Clinical Features CN_CNMF METHLYATION_CNMF RPPA_CNMF RPPA_CHIERARCHICAL MRNASEQ_CNMF MRNASEQ_CHIERARCHICAL MIRSEQ_CNMF MIRSEQ_CHIERARCHICAL MIRSEQ_MATURE_CNMF MIRSEQ_MATURE_CHIERARCHICAL nMutated (%) nWild-Type Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q TP53 51 (89%) 6 0.56639 0.953 0.62857 0.98 0.64127 0.98 0.13826 0.618 0.87812 1 0.51041 0.909 1 1 0.91193 1 1 1 1 1 FBXW7 22 (39%) 35 0.26392 0.762 0.7239 0.98 0.1437 0.618 0.16788 0.624 0.63179 0.98 0.10331 0.539 0.46919 0.89 0.93063 1 1 1 0.77347 0.999 PPP2R1A 16 (28%) 41 0.76168 0.999 0.70942 0.98 0.19226 0.627 0.50131 0.909 0.59043 0.972 0.67346 0.98 0.56806 0.953 0.319 0.79 0.69662 0.98 0.23448 0.693 PTEN 11 (19%) 46 0.093499 0.539 5.9999e-05 0.0078 1 1 0.01815 0.262 0.00216 0.14 0.04674 0.506 0.095209 0.539 0.059789 0.539 0.00343 0.149 0.01362 0.241 KRAS 7 (12%) 50 0.10363 0.539 0.01483 0.241 1 1 0.20348 0.645 0.03302 0.427 0.0067699 0.176 0.46596 0.89 0.090529 0.539 0.30849 0.79 0.058549 0.539 ZBTB7B 6 (11%) 51 0.72001 0.98 0.93877 1 0.64127 0.98 0.37683 0.79 1 1 0.91449 1 0.096329 0.539 0.14814 0.618 0.47934 0.89 0.16223 0.62 CHD4 10 (18%) 47 0.34565 0.79 0.01024 0.222 0.7119 0.98 0.16081 0.62 0.18426 0.627 0.0052499 0.171 0.47783 0.89 0.41015 0.82 0.088659 0.539 0.21672 0.671 PIK3R1 6 (11%) 51 1 1 0.93924 1 0.38266 0.79 0.77606 0.999 0.54421 0.953 0.70556 0.98 0.42404 0.835 0.50586 0.909 1 1 0.30711 0.79 ARHGAP35 6 (11%) 51 0.57194 0.953 0.33255 0.79 1 1 0.34258 0.79 1 1 0.40026 0.813 1 1 0.19083 0.627 1 1 0.17617 0.627 PIK3CA 20 (35%) 37 0.63782 0.98 0.90051 1 0.13312 0.618 0.29467 0.79 0.36185 0.79 0.36883 0.79 0.11211 0.561 0.3387 0.79 0.19305 0.627 0.26986 0.763 MAMLD1 4 (7%) 53 1 1 0.9028 1 0.12095 0.582 0.03617 0.427 0.68796 0.98 0.76834 0.999 0.064499 0.539 0.67791 0.98 0.15208 0.618 0.35434 0.79 RB1 6 (11%) 51 0.22682 0.686 0.090649 0.539 0.36864 0.79 0.31267 0.79 0.078749 0.539 0.098129 0.539 0.83683 1 0.86034 1 0.86597 1 1 1 LYPLA2 3 (5%) 54 0.76737 0.999 0.61693 0.98 1 1 0.83824 1 0.67815 0.98 0.34754 0.79 0.37816 0.79 0.5637 0.953 1 1 0.69278 0.98