This pipeline computes the correlation between significant arm-level copy number variations (cnvs) and molecular subtypes.
Testing the association between copy number variation 82 arm-level events and 12 molecular subtypes across 528 patients, 455 significant findings detected with P value < 0.05 and Q value < 0.25.
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1p gain cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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1q gain cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', and 'MIRSEQ_CHIERARCHICAL'.
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2p gain cnv correlated to 'CN_CNMF' and 'MRNASEQ_CHIERARCHICAL'.
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2q gain cnv correlated to 'CN_CNMF', 'MRNASEQ_CHIERARCHICAL', and 'MIRSEQ_CHIERARCHICAL'.
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3p gain cnv correlated to 'CN_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', and 'MIRSEQ_CNMF'.
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3q gain cnv correlated to 'MRNA_CNMF', 'MRNA_CHIERARCHICAL', 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CNMF'.
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4p gain cnv correlated to 'RPPA_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', and 'MIRSEQ_CHIERARCHICAL'.
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4q gain cnv correlated to 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', and 'MIRSEQ_CHIERARCHICAL'.
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5p gain cnv correlated to 'CN_CNMF', 'RPPA_CNMF', 'MRNASEQ_CNMF', and 'MRNASEQ_CHIERARCHICAL'.
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5q gain cnv correlated to 'CN_CNMF' and 'RPPA_CNMF'.
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7p gain cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', and 'MIRSEQ_CHIERARCHICAL'.
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7q gain cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', and 'MIRSEQ_CHIERARCHICAL'.
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8p gain cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CNMF'.
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8q gain cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CNMF'.
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9p gain cnv correlated to 'CN_CNMF', 'RPPA_CHIERARCHICAL', and 'MRNASEQ_CHIERARCHICAL'.
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9q gain cnv correlated to 'CN_CNMF', 'RPPA_CHIERARCHICAL', and 'MRNASEQ_CHIERARCHICAL'.
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10p gain cnv correlated to 'CN_CNMF', 'RPPA_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', and 'MIRSEQ_CNMF'.
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10q gain cnv correlated to 'CN_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', and 'MIRSEQ_CNMF'.
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11p gain cnv correlated to 'CN_CNMF'.
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11q gain cnv correlated to 'CN_CNMF'.
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12p gain cnv correlated to 'MRNA_CNMF', 'MRNA_CHIERARCHICAL', 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CNMF'.
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12q gain cnv correlated to 'MRNA_CNMF', 'MRNA_CHIERARCHICAL', 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CNMF'.
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13q gain cnv correlated to 'METHLYATION_CNMF'.
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14q gain cnv correlated to 'CN_CNMF', 'RPPA_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', and 'MIRSEQ_CNMF'.
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15q gain cnv correlated to 'CN_CNMF' and 'RPPA_CHIERARCHICAL'.
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16p gain cnv correlated to 'CN_CNMF', 'RPPA_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', and 'MIRSEQ_CHIERARCHICAL'.
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16q gain cnv correlated to 'CN_CNMF', 'RPPA_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', and 'MIRSEQ_CNMF'.
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17p gain cnv correlated to 'MRNA_CNMF', 'MRNA_CHIERARCHICAL', 'CN_CNMF', 'MRNASEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CNMF'.
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17q gain cnv correlated to 'MRNA_CHIERARCHICAL', 'CN_CNMF', 'MRNASEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CNMF'.
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18p gain cnv correlated to 'MIRSEQ_MATURE_CHIERARCHICAL'.
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18q gain cnv correlated to 'MIRSEQ_MATURE_CHIERARCHICAL'.
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19p gain cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', and 'MIRSEQ_CNMF'.
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19q gain cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', and 'MIRSEQ_CNMF'.
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20p gain cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CNMF'.
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20q gain cnv correlated to 'MRNA_CNMF', 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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21q gain cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', and 'MIRSEQ_CHIERARCHICAL'.
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22q gain cnv correlated to 'CN_CNMF' and 'MRNASEQ_CHIERARCHICAL'.
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xp gain cnv correlated to 'CN_CNMF', 'RPPA_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', and 'MRNASEQ_CHIERARCHICAL'.
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xq gain cnv correlated to 'RPPA_CNMF'.
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1p loss cnv correlated to 'MRNA_CNMF', 'MRNA_CHIERARCHICAL', 'CN_CNMF', 'RPPA_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CNMF'.
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1q loss cnv correlated to 'MRNA_CNMF', 'MRNA_CHIERARCHICAL', 'CN_CNMF', 'RPPA_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', and 'MIRSEQ_CHIERARCHICAL'.
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2p loss cnv correlated to 'MRNA_CNMF', 'MRNA_CHIERARCHICAL', 'CN_CNMF', 'RPPA_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', and 'MIRSEQ_CHIERARCHICAL'.
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2q loss cnv correlated to 'MRNA_CNMF', 'MRNA_CHIERARCHICAL', 'CN_CNMF', 'RPPA_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', and 'MIRSEQ_CHIERARCHICAL'.
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3p loss cnv correlated to 'MRNA_CNMF', 'MRNA_CHIERARCHICAL', 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', and 'MIRSEQ_CHIERARCHICAL'.
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3q loss cnv correlated to 'CN_CNMF', 'MRNASEQ_CHIERARCHICAL', and 'MIRSEQ_CHIERARCHICAL'.
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4p loss cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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4q loss cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', and 'MRNASEQ_CHIERARCHICAL'.
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5p loss cnv correlated to 'CN_CNMF', 'RPPA_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', and 'MIRSEQ_CNMF'.
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5q loss cnv correlated to 'CN_CNMF', 'RPPA_CNMF', 'MRNASEQ_CNMF', and 'MRNASEQ_CHIERARCHICAL'.
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6p loss cnv correlated to 'MRNA_CNMF', 'MRNA_CHIERARCHICAL', 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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6q loss cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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7p loss cnv correlated to 'RPPA_CNMF' and 'RPPA_CHIERARCHICAL'.
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7q loss cnv correlated to 'RPPA_CNMF', 'MRNASEQ_CNMF', and 'MIRSEQ_CNMF'.
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8p loss cnv correlated to 'CN_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', and 'MIRSEQ_CHIERARCHICAL'.
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8q loss cnv correlated to 'METHLYATION_CNMF'.
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9p loss cnv correlated to 'MRNA_CNMF', 'MRNA_CHIERARCHICAL', 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CNMF'.
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9q loss cnv correlated to 'MRNA_CNMF', 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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10p loss cnv correlated to 'CN_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CHIERARCHICAL', and 'MIRSEQ_CNMF'.
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10q loss cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', and 'MIRSEQ_CHIERARCHICAL'.
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11p loss cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', and 'MRNASEQ_CHIERARCHICAL'.
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11q loss cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', and 'MIRSEQ_CHIERARCHICAL'.
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13q loss cnv correlated to 'MRNA_CNMF', 'MRNA_CHIERARCHICAL', 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', and 'MIRSEQ_CHIERARCHICAL'.
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14q loss cnv correlated to 'MRNA_CNMF', 'MRNA_CHIERARCHICAL', 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', and 'MIRSEQ_CHIERARCHICAL'.
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15q loss cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', and 'MIRSEQ_CHIERARCHICAL'.
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16p loss cnv correlated to 'RPPA_CHIERARCHICAL'.
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16q loss cnv correlated to 'CN_CNMF', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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17p loss cnv correlated to 'MRNA_CNMF', 'MRNA_CHIERARCHICAL', 'CN_CNMF', 'RPPA_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', and 'MIRSEQ_CHIERARCHICAL'.
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17q loss cnv correlated to 'MRNA_CNMF', 'MRNA_CHIERARCHICAL', 'CN_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', and 'MIRSEQ_CHIERARCHICAL'.
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18p loss cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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18q loss cnv correlated to 'MRNA_CNMF', 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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19p loss cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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19q loss cnv correlated to 'CN_CNMF'.
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20p loss cnv correlated to 'MIRSEQ_CNMF'.
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20q loss cnv correlated to 'MIRSEQ_CHIERARCHICAL'.
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21q loss cnv correlated to 'MRNA_CNMF', 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', and 'MIRSEQ_CHIERARCHICAL'.
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22q loss cnv correlated to 'MRNA_CNMF', 'MRNA_CHIERARCHICAL', 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CNMF'.
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xp loss cnv correlated to 'MRNA_CNMF', 'CN_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', and 'MIRSEQ_CHIERARCHICAL'.
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xq loss cnv correlated to 'MRNA_CNMF', 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', and 'MIRSEQ_CHIERARCHICAL'.
Table 1. Get Full Table Overview of the association between significant copy number variation of 82 arm-level events and 12 molecular subtypes. Shown in the table are P values (Q values). Thresholded by P value < 0.05 and Q value < 0.25, 455 significant findings detected.
|
Clinical Features |
MRNA CNMF |
MRNA CHIERARCHICAL |
CN CNMF |
METHLYATION CNMF |
RPPA CNMF |
RPPA CHIERARCHICAL |
MRNASEQ CNMF |
MRNASEQ CHIERARCHICAL |
MIRSEQ CNMF |
MIRSEQ CHIERARCHICAL |
MIRSEQ MATURE CNMF |
MIRSEQ MATURE CHIERARCHICAL |
||
| nCNV (%) | nWild-Type | Fisher's exact test | Fisher's exact test | Fisher's exact test | Fisher's exact test | Fisher's exact test | Fisher's exact test | Fisher's exact test | Fisher's exact test | Fisher's exact test | Fisher's exact test | Fisher's exact test | Fisher's exact test | |
| 3q gain | 61 (12%) | 467 |
0.012 (0.0338) |
0.0309 (0.0737) |
1e-05 (6.52e-05) |
0.00365 (0.0122) |
1e-05 (6.52e-05) |
2e-05 (0.000118) |
6e-05 (0.000319) |
2e-05 (0.000118) |
1e-05 (6.52e-05) |
0.0004 (0.00173) |
0.00154 (0.00563) |
0.079 (0.153) |
| 12p gain | 121 (23%) | 407 |
0.0131 (0.0365) |
0.0326 (0.0766) |
1e-05 (6.52e-05) |
1e-05 (6.52e-05) |
1e-05 (6.52e-05) |
2e-05 (0.000118) |
1e-05 (6.52e-05) |
1e-05 (6.52e-05) |
1e-05 (6.52e-05) |
1e-05 (6.52e-05) |
0.00149 (0.00549) |
0.104 (0.19) |
| 12q gain | 122 (23%) | 406 |
0.0132 (0.0368) |
0.0333 (0.078) |
1e-05 (6.52e-05) |
8e-05 (0.000414) |
1e-05 (6.52e-05) |
1e-05 (6.52e-05) |
1e-05 (6.52e-05) |
1e-05 (6.52e-05) |
1e-05 (6.52e-05) |
1e-05 (6.52e-05) |
0.00288 (0.01) |
0.128 (0.221) |
| 20q gain | 115 (22%) | 413 |
0.0429 (0.0957) |
0.0746 (0.147) |
1e-05 (6.52e-05) |
4e-05 (0.000219) |
1e-05 (6.52e-05) |
1e-05 (6.52e-05) |
1e-05 (6.52e-05) |
1e-05 (6.52e-05) |
1e-05 (6.52e-05) |
1e-05 (6.52e-05) |
1e-05 (6.52e-05) |
0.0326 (0.0766) |
| 6p loss | 100 (19%) | 428 |
0.0107 (0.0308) |
0.0141 (0.0387) |
1e-05 (6.52e-05) |
6e-05 (0.000319) |
1e-05 (6.52e-05) |
1e-05 (6.52e-05) |
1e-05 (6.52e-05) |
1e-05 (6.52e-05) |
1e-05 (6.52e-05) |
1e-05 (6.52e-05) |
0.0829 (0.158) |
0.0243 (0.06) |
| 9p loss | 149 (28%) | 379 |
0.00377 (0.0126) |
0.0365 (0.084) |
1e-05 (6.52e-05) |
1e-05 (6.52e-05) |
1e-05 (6.52e-05) |
1e-05 (6.52e-05) |
1e-05 (6.52e-05) |
1e-05 (6.52e-05) |
1e-05 (6.52e-05) |
1e-05 (6.52e-05) |
0.0164 (0.0437) |
0.0984 (0.181) |
| 9q loss | 150 (28%) | 378 |
0.00921 (0.0274) |
0.0585 (0.123) |
1e-05 (6.52e-05) |
1e-05 (6.52e-05) |
1e-05 (6.52e-05) |
1e-05 (6.52e-05) |
1e-05 (6.52e-05) |
1e-05 (6.52e-05) |
1e-05 (6.52e-05) |
1e-05 (6.52e-05) |
0.00357 (0.012) |
0.037 (0.0849) |
| 18q loss | 95 (18%) | 433 |
0.0462 (0.101) |
0.22 (0.335) |
1e-05 (6.52e-05) |
1e-05 (6.52e-05) |
1e-05 (6.52e-05) |
1e-05 (6.52e-05) |
1e-05 (6.52e-05) |
1e-05 (6.52e-05) |
1e-05 (6.52e-05) |
1e-05 (6.52e-05) |
0.00336 (0.0114) |
0.0308 (0.0736) |
| 22q loss | 39 (7%) | 489 |
0.00982 (0.0287) |
0.00138 (0.0052) |
1e-05 (6.52e-05) |
0.00354 (0.0119) |
0.00037 (0.00163) |
0.0204 (0.0523) |
1e-05 (6.52e-05) |
2e-05 (0.000118) |
1e-05 (6.52e-05) |
0.00341 (0.0115) |
0.0254 (0.0625) |
0.259 (0.376) |
| 3p loss | 380 (72%) | 148 |
0.003 (0.0104) |
0.0103 (0.0299) |
1e-05 (6.52e-05) |
0.00068 (0.00276) |
0.0122 (0.0344) |
0.00034 (0.00153) |
1e-05 (6.52e-05) |
1e-05 (6.52e-05) |
0.0227 (0.057) |
0.0086 (0.026) |
0.0916 (0.171) |
0.733 (0.873) |
| 13q loss | 71 (13%) | 457 |
0.0033 (0.0113) |
0.0468 (0.102) |
1e-05 (6.52e-05) |
0.00023 (0.00109) |
1e-05 (6.52e-05) |
2e-05 (0.000118) |
1e-05 (6.52e-05) |
1e-05 (6.52e-05) |
1e-05 (6.52e-05) |
1e-05 (6.52e-05) |
0.107 (0.192) |
0.103 (0.189) |
| 14q loss | 216 (41%) | 312 |
4e-05 (0.000219) |
1e-05 (6.52e-05) |
1e-05 (6.52e-05) |
1e-05 (6.52e-05) |
1e-05 (6.52e-05) |
0.0139 (0.0385) |
1e-05 (6.52e-05) |
1e-05 (6.52e-05) |
1e-05 (6.52e-05) |
1e-05 (6.52e-05) |
0.0506 (0.109) |
0.88 (1.00) |
| 18p loss | 93 (18%) | 435 |
0.0586 (0.123) |
0.459 (0.591) |
1e-05 (6.52e-05) |
1e-05 (6.52e-05) |
1e-05 (6.52e-05) |
1e-05 (6.52e-05) |
1e-05 (6.52e-05) |
1e-05 (6.52e-05) |
1e-05 (6.52e-05) |
1e-05 (6.52e-05) |
0.00025 (0.00115) |
0.0045 (0.0146) |
| 8p gain | 31 (6%) | 497 |
1e-05 (6.52e-05) |
0.00042 (0.0018) |
0.00044 (0.00188) |
1e-05 (6.52e-05) |
1e-05 (6.52e-05) |
2e-05 (0.000118) |
1e-05 (6.52e-05) |
0.00477 (0.0154) |
0.0116 (0.033) |
0.105 (0.19) |
||
| 8q gain | 62 (12%) | 466 |
0.227 (0.341) |
0.105 (0.19) |
1e-05 (6.52e-05) |
1e-05 (6.52e-05) |
1e-05 (6.52e-05) |
1e-05 (6.52e-05) |
1e-05 (6.52e-05) |
1e-05 (6.52e-05) |
1e-05 (6.52e-05) |
0.00014 (0.000689) |
0.00047 (0.00198) |
0.408 (0.545) |
| 20p gain | 112 (21%) | 416 |
0.117 (0.204) |
0.116 (0.204) |
1e-05 (6.52e-05) |
2e-05 (0.000118) |
1e-05 (6.52e-05) |
1e-05 (6.52e-05) |
1e-05 (6.52e-05) |
1e-05 (6.52e-05) |
1e-05 (6.52e-05) |
1e-05 (6.52e-05) |
2e-05 (0.000118) |
0.053 (0.113) |
| 1p loss | 57 (11%) | 471 |
0.00085 (0.00336) |
0.00273 (0.00959) |
1e-05 (6.52e-05) |
0.675 (0.816) |
0.00748 (0.0227) |
0.0193 (0.0497) |
0.116 (0.204) |
4e-05 (0.000219) |
0.00796 (0.0241) |
0.0233 (0.058) |
0.0356 (0.0822) |
0.824 (0.953) |
| 1q loss | 36 (7%) | 492 |
0.0102 (0.0296) |
0.0111 (0.0317) |
1e-05 (6.52e-05) |
0.369 (0.502) |
0.0362 (0.0834) |
0.00265 (0.00935) |
0.00449 (0.0146) |
1e-05 (6.52e-05) |
0.00589 (0.0184) |
0.042 (0.0942) |
0.223 (0.338) |
0.708 (0.846) |
| 2p loss | 14 (3%) | 514 |
4e-05 (0.000219) |
0.00061 (0.00251) |
1e-05 (6.52e-05) |
0.662 (0.805) |
0.00079 (0.00316) |
0.0002 (0.000969) |
1e-05 (6.52e-05) |
1e-05 (6.52e-05) |
2e-05 (0.000118) |
4e-05 (0.000219) |
0.131 (0.224) |
0.0969 (0.179) |
| 2q loss | 14 (3%) | 514 |
0.00028 (0.00128) |
0.00086 (0.00338) |
1e-05 (6.52e-05) |
1 (1.00) |
0.00295 (0.0103) |
0.00024 (0.00112) |
1e-05 (6.52e-05) |
1e-05 (6.52e-05) |
1e-05 (6.52e-05) |
2e-05 (0.000118) |
0.132 (0.225) |
0.0962 (0.178) |
| 6q loss | 128 (24%) | 400 |
0.0507 (0.109) |
0.0521 (0.112) |
1e-05 (6.52e-05) |
0.00577 (0.0181) |
1e-05 (6.52e-05) |
1e-05 (6.52e-05) |
0.00025 (0.00115) |
8e-05 (0.000414) |
1e-05 (6.52e-05) |
4e-05 (0.000219) |
0.168 (0.273) |
0.0259 (0.0633) |
| 17p loss | 46 (9%) | 482 |
7e-05 (0.000368) |
0.00024 (0.00112) |
1e-05 (6.52e-05) |
0.0886 (0.167) |
0.00045 (0.00191) |
1e-05 (6.52e-05) |
1e-05 (6.52e-05) |
1e-05 (6.52e-05) |
1e-05 (6.52e-05) |
0.00022 (0.00106) |
0.202 (0.315) |
0.0856 (0.163) |
| 21q loss | 55 (10%) | 473 |
0.0256 (0.0629) |
0.0885 (0.167) |
1e-05 (6.52e-05) |
0.0137 (0.0379) |
0.00074 (0.003) |
1e-05 (6.52e-05) |
0.00324 (0.0111) |
0.0001 (0.00051) |
0.00694 (0.0213) |
0.0093 (0.0276) |
0.884 (1.00) |
1 (1.00) |
| 7p gain | 171 (32%) | 357 |
0.452 (0.586) |
0.859 (0.984) |
1e-05 (6.52e-05) |
0.00147 (0.00544) |
1e-05 (6.52e-05) |
4e-05 (0.000219) |
5e-05 (0.000269) |
0.00953 (0.0281) |
0.00411 (0.0135) |
0.031 (0.0737) |
0.102 (0.187) |
0.766 (0.905) |
| 7q gain | 172 (33%) | 356 |
0.451 (0.585) |
0.859 (0.984) |
1e-05 (6.52e-05) |
0.00405 (0.0134) |
3e-05 (0.000173) |
2e-05 (0.000118) |
8e-05 (0.000414) |
0.007 (0.0214) |
0.00516 (0.0165) |
0.0178 (0.0467) |
0.174 (0.279) |
0.589 (0.727) |
| 17q loss | 28 (5%) | 500 |
0.00051 (0.00214) |
0.00032 (0.00145) |
1e-05 (6.52e-05) |
0.582 (0.721) |
0.156 (0.257) |
0.00278 (0.00973) |
7e-05 (0.000368) |
1e-05 (6.52e-05) |
1e-05 (6.52e-05) |
0.00512 (0.0164) |
0.456 (0.588) |
0.15 (0.251) |
| 19p loss | 11 (2%) | 517 |
2e-05 (0.000118) |
0.0322 (0.0759) |
0.00015 (0.000734) |
0.00177 (0.00636) |
0.168 (0.273) |
0.0108 (0.031) |
0.24 (0.354) |
0.00939 (0.0277) |
0.0335 (0.0782) |
0.0374 (0.0853) |
||
| 1p gain | 24 (5%) | 504 |
0.82 (0.949) |
0.925 (1.00) |
1e-05 (6.52e-05) |
0.00059 (0.00244) |
0.176 (0.281) |
0.393 (0.529) |
0.00088 (0.00345) |
0.00139 (0.0052) |
0.00176 (0.00634) |
0.0065 (0.0202) |
0.752 (0.891) |
0.0391 (0.0885) |
| 19p gain | 51 (10%) | 477 |
0.223 (0.338) |
0.484 (0.617) |
1e-05 (6.52e-05) |
5e-05 (0.000269) |
0.00146 (0.00542) |
0.0127 (0.0356) |
0.00163 (0.00594) |
0.00078 (0.00313) |
3e-05 (0.000173) |
0.356 (0.486) |
0.921 (1.00) |
0.626 (0.766) |
| 19q gain | 57 (11%) | 471 |
0.103 (0.188) |
0.224 (0.338) |
1e-05 (6.52e-05) |
4e-05 (0.000219) |
2e-05 (0.000118) |
0.00064 (0.00262) |
0.00059 (0.00244) |
9e-05 (0.000461) |
1e-05 (6.52e-05) |
0.17 (0.275) |
0.582 (0.721) |
0.287 (0.409) |
| 11q loss | 23 (4%) | 505 |
0.189 (0.297) |
0.374 (0.508) |
1e-05 (6.52e-05) |
0.00553 (0.0176) |
0.162 (0.266) |
0.00966 (0.0284) |
0.014 (0.0385) |
0.00039 (0.0017) |
0.0229 (0.0574) |
0.0378 (0.0861) |
0.3 (0.421) |
0.309 (0.432) |
| 15q loss | 36 (7%) | 492 |
0.117 (0.204) |
0.334 (0.461) |
1e-05 (6.52e-05) |
0.00068 (0.00276) |
0.0618 (0.129) |
0.00969 (0.0284) |
1e-05 (6.52e-05) |
1e-05 (6.52e-05) |
0.00089 (0.00348) |
0.016 (0.043) |
0.0703 (0.142) |
0.131 (0.223) |
| 1q gain | 51 (10%) | 477 |
0.41 (0.545) |
0.901 (1.00) |
1e-05 (6.52e-05) |
0.0139 (0.0385) |
0.149 (0.25) |
0.207 (0.32) |
1e-05 (6.52e-05) |
0.00175 (0.00633) |
3e-05 (0.000173) |
0.00567 (0.0179) |
0.421 (0.557) |
0.758 (0.898) |
| 4p gain | 13 (2%) | 515 |
0.0723 (0.144) |
0.374 (0.508) |
0.0373 (0.0853) |
5e-05 (0.000269) |
0.00038 (0.00166) |
0.00041 (0.00177) |
0.00023 (0.00109) |
0.0448 (0.098) |
||||
| 14q gain | 16 (3%) | 512 |
0.77 (0.908) |
0.572 (0.711) |
0.00119 (0.00456) |
0.35 (0.48) |
0.00191 (0.00681) |
0.0334 (0.078) |
0.00694 (0.0213) |
0.00034 (0.00153) |
0.00403 (0.0134) |
0.113 (0.2) |
||
| 21q gain | 50 (9%) | 478 |
0.27 (0.389) |
0.208 (0.32) |
1e-05 (6.52e-05) |
0.00133 (0.00503) |
0.162 (0.266) |
0.0629 (0.13) |
0.00025 (0.00115) |
0.00322 (0.0111) |
0.00315 (0.0109) |
0.0311 (0.0738) |
0.351 (0.48) |
0.474 (0.606) |
| 4p loss | 72 (14%) | 456 |
0.532 (0.669) |
0.816 (0.947) |
1e-05 (6.52e-05) |
0.00012 (0.000602) |
0.00058 (0.00242) |
0.0581 (0.122) |
0.00083 (0.00329) |
0.00125 (0.00475) |
0.568 (0.707) |
0.0708 (0.142) |
0.0788 (0.153) |
0.00695 (0.0213) |
| 4q loss | 65 (12%) | 463 |
0.386 (0.522) |
0.785 (0.919) |
1e-05 (6.52e-05) |
2e-05 (0.000118) |
0.00036 (0.0016) |
0.017 (0.045) |
0.00038 (0.00166) |
3e-05 (0.000173) |
0.198 (0.31) |
0.0641 (0.132) |
0.429 (0.566) |
0.0565 (0.12) |
| 10q loss | 89 (17%) | 439 |
0.331 (0.458) |
0.4 (0.536) |
1e-05 (6.52e-05) |
0.00421 (0.0138) |
0.819 (0.949) |
0.0222 (0.0563) |
0.122 (0.212) |
0.00198 (0.00703) |
0.0383 (0.0869) |
0.0005 (0.0021) |
0.804 (0.937) |
0.436 (0.572) |
| xq loss | 46 (9%) | 482 |
0.0241 (0.0597) |
0.0628 (0.13) |
1e-05 (6.52e-05) |
0.00897 (0.0268) |
0.597 (0.736) |
0.0508 (0.109) |
0.0914 (0.171) |
0.0281 (0.0674) |
0.018 (0.0471) |
