p gain' versus Clinical Feature #6: 'RACE'

nPatients AMERICAN INDIAN OR ALASKA NATIVE ASIAN BLACK OR AFRICAN AMERICAN NATIVE HAWAIIAN OR OTHER PACIFIC ISLANDER WHITE
ALL 4 20 101 9 366
4P GAIN MUTATED 0 2 6 0 5
4P GAIN WILD-TYPE 4 18 95 9 361

Figure S24.  Get High-res Image Gene #7: '4p gain' versus Clinical Feature #6: 'RACE'

'4q gain' versus 'HISTOLOGICAL_TYPE'

P value = 0.0452 (Fisher's exact test), Q value = 0.13

Table S25.  Gene #8: '4q gain' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 395 21 112
4Q GAIN MUTATED 3 0 5
4Q GAIN WILD-TYPE 392 21 107

Figure S25.  Get High-res Image Gene #8: '4q gain' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

'5p gain' versus 'Time to Death'

P value = 0.000141 (logrank test), Q value = 0.0011

Table S26.  Gene #9: '5p gain' versus Clinical Feature #1: 'Time to Death'

nPatients nDeath Duration Range (Median), Month
ALL 526 69 0.1 - 191.8 (23.3)
5P GAIN MUTATED 50 14 0.4 - 110.1 (20.4)
5P GAIN WILD-TYPE 476 55 0.1 - 191.8 (23.4)

Figure S26.  Get High-res Image Gene #9: '5p gain' versus Clinical Feature #1: 'Time to Death'

'5p gain' versus 'YEARS_TO_BIRTH'

P value = 0.0227 (Wilcoxon-test), Q value = 0.078

Table S27.  Gene #9: '5p gain' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

nPatients Mean (Std.Dev)
ALL 526 64.0 (11.2)
5P GAIN MUTATED 50 67.2 (9.8)
5P GAIN WILD-TYPE 476 63.7 (11.3)

Figure S27.  Get High-res Image Gene #9: '5p gain' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

'5p gain' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 9.9e-05

Table S28.  Gene #9: '5p gain' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 395 21 112
5P GAIN MUTATED 16 3 31
5P GAIN WILD-TYPE 379 18 81

Figure S28.  Get High-res Image Gene #9: '5p gain' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

'5p gain' versus 'RADIATIONS_RADIATION_REGIMENINDICATION'

P value = 0.0424 (Fisher's exact test), Q value = 0.13

Table S29.  Gene #9: '5p gain' versus Clinical Feature #4: 'RADIATIONS_RADIATION_REGIMENINDICATION'

nPatients NO YES
ALL 141 387
5P GAIN MUTATED 7 43
5P GAIN WILD-TYPE 134 344

Figure S29.  Get High-res Image Gene #9: '5p gain' versus Clinical Feature #4: 'RADIATIONS_RADIATION_REGIMENINDICATION'

'5p gain' versus 'COMPLETENESS_OF_RESECTION'

P value = 0.093 (Fisher's exact test), Q value = 0.24

Table S30.  Gene #9: '5p gain' versus Clinical Feature #5: 'COMPLETENESS_OF_RESECTION'

nPatients R0 R1 R2 RX
ALL 363 23 17 35
5P GAIN MUTATED 35 2 5 4
5P GAIN WILD-TYPE 328 21 12 31

Figure S30.  Get High-res Image Gene #9: '5p gain' versus Clinical Feature #5: 'COMPLETENESS_OF_RESECTION'

'5q gain' versus 'HISTOLOGICAL_TYPE'

P value = 0.0014 (Fisher's exact test), Q value = 0.008

Table S31.  Gene #10: '5q gain' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 395 21 112
5Q GAIN MUTATED 8 0 11
5Q GAIN WILD-TYPE 387 21 101

Figure S31.  Get High-res Image Gene #10: '5q gain' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

'6p gain' versus 'YEARS_TO_BIRTH'

P value = 0.0215 (Wilcoxon-test), Q value = 0.075

Table S32.  Gene #11: '6p gain' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

nPatients Mean (Std.Dev)
ALL 526 64.0 (11.2)
6P GAIN MUTATED 78 66.3 (9.7)
6P GAIN WILD-TYPE 448 63.6 (11.4)

Figure S32.  Get High-res Image Gene #11: '6p gain' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

'6p gain' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 9.9e-05

Table S33.  Gene #11: '6p gain' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 395 21 112
6P GAIN MUTATED 37 1 40
6P GAIN WILD-TYPE 358 20 72

Figure S33.  Get High-res Image Gene #11: '6p gain' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

'6p gain' versus 'RACE'

P value = 0.0343 (Fisher's exact test), Q value = 0.11

Table S34.  Gene #11: '6p gain' versus Clinical Feature #6: 'RACE'

nPatients AMERICAN INDIAN OR ALASKA NATIVE ASIAN BLACK OR AFRICAN AMERICAN NATIVE HAWAIIAN OR OTHER PACIFIC ISLANDER WHITE
ALL 4 20 101 9 366
6P GAIN MUTATED 0 2 25 2 46
6P GAIN WILD-TYPE 4 18 76 7 320

Figure S34.  Get High-res Image Gene #11: '6p gain' versus Clinical Feature #6: 'RACE'

'6q gain' versus 'YEARS_TO_BIRTH'

P value = 0.0585 (Wilcoxon-test), Q value = 0.17

Table S35.  Gene #12: '6q gain' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

nPatients Mean (Std.Dev)
ALL 526 64.0 (11.2)
6Q GAIN MUTATED 62 66.1 (10.2)
6Q GAIN WILD-TYPE 464 63.7 (11.3)

Figure S35.  Get High-res Image Gene #12: '6q gain' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

'6q gain' versus 'HISTOLOGICAL_TYPE'

P value = 2e-05 (Fisher's exact test), Q value = 0.00019

Table S36.  Gene #12: '6q gain' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 395 21 112
6Q GAIN MUTATED 32 1 29
6Q GAIN WILD-TYPE 363 20 83

Figure S36.  Get High-res Image Gene #12: '6q gain' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

'6q gain' versus 'COMPLETENESS_OF_RESECTION'

P value = 0.0521 (Fisher's exact test), Q value = 0.15

Table S37.  Gene #12: '6q gain' versus Clinical Feature #5: 'COMPLETENESS_OF_RESECTION'

nPatients R0 R1 R2 RX
ALL 363 23 17 35
6Q GAIN MUTATED 35 1 3 8
6Q GAIN WILD-TYPE 328 22 14 27

Figure S37.  Get High-res Image Gene #12: '6q gain' versus Clinical Feature #5: 'COMPLETENESS_OF_RESECTION'

'6q gain' versus 'RACE'

P value = 0.00574 (Fisher's exact test), Q value = 0.027

Table S38.  Gene #12: '6q gain' versus Clinical Feature #6: 'RACE'

nPatients AMERICAN INDIAN OR ALASKA NATIVE ASIAN BLACK OR AFRICAN AMERICAN NATIVE HAWAIIAN OR OTHER PACIFIC ISLANDER WHITE
ALL 4 20 101 9 366
6Q GAIN MUTATED 0 1 23 2 35
6Q GAIN WILD-TYPE 4 19 78 7 331

Figure S38.  Get High-res Image Gene #12: '6q gain' versus Clinical Feature #6: 'RACE'

'7p gain' versus 'Time to Death'

P value = 0.0167 (logrank test), Q value = 0.063

Table S39.  Gene #13: '7p gain' versus Clinical Feature #1: 'Time to Death'

nPatients nDeath Duration Range (Median), Month
ALL 526 69 0.1 - 191.8 (23.3)
7P GAIN MUTATED 64 13 0.2 - 125.4 (18.4)
7P GAIN WILD-TYPE 462 56 0.1 - 191.8 (24.1)

Figure S39.  Get High-res Image Gene #13: '7p gain' versus Clinical Feature #1: 'Time to Death'

'7p gain' versus 'HISTOLOGICAL_TYPE'

P value = 0.0533 (Fisher's exact test), Q value = 0.15

Table S40.  Gene #13: '7p gain' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 395 21 112
7P GAIN MUTATED 41 4 20
7P GAIN WILD-TYPE 354 17 92

Figure S40.  Get High-res Image Gene #13: '7p gain' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

'7q gain' versus 'Time to Death'

P value = 0.000175 (logrank test), Q value = 0.0013

Table S41.  Gene #14: '7q gain' versus Clinical Feature #1: 'Time to Death'

nPatients nDeath Duration Range (Median), Month
ALL 526 69 0.1 - 191.8 (23.3)
7Q GAIN MUTATED 63 16 0.2 - 125.4 (17.9)
7Q GAIN WILD-TYPE 463 53 0.1 - 191.8 (24.1)

Figure S41.  Get High-res Image Gene #14: '7q gain' versus Clinical Feature #1: 'Time to Death'

'7q gain' versus 'HISTOLOGICAL_TYPE'

P value = 0.0808 (Fisher's exact test), Q value = 0.21

Table S42.  Gene #14: '7q gain' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 395 21 112
7Q GAIN MUTATED 41 4 19
7Q GAIN WILD-TYPE 354 17 93

Figure S42.  Get High-res Image Gene #14: '7q gain' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

'8p gain' versus 'Time to Death'

P value = 0.0374 (logrank test), Q value = 0.12

Table S43.  Gene #15: '8p gain' versus Clinical Feature #1: 'Time to Death'

nPatients nDeath Duration Range (Median), Month
ALL 526 69 0.1 - 191.8 (23.3)
8P GAIN MUTATED 116 21 0.1 - 191.8 (20.0)
8P GAIN WILD-TYPE 410 48 0.1 - 185.8 (24.0)

Figure S43.  Get High-res Image Gene #15: '8p gain' versus Clinical Feature #1: 'Time to Death'

'8p gain' versus 'YEARS_TO_BIRTH'

P value = 0.0965 (Wilcoxon-test), Q value = 0.24

Table S44.  Gene #15: '8p gain' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

nPatients Mean (Std.Dev)
ALL 526 64.0 (11.2)
8P GAIN MUTATED 117 62.1 (12.9)
8P GAIN WILD-TYPE 409 64.5 (10.6)

Figure S44.  Get High-res Image Gene #15: '8p gain' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

'8p gain' versus 'RADIATIONS_RADIATION_REGIMENINDICATION'

P value = 0.0975 (Fisher's exact test), Q value = 0.24

Table S45.  Gene #15: '8p gain' versus Clinical Feature #4: 'RADIATIONS_RADIATION_REGIMENINDICATION'

nPatients NO YES
ALL 141 387
8P GAIN MUTATED 24 93
8P GAIN WILD-TYPE 117 294

Figure S45.  Get High-res Image Gene #15: '8p gain' versus Clinical Feature #4: 'RADIATIONS_RADIATION_REGIMENINDICATION'

'8q gain' versus 'Time to Death'

P value = 0.00211 (logrank test), Q value = 0.012

Table S46.  Gene #16: '8q gain' versus Clinical Feature #1: 'Time to Death'

nPatients nDeath Duration Range (Median), Month
ALL 526 69 0.1 - 191.8 (23.3)
8Q GAIN MUTATED 155 31 0.1 - 191.8 (20.6)
8Q GAIN WILD-TYPE 371 38 0.2 - 185.8 (24.0)

Figure S46.  Get High-res Image Gene #16: '8q gain' versus Clinical Feature #1: 'Time to Death'

'8q gain' versus 'HISTOLOGICAL_TYPE'

P value = 0.00276 (Fisher's exact test), Q value = 0.015

Table S47.  Gene #16: '8q gain' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 395 21 112
8Q GAIN MUTATED 102 8 47
8Q GAIN WILD-TYPE 293 13 65

Figure S47.  Get High-res Image Gene #16: '8q gain' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

'8q gain' versus 'RADIATIONS_RADIATION_REGIMENINDICATION'

P value = 0.0406 (Fisher's exact test), Q value = 0.12

Table S48.  Gene #16: '8q gain' versus Clinical Feature #4: 'RADIATIONS_RADIATION_REGIMENINDICATION'

nPatients NO YES
ALL 141 387
8Q GAIN MUTATED 32 125
8Q GAIN WILD-TYPE 109 262

Figure S48.  Get High-res Image Gene #16: '8q gain' versus Clinical Feature #4: 'RADIATIONS_RADIATION_REGIMENINDICATION'

'9p gain' versus 'ETHNICITY'

P value = 0.0139 (Fisher's exact test), Q value = 0.054

Table S49.  Gene #17: '9p gain' versus Clinical Feature #7: 'ETHNICITY'

nPatients HISPANIC OR LATINO NOT HISPANIC OR LATINO
ALL 14 367
9P GAIN MUTATED 3 12
9P GAIN WILD-TYPE 11 355

Figure S49.  Get High-res Image Gene #17: '9p gain' versus Clinical Feature #7: 'ETHNICITY'

