Signaling events mediated by the Hedgehog family
Entity	Mean	Std Dev	Mean of Up Perturbations	Number of Up Perturbations	Mean of Down Perturbations	Number of Down Perturbations	Number of Total Perturbations
TGFB2	-0.042	0.154	0.244	7.0	-0.537	31.0	38.0
IHH	-0.041	0.21	0.31	58.0	-0.382	125.0	183.0
SHH Np/Cholesterol/GAS1	-0.083	0.103	0.23	1.0	-0.186	261.0	262.0
LRPAP1	0.022	0.004	-9999.0	0.0	-9999.0	0.0	0.0
dorsoventral neural tube patterning	0.083	0.102	0.185	261.0	-0.228	1.0	262.0
SMO/beta Arrestin2	-0.038	0.157	-9999.0	0.0	-0.311	107.0	107.0
SMO	-0.056	0.153	-9999.0	0.0	-0.324	110.0	110.0
AKT1	-0.018	0.124	-9999.0	0.0	-0.49	20.0	20.0
ARRB2	0.021	0.006	-9999.0	0.0	-9999.0	0.0	0.0
BOC	0.011	0.065	-9999.0	0.0	-0.35	17.0	17.0
ADRBK1	0.023	0.004	-9999.0	0.0	-9999.0	0.0	0.0
heart looping	-0.054	0.152	-9999.0	0.0	-0.321	110.0	110.0
STIL	-0.011	0.118	0.185	62.0	-0.274	29.0	91.0
DHH N/PTCH2	-0.004	0.099	-9999.0	0.0	-0.257	69.0	69.0
DHH N/PTCH1	-0.042	0.131	-9999.0	0.0	-0.232	151.0	151.0
PIK3CA	0.02	0.018	-9999.0	0.0	-0.35	1.0	1.0
DHH	-0.008	0.102	-9999.0	0.0	-0.35	44.0	44.0
PTHLH	-0.061	0.189	-9999.0	0.0	-0.586	32.0	32.0
determination of left/right symmetry	-0.054	0.152	-9999.0	0.0	-0.321	110.0	110.0
PIK3R1	0.018	0.036	-9999.0	0.0	-0.35	5.0	5.0
skeletal system development	-0.06	0.187	-9999.0	0.0	-0.58	32.0	32.0
IHH N/Hhip	-0.004	0.142	0.219	73.0	-0.229	122.0	195.0
DHH N/Hhip	0.016	0.091	0.208	26.0	-0.244	49.0	75.0
mol:Cholesterol	0.0	0.0	-9999.0	0.0	-9999.0	0.0	0.0
heart development	-0.054	0.152	-9999.0	0.0	-0.321	110.0	110.0
pancreas development	0.032	0.068	0.279	28.0	-0.35	5.0	33.0
HHAT	0.017	0.033	-9999.0	0.0	-0.35	4.0	4.0
PI3K	0.027	0.029	-9999.0	0.0	-0.246	5.0	5.0
EntrezGene:84976	0.0	0.0	-9999.0	0.0	-9999.0	0.0	0.0
GAS1	-0.201	0.181	-9999.0	0.0	-0.35	321.0	321.0
somite specification	-0.054	0.152	-9999.0	0.0	-0.321	110.0	110.0
SHH Np/Cholesterol/PTCH1	-0.022	0.109	0.241	5.0	-0.205	109.0	114.0
SHH Np/Cholesterol/PTCH2	0.015	0.059	0.224	6.0	-0.197	28.0	34.0
SHH Np/Cholesterol/Megalin	0.079	0.094	0.204	173.0	-0.176	6.0	179.0
SHH	0.004	0.058	0.13	64.0	-0.246	6.0	70.0
catabolic process	-0.036	0.125	-9999.0	0.0	-0.25	128.0	128.0
SMO/Vitamin D3	-0.014	0.148	0.273	12.0	-0.258	117.0	129.0
SHH Np/Cholesterol/Hhip	0.03	0.059	0.206	33.0	-0.185	11.0	44.0
LRP2	0.11	0.122	0.28	184.0	-9999.0	0.0	184.0
receptor-mediated endocytosis	-0.008	0.139	0.218	22.0	-0.312	35.0	57.0
SHH Np/Cholesterol/BOC	0.017	0.054	0.224	6.0	-0.193	22.0	28.0
SHH Np/Cholesterol/CDO	0.006	0.069	0.224	6.0	-0.19	47.0	53.0
mesenchymal cell differentiation	-0.03	0.059	0.184	11.0	-0.203	33.0	44.0
mol:Vitamin D3	0.0	0.134	0.293	16.0	-0.207	108.0	124.0
IHH N/PTCH2	-0.021	0.146	0.199	57.0	-0.25	134.0	191.0
CDON	-0.014	0.11	-9999.0	0.0	-0.35	52.0	52.0
IHH N/PTCH1	-0.025	0.146	-9999.0	0.0	-0.247	139.0	139.0
Megalin/LRPAP1	0.09	0.084	0.209	177.0	-9999.0	0.0	177.0
PTCH2	0.002	0.084	-9999.0	0.0	-0.35	29.0	29.0
SHH Np/Cholesterol	0.008	0.022	-9999.0	0.0	-0.184	6.0	6.0
PTCH1	-0.037	0.126	-9999.0	0.0	-0.25	128.0	128.0
HHIP	0.032	0.068	0.279	28.0	-0.35	5.0	33.0