0.00334 (0.0114) |
0.229 (0.343) |
0.175 (0.279) |
| 3p gain | 19 (4%) | 509 |
0.0542 (0.116) |
0.433 (0.569) |
0.00037 (0.00163) |
0.579 (0.719) |
0.178 (0.284) |
0.00045 (0.00191) |
0.009 (0.0268) |
0.00014 (0.000689) |
0.00014 (0.000689) |
0.125 (0.217) |
0.392 (0.528) |
0.736 (0.875) |
| 4q gain | 13 (2%) | 515 |
0.214 (0.327) |
0.456 (0.588) |
0.272 (0.39) |
0.0015 (0.00551) |
0.00032 (0.00145) |
0.00435 (0.0142) |
0.00021 (0.00101) |
0.0442 (0.0971) |
||||
| 10p gain | 17 (3%) | 511 |
0.00024 (0.00112) |
0.255 (0.373) |
0.0239 (0.0594) |
0.0784 (0.153) |
0.00091 (0.00353) |
0.00017 (0.000828) |
0.0186 (0.0483) |
0.0682 (0.139) |
||||
| 16p gain | 107 (20%) | 421 |
0.273 (0.391) |
0.379 (0.514) |
9e-05 (0.000461) |
0.168 (0.273) |
0.0215 (0.0549) |
0.181 (0.286) |
0.00671 (0.0208) |
0.00438 (0.0143) |
0.0603 (0.126) |
0.0259 (0.0633) |
0.129 (0.221) |
0.394 (0.529) |
| 16q gain | 99 (19%) | 429 |
0.234 (0.347) |
0.351 (0.48) |
4e-05 (0.000219) |
0.0881 (0.167) |
0.00558 (0.0177) |
0.0922 (0.171) |
0.00626 (0.0195) |
0.016 (0.043) |
0.0162 (0.0434) |
0.147 (0.247) |
0.18 (0.286) |
0.266 (0.385) |
| 17p gain | 26 (5%) | 502 |
0.0181 (0.0472) |
0.00532 (0.0169) |
2e-05 (0.000118) |
0.816 (0.947) |
0.135 (0.229) |
0.101 (0.186) |
0.15 (0.251) |
0.00497 (0.016) |
0.147 (0.247) |
0.263 (0.381) |
0.0346 (0.08) |
0.735 (0.874) |
| xp gain | 32 (6%) | 496 |
1 (1.00) |
0.527 (0.664) |
0.00586 (0.0184) |
0.225 (0.339) |
0.00012 (0.000602) |
0.0011 (0.00423) |
0.016 (0.043) |
0.00091 (0.00353) |
0.128 (0.22) |
0.142 (0.241) |
0.556 (0.695) |
0.901 (1.00) |
| 5p loss | 7 (1%) | 521 |
0.0163 (0.0436) |
0.287 (0.409) |
0.0102 (0.0296) |
0.0783 (0.153) |
0.0265 (0.0642) |
0.011 (0.0316) |
0.0423 (0.0945) |
0.0656 (0.134) |
||||
| xp loss | 46 (9%) | 482 |
0.0433 (0.0961) |
0.0663 (0.135) |
0.00013 (0.000649) |
0.0718 (0.143) |
0.464 (0.595) |
0.24 (0.354) |
0.207 (0.32) |
0.0123 (0.0345) |
0.0398 (0.0899) |
0.00094 (0.00363) |
0.109 (0.195) |
0.161 (0.264) |
| 5p gain | 193 (37%) | 335 |
0.883 (1.00) |
0.924 (1.00) |
0.00036 (0.0016) |
0.259 (0.377) |
0.0186 (0.0483) |
0.891 (1.00) |
0.00864 (0.026) |
0.0217 (0.0554) |
0.0689 (0.139) |
0.152 (0.252) |
0.0829 (0.158) |
0.906 (1.00) |
| 10q gain | 12 (2%) | 516 |
0.00012 (0.000602) |
0.117 (0.204) |
0.0573 (0.121) |
0.0923 (0.171) |
0.014 (0.0385) |
0.00182 (0.00651) |
0.0154 (0.0419) |
0.213 (0.327) |
||||
| 17q gain | 33 (6%) | 495 |
0.0703 (0.142) |
0.026 (0.0633) |
1e-05 (6.52e-05) |
0.238 (0.353) |
0.115 (0.204) |
0.223 (0.338) |
0.076 (0.149) |
0.00167 (0.00606) |
0.0786 (0.153) |
0.222 (0.338) |
0.0021 (0.00743) |
0.297 (0.419) |
| 5q loss | 6 (1%) | 522 |
0.0432 (0.096) |
0.542 (0.679) |
0.0432 (0.096) |
0.224 (0.339) |
0.0458 (0.0999) |
0.0151 (0.0411) |
0.0728 (0.144) |
0.0947 (0.175) |
||||
| 8p loss | 137 (26%) | 391 |
0.381 (0.515) |
0.165 (0.269) |
1e-05 (6.52e-05) |
0.28 (0.4) |
0.0729 (0.144) |
0.977 (1.00) |
0.0829 (0.158) |
0.00124 (0.00473) |
0.0417 (0.094) |
0.0231 (0.0578) |
0.274 (0.392) |
0.243 (0.357) |
| 10p loss | 67 (13%) | 461 |
0.175 (0.279) |
0.404 (0.54) |
1e-05 (6.52e-05) |
0.0808 (0.156) |
0.461 (0.592) |
0.0226 (0.0569) |
0.153 (0.254) |
0.0008 (0.00319) |
0.017 (0.045) |
0.109 (0.195) |
0.776 (0.913) |
0.296 (0.418) |
| 2q gain | 79 (15%) | 449 |
0.562 (0.701) |
0.267 (0.386) |
1e-05 (6.52e-05) |
0.165 (0.27) |
0.18 (0.286) |
0.668 (0.812) |
0.23 (0.344) |
0.0173 (0.0456) |
0.708 (0.846) |
0.0252 (0.0622) |
0.32 (0.445) |
0.652 (0.794) |
| 9p gain | 13 (2%) | 515 |
0.0152 (0.0412) |
0.902 (1.00) |
0.51 (0.648) |
0.0342 (0.0795) |
0.248 (0.363) |
0.0176 (0.0463) |
1 (1.00) |
0.861 (0.985) |
1 (1.00) |
1 (1.00) |
||
| 9q gain | 12 (2%) | 516 |
0.00139 (0.0052) |
0.909 (1.00) |
0.25 (0.365) |
0.0316 (0.0747) |
0.241 (0.354) |
0.0262 (0.0638) |
0.531 (0.669) |
0.67 (0.813) |
1 (1.00) |
1 (1.00) |
||
| 3q loss | 99 (19%) | 429 |
0.923 (1.00) |
0.513 (0.65) |
0.00143 (0.00533) |
0.403 (0.54) |
0.19 (0.299) |
0.174 (0.279) |
0.129 (0.221) |
0.0192 (0.0497) |
0.651 (0.794) |
0.0273 (0.0659) |
0.802 (0.937) |
0.863 (0.986) |
| 7q loss | 4 (1%) | 524 |
0.122 (0.212) |
0.344 (0.473) |
0.0107 (0.0308) |
0.0563 (0.12) |
0.0495 (0.107) |
0.0788 (0.153) |
0.0193 (0.0497) |
0.773 (0.912) |
||||
| 11p loss | 18 (3%) | 510 |
1e-05 (6.52e-05) |
0.0223 (0.0565) |
0.434 (0.57) |
0.105 (0.19) |
0.171 (0.275) |
0.0273 (0.0659) |
0.171 (0.275) |
0.149 (0.25) |
0.3 (0.421) |
0.31 (0.433) |
||
| 16q loss | 16 (3%) | 512 |
0.0379 (0.0861) |
0.909 (1.00) |
0.295 (0.417) |
0.432 (0.568) |
0.106 (0.192) |
0.0898 (0.169) |
0.0648 (0.133) |
0.00867 (0.026) |
0.0707 (0.142) |
0.028 (0.0674) |
||
| 2p gain | 77 (15%) | 451 |
0.701 (0.841) |
0.458 (0.59) |
1e-05 (6.52e-05) |
0.0824 (0.158) |
0.0736 (0.146) |
0.777 (0.913) |
0.232 (0.346) |
0.0118 (0.0334) |
0.621 (0.76) |
0.143 (0.242) |
0.229 (0.343) |
0.47 (0.601) |
| 5q gain | 207 (39%) | 321 |
0.334 (0.461) |
0.626 (0.766) |
0.0225 (0.0568) |
0.439 (0.573) |
0.00708 (0.0216) |
0.797 (0.932) |
0.0567 (0.12) |
0.0686 (0.139) |
0.448 (0.583) |
0.207 (0.32) |
0.129 (0.221) |
0.906 (1.00) |
| 15q gain | 26 (5%) | 502 |
1 (1.00) |
0.117 (0.204) |
0.00077 (0.00311) |
0.724 (0.864) |
0.0914 (0.171) |
0.00385 (0.0128) |
0.672 (0.813) |
0.106 (0.191) |
0.706 (0.846) |
0.412 (0.547) |
0.684 (0.822) |
0.827 (0.955) |
| 22q gain | 40 (8%) | 488 |
0.327 (0.454) |
0.219 (0.335) |
2e-05 (0.000118) |
0.209 (0.321) |
0.534 (0.67) |
0.292 (0.414) |
0.0547 (0.117) |
0.0164 (0.0436) |
0.0621 (0.129) |
0.412 (0.547) |
0.91 (1.00) |
0.306 (0.43) |
| 7p loss | 3 (1%) | 525 |
0.166 (0.271) |
0.0445 (0.0976) |
0.042 (0.0942) |
0.107 (0.193) |
0.169 (0.273) |
0.0574 (0.121) |
0.355 (0.485) |
|||||
| 11p gain | 31 (6%) | 497 |
0.231 (0.345) |
0.671 (0.813) |
1e-05 (6.52e-05) |
0.271 (0.39) |
0.0726 (0.144) |
0.514 (0.65) |
0.152 (0.253) |
0.239 (0.353) |
0.146 (0.246) |
0.281 (0.401) |
0.392 (0.528) |
0.854 (0.982) |
| 11q gain | 29 (5%) | 499 |
0.342 (0.471) |
0.906 (1.00) |
0.00023 (0.00109) |
0.528 (0.666) |
0.138 (0.234) |
0.828 (0.956) |
0.422 (0.557) |
0.573 (0.712) |
0.364 (0.496) |
0.186 (0.293) |
0.751 (0.891) |
0.679 (0.819) |
| 13q gain | 22 (4%) | 506 |
0.487 (0.62) |
0.0344 (0.0798) |
0.227 (0.342) |
0.431 (0.568) |
0.0707 (0.142) |
0.12 (0.21) |
0.345 (0.474) |
0.263 (0.381) |
0.285 (0.406) |
0.323 (0.449) |
||
| 18p gain | 25 (5%) | 503 |
0.313 (0.436) |
0.0765 (0.15) |
0.0749 (0.147) |
0.448 (0.583) |
0.904 (1.00) |
0.522 (0.66) |
0.191 (0.299) |
0.421 (0.557) |
0.835 (0.961) |
0.454 (0.588) |
0.202 (0.315) |
0.0442 (0.0971) |
| 18q gain | 25 (5%) | 503 |
0.313 (0.436) |
0.076 (0.149) |
0.0678 (0.138) |
0.558 (0.697) |
0.764 (0.904) |
0.549 (0.688) |
0.188 (0.297) |
0.42 (0.557) |
0.965 (1.00) |
0.452 (0.585) |
0.202 (0.315) |
0.0441 (0.0971) |
| xq gain | 31 (6%) | 497 |
0.39 (0.526) |
0.701 (0.841) |
0.222 (0.338) |
0.292 (0.414) |
0.0226 (0.0569) |
0.0692 (0.14) |
0.154 (0.255) |
0.102 (0.188) |
0.323 (0.449) |
0.6 (0.739) |
0.918 (1.00) |
0.811 (0.944) |
| 8q loss | 64 (12%) | 464 |
0.647 (0.79) |
0.126 (0.219) |
0.122 (0.212) |
0.0439 (0.0971) |
0.0649 (0.133) |
0.439 (0.573) |
0.722 (0.862) |
0.19 (0.298) |
0.589 (0.727) |
0.409 (0.545) |
0.682 (0.821) |
0.0893 (0.168) |
| 16p loss | 10 (2%) | 518 |
0.204 (0.318) |
0.877 (1.00) |
0.127 (0.219) |
0.0487 (0.105) |
0.293 (0.415) |
0.0624 (0.129) |
0.0918 (0.171) |
0.116 (0.204) |
0.117 (0.204) |
0.116 (0.204) |
||
| 19q loss | 4 (1%) | 524 |
0.0118 (0.0334) |
0.262 (0.38) |
0.256 (0.374) |
0.437 (0.572) |
0.513 (0.65) |
0.833 (0.96) |
0.082 (0.158) |
|||||
| 20p loss | 8 (2%) | 520 |
0.172 (0.276) |
1 (1.00) |
0.257 (0.374) |
0.499 (0.634) |
0.0904 (0.17) |
0.233 (0.346) |
0.0193 (0.0497) |
0.233 (0.346) |
||||
| 20q loss | 3 (1%) | 525 |
0.165 (0.269) |
0.108 (0.194) |
0.154 (0.255) |
0.0592 (0.124) |
0.0294 (0.0704) |
|||||||
| 6p gain | 11 (2%) | 517 |
0.152 (0.253) |
0.445 (0.58) |
0.217 (0.332) |
0.951 (1.00) |
0.794 (0.929) |
0.984 (1.00) |
0.859 (0.984) |
0.111 (0.199) |
0.606 (0.744) |
0.78 (0.915) |
||
| 6q gain | 9 (2%) | 519 |
0.0837 (0.16) |
0.679 (0.819) |
0.109 (0.195) |
0.806 (0.939) |
1 (1.00) |
0.911 (1.00) |
1 (1.00) |
0.183 (0.289) |
0.603 (0.742) |
0.779 (0.915) |
||
| 12p loss | 4 (1%) | 524 |
0.0858 (0.163) |
0.206 (0.32) |
0.469 (0.601) |
0.295 (0.417) |
0.144 (0.243) |
|||||||
| 12q loss | 4 (1%) | 524 |
0.483 (0.617) |
0.209 (0.322) |
0.88 (1.00) |
1 (1.00) |
1 (1.00) |
0.233 (0.346) |
0.613 (0.752) |
P value = 1e-05 (Fisher's exact test), Q value = 6.5e-05
Table S1. Gene #1: '1p gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 238 | 135 | 155 |
| 1P GAIN MUTATED | 2 | 1 | 21 |
| 1P GAIN WILD-TYPE | 236 | 134 | 134 |
Figure S1. Get High-res Image Gene #1: '1p gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.00059 (Fisher's exact test), Q value = 0.0024
Table S2. Gene #1: '1p gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 128 | 76 | 110 |
| 1P GAIN MUTATED | 0 | 7 | 4 |
| 1P GAIN WILD-TYPE | 128 | 69 | 106 |
Figure S2. Get High-res Image Gene #1: '1p gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.00088 (Fisher's exact test), Q value = 0.0034
Table S3. Gene #1: '1p gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 111 | 221 | 193 |
| 1P GAIN MUTATED | 1 | 5 | 17 |
| 1P GAIN WILD-TYPE | 110 | 216 | 176 |
Figure S3. Get High-res Image Gene #1: '1p gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 0.00139 (Fisher's exact test), Q value = 0.0052
Table S4. Gene #1: '1p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 117 | 33 | 183 | 132 | 35 | 25 |
| 1P GAIN MUTATED | 1 | 1 | 4 | 13 | 4 | 0 |
| 1P GAIN WILD-TYPE | 116 | 32 | 179 | 119 | 31 | 25 |
Figure S4. Get High-res Image Gene #1: '1p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00176 (Fisher's exact test), Q value = 0.0063
Table S5. Gene #1: '1p gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 124 | 204 | 182 |
| 1P GAIN MUTATED | 2 | 5 | 17 |
| 1P GAIN WILD-TYPE | 122 | 199 | 165 |
Figure S5. Get High-res Image Gene #1: '1p gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.0065 (Fisher's exact test), Q value = 0.02
Table S6. Gene #1: '1p gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 144 | 134 | 195 | 37 |
| 1P GAIN MUTATED | 7 | 9 | 3 | 5 |
| 1P GAIN WILD-TYPE | 137 | 125 | 192 | 32 |
Figure S6. Get High-res Image Gene #1: '1p gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0391 (Fisher's exact test), Q value = 0.088
Table S7. Gene #1: '1p gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 39 | 56 | 47 |
| 1P GAIN MUTATED | 0 | 4 | 0 |
| 1P GAIN WILD-TYPE | 39 | 52 | 47 |
Figure S7. Get High-res Image Gene #1: '1p gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 6.5e-05
Table S8. Gene #2: '1q gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 238 | 135 | 155 |
| 1Q GAIN MUTATED | 6 | 2 | 43 |
| 1Q GAIN WILD-TYPE | 232 | 133 | 112 |
Figure S8. Get High-res Image Gene #2: '1q gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.0139 (Fisher's exact test), Q value = 0.038
Table S9. Gene #2: '1q gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 128 | 76 | 110 |
| 1Q GAIN MUTATED | 4 | 10 | 11 |
| 1Q GAIN WILD-TYPE | 124 | 66 | 99 |
Figure S9. Get High-res Image Gene #2: '1q gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 6.5e-05
Table S10. Gene #2: '1q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 111 | 221 | 193 |
| 1Q GAIN MUTATED | 1 | 15 | 33 |
| 1Q GAIN WILD-TYPE | 110 | 206 | 160 |
Figure S10. Get High-res Image Gene #2: '1q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 0.00175 (Fisher's exact test), Q value = 0.0063
Table S11. Gene #2: '1q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 117 | 33 | 183 | 132 | 35 | 25 |
| 1Q GAIN MUTATED | 4 | 2 | 15 | 22 | 6 | 0 |
| 1Q GAIN WILD-TYPE | 113 | 31 | 168 | 110 | 29 | 25 |
Figure S11. Get High-res Image Gene #2: '1q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 3e-05 (Fisher's exact test), Q value = 0.00017
Table S12. Gene #2: '1q gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 124 | 204 | 182 |
| 1Q GAIN MUTATED | 3 | 13 | 33 |
| 1Q GAIN WILD-TYPE | 121 | 191 | 149 |
Figure S12. Get High-res Image Gene #2: '1q gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.00567 (Fisher's exact test), Q value = 0.018
Table S13. Gene #2: '1q gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 144 | 134 | 195 | 37 |
| 1Q GAIN MUTATED | 11 | 17 | 12 | 9 |
| 1Q GAIN WILD-TYPE | 133 | 117 | 183 | 28 |
Figure S13. Get High-res Image Gene #2: '1q gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 6.5e-05
Table S14. Gene #3: '2p gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 238 | 135 | 155 |
| 2P GAIN MUTATED | 15 | 14 | 48 |
| 2P GAIN WILD-TYPE | 223 | 121 | 107 |
Figure S14. Get High-res Image Gene #3: '2p gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.0118 (Fisher's exact test), Q value = 0.033
Table S15. Gene #3: '2p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 117 | 33 | 183 | 132 | 35 | 25 |
| 2P GAIN MUTATED | 13 | 2 | 29 | 29 | 3 | 0 |
| 2P GAIN WILD-TYPE | 104 | 31 | 154 | 103 | 32 | 25 |
Figure S15. Get High-res Image Gene #3: '2p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 6.5e-05
Table S16. Gene #4: '2q gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 238 | 135 | 155 |
| 2Q GAIN MUTATED | 18 | 14 | 47 |
| 2Q GAIN WILD-TYPE | 220 | 121 | 108 |
Figure S16. Get High-res Image Gene #4: '2q gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.0173 (Fisher's exact test), Q value = 0.046
Table S17. Gene #4: '2q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 117 | 33 | 183 | 132 | 35 | 25 |
| 2Q GAIN MUTATED | 13 | 2 | 32 | 28 | 4 | 0 |
| 2Q GAIN WILD-TYPE | 104 | 31 | 151 | 104 | 31 | 25 |
Figure S17. Get High-res Image Gene #4: '2q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0252 (Fisher's exact test), Q value = 0.062
Table S18. Gene #4: '2q gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 144 | 134 | 195 | 37 |
| 2Q GAIN MUTATED | 25 | 11 | 38 | 4 |
| 2Q GAIN WILD-TYPE | 119 | 123 | 157 | 33 |
Figure S18. Get High-res Image Gene #4: '2q gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00037 (Fisher's exact test), Q value = 0.0016
Table S19. Gene #5: '3p gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 238 | 135 | 155 |
| 3P GAIN MUTATED | 1 | 9 | 9 |
| 3P GAIN WILD-TYPE | 237 | 126 | 146 |
Figure S19. Get High-res Image Gene #5: '3p gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.00045 (Fisher's exact test), Q value = 0.0019
Table S20. Gene #5: '3p gain' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 135 | 112 | 85 | 139 |
| 3P GAIN MUTATED | 1 | 3 | 10 | 3 |
| 3P GAIN WILD-TYPE | 134 | 109 | 75 | 136 |
Figure S20. Get High-res Image Gene #5: '3p gain' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
P value = 0.009 (Fisher's exact test), Q value = 0.027
Table S21. Gene #5: '3p gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 111 | 221 | 193 |
| 3P GAIN MUTATED | 6 | 2 | 11 |
| 3P GAIN WILD-TYPE | 105 | 219 | 182 |
Figure S21. Get High-res Image Gene #5: '3p gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 0.00014 (Fisher's exact test), Q value = 0.00069
Table S22. Gene #5: '3p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 117 | 33 | 183 | 132 | 35 | 25 |
| 3P GAIN MUTATED | 0 | 2 | 2 | 9 | 2 | 4 |
| 3P GAIN WILD-TYPE | 117 | 31 | 181 | 123 | 33 | 21 |
Figure S22. Get High-res Image Gene #5: '3p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00014 (Fisher's exact test), Q value = 0.00069
Table S23. Gene #5: '3p gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 124 | 204 | 182 |
| 3P GAIN MUTATED | 3 | 1 | 15 |
| 3P GAIN WILD-TYPE | 121 | 203 | 167 |
Figure S23. Get High-res Image Gene #5: '3p gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.012 (Fisher's exact test), Q value = 0.034
Table S24. Gene #6: '3q gain' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 33 | 24 | 13 |
| 3Q GAIN MUTATED | 1 | 7 | 2 |
| 3Q GAIN WILD-TYPE | 32 | 17 | 11 |
Figure S24. Get High-res Image Gene #6: '3q gain' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 0.0309 (Fisher's exact test), Q value = 0.074
Table S25. Gene #6: '3q gain' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 11 | 12 | 4 | 11 | 13 | 9 | 10 |
| 3Q GAIN MUTATED | 0 | 2 | 0 | 5 | 0 | 1 | 2 |
| 3Q GAIN WILD-TYPE | 11 | 10 | 4 | 6 | 13 | 8 | 8 |
Figure S25. Get High-res Image Gene #6: '3q gain' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 6.5e-05
Table S26. Gene #6: '3q gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 238 | 135 | 155 |
| 3Q GAIN MUTATED | 7 | 15 | 39 |
| 3Q GAIN WILD-TYPE | 231 | 120 | 116 |
Figure S26. Get High-res Image Gene #6: '3q gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.00365 (Fisher's exact test), Q value = 0.012
Table S27. Gene #6: '3q gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 128 | 76 | 110 |
| 3Q GAIN MUTATED | 6 | 8 | 20 |
| 3Q GAIN WILD-TYPE | 122 | 68 | 90 |
Figure S27. Get High-res Image Gene #6: '3q gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 6.5e-05
Table S28. Gene #6: '3q gain' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 88 | 86 | 90 | 82 | 92 | 33 |
| 3Q GAIN MUTATED | 16 | 5 | 24 | 4 | 7 | 0 |
| 3Q GAIN WILD-TYPE | 72 | 81 | 66 | 78 | 85 | 33 |
Figure S28. Get High-res Image Gene #6: '3q gain' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 2e-05 (Fisher's exact test), Q value = 0.00012
Table S29. Gene #6: '3q gain' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 135 | 112 | 85 | 139 |
| 3Q GAIN MUTATED | 8 | 14 | 25 | 9 |
| 3Q GAIN WILD-TYPE | 127 | 98 | 60 | 130 |
Figure S29. Get High-res Image Gene #6: '3q gain' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
P value = 6e-05 (Fisher's exact test), Q value = 0.00032
Table S30. Gene #6: '3q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 111 | 221 | 193 |
| 3Q GAIN MUTATED | 12 | 11 | 38 |
| 3Q GAIN WILD-TYPE | 99 | 210 | 155 |
Figure S30. Get High-res Image Gene #6: '3q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 2e-05 (Fisher's exact test), Q value = 0.00012
Table S31. Gene #6: '3q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 117 | 33 | 183 | 132 | 35 | 25 |
| 3Q GAIN MUTATED | 8 | 4 | 8 | 30 | 7 | 4 |
| 3Q GAIN WILD-TYPE | 109 | 29 | 175 | 102 | 28 | 21 |
Figure S31. Get High-res Image Gene #6: '3q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 6.5e-05
Table S32. Gene #6: '3q gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 124 | 204 | 182 |
| 3Q GAIN MUTATED | 8 | 10 | 42 |
| 3Q GAIN WILD-TYPE | 116 | 194 | 140 |
Figure S32. Get High-res Image Gene #6: '3q gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 4e-04 (Fisher's exact test), Q value = 0.0017
Table S33. Gene #6: '3q gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 144 | 134 | 195 | 37 |
| 3Q GAIN MUTATED | 23 | 23 | 9 | 5 |
| 3Q GAIN WILD-TYPE | 121 | 111 | 186 | 32 |
Figure S33. Get High-res Image Gene #6: '3q gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00154 (Fisher's exact test), Q value = 0.0056
Table S34. Gene #6: '3q gain' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 38 | 21 | 48 | 35 |
| 3Q GAIN MUTATED | 3 | 0 | 2 | 10 |
| 3Q GAIN WILD-TYPE | 35 | 21 | 46 | 25 |
Figure S34. Get High-res Image Gene #6: '3q gain' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 0.0373 (Fisher's exact test), Q value = 0.085
Table S35. Gene #7: '4p gain' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 88 | 86 | 90 | 82 | 92 | 33 |
| 4P GAIN MUTATED | 3 | 1 | 5 | 0 | 0 | 0 |
| 4P GAIN WILD-TYPE | 85 | 85 | 85 | 82 | 92 | 33 |
Figure S35. Get High-res Image Gene #7: '4p gain' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 5e-05 (Fisher's exact test), Q value = 0.00027
Table S36. Gene #7: '4p gain' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 135 | 112 | 85 | 139 |
| 4P GAIN MUTATED | 0 | 2 | 7 | 0 |
| 4P GAIN WILD-TYPE | 135 | 110 | 78 | 139 |
Figure S36. Get High-res Image Gene #7: '4p gain' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
P value = 0.00038 (Fisher's exact test), Q value = 0.0017
Table S37. Gene #7: '4p gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 111 | 221 | 193 |
| 4P GAIN MUTATED | 7 | 0 | 5 |
| 4P GAIN WILD-TYPE | 104 | 221 | 188 |
Figure S37. Get High-res Image Gene #7: '4p gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 0.00041 (Fisher's exact test), Q value = 0.0018
Table S38. Gene #7: '4p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 117 | 33 | 183 | 132 | 35 | 25 |
| 4P GAIN MUTATED | 3 | 0 | 0 | 5 | 0 | 4 |
| 4P GAIN WILD-TYPE | 114 | 33 | 183 | 127 | 35 | 21 |
Figure S38. Get High-res Image Gene #7: '4p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00023 (Fisher's exact test), Q value = 0.0011
Table S39. Gene #7: '4p gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 124 | 204 | 182 |
| 4P GAIN MUTATED | 2 | 0 | 11 |
| 4P GAIN WILD-TYPE | 122 | 204 | 171 |
Figure S39. Get High-res Image Gene #7: '4p gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.0448 (Fisher's exact test), Q value = 0.098
Table S40. Gene #7: '4p gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 144 | 134 | 195 | 37 |
| 4P GAIN MUTATED | 4 | 7 | 1 | 1 |
| 4P GAIN WILD-TYPE | 140 | 127 | 194 | 36 |
Figure S40. Get High-res Image Gene #7: '4p gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0015 (Fisher's exact test), Q value = 0.0055
Table S41. Gene #8: '4q gain' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 135 | 112 | 85 | 139 |
| 4Q GAIN MUTATED | 1 | 2 | 6 | 0 |
| 4Q GAIN WILD-TYPE | 134 | 110 | 79 | 139 |
Figure S41. Get High-res Image Gene #8: '4q gain' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
P value = 0.00032 (Fisher's exact test), Q value = 0.0015
Table S42. Gene #8: '4q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 111 | 221 | 193 |
| 4Q GAIN MUTATED | 7 | 0 | 5 |
| 4Q GAIN WILD-TYPE | 104 | 221 | 188 |
Figure S42. Get High-res Image Gene #8: '4q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 0.00435 (Fisher's exact test), Q value = 0.014
Table S43. Gene #8: '4q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 117 | 33 | 183 | 132 | 35 | 25 |
| 4Q GAIN MUTATED | 3 | 0 | 1 | 4 | 0 | 4 |
| 4Q GAIN WILD-TYPE | 114 | 33 | 182 | 128 | 35 | 21 |
Figure S43. Get High-res Image Gene #8: '4q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00021 (Fisher's exact test), Q value = 0.001