'9q gain' versus 'COMPLETENESS_OF_RESECTION'

P value = 0.0754 (Fisher's exact test), Q value = 0.2

Table S50.  Gene #18: '9q gain' versus Clinical Feature #5: 'COMPLETENESS_OF_RESECTION'

nPatients R0 R1 R2 RX
ALL 363 23 17 35
9Q GAIN MUTATED 3 1 0 2
9Q GAIN WILD-TYPE 360 22 17 33

Figure S50.  Get High-res Image Gene #18: '9q gain' versus Clinical Feature #5: 'COMPLETENESS_OF_RESECTION'

'10p gain' versus 'YEARS_TO_BIRTH'

P value = 0.0944 (Wilcoxon-test), Q value = 0.24

Table S51.  Gene #19: '10p gain' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

nPatients Mean (Std.Dev)
ALL 526 64.0 (11.2)
10P GAIN MUTATED 115 65.4 (12.0)
10P GAIN WILD-TYPE 411 63.6 (11.0)

Figure S51.  Get High-res Image Gene #19: '10p gain' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

'11p gain' versus 'HISTOLOGICAL_TYPE'

P value = 2e-05 (Fisher's exact test), Q value = 0.00019

Table S52.  Gene #21: '11p gain' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 395 21 112
11P GAIN MUTATED 7 0 15
11P GAIN WILD-TYPE 388 21 97

Figure S52.  Get High-res Image Gene #21: '11p gain' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

'11q gain' versus 'Time to Death'

P value = 0.00447 (logrank test), Q value = 0.022

Table S53.  Gene #22: '11q gain' versus Clinical Feature #1: 'Time to Death'

nPatients nDeath Duration Range (Median), Month
ALL 526 69 0.1 - 191.8 (23.3)
11Q GAIN MUTATED 18 6 2.1 - 67.2 (20.6)
11Q GAIN WILD-TYPE 508 63 0.1 - 191.8 (23.4)

Figure S53.  Get High-res Image Gene #22: '11q gain' versus Clinical Feature #1: 'Time to Death'

'11q gain' versus 'HISTOLOGICAL_TYPE'

P value = 0.0179 (Fisher's exact test), Q value = 0.066

Table S54.  Gene #22: '11q gain' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 395 21 112
11Q GAIN MUTATED 9 0 9
11Q GAIN WILD-TYPE 386 21 103

Figure S54.  Get High-res Image Gene #22: '11q gain' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

'12p gain' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 9.9e-05

Table S55.  Gene #23: '12p gain' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 395 21 112
12P GAIN MUTATED 36 3 31
12P GAIN WILD-TYPE 359 18 81

Figure S55.  Get High-res Image Gene #23: '12p gain' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

'12p gain' versus 'RACE'

P value = 0.0605 (Fisher's exact test), Q value = 0.17

Table S56.  Gene #23: '12p gain' versus Clinical Feature #6: 'RACE'

nPatients AMERICAN INDIAN OR ALASKA NATIVE ASIAN BLACK OR AFRICAN AMERICAN NATIVE HAWAIIAN OR OTHER PACIFIC ISLANDER WHITE
ALL 4 20 101 9 366
12P GAIN MUTATED 0 6 18 2 42
12P GAIN WILD-TYPE 4 14 83 7 324

Figure S56.  Get High-res Image Gene #23: '12p gain' versus Clinical Feature #6: 'RACE'

'12q gain' versus 'Time to Death'

P value = 0.0636 (logrank test), Q value = 0.18

Table S57.  Gene #24: '12q gain' versus Clinical Feature #1: 'Time to Death'

nPatients nDeath Duration Range (Median), Month
ALL 526 69 0.1 - 191.8 (23.3)
12Q GAIN MUTATED 53 3 1.2 - 149.6 (27.3)
12Q GAIN WILD-TYPE 473 66 0.1 - 191.8 (22.8)

Figure S57.  Get High-res Image Gene #24: '12q gain' versus Clinical Feature #1: 'Time to Death'

'12q gain' versus 'HISTOLOGICAL_TYPE'

P value = 0.0366 (Fisher's exact test), Q value = 0.11

Table S58.  Gene #24: '12q gain' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 395 21 112
12Q GAIN MUTATED 32 3 18
12Q GAIN WILD-TYPE 363 18 94

Figure S58.  Get High-res Image Gene #24: '12q gain' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

'12q gain' versus 'RACE'

P value = 0.0876 (Fisher's exact test), Q value = 0.22

Table S59.  Gene #24: '12q gain' versus Clinical Feature #6: 'RACE'

nPatients AMERICAN INDIAN OR ALASKA NATIVE ASIAN BLACK OR AFRICAN AMERICAN NATIVE HAWAIIAN OR OTHER PACIFIC ISLANDER WHITE
ALL 4 20 101 9 366
12Q GAIN MUTATED 0 5 12 2 32
12Q GAIN WILD-TYPE 4 15 89 7 334

Figure S59.  Get High-res Image Gene #24: '12q gain' versus Clinical Feature #6: 'RACE'

'13q gain' versus 'YEARS_TO_BIRTH'

P value = 0.0118 (Wilcoxon-test), Q value = 0.047

Table S60.  Gene #25: '13q gain' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

nPatients Mean (Std.Dev)
ALL 526 64.0 (11.2)
13Q GAIN MUTATED 29 68.5 (6.4)
13Q GAIN WILD-TYPE 497 63.7 (11.4)

Figure S60.  Get High-res Image Gene #25: '13q gain' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

'13q gain' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 9.9e-05

Table S61.  Gene #25: '13q gain' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 395 21 112
13Q GAIN MUTATED 8 1 20
13Q GAIN WILD-TYPE 387 20 92

Figure S61.  Get High-res Image Gene #25: '13q gain' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

'14q gain' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 9.9e-05

Table S62.  Gene #26: '14q gain' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 395 21 112
14Q GAIN MUTATED 14 2 20
14Q GAIN WILD-TYPE 381 19 92

Figure S62.  Get High-res Image Gene #26: '14q gain' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

'14q gain' versus 'RADIATIONS_RADIATION_REGIMENINDICATION'

P value = 0.00993 (Fisher's exact test), Q value = 0.041

Table S63.  Gene #26: '14q gain' versus Clinical Feature #4: 'RADIATIONS_RADIATION_REGIMENINDICATION'

nPatients NO YES
ALL 141 387
14Q GAIN MUTATED 3 33
14Q GAIN WILD-TYPE 138 354

Figure S63.  Get High-res Image Gene #26: '14q gain' versus Clinical Feature #4: 'RADIATIONS_RADIATION_REGIMENINDICATION'

'15q gain' versus 'Time to Death'

P value = 0.0238 (logrank test), Q value = 0.081

Table S64.  Gene #27: '15q gain' versus Clinical Feature #1: 'Time to Death'

nPatients nDeath Duration Range (Median), Month
ALL 526 69 0.1 - 191.8 (23.3)
15Q GAIN MUTATED 10 3 4.4 - 75.7 (18.8)
15Q GAIN WILD-TYPE 516 66 0.1 - 191.8 (23.5)

Figure S64.  Get High-res Image Gene #27: '15q gain' versus Clinical Feature #1: 'Time to Death'

'16p gain' versus 'YEARS_TO_BIRTH'

P value = 0.0178 (Wilcoxon-test), Q value = 0.066

Table S65.  Gene #28: '16p gain' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

nPatients Mean (Std.Dev)
ALL 526 64.0 (11.2)
16P GAIN MUTATED 27 68.4 (8.8)
16P GAIN WILD-TYPE 499 63.8 (11.3)

Figure S65.  Get High-res Image Gene #28: '16p gain' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

'16p gain' versus 'HISTOLOGICAL_TYPE'

P value = 0.0428 (Fisher's exact test), Q value = 0.13

Table S66.  Gene #28: '16p gain' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 395 21 112
16P GAIN MUTATED 15 1 11
16P GAIN WILD-TYPE 380 20 101

Figure S66.  Get High-res Image Gene #28: '16p gain' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

'16p gain' versus 'RADIATIONS_RADIATION_REGIMENINDICATION'

P value = 0.0731 (Fisher's exact test), Q value = 0.2

Table S67.  Gene #28: '16p gain' versus Clinical Feature #4: 'RADIATIONS_RADIATION_REGIMENINDICATION'

nPatients NO YES
ALL 141 387
16P GAIN MUTATED 3 24
16P GAIN WILD-TYPE 138 363

Figure S67.  Get High-res Image Gene #28: '16p gain' versus Clinical Feature #4: 'RADIATIONS_RADIATION_REGIMENINDICATION'

'16p gain' versus 'RACE'

P value = 0.067 (Fisher's exact test), Q value = 0.18

Table S68.  Gene #28: '16p gain' versus Clinical Feature #6: 'RACE'

nPatients AMERICAN INDIAN OR ALASKA NATIVE ASIAN BLACK OR AFRICAN AMERICAN NATIVE HAWAIIAN OR OTHER PACIFIC ISLANDER WHITE
ALL 4 20 101 9 366
16P GAIN MUTATED 0 0 10 1 13
16P GAIN WILD-TYPE 4 20 91 8 353

Figure S68.  Get High-res Image Gene #28: '16p gain' versus Clinical Feature #6: 'RACE'

'16q gain' versus 'HISTOLOGICAL_TYPE'

P value = 0.0951 (Fisher's exact test), Q value = 0.24

Table S69.  Gene #29: '16q gain' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 395 21 112
16Q GAIN MUTATED 5 1 4
16Q GAIN WILD-TYPE 390 20 108

Figure S69.  Get High-res Image Gene #29: '16q gain' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

'16q gain' versus 'COMPLETENESS_OF_RESECTION'

P value = 0.00243 (Fisher's exact test), Q value = 0.013

Table S70.  Gene #29: '16q gain' versus Clinical Feature #5: 'COMPLETENESS_OF_RESECTION'

nPatients R0 R1 R2 RX
ALL 363 23 17 35
16Q GAIN MUTATED 3 3 0 2
16Q GAIN WILD-TYPE 360 20 17 33

Figure S70.  Get High-res Image Gene #29: '16q gain' versus Clinical Feature #5: 'COMPLETENESS_OF_RESECTION'

'17q gain' versus 'Time to Death'

P value = 0.00556 (logrank test), Q value = 0.026

Table S71.  Gene #31: '17q gain' versus Clinical Feature #1: 'Time to Death'

nPatients nDeath Duration Range (Median), Month
ALL 526 69 0.1 - 191.8 (23.3)
17Q GAIN MUTATED 30 7 0.1 - 76.8 (16.9)
17Q GAIN WILD-TYPE 496 62 0.1 - 191.8 (23.8)

Figure S71.  Get High-res Image Gene #31: '17q gain' versus Clinical Feature #1: 'Time to Death'

'17q gain' versus 'HISTOLOGICAL_TYPE'

P value = 3e-05 (Fisher's exact test), Q value = 0.00027

Table S72.  Gene #31: '17q gain' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 395 21 112
17Q GAIN MUTATED 13 0 17
17Q GAIN WILD-TYPE 382 21 95

Figure S72.  Get High-res Image Gene #31: '17q gain' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

'17q gain' versus 'COMPLETENESS_OF_RESECTION'

P value = 0.0245 (Fisher's exact test), Q value = 0.083

Table S73.  Gene #31: '17q gain' versus Clinical Feature #5: 'COMPLETENESS_OF_RESECTION'

nPatients R0 R1 R2 RX
ALL 363 23 17 35
17Q GAIN MUTATED 18 1 4 3
17Q GAIN WILD-TYPE 345 22 13 32

Figure S73.  Get High-res Image Gene #31: '17q gain' versus Clinical Feature #5: 'COMPLETENESS_OF_RESECTION'

'17q gain' versus 'RACE'

P value = 0.00803 (Fisher's exact test), Q value = 0.035

Table S74.  Gene #31: '17q gain' versus Clinical Feature #6: 'RACE'

nPatients AMERICAN INDIAN OR ALASKA NATIVE ASIAN BLACK OR AFRICAN AMERICAN NATIVE HAWAIIAN OR OTHER PACIFIC ISLANDER WHITE
ALL 4 20 101 9 366
17Q GAIN MUTATED 0 0 14 0 14
17Q GAIN WILD-TYPE 4 20 87 9 352

Figure S74.  Get High-res Image Gene #31: '17q gain' versus Clinical Feature #6: 'RACE'

'18p gain' versus 'Time to Death'

