		Clinical Features	CN_CNMF		METHLYATION_CNMF		RPPA_CNMF		RPPA_CHIERARCHICAL		MRNASEQ_CNMF		MRNASEQ_CHIERARCHICAL		MIRSEQ_CNMF		MIRSEQ_CHIERARCHICAL		MIRSEQ_MATURE_CNMF		MIRSEQ_MATURE_CHIERARCHICAL	
	nMutated (%)	nWild-Type	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q
PTEN	15 (8%)	179	0.56821	0.745	0.34232	0.611	0.62019	0.775	0.58992	0.761	0.02631	0.197	0.22826	0.537	0.43211	0.681	0.19301	0.508	1	1	0.42103	0.681
HLA-B	11 (6%)	183	0.51884	0.729	0.16381	0.479	0.42806	0.681	0.32574	0.611	0.23836	0.544	0.092409	0.348	0.01882	0.186	0.1346	0.426	0.01245	0.146	0.04818	0.268
HLA-A	16 (8%)	178	0.25927	0.558	0.093829	0.348	0.34365	0.611	0.01712	0.186	0.00085999	0.046	0.067589	0.314	0.43009	0.681	0.0076999	0.11	0.69247	0.815	0.41779	0.681
KRAS	11 (6%)	183	0.56622	0.745	0.00408	0.0792	0.40012	0.668	0.21924	0.537	0.00451	0.0792	0.00158	0.0632	0.00319	0.0792	0.00091999	0.046	0.0363	0.234	0.00016	0.032
MLL2	22 (11%)	172	0.67201	0.808	0.24188	0.544	0.89423	0.983	0.24049	0.544	0.52106	0.729	0.079689	0.335	0.88199	0.975	0.3126	0.611	0.090409	0.348	0.73593	0.856
FBXW7	19 (10%)	175	0.49627	0.709	0.25833	0.558	0.32895	0.611	0.97186	1	0.3421	0.611	0.67845	0.808	0.40058	0.668	0.45529	0.685	0.22417	0.537	0.53944	0.739
EP300	21 (11%)	173	1	1	0.02656	0.197	0.7644	0.874	0.03866	0.242	0.13618	0.426	0.072889	0.317	0.83884	0.937	0.0095599	0.121	1	1	0.24741	0.55
MAPK1	9 (5%)	185	0.55046	0.739	0.22766	0.537	0.2751	0.585	0.97554	1	0.092509	0.348	0.053409	0.268	0.18508	0.495	0.083249	0.34	0.02179	0.186	0.0223	0.186
MLL3	29 (15%)	165	0.96439	1	0.0453	0.268	0.0096899	0.121	0.02084	0.186	0.051079	0.268	0.02224	0.186	0.02442	0.195	0.83628	0.937	0.62911	0.777	0.61445	0.773
ARID1A	14 (7%)	180	0.0062899	0.0968	0.00427	0.0792	0.65412	0.798	0.12547	0.413	0.16738	0.479	0.00062999	0.046	0.10091	0.354	0.00431	0.0792	0.70217	0.821	0.00475	0.0792
NFE2L2	12 (6%)	182	0.92583	0.996	0.099009	0.354	0.46253	0.685	0.04941	0.268	0.45534	0.685	0.04649	0.268	0.0357	0.234	0.01841	0.186	0.38363	0.656	0.072569	0.317
PIK3CA	53 (27%)	141	0.03449	0.234	0.28194	0.594	0.30414	0.611	0.29795	0.61	0.35148	0.615	0.004	0.0792	0.33149	0.611	0.34544	0.611	0.48121	0.692	0.2316	0.539
CASP8	9 (5%)	185	0.677	0.808	0.47592	0.692	0.18568	0.495	0.16768	0.479	0.22129	0.537	0.45899	0.685	0.56981	0.745	0.45126	0.685	0.12483	0.413	0.43255	0.681
FAT2	11 (6%)	183	0.61466	0.773	0.051889	0.268	0.53864	0.739	0.6265	0.777	0.063989	0.305	0.48034	0.692	0.58552	0.76	0.76218	0.874	0.069379	0.315	0.091499	0.348
ZNF750	9 (5%)	185	0.13219	0.426	0.56128	0.745	0.41997	0.681	0.32091	0.611	0.603	0.773	0.30701	0.611	0.31959	0.611	0.096029	0.349	0.54913	0.739	0.080419	0.335
C12ORF43	4 (2%)	190	0.19914	0.509	0.14464	0.438	NA	NA	NA	NA	0.91202	0.986	0.45186	0.685	0.47322	0.692	0.20568	0.514	0.29231	0.609	0.16242	0.479
C3ORF70	4 (2%)	190	0.54981	0.739	0.34237	0.611	0.37746	0.651	0.17823	0.495	0.65276	0.798	0.12581	0.413	0.18383	0.495	0.2987	0.61	0.32117	0.611	0.12607	0.413
BAP1	4 (2%)	190	0.14008	0.431	0.058969	0.288	NA	NA	NA	NA	0.51019	0.724	0.45361	0.685	0.68894	0.815	0.3536	0.615	0.25853	0.558	0.17232	0.485
USP28	4 (2%)	190	0.19933	0.509	0.54277	0.739	0.66076	0.801	0.91122	0.986	0.60717	0.773	1	1	0.38883	0.659	0.93687	1	0.20098	0.509	0.81836	0.925
IFNGR1	6 (3%)	188	1	1	0.74313	0.859	0.45298	0.685	0.91061	0.986	0.84325	0.937	1	1	0.32681	0.611	0.03295	0.234	0.053529	0.268	0.78638	0.894