Table S44. Gene #8: '4q gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 124 | 204 | 182 |
| 4Q GAIN MUTATED | 2 | 0 | 11 |
| 4Q GAIN WILD-TYPE | 122 | 204 | 171 |
Figure S44. Get High-res Image Gene #8: '4q gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.0442 (Fisher's exact test), Q value = 0.097
Table S45. Gene #8: '4q gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 144 | 134 | 195 | 37 |
| 4Q GAIN MUTATED | 4 | 7 | 1 | 1 |
| 4Q GAIN WILD-TYPE | 140 | 127 | 194 | 36 |
Figure S45. Get High-res Image Gene #8: '4q gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00036 (Fisher's exact test), Q value = 0.0016
Table S46. Gene #9: '5p gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 238 | 135 | 155 |
| 5P GAIN MUTATED | 73 | 43 | 77 |
| 5P GAIN WILD-TYPE | 165 | 92 | 78 |
Figure S46. Get High-res Image Gene #9: '5p gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.0186 (Fisher's exact test), Q value = 0.048
Table S47. Gene #9: '5p gain' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 88 | 86 | 90 | 82 | 92 | 33 |
| 5P GAIN MUTATED | 31 | 20 | 40 | 37 | 37 | 9 |
| 5P GAIN WILD-TYPE | 57 | 66 | 50 | 45 | 55 | 24 |
Figure S47. Get High-res Image Gene #9: '5p gain' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 0.00864 (Fisher's exact test), Q value = 0.026
Table S48. Gene #9: '5p gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 111 | 221 | 193 |
| 5P GAIN MUTATED | 29 | 78 | 84 |
| 5P GAIN WILD-TYPE | 82 | 143 | 109 |
Figure S48. Get High-res Image Gene #9: '5p gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 0.0217 (Fisher's exact test), Q value = 0.055
Table S49. Gene #9: '5p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 117 | 33 | 183 | 132 | 35 | 25 |
| 5P GAIN MUTATED | 44 | 8 | 60 | 60 | 15 | 4 |
| 5P GAIN WILD-TYPE | 73 | 25 | 123 | 72 | 20 | 21 |
Figure S49. Get High-res Image Gene #9: '5p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0225 (Fisher's exact test), Q value = 0.057
Table S50. Gene #10: '5q gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 238 | 135 | 155 |
| 5Q GAIN MUTATED | 85 | 47 | 75 |
| 5Q GAIN WILD-TYPE | 153 | 88 | 80 |
Figure S50. Get High-res Image Gene #10: '5q gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.00708 (Fisher's exact test), Q value = 0.022
Table S51. Gene #10: '5q gain' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 88 | 86 | 90 | 82 | 92 | 33 |
| 5Q GAIN MUTATED | 35 | 20 | 38 | 41 | 42 | 11 |
| 5Q GAIN WILD-TYPE | 53 | 66 | 52 | 41 | 50 | 22 |
Figure S51. Get High-res Image Gene #10: '5q gain' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 6.5e-05
Table S52. Gene #13: '7p gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 238 | 135 | 155 |
| 7P GAIN MUTATED | 39 | 46 | 86 |
| 7P GAIN WILD-TYPE | 199 | 89 | 69 |
Figure S52. Get High-res Image Gene #13: '7p gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.00147 (Fisher's exact test), Q value = 0.0054
Table S53. Gene #13: '7p gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 128 | 76 | 110 |
| 7P GAIN MUTATED | 26 | 16 | 44 |
| 7P GAIN WILD-TYPE | 102 | 60 | 66 |
Figure S53. Get High-res Image Gene #13: '7p gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 6.5e-05
Table S54. Gene #13: '7p gain' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 88 | 86 | 90 | 82 | 92 | 33 |
| 7P GAIN MUTATED | 32 | 21 | 50 | 23 | 22 | 5 |
| 7P GAIN WILD-TYPE | 56 | 65 | 40 | 59 | 70 | 28 |
Figure S54. Get High-res Image Gene #13: '7p gain' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 4e-05 (Fisher's exact test), Q value = 0.00022
Table S55. Gene #13: '7p gain' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 135 | 112 | 85 | 139 |
| 7P GAIN MUTATED | 34 | 48 | 41 | 30 |
| 7P GAIN WILD-TYPE | 101 | 64 | 44 | 109 |
Figure S55. Get High-res Image Gene #13: '7p gain' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
P value = 5e-05 (Fisher's exact test), Q value = 0.00027
Table S56. Gene #13: '7p gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 111 | 221 | 193 |
| 7P GAIN MUTATED | 31 | 53 | 85 |
| 7P GAIN WILD-TYPE | 80 | 168 | 108 |
Figure S56. Get High-res Image Gene #13: '7p gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 0.00953 (Fisher's exact test), Q value = 0.028
Table S57. Gene #13: '7p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 117 | 33 | 183 | 132 | 35 | 25 |
| 7P GAIN MUTATED | 38 | 9 | 45 | 59 | 12 | 6 |
| 7P GAIN WILD-TYPE | 79 | 24 | 138 | 73 | 23 | 19 |
Figure S57. Get High-res Image Gene #13: '7p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00411 (Fisher's exact test), Q value = 0.014
Table S58. Gene #13: '7p gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 124 | 204 | 182 |
| 7P GAIN MUTATED | 34 | 57 | 77 |
| 7P GAIN WILD-TYPE | 90 | 147 | 105 |
Figure S58. Get High-res Image Gene #13: '7p gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.031 (Fisher's exact test), Q value = 0.074
Table S59. Gene #13: '7p gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 144 | 134 | 195 | 37 |
| 7P GAIN MUTATED | 42 | 54 | 55 | 17 |
| 7P GAIN WILD-TYPE | 102 | 80 | 140 | 20 |
Figure S59. Get High-res Image Gene #13: '7p gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 6.5e-05
Table S60. Gene #14: '7q gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 238 | 135 | 155 |
| 7Q GAIN MUTATED | 39 | 47 | 86 |
| 7Q GAIN WILD-TYPE | 199 | 88 | 69 |
Figure S60. Get High-res Image Gene #14: '7q gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.00405 (Fisher's exact test), Q value = 0.013
Table S61. Gene #14: '7q gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 128 | 76 | 110 |
| 7Q GAIN MUTATED | 28 | 17 | 44 |
| 7Q GAIN WILD-TYPE | 100 | 59 | 66 |
Figure S61. Get High-res Image Gene #14: '7q gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 3e-05 (Fisher's exact test), Q value = 0.00017
Table S62. Gene #14: '7q gain' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 88 | 86 | 90 | 82 | 92 | 33 |
| 7Q GAIN MUTATED | 32 | 21 | 50 | 24 | 23 | 4 |
| 7Q GAIN WILD-TYPE | 56 | 65 | 40 | 58 | 69 | 29 |
Figure S62. Get High-res Image Gene #14: '7q gain' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 2e-05 (Fisher's exact test), Q value = 0.00012
Table S63. Gene #14: '7q gain' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 135 | 112 | 85 | 139 |
| 7Q GAIN MUTATED | 35 | 49 | 41 | 29 |
| 7Q GAIN WILD-TYPE | 100 | 63 | 44 | 110 |
Figure S63. Get High-res Image Gene #14: '7q gain' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
P value = 8e-05 (Fisher's exact test), Q value = 0.00041
Table S64. Gene #14: '7q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 111 | 221 | 193 |
| 7Q GAIN MUTATED | 32 | 53 | 85 |
| 7Q GAIN WILD-TYPE | 79 | 168 | 108 |
Figure S64. Get High-res Image Gene #14: '7q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 0.007 (Fisher's exact test), Q value = 0.021
Table S65. Gene #14: '7q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 117 | 33 | 183 | 132 | 35 | 25 |
| 7Q GAIN MUTATED | 37 | 11 | 44 | 59 | 13 | 6 |
| 7Q GAIN WILD-TYPE | 80 | 22 | 139 | 73 | 22 | 19 |
Figure S65. Get High-res Image Gene #14: '7q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00516 (Fisher's exact test), Q value = 0.016
Table S66. Gene #14: '7q gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 124 | 204 | 182 |
| 7Q GAIN MUTATED | 34 | 58 | 77 |
| 7Q GAIN WILD-TYPE | 90 | 146 | 105 |
Figure S66. Get High-res Image Gene #14: '7q gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.0178 (Fisher's exact test), Q value = 0.047
Table S67. Gene #14: '7q gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 144 | 134 | 195 | 37 |
| 7Q GAIN MUTATED | 44 | 55 | 53 | 17 |
| 7Q GAIN WILD-TYPE | 100 | 79 | 142 | 20 |
Figure S67. Get High-res Image Gene #14: '7q gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 6.5e-05
Table S68. Gene #15: '8p gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 238 | 135 | 155 |
| 8P GAIN MUTATED | 1 | 8 | 22 |
| 8P GAIN WILD-TYPE | 237 | 127 | 133 |
Figure S68. Get High-res Image Gene #15: '8p gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.00042 (Fisher's exact test), Q value = 0.0018
Table S69. Gene #15: '8p gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 128 | 76 | 110 |
| 8P GAIN MUTATED | 2 | 4 | 16 |
| 8P GAIN WILD-TYPE | 126 | 72 | 94 |
Figure S69. Get High-res Image Gene #15: '8p gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.00044 (Fisher's exact test), Q value = 0.0019
Table S70. Gene #15: '8p gain' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 88 | 86 | 90 | 82 | 92 | 33 |
| 8P GAIN MUTATED | 3 | 2 | 16 | 4 | 4 | 0 |
| 8P GAIN WILD-TYPE | 85 | 84 | 74 | 78 | 88 | 33 |
Figure S70. Get High-res Image Gene #15: '8p gain' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 6.5e-05
Table S71. Gene #15: '8p gain' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 135 | 112 | 85 | 139 |
| 8P GAIN MUTATED | 1 | 18 | 7 | 3 |
| 8P GAIN WILD-TYPE | 134 | 94 | 78 | 136 |
Figure S71. Get High-res Image Gene #15: '8p gain' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 6.5e-05
Table S72. Gene #15: '8p gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 111 | 221 | 193 |
| 8P GAIN MUTATED | 4 | 3 | 24 |
| 8P GAIN WILD-TYPE | 107 | 218 | 169 |
Figure S72. Get High-res Image Gene #15: '8p gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 2e-05 (Fisher's exact test), Q value = 0.00012
Table S73. Gene #15: '8p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 117 | 33 | 183 | 132 | 35 | 25 |
| 8P GAIN MUTATED | 6 | 2 | 1 | 19 | 2 | 1 |
| 8P GAIN WILD-TYPE | 111 | 31 | 182 | 113 | 33 | 24 |
Figure S73. Get High-res Image Gene #15: '8p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 6.5e-05
Table S74. Gene #15: '8p gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 124 | 204 | 182 |
| 8P GAIN MUTATED | 3 | 3 | 25 |
| 8P GAIN WILD-TYPE | 121 | 201 | 157 |
Figure S74. Get High-res Image Gene #15: '8p gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.00477 (Fisher's exact test), Q value = 0.015
Table S75. Gene #15: '8p gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 144 | 134 | 195 | 37 |
| 8P GAIN MUTATED | 10 | 12 | 4 | 5 |
| 8P GAIN WILD-TYPE | 134 | 122 | 191 | 32 |
Figure S75. Get High-res Image Gene #15: '8p gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0116 (Fisher's exact test), Q value = 0.033
Table S76. Gene #15: '8p gain' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 38 | 21 | 48 | 35 |
| 8P GAIN MUTATED | 1 | 0 | 0 | 5 |
| 8P GAIN WILD-TYPE | 37 | 21 | 48 | 30 |
Figure S76. Get High-res Image Gene #15: '8p gain' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 6.5e-05
Table S77. Gene #16: '8q gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 238 | 135 | 155 |
| 8Q GAIN MUTATED | 3 | 13 | 46 |
| 8Q GAIN WILD-TYPE | 235 | 122 | 109 |
Figure S77. Get High-res Image Gene #16: '8q gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 6.5e-05
Table S78. Gene #16: '8q gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 128 | 76 | 110 |
| 8Q GAIN MUTATED | 3 | 11 | 26 |
| 8Q GAIN WILD-TYPE | 125 | 65 | 84 |
Figure S78. Get High-res Image Gene #16: '8q gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 6.5e-05
Table S79. Gene #16: '8q gain' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 88 | 86 | 90 | 82 | 92 | 33 |
| 8Q GAIN MUTATED | 10 | 3 | 30 | 6 | 8 | 1 |
| 8Q GAIN WILD-TYPE | 78 | 83 | 60 | 76 | 84 | 32 |
Figure S79. Get High-res Image Gene #16: '8q gain' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 6.5e-05
Table S80. Gene #16: '8q gain' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 135 | 112 | 85 | 139 |
| 8Q GAIN MUTATED | 5 | 29 | 17 | 7 |
| 8Q GAIN WILD-TYPE | 130 | 83 | 68 | 132 |
Figure S80. Get High-res Image Gene #16: '8q gain' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 6.5e-05
Table S81. Gene #16: '8q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 111 | 221 | 193 |
| 8Q GAIN MUTATED | 5 | 6 | 50 |
| 8Q GAIN WILD-TYPE | 106 | 215 | 143 |
Figure S81. Get High-res Image Gene #16: '8q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 6.5e-05
Table S82. Gene #16: '8q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 117 | 33 | 183 | 132 | 35 | 25 |
| 8Q GAIN MUTATED | 8 | 2 | 4 | 42 | 4 | 1 |
| 8Q GAIN WILD-TYPE | 109 | 31 | 179 | 90 | 31 | 24 |
Figure S82. Get High-res Image Gene #16: '8q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 6.5e-05
Table S83. Gene #16: '8q gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 124 | 204 | 182 |
| 8Q GAIN MUTATED | 8 | 7 | 45 |
| 8Q GAIN WILD-TYPE | 116 | 197 | 137 |
Figure S83. Get High-res Image Gene #16: '8q gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.00014 (Fisher's exact test), Q value = 0.00069
Table S84. Gene #16: '8q gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 144 | 134 | 195 | 37 |
| 8Q GAIN MUTATED | 20 | 22 | 9 | 9 |
| 8Q GAIN WILD-TYPE | 124 | 112 | 186 | 28 |
Figure S84. Get High-res Image Gene #16: '8q gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00047 (Fisher's exact test), Q value = 0.002
Table S85. Gene #16: '8q gain' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 38 | 21 | 48 | 35 |
| 8Q GAIN MUTATED | 3 | 0 | 1 | 10 |
| 8Q GAIN WILD-TYPE | 35 | 21 | 47 | 25 |
Figure S85. Get High-res Image Gene #16: '8q gain' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 0.0152 (Fisher's exact test), Q value = 0.041
Table S86. Gene #17: '9p gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 238 | 135 | 155 |
| 9P GAIN MUTATED | 4 | 8 | 1 |
| 9P GAIN WILD-TYPE | 234 | 127 | 154 |
Figure S86. Get High-res Image Gene #17: '9p gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.0342 (Fisher's exact test), Q value = 0.079
Table S87. Gene #17: '9p gain' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 135 | 112 | 85 | 139 |
| 9P GAIN MUTATED | 1 | 0 | 3 | 6 |
| 9P GAIN WILD-TYPE | 134 | 112 | 82 | 133 |
Figure S87. Get High-res Image Gene #17: '9p gain' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
P value = 0.0176 (Fisher's exact test), Q value = 0.046
Table S88. Gene #17: '9p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 117 | 33 | 183 | 132 | 35 | 25 |
| 9P GAIN MUTATED | 0 | 0 | 7 | 2 | 1 | 3 |
| 9P GAIN WILD-TYPE | 117 | 33 | 176 | 130 | 34 | 22 |
Figure S88. Get High-res Image Gene #17: '9p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00139 (Fisher's exact test), Q value = 0.0052
Table S89. Gene #18: '9q gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 238 | 135 | 155 |
| 9Q GAIN MUTATED | 2 | 9 | 1 |
| 9Q GAIN WILD-TYPE | 236 | 126 | 154 |
Figure S89. Get High-res Image Gene #18: '9q gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.0316 (Fisher's exact test), Q value = 0.075
Table S90. Gene #18: '9q gain' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 135 | 112 | 85 | 139 |
| 9Q GAIN MUTATED | 0 | 1 | 4 | 4 |
| 9Q GAIN WILD-TYPE | 135 | 111 | 81 | 135 |
Figure S90. Get High-res Image Gene #18: '9q gain' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
P value = 0.0262 (Fisher's exact test), Q value = 0.064
Table S91. Gene #18: '9q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 117 | 33 | 183 | 132 | 35 | 25 |
| 9Q GAIN MUTATED | 0 | 0 | 4 | 4 | 1 | 3 |
| 9Q GAIN WILD-TYPE | 117 | 33 | 179 | 128 | 34 | 22 |
Figure S91. Get High-res Image Gene #18: '9q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00024 (Fisher's exact test), Q value = 0.0011
Table S92. Gene #19: '10p gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 238 | 135 | 155 |
| 10P GAIN MUTATED | 1 | 4 | 12 |
| 10P GAIN WILD-TYPE | 237 | 131 | 143 |
Figure S92. Get High-res Image Gene #19: '10p gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.0239 (Fisher's exact test), Q value = 0.059
Table S93. Gene #19: '10p gain' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 88 | 86 | 90 | 82 | 92 | 33 |
| 10P GAIN MUTATED | 1 | 1 | 9 | 2 | 2 | 1 |
| 10P GAIN WILD-TYPE | 87 | 85 | 81 | 80 | 90 | 32 |
Figure S93. Get High-res Image Gene #19: '10p gain' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 0.00091 (Fisher's exact test), Q value = 0.0035
Table S94. Gene #19: '10p gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 111 | 221 | 193 |
| 10P GAIN MUTATED | 3 | 1 | 13 |
| 10P GAIN WILD-TYPE | 108 | 220 | 180 |
Figure S94. Get High-res Image Gene #19: '10p gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 0.00017 (Fisher's exact test), Q value = 0.00083
Table S95. Gene #19: '10p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 117 | 33 | 183 | 132 | 35 | 25 |
| 10P GAIN MUTATED | 2 | 1 | 0 | 12 | 2 | 0 |
| 10P GAIN WILD-TYPE | 115 | 32 | 183 | 120 | 33 | 25 |
Figure S95. Get High-res Image Gene #19: '10p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0186 (Fisher's exact test), Q value = 0.048
Table S96. Gene #19: '10p gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 124 | 204 | 182 |
| 10P GAIN MUTATED | 4 | 2 | 11 |
| 10P GAIN WILD-TYPE | 120 | 202 | 171 |
Figure S96. Get High-res Image Gene #19: '10p gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.00012 (Fisher's exact test), Q value = 6e-04
Table S97. Gene #20: '10q gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 238 | 135 | 155 |
| 10Q GAIN MUTATED | 0 | 3 | 9 |
| 10Q GAIN WILD-TYPE | 238 | 132 | 146 |
Figure S97. Get High-res Image Gene #20: '10q gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.014 (Fisher's exact test), Q value = 0.039
Table S98. Gene #20: '10q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 111 | 221 | 193 |
| 10Q GAIN MUTATED | 2 | 1 | 9 |
| 10Q GAIN WILD-TYPE | 109 | 220 | 184 |
Figure S98. Get High-res Image Gene #20: '10q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 0.00182 (Fisher's exact test), Q value = 0.0065
Table S99. Gene #20: '10q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 117 | 33 | 183 | 132 | 35 | 25 |
| 10Q GAIN MUTATED | 1 | 1 | 0 | 9 | 1 | 0 |
| 10Q GAIN WILD-TYPE | 116 | 32 | 183 | 123 | 34 | 25 |
Figure S99. Get High-res Image Gene #20: '10q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0154 (Fisher's exact test), Q value = 0.042
Table S100. Gene #20: '10q gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 124 | 204 | 182 |
| 10Q GAIN MUTATED | 2 | 1 | 9 |
| 10Q GAIN WILD-TYPE | 122 | 203 | 173 |
Figure S100. Get High-res Image Gene #20: '10q gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 6.5e-05
Table S101. Gene #21: '11p gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 238 | 135 | 155 |
| 11P GAIN MUTATED | 2 | 12 | 17 |
| 11P GAIN WILD-TYPE | 236 | 123 | 138 |
Figure S101. Get High-res Image Gene #21: '11p gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.00023 (Fisher's exact test), Q value = 0.0011
Table S102. Gene #22: '11q gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 238 | 135 | 155 |
| 11Q GAIN MUTATED | 3 | 12 | 14 |
| 11Q GAIN WILD-TYPE | 235 | 123 | 141 |
Figure S102. Get High-res Image Gene #22: '11q gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.0131 (Fisher's exact test), Q value = 0.036
Table S103. Gene #23: '12p gain' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 33 | 24 | 13 |
| 12P GAIN MUTATED | 3 | 10 | 2 |
| 12P GAIN WILD-TYPE | 30 | 14 | 11 |
Figure S103. Get High-res Image Gene #23: '12p gain' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 0.0326 (Fisher's exact test), Q value = 0.077
Table S104. Gene #23: '12p gain' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 11 | 12 | 4 | 11 | 13 | 9 | 10 |
| 12P GAIN MUTATED | 0 | 4 | 0 | 6 | 1 | 2 | 2 |
| 12P GAIN WILD-TYPE | 11 | 8 | 4 | 5 | 12 | 7 | 8 |
Figure S104. Get High-res Image Gene #23: '12p gain' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 6.5e-05
Table S105. Gene #23: '12p gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 238 | 135 | 155 |
| 12P GAIN MUTATED | 22 | 34 | 65 |
| 12P GAIN WILD-TYPE | 216 | 101 | 90 |
Figure S105. Get High-res Image Gene #23: '12p gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 6.5e-05
Table S106. Gene #23: '12p gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 128 | 76 | 110 |
| 12P GAIN MUTATED | 16 | 18 | 42 |
| 12P GAIN WILD-TYPE | 112 | 58 | 68 |
Figure S106. Get High-res Image Gene #23: '12p gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 6.5e-05
Table S107. Gene #23: '12p gain' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 88 | 86 | 90 | 82 | 92 | 33 |
| 12P GAIN MUTATED | 16 | 3 | 47 | 20 | 19 | 2 |
| 12P GAIN WILD-TYPE | 72 | 83 | 43 | 62 | 73 | 31 |
Figure S107. Get High-res Image Gene #23: '12p gain' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 2e-05 (Fisher's exact test), Q value = 0.00012
Table S108. Gene #23: '12p gain' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 135 | 112 | 85 | 139 |
| 12P GAIN MUTATED | 21 | 37 | 31 | 18 |
| 12P GAIN WILD-TYPE | 114 | 75 | 54 | 121 |
Figure S108. Get High-res Image Gene #23: '12p gain' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 6.5e-05
Table S109. Gene #23: '12p gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 111 | 221 | 193 |
| 12P GAIN MUTATED | 18 | 24 | 78 |
| 12P GAIN WILD-TYPE | 93 | 197 | 115 |
Figure S109. Get High-res Image Gene #23: '12p gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 6.5e-05
Table S110. Gene #23: '12p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 117 | 33 | 183 | 132 | 35 | 25 |
| 12P GAIN MUTATED | 22 | 5 | 19 | 58 | 11 | 5 |
| 12P GAIN WILD-TYPE | 95 | 28 | 164 | 74 | 24 | 20 |
Figure S110. Get High-res Image Gene #23: '12p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 6.5e-05
Table S111. Gene #23: '12p gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 124 | 204 | 182 |
| 12P GAIN MUTATED | 20 | 24 | 75 |
| 12P GAIN WILD-TYPE | 104 | 180 | 107 |
Figure S111. Get High-res Image Gene #23: '12p gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 6.5e-05
Table S112. Gene #23: '12p gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 144 | 134 | 195 | 37 |
| 12P GAIN MUTATED | 33 | 46 | 24 | 16 |
| 12P GAIN WILD-TYPE | 111 | 88 | 171 | 21 |
Figure S112. Get High-res Image Gene #23: '12p gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00149 (Fisher's exact test), Q value = 0.0055
Table S113. Gene #23: '12p gain' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 38 | 21 | 48 | 35 |
| 12P GAIN MUTATED | 4 | 4 | 5 | 15 |