P value = 0.00618 (logrank test), Q value = 0.028

Table S75.  Gene #32: '18p gain' versus Clinical Feature #1: 'Time to Death'

nPatients nDeath Duration Range (Median), Month
ALL 526 69 0.1 - 191.8 (23.3)
18P GAIN MUTATED 71 17 0.4 - 125.4 (23.7)
18P GAIN WILD-TYPE 455 52 0.1 - 191.8 (23.3)

Figure S75.  Get High-res Image Gene #32: '18p gain' versus Clinical Feature #1: 'Time to Death'

'18p gain' versus 'YEARS_TO_BIRTH'

P value = 0.00132 (Wilcoxon-test), Q value = 0.0077

Table S76.  Gene #32: '18p gain' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

nPatients Mean (Std.Dev)
ALL 526 64.0 (11.2)
18P GAIN MUTATED 71 67.9 (10.1)
18P GAIN WILD-TYPE 455 63.4 (11.3)

Figure S76.  Get High-res Image Gene #32: '18p gain' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

'18p gain' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 9.9e-05

Table S77.  Gene #32: '18p gain' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 395 21 112
18P GAIN MUTATED 21 5 45
18P GAIN WILD-TYPE 374 16 67

Figure S77.  Get High-res Image Gene #32: '18p gain' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

'18p gain' versus 'COMPLETENESS_OF_RESECTION'

P value = 0.0246 (Fisher's exact test), Q value = 0.083

Table S78.  Gene #32: '18p gain' versus Clinical Feature #5: 'COMPLETENESS_OF_RESECTION'

nPatients R0 R1 R2 RX
ALL 363 23 17 35
18P GAIN MUTATED 46 1 6 7
18P GAIN WILD-TYPE 317 22 11 28

Figure S78.  Get High-res Image Gene #32: '18p gain' versus Clinical Feature #5: 'COMPLETENESS_OF_RESECTION'

'18p gain' versus 'RACE'

P value = 0.00044 (Fisher's exact test), Q value = 0.0031

Table S79.  Gene #32: '18p gain' versus Clinical Feature #6: 'RACE'

nPatients AMERICAN INDIAN OR ALASKA NATIVE ASIAN BLACK OR AFRICAN AMERICAN NATIVE HAWAIIAN OR OTHER PACIFIC ISLANDER WHITE
ALL 4 20 101 9 366
18P GAIN MUTATED 0 2 28 1 36
18P GAIN WILD-TYPE 4 18 73 8 330

Figure S79.  Get High-res Image Gene #32: '18p gain' versus Clinical Feature #6: 'RACE'

'18q gain' versus 'Time to Death'

P value = 9.16e-05 (logrank test), Q value = 7e-04

Table S80.  Gene #33: '18q gain' versus Clinical Feature #1: 'Time to Death'

nPatients nDeath Duration Range (Median), Month
ALL 526 69 0.1 - 191.8 (23.3)
18Q GAIN MUTATED 44 14 2.4 - 125.4 (23.0)
18Q GAIN WILD-TYPE 482 55 0.1 - 191.8 (23.3)

Figure S80.  Get High-res Image Gene #33: '18q gain' versus Clinical Feature #1: 'Time to Death'

'18q gain' versus 'YEARS_TO_BIRTH'

P value = 0.015 (Wilcoxon-test), Q value = 0.058

Table S81.  Gene #33: '18q gain' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

nPatients Mean (Std.Dev)
ALL 526 64.0 (11.2)
18Q GAIN MUTATED 44 68.0 (11.2)
18Q GAIN WILD-TYPE 482 63.6 (11.2)

Figure S81.  Get High-res Image Gene #33: '18q gain' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

'18q gain' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 9.9e-05

Table S82.  Gene #33: '18q gain' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 395 21 112
18Q GAIN MUTATED 16 4 24
18Q GAIN WILD-TYPE 379 17 88

Figure S82.  Get High-res Image Gene #33: '18q gain' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

'18q gain' versus 'COMPLETENESS_OF_RESECTION'

P value = 0.0134 (Fisher's exact test), Q value = 0.053

Table S83.  Gene #33: '18q gain' versus Clinical Feature #5: 'COMPLETENESS_OF_RESECTION'

nPatients R0 R1 R2 RX
ALL 363 23 17 35
18Q GAIN MUTATED 27 0 4 6
18Q GAIN WILD-TYPE 336 23 13 29

Figure S83.  Get High-res Image Gene #33: '18q gain' versus Clinical Feature #5: 'COMPLETENESS_OF_RESECTION'

'19p gain' versus 'YEARS_TO_BIRTH'

P value = 1.83e-06 (Wilcoxon-test), Q value = 9.9e-05

Table S84.  Gene #34: '19p gain' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

nPatients Mean (Std.Dev)
ALL 526 64.0 (11.2)
19P GAIN MUTATED 52 70.5 (8.6)
19P GAIN WILD-TYPE 474 63.3 (11.2)

Figure S84.  Get High-res Image Gene #34: '19p gain' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

'19p gain' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 9.9e-05

Table S85.  Gene #34: '19p gain' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 395 21 112
19P GAIN MUTATED 20 3 29
19P GAIN WILD-TYPE 375 18 83

Figure S85.  Get High-res Image Gene #34: '19p gain' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

'19q gain' versus 'Time to Death'

P value = 0.0196 (logrank test), Q value = 0.071

Table S86.  Gene #35: '19q gain' versus Clinical Feature #1: 'Time to Death'

nPatients nDeath Duration Range (Median), Month
ALL 526 69 0.1 - 191.8 (23.3)
19Q GAIN MUTATED 54 12 0.1 - 110.1 (21.4)
19Q GAIN WILD-TYPE 472 57 0.2 - 191.8 (23.6)

Figure S86.  Get High-res Image Gene #35: '19q gain' versus Clinical Feature #1: 'Time to Death'

'19q gain' versus 'YEARS_TO_BIRTH'

P value = 1.72e-07 (Wilcoxon-test), Q value = 4.9e-05

Table S87.  Gene #35: '19q gain' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

nPatients Mean (Std.Dev)
ALL 526 64.0 (11.2)
19Q GAIN MUTATED 55 70.9 (8.6)
19Q GAIN WILD-TYPE 471 63.2 (11.2)

Figure S87.  Get High-res Image Gene #35: '19q gain' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

'19q gain' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 9.9e-05

Table S88.  Gene #35: '19q gain' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 395 21 112
19Q GAIN MUTATED 15 3 37
19Q GAIN WILD-TYPE 380 18 75

Figure S88.  Get High-res Image Gene #35: '19q gain' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

'19q gain' versus 'RACE'

P value = 0.0222 (Fisher's exact test), Q value = 0.077

Table S89.  Gene #35: '19q gain' versus Clinical Feature #6: 'RACE'

nPatients AMERICAN INDIAN OR ALASKA NATIVE ASIAN BLACK OR AFRICAN AMERICAN NATIVE HAWAIIAN OR OTHER PACIFIC ISLANDER WHITE
ALL 4 20 101 9 366
19Q GAIN MUTATED 0 2 20 0 30
19Q GAIN WILD-TYPE 4 18 81 9 336

Figure S89.  Get High-res Image Gene #35: '19q gain' versus Clinical Feature #6: 'RACE'

'20p gain' versus 'Time to Death'

P value = 0.00803 (logrank test), Q value = 0.035

Table S90.  Gene #36: '20p gain' versus Clinical Feature #1: 'Time to Death'

nPatients nDeath Duration Range (Median), Month
ALL 526 69 0.1 - 191.8 (23.3)
20P GAIN MUTATED 110 21 0.1 - 125.4 (19.5)
20P GAIN WILD-TYPE 416 48 0.1 - 191.8 (23.8)

Figure S90.  Get High-res Image Gene #36: '20p gain' versus Clinical Feature #1: 'Time to Death'

'20p gain' versus 'YEARS_TO_BIRTH'

P value = 5.83e-05 (Wilcoxon-test), Q value = 0.00049

Table S91.  Gene #36: '20p gain' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

nPatients Mean (Std.Dev)
ALL 526 64.0 (11.2)
20P GAIN MUTATED 110 67.6 (10.0)
20P GAIN WILD-TYPE 416 63.1 (11.3)

Figure S91.  Get High-res Image Gene #36: '20p gain' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

'20p gain' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 9.9e-05

Table S92.  Gene #36: '20p gain' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 395 21 112
20P GAIN MUTATED 46 4 60
20P GAIN WILD-TYPE 349 17 52

Figure S92.  Get High-res Image Gene #36: '20p gain' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

'20p gain' versus 'RADIATIONS_RADIATION_REGIMENINDICATION'

P value = 0.00101 (Fisher's exact test), Q value = 0.0062

Table S93.  Gene #36: '20p gain' versus Clinical Feature #4: 'RADIATIONS_RADIATION_REGIMENINDICATION'

nPatients NO YES
ALL 141 387
20P GAIN MUTATED 16 94
20P GAIN WILD-TYPE 125 293

Figure S93.  Get High-res Image Gene #36: '20p gain' versus Clinical Feature #4: 'RADIATIONS_RADIATION_REGIMENINDICATION'

'20p gain' versus 'COMPLETENESS_OF_RESECTION'

P value = 0.0674 (Fisher's exact test), Q value = 0.18

Table S94.  Gene #36: '20p gain' versus Clinical Feature #5: 'COMPLETENESS_OF_RESECTION'

nPatients R0 R1 R2 RX
ALL 363 23 17 35
20P GAIN MUTATED 66 4 7 10
20P GAIN WILD-TYPE 297 19 10 25

Figure S94.  Get High-res Image Gene #36: '20p gain' versus Clinical Feature #5: 'COMPLETENESS_OF_RESECTION'

'20p gain' versus 'RACE'

P value = 0.0835 (Fisher's exact test), Q value = 0.22

Table S95.  Gene #36: '20p gain' versus Clinical Feature #6: 'RACE'

nPatients AMERICAN INDIAN OR ALASKA NATIVE ASIAN BLACK OR AFRICAN AMERICAN NATIVE HAWAIIAN OR OTHER PACIFIC ISLANDER WHITE
ALL 4 20 101 9 366
20P GAIN MUTATED 1 4 30 2 64
20P GAIN WILD-TYPE 3 16 71 7 302

Figure S95.  Get High-res Image Gene #36: '20p gain' versus Clinical Feature #6: 'RACE'

'20q gain' versus 'Time to Death'

P value = 0.00116 (logrank test), Q value = 0.007

Table S96.  Gene #37: '20q gain' versus Clinical Feature #1: 'Time to Death'

nPatients nDeath Duration Range (Median), Month
ALL 526 69 0.1 - 191.8 (23.3)
20Q GAIN MUTATED 129 27 0.1 - 191.8 (20.1)
20Q GAIN WILD-TYPE 397 42 0.1 - 185.8 (23.9)

Figure S96.  Get High-res Image Gene #37: '20q gain' versus Clinical Feature #1: 'Time to Death'

'20q gain' versus 'YEARS_TO_BIRTH'

P value = 4.45e-06 (Wilcoxon-test), Q value = 9.9e-05

Table S97.  Gene #37: '20q gain' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

nPatients Mean (Std.Dev)
ALL 526 64.0 (11.2)
20Q GAIN MUTATED 129 67.7 (9.9)
20Q GAIN WILD-TYPE 397 62.8 (11.4)

Figure S97.  Get High-res Image Gene #37: '20q gain' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

'20q gain' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 9.9e-05

Table S98.  Gene #37: '20q gain' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 395 21 112
20Q GAIN MUTATED 56 4 70
20Q GAIN WILD-TYPE 339 17 42

Figure S98.  Get High-res Image Gene #37: '20q gain' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

'20q gain' versus 'RADIATIONS_RADIATION_REGIMENINDICATION'

P value = 6e-04 (Fisher's exact test), Q value = 0.004

Table S99.  Gene #37: '20q gain' versus Clinical Feature #4: 'RADIATIONS_RADIATION_REGIMENINDICATION'

nPatients NO YES
ALL 141 387
20Q GAIN MUTATED 20 110
20Q GAIN WILD-TYPE 121 277

Figure S99.  Get High-res Image Gene #37: '20q gain' versus Clinical Feature #4: 'RADIATIONS_RADIATION_REGIMENINDICATION'

'20q gain' versus 'COMPLETENESS_OF_RESECTION'

P value = 0.0171 (Fisher's exact test), Q value = 0.064

Table S100.  Gene #37: '20q gain' versus Clinical Feature #5: 'COMPLETENESS_OF_RESECTION'

nPatients R0 R1 R2 RX
ALL 363 23 17 35
20Q GAIN MUTATED 76 5 9 11
20Q GAIN WILD-TYPE 287 18 8 24

Figure S100.  Get High-res Image Gene #37: '20q gain' versus Clinical Feature #5: 'COMPLETENESS_OF_RESECTION'

'20q gain' versus 'RACE'

P value = 0.00774 (Fisher's exact test), Q value = 0.034

Table S101.  Gene #37: '20q gain' versus Clinical Feature #6: 'RACE'

nPatients AMERICAN INDIAN OR ALASKA NATIVE ASIAN BLACK OR AFRICAN AMERICAN NATIVE HAWAIIAN OR OTHER PACIFIC ISLANDER WHITE
ALL 4 20 101 9 366
20Q GAIN MUTATED 1 4 38 3 75
20Q GAIN WILD-TYPE 3 16 63 6 291

Figure S101.  Get High-res Image Gene #37: '20q gain' versus Clinical Feature #6: 'RACE'

'21q gain' versus 'Time to Death'

P value = 0.0261 (logrank test), Q value = 0.086

Table S102.  Gene #38: '21q gain' versus Clinical Feature #1: 'Time to Death'

nPatients nDeath Duration Range (Median), Month
ALL 526 69 0.1 - 191.8 (23.3)
21Q GAIN MUTATED 38 9 0.1 - 110.1 (21.0)
21Q GAIN WILD-TYPE 488 60 0.1 - 191.8 (23.4)

Figure S102.  Get High-res Image Gene #38: '21q gain' versus Clinical Feature #1: 'Time to Death'

'21q gain' versus 'YEARS_TO_BIRTH'

P value = 0.000956 (Wilcoxon-test), Q value = 0.006

Table S103.  Gene #38: '21q gain' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

nPatients Mean (Std.Dev)
ALL 526 64.0 (11.2)
21Q GAIN MUTATED 38 69.6 (9.1)
21Q GAIN WILD-TYPE 488 63.6 (11.3)

Figure S103.  Get High-res Image Gene #38: '21q gain' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

'21q gain' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 9.9e-05

Table S104.  Gene #38: '21q gain' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 395 21 112
21Q GAIN MUTATED 12 1 25
21Q GAIN WILD-TYPE 383 20 87

Figure S104.  Get High-res Image Gene #38: '21q gain' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

'22q gain' versus 'YEARS_TO_BIRTH'

P value = 0.00321 (Wilcoxon-test), Q value = 0.017

Table S105.  Gene #39: '22q gain' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

nPatients Mean (Std.Dev)
ALL 526 64.0 (11.2)
22Q GAIN MUTATED 30 69.6 (8.3)
22Q GAIN WILD-TYPE 496 63.7 (11.3)

Figure S105.  Get High-res Image Gene #39: '22q gain' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

'22q gain' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 9.9e-05

Table S106.  Gene #39: '22q gain' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 395 21 112
22Q GAIN MUTATED 7 1 23
22Q GAIN WILD-TYPE 388 20 89

Figure S106.  Get High-res Image Gene #39: '22q gain' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

'22q gain' versus 'COMPLETENESS_OF_RESECTION'

P value = 0.0336 (Fisher's exact test), Q value = 0.11

Table S107.  Gene #39: '22q gain' versus Clinical Feature #5: 'COMPLETENESS_OF_RESECTION'

nPatients R0 R1 R2 RX
ALL 363 23 17 35
22Q GAIN MUTATED 19 1 4 3
22Q GAIN WILD-TYPE 344 22 13 32

Figure S107.  Get High-res Image Gene #39: '22q gain' versus Clinical Feature #5: 'COMPLETENESS_OF_RESECTION'

'xq gain' versus 'Time to Death'

P value = 0.00863 (logrank test), Q value = 0.036

Table S108.  Gene #41: 'xq gain' versus Clinical Feature #1: 'Time to Death'

nPatients nDeath Duration Range (Median), Month
ALL 526 69 0.1 - 191.8 (23.3)
XQ GAIN MUTATED 63 14 0.1 - 81.4 (22.3)
XQ GAIN WILD-TYPE 463 55 0.2 - 191.8 (23.5)

Figure S108.  Get High-res Image Gene #41: 'xq gain' versus Clinical Feature #1: 'Time to Death'

'1p loss' versus 'YEARS_TO_BIRTH'

P value = 0.0382 (Wilcoxon-test), Q value = 0.12

Table S109.  Gene #42: '1p loss' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

nPatients Mean (Std.Dev)
ALL 526 64.0 (11.2)
1P LOSS MUTATED 25 69.1 (10.2)
1P LOSS WILD-TYPE 501 63.8 (11.2)

Figure S109.  Get High-res Image Gene #42: '1p loss' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

'1p loss' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 9.9e-05

Table S110.  Gene #42: '1p loss' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 395 21 112
1P LOSS MUTATED 6 3 16
1P LOSS WILD-TYPE 389 18 96

Figure S110.  Get High-res Image Gene #42: '1p loss' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

'1p loss' versus 'COMPLETENESS_OF_RESECTION'

P value = 0.00279 (Fisher's exact test), Q value = 0.015

Table S111.  Gene #42: '1p loss' versus Clinical Feature #5: 'COMPLETENESS_OF_RESECTION'

nPatients R0 R1 R2 RX
ALL 363 23 17 35
1P LOSS MUTATED 15 3 4 0
1P LOSS WILD-TYPE 348 20 13 35

Figure S111.  Get High-res Image Gene #42: '1p loss' versus Clinical Feature #5: 'COMPLETENESS_OF_RESECTION'

'1q loss' versus 'HISTOLOGICAL_TYPE'

P value = 7e-05 (Fisher's exact test), Q value = 0.00057

Table S112.  Gene #43: '1q loss' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 395 21 112
1Q LOSS MUTATED 3 2 9
1Q LOSS WILD-TYPE 392 19 103

Figure S112.  Get High-res Image Gene #43: '1q loss' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

'1q loss' versus 'COMPLETENESS_OF_RESECTION'

P value = 0.0192 (Fisher's exact test), Q value = 0.07

Table S113.  Gene #43: '1q loss' versus Clinical Feature #5: 'COMPLETENESS_OF_RESECTION'

nPatients R0 R1 R2 RX
ALL 363 23 17 35
1Q LOSS MUTATED 9 1 3 0
1Q LOSS WILD-TYPE 354 22 14 35

Figure S113.  Get High-res Image Gene #43: '1q loss' versus Clinical Feature #5: 'COMPLETENESS_OF_RESECTION'

'2p loss' versus 'Time to Death'

P value = 0.0774 (logrank test), Q value = 0.2

Table S114.  Gene #44: '2p loss' versus Clinical Feature #1: 'Time to Death'

nPatients nDeath Duration Range (Median), Month
ALL 526 69 0.1 - 191.8 (23.3)
2P LOSS MUTATED 11 3 0.6 - 67.2 (22.3)
2P LOSS WILD-TYPE 515 66 0.1 - 191.8 (23.3)

Figure S114.  Get High-res Image Gene #44: '2p loss' versus Clinical Feature #1: 'Time to Death'

'2q loss' versus 'Time to Death'

P value = 0.0104 (logrank test), Q value = 0.042

Table S115.  Gene #45: '2q loss' versus Clinical Feature #1: 'Time to Death'

nPatients nDeath Duration Range (Median), Month
ALL 526 69 0.1 - 191.8 (23.3)
2Q LOSS MUTATED 17 5 0.6 - 67.2 (20.5)
2Q LOSS WILD-TYPE 509 64 0.1 - 191.8 (23.4)

Figure S115.  Get High-res Image Gene #45: '2q loss' versus Clinical Feature #1: 'Time to Death'

'3p loss' versus 'YEARS_TO_BIRTH'

P value = 0.00589 (Wilcoxon-test), Q value = 0.027

Table S116.  Gene #46: '3p loss' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

nPatients Mean (Std.Dev)
ALL 526 64.0 (11.2)
3P LOSS MUTATED 49 67.7 (8.2)
3P LOSS WILD-TYPE 477 63.6 (11.4)

Figure S116.  Get High-res Image Gene #46: '3p loss' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

'3p loss' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 9.9e-05

Table S117.  Gene #46: '3p loss' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 395 21 112
3P LOSS MUTATED 18 6 26
3P LOSS WILD-TYPE 377 15 86

Figure S117.  Get High-res Image Gene #46: '3p loss' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

'3q loss' versus 'YEARS_TO_BIRTH'

P value = 0.0553 (Wilcoxon-test), Q value = 0.16

Table S118.  Gene #47: '3q loss' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

nPatients Mean (Std.Dev)
ALL 526 64.0 (11.2)
3Q LOSS MUTATED 29 67.4 (9.1)
3Q LOSS WILD-TYPE 497 63.8 (11.3)

Figure S118.  Get High-res Image Gene #47: '3q loss' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

'3q loss' versus 'HISTOLOGICAL_TYPE'

P value = 3e-05 (Fisher's exact test), Q value = 0.00027

Table S119.  Gene #47: '3q loss' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 395 21 112
3Q LOSS MUTATED 11 2 17
3Q LOSS WILD-TYPE 384 19 95

Figure S119.  Get High-res Image Gene #47: '3q loss' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

'4p loss' versus 'Time to Death'

P value = 0.00128 (logrank test), Q value = 0.0076

Table S120.  Gene #48: '4p loss' versus Clinical Feature #1: 'Time to Death'

nPatients nDeath Duration Range (Median), Month
ALL 526 69 0.1 - 191.8 (23.3)
4P LOSS MUTATED 99 22 0.2 - 149.6 (20.3)
4P LOSS WILD-TYPE 427 47 0.1 - 191.8 (23.7)

Figure S120.  Get High-res Image Gene #48: '4p loss' versus Clinical Feature #1: 'Time to Death'

'4p loss' versus 'YEARS_TO_BIRTH'

P value = 7.21e-05 (Wilcoxon-test), Q value = 0.00058

Table S121.  Gene #48: '4p loss' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

nPatients Mean (Std.Dev)
ALL 526 64.0 (11.2)
4P LOSS MUTATED 100 68.0 (9.4)
4P LOSS WILD-TYPE 426 63.1 (11.4)

Figure S121.  Get High-res Image Gene #48: '4p loss' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

'4p loss' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 9.9e-05

Table S122.  Gene #48: '4p loss' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 395 21 112
4P LOSS MUTATED 31 6 63
4P LOSS WILD-TYPE 364 15 49

Figure S122.  Get High-res Image Gene #48: '4p loss' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

'4p loss' versus 'RADIATIONS_RADIATION_REGIMENINDICATION'

P value = 0.0325 (Fisher's exact test), Q value = 0.1

Table S123.  Gene #48: '4p loss' versus Clinical Feature #4: 'RADIATIONS_RADIATION_REGIMENINDICATION'

nPatients NO YES
ALL 141 387
4P LOSS MUTATED 18 82
4P LOSS WILD-TYPE 123 305

Figure S123.  Get High-res Image Gene #48: '4p loss' versus Clinical Feature #4: 'RADIATIONS_RADIATION_REGIMENINDICATION'

'4q loss' versus 'Time to Death'

P value = 0.00145 (logrank test), Q value = 0.0082

Table S124.  Gene #49: '4q loss' versus Clinical Feature #1: 'Time to Death'

nPatients nDeath Duration Range (Median), Month
ALL 526 69 0.1 - 191.8 (23.3)
4Q LOSS MUTATED 100 22 0.2 - 149.6 (20.9)
4Q LOSS WILD-TYPE 426 47 0.1 - 191.8 (23.6)

Figure S124.  Get High-res Image Gene #49: '4q loss' versus Clinical Feature #1: 'Time to Death'

'4q loss' versus 'YEARS_TO_BIRTH'

P value = 4.72e-05 (Wilcoxon-test), Q value = 0.00041

Table S125.  Gene #49: '4q loss' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

nPatients Mean (Std.Dev)
ALL 526 64.0 (11.2)
4Q LOSS MUTATED 101 67.9 (9.5)
4Q LOSS WILD-TYPE 425 63.1 (11.4)

Figure S125.  Get High-res Image Gene #49: '4q loss' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

'4q loss' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 9.9e-05

Table S126.  Gene #49: '4q loss' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 395 21 112
4Q LOSS MUTATED 32 7 62
4Q LOSS WILD-TYPE 363 14 50

Figure S126.  Get High-res Image Gene #49: '4q loss' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

'4q loss' versus 'RADIATIONS_RADIATION_REGIMENINDICATION'