| 12P GAIN WILD-TYPE | 34 | 17 | 43 | 20 |
Figure S113. Get High-res Image Gene #23: '12p gain' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 0.0132 (Fisher's exact test), Q value = 0.037
Table S114. Gene #24: '12q gain' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 33 | 24 | 13 |
| 12Q GAIN MUTATED | 3 | 10 | 2 |
| 12Q GAIN WILD-TYPE | 30 | 14 | 11 |
Figure S114. Get High-res Image Gene #24: '12q gain' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 0.0333 (Fisher's exact test), Q value = 0.078
Table S115. Gene #24: '12q gain' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 11 | 12 | 4 | 11 | 13 | 9 | 10 |
| 12Q GAIN MUTATED | 0 | 4 | 0 | 6 | 1 | 2 | 2 |
| 12Q GAIN WILD-TYPE | 11 | 8 | 4 | 5 | 12 | 7 | 8 |
Figure S115. Get High-res Image Gene #24: '12q gain' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 6.5e-05
Table S116. Gene #24: '12q gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 238 | 135 | 155 |
| 12Q GAIN MUTATED | 22 | 34 | 66 |
| 12Q GAIN WILD-TYPE | 216 | 101 | 89 |
Figure S116. Get High-res Image Gene #24: '12q gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 8e-05 (Fisher's exact test), Q value = 0.00041
Table S117. Gene #24: '12q gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 128 | 76 | 110 |
| 12Q GAIN MUTATED | 16 | 18 | 42 |
| 12Q GAIN WILD-TYPE | 112 | 58 | 68 |
Figure S117. Get High-res Image Gene #24: '12q gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 6.5e-05
Table S118. Gene #24: '12q gain' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 88 | 86 | 90 | 82 | 92 | 33 |
| 12Q GAIN MUTATED | 16 | 3 | 49 | 20 | 18 | 2 |
| 12Q GAIN WILD-TYPE | 72 | 83 | 41 | 62 | 74 | 31 |
Figure S118. Get High-res Image Gene #24: '12q gain' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 6.5e-05
Table S119. Gene #24: '12q gain' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 135 | 112 | 85 | 139 |
| 12Q GAIN MUTATED | 21 | 38 | 31 | 18 |
| 12Q GAIN WILD-TYPE | 114 | 74 | 54 | 121 |
Figure S119. Get High-res Image Gene #24: '12q gain' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 6.5e-05
Table S120. Gene #24: '12q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 111 | 221 | 193 |
| 12Q GAIN MUTATED | 19 | 24 | 78 |
| 12Q GAIN WILD-TYPE | 92 | 197 | 115 |
Figure S120. Get High-res Image Gene #24: '12q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 6.5e-05
Table S121. Gene #24: '12q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 117 | 33 | 183 | 132 | 35 | 25 |
| 12Q GAIN MUTATED | 22 | 5 | 19 | 59 | 11 | 5 |
| 12Q GAIN WILD-TYPE | 95 | 28 | 164 | 73 | 24 | 20 |
Figure S121. Get High-res Image Gene #24: '12q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 6.5e-05
Table S122. Gene #24: '12q gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 124 | 204 | 182 |
| 12Q GAIN MUTATED | 19 | 24 | 77 |
| 12Q GAIN WILD-TYPE | 105 | 180 | 105 |
Figure S122. Get High-res Image Gene #24: '12q gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 6.5e-05
Table S123. Gene #24: '12q gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 144 | 134 | 195 | 37 |
| 12Q GAIN MUTATED | 32 | 48 | 24 | 16 |
| 12Q GAIN WILD-TYPE | 112 | 86 | 171 | 21 |
Figure S123. Get High-res Image Gene #24: '12q gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00288 (Fisher's exact test), Q value = 0.01
Table S124. Gene #24: '12q gain' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 38 | 21 | 48 | 35 |
| 12Q GAIN MUTATED | 5 | 4 | 5 | 15 |
| 12Q GAIN WILD-TYPE | 33 | 17 | 43 | 20 |
Figure S124. Get High-res Image Gene #24: '12q gain' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 0.0344 (Fisher's exact test), Q value = 0.08
Table S125. Gene #25: '13q gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 128 | 76 | 110 |
| 13Q GAIN MUTATED | 6 | 1 | 11 |
| 13Q GAIN WILD-TYPE | 122 | 75 | 99 |
Figure S125. Get High-res Image Gene #25: '13q gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.00119 (Fisher's exact test), Q value = 0.0046
Table S126. Gene #26: '14q gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 238 | 135 | 155 |
| 14Q GAIN MUTATED | 1 | 8 | 7 |
| 14Q GAIN WILD-TYPE | 237 | 127 | 148 |
Figure S126. Get High-res Image Gene #26: '14q gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.00191 (Fisher's exact test), Q value = 0.0068
Table S127. Gene #26: '14q gain' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 88 | 86 | 90 | 82 | 92 | 33 |
| 14Q GAIN MUTATED | 5 | 0 | 7 | 1 | 0 | 0 |
| 14Q GAIN WILD-TYPE | 83 | 86 | 83 | 81 | 92 | 33 |
Figure S127. Get High-res Image Gene #26: '14q gain' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 0.0334 (Fisher's exact test), Q value = 0.078
Table S128. Gene #26: '14q gain' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 135 | 112 | 85 | 139 |
| 14Q GAIN MUTATED | 1 | 4 | 6 | 2 |
| 14Q GAIN WILD-TYPE | 134 | 108 | 79 | 137 |
Figure S128. Get High-res Image Gene #26: '14q gain' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
P value = 0.00694 (Fisher's exact test), Q value = 0.021
Table S129. Gene #26: '14q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 111 | 221 | 193 |
| 14Q GAIN MUTATED | 8 | 2 | 6 |
| 14Q GAIN WILD-TYPE | 103 | 219 | 187 |
Figure S129. Get High-res Image Gene #26: '14q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 0.00034 (Fisher's exact test), Q value = 0.0015
Table S130. Gene #26: '14q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 117 | 33 | 183 | 132 | 35 | 25 |
| 14Q GAIN MUTATED | 3 | 0 | 1 | 7 | 0 | 5 |
| 14Q GAIN WILD-TYPE | 114 | 33 | 182 | 125 | 35 | 20 |
Figure S130. Get High-res Image Gene #26: '14q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00403 (Fisher's exact test), Q value = 0.013
Table S131. Gene #26: '14q gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 124 | 204 | 182 |
| 14Q GAIN MUTATED | 3 | 1 | 11 |
| 14Q GAIN WILD-TYPE | 121 | 203 | 171 |
Figure S131. Get High-res Image Gene #26: '14q gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.00077 (Fisher's exact test), Q value = 0.0031
Table S132. Gene #27: '15q gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 238 | 135 | 155 |
| 15Q GAIN MUTATED | 3 | 11 | 12 |
| 15Q GAIN WILD-TYPE | 235 | 124 | 143 |
Figure S132. Get High-res Image Gene #27: '15q gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.00385 (Fisher's exact test), Q value = 0.013
Table S133. Gene #27: '15q gain' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 135 | 112 | 85 | 139 |
| 15Q GAIN MUTATED | 0 | 7 | 6 | 9 |
| 15Q GAIN WILD-TYPE | 135 | 105 | 79 | 130 |
Figure S133. Get High-res Image Gene #27: '15q gain' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
P value = 9e-05 (Fisher's exact test), Q value = 0.00046
Table S134. Gene #28: '16p gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 238 | 135 | 155 |
| 16P GAIN MUTATED | 30 | 29 | 48 |
| 16P GAIN WILD-TYPE | 208 | 106 | 107 |
Figure S134. Get High-res Image Gene #28: '16p gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.0215 (Fisher's exact test), Q value = 0.055
Table S135. Gene #28: '16p gain' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 88 | 86 | 90 | 82 | 92 | 33 |
| 16P GAIN MUTATED | 23 | 10 | 23 | 22 | 13 | 4 |
| 16P GAIN WILD-TYPE | 65 | 76 | 67 | 60 | 79 | 29 |
Figure S135. Get High-res Image Gene #28: '16p gain' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 0.00671 (Fisher's exact test), Q value = 0.021
Table S136. Gene #28: '16p gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 111 | 221 | 193 |
| 16P GAIN MUTATED | 23 | 32 | 52 |
| 16P GAIN WILD-TYPE | 88 | 189 | 141 |
Figure S136. Get High-res Image Gene #28: '16p gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 0.00438 (Fisher's exact test), Q value = 0.014
Table S137. Gene #28: '16p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 117 | 33 | 183 | 132 | 35 | 25 |
| 16P GAIN MUTATED | 26 | 13 | 23 | 34 | 6 | 5 |
| 16P GAIN WILD-TYPE | 91 | 20 | 160 | 98 | 29 | 20 |
Figure S137. Get High-res Image Gene #28: '16p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0259 (Fisher's exact test), Q value = 0.063
Table S138. Gene #28: '16p gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 144 | 134 | 195 | 37 |
| 16P GAIN MUTATED | 26 | 40 | 32 | 8 |
| 16P GAIN WILD-TYPE | 118 | 94 | 163 | 29 |
Figure S138. Get High-res Image Gene #28: '16p gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 4e-05 (Fisher's exact test), Q value = 0.00022
Table S139. Gene #29: '16q gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 238 | 135 | 155 |
| 16Q GAIN MUTATED | 26 | 29 | 44 |
| 16Q GAIN WILD-TYPE | 212 | 106 | 111 |
Figure S139. Get High-res Image Gene #29: '16q gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.00558 (Fisher's exact test), Q value = 0.018
Table S140. Gene #29: '16q gain' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 88 | 86 | 90 | 82 | 92 | 33 |
| 16Q GAIN MUTATED | 23 | 7 | 23 | 18 | 12 | 4 |
| 16Q GAIN WILD-TYPE | 65 | 79 | 67 | 64 | 80 | 29 |
Figure S140. Get High-res Image Gene #29: '16q gain' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 0.00626 (Fisher's exact test), Q value = 0.019
Table S141. Gene #29: '16q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 111 | 221 | 193 |
| 16Q GAIN MUTATED | 21 | 29 | 49 |
| 16Q GAIN WILD-TYPE | 90 | 192 | 144 |
Figure S141. Get High-res Image Gene #29: '16q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 0.016 (Fisher's exact test), Q value = 0.043
Table S142. Gene #29: '16q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 117 | 33 | 183 | 132 | 35 | 25 |
| 16Q GAIN MUTATED | 23 | 11 | 22 | 33 | 6 | 4 |
| 16Q GAIN WILD-TYPE | 94 | 22 | 161 | 99 | 29 | 21 |
Figure S142. Get High-res Image Gene #29: '16q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0162 (Fisher's exact test), Q value = 0.043
Table S143. Gene #29: '16q gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 124 | 204 | 182 |
| 16Q GAIN MUTATED | 24 | 28 | 46 |
| 16Q GAIN WILD-TYPE | 100 | 176 | 136 |
Figure S143. Get High-res Image Gene #29: '16q gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.0181 (Fisher's exact test), Q value = 0.047
Table S144. Gene #30: '17p gain' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 33 | 24 | 13 |
| 17P GAIN MUTATED | 1 | 0 | 3 |
| 17P GAIN WILD-TYPE | 32 | 24 | 10 |
Figure S144. Get High-res Image Gene #30: '17p gain' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 0.00532 (Fisher's exact test), Q value = 0.017
Table S145. Gene #30: '17p gain' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 11 | 12 | 4 | 11 | 13 | 9 | 10 |
| 17P GAIN MUTATED | 0 | 0 | 2 | 0 | 0 | 1 | 1 |
| 17P GAIN WILD-TYPE | 11 | 12 | 2 | 11 | 13 | 8 | 9 |
Figure S145. Get High-res Image Gene #30: '17p gain' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
P value = 2e-05 (Fisher's exact test), Q value = 0.00012
Table S146. Gene #30: '17p gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 238 | 135 | 155 |
| 17P GAIN MUTATED | 1 | 10 | 15 |
| 17P GAIN WILD-TYPE | 237 | 125 | 140 |
Figure S146. Get High-res Image Gene #30: '17p gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.00497 (Fisher's exact test), Q value = 0.016
Table S147. Gene #30: '17p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 117 | 33 | 183 | 132 | 35 | 25 |
| 17P GAIN MUTATED | 2 | 6 | 5 | 10 | 2 | 1 |
| 17P GAIN WILD-TYPE | 115 | 27 | 178 | 122 | 33 | 24 |
Figure S147. Get High-res Image Gene #30: '17p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0346 (Fisher's exact test), Q value = 0.08
Table S148. Gene #30: '17p gain' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 38 | 21 | 48 | 35 |
| 17P GAIN MUTATED | 1 | 0 | 0 | 4 |
| 17P GAIN WILD-TYPE | 37 | 21 | 48 | 31 |
Figure S148. Get High-res Image Gene #30: '17p gain' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 0.026 (Fisher's exact test), Q value = 0.063
Table S149. Gene #31: '17q gain' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 11 | 12 | 4 | 11 | 13 | 9 | 10 |
| 17Q GAIN MUTATED | 0 | 0 | 2 | 1 | 0 | 1 | 1 |
| 17Q GAIN WILD-TYPE | 11 | 12 | 2 | 10 | 13 | 8 | 9 |
Figure S149. Get High-res Image Gene #31: '17q gain' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 6.5e-05
Table S150. Gene #31: '17q gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 238 | 135 | 155 |
| 17Q GAIN MUTATED | 3 | 11 | 19 |
| 17Q GAIN WILD-TYPE | 235 | 124 | 136 |
Figure S150. Get High-res Image Gene #31: '17q gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.00167 (Fisher's exact test), Q value = 0.0061
Table S151. Gene #31: '17q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 117 | 33 | 183 | 132 | 35 | 25 |
| 17Q GAIN MUTATED | 3 | 7 | 6 | 13 | 3 | 1 |
| 17Q GAIN WILD-TYPE | 114 | 26 | 177 | 119 | 32 | 24 |
Figure S151. Get High-res Image Gene #31: '17q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0021 (Fisher's exact test), Q value = 0.0074
Table S152. Gene #31: '17q gain' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 38 | 21 | 48 | 35 |
| 17Q GAIN MUTATED | 1 | 0 | 0 | 6 |
| 17Q GAIN WILD-TYPE | 37 | 21 | 48 | 29 |
Figure S152. Get High-res Image Gene #31: '17q gain' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 0.0442 (Fisher's exact test), Q value = 0.097
Table S153. Gene #32: '18p gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 39 | 56 | 47 |
| 18P GAIN MUTATED | 1 | 1 | 6 |
| 18P GAIN WILD-TYPE | 38 | 55 | 41 |
Figure S153. Get High-res Image Gene #32: '18p gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.0441 (Fisher's exact test), Q value = 0.097
Table S154. Gene #33: '18q gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 39 | 56 | 47 |
| 18Q GAIN MUTATED | 1 | 1 | 6 |
| 18Q GAIN WILD-TYPE | 38 | 55 | 41 |
Figure S154. Get High-res Image Gene #33: '18q gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 6.5e-05
Table S155. Gene #34: '19p gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 238 | 135 | 155 |
| 19P GAIN MUTATED | 4 | 19 | 28 |
| 19P GAIN WILD-TYPE | 234 | 116 | 127 |
Figure S155. Get High-res Image Gene #34: '19p gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 5e-05 (Fisher's exact test), Q value = 0.00027
Table S156. Gene #34: '19p gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 128 | 76 | 110 |
| 19P GAIN MUTATED | 7 | 3 | 24 |
| 19P GAIN WILD-TYPE | 121 | 73 | 86 |
Figure S156. Get High-res Image Gene #34: '19p gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.00146 (Fisher's exact test), Q value = 0.0054
Table S157. Gene #34: '19p gain' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 88 | 86 | 90 | 82 | 92 | 33 |
| 19P GAIN MUTATED | 13 | 3 | 17 | 7 | 6 | 0 |
| 19P GAIN WILD-TYPE | 75 | 83 | 73 | 75 | 86 | 33 |
Figure S157. Get High-res Image Gene #34: '19p gain' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 0.0127 (Fisher's exact test), Q value = 0.036
Table S158. Gene #34: '19p gain' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 135 | 112 | 85 | 139 |
| 19P GAIN MUTATED | 6 | 17 | 12 | 11 |
| 19P GAIN WILD-TYPE | 129 | 95 | 73 | 128 |
Figure S158. Get High-res Image Gene #34: '19p gain' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
P value = 0.00163 (Fisher's exact test), Q value = 0.0059
Table S159. Gene #34: '19p gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 111 | 221 | 193 |
| 19P GAIN MUTATED | 14 | 10 | 27 |
| 19P GAIN WILD-TYPE | 97 | 211 | 166 |
Figure S159. Get High-res Image Gene #34: '19p gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 0.00078 (Fisher's exact test), Q value = 0.0031
Table S160. Gene #34: '19p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 117 | 33 | 183 | 132 | 35 | 25 |
| 19P GAIN MUTATED | 10 | 2 | 8 | 24 | 2 | 5 |
| 19P GAIN WILD-TYPE | 107 | 31 | 175 | 108 | 33 | 20 |
Figure S160. Get High-res Image Gene #34: '19p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 3e-05 (Fisher's exact test), Q value = 0.00017
Table S161. Gene #34: '19p gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 124 | 204 | 182 |
| 19P GAIN MUTATED | 10 | 8 | 32 |
| 19P GAIN WILD-TYPE | 114 | 196 | 150 |
Figure S161. Get High-res Image Gene #34: '19p gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 6.5e-05
Table S162. Gene #35: '19q gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 238 | 135 | 155 |
| 19Q GAIN MUTATED | 4 | 19 | 34 |
| 19Q GAIN WILD-TYPE | 234 | 116 | 121 |
Figure S162. Get High-res Image Gene #35: '19q gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 4e-05 (Fisher's exact test), Q value = 0.00022
Table S163. Gene #35: '19q gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 128 | 76 | 110 |
| 19Q GAIN MUTATED | 7 | 3 | 27 |
| 19Q GAIN WILD-TYPE | 121 | 73 | 83 |
Figure S163. Get High-res Image Gene #35: '19q gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 2e-05 (Fisher's exact test), Q value = 0.00012
Table S164. Gene #35: '19q gain' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 88 | 86 | 90 | 82 | 92 | 33 |
| 19Q GAIN MUTATED | 13 | 3 | 23 | 7 | 6 | 0 |
| 19Q GAIN WILD-TYPE | 75 | 83 | 67 | 75 | 86 | 33 |
Figure S164. Get High-res Image Gene #35: '19q gain' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 0.00064 (Fisher's exact test), Q value = 0.0026
Table S165. Gene #35: '19q gain' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 135 | 112 | 85 | 139 |
| 19Q GAIN MUTATED | 6 | 20 | 15 | 11 |
| 19Q GAIN WILD-TYPE | 129 | 92 | 70 | 128 |
Figure S165. Get High-res Image Gene #35: '19q gain' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
P value = 0.00059 (Fisher's exact test), Q value = 0.0024
Table S166. Gene #35: '19q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 111 | 221 | 193 |
| 19Q GAIN MUTATED | 14 | 11 | 31 |
| 19Q GAIN WILD-TYPE | 97 | 210 | 162 |
Figure S166. Get High-res Image Gene #35: '19q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 9e-05 (Fisher's exact test), Q value = 0.00046
Table S167. Gene #35: '19q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 117 | 33 | 183 | 132 | 35 | 25 |
| 19Q GAIN MUTATED | 11 | 2 | 8 | 28 | 2 | 5 |
| 19Q GAIN WILD-TYPE | 106 | 31 | 175 | 104 | 33 | 20 |
Figure S167. Get High-res Image Gene #35: '19q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 6.5e-05
Table S168. Gene #35: '19q gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 124 | 204 | 182 |
| 19Q GAIN MUTATED | 10 | 9 | 36 |
| 19Q GAIN WILD-TYPE | 114 | 195 | 146 |
Figure S168. Get High-res Image Gene #35: '19q gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 6.5e-05
Table S169. Gene #36: '20p gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 238 | 135 | 155 |
| 20P GAIN MUTATED | 10 | 39 | 63 |
| 20P GAIN WILD-TYPE | 228 | 96 | 92 |
Figure S169. Get High-res Image Gene #36: '20p gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 2e-05 (Fisher's exact test), Q value = 0.00012
Table S170. Gene #36: '20p gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 128 | 76 | 110 |
| 20P GAIN MUTATED | 12 | 16 | 37 |
| 20P GAIN WILD-TYPE | 116 | 60 | 73 |
Figure S170. Get High-res Image Gene #36: '20p gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 6.5e-05
Table S171. Gene #36: '20p gain' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 88 | 86 | 90 | 82 | 92 | 33 |
| 20P GAIN MUTATED | 19 | 5 | 45 | 11 | 19 | 2 |
| 20P GAIN WILD-TYPE | 69 | 81 | 45 | 71 | 73 | 31 |
Figure S171. Get High-res Image Gene #36: '20p gain' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 6.5e-05
Table S172. Gene #36: '20p gain' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 135 | 112 | 85 | 139 |
| 20P GAIN MUTATED | 18 | 35 | 34 | 14 |
| 20P GAIN WILD-TYPE | 117 | 77 | 51 | 125 |
Figure S172. Get High-res Image Gene #36: '20p gain' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 6.5e-05
Table S173. Gene #36: '20p gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 111 | 221 | 193 |
| 20P GAIN MUTATED | 18 | 18 | 76 |
| 20P GAIN WILD-TYPE | 93 | 203 | 117 |
Figure S173. Get High-res Image Gene #36: '20p gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 6.5e-05
Table S174. Gene #36: '20p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 117 | 33 | 183 | 132 | 35 | 25 |
| 20P GAIN MUTATED | 20 | 4 | 13 | 66 | 3 | 6 |
| 20P GAIN WILD-TYPE | 97 | 29 | 170 | 66 | 32 | 19 |
Figure S174. Get High-res Image Gene #36: '20p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 6.5e-05
Table S175. Gene #36: '20p gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 124 | 204 | 182 |
| 20P GAIN MUTATED | 25 | 18 | 68 |
| 20P GAIN WILD-TYPE | 99 | 186 | 114 |
Figure S175. Get High-res Image Gene #36: '20p gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 6.5e-05
Table S176. Gene #36: '20p gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 144 | 134 | 195 | 37 |
| 20P GAIN MUTATED | 36 | 33 | 22 | 20 |
| 20P GAIN WILD-TYPE | 108 | 101 | 173 | 17 |
Figure S176. Get High-res Image Gene #36: '20p gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 2e-05 (Fisher's exact test), Q value = 0.00012
Table S177. Gene #36: '20p gain' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 38 | 21 | 48 | 35 |
| 20P GAIN MUTATED | 6 | 3 | 3 | 18 |
| 20P GAIN WILD-TYPE | 32 | 18 | 45 | 17 |
Figure S177. Get High-res Image Gene #36: '20p gain' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 0.0429 (Fisher's exact test), Q value = 0.096
Table S178. Gene #37: '20q gain' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 33 | 24 | 13 |
| 20Q GAIN MUTATED | 3 | 8 | 4 |
| 20Q GAIN WILD-TYPE | 30 | 16 | 9 |
Figure S178. Get High-res Image Gene #37: '20q gain' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 6.5e-05
Table S179. Gene #37: '20q gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 238 | 135 | 155 |
| 20Q GAIN MUTATED | 10 | 38 | 67 |
| 20Q GAIN WILD-TYPE | 228 | 97 | 88 |
Figure S179. Get High-res Image Gene #37: '20q gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 4e-05 (Fisher's exact test), Q value = 0.00022
Table S180. Gene #37: '20q gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 128 | 76 | 110 |
| 20Q GAIN MUTATED | 12 | 16 | 37 |
| 20Q GAIN WILD-TYPE | 116 | 60 | 73 |
Figure S180. Get High-res Image Gene #37: '20q gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 6.5e-05
Table S181. Gene #37: '20q gain' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 88 | 86 | 90 | 82 | 92 | 33 |
| 20Q GAIN MUTATED | 19 | 5 | 47 | 12 | 19 | 2 |
| 20Q GAIN WILD-TYPE | 69 | 81 | 43 | 70 | 73 | 31 |
Figure S181. Get High-res Image Gene #37: '20q gain' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 6.5e-05
Table S182. Gene #37: '20q gain' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 135 | 112 | 85 | 139 |
| 20Q GAIN MUTATED | 18 | 38 | 34 | 14 |
| 20Q GAIN WILD-TYPE | 117 | 74 | 51 | 125 |
Figure S182. Get High-res Image Gene #37: '20q gain' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 6.5e-05
Table S183. Gene #37: '20q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 111 | 221 | 193 |
| 20Q GAIN MUTATED | 17 | 18 | 80 |
| 20Q GAIN WILD-TYPE | 94 | 203 | 113 |
Figure S183. Get High-res Image Gene #37: '20q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 6.5e-05
Table S184. Gene #37: '20q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 117 | 33 | 183 | 132 | 35 | 25 |
| 20Q GAIN MUTATED | 20 | 4 | 13 | 69 | 3 | 6 |
| 20Q GAIN WILD-TYPE | 97 | 29 | 170 | 63 | 32 | 19 |
Figure S184. Get High-res Image Gene #37: '20q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 6.5e-05
Table S185. Gene #37: '20q gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 124 | 204 | 182 |
| 20Q GAIN MUTATED | 25 | 18 | 71 |
| 20Q GAIN WILD-TYPE | 99 | 186 | 111 |
Figure S185. Get High-res Image Gene #37: '20q gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 6.5e-05
Table S186. Gene #37: '20q gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 144 | 134 | 195 | 37 |
| 20Q GAIN MUTATED | 38 | 34 | 22 | 20 |
| 20Q GAIN WILD-TYPE | 106 | 100 | 173 | 17 |
Figure S186. Get High-res Image Gene #37: '20q gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 6.5e-05
Table S187. Gene #37: '20q gain' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 38 | 21 | 48 | 35 |
| 20Q GAIN MUTATED | 6 | 3 | 3 | 19 |
| 20Q GAIN WILD-TYPE | 32 | 18 | 45 | 16 |
Figure S187. Get High-res Image Gene #37: '20q gain' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 0.0326 (Fisher's exact test), Q value = 0.077
Table S188. Gene #37: '20q gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 39 | 56 | 47 |
| 20Q GAIN MUTATED | 8 | 18 | 5 |
| 20Q GAIN WILD-TYPE | 31 | 38 | 42 |
Figure S188. Get High-res Image Gene #37: '20q gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 6.5e-05
Table S189. Gene #38: '21q gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 238 | 135 | 155 |
| 21Q GAIN MUTATED | 12 | 7 | 31 |
| 21Q GAIN WILD-TYPE | 226 | 128 | 124 |
Figure S189. Get High-res Image Gene #38: '21q gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.00133 (Fisher's exact test), Q value = 0.005
Table S190. Gene #38: '21q gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 128 | 76 | 110 |
| 21Q GAIN MUTATED | 6 | 4 | 20 |
| 21Q GAIN WILD-TYPE | 122 | 72 | 90 |
Figure S190. Get High-res Image Gene #38: '21q gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.00025 (Fisher's exact test), Q value = 0.0011
Table S191. Gene #38: '21q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 111 | 221 | 193 |
| 21Q GAIN MUTATED | 7 | 11 | 32 |
| 21Q GAIN WILD-TYPE | 104 | 210 | 161 |
Figure S191. Get High-res Image Gene #38: '21q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 0.00322 (Fisher's exact test), Q value = 0.011
Table S192. Gene #38: '21q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 117 | 33 | 183 | 132 | 35 | 25 |
| 21Q GAIN MUTATED | 10 | 2 | 9 | 25 | 3 | 1 |
| 21Q GAIN WILD-TYPE | 107 | 31 | 174 | 107 | 32 | 24 |
Figure S192. Get High-res Image Gene #38: '21q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00315 (Fisher's exact test), Q value = 0.011
Table S193. Gene #38: '21q gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 124 | 204 | 182 |
| 21Q GAIN MUTATED | 9 | 12 | 29 |
| 21Q GAIN WILD-TYPE | 115 | 192 | 153 |
Figure S193. Get High-res Image Gene #38: '21q gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.0311 (Fisher's exact test), Q value = 0.074
Table S194. Gene #38: '21q gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 144 | 134 | 195 | 37 |
| 21Q GAIN MUTATED | 11 | 17 | 14 | 8 |
| 21Q GAIN WILD-TYPE | 133 | 117 | 181 | 29 |
Figure S194. Get High-res Image Gene #38: '21q gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 2e-05 (Fisher's exact test), Q value = 0.00012
Table S195. Gene #39: '22q gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 238 | 135 | 155 |
| 22Q GAIN MUTATED | 5 | 13 | 22 |
| 22Q GAIN WILD-TYPE | 233 | 122 | 133 |
Figure S195. Get High-res Image Gene #39: '22q gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.0164 (Fisher's exact test), Q value = 0.044
Table S196. Gene #39: '22q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 117 | 33 | 183 | 132 | 35 | 25 |
| 22Q GAIN MUTATED | 5 | 1 | 10 | 17 | 2 | 5 |
| 22Q GAIN WILD-TYPE | 112 | 32 | 173 | 115 | 33 | 20 |
Figure S196. Get High-res Image Gene #39: '22q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00586 (Fisher's exact test), Q value = 0.018
Table S197. Gene #40: 'xp gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 238 | 135 | 155 |
| XP GAIN MUTATED | 7 | 8 | 17 |
| XP GAIN WILD-TYPE | 231 | 127 | 138 |
Figure S197. Get High-res Image Gene #40: 'xp gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.00012 (Fisher's exact test), Q value = 6e-04
Table S198. Gene #40: 'xp gain' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 88 | 86 | 90 | 82 | 92 | 33 |
| XP GAIN MUTATED | 12 | 0 | 10 | 2 | 3 | 0 |
| XP GAIN WILD-TYPE | 76 | 86 | 80 | 80 | 89 | 33 |
Figure S198. Get High-res Image Gene #40: 'xp gain' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 0.0011 (Fisher's exact test), Q value = 0.0042
Table S199. Gene #40: 'xp gain' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 135 | 112 | 85 | 139 |
| XP GAIN MUTATED | 5 | 6 | 13 | 3 |
| XP GAIN WILD-TYPE | 130 | 106 | 72 | 136 |
Figure S199. Get High-res Image Gene #40: 'xp gain' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
P value = 0.016 (Fisher's exact test), Q value = 0.043
Table S200. Gene #40: 'xp gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 111 | 221 | 193 |
| XP GAIN MUTATED | 9 | 6 | 17 |
| XP GAIN WILD-TYPE | 102 | 215 | 176 |
Figure S200. Get High-res Image Gene #40: 'xp gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 0.00091 (Fisher's exact test), Q value = 0.0035
Table S201. Gene #40: 'xp gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 117 | 33 | 183 | 132 | 35 | 25 |
| XP GAIN MUTATED | 3 | 4 | 6 | 18 | 1 | 0 |
| XP GAIN WILD-TYPE | 114 | 29 | 177 | 114 | 34 | 25 |
Figure S201. Get High-res Image Gene #40: 'xp gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0226 (Fisher's exact test), Q value = 0.057
Table S202. Gene #41: 'xq gain' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 88 | 86 | 90 | 82 | 92 | 33 |
| XQ GAIN MUTATED | 9 | 1 | 9 | 4 | 3 | 0 |
| XQ GAIN WILD-TYPE | 79 | 85 | 81 | 78 | 89 | 33 |
Figure S202. Get High-res Image Gene #41: 'xq gain' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 0.00085 (Fisher's exact test), Q value = 0.0034
Table S203. Gene #42: '1p loss' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 33 | 24 | 13 |
| 1P LOSS MUTATED | 2 | 3 | 7 |
| 1P LOSS WILD-TYPE | 31 | 21 | 6 |
Figure S203. Get High-res Image Gene #42: '1p loss' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 0.00273 (Fisher's exact test), Q value = 0.0096
Table S204. Gene #42: '1p loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 11 | 12 | 4 | 11 | 13 | 9 | 10 |
| 1P LOSS MUTATED | 0 | 1 | 2 | 1 | 1 | 1 | 6 |
| 1P LOSS WILD-TYPE | 11 | 11 | 2 | 10 | 12 | 8 | 4 |
Figure S204. Get High-res Image Gene #42: '1p loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 6.5e-05
Table S205. Gene #42: '1p loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 238 | 135 | 155 |
| 1P LOSS MUTATED | 5 | 27 | 25 |
| 1P LOSS WILD-TYPE | 233 | 108 | 130 |
Figure S205. Get High-res Image Gene #42: '1p loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.00748 (Fisher's exact test), Q value = 0.023
Table S206. Gene #42: '1p loss' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 88 | 86 | 90 | 82 | 92 | 33 |
| 1P LOSS MUTATED | 18 | 6 | 9 | 9 | 3 | 4 |
| 1P LOSS WILD-TYPE | 70 | 80 | 81 | 73 | 89 | 29 |
Figure S206. Get High-res Image Gene #42: '1p loss' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 0.0193 (Fisher's exact test), Q value = 0.05
Table S207. Gene #42: '1p loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 135 | 112 | 85 | 139 |
| 1P LOSS MUTATED | 6 | 12 | 14 | 17 |
| 1P LOSS WILD-TYPE | 129 | 100 | 71 | 122 |
Figure S207. Get High-res Image Gene #42: '1p loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
P value = 4e-05 (Fisher's exact test), Q value = 0.00022
Table S208. Gene #42: '1p loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 117 | 33 | 183 | 132 | 35 | 25 |
| 1P LOSS MUTATED | 9 | 5 | 15 | 14 | 2 | 12 |
| 1P LOSS WILD-TYPE | 108 | 28 | 168 | 118 | 33 | 13 |
Figure S208. Get High-res Image Gene #42: '1p loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00796 (Fisher's exact test), Q value = 0.024
Table S209. Gene #42: '1p loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 124 | 204 | 182 |
| 1P LOSS MUTATED | 8 | 18 | 31 |
| 1P LOSS WILD-TYPE | 116 | 186 | 151 |
Figure S209. Get High-res Image Gene #42: '1p loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.0233 (Fisher's exact test), Q value = 0.058
Table S210. Gene #42: '1p loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 144 | 134 | 195 | 37 |
| 1P LOSS MUTATED | 11 | 25 | 18 | 3 |
| 1P LOSS WILD-TYPE | 133 | 109 | 177 | 34 |
Figure S210. Get High-res Image Gene #42: '1p loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0356 (Fisher's exact test), Q value = 0.082
Table S211. Gene #42: '1p loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 38 | 21 | 48 | 35 |
| 1P LOSS MUTATED | 5 | 0 | 2 | 7 |
| 1P LOSS WILD-TYPE | 33 | 21 | 46 | 28 |
Figure S211. Get High-res Image Gene #42: '1p loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 0.0102 (Fisher's exact test), Q value = 0.03
Table S212. Gene #43: '1q loss' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 33 | 24 | 13 |
| 1Q LOSS MUTATED | 2 | 1 | 5 |
| 1Q LOSS WILD-TYPE | 31 | 23 | 8 |
Figure S212. Get High-res Image Gene #43: '1q loss' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 0.0111 (Fisher's exact test), Q value = 0.032
Table S213. Gene #43: '1q loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 11 | 12 | 4 | 11 | 13 | 9 | 10 |
| 1Q LOSS MUTATED | 0 | 1 | 0 | 0 | 1 | 1 | 5 |
| 1Q LOSS WILD-TYPE | 11 | 11 | 4 | 11 | 12 | 8 | 5 |
Figure S213. Get High-res Image Gene #43: '1q loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 6.5e-05
Table S214. Gene #43: '1q loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 238 | 135 | 155 |
| 1Q LOSS MUTATED | 1 | 23 | 12 |
| 1Q LOSS WILD-TYPE | 237 | 112 | 143 |
Figure S214. Get High-res Image Gene #43: '1q loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.0362 (Fisher's exact test), Q value = 0.083
Table S215. Gene #43: '1q loss' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 88 | 86 | 90 | 82 | 92 | 33 |
| 1Q LOSS MUTATED | 12 | 4 | 8 | 3 | 2 | 2 |
| 1Q LOSS WILD-TYPE | 76 | 82 | 82 | 79 | 90 | 31 |
Figure S215. Get High-res Image Gene #43: '1q loss' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 0.00265 (Fisher's exact test), Q value = 0.0093
Table S216. Gene #43: '1q loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 135 | 112 | 85 | 139 |
| 1Q LOSS MUTATED | 3 | 10 | 12 | 6 |
| 1Q LOSS WILD-TYPE | 132 | 102 | 73 | 133 |
Figure S216. Get High-res Image Gene #43: '1q loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
P value = 0.00449 (Fisher's exact test), Q value = 0.015
Table S217. Gene #43: '1q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 111 | 221 | 193 |
| 1Q LOSS MUTATED | 16 | 10 | 10 |
| 1Q LOSS WILD-TYPE | 95 | 211 | 183 |
Figure S217. Get High-res Image Gene #43: '1q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 6.5e-05
Table S218. Gene #43: '1q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 117 | 33 | 183 | 132 | 35 | 25 |
| 1Q LOSS MUTATED | 5 | 1 | 7 | 10 | 2 | 11 |
| 1Q LOSS WILD-TYPE | 112 | 32 | 176 | 122 | 33 | 14 |
Figure S218. Get High-res Image Gene #43: '1q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00589 (Fisher's exact test), Q value = 0.018
Table S219. Gene #43: '1q loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 124 | 204 | 182 |
| 1Q LOSS MUTATED | 5 | 9 | 22 |
| 1Q LOSS WILD-TYPE | 119 | 195 | 160 |
Figure S219. Get High-res Image Gene #43: '1q loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.042 (Fisher's exact test), Q value = 0.094
Table S220. Gene #43: '1q loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 144 | 134 | 195 | 37 |
| 1Q LOSS MUTATED | 8 | 17 | 9 | 2 |
| 1Q LOSS WILD-TYPE | 136 | 117 | 186 | 35 |
Figure S220. Get High-res Image Gene #43: '1q loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 4e-05 (Fisher's exact test), Q value = 0.00022
Table S221. Gene #44: '2p loss' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 33 | 24 | 13 |
| 2P LOSS MUTATED | 0 | 1 | 6 |
| 2P LOSS WILD-TYPE | 33 | 23 | 7 |
Figure S221. Get High-res Image Gene #44: '2p loss' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 0.00061 (Fisher's exact test), Q value = 0.0025
Table S222. Gene #44: '2p loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 11 | 12 | 4 | 11 | 13 | 9 | 10 |
| 2P LOSS MUTATED | 0 | 1 | 1 | 0 | 0 | 0 | 5 |
| 2P LOSS WILD-TYPE | 11 | 11 | 3 | 11 | 13 | 9 | 5 |
Figure S222. Get High-res Image Gene #44: '2p loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 6.5e-05
Table S223. Gene #44: '2p loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 238 | 135 | 155 |
| 2P LOSS MUTATED | 0 | 12 | 2 |
| 2P LOSS WILD-TYPE | 238 | 123 | 153 |
Figure S223. Get High-res Image Gene #44: '2p loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.00079 (Fisher's exact test), Q value = 0.0032
Table S224. Gene #44: '2p loss' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 88 | 86 | 90 | 82 | 92 | 33 |
| 2P LOSS MUTATED | 7 | 0 | 2 | 0 | 0 | 0 |
| 2P LOSS WILD-TYPE | 81 | 86 | 88 | 82 | 92 | 33 |
Figure S224. Get High-res Image Gene #44: '2p loss' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 2e-04 (Fisher's exact test), Q value = 0.00097
Table S225. Gene #44: '2p loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 135 | 112 | 85 | 139 |
| 2P LOSS MUTATED | 0 | 1 | 7 | 1 |
| 2P LOSS WILD-TYPE | 135 | 111 | 78 | 138 |
Figure S225. Get High-res Image Gene #44: '2p loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 6.5e-05
Table S226. Gene #44: '2p loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 111 | 221 | 193 |
| 2P LOSS MUTATED | 12 | 0 | 2 |
| 2P LOSS WILD-TYPE | 99 | 221 | 191 |
Figure S226. Get High-res Image Gene #44: '2p loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 6.5e-05
Table S227. Gene #44: '2p loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 117 | 33 | 183 | 132 | 35 | 25 |
| 2P LOSS MUTATED | 0 | 2 | 1 | 2 | 0 | 9 |
| 2P LOSS WILD-TYPE | 117 | 31 | 182 | 130 | 35 | 16 |
Figure S227. Get High-res Image Gene #44: '2p loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 2e-05 (Fisher's exact test), Q value = 0.00012
Table S228. Gene #44: '2p loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 124 | 204 | 182 |
| 2P LOSS MUTATED | 1 | 0 | 13 |
| 2P LOSS WILD-TYPE | 123 | 204 | 169 |
Figure S228. Get High-res Image Gene #44: '2p loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 4e-05 (Fisher's exact test), Q value = 0.00022
Table S229. Gene #44: '2p loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 144 | 134 | 195 | 37 |
| 2P LOSS MUTATED | 1 | 12 | 1 | 0 |
| 2P LOSS WILD-TYPE | 143 | 122 | 194 | 37 |
Figure S229. Get High-res Image Gene #44: '2p loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00028 (Fisher's exact test), Q value = 0.0013
Table S230. Gene #45: '2q loss' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 33 | 24 | 13 |
| 2Q LOSS MUTATED | 0 | 1 | 5 |
| 2Q LOSS WILD-TYPE | 33 | 23 | 8 |
Figure S230. Get High-res Image Gene #45: '2q loss' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 0.00086 (Fisher's exact test), Q value = 0.0034
Table S231. Gene #45: '2q loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 11 | 12 | 4 | 11 | 13 | 9 | 10 |
| 2Q LOSS MUTATED | 0 | 1 | 0 | 0 | 0 | 0 | 5 |
| 2Q LOSS WILD-TYPE | 11 | 11 | 4 | 11 | 13 | 9 | 5 |
Figure S231. Get High-res Image Gene #45: '2q loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 6.5e-05
Table S232. Gene #45: '2q loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 238 | 135 | 155 |
| 2Q LOSS MUTATED | 0 | 11 | 3 |
| 2Q LOSS WILD-TYPE | 238 | 124 | 152 |
Figure S232. Get High-res Image Gene #45: '2q loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.00295 (Fisher's exact test), Q value = 0.01
Table S233. Gene #45: '2q loss' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 88 | 86 | 90 | 82 | 92 | 33 |
| 2Q LOSS MUTATED | 6 | 0 | 3 | 0 | 0 | 0 |
| 2Q LOSS WILD-TYPE | 82 | 86 | 87 | 82 | 92 | 33 |
Figure S233. Get High-res Image Gene #45: '2q loss' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 0.00024 (Fisher's exact test), Q value = 0.0011
Table S234. Gene #45: '2q loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 135 | 112 | 85 | 139 |
| 2Q LOSS MUTATED | 0 | 1 | 7 | 1 |
| 2Q LOSS WILD-TYPE | 135 | 111 | 78 | 138 |
Figure S234. Get High-res Image Gene #45: '2q loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 6.5e-05
Table S235. Gene #45: '2q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 111 | 221 | 193 |
| 2Q LOSS MUTATED | 12 | 0 | 2 |
| 2Q LOSS WILD-TYPE | 99 | 221 | 191 |
Figure S235. Get High-res Image Gene #45: '2q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 6.5e-05
Table S236. Gene #45: '2q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 117 | 33 | 183 | 132 | 35 | 25 |
| 2Q LOSS MUTATED | 0 | 1 | 1 | 3 | 0 | 9 |
| 2Q LOSS WILD-TYPE | 117 | 32 | 182 | 129 | 35 | 16 |
Figure S236. Get High-res Image Gene #45: '2q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 6.5e-05
Table S237. Gene #45: '2q loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 124 | 204 | 182 |
| 2Q LOSS MUTATED | 0 | 0 | 14 |
| 2Q LOSS WILD-TYPE | 124 | 204 | 168 |
Figure S237. Get High-res Image Gene #45: '2q loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 2e-05 (Fisher's exact test), Q value = 0.00012
Table S238. Gene #45: '2q loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 144 | 134 | 195 | 37 |
| 2Q LOSS MUTATED | 1 | 13 | 0 | 0 |
| 2Q LOSS WILD-TYPE | 143 | 121 | 195 | 37 |
Figure S238. Get High-res Image Gene #45: '2q loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.003 (Fisher's exact test), Q value = 0.01
Table S239. Gene #46: '3p loss' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 33 | 24 | 13 |
| 3P LOSS MUTATED | 22 | 19 | 3 |
| 3P LOSS WILD-TYPE | 11 | 5 | 10 |
Figure S239. Get High-res Image Gene #46: '3p loss' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 0.0103 (Fisher's exact test), Q value = 0.03
Table S240. Gene #46: '3p loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 11 | 12 | 4 | 11 | 13 | 9 | 10 |
| 3P LOSS MUTATED | 8 | 9 | 1 | 10 | 7 | 7 | 2 |
| 3P LOSS WILD-TYPE | 3 | 3 | 3 | 1 | 6 | 2 | 8 |
Figure S240. Get High-res Image Gene #46: '3p loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 6.5e-05
Table S241. Gene #46: '3p loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 238 | 135 | 155 |
| 3P LOSS MUTATED | 203 | 41 | 136 |
| 3P LOSS WILD-TYPE | 35 | 94 | 19 |
Figure S241. Get High-res Image Gene #46: '3p loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.00068 (Fisher's exact test), Q value = 0.0028
Table S242. Gene #46: '3p loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 128 | 76 | 110 |
| 3P LOSS MUTATED | 104 | 43 | 85 |
| 3P LOSS WILD-TYPE | 24 | 33 | 25 |
Figure S242. Get High-res Image Gene #46: '3p loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.0122 (Fisher's exact test), Q value = 0.034
Table S243. Gene #46: '3p loss' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 88 | 86 | 90 | 82 | 92 | 33 |
| 3P LOSS MUTATED | 52 | 70 | 64 | 65 | 62 | 26 |
| 3P LOSS WILD-TYPE | 36 | 16 | 26 | 17 | 30 | 7 |
Figure S243. Get High-res Image Gene #46: '3p loss' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 0.00034 (Fisher's exact test), Q value = 0.0015
Table S244. Gene #46: '3p loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 135 | 112 | 85 | 139 |
| 3P LOSS MUTATED | 95 | 90 | 46 | 108 |
| 3P LOSS WILD-TYPE | 40 | 22 | 39 | 31 |
Figure S244. Get High-res Image Gene #46: '3p loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 6.5e-05
Table S245. Gene #46: '3p loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 111 | 221 | 193 |
| 3P LOSS MUTATED | 54 | 183 | 141 |
| 3P LOSS WILD-TYPE | 57 | 38 | 52 |
Figure S245. Get High-res Image Gene #46: '3p loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 6.5e-05
Table S246. Gene #46: '3p loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 117 | 33 | 183 | 132 | 35 | 25 |
| 3P LOSS MUTATED | 93 | 14 | 148 | 96 | 25 | 2 |
| 3P LOSS WILD-TYPE | 24 | 19 | 35 | 36 | 10 | 23 |
Figure S246. Get High-res Image Gene #46: '3p loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0227 (Fisher's exact test), Q value = 0.057
Table S247. Gene #46: '3p loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 124 | 204 | 182 |
| 3P LOSS MUTATED | 84 | 160 | 122 |
| 3P LOSS WILD-TYPE | 40 | 44 | 60 |
Figure S247. Get High-res Image Gene #46: '3p loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.0086 (Fisher's exact test), Q value = 0.026
Table S248. Gene #46: '3p loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 144 | 134 | 195 | 37 |
| 3P LOSS MUTATED | 91 | 92 | 154 | 29 |
| 3P LOSS WILD-TYPE | 53 | 42 | 41 | 8 |
Figure S248. Get High-res Image Gene #46: '3p loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00143 (Fisher's exact test), Q value = 0.0053
Table S249. Gene #47: '3q loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 238 | 135 | 155 |
| 3Q LOSS MUTATED | 46 | 13 | 40 |
| 3Q LOSS WILD-TYPE | 192 | 122 | 115 |
Figure S249. Get High-res Image Gene #47: '3q loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.0192 (Fisher's exact test), Q value = 0.05