P value = 0.0247 (Fisher's exact test), Q value = 0.083

Table S127.  Gene #49: '4q loss' versus Clinical Feature #4: 'RADIATIONS_RADIATION_REGIMENINDICATION'

nPatients NO YES
ALL 141 387
4Q LOSS MUTATED 18 83
4Q LOSS WILD-TYPE 123 304

Figure S127.  Get High-res Image Gene #49: '4q loss' versus Clinical Feature #4: 'RADIATIONS_RADIATION_REGIMENINDICATION'

'5p loss' versus 'Time to Death'

P value = 0.0281 (logrank test), Q value = 0.092

Table S128.  Gene #50: '5p loss' versus Clinical Feature #1: 'Time to Death'

nPatients nDeath Duration Range (Median), Month
ALL 526 69 0.1 - 191.8 (23.3)
5P LOSS MUTATED 54 12 0.2 - 149.6 (19.1)
5P LOSS WILD-TYPE 472 57 0.1 - 191.8 (23.7)

Figure S128.  Get High-res Image Gene #50: '5p loss' versus Clinical Feature #1: 'Time to Death'

'5p loss' versus 'YEARS_TO_BIRTH'

P value = 0.0861 (Wilcoxon-test), Q value = 0.22

Table S129.  Gene #50: '5p loss' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

nPatients Mean (Std.Dev)
ALL 526 64.0 (11.2)
5P LOSS MUTATED 54 65.9 (10.1)
5P LOSS WILD-TYPE 472 63.8 (11.3)

Figure S129.  Get High-res Image Gene #50: '5p loss' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

'5p loss' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 9.9e-05

Table S130.  Gene #50: '5p loss' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 395 21 112
5P LOSS MUTATED 16 1 37
5P LOSS WILD-TYPE 379 20 75

Figure S130.  Get High-res Image Gene #50: '5p loss' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

'5q loss' versus 'Time to Death'

P value = 0.00538 (logrank test), Q value = 0.026

Table S131.  Gene #51: '5q loss' versus Clinical Feature #1: 'Time to Death'

nPatients nDeath Duration Range (Median), Month
ALL 526 69 0.1 - 191.8 (23.3)
5Q LOSS MUTATED 73 17 0.2 - 149.6 (20.0)
5Q LOSS WILD-TYPE 453 52 0.1 - 191.8 (23.7)

Figure S131.  Get High-res Image Gene #51: '5q loss' versus Clinical Feature #1: 'Time to Death'

'5q loss' versus 'YEARS_TO_BIRTH'

P value = 0.000677 (Wilcoxon-test), Q value = 0.0045

Table S132.  Gene #51: '5q loss' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

nPatients Mean (Std.Dev)
ALL 526 64.0 (11.2)
5Q LOSS MUTATED 73 67.6 (9.8)
5Q LOSS WILD-TYPE 453 63.4 (11.3)

Figure S132.  Get High-res Image Gene #51: '5q loss' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

'5q loss' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 9.9e-05

Table S133.  Gene #51: '5q loss' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 395 21 112
5Q LOSS MUTATED 19 4 50
5Q LOSS WILD-TYPE 376 17 62

Figure S133.  Get High-res Image Gene #51: '5q loss' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

'6p loss' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 9.9e-05

Table S134.  Gene #52: '6p loss' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 395 21 112
6P LOSS MUTATED 4 1 12
6P LOSS WILD-TYPE 391 20 100

Figure S134.  Get High-res Image Gene #52: '6p loss' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

'6q loss' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 9.9e-05

Table S135.  Gene #53: '6q loss' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 395 21 112
6Q LOSS MUTATED 5 1 19
6Q LOSS WILD-TYPE 390 20 93

Figure S135.  Get High-res Image Gene #53: '6q loss' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

'7p loss' versus 'Time to Death'

P value = 0.0457 (logrank test), Q value = 0.14

Table S136.  Gene #54: '7p loss' versus Clinical Feature #1: 'Time to Death'

nPatients nDeath Duration Range (Median), Month
ALL 526 69 0.1 - 191.8 (23.3)
7P LOSS MUTATED 43 10 1.2 - 110.1 (23.2)
7P LOSS WILD-TYPE 483 59 0.1 - 191.8 (23.4)

Figure S136.  Get High-res Image Gene #54: '7p loss' versus Clinical Feature #1: 'Time to Death'

'7p loss' versus 'YEARS_TO_BIRTH'

P value = 4.87e-05 (Wilcoxon-test), Q value = 0.00042

Table S137.  Gene #54: '7p loss' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

nPatients Mean (Std.Dev)
ALL 526 64.0 (11.2)
7P LOSS MUTATED 43 70.0 (9.5)
7P LOSS WILD-TYPE 483 63.5 (11.2)

Figure S137.  Get High-res Image Gene #54: '7p loss' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

'7p loss' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 9.9e-05

Table S138.  Gene #54: '7p loss' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 395 21 112
7P LOSS MUTATED 14 2 27
7P LOSS WILD-TYPE 381 19 85

Figure S138.  Get High-res Image Gene #54: '7p loss' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

'7q loss' versus 'YEARS_TO_BIRTH'

P value = 0.0013 (Wilcoxon-test), Q value = 0.0076

Table S139.  Gene #55: '7q loss' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

nPatients Mean (Std.Dev)
ALL 526 64.0 (11.2)
7Q LOSS MUTATED 41 68.8 (7.1)
7Q LOSS WILD-TYPE 485 63.6 (11.4)

Figure S139.  Get High-res Image Gene #55: '7q loss' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

'7q loss' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 9.9e-05

Table S140.  Gene #55: '7q loss' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 395 21 112
7Q LOSS MUTATED 8 2 31
7Q LOSS WILD-TYPE 387 19 81

Figure S140.  Get High-res Image Gene #55: '7q loss' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

'8p loss' versus 'YEARS_TO_BIRTH'

P value = 4.75e-05 (Wilcoxon-test), Q value = 0.00041

Table S141.  Gene #56: '8p loss' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

nPatients Mean (Std.Dev)
ALL 526 64.0 (11.2)
8P LOSS MUTATED 77 68.2 (8.5)
8P LOSS WILD-TYPE 449 63.3 (11.5)

Figure S141.  Get High-res Image Gene #56: '8p loss' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

'8p loss' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 9.9e-05

Table S142.  Gene #56: '8p loss' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 395 21 112
8P LOSS MUTATED 17 4 57
8P LOSS WILD-TYPE 378 17 55

Figure S142.  Get High-res Image Gene #56: '8p loss' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

'8p loss' versus 'RACE'

P value = 0.0333 (Fisher's exact test), Q value = 0.11

Table S143.  Gene #56: '8p loss' versus Clinical Feature #6: 'RACE'

nPatients AMERICAN INDIAN OR ALASKA NATIVE ASIAN BLACK OR AFRICAN AMERICAN NATIVE HAWAIIAN OR OTHER PACIFIC ISLANDER WHITE
ALL 4 20 101 9 366
8P LOSS MUTATED 1 1 24 0 48
8P LOSS WILD-TYPE 3 19 77 9 318

Figure S143.  Get High-res Image Gene #56: '8p loss' versus Clinical Feature #6: 'RACE'

'8q loss' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 9.9e-05

Table S144.  Gene #57: '8q loss' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 395 21 112
8Q LOSS MUTATED 2 1 21
8Q LOSS WILD-TYPE 393 20 91

Figure S144.  Get High-res Image Gene #57: '8q loss' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

'9p loss' versus 'Time to Death'

P value = 0.00052 (logrank test), Q value = 0.0036

Table S145.  Gene #58: '9p loss' versus Clinical Feature #1: 'Time to Death'

nPatients nDeath Duration Range (Median), Month
ALL 526 69 0.1 - 191.8 (23.3)
9P LOSS MUTATED 101 25 0.3 - 149.6 (22.3)
9P LOSS WILD-TYPE 425 44 0.1 - 191.8 (23.5)

Figure S145.  Get High-res Image Gene #58: '9p loss' versus Clinical Feature #1: 'Time to Death'

'9p loss' versus 'YEARS_TO_BIRTH'

P value = 1.06e-05 (Wilcoxon-test), Q value = 1e-04

Table S146.  Gene #58: '9p loss' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

nPatients Mean (Std.Dev)
ALL 526 64.0 (11.2)
9P LOSS MUTATED 101 68.0 (8.5)
9P LOSS WILD-TYPE 425 63.0 (11.6)

Figure S146.  Get High-res Image Gene #58: '9p loss' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

'9p loss' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 9.9e-05

Table S147.  Gene #58: '9p loss' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 395 21 112
9P LOSS MUTATED 35 8 58
9P LOSS WILD-TYPE 360 13 54

Figure S147.  Get High-res Image Gene #58: '9p loss' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

'9p loss' versus 'COMPLETENESS_OF_RESECTION'

P value = 0.0618 (Fisher's exact test), Q value = 0.17

Table S148.  Gene #58: '9p loss' versus Clinical Feature #5: 'COMPLETENESS_OF_RESECTION'

nPatients R0 R1 R2 RX
ALL 363 23 17 35
9P LOSS MUTATED 62 5 7 9
9P LOSS WILD-TYPE 301 18 10 26

Figure S148.  Get High-res Image Gene #58: '9p loss' versus Clinical Feature #5: 'COMPLETENESS_OF_RESECTION'

'9q loss' versus 'Time to Death'

P value = 0.000927 (logrank test), Q value = 0.0059

Table S149.  Gene #59: '9q loss' versus Clinical Feature #1: 'Time to Death'

nPatients nDeath Duration Range (Median), Month
ALL 526 69 0.1 - 191.8 (23.3)
9Q LOSS MUTATED 120 27 0.2 - 125.4 (22.4)
9Q LOSS WILD-TYPE 406 42 0.1 - 191.8 (23.4)

Figure S149.  Get High-res Image Gene #59: '9q loss' versus Clinical Feature #1: 'Time to Death'

'9q loss' versus 'YEARS_TO_BIRTH'

P value = 4.51e-09 (Wilcoxon-test), Q value = 2.6e-06

Table S150.  Gene #59: '9q loss' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

nPatients Mean (Std.Dev)
ALL 526 64.0 (11.2)
9Q LOSS MUTATED 119 69.0 (8.8)
9Q LOSS WILD-TYPE 407 62.5 (11.4)

Figure S150.  Get High-res Image Gene #59: '9q loss' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

'9q loss' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 9.9e-05

Table S151.  Gene #59: '9q loss' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 395 21 112
9Q LOSS MUTATED 48 9 63
9Q LOSS WILD-TYPE 347 12 49

Figure S151.  Get High-res Image Gene #59: '9q loss' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

'10p loss' versus 'Time to Death'

P value = 0.0283 (logrank test), Q value = 0.092

Table S152.  Gene #60: '10p loss' versus Clinical Feature #1: 'Time to Death'

nPatients nDeath Duration Range (Median), Month
ALL 526 69 0.1 - 191.8 (23.3)
10P LOSS MUTATED 42 10 0.3 - 125.4 (22.9)
10P LOSS WILD-TYPE 484 59 0.1 - 191.8 (23.3)

Figure S152.  Get High-res Image Gene #60: '10p loss' versus Clinical Feature #1: 'Time to Death'

'10p loss' versus 'YEARS_TO_BIRTH'

P value = 0.0152 (Wilcoxon-test), Q value = 0.058

Table S153.  Gene #60: '10p loss' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

nPatients Mean (Std.Dev)
ALL 526 64.0 (11.2)
10P LOSS MUTATED 42 68.1 (8.6)
10P LOSS WILD-TYPE 484 63.7 (11.4)

Figure S153.  Get High-res Image Gene #60: '10p loss' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

'10p loss' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 9.9e-05

Table S154.  Gene #60: '10p loss' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 395 21 112
10P LOSS MUTATED 9 4 29
10P LOSS WILD-TYPE 386 17 83

Figure S154.  Get High-res Image Gene #60: '10p loss' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

'10p loss' versus 'RACE'

P value = 0.0777 (Fisher's exact test), Q value = 0.2

Table S155.  Gene #60: '10p loss' versus Clinical Feature #6: 'RACE'

nPatients AMERICAN INDIAN OR ALASKA NATIVE ASIAN BLACK OR AFRICAN AMERICAN NATIVE HAWAIIAN OR OTHER PACIFIC ISLANDER WHITE
ALL 4 20 101 9 366
10P LOSS MUTATED 0 0 13 2 25
10P LOSS WILD-TYPE 4 20 88 7 341

Figure S155.  Get High-res Image Gene #60: '10p loss' versus Clinical Feature #6: 'RACE'

'10q loss' versus 'Time to Death'