Table S250. Gene #47: '3q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 117 | 33 | 183 | 132 | 35 | 25 |
| 3Q LOSS MUTATED | 33 | 5 | 28 | 28 | 4 | 1 |
| 3Q LOSS WILD-TYPE | 84 | 28 | 155 | 104 | 31 | 24 |
Figure S250. Get High-res Image Gene #47: '3q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0273 (Fisher's exact test), Q value = 0.066
Table S251. Gene #47: '3q loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 144 | 134 | 195 | 37 |
| 3Q LOSS MUTATED | 19 | 27 | 38 | 13 |
| 3Q LOSS WILD-TYPE | 125 | 107 | 157 | 24 |
Figure S251. Get High-res Image Gene #47: '3q loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 6.5e-05
Table S252. Gene #48: '4p loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 238 | 135 | 155 |
| 4P LOSS MUTATED | 9 | 16 | 47 |
| 4P LOSS WILD-TYPE | 229 | 119 | 108 |
Figure S252. Get High-res Image Gene #48: '4p loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.00012 (Fisher's exact test), Q value = 6e-04
Table S253. Gene #48: '4p loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 128 | 76 | 110 |
| 4P LOSS MUTATED | 11 | 8 | 31 |
| 4P LOSS WILD-TYPE | 117 | 68 | 79 |
Figure S253. Get High-res Image Gene #48: '4p loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.00058 (Fisher's exact test), Q value = 0.0024
Table S254. Gene #48: '4p loss' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 88 | 86 | 90 | 82 | 92 | 33 |
| 4P LOSS MUTATED | 6 | 11 | 26 | 10 | 15 | 1 |
| 4P LOSS WILD-TYPE | 82 | 75 | 64 | 72 | 77 | 32 |
Figure S254. Get High-res Image Gene #48: '4p loss' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 0.00083 (Fisher's exact test), Q value = 0.0033
Table S255. Gene #48: '4p loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 111 | 221 | 193 |
| 4P LOSS MUTATED | 6 | 26 | 39 |
| 4P LOSS WILD-TYPE | 105 | 195 | 154 |
Figure S255. Get High-res Image Gene #48: '4p loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 0.00125 (Fisher's exact test), Q value = 0.0047
Table S256. Gene #48: '4p loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 117 | 33 | 183 | 132 | 35 | 25 |
| 4P LOSS MUTATED | 16 | 1 | 19 | 31 | 4 | 0 |
| 4P LOSS WILD-TYPE | 101 | 32 | 164 | 101 | 31 | 25 |
Figure S256. Get High-res Image Gene #48: '4p loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00695 (Fisher's exact test), Q value = 0.021
Table S257. Gene #48: '4p loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 39 | 56 | 47 |
| 4P LOSS MUTATED | 1 | 13 | 4 |
| 4P LOSS WILD-TYPE | 38 | 43 | 43 |
Figure S257. Get High-res Image Gene #48: '4p loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 6.5e-05
Table S258. Gene #49: '4q loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 238 | 135 | 155 |
| 4Q LOSS MUTATED | 5 | 14 | 46 |
| 4Q LOSS WILD-TYPE | 233 | 121 | 109 |
Figure S258. Get High-res Image Gene #49: '4q loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 2e-05 (Fisher's exact test), Q value = 0.00012
Table S259. Gene #49: '4q loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 128 | 76 | 110 |
| 4Q LOSS MUTATED | 9 | 6 | 30 |
| 4Q LOSS WILD-TYPE | 119 | 70 | 80 |
Figure S259. Get High-res Image Gene #49: '4q loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.00036 (Fisher's exact test), Q value = 0.0016
Table S260. Gene #49: '4q loss' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 88 | 86 | 90 | 82 | 92 | 33 |
| 4Q LOSS MUTATED | 7 | 8 | 26 | 9 | 12 | 1 |
| 4Q LOSS WILD-TYPE | 81 | 78 | 64 | 73 | 80 | 32 |
Figure S260. Get High-res Image Gene #49: '4q loss' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 0.017 (Fisher's exact test), Q value = 0.045
Table S261. Gene #49: '4q loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 135 | 112 | 85 | 139 |
| 4Q LOSS MUTATED | 12 | 21 | 17 | 13 |
| 4Q LOSS WILD-TYPE | 123 | 91 | 68 | 126 |
Figure S261. Get High-res Image Gene #49: '4q loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
P value = 0.00038 (Fisher's exact test), Q value = 0.0017
Table S262. Gene #49: '4q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 111 | 221 | 193 |
| 4Q LOSS MUTATED | 6 | 21 | 38 |
| 4Q LOSS WILD-TYPE | 105 | 200 | 155 |
Figure S262. Get High-res Image Gene #49: '4q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 3e-05 (Fisher's exact test), Q value = 0.00017
Table S263. Gene #49: '4q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 117 | 33 | 183 | 132 | 35 | 25 |
| 4Q LOSS MUTATED | 15 | 0 | 14 | 32 | 4 | 0 |
| 4Q LOSS WILD-TYPE | 102 | 33 | 169 | 100 | 31 | 25 |
Figure S263. Get High-res Image Gene #49: '4q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0163 (Fisher's exact test), Q value = 0.044
Table S264. Gene #50: '5p loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 238 | 135 | 155 |
| 5P LOSS MUTATED | 0 | 4 | 3 |
| 5P LOSS WILD-TYPE | 238 | 131 | 152 |
Figure S264. Get High-res Image Gene #50: '5p loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.0102 (Fisher's exact test), Q value = 0.03
Table S265. Gene #50: '5p loss' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 88 | 86 | 90 | 82 | 92 | 33 |
| 5P LOSS MUTATED | 0 | 0 | 5 | 0 | 1 | 0 |
| 5P LOSS WILD-TYPE | 88 | 86 | 85 | 82 | 91 | 33 |
Figure S265. Get High-res Image Gene #50: '5p loss' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 0.0265 (Fisher's exact test), Q value = 0.064
Table S266. Gene #50: '5p loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 111 | 221 | 193 |
| 5P LOSS MUTATED | 3 | 0 | 4 |
| 5P LOSS WILD-TYPE | 108 | 221 | 189 |
Figure S266. Get High-res Image Gene #50: '5p loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 0.011 (Fisher's exact test), Q value = 0.032
Table S267. Gene #50: '5p loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 117 | 33 | 183 | 132 | 35 | 25 |
| 5P LOSS MUTATED | 0 | 0 | 0 | 5 | 1 | 1 |
| 5P LOSS WILD-TYPE | 117 | 33 | 183 | 127 | 34 | 24 |
Figure S267. Get High-res Image Gene #50: '5p loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0423 (Fisher's exact test), Q value = 0.095
Table S268. Gene #50: '5p loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 124 | 204 | 182 |
| 5P LOSS MUTATED | 2 | 0 | 5 |
| 5P LOSS WILD-TYPE | 122 | 204 | 177 |
Figure S268. Get High-res Image Gene #50: '5p loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.0432 (Fisher's exact test), Q value = 0.096
Table S269. Gene #51: '5q loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 238 | 135 | 155 |
| 5Q LOSS MUTATED | 0 | 3 | 3 |
| 5Q LOSS WILD-TYPE | 238 | 132 | 152 |
Figure S269. Get High-res Image Gene #51: '5q loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.0432 (Fisher's exact test), Q value = 0.096
Table S270. Gene #51: '5q loss' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 88 | 86 | 90 | 82 | 92 | 33 |
| 5Q LOSS MUTATED | 0 | 0 | 4 | 0 | 1 | 0 |
| 5Q LOSS WILD-TYPE | 88 | 86 | 86 | 82 | 91 | 33 |
Figure S270. Get High-res Image Gene #51: '5q loss' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 0.0458 (Fisher's exact test), Q value = 0.1
Table S271. Gene #51: '5q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 111 | 221 | 193 |
| 5Q LOSS MUTATED | 3 | 0 | 3 |
| 5Q LOSS WILD-TYPE | 108 | 221 | 190 |
Figure S271. Get High-res Image Gene #51: '5q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 0.0151 (Fisher's exact test), Q value = 0.041
Table S272. Gene #51: '5q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 117 | 33 | 183 | 132 | 35 | 25 |
| 5Q LOSS MUTATED | 0 | 0 | 0 | 5 | 0 | 1 |
| 5Q LOSS WILD-TYPE | 117 | 33 | 183 | 127 | 35 | 24 |
Figure S272. Get High-res Image Gene #51: '5q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0107 (Fisher's exact test), Q value = 0.031
Table S273. Gene #52: '6p loss' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 33 | 24 | 13 |
| 6P LOSS MUTATED | 4 | 10 | 6 |
| 6P LOSS WILD-TYPE | 29 | 14 | 7 |
Figure S273. Get High-res Image Gene #52: '6p loss' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 0.0141 (Fisher's exact test), Q value = 0.039
Table S274. Gene #52: '6p loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 11 | 12 | 4 | 11 | 13 | 9 | 10 |
| 6P LOSS MUTATED | 2 | 7 | 0 | 3 | 1 | 1 | 6 |
| 6P LOSS WILD-TYPE | 9 | 5 | 4 | 8 | 12 | 8 | 4 |
Figure S274. Get High-res Image Gene #52: '6p loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 6.5e-05
Table S275. Gene #52: '6p loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 238 | 135 | 155 |
| 6P LOSS MUTATED | 11 | 26 | 63 |
| 6P LOSS WILD-TYPE | 227 | 109 | 92 |
Figure S275. Get High-res Image Gene #52: '6p loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 6e-05 (Fisher's exact test), Q value = 0.00032
Table S276. Gene #52: '6p loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 128 | 76 | 110 |
| 6P LOSS MUTATED | 9 | 12 | 31 |
| 6P LOSS WILD-TYPE | 119 | 64 | 79 |
Figure S276. Get High-res Image Gene #52: '6p loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 6.5e-05
Table S277. Gene #52: '6p loss' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 88 | 86 | 90 | 82 | 92 | 33 |
| 6P LOSS MUTATED | 16 | 9 | 37 | 17 | 7 | 4 |
| 6P LOSS WILD-TYPE | 72 | 77 | 53 | 65 | 85 | 29 |
Figure S277. Get High-res Image Gene #52: '6p loss' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 6.5e-05
Table S278. Gene #52: '6p loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 135 | 112 | 85 | 139 |
| 6P LOSS MUTATED | 10 | 40 | 27 | 13 |
| 6P LOSS WILD-TYPE | 125 | 72 | 58 | 126 |
Figure S278. Get High-res Image Gene #52: '6p loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 6.5e-05
Table S279. Gene #52: '6p loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 111 | 221 | 193 |
| 6P LOSS MUTATED | 17 | 20 | 61 |
| 6P LOSS WILD-TYPE | 94 | 201 | 132 |
Figure S279. Get High-res Image Gene #52: '6p loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 6.5e-05
Table S280. Gene #52: '6p loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 117 | 33 | 183 | 132 | 35 | 25 |
| 6P LOSS MUTATED | 19 | 1 | 12 | 51 | 6 | 9 |
| 6P LOSS WILD-TYPE | 98 | 32 | 171 | 81 | 29 | 16 |
Figure S280. Get High-res Image Gene #52: '6p loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 6.5e-05
Table S281. Gene #52: '6p loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 124 | 204 | 182 |
| 6P LOSS MUTATED | 14 | 17 | 65 |
| 6P LOSS WILD-TYPE | 110 | 187 | 117 |
Figure S281. Get High-res Image Gene #52: '6p loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 6.5e-05
Table S282. Gene #52: '6p loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 144 | 134 | 195 | 37 |
| 6P LOSS MUTATED | 26 | 40 | 14 | 16 |
| 6P LOSS WILD-TYPE | 118 | 94 | 181 | 21 |
Figure S282. Get High-res Image Gene #52: '6p loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0243 (Fisher's exact test), Q value = 0.06
Table S283. Gene #52: '6p loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 39 | 56 | 47 |
| 6P LOSS MUTATED | 4 | 14 | 3 |
| 6P LOSS WILD-TYPE | 35 | 42 | 44 |
Figure S283. Get High-res Image Gene #52: '6p loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 6.5e-05
Table S284. Gene #53: '6q loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 238 | 135 | 155 |
| 6Q LOSS MUTATED | 27 | 26 | 75 |
| 6Q LOSS WILD-TYPE | 211 | 109 | 80 |
Figure S284. Get High-res Image Gene #53: '6q loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.00577 (Fisher's exact test), Q value = 0.018
Table S285. Gene #53: '6q loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 128 | 76 | 110 |
| 6Q LOSS MUTATED | 19 | 14 | 35 |
| 6Q LOSS WILD-TYPE | 109 | 62 | 75 |
Figure S285. Get High-res Image Gene #53: '6q loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 6.5e-05
Table S286. Gene #53: '6q loss' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 88 | 86 | 90 | 82 | 92 | 33 |
| 6Q LOSS MUTATED | 18 | 21 | 39 | 25 | 7 | 5 |
| 6Q LOSS WILD-TYPE | 70 | 65 | 51 | 57 | 85 | 28 |
Figure S286. Get High-res Image Gene #53: '6q loss' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 6.5e-05
Table S287. Gene #53: '6q loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 135 | 112 | 85 | 139 |
| 6Q LOSS MUTATED | 13 | 45 | 29 | 28 |
| 6Q LOSS WILD-TYPE | 122 | 67 | 56 | 111 |
Figure S287. Get High-res Image Gene #53: '6q loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
P value = 0.00025 (Fisher's exact test), Q value = 0.0011
Table S288. Gene #53: '6q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 111 | 221 | 193 |
| 6Q LOSS MUTATED | 19 | 41 | 66 |
| 6Q LOSS WILD-TYPE | 92 | 180 | 127 |
Figure S288. Get High-res Image Gene #53: '6q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 8e-05 (Fisher's exact test), Q value = 0.00041
Table S289. Gene #53: '6q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 117 | 33 | 183 | 132 | 35 | 25 |
| 6Q LOSS MUTATED | 22 | 5 | 29 | 53 | 8 | 9 |
| 6Q LOSS WILD-TYPE | 95 | 28 | 154 | 79 | 27 | 16 |
Figure S289. Get High-res Image Gene #53: '6q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 6.5e-05
Table S290. Gene #53: '6q loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 124 | 204 | 182 |
| 6Q LOSS MUTATED | 20 | 33 | 71 |
| 6Q LOSS WILD-TYPE | 104 | 171 | 111 |
Figure S290. Get High-res Image Gene #53: '6q loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 4e-05 (Fisher's exact test), Q value = 0.00022
Table S291. Gene #53: '6q loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 144 | 134 | 195 | 37 |
| 6Q LOSS MUTATED | 31 | 46 | 30 | 17 |
| 6Q LOSS WILD-TYPE | 113 | 88 | 165 | 20 |
Figure S291. Get High-res Image Gene #53: '6q loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0259 (Fisher's exact test), Q value = 0.063
Table S292. Gene #53: '6q loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 39 | 56 | 47 |
| 6Q LOSS MUTATED | 5 | 18 | 6 |
| 6Q LOSS WILD-TYPE | 34 | 38 | 41 |
Figure S292. Get High-res Image Gene #53: '6q loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.0445 (Fisher's exact test), Q value = 0.098
Table S293. Gene #54: '7p loss' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 88 | 86 | 90 | 82 | 92 | 33 |
| 7P LOSS MUTATED | 0 | 0 | 3 | 0 | 0 | 0 |
| 7P LOSS WILD-TYPE | 88 | 86 | 87 | 82 | 92 | 33 |
Figure S293. Get High-res Image Gene #54: '7p loss' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 0.042 (Fisher's exact test), Q value = 0.094
Table S294. Gene #54: '7p loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 135 | 112 | 85 | 139 |
| 7P LOSS MUTATED | 0 | 1 | 2 | 0 |
| 7P LOSS WILD-TYPE | 135 | 111 | 83 | 139 |
Figure S294. Get High-res Image Gene #54: '7p loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
P value = 0.0107 (Fisher's exact test), Q value = 0.031
Table S295. Gene #55: '7q loss' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 88 | 86 | 90 | 82 | 92 | 33 |
| 7Q LOSS MUTATED | 0 | 0 | 4 | 0 | 0 | 0 |
| 7Q LOSS WILD-TYPE | 88 | 86 | 86 | 82 | 92 | 33 |
Figure S295. Get High-res Image Gene #55: '7q loss' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 0.0495 (Fisher's exact test), Q value = 0.11
Table S296. Gene #55: '7q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 111 | 221 | 193 |
| 7Q LOSS MUTATED | 0 | 0 | 4 |
| 7Q LOSS WILD-TYPE | 111 | 221 | 189 |
Figure S296. Get High-res Image Gene #55: '7q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 0.0193 (Fisher's exact test), Q value = 0.05
Table S297. Gene #55: '7q loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 124 | 204 | 182 |
| 7Q LOSS MUTATED | 0 | 0 | 4 |
| 7Q LOSS WILD-TYPE | 124 | 204 | 178 |
Figure S297. Get High-res Image Gene #55: '7q loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 6.5e-05
Table S298. Gene #56: '8p loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 238 | 135 | 155 |
| 8P LOSS MUTATED | 43 | 30 | 64 |
| 8P LOSS WILD-TYPE | 195 | 105 | 91 |
Figure S298. Get High-res Image Gene #56: '8p loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.00124 (Fisher's exact test), Q value = 0.0047
Table S299. Gene #56: '8p loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 117 | 33 | 183 | 132 | 35 | 25 |
| 8P LOSS MUTATED | 28 | 3 | 47 | 50 | 4 | 4 |
| 8P LOSS WILD-TYPE | 89 | 30 | 136 | 82 | 31 | 21 |
Figure S299. Get High-res Image Gene #56: '8p loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0417 (Fisher's exact test), Q value = 0.094
Table S300. Gene #56: '8p loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 124 | 204 | 182 |
| 8P LOSS MUTATED | 32 | 43 | 59 |
| 8P LOSS WILD-TYPE | 92 | 161 | 123 |
Figure S300. Get High-res Image Gene #56: '8p loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.0231 (Fisher's exact test), Q value = 0.058
Table S301. Gene #56: '8p loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 144 | 134 | 195 | 37 |
| 8P LOSS MUTATED | 44 | 33 | 41 | 16 |
| 8P LOSS WILD-TYPE | 100 | 101 | 154 | 21 |
Figure S301. Get High-res Image Gene #56: '8p loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0439 (Fisher's exact test), Q value = 0.097
Table S302. Gene #57: '8q loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 128 | 76 | 110 |
| 8Q LOSS MUTATED | 17 | 3 | 16 |
| 8Q LOSS WILD-TYPE | 111 | 73 | 94 |
Figure S302. Get High-res Image Gene #57: '8q loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.00377 (Fisher's exact test), Q value = 0.013
Table S303. Gene #58: '9p loss' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 33 | 24 | 13 |
| 9P LOSS MUTATED | 5 | 12 | 1 |
| 9P LOSS WILD-TYPE | 28 | 12 | 12 |
Figure S303. Get High-res Image Gene #58: '9p loss' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 0.0365 (Fisher's exact test), Q value = 0.084
Table S304. Gene #58: '9p loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 11 | 12 | 4 | 11 | 13 | 9 | 10 |
| 9P LOSS MUTATED | 2 | 7 | 0 | 5 | 1 | 2 | 1 |
| 9P LOSS WILD-TYPE | 9 | 5 | 4 | 6 | 12 | 7 | 9 |
Figure S304. Get High-res Image Gene #58: '9p loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 6.5e-05
Table S305. Gene #58: '9p loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 238 | 135 | 155 |
| 9P LOSS MUTATED | 10 | 32 | 107 |
| 9P LOSS WILD-TYPE | 228 | 103 | 48 |
Figure S305. Get High-res Image Gene #58: '9p loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 6.5e-05
Table S306. Gene #58: '9p loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 128 | 76 | 110 |
| 9P LOSS MUTATED | 6 | 20 | 67 |
| 9P LOSS WILD-TYPE | 122 | 56 | 43 |
Figure S306. Get High-res Image Gene #58: '9p loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 6.5e-05
Table S307. Gene #58: '9p loss' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 88 | 86 | 90 | 82 | 92 | 33 |
| 9P LOSS MUTATED | 16 | 15 | 54 | 22 | 25 | 6 |
| 9P LOSS WILD-TYPE | 72 | 71 | 36 | 60 | 67 | 27 |
Figure S307. Get High-res Image Gene #58: '9p loss' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 6.5e-05
Table S308. Gene #58: '9p loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 135 | 112 | 85 | 139 |
| 9P LOSS MUTATED | 25 | 52 | 36 | 25 |
| 9P LOSS WILD-TYPE | 110 | 60 | 49 | 114 |
Figure S308. Get High-res Image Gene #58: '9p loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 6.5e-05
Table S309. Gene #58: '9p loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 111 | 221 | 193 |
| 9P LOSS MUTATED | 16 | 26 | 106 |
| 9P LOSS WILD-TYPE | 95 | 195 | 87 |
Figure S309. Get High-res Image Gene #58: '9p loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 6.5e-05
Table S310. Gene #58: '9p loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 117 | 33 | 183 | 132 | 35 | 25 |
| 9P LOSS MUTATED | 31 | 2 | 16 | 82 | 13 | 4 |
| 9P LOSS WILD-TYPE | 86 | 31 | 167 | 50 | 22 | 21 |
Figure S310. Get High-res Image Gene #58: '9p loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 6.5e-05
Table S311. Gene #58: '9p loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 124 | 204 | 182 |
| 9P LOSS MUTATED | 27 | 26 | 91 |
| 9P LOSS WILD-TYPE | 97 | 178 | 91 |
Figure S311. Get High-res Image Gene #58: '9p loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 6.5e-05
Table S312. Gene #58: '9p loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 144 | 134 | 195 | 37 |
| 9P LOSS MUTATED | 43 | 53 | 24 | 24 |
| 9P LOSS WILD-TYPE | 101 | 81 | 171 | 13 |
Figure S312. Get High-res Image Gene #58: '9p loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0164 (Fisher's exact test), Q value = 0.044
Table S313. Gene #58: '9p loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 38 | 21 | 48 | 35 |
| 9P LOSS MUTATED | 8 | 4 | 5 | 14 |
| 9P LOSS WILD-TYPE | 30 | 17 | 43 | 21 |
Figure S313. Get High-res Image Gene #58: '9p loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 0.00921 (Fisher's exact test), Q value = 0.027
Table S314. Gene #59: '9q loss' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 33 | 24 | 13 |
| 9Q LOSS MUTATED | 5 | 12 | 2 |
| 9Q LOSS WILD-TYPE | 28 | 12 | 11 |
Figure S314. Get High-res Image Gene #59: '9q loss' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 6.5e-05
Table S315. Gene #59: '9q loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 238 | 135 | 155 |
| 9Q LOSS MUTATED | 11 | 32 | 107 |
| 9Q LOSS WILD-TYPE | 227 | 103 | 48 |
Figure S315. Get High-res Image Gene #59: '9q loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 6.5e-05
Table S316. Gene #59: '9q loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 128 | 76 | 110 |
| 9Q LOSS MUTATED | 6 | 21 | 64 |
| 9Q LOSS WILD-TYPE | 122 | 55 | 46 |
Figure S316. Get High-res Image Gene #59: '9q loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 6.5e-05
Table S317. Gene #59: '9q loss' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 88 | 86 | 90 | 82 | 92 | 33 |
| 9Q LOSS MUTATED | 18 | 14 | 52 | 24 | 26 | 5 |
| 9Q LOSS WILD-TYPE | 70 | 72 | 38 | 58 | 66 | 28 |
Figure S317. Get High-res Image Gene #59: '9q loss' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 6.5e-05
Table S318. Gene #59: '9q loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 135 | 112 | 85 | 139 |
| 9Q LOSS MUTATED | 26 | 52 | 36 | 25 |
| 9Q LOSS WILD-TYPE | 109 | 60 | 49 | 114 |
Figure S318. Get High-res Image Gene #59: '9q loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 6.5e-05
Table S319. Gene #59: '9q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 111 | 221 | 193 |
| 9Q LOSS MUTATED | 16 | 26 | 107 |
| 9Q LOSS WILD-TYPE | 95 | 195 | 86 |
Figure S319. Get High-res Image Gene #59: '9q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 6.5e-05
Table S320. Gene #59: '9q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 117 | 33 | 183 | 132 | 35 | 25 |
| 9Q LOSS MUTATED | 32 | 3 | 15 | 82 | 13 | 4 |
| 9Q LOSS WILD-TYPE | 85 | 30 | 168 | 50 | 22 | 21 |
Figure S320. Get High-res Image Gene #59: '9q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 6.5e-05
Table S321. Gene #59: '9q loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 124 | 204 | 182 |
| 9Q LOSS MUTATED | 26 | 25 | 93 |
| 9Q LOSS WILD-TYPE | 98 | 179 | 89 |
Figure S321. Get High-res Image Gene #59: '9q loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 6.5e-05
Table S322. Gene #59: '9q loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 144 | 134 | 195 | 37 |
| 9Q LOSS MUTATED | 42 | 55 | 23 | 24 |
| 9Q LOSS WILD-TYPE | 102 | 79 | 172 | 13 |
Figure S322. Get High-res Image Gene #59: '9q loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00357 (Fisher's exact test), Q value = 0.012
Table S323. Gene #59: '9q loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 38 | 21 | 48 | 35 |
| 9Q LOSS MUTATED | 6 | 4 | 6 | 16 |
| 9Q LOSS WILD-TYPE | 32 | 17 | 42 | 19 |
Figure S323. Get High-res Image Gene #59: '9q loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 0.037 (Fisher's exact test), Q value = 0.085
Table S324. Gene #59: '9q loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 39 | 56 | 47 |
| 9Q LOSS MUTATED | 6 | 19 | 7 |
| 9Q LOSS WILD-TYPE | 33 | 37 | 40 |
Figure S324. Get High-res Image Gene #59: '9q loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 6.5e-05
Table S325. Gene #60: '10p loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 238 | 135 | 155 |
| 10P LOSS MUTATED | 9 | 23 | 35 |
| 10P LOSS WILD-TYPE | 229 | 112 | 120 |
Figure S325. Get High-res Image Gene #60: '10p loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.0226 (Fisher's exact test), Q value = 0.057
Table S326. Gene #60: '10p loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 135 | 112 | 85 | 139 |
| 10P LOSS MUTATED | 9 | 17 | 17 | 16 |
| 10P LOSS WILD-TYPE | 126 | 95 | 68 | 123 |
Figure S326. Get High-res Image Gene #60: '10p loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
P value = 8e-04 (Fisher's exact test), Q value = 0.0032
Table S327. Gene #60: '10p loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 117 | 33 | 183 | 132 | 35 | 25 |
| 10P LOSS MUTATED | 16 | 3 | 13 | 24 | 2 | 9 |
| 10P LOSS WILD-TYPE | 101 | 30 | 170 | 108 | 33 | 16 |
Figure S327. Get High-res Image Gene #60: '10p loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.017 (Fisher's exact test), Q value = 0.045
Table S328. Gene #60: '10p loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 124 | 204 | 182 |
| 10P LOSS MUTATED | 15 | 17 | 33 |
| 10P LOSS WILD-TYPE | 109 | 187 | 149 |
Figure S328. Get High-res Image Gene #60: '10p loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 6.5e-05
Table S329. Gene #61: '10q loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 238 | 135 | 155 |
| 10Q LOSS MUTATED | 17 | 27 | 45 |
| 10Q LOSS WILD-TYPE | 221 | 108 | 110 |
Figure S329. Get High-res Image Gene #61: '10q loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.00421 (Fisher's exact test), Q value = 0.014
Table S330. Gene #61: '10q loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 128 | 76 | 110 |
| 10Q LOSS MUTATED | 17 | 8 | 30 |
| 10Q LOSS WILD-TYPE | 111 | 68 | 80 |
Figure S330. Get High-res Image Gene #61: '10q loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.0222 (Fisher's exact test), Q value = 0.056
Table S331. Gene #61: '10q loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 135 | 112 | 85 | 139 |
| 10Q LOSS MUTATED | 14 | 24 | 21 | 22 |
| 10Q LOSS WILD-TYPE | 121 | 88 | 64 | 117 |
Figure S331. Get High-res Image Gene #61: '10q loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
P value = 0.00198 (Fisher's exact test), Q value = 0.007
Table S332. Gene #61: '10q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 117 | 33 | 183 | 132 | 35 | 25 |
| 10Q LOSS MUTATED | 22 | 3 | 20 | 32 | 3 | 9 |
| 10Q LOSS WILD-TYPE | 95 | 30 | 163 | 100 | 32 | 16 |
Figure S332. Get High-res Image Gene #61: '10q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0383 (Fisher's exact test), Q value = 0.087
Table S333. Gene #61: '10q loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 124 | 204 | 182 |
| 10Q LOSS MUTATED | 20 | 26 | 41 |
| 10Q LOSS WILD-TYPE | 104 | 178 | 141 |
Figure S333. Get High-res Image Gene #61: '10q loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 5e-04 (Fisher's exact test), Q value = 0.0021
Table S334. Gene #61: '10q loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 144 | 134 | 195 | 37 |
| 10Q LOSS MUTATED | 20 | 32 | 22 | 13 |
| 10Q LOSS WILD-TYPE | 124 | 102 | 173 | 24 |
Figure S334. Get High-res Image Gene #61: '10q loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 6.5e-05
Table S335. Gene #62: '11p loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 238 | 135 | 155 |
| 11P LOSS MUTATED | 0 | 5 | 13 |
| 11P LOSS WILD-TYPE | 238 | 130 | 142 |
Figure S335. Get High-res Image Gene #62: '11p loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.0223 (Fisher's exact test), Q value = 0.057
Table S336. Gene #62: '11p loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 128 | 76 | 110 |
| 11P LOSS MUTATED | 1 | 3 | 8 |
| 11P LOSS WILD-TYPE | 127 | 73 | 102 |
Figure S336. Get High-res Image Gene #62: '11p loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.0273 (Fisher's exact test), Q value = 0.066
Table S337. Gene #62: '11p loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 117 | 33 | 183 | 132 | 35 | 25 |
| 11P LOSS MUTATED | 3 | 1 | 2 | 11 | 1 | 0 |
| 11P LOSS WILD-TYPE | 114 | 32 | 181 | 121 | 34 | 25 |
Figure S337. Get High-res Image Gene #62: '11p loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 6.5e-05
Table S338. Gene #63: '11q loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 238 | 135 | 155 |
| 11Q LOSS MUTATED | 0 | 5 | 18 |
| 11Q LOSS WILD-TYPE | 238 | 130 | 137 |
Figure S338. Get High-res Image Gene #63: '11q loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.00553 (Fisher's exact test), Q value = 0.018
Table S339. Gene #63: '11q loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 128 | 76 | 110 |
| 11Q LOSS MUTATED | 1 | 4 | 10 |
| 11Q LOSS WILD-TYPE | 127 | 72 | 100 |
Figure S339. Get High-res Image Gene #63: '11q loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.00966 (Fisher's exact test), Q value = 0.028
Table S340. Gene #63: '11q loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 135 | 112 | 85 | 139 |
| 11Q LOSS MUTATED | 2 | 10 | 6 | 3 |
| 11Q LOSS WILD-TYPE | 133 | 102 | 79 | 136 |
Figure S340. Get High-res Image Gene #63: '11q loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
P value = 0.014 (Fisher's exact test), Q value = 0.039
Table S341. Gene #63: '11q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 111 | 221 | 193 |
| 11Q LOSS MUTATED | 4 | 4 | 15 |
| 11Q LOSS WILD-TYPE | 107 | 217 | 178 |
Figure S341. Get High-res Image Gene #63: '11q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 0.00039 (Fisher's exact test), Q value = 0.0017
Table S342. Gene #63: '11q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 117 | 33 | 183 | 132 | 35 | 25 |
| 11Q LOSS MUTATED | 3 | 1 | 2 | 16 | 1 | 0 |
| 11Q LOSS WILD-TYPE | 114 | 32 | 181 | 116 | 34 | 25 |
Figure S342. Get High-res Image Gene #63: '11q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0229 (Fisher's exact test), Q value = 0.057
Table S343. Gene #63: '11q loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 124 | 204 | 182 |
| 11Q LOSS MUTATED | 5 | 4 | 14 |
| 11Q LOSS WILD-TYPE | 119 | 200 | 168 |
Figure S343. Get High-res Image Gene #63: '11q loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.0378 (Fisher's exact test), Q value = 0.086
Table S344. Gene #63: '11q loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 144 | 134 | 195 | 37 |
| 11Q LOSS MUTATED | 9 | 8 | 3 | 3 |
| 11Q LOSS WILD-TYPE | 135 | 126 | 192 | 34 |
Figure S344. Get High-res Image Gene #63: '11q loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0033 (Fisher's exact test), Q value = 0.011
Table S345. Gene #66: '13q loss' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 33 | 24 | 13 |
| 13Q LOSS MUTATED | 0 | 6 | 3 |
| 13Q LOSS WILD-TYPE | 33 | 18 | 10 |
Figure S345. Get High-res Image Gene #66: '13q loss' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 0.0468 (Fisher's exact test), Q value = 0.1
Table S346. Gene #66: '13q loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 11 | 12 | 4 | 11 | 13 | 9 | 10 |
| 13Q LOSS MUTATED | 0 | 3 | 0 | 3 | 0 | 0 | 3 |
| 13Q LOSS WILD-TYPE | 11 | 9 | 4 | 8 | 13 | 9 | 7 |
Figure S346. Get High-res Image Gene #66: '13q loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 6.5e-05
Table S347. Gene #66: '13q loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 238 | 135 | 155 |
| 13Q LOSS MUTATED | 7 | 23 | 41 |
| 13Q LOSS WILD-TYPE | 231 | 112 | 114 |
Figure S347. Get High-res Image Gene #66: '13q loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.00023 (Fisher's exact test), Q value = 0.0011
Table S348. Gene #66: '13q loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 128 | 76 | 110 |
| 13Q LOSS MUTATED | 7 | 15 | 24 |
| 13Q LOSS WILD-TYPE | 121 | 61 | 86 |
Figure S348. Get High-res Image Gene #66: '13q loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 6.5e-05
Table S349. Gene #66: '13q loss' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 88 | 86 | 90 | 82 | 92 | 33 |
| 13Q LOSS MUTATED | 11 | 2 | 30 | 9 | 9 | 2 |
| 13Q LOSS WILD-TYPE | 77 | 84 | 60 | 73 | 83 | 31 |
Figure S349. Get High-res Image Gene #66: '13q loss' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 2e-05 (Fisher's exact test), Q value = 0.00012
Table S350. Gene #66: '13q loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 135 | 112 | 85 | 139 |
| 13Q LOSS MUTATED | 9 | 22 | 22 | 10 |
| 13Q LOSS WILD-TYPE | 126 | 90 | 63 | 129 |
Figure S350. Get High-res Image Gene #66: '13q loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 6.5e-05
Table S351. Gene #66: '13q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 111 | 221 | 193 |
| 13Q LOSS MUTATED | 13 | 14 | 44 |
| 13Q LOSS WILD-TYPE | 98 | 207 | 149 |
Figure S351. Get High-res Image Gene #66: '13q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 6.5e-05
Table S352. Gene #66: '13q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 117 | 33 | 183 | 132 | 35 | 25 |
| 13Q LOSS MUTATED | 6 | 2 | 10 | 40 | 6 | 7 |
| 13Q LOSS WILD-TYPE | 111 | 31 | 173 | 92 | 29 | 18 |
Figure S352. Get High-res Image Gene #66: '13q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 6.5e-05
Table S353. Gene #66: '13q loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 124 | 204 | 182 |
| 13Q LOSS MUTATED | 12 | 12 | 45 |
| 13Q LOSS WILD-TYPE | 112 | 192 | 137 |
Figure S353. Get High-res Image Gene #66: '13q loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 6.5e-05
Table S354. Gene #66: '13q loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 144 | 134 | 195 | 37 |
| 13Q LOSS MUTATED | 17 | 31 | 9 | 12 |
| 13Q LOSS WILD-TYPE | 127 | 103 | 186 | 25 |
Figure S354. Get High-res Image Gene #66: '13q loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 4e-05 (Fisher's exact test), Q value = 0.00022
Table S355. Gene #67: '14q loss' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 33 | 24 | 13 |
| 14Q LOSS MUTATED | 9 | 19 | 2 |
| 14Q LOSS WILD-TYPE | 24 | 5 | 11 |
Figure S355. Get High-res Image Gene #67: '14q loss' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 6.5e-05
Table S356. Gene #67: '14q loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 11 | 12 | 4 | 11 | 13 | 9 | 10 |
| 14Q LOSS MUTATED | 4 | 7 | 1 | 11 | 5 | 0 | 2 |
| 14Q LOSS WILD-TYPE | 7 | 5 | 3 | 0 | 8 | 9 | 8 |
Figure S356. Get High-res Image Gene #67: '14q loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 6.5e-05
Table S357. Gene #67: '14q loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 238 | 135 | 155 |
| 14Q LOSS MUTATED | 63 | 45 | 108 |
| 14Q LOSS WILD-TYPE | 175 | 90 | 47 |
Figure S357. Get High-res Image Gene #67: '14q loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 6.5e-05
Table S358. Gene #67: '14q loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 128 | 76 | 110 |
| 14Q LOSS MUTATED | 25 | 34 | 64 |
| 14Q LOSS WILD-TYPE | 103 | 42 | 46 |
Figure S358. Get High-res Image Gene #67: '14q loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 6.5e-05
Table S359. Gene #67: '14q loss' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 88 | 86 | 90 | 82 | 92 | 33 |
| 14Q LOSS MUTATED | 29 | 22 | 57 | 53 | 31 | 6 |
| 14Q LOSS WILD-TYPE | 59 | 64 | 33 | 29 | 61 | 27 |
Figure S359. Get High-res Image Gene #67: '14q loss' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 0.0139 (Fisher's exact test), Q value = 0.038
Table S360. Gene #67: '14q loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 135 | 112 | 85 | 139 |
| 14Q LOSS MUTATED | 45 | 54 | 45 | 54 |
| 14Q LOSS WILD-TYPE | 90 | 58 | 40 | 85 |
Figure S360. Get High-res Image Gene #67: '14q loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 6.5e-05
Table S361. Gene #67: '14q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 111 | 221 | 193 |
| 14Q LOSS MUTATED | 17 | 69 | 127 |
| 14Q LOSS WILD-TYPE | 94 | 152 | 66 |
Figure S361. Get High-res Image Gene #67: '14q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 6.5e-05
Table S362. Gene #67: '14q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 117 | 33 | 183 | 132 | 35 | 25 |
| 14Q LOSS MUTATED | 41 | 7 | 52 | 79 | 32 | 2 |
| 14Q LOSS WILD-TYPE | 76 | 26 | 131 | 53 | 3 | 23 |
Figure S362. Get High-res Image Gene #67: '14q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 6.5e-05
Table S363. Gene #67: '14q loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 124 | 204 | 182 |
| 14Q LOSS MUTATED | 34 | 61 | 115 |
| 14Q LOSS WILD-TYPE | 90 | 143 | 67 |
Figure S363. Get High-res Image Gene #67: '14q loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 6.5e-05
Table S364. Gene #67: '14q loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 144 | 134 | 195 | 37 |
| 14Q LOSS MUTATED | 49 | 80 | 58 | 23 |
| 14Q LOSS WILD-TYPE | 95 | 54 | 137 | 14 |
Figure S364. Get High-res Image Gene #67: '14q loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 6.5e-05
Table S365. Gene #68: '15q loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 238 | 135 | 155 |
| 15Q LOSS MUTATED | 1 | 6 | 29 |
| 15Q LOSS WILD-TYPE | 237 | 129 | 126 |
Figure S365. Get High-res Image Gene #68: '15q loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.00068 (Fisher's exact test), Q value = 0.0028
Table S366. Gene #68: '15q loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 128 | 76 | 110 |
| 15Q LOSS MUTATED | 3 | 3 | 16 |
| 15Q LOSS WILD-TYPE | 125 | 73 | 94 |
Figure S366. Get High-res Image Gene #68: '15q loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.00969 (Fisher's exact test), Q value = 0.028
Table S367. Gene #68: '15q loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 135 | 112 | 85 | 139 |
| 15Q LOSS MUTATED | 5 | 15 | 9 | 6 |
| 15Q LOSS WILD-TYPE | 130 | 97 | 76 | 133 |
Figure S367. Get High-res Image Gene #68: '15q loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 6.5e-05
Table S368. Gene #68: '15q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 111 | 221 | 193 |
| 15Q LOSS MUTATED | 2 | 7 | 27 |
| 15Q LOSS WILD-TYPE | 109 | 214 | 166 |
Figure S368. Get High-res Image Gene #68: '15q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 6.5e-05
Table S369. Gene #68: '15q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 117 | 33 | 183 | 132 | 35 | 25 |
| 15Q LOSS MUTATED | 5 | 0 | 5 | 24 | 2 | 0 |
| 15Q LOSS WILD-TYPE | 112 | 33 | 178 | 108 | 33 | 25 |
Figure S369. Get High-res Image Gene #68: '15q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00089 (Fisher's exact test), Q value = 0.0035
Table S370. Gene #68: '15q loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 124 | 204 | 182 |
| 15Q LOSS MUTATED | 7 | 6 | 23 |
| 15Q LOSS WILD-TYPE | 117 | 198 | 159 |
Figure S370. Get High-res Image Gene #68: '15q loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.016 (Fisher's exact test), Q value = 0.043
Table S371. Gene #68: '15q loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 144 | 134 | 195 | 37 |
| 15Q LOSS MUTATED | 14 | 11 | 6 | 5 |
| 15Q LOSS WILD-TYPE | 130 | 123 | 189 | 32 |
Figure S371. Get High-res Image Gene #68: '15q loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0487 (Fisher's exact test), Q value = 0.11
Table S372. Gene #69: '16p loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 135 | 112 | 85 | 139 |
| 16P LOSS MUTATED | 0 | 3 | 4 | 2 |
| 16P LOSS WILD-TYPE | 135 | 109 | 81 | 137 |
Figure S372. Get High-res Image Gene #69: '16p loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
P value = 0.0379 (Fisher's exact test), Q value = 0.086
Table S373. Gene #70: '16q loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 238 | 135 | 155 |
| 16Q LOSS MUTATED | 3 | 4 | 9 |
| 16Q LOSS WILD-TYPE | 235 | 131 | 146 |
Figure S373. Get High-res Image Gene #70: '16q loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.00867 (Fisher's exact test), Q value = 0.026
Table S374. Gene #70: '16q loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 144 | 134 | 195 | 37 |
| 16Q LOSS MUTATED | 4 | 3 | 3 | 5 |
| 16Q LOSS WILD-TYPE | 140 | 131 | 192 | 32 |
Figure S374. Get High-res Image Gene #70: '16q loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.028 (Fisher's exact test), Q value = 0.067
Table S375. Gene #70: '16q loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 39 | 56 | 47 |
| 16Q LOSS MUTATED | 1 | 6 | 0 |
| 16Q LOSS WILD-TYPE | 38 | 50 | 47 |
Figure S375. Get High-res Image Gene #70: '16q loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 7e-05 (Fisher's exact test), Q value = 0.00037
Table S376. Gene #71: '17p loss' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 33 | 24 | 13 |
| 17P LOSS MUTATED | 0 | 5 | 6 |
| 17P LOSS WILD-TYPE | 33 | 19 | 7 |
Figure S376. Get High-res Image Gene #71: '17p loss' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 0.00024 (Fisher's exact test), Q value = 0.0011
Table S377. Gene #71: '17p loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 11 | 12 | 4 | 11 | 13 | 9 | 10 |
| 17P LOSS MUTATED | 0 | 5 | 1 | 0 | 0 | 0 | 5 |
| 17P LOSS WILD-TYPE | 11 | 7 | 3 | 11 | 13 | 9 | 5 |
Figure S377. Get High-res Image Gene #71: '17p loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 6.5e-05
Table S378. Gene #71: '17p loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 238 | 135 | 155 |
| 17P LOSS MUTATED | 2 | 16 | 28 |
| 17P LOSS WILD-TYPE | 236 | 119 | 127 |
Figure S378. Get High-res Image Gene #71: '17p loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.00045 (Fisher's exact test), Q value = 0.0019
Table S379. Gene #71: '17p loss' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 88 | 86 | 90 | 82 | 92 | 33 |
| 17P LOSS MUTATED | 13 | 2 | 16 | 3 | 5 | 1 |
| 17P LOSS WILD-TYPE | 75 | 84 | 74 | 79 | 87 | 32 |
Figure S379. Get High-res Image Gene #71: '17p loss' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 6.5e-05
Table S380. Gene #71: '17p loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 135 | 112 | 85 | 139 |
| 17P LOSS MUTATED | 6 | 11 | 19 | 4 |
| 17P LOSS WILD-TYPE | 129 | 101 | 66 | 135 |
Figure S380. Get High-res Image Gene #71: '17p loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 6.5e-05
Table S381. Gene #71: '17p loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 111 | 221 | 193 |
| 17P LOSS MUTATED | 15 | 3 | 28 |
| 17P LOSS WILD-TYPE | 96 | 218 | 165 |
Figure S381. Get High-res Image Gene #71: '17p loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 6.5e-05
Table S382. Gene #71: '17p loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 117 | 33 | 183 | 132 | 35 | 25 |
| 17P LOSS MUTATED | 6 | 3 | 3 | 23 | 2 | 9 |
| 17P LOSS WILD-TYPE | 111 | 30 | 180 | 109 | 33 | 16 |
Figure S382. Get High-res Image Gene #71: '17p loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 6.5e-05
Table S383. Gene #71: '17p loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 124 | 204 | 182 |
| 17P LOSS MUTATED | 9 | 4 | 33 |
| 17P LOSS WILD-TYPE | 115 | 200 | 149 |
Figure S383. Get High-res Image Gene #71: '17p loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.00022 (Fisher's exact test), Q value = 0.0011
Table S384. Gene #71: '17p loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 144 | 134 | 195 | 37 |
| 17P LOSS MUTATED | 13 | 20 | 6 | 7 |
| 17P LOSS WILD-TYPE | 131 | 114 | 189 | 30 |
Figure S384. Get High-res Image Gene #71: '17p loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00051 (Fisher's exact test), Q value = 0.0021
Table S385. Gene #72: '17q loss' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 33 | 24 | 13 |
| 17Q LOSS MUTATED | 0 | 4 | 5 |
| 17Q LOSS WILD-TYPE | 33 | 20 | 8 |
Figure S385. Get High-res Image Gene #72: '17q loss' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 0.00032 (Fisher's exact test), Q value = 0.0015
Table S386. Gene #72: '17q loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 11 | 12 | 4 | 11 | 13 | 9 | 10 |
| 17Q LOSS MUTATED | 0 | 4 | 0 | 0 | 0 | 0 | 5 |
| 17Q LOSS WILD-TYPE | 11 | 8 | 4 | 11 | 13 | 9 | 5 |
Figure S386. Get High-res Image Gene #72: '17q loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 6.5e-05
Table S387. Gene #72: '17q loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 238 | 135 | 155 |
| 17Q LOSS MUTATED | 1 | 13 | 14 |
| 17Q LOSS WILD-TYPE | 237 | 122 | 141 |
Figure S387. Get High-res Image Gene #72: '17q loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.00278 (Fisher's exact test), Q value = 0.0097
Table S388. Gene #72: '17q loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 135 | 112 | 85 | 139 |
| 17Q LOSS MUTATED | 3 | 5 | 11 | 3 |
| 17Q LOSS WILD-TYPE | 132 | 107 | 74 | 136 |
Figure S388. Get High-res Image Gene #72: '17q loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
P value = 7e-05 (Fisher's exact test), Q value = 0.00037
Table S389. Gene #72: '17q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 111 | 221 | 193 |
| 17Q LOSS MUTATED | 12 | 2 | 14 |
| 17Q LOSS WILD-TYPE | 99 | 219 | 179 |