P value = 0.0639 (logrank test), Q value = 0.18

Table S156.  Gene #61: '10q loss' versus Clinical Feature #1: 'Time to Death'

nPatients nDeath Duration Range (Median), Month
ALL 526 69 0.1 - 191.8 (23.3)
10Q LOSS MUTATED 39 9 0.3 - 125.4 (20.5)
10Q LOSS WILD-TYPE 487 60 0.1 - 191.8 (23.3)

Figure S156.  Get High-res Image Gene #61: '10q loss' versus Clinical Feature #1: 'Time to Death'

'10q loss' versus 'YEARS_TO_BIRTH'

P value = 0.0124 (Wilcoxon-test), Q value = 0.049

Table S157.  Gene #61: '10q loss' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

nPatients Mean (Std.Dev)
ALL 526 64.0 (11.2)
10Q LOSS MUTATED 39 68.2 (8.5)
10Q LOSS WILD-TYPE 487 63.7 (11.3)

Figure S157.  Get High-res Image Gene #61: '10q loss' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

'10q loss' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 9.9e-05

Table S158.  Gene #61: '10q loss' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 395 21 112
10Q LOSS MUTATED 12 4 23
10Q LOSS WILD-TYPE 383 17 89

Figure S158.  Get High-res Image Gene #61: '10q loss' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

'11p loss' versus 'Time to Death'

P value = 0.00332 (logrank test), Q value = 0.017

Table S159.  Gene #62: '11p loss' versus Clinical Feature #1: 'Time to Death'

nPatients nDeath Duration Range (Median), Month
ALL 526 69 0.1 - 191.8 (23.3)
11P LOSS MUTATED 73 16 0.3 - 116.2 (19.4)
11P LOSS WILD-TYPE 453 53 0.1 - 191.8 (23.9)

Figure S159.  Get High-res Image Gene #62: '11p loss' versus Clinical Feature #1: 'Time to Death'

'11p loss' versus 'YEARS_TO_BIRTH'

P value = 0.00123 (Wilcoxon-test), Q value = 0.0073

Table S160.  Gene #62: '11p loss' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

nPatients Mean (Std.Dev)
ALL 526 64.0 (11.2)
11P LOSS MUTATED 73 67.9 (9.6)
11P LOSS WILD-TYPE 453 63.4 (11.3)

Figure S160.  Get High-res Image Gene #62: '11p loss' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

'11p loss' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 9.9e-05

Table S161.  Gene #62: '11p loss' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 395 21 112
11P LOSS MUTATED 26 6 41
11P LOSS WILD-TYPE 369 15 71

Figure S161.  Get High-res Image Gene #62: '11p loss' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

'11p loss' versus 'RADIATIONS_RADIATION_REGIMENINDICATION'

P value = 0.0152 (Fisher's exact test), Q value = 0.058

Table S162.  Gene #62: '11p loss' versus Clinical Feature #4: 'RADIATIONS_RADIATION_REGIMENINDICATION'

nPatients NO YES
ALL 141 387
11P LOSS MUTATED 11 62
11P LOSS WILD-TYPE 130 325

Figure S162.  Get High-res Image Gene #62: '11p loss' versus Clinical Feature #4: 'RADIATIONS_RADIATION_REGIMENINDICATION'

'11q loss' versus 'Time to Death'

P value = 0.00962 (logrank test), Q value = 0.04

Table S163.  Gene #63: '11q loss' versus Clinical Feature #1: 'Time to Death'

nPatients nDeath Duration Range (Median), Month
ALL 526 69 0.1 - 191.8 (23.3)
11Q LOSS MUTATED 72 15 0.3 - 116.2 (19.1)
11Q LOSS WILD-TYPE 454 54 0.1 - 191.8 (23.8)

Figure S163.  Get High-res Image Gene #63: '11q loss' versus Clinical Feature #1: 'Time to Death'

'11q loss' versus 'YEARS_TO_BIRTH'

P value = 0.00307 (Wilcoxon-test), Q value = 0.016

Table S164.  Gene #63: '11q loss' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

nPatients Mean (Std.Dev)
ALL 526 64.0 (11.2)
11Q LOSS MUTATED 72 67.7 (9.8)
11Q LOSS WILD-TYPE 454 63.4 (11.3)

Figure S164.  Get High-res Image Gene #63: '11q loss' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

'11q loss' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 9.9e-05

Table S165.  Gene #63: '11q loss' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 395 21 112
11Q LOSS MUTATED 23 7 42
11Q LOSS WILD-TYPE 372 14 70

Figure S165.  Get High-res Image Gene #63: '11q loss' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

'11q loss' versus 'RADIATIONS_RADIATION_REGIMENINDICATION'

P value = 0.000876 (Fisher's exact test), Q value = 0.0056

Table S166.  Gene #63: '11q loss' versus Clinical Feature #4: 'RADIATIONS_RADIATION_REGIMENINDICATION'

nPatients NO YES
ALL 141 387
11Q LOSS MUTATED 8 64
11Q LOSS WILD-TYPE 133 323

Figure S166.  Get High-res Image Gene #63: '11q loss' versus Clinical Feature #4: 'RADIATIONS_RADIATION_REGIMENINDICATION'

'11q loss' versus 'RACE'

P value = 0.0767 (Fisher's exact test), Q value = 0.2

Table S167.  Gene #63: '11q loss' versus Clinical Feature #6: 'RACE'

nPatients AMERICAN INDIAN OR ALASKA NATIVE ASIAN BLACK OR AFRICAN AMERICAN NATIVE HAWAIIAN OR OTHER PACIFIC ISLANDER WHITE
ALL 4 20 101 9 366
11Q LOSS MUTATED 1 1 21 0 44
11Q LOSS WILD-TYPE 3 19 80 9 322

Figure S167.  Get High-res Image Gene #63: '11q loss' versus Clinical Feature #6: 'RACE'

'12p loss' versus 'Time to Death'

P value = 0.00266 (logrank test), Q value = 0.014

Table S168.  Gene #64: '12p loss' versus Clinical Feature #1: 'Time to Death'

nPatients nDeath Duration Range (Median), Month
ALL 526 69 0.1 - 191.8 (23.3)
12P LOSS MUTATED 42 12 4.1 - 102.3 (24.3)
12P LOSS WILD-TYPE 484 57 0.1 - 191.8 (23.3)

Figure S168.  Get High-res Image Gene #64: '12p loss' versus Clinical Feature #1: 'Time to Death'

'12p loss' versus 'YEARS_TO_BIRTH'

P value = 0.0505 (Wilcoxon-test), Q value = 0.15

Table S169.  Gene #64: '12p loss' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

nPatients Mean (Std.Dev)
ALL 526 64.0 (11.2)
12P LOSS MUTATED 42 66.5 (7.9)
12P LOSS WILD-TYPE 484 63.8 (11.4)

Figure S169.  Get High-res Image Gene #64: '12p loss' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

'12p loss' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 9.9e-05

Table S170.  Gene #64: '12p loss' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 395 21 112
12P LOSS MUTATED 13 1 28
12P LOSS WILD-TYPE 382 20 84

Figure S170.  Get High-res Image Gene #64: '12p loss' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

'12p loss' versus 'COMPLETENESS_OF_RESECTION'

P value = 0.0824 (Fisher's exact test), Q value = 0.21

Table S171.  Gene #64: '12p loss' versus Clinical Feature #5: 'COMPLETENESS_OF_RESECTION'

nPatients R0 R1 R2 RX
ALL 363 23 17 35
12P LOSS MUTATED 27 3 4 3
12P LOSS WILD-TYPE 336 20 13 32

Figure S171.  Get High-res Image Gene #64: '12p loss' versus Clinical Feature #5: 'COMPLETENESS_OF_RESECTION'

'12q loss' versus 'Time to Death'

P value = 0.00069 (logrank test), Q value = 0.0045

Table S172.  Gene #65: '12q loss' versus Clinical Feature #1: 'Time to Death'

nPatients nDeath Duration Range (Median), Month
ALL 526 69 0.1 - 191.8 (23.3)
12Q LOSS MUTATED 35 10 4.1 - 97.7 (21.2)
12Q LOSS WILD-TYPE 491 59 0.1 - 191.8 (23.5)

Figure S172.  Get High-res Image Gene #65: '12q loss' versus Clinical Feature #1: 'Time to Death'

'12q loss' versus 'YEARS_TO_BIRTH'

P value = 0.0589 (Wilcoxon-test), Q value = 0.17

Table S173.  Gene #65: '12q loss' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

nPatients Mean (Std.Dev)
ALL 526 64.0 (11.2)
12Q LOSS MUTATED 35 67.0 (9.5)
12Q LOSS WILD-TYPE 491 63.8 (11.3)

Figure S173.  Get High-res Image Gene #65: '12q loss' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

'12q loss' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 9.9e-05

Table S174.  Gene #65: '12q loss' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 395 21 112
12Q LOSS MUTATED 8 1 26
12Q LOSS WILD-TYPE 387 20 86

Figure S174.  Get High-res Image Gene #65: '12q loss' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

'13q loss' versus 'Time to Death'

P value = 0.00368 (logrank test), Q value = 0.019

Table S175.  Gene #66: '13q loss' versus Clinical Feature #1: 'Time to Death'

nPatients nDeath Duration Range (Median), Month
ALL 526 69 0.1 - 191.8 (23.3)
13Q LOSS MUTATED 88 19 0.3 - 149.6 (19.5)
13Q LOSS WILD-TYPE 438 50 0.1 - 191.8 (23.9)

Figure S175.  Get High-res Image Gene #66: '13q loss' versus Clinical Feature #1: 'Time to Death'

'13q loss' versus 'YEARS_TO_BIRTH'

P value = 0.0199 (Wilcoxon-test), Q value = 0.072

Table S176.  Gene #66: '13q loss' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

nPatients Mean (Std.Dev)
ALL 526 64.0 (11.2)
13Q LOSS MUTATED 88 66.5 (9.9)
13Q LOSS WILD-TYPE 438 63.5 (11.4)

Figure S176.  Get High-res Image Gene #66: '13q loss' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

'13q loss' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 9.9e-05

Table S177.  Gene #66: '13q loss' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 395 21 112
13Q LOSS MUTATED 46 5 38
13Q LOSS WILD-TYPE 349 16 74

Figure S177.  Get High-res Image Gene #66: '13q loss' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

'13q loss' versus 'RADIATIONS_RADIATION_REGIMENINDICATION'

P value = 0.025 (Fisher's exact test), Q value = 0.083

Table S178.  Gene #66: '13q loss' versus Clinical Feature #4: 'RADIATIONS_RADIATION_REGIMENINDICATION'

nPatients NO YES
ALL 141 387
13Q LOSS MUTATED 15 74
13Q LOSS WILD-TYPE 126 313

Figure S178.  Get High-res Image Gene #66: '13q loss' versus Clinical Feature #4: 'RADIATIONS_RADIATION_REGIMENINDICATION'

'14q loss' versus 'Time to Death'

P value = 0.011 (logrank test), Q value = 0.044

Table S179.  Gene #67: '14q loss' versus Clinical Feature #1: 'Time to Death'

nPatients nDeath Duration Range (Median), Month
ALL 526 69 0.1 - 191.8 (23.3)
14Q LOSS MUTATED 59 13 0.3 - 125.4 (20.0)
14Q LOSS WILD-TYPE 467 56 0.1 - 191.8 (23.6)

Figure S179.  Get High-res Image Gene #67: '14q loss' versus Clinical Feature #1: 'Time to Death'

'14q loss' versus 'YEARS_TO_BIRTH'

P value = 0.00425 (Wilcoxon-test), Q value = 0.021

Table S180.  Gene #67: '14q loss' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

nPatients Mean (Std.Dev)
ALL 526 64.0 (11.2)
14Q LOSS MUTATED 59 67.8 (8.7)
14Q LOSS WILD-TYPE 467 63.5 (11.4)

Figure S180.  Get High-res Image Gene #67: '14q loss' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

'14q loss' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 9.9e-05

Table S181.  Gene #67: '14q loss' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 395 21 112
14Q LOSS MUTATED 19 3 37
14Q LOSS WILD-TYPE 376 18 75

Figure S181.  Get High-res Image Gene #67: '14q loss' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

'14q loss' versus 'RACE'

P value = 0.00729 (Fisher's exact test), Q value = 0.032

Table S182.  Gene #67: '14q loss' versus Clinical Feature #6: 'RACE'

nPatients AMERICAN INDIAN OR ALASKA NATIVE ASIAN BLACK OR AFRICAN AMERICAN NATIVE HAWAIIAN OR OTHER PACIFIC ISLANDER WHITE
ALL 4 20 101 9 366
14Q LOSS MUTATED 1 2 21 1 30
14Q LOSS WILD-TYPE 3 18 80 8 336