Figure S389. Get High-res Image Gene #72: '17q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 6.5e-05
Table S390. Gene #72: '17q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 117 | 33 | 183 | 132 | 35 | 25 |
| 17Q LOSS MUTATED | 4 | 1 | 2 | 11 | 1 | 9 |
| 17Q LOSS WILD-TYPE | 113 | 32 | 181 | 121 | 34 | 16 |
Figure S390. Get High-res Image Gene #72: '17q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 6.5e-05
Table S391. Gene #72: '17q loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 124 | 204 | 182 |
| 17Q LOSS MUTATED | 4 | 2 | 22 |
| 17Q LOSS WILD-TYPE | 120 | 202 | 160 |
Figure S391. Get High-res Image Gene #72: '17q loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.00512 (Fisher's exact test), Q value = 0.016
Table S392. Gene #72: '17q loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 144 | 134 | 195 | 37 |
| 17Q LOSS MUTATED | 5 | 15 | 5 | 3 |
| 17Q LOSS WILD-TYPE | 139 | 119 | 190 | 34 |
Figure S392. Get High-res Image Gene #72: '17q loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 6.5e-05
Table S393. Gene #73: '18p loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 238 | 135 | 155 |
| 18P LOSS MUTATED | 12 | 25 | 56 |
| 18P LOSS WILD-TYPE | 226 | 110 | 99 |
Figure S393. Get High-res Image Gene #73: '18p loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 6.5e-05
Table S394. Gene #73: '18p loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 128 | 76 | 110 |
| 18P LOSS MUTATED | 6 | 19 | 32 |
| 18P LOSS WILD-TYPE | 122 | 57 | 78 |
Figure S394. Get High-res Image Gene #73: '18p loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 6.5e-05
Table S395. Gene #73: '18p loss' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 88 | 86 | 90 | 82 | 92 | 33 |
| 18P LOSS MUTATED | 13 | 4 | 37 | 15 | 11 | 3 |
| 18P LOSS WILD-TYPE | 75 | 82 | 53 | 67 | 81 | 30 |
Figure S395. Get High-res Image Gene #73: '18p loss' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 6.5e-05
Table S396. Gene #73: '18p loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 135 | 112 | 85 | 139 |
| 18P LOSS MUTATED | 10 | 33 | 25 | 15 |
| 18P LOSS WILD-TYPE | 125 | 79 | 60 | 124 |
Figure S396. Get High-res Image Gene #73: '18p loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 6.5e-05
Table S397. Gene #73: '18p loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 111 | 221 | 193 |
| 18P LOSS MUTATED | 9 | 11 | 72 |
| 18P LOSS WILD-TYPE | 102 | 210 | 121 |
Figure S397. Get High-res Image Gene #73: '18p loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 6.5e-05
Table S398. Gene #73: '18p loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 117 | 33 | 183 | 132 | 35 | 25 |
| 18P LOSS MUTATED | 10 | 5 | 9 | 55 | 10 | 3 |
| 18P LOSS WILD-TYPE | 107 | 28 | 174 | 77 | 25 | 22 |
Figure S398. Get High-res Image Gene #73: '18p loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 6.5e-05
Table S399. Gene #73: '18p loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 124 | 204 | 182 |
| 18P LOSS MUTATED | 21 | 11 | 61 |
| 18P LOSS WILD-TYPE | 103 | 193 | 121 |
Figure S399. Get High-res Image Gene #73: '18p loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 6.5e-05
Table S400. Gene #73: '18p loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 144 | 134 | 195 | 37 |
| 18P LOSS MUTATED | 29 | 40 | 9 | 15 |
| 18P LOSS WILD-TYPE | 115 | 94 | 186 | 22 |
Figure S400. Get High-res Image Gene #73: '18p loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00025 (Fisher's exact test), Q value = 0.0011
Table S401. Gene #73: '18p loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 38 | 21 | 48 | 35 |
| 18P LOSS MUTATED | 7 | 4 | 0 | 10 |
| 18P LOSS WILD-TYPE | 31 | 17 | 48 | 25 |
Figure S401. Get High-res Image Gene #73: '18p loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 0.0045 (Fisher's exact test), Q value = 0.015
Table S402. Gene #73: '18p loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 39 | 56 | 47 |
| 18P LOSS MUTATED | 7 | 13 | 1 |
| 18P LOSS WILD-TYPE | 32 | 43 | 46 |
Figure S402. Get High-res Image Gene #73: '18p loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.0462 (Fisher's exact test), Q value = 0.1
Table S403. Gene #74: '18q loss' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 33 | 24 | 13 |
| 18Q LOSS MUTATED | 2 | 7 | 3 |
| 18Q LOSS WILD-TYPE | 31 | 17 | 10 |
Figure S403. Get High-res Image Gene #74: '18q loss' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 6.5e-05
Table S404. Gene #74: '18q loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 238 | 135 | 155 |
| 18Q LOSS MUTATED | 13 | 25 | 57 |
| 18Q LOSS WILD-TYPE | 225 | 110 | 98 |
Figure S404. Get High-res Image Gene #74: '18q loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 6.5e-05
Table S405. Gene #74: '18q loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 128 | 76 | 110 |
| 18Q LOSS MUTATED | 7 | 19 | 31 |
| 18Q LOSS WILD-TYPE | 121 | 57 | 79 |
Figure S405. Get High-res Image Gene #74: '18q loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 6.5e-05
Table S406. Gene #74: '18q loss' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 88 | 86 | 90 | 82 | 92 | 33 |
| 18Q LOSS MUTATED | 14 | 6 | 37 | 14 | 12 | 3 |
| 18Q LOSS WILD-TYPE | 74 | 80 | 53 | 68 | 80 | 30 |
Figure S406. Get High-res Image Gene #74: '18q loss' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 6.5e-05
Table S407. Gene #74: '18q loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 135 | 112 | 85 | 139 |
| 18Q LOSS MUTATED | 12 | 33 | 25 | 16 |
| 18Q LOSS WILD-TYPE | 123 | 79 | 60 | 123 |
Figure S407. Get High-res Image Gene #74: '18q loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 6.5e-05
Table S408. Gene #74: '18q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 111 | 221 | 193 |
| 18Q LOSS MUTATED | 10 | 12 | 72 |
| 18Q LOSS WILD-TYPE | 101 | 209 | 121 |
Figure S408. Get High-res Image Gene #74: '18q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 6.5e-05
Table S409. Gene #74: '18q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 117 | 33 | 183 | 132 | 35 | 25 |
| 18Q LOSS MUTATED | 10 | 6 | 10 | 55 | 10 | 3 |
| 18Q LOSS WILD-TYPE | 107 | 27 | 173 | 77 | 25 | 22 |
Figure S409. Get High-res Image Gene #74: '18q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 6.5e-05
Table S410. Gene #74: '18q loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 124 | 204 | 182 |
| 18Q LOSS MUTATED | 22 | 12 | 61 |
| 18Q LOSS WILD-TYPE | 102 | 192 | 121 |
Figure S410. Get High-res Image Gene #74: '18q loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 6.5e-05
Table S411. Gene #74: '18q loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 144 | 134 | 195 | 37 |
| 18Q LOSS MUTATED | 28 | 41 | 10 | 16 |
| 18Q LOSS WILD-TYPE | 116 | 93 | 185 | 21 |
Figure S411. Get High-res Image Gene #74: '18q loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00336 (Fisher's exact test), Q value = 0.011
Table S412. Gene #74: '18q loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 38 | 21 | 48 | 35 |
| 18Q LOSS MUTATED | 7 | 3 | 1 | 10 |
| 18Q LOSS WILD-TYPE | 31 | 18 | 47 | 25 |
Figure S412. Get High-res Image Gene #74: '18q loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 0.0308 (Fisher's exact test), Q value = 0.074
Table S413. Gene #74: '18q loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 39 | 56 | 47 |
| 18Q LOSS MUTATED | 7 | 12 | 2 |
| 18Q LOSS WILD-TYPE | 32 | 44 | 45 |
Figure S413. Get High-res Image Gene #74: '18q loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 2e-05 (Fisher's exact test), Q value = 0.00012
Table S414. Gene #75: '19p loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 238 | 135 | 155 |
| 19P LOSS MUTATED | 0 | 1 | 10 |
| 19P LOSS WILD-TYPE | 238 | 134 | 145 |
Figure S414. Get High-res Image Gene #75: '19p loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.0322 (Fisher's exact test), Q value = 0.076
Table S415. Gene #75: '19p loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 128 | 76 | 110 |
| 19P LOSS MUTATED | 0 | 2 | 5 |
| 19P LOSS WILD-TYPE | 128 | 74 | 105 |
Figure S415. Get High-res Image Gene #75: '19p loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.00015 (Fisher's exact test), Q value = 0.00073
Table S416. Gene #75: '19p loss' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 88 | 86 | 90 | 82 | 92 | 33 |
| 19P LOSS MUTATED | 0 | 0 | 8 | 2 | 0 | 0 |
| 19P LOSS WILD-TYPE | 88 | 86 | 82 | 80 | 92 | 33 |
Figure S416. Get High-res Image Gene #75: '19p loss' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 0.00177 (Fisher's exact test), Q value = 0.0064
Table S417. Gene #75: '19p loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 135 | 112 | 85 | 139 |
| 19P LOSS MUTATED | 0 | 3 | 6 | 1 |
| 19P LOSS WILD-TYPE | 135 | 109 | 79 | 138 |
Figure S417. Get High-res Image Gene #75: '19p loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
P value = 0.0108 (Fisher's exact test), Q value = 0.031
Table S418. Gene #75: '19p loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 117 | 33 | 183 | 132 | 35 | 25 |
| 19P LOSS MUTATED | 1 | 0 | 1 | 9 | 0 | 0 |
| 19P LOSS WILD-TYPE | 116 | 33 | 182 | 123 | 35 | 25 |
Figure S418. Get High-res Image Gene #75: '19p loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00939 (Fisher's exact test), Q value = 0.028
Table S419. Gene #75: '19p loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 144 | 134 | 195 | 37 |
| 19P LOSS MUTATED | 5 | 4 | 0 | 2 |
| 19P LOSS WILD-TYPE | 139 | 130 | 195 | 35 |
Figure S419. Get High-res Image Gene #75: '19p loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0335 (Fisher's exact test), Q value = 0.078
Table S420. Gene #75: '19p loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 38 | 21 | 48 | 35 |
| 19P LOSS MUTATED | 0 | 1 | 0 | 3 |
| 19P LOSS WILD-TYPE | 38 | 20 | 48 | 32 |
Figure S420. Get High-res Image Gene #75: '19p loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 0.0374 (Fisher's exact test), Q value = 0.085
Table S421. Gene #75: '19p loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 39 | 56 | 47 |
| 19P LOSS MUTATED | 0 | 4 | 0 |
| 19P LOSS WILD-TYPE | 39 | 52 | 47 |
Figure S421. Get High-res Image Gene #75: '19p loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.0118 (Fisher's exact test), Q value = 0.033
Table S422. Gene #76: '19q loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 238 | 135 | 155 |
| 19Q LOSS MUTATED | 0 | 0 | 4 |
| 19Q LOSS WILD-TYPE | 238 | 135 | 151 |
Figure S422. Get High-res Image Gene #76: '19q loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.0193 (Fisher's exact test), Q value = 0.05
Table S423. Gene #77: '20p loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 124 | 204 | 182 |
| 20P LOSS MUTATED | 2 | 0 | 6 |
| 20P LOSS WILD-TYPE | 122 | 204 | 176 |
Figure S423. Get High-res Image Gene #77: '20p loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.0294 (Fisher's exact test), Q value = 0.07
Table S424. Gene #78: '20q loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 144 | 134 | 195 | 37 |
| 20Q LOSS MUTATED | 0 | 2 | 0 | 1 |
| 20Q LOSS WILD-TYPE | 144 | 132 | 195 | 36 |
Figure S424. Get High-res Image Gene #78: '20q loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0256 (Fisher's exact test), Q value = 0.063
Table S425. Gene #79: '21q loss' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 33 | 24 | 13 |
| 21Q LOSS MUTATED | 1 | 2 | 4 |
| 21Q LOSS WILD-TYPE | 32 | 22 | 9 |
Figure S425. Get High-res Image Gene #79: '21q loss' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 6.5e-05
Table S426. Gene #79: '21q loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 238 | 135 | 155 |
| 21Q LOSS MUTATED | 6 | 26 | 23 |
| 21Q LOSS WILD-TYPE | 232 | 109 | 132 |
Figure S426. Get High-res Image Gene #79: '21q loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.0137 (Fisher's exact test), Q value = 0.038
Table S427. Gene #79: '21q loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 128 | 76 | 110 |
| 21Q LOSS MUTATED | 7 | 9 | 19 |
| 21Q LOSS WILD-TYPE | 121 | 67 | 91 |
Figure S427. Get High-res Image Gene #79: '21q loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.00074 (Fisher's exact test), Q value = 0.003
Table S428. Gene #79: '21q loss' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 88 | 86 | 90 | 82 | 92 | 33 |
| 21Q LOSS MUTATED | 11 | 7 | 19 | 8 | 3 | 0 |
| 21Q LOSS WILD-TYPE | 77 | 79 | 71 | 74 | 89 | 33 |
Figure S428. Get High-res Image Gene #79: '21q loss' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 6.5e-05
Table S429. Gene #79: '21q loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 135 | 112 | 85 | 139 |
| 21Q LOSS MUTATED | 4 | 12 | 21 | 11 |
| 21Q LOSS WILD-TYPE | 131 | 100 | 64 | 128 |
Figure S429. Get High-res Image Gene #79: '21q loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
P value = 0.00324 (Fisher's exact test), Q value = 0.011
Table S430. Gene #79: '21q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 111 | 221 | 193 |
| 21Q LOSS MUTATED | 20 | 13 | 20 |
| 21Q LOSS WILD-TYPE | 91 | 208 | 173 |
Figure S430. Get High-res Image Gene #79: '21q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 1e-04 (Fisher's exact test), Q value = 0.00051
Table S431. Gene #79: '21q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 117 | 33 | 183 | 132 | 35 | 25 |
| 21Q LOSS MUTATED | 10 | 4 | 10 | 17 | 2 | 10 |
| 21Q LOSS WILD-TYPE | 107 | 29 | 173 | 115 | 33 | 15 |
Figure S431. Get High-res Image Gene #79: '21q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00694 (Fisher's exact test), Q value = 0.021
Table S432. Gene #79: '21q loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 124 | 204 | 182 |
| 21Q LOSS MUTATED | 10 | 14 | 30 |
| 21Q LOSS WILD-TYPE | 114 | 190 | 152 |
Figure S432. Get High-res Image Gene #79: '21q loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.0093 (Fisher's exact test), Q value = 0.028
Table S433. Gene #79: '21q loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 144 | 134 | 195 | 37 |
| 21Q LOSS MUTATED | 14 | 24 | 12 | 4 |
| 21Q LOSS WILD-TYPE | 130 | 110 | 183 | 33 |
Figure S433. Get High-res Image Gene #79: '21q loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00982 (Fisher's exact test), Q value = 0.029
Table S434. Gene #80: '22q loss' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 33 | 24 | 13 |
| 22Q LOSS MUTATED | 0 | 5 | 2 |
| 22Q LOSS WILD-TYPE | 33 | 19 | 11 |
Figure S434. Get High-res Image Gene #80: '22q loss' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 0.00138 (Fisher's exact test), Q value = 0.0052
Table S435. Gene #80: '22q loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 11 | 12 | 4 | 11 | 13 | 9 | 10 |
| 22Q LOSS MUTATED | 0 | 0 | 2 | 4 | 0 | 0 | 1 |
| 22Q LOSS WILD-TYPE | 11 | 12 | 2 | 7 | 13 | 9 | 9 |
Figure S435. Get High-res Image Gene #80: '22q loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 6.5e-05
Table S436. Gene #80: '22q loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 238 | 135 | 155 |
| 22Q LOSS MUTATED | 2 | 13 | 24 |
| 22Q LOSS WILD-TYPE | 236 | 122 | 131 |
Figure S436. Get High-res Image Gene #80: '22q loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.00354 (Fisher's exact test), Q value = 0.012
Table S437. Gene #80: '22q loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 128 | 76 | 110 |
| 22Q LOSS MUTATED | 3 | 6 | 15 |
| 22Q LOSS WILD-TYPE | 125 | 70 | 95 |
Figure S437. Get High-res Image Gene #80: '22q loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.00037 (Fisher's exact test), Q value = 0.0016
Table S438. Gene #80: '22q loss' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 88 | 86 | 90 | 82 | 92 | 33 |
| 22Q LOSS MUTATED | 6 | 4 | 19 | 3 | 4 | 1 |
| 22Q LOSS WILD-TYPE | 82 | 82 | 71 | 79 | 88 | 32 |
Figure S438. Get High-res Image Gene #80: '22q loss' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 0.0204 (Fisher's exact test), Q value = 0.052
Table S439. Gene #80: '22q loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 135 | 112 | 85 | 139 |
| 22Q LOSS MUTATED | 5 | 15 | 9 | 8 |
| 22Q LOSS WILD-TYPE | 130 | 97 | 76 | 131 |
Figure S439. Get High-res Image Gene #80: '22q loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 6.5e-05
Table S440. Gene #80: '22q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 111 | 221 | 193 |
| 22Q LOSS MUTATED | 4 | 5 | 30 |
| 22Q LOSS WILD-TYPE | 107 | 216 | 163 |
Figure S440. Get High-res Image Gene #80: '22q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 2e-05 (Fisher's exact test), Q value = 0.00012
Table S441. Gene #80: '22q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 117 | 33 | 183 | 132 | 35 | 25 |
| 22Q LOSS MUTATED | 6 | 6 | 3 | 21 | 3 | 0 |
| 22Q LOSS WILD-TYPE | 111 | 27 | 180 | 111 | 32 | 25 |
Figure S441. Get High-res Image Gene #80: '22q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 6.5e-05
Table S442. Gene #80: '22q loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 124 | 204 | 182 |
| 22Q LOSS MUTATED | 2 | 7 | 30 |
| 22Q LOSS WILD-TYPE | 122 | 197 | 152 |
Figure S442. Get High-res Image Gene #80: '22q loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.00341 (Fisher's exact test), Q value = 0.012
Table S443. Gene #80: '22q loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 144 | 134 | 195 | 37 |
| 22Q LOSS MUTATED | 10 | 15 | 7 | 7 |
| 22Q LOSS WILD-TYPE | 134 | 119 | 188 | 30 |
Figure S443. Get High-res Image Gene #80: '22q loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0254 (Fisher's exact test), Q value = 0.062
Table S444. Gene #80: '22q loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 38 | 21 | 48 | 35 |
| 22Q LOSS MUTATED | 0 | 0 | 2 | 5 |
| 22Q LOSS WILD-TYPE | 38 | 21 | 46 | 30 |
Figure S444. Get High-res Image Gene #80: '22q loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 0.0433 (Fisher's exact test), Q value = 0.096
Table S445. Gene #81: 'xp loss' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 33 | 24 | 13 |
| XP LOSS MUTATED | 3 | 2 | 5 |
| XP LOSS WILD-TYPE | 30 | 22 | 8 |
Figure S445. Get High-res Image Gene #81: 'xp loss' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 0.00013 (Fisher's exact test), Q value = 0.00065
Table S446. Gene #81: 'xp loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 238 | 135 | 155 |
| XP LOSS MUTATED | 10 | 10 | 26 |
| XP LOSS WILD-TYPE | 228 | 125 | 129 |
Figure S446. Get High-res Image Gene #81: 'xp loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.0123 (Fisher's exact test), Q value = 0.035
Table S447. Gene #81: 'xp loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 117 | 33 | 183 | 132 | 35 | 25 |
| XP LOSS MUTATED | 9 | 1 | 12 | 11 | 6 | 7 |
| XP LOSS WILD-TYPE | 108 | 32 | 171 | 121 | 29 | 18 |
Figure S447. Get High-res Image Gene #81: 'xp loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0398 (Fisher's exact test), Q value = 0.09
Table S448. Gene #81: 'xp loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 124 | 204 | 182 |
| XP LOSS MUTATED | 7 | 14 | 24 |
| XP LOSS WILD-TYPE | 117 | 190 | 158 |
Figure S448. Get High-res Image Gene #81: 'xp loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.00094 (Fisher's exact test), Q value = 0.0036
Table S449. Gene #81: 'xp loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 144 | 134 | 195 | 37 |
| XP LOSS MUTATED | 6 | 23 | 12 | 4 |
| XP LOSS WILD-TYPE | 138 | 111 | 183 | 33 |
Figure S449. Get High-res Image Gene #81: 'xp loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0241 (Fisher's exact test), Q value = 0.06
Table S450. Gene #82: 'xq loss' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 33 | 24 | 13 |
| XQ LOSS MUTATED | 2 | 4 | 5 |
| XQ LOSS WILD-TYPE | 31 | 20 | 8 |
Figure S450. Get High-res Image Gene #82: 'xq loss' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 6.5e-05
Table S451. Gene #82: 'xq loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 238 | 135 | 155 |
| XQ LOSS MUTATED | 7 | 9 | 30 |
| XQ LOSS WILD-TYPE | 231 | 126 | 125 |
Figure S451. Get High-res Image Gene #82: 'xq loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.00897 (Fisher's exact test), Q value = 0.027
Table S452. Gene #82: 'xq loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 128 | 76 | 110 |
| XQ LOSS MUTATED | 6 | 3 | 16 |
| XQ LOSS WILD-TYPE | 122 | 73 | 94 |
Figure S452. Get High-res Image Gene #82: 'xq loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.0281 (Fisher's exact test), Q value = 0.067
Table S453. Gene #82: 'xq loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 117 | 33 | 183 | 132 | 35 | 25 |
| XQ LOSS MUTATED | 8 | 2 | 10 | 15 | 5 | 6 |
| XQ LOSS WILD-TYPE | 109 | 31 | 173 | 117 | 30 | 19 |
Figure S453. Get High-res Image Gene #82: 'xq loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.018 (Fisher's exact test), Q value = 0.047
Table S454. Gene #82: 'xq loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 124 | 204 | 182 |
| XQ LOSS MUTATED | 8 | 12 | 25 |
| XQ LOSS WILD-TYPE | 116 | 192 | 157 |
Figure S454. Get High-res Image Gene #82: 'xq loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.00334 (Fisher's exact test), Q value = 0.011
Table S455. Gene #82: 'xq loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 144 | 134 | 195 | 37 |
| XQ LOSS MUTATED | 9 | 22 | 10 | 4 |
| XQ LOSS WILD-TYPE | 135 | 112 | 185 | 33 |
Figure S455. Get High-res Image Gene #82: 'xq loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
-
Copy number data file = broad_values_by_arm.txt from GISTIC pipeline
-
Processed Copy number data file = /xchip/cga/gdac-prod/tcga-gdac/jobResults/GDAC_Correlate_Genomic_Events_Preprocess/KIRC-TP/20146401/transformed.cor.cli.txt
-
Molecular subtypes file = /xchip/cga/gdac-prod/tcga-gdac/jobResults/GDAC_mergedClustering/KIRC-TP/20125734/KIRC-TP.transferedmergedcluster.txt
-
Number of patients = 528
-
Number of significantly arm-level cnvs = 82
-
Number of molecular subtypes = 12
-
Exclude genes that fewer than K tumors have mutations, K = 3
For binary or multi-class clinical features (nominal or ordinal), two-tailed Fisher's exact tests (Fisher 1922) were used to estimate the P values using the 'fisher.test' function in R
For multiple hypothesis correction, Q value is the False Discovery Rate (FDR) analogue of the P value (Benjamini and Hochberg 1995), defined as the minimum FDR at which the test may be called significant. We used the 'Benjamini and Hochberg' method of 'p.adjust' function in R to convert P values into Q values.