Figure S182.  Get High-res Image Gene #67: '14q loss' versus Clinical Feature #6: 'RACE'

'15q loss' versus 'Time to Death'

P value = 0.00117 (logrank test), Q value = 0.007

Table S183.  Gene #68: '15q loss' versus Clinical Feature #1: 'Time to Death'

nPatients nDeath Duration Range (Median), Month
ALL 526 69 0.1 - 191.8 (23.3)
15Q LOSS MUTATED 105 23 0.2 - 125.4 (20.0)
15Q LOSS WILD-TYPE 421 46 0.1 - 191.8 (24.1)

Figure S183.  Get High-res Image Gene #68: '15q loss' versus Clinical Feature #1: 'Time to Death'

'15q loss' versus 'YEARS_TO_BIRTH'

P value = 2.54e-06 (Wilcoxon-test), Q value = 9.9e-05

Table S184.  Gene #68: '15q loss' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

nPatients Mean (Std.Dev)
ALL 526 64.0 (11.2)
15Q LOSS MUTATED 105 68.5 (10.2)
15Q LOSS WILD-TYPE 421 62.9 (11.2)

Figure S184.  Get High-res Image Gene #68: '15q loss' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

'15q loss' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 9.9e-05

Table S185.  Gene #68: '15q loss' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 395 21 112
15Q LOSS MUTATED 36 8 61
15Q LOSS WILD-TYPE 359 13 51

Figure S185.  Get High-res Image Gene #68: '15q loss' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

'15q loss' versus 'RADIATIONS_RADIATION_REGIMENINDICATION'

P value = 0.0493 (Fisher's exact test), Q value = 0.14

Table S186.  Gene #68: '15q loss' versus Clinical Feature #4: 'RADIATIONS_RADIATION_REGIMENINDICATION'

nPatients NO YES
ALL 141 387
15Q LOSS MUTATED 20 85
15Q LOSS WILD-TYPE 121 302

Figure S186.  Get High-res Image Gene #68: '15q loss' versus Clinical Feature #4: 'RADIATIONS_RADIATION_REGIMENINDICATION'

'16p loss' versus 'Time to Death'

P value = 0.00321 (logrank test), Q value = 0.017

Table S187.  Gene #69: '16p loss' versus Clinical Feature #1: 'Time to Death'

nPatients nDeath Duration Range (Median), Month
ALL 526 69 0.1 - 191.8 (23.3)
16P LOSS MUTATED 95 20 0.2 - 110.1 (22.3)
16P LOSS WILD-TYPE 431 49 0.1 - 191.8 (23.5)

Figure S187.  Get High-res Image Gene #69: '16p loss' versus Clinical Feature #1: 'Time to Death'

'16p loss' versus 'YEARS_TO_BIRTH'

P value = 4.74e-05 (Wilcoxon-test), Q value = 0.00041

Table S188.  Gene #69: '16p loss' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

nPatients Mean (Std.Dev)
ALL 526 64.0 (11.2)
16P LOSS MUTATED 96 67.9 (9.6)
16P LOSS WILD-TYPE 430 63.1 (11.4)

Figure S188.  Get High-res Image Gene #69: '16p loss' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

'16p loss' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 9.9e-05

Table S189.  Gene #69: '16p loss' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 395 21 112
16P LOSS MUTATED 32 6 58
16P LOSS WILD-TYPE 363 15 54

Figure S189.  Get High-res Image Gene #69: '16p loss' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

'16p loss' versus 'RADIATIONS_RADIATION_REGIMENINDICATION'

P value = 0.0982 (Fisher's exact test), Q value = 0.25

Table S190.  Gene #69: '16p loss' versus Clinical Feature #4: 'RADIATIONS_RADIATION_REGIMENINDICATION'

nPatients NO YES
ALL 141 387
16P LOSS MUTATED 19 77
16P LOSS WILD-TYPE 122 310

Figure S190.  Get High-res Image Gene #69: '16p loss' versus Clinical Feature #4: 'RADIATIONS_RADIATION_REGIMENINDICATION'

'16p loss' versus 'COMPLETENESS_OF_RESECTION'

P value = 0.0207 (Fisher's exact test), Q value = 0.073

Table S191.  Gene #69: '16p loss' versus Clinical Feature #5: 'COMPLETENESS_OF_RESECTION'

nPatients R0 R1 R2 RX
ALL 363 23 17 35
16P LOSS MUTATED 55 5 7 9
16P LOSS WILD-TYPE 308 18 10 26

Figure S191.  Get High-res Image Gene #69: '16p loss' versus Clinical Feature #5: 'COMPLETENESS_OF_RESECTION'

'16q loss' versus 'Time to Death'

P value = 0.0184 (logrank test), Q value = 0.068

Table S192.  Gene #70: '16q loss' versus Clinical Feature #1: 'Time to Death'

nPatients nDeath Duration Range (Median), Month
ALL 526 69 0.1 - 191.8 (23.3)
16Q LOSS MUTATED 135 25 0.1 - 113.4 (22.3)
16Q LOSS WILD-TYPE 391 44 0.1 - 191.8 (23.5)

Figure S192.  Get High-res Image Gene #70: '16q loss' versus Clinical Feature #1: 'Time to Death'

'16q loss' versus 'YEARS_TO_BIRTH'

P value = 3.9e-07 (Wilcoxon-test), Q value = 7.5e-05

Table S193.  Gene #70: '16q loss' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

nPatients Mean (Std.Dev)
ALL 526 64.0 (11.2)
16Q LOSS MUTATED 136 67.9 (9.3)
16Q LOSS WILD-TYPE 390 62.6 (11.5)

Figure S193.  Get High-res Image Gene #70: '16q loss' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

'16q loss' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 9.9e-05

Table S194.  Gene #70: '16q loss' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 395 21 112
16Q LOSS MUTATED 55 7 74
16Q LOSS WILD-TYPE 340 14 38

Figure S194.  Get High-res Image Gene #70: '16q loss' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

'16q loss' versus 'RADIATIONS_RADIATION_REGIMENINDICATION'

P value = 0.0426 (Fisher's exact test), Q value = 0.13

Table S195.  Gene #70: '16q loss' versus Clinical Feature #4: 'RADIATIONS_RADIATION_REGIMENINDICATION'

nPatients NO YES
ALL 141 387
16Q LOSS MUTATED 27 109
16Q LOSS WILD-TYPE 114 278

Figure S195.  Get High-res Image Gene #70: '16q loss' versus Clinical Feature #4: 'RADIATIONS_RADIATION_REGIMENINDICATION'

'16q loss' versus 'COMPLETENESS_OF_RESECTION'

P value = 0.0251 (Fisher's exact test), Q value = 0.083

Table S196.  Gene #70: '16q loss' versus Clinical Feature #5: 'COMPLETENESS_OF_RESECTION'

nPatients R0 R1 R2 RX
ALL 363 23 17 35
16Q LOSS MUTATED 79 8 8 12
16Q LOSS WILD-TYPE 284 15 9 23

Figure S196.  Get High-res Image Gene #70: '16q loss' versus Clinical Feature #5: 'COMPLETENESS_OF_RESECTION'

'16q loss' versus 'RACE'

P value = 0.0327 (Fisher's exact test), Q value = 0.1

Table S197.  Gene #70: '16q loss' versus Clinical Feature #6: 'RACE'

nPatients AMERICAN INDIAN OR ALASKA NATIVE ASIAN BLACK OR AFRICAN AMERICAN NATIVE HAWAIIAN OR OTHER PACIFIC ISLANDER WHITE
ALL 4 20 101 9 366
16Q LOSS MUTATED 1 2 37 2 85
16Q LOSS WILD-TYPE 3 18 64 7 281

Figure S197.  Get High-res Image Gene #70: '16q loss' versus Clinical Feature #6: 'RACE'

'17p loss' versus 'Time to Death'

P value = 0.000538 (logrank test), Q value = 0.0037

Table S198.  Gene #71: '17p loss' versus Clinical Feature #1: 'Time to Death'

nPatients nDeath Duration Range (Median), Month
ALL 526 69 0.1 - 191.8 (23.3)
17P LOSS MUTATED 124 27 0.2 - 125.4 (20.2)
17P LOSS WILD-TYPE 402 42 0.1 - 191.8 (23.9)

Figure S198.  Get High-res Image Gene #71: '17p loss' versus Clinical Feature #1: 'Time to Death'

'17p loss' versus 'YEARS_TO_BIRTH'

P value = 7.32e-06 (Wilcoxon-test), Q value = 9.9e-05

Table S199.  Gene #71: '17p loss' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

nPatients Mean (Std.Dev)
ALL 526 64.0 (11.2)
17P LOSS MUTATED 124 67.7 (9.0)
17P LOSS WILD-TYPE 402 62.9 (11.6)

Figure S199.  Get High-res Image Gene #71: '17p loss' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

'17p loss' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 9.9e-05

Table S200.  Gene #71: '17p loss' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 395 21 112
17P LOSS MUTATED 44 9 72
17P LOSS WILD-TYPE 351 12 40

Figure S200.  Get High-res Image Gene #71: '17p loss' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

'17p loss' versus 'RACE'

P value = 0.00859 (Fisher's exact test), Q value = 0.036

Table S201.  Gene #71: '17p loss' versus Clinical Feature #6: 'RACE'

nPatients AMERICAN INDIAN OR ALASKA NATIVE ASIAN BLACK OR AFRICAN AMERICAN NATIVE HAWAIIAN OR OTHER PACIFIC ISLANDER WHITE
ALL 4 20 101 9 366
17P LOSS MUTATED 1 1 35 3 77
17P LOSS WILD-TYPE 3 19 66 6 289

Figure S201.  Get High-res Image Gene #71: '17p loss' versus Clinical Feature #6: 'RACE'

'17q loss' versus 'Time to Death'

P value = 0.00489 (logrank test), Q value = 0.024

Table S202.  Gene #72: '17q loss' versus Clinical Feature #1: 'Time to Death'

nPatients nDeath Duration Range (Median), Month
ALL 526 69 0.1 - 191.8 (23.3)
17Q LOSS MUTATED 88 20 0.2 - 125.4 (21.7)
17Q LOSS WILD-TYPE 438 49 0.1 - 191.8 (23.5)

Figure S202.  Get High-res Image Gene #72: '17q loss' versus Clinical Feature #1: 'Time to Death'

'17q loss' versus 'YEARS_TO_BIRTH'

P value = 0.000168 (Wilcoxon-test), Q value = 0.0012

Table S203.  Gene #72: '17q loss' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

nPatients Mean (Std.Dev)
ALL 526 64.0 (11.2)
17Q LOSS MUTATED 89 67.8 (9.7)
17Q LOSS WILD-TYPE 437 63.2 (11.4)

Figure S203.  Get High-res Image Gene #72: '17q loss' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

'17q loss' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 9.9e-05

Table S204.  Gene #72: '17q loss' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 395 21 112
17Q LOSS MUTATED 35 7 47
17Q LOSS WILD-TYPE 360 14 65

Figure S204.  Get High-res Image Gene #72: '17q loss' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

'17q loss' versus 'ETHNICITY'

P value = 0.0713 (Fisher's exact test), Q value = 0.19

Table S205.  Gene #72: '17q loss' versus Clinical Feature #7: 'ETHNICITY'

nPatients HISPANIC OR LATINO NOT HISPANIC OR LATINO
ALL 14 367
17Q LOSS MUTATED 5 60
17Q LOSS WILD-TYPE 9 307

Figure S205.  Get High-res Image Gene #72: '17q loss' versus Clinical Feature #7: 'ETHNICITY'

'18p loss' versus 'YEARS_TO_BIRTH'

P value = 0.0205 (Wilcoxon-test), Q value = 0.073

Table S206.  Gene #73: '18p loss' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

nPatients Mean (Std.Dev)
ALL 526 64.0 (11.2)
18P LOSS MUTATED 50 66.8 (10.3)
18P LOSS WILD-TYPE 476 63.7 (11.3)

Figure S206.  Get High-res Image Gene #73: '18p loss' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

'18p loss' versus 'HISTOLOGICAL_TYPE'

P value = 5e-05 (Fisher's exact test), Q value = 0.00042

Table S207.  Gene #73: '18p loss' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 395 21 112
18P LOSS MUTATED 24 5 21
18P LOSS WILD-TYPE 371 16 91

Figure S207.  Get High-res Image Gene #73: '18p loss' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

'18q loss' versus 'YEARS_TO_BIRTH'

P value = 0.0199 (Wilcoxon-test), Q value = 0.072

Table S208.  Gene #74: '18q loss' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

nPatients Mean (Std.Dev)
ALL 526 64.0 (11.2)
18Q LOSS MUTATED 63 66.5 (9.7)
18Q LOSS WILD-TYPE 463 63.7 (11.4)

Figure S208.  Get High-res Image Gene #74: '18q loss' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

'18q loss' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 9.9e-05

Table S209.  Gene #74: '18q loss' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 395 21 112
18Q LOSS MUTATED 27 6 30
18Q LOSS WILD-TYPE 368 15 82

Figure S209.  Get High-res Image Gene #74: '18q loss' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

'19p loss' versus 'Time to Death'

P value = 0.00181 (logrank test), Q value = 0.01

Table S210.  Gene #75: '19p loss' versus Clinical Feature #1: 'Time to Death'

nPatients nDeath Duration Range (Median), Month
ALL 526 69 0.1 - 191.8 (23.3)
19P LOSS MUTATED 59 15 0.2 - 116.2 (20.3)
19P LOSS WILD-TYPE 467 54 0.1 - 191.8 (23.5)

Figure S210.  Get High-res Image Gene #75: '19p loss' versus Clinical Feature #1: 'Time to Death'

'19p loss' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 9.9e-05

Table S211.  Gene #75: '19p loss' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 395 21 112
19P LOSS MUTATED 18 4 37
19P LOSS WILD-TYPE 377 17 75

Figure S211.  Get High-res Image Gene #75: '19p loss' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

'19q loss' versus 'Time to Death'

P value = 0.00514 (logrank test), Q value = 0.025

Table S212.  Gene #76: '19q loss' versus Clinical Feature #1: 'Time to Death'

nPatients nDeath Duration Range (Median), Month
ALL 526 69 0.1 - 191.8 (23.3)
19Q LOSS MUTATED 56 15 0.2 - 125.4 (23.8)
19Q LOSS WILD-TYPE 470 54 0.1 - 191.8 (23.3)

Figure S212.  Get High-res Image Gene #76: '19q loss' versus Clinical Feature #1: 'Time to Death'

'19q loss' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 9.9e-05

Table S213.  Gene #76: '19q loss' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 395 21 112
19Q LOSS MUTATED 18 4 34
19Q LOSS WILD-TYPE 377 17 78

Figure S213.  Get High-res Image Gene #76: '19q loss' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

'20p loss' versus 'HISTOLOGICAL_TYPE'

P value = 0.00972 (Fisher's exact test), Q value = 0.04

Table S214.  Gene #77: '20p loss' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 395 21 112
20P LOSS MUTATED 8 1 9
20P LOSS WILD-TYPE 387 20 103

Figure S214.  Get High-res Image Gene #77: '20p loss' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

'20q loss' versus 'HISTOLOGICAL_TYPE'

P value = 0.00687 (Fisher's exact test), Q value = 0.031

Table S215.  Gene #78: '20q loss' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 395 21 112
20Q LOSS MUTATED 3 2 4
20Q LOSS WILD-TYPE 392 19 108

Figure S215.  Get High-res Image Gene #78: '20q loss' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

'20q loss' versus 'RADIATIONS_RADIATION_REGIMENINDICATION'

P value = 0.0618 (Fisher's exact test), Q value = 0.17

Table S216.  Gene #78: '20q loss' versus Clinical Feature #4: 'RADIATIONS_RADIATION_REGIMENINDICATION'

nPatients NO YES
ALL 141 387
20Q LOSS MUTATED 5 4
20Q LOSS WILD-TYPE 136 383

Figure S216.  Get High-res Image Gene #78: '20q loss' versus Clinical Feature #4: 'RADIATIONS_RADIATION_REGIMENINDICATION'

'21q loss' versus 'Time to Death'

P value = 0.059 (logrank test), Q value = 0.17

Table S217.  Gene #79: '21q loss' versus Clinical Feature #1: 'Time to Death'

nPatients nDeath Duration Range (Median), Month
ALL 526 69 0.1 - 191.8 (23.3)
21Q LOSS MUTATED 53 10 0.3 - 125.4 (19.3)
21Q LOSS WILD-TYPE 473 59 0.1 - 191.8 (23.9)

Figure S217.  Get High-res Image Gene #79: '21q loss' versus Clinical Feature #1: 'Time to Death'

'21q loss' versus 'YEARS_TO_BIRTH'

P value = 0.00922 (Wilcoxon-test), Q value = 0.039

Table S218.  Gene #79: '21q loss' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

nPatients Mean (Std.Dev)
ALL 526 64.0 (11.2)
21Q LOSS MUTATED 53 67.6 (9.5)
21Q LOSS WILD-TYPE 473 63.6 (11.3)

Figure S218.  Get High-res Image Gene #79: '21q loss' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

'21q loss' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 9.9e-05

Table S219.  Gene #79: '21q loss' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 395 21 112
21Q LOSS MUTATED 19 4 30
21Q LOSS WILD-TYPE 376 17 82

Figure S219.  Get High-res Image Gene #79: '21q loss' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

'22q loss' versus 'Time to Death'

P value = 0.00604 (logrank test), Q value = 0.028

Table S220.  Gene #80: '22q loss' versus Clinical Feature #1: 'Time to Death'

nPatients nDeath Duration Range (Median), Month
ALL 526 69 0.1 - 191.8 (23.3)
22Q LOSS MUTATED 105 21 0.1 - 116.2 (20.0)
22Q LOSS WILD-TYPE 421 48 0.1 - 191.8 (23.7)

Figure S220.  Get High-res Image Gene #80: '22q loss' versus Clinical Feature #1: 'Time to Death'

'22q loss' versus 'YEARS_TO_BIRTH'

P value = 6.81e-05 (Wilcoxon-test), Q value = 0.00056

Table S221.  Gene #80: '22q loss' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

nPatients Mean (Std.Dev)
ALL 526 64.0 (11.2)
22Q LOSS MUTATED 105 67.7 (8.8)
22Q LOSS WILD-TYPE 421 63.1 (11.6)

Figure S221.  Get High-res Image Gene #80: '22q loss' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

'22q loss' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 9.9e-05

Table S222.  Gene #80: '22q loss' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 395 21 112
22Q LOSS MUTATED 44 10 52
22Q LOSS WILD-TYPE 351 11 60

Figure S222.  Get High-res Image Gene #80: '22q loss' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

'22q loss' versus 'RADIATIONS_RADIATION_REGIMENINDICATION'

P value = 0.049 (Fisher's exact test), Q value = 0.14

Table S223.  Gene #80: '22q loss' versus Clinical Feature #4: 'RADIATIONS_RADIATION_REGIMENINDICATION'

nPatients NO YES
ALL 141 387
22Q LOSS MUTATED 20 86
22Q LOSS WILD-TYPE 121 301

Figure S223.  Get High-res Image Gene #80: '22q loss' versus Clinical Feature #4: 'RADIATIONS_RADIATION_REGIMENINDICATION'

'xp loss' versus 'Time to Death'

P value = 8.84e-05 (logrank test), Q value = 0.00069

Table S224.  Gene #81: 'xp loss' versus Clinical Feature #1: 'Time to Death'

nPatients nDeath Duration Range (Median), Month
ALL 526 69 0.1 - 191.8 (23.3)
XP LOSS MUTATED 79 21 0.3 - 110.1 (22.0)
XP LOSS WILD-TYPE 447 48 0.1 - 191.8 (23.6)

Figure S224.  Get High-res Image Gene #81: 'xp loss' versus Clinical Feature #1: 'Time to Death'

'xp loss' versus 'YEARS_TO_BIRTH'

P value = 0.000212 (Wilcoxon-test), Q value = 0.0015

Table S225.  Gene #81: 'xp loss' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

nPatients Mean (Std.Dev)
ALL 526 64.0 (11.2)
XP LOSS MUTATED 79 68.0 (9.5)
XP LOSS WILD-TYPE 447 63.3 (11.4)

Figure S225.  Get High-res Image Gene #81: 'xp loss' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

'xp loss' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 9.9e-05

Table S226.  Gene #81: 'xp loss' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 395 21 112
XP LOSS MUTATED 31 4 45
XP LOSS WILD-TYPE 364 17 67

Figure S226.  Get High-res Image Gene #81: 'xp loss' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

'xp loss' versus 'RADIATIONS_RADIATION_REGIMENINDICATION'

P value = 0.0992 (Fisher's exact test), Q value = 0.25

Table S227.  Gene #81: 'xp loss' versus Clinical Feature #4: 'RADIATIONS_RADIATION_REGIMENINDICATION'

nPatients NO YES
ALL 141 387
XP LOSS MUTATED 15 65
XP LOSS WILD-TYPE 126 322

Figure S227.  Get High-res Image Gene #81: 'xp loss' versus Clinical Feature #4: 'RADIATIONS_RADIATION_REGIMENINDICATION'

'xq loss' versus 'Time to Death'

P value = 0.00848 (logrank test), Q value = 0.036

Table S228.  Gene #82: 'xq loss' versus Clinical Feature #1: 'Time to Death'

nPatients nDeath Duration Range (Median), Month
ALL 526 69 0.1 - 191.8 (23.3)
XQ LOSS MUTATED 68 15 0.3 - 110.1 (19.7)
XQ LOSS WILD-TYPE 458 54 0.1 - 191.8 (23.6)

Figure S228.  Get High-res Image Gene #82: 'xq loss' versus Clinical Feature #1: 'Time to Death'

'xq loss' versus 'YEARS_TO_BIRTH'

P value = 0.000693 (Wilcoxon-test), Q value = 0.0045

Table S229.  Gene #82: 'xq loss' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

nPatients Mean (Std.Dev)
ALL 526 64.0 (11.2)
XQ LOSS MUTATED 68 68.1 (9.5)
XQ LOSS WILD-TYPE 458 63.4 (11.3)

Figure S229.  Get High-res Image Gene #82: 'xq loss' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

'xq loss' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 9.9e-05

Table S230.  Gene #82: 'xq loss' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 395 21 112
XQ LOSS MUTATED 30 3 36
XQ LOSS WILD-TYPE 365 18 76

Figure S230.  Get High-res Image Gene #82: 'xq loss' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

'xq loss' versus 'RADIATIONS_RADIATION_REGIMENINDICATION'

P value = 0.0789 (Fisher's exact test), Q value = 0.21

Table S231.  Gene #82: 'xq loss' versus Clinical Feature #4: 'RADIATIONS_RADIATION_REGIMENINDICATION'

nPatients NO YES
ALL 141 387
XQ LOSS MUTATED 12 57
XQ LOSS WILD-TYPE 129 330

Figure S231.  Get High-res Image Gene #82: 'xq loss' versus Clinical Feature #4: 'RADIATIONS_RADIATION_REGIMENINDICATION'

Methods & Data
Input

  • Copy number data file = broad_values_by_arm.txt from GISTIC pipeline

  • Processed Copy number data file = /xchip/cga/gdac-prod/tcga-gdac/jobResults/GDAC_Correlate_Genomic_Events_Preprocess/UCEC-TP/15106276/transformed.cor.cli.txt

  • Clinical data file = /xchip/cga/gdac-prod/tcga-gdac/jobResults/Append_Data/UCEC-TP/15094079/UCEC-TP.merged_data.txt

  • Number of patients = 528

  • Number of significantly arm-level cnvs = 82

  • Number of selected clinical features = 7

  • Exclude regions that fewer than K tumors have mutations, K = 3

Survival analysis

For survival clinical features, the Kaplan-Meier survival curves of tumors with and without gene mutations were plotted and the statistical significance P values were estimated by logrank test (Bland and Altman 2004) using the 'survdiff' function in R

Fisher's exact test

For binary or multi-class clinical features (nominal or ordinal), two-tailed Fisher's exact tests (Fisher 1922) were used to estimate the P values using the 'fisher.test' function in R

Q value calculation

For multiple hypothesis correction, Q value is the False Discovery Rate (FDR) analogue of the P value (Benjamini and Hochberg 1995), defined as the minimum FDR at which the test may be called significant. We used the 'Benjamini and Hochberg' method of 'p.adjust' function in R to convert P values into Q values.

Download Results

In addition to the links below, the full results of the analysis summarized in this report can also be downloaded programmatically using firehose_get, or interactively from either the Broad GDAC website or TCGA Data Coordination Center Portal.

References
[1] Bland and Altman, Statistics notes: The logrank test, BMJ 328(7447):1073 (2004)
[2] Fisher, R.A., On the interpretation of chi-square from contingency tables, and the calculation of P, Journal of the Royal Statistical Society 85(1):87-94 (1922)
[3] Benjamini and Hochberg, Controlling the false discovery rate: a practical and powerful approach to multiple testing, Journal of the Royal Statistical Society Series B 59:289-300 (1995)
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