		Clinical Features	CN_CNMF		METHLYATION_CNMF		RPPA_CNMF		RPPA_CHIERARCHICAL		MRNASEQ_CNMF		MRNASEQ_CHIERARCHICAL		MIRSEQ_CNMF		MIRSEQ_CHIERARCHICAL		MIRSEQ_MATURE_CNMF		MIRSEQ_MATURE_CHIERARCHICAL	
	nCNV (%)	nWild-Type	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q
1p gain	87 (24%)	279	0.13223	0.401	0.12217	0.39	0.84292	0.956	0.97757	0.996	0.87268	0.964	0.3511	0.65	0.17138	0.464	0.94474	0.978	0.75776	0.916	0.35863	0.65
1q gain	171 (47%)	195	9.9999e-06	0.000631	0.66483	0.865	0.50076	0.752	0.50809	0.758	0.03315	0.181	0.33156	0.637	0.02303	0.14	0.053499	0.238	0.04074	0.206	0.18177	0.478
2p gain	67 (18%)	299	0.01106	0.0856	0.25842	0.559	0.41312	0.694	0.81697	0.95	0.0042	0.0463	0.0081399	0.0703	0.12228	0.39	0.00043	0.00925	0.054609	0.239	0.00155	0.0235
2q gain	65 (18%)	301	0.0081199	0.0703	0.44798	0.716	0.63766	0.854	0.34432	0.647	0.00044	0.00925	0.0121	0.0894	0.10172	0.343	0.00017	0.00516	0.070599	0.278	2e-04	0.00566
3p gain	63 (17%)	303	0.21966	0.515	0.2485	0.546	0.13068	0.401	0.02076	0.131	0.41692	0.696	0.32822	0.637	0.66599	0.865	0.33449	0.637	0.52311	0.766	0.92178	0.978
3q gain	72 (20%)	294	0.56114	0.791	0.46342	0.728	0.071129	0.278	0.04685	0.224	0.04576	0.223	0.23865	0.535	0.38498	0.675	0.57367	0.806	0.10689	0.354	0.79552	0.939
4p gain	56 (15%)	310	0.00193	0.0274	0.19163	0.486	0.19323	0.487	0.85904	0.963	0.31935	0.631	0.24569	0.544	0.64212	0.855	0.00241	0.0318	0.81672	0.95	0.54127	0.777
4q gain	47 (13%)	319	0.01174	0.0883	0.32353	0.634	0.25084	0.55	0.93407	0.978	0.21444	0.511	0.38956	0.677	0.7296	0.901	0.0038	0.0437	0.9186	0.978	0.86643	0.964
5p gain	76 (21%)	290	0.00048	0.00984	0.17144	0.464	0.71879	0.894	0.39455	0.681	0.22397	0.517	0.57996	0.81	0.1094	0.359	0.46773	0.731	1	1	0.13038	0.401
5q gain	52 (14%)	314	0.01041	0.0837	0.14059	0.415	0.25209	0.55	0.13912	0.415	0.9818	0.996	0.77721	0.924	0.30389	0.614	0.62626	0.85	0.42991	0.705	0.02017	0.129
6p gain	144 (39%)	222	0.00038	0.00911	7.9999e-05	0.00345	0.95523	0.983	0.14373	0.419	0.32502	0.635	0.0236	0.141	0.098669	0.34	0.00012	0.00428	0.00094999	0.0169	5e-04	0.01
6q gain	48 (13%)	318	0.30961	0.618	0.582	0.812	0.92394	0.978	0.33098	0.637	0.94241	0.978	0.68898	0.88	0.67831	0.875	0.20654	0.501	0.93406	0.978	0.70958	0.892
7p gain	203 (55%)	163	9.9999e-06	0.000631	0.93624	0.978	0.49439	0.752	0.37072	0.662	0.01885	0.122	0.19897	0.493	0.77463	0.923	0.71066	0.892	0.077259	0.289	0.30743	0.616
7q gain	200 (55%)	166	3e-05	0.00145	0.91036	0.978	0.71728	0.894	0.5169	0.762	0.0065299	0.0608	0.18911	0.483	0.83652	0.956	0.37399	0.662	0.00292	0.0357	0.29424	0.602
8p gain	121 (33%)	245	9.9999e-06	0.000631	0.17379	0.469	0.87926	0.967	0.84192	0.956	0.01265	0.0926	0.03585	0.186	0.60599	0.834	0.93706	0.978	0.95457	0.983	0.651	0.862
8q gain	169 (46%)	197	9.9999e-06	0.000631	0.00105	0.0179	0.69752	0.887	0.79674	0.939	0.00435	0.0463	0.11082	0.362	0.81785	0.95	0.34846	0.65	0.93395	0.978	0.69969	0.887
9p gain	16 (4%)	350	0.30544	0.614	0.2045	0.499	0.23175	0.529	0.83972	0.956	0.342	0.646	0.91256	0.978	0.89076	0.974	0.72661	0.901	0.10031	0.34	0.46021	0.727
9q gain	21 (6%)	345	0.66328	0.865	0.65768	0.864	0.14011	0.415	0.92797	0.978	0.56121	0.791	0.49291	0.752	0.73552	0.905	0.68524	0.879	0.50287	0.752	0.64346	0.855
10p gain	12 (3%)	354	0.49586	0.752	0.93143	0.978	0.93542	0.978	0.54621	0.779	0.71169	0.892	1	1	0.19901	0.493	0.3375	0.639	0.92763	0.978	0.96578	0.99
10q gain	3 (1%)	363	0.37647	0.662	0.3582	0.65	NA	NA	NA	NA	0.63594	0.854	0.63771	0.854	0.796	0.939	0.84854	0.958	0.27509	0.578	0.70177	0.887
11p gain	35 (10%)	331	0.0068699	0.0633	0.094459	0.33	0.13366	0.402	0.18628	0.482	0.00122	0.0196	0.0075099	0.0676	0.02096	0.131	0.00435	0.0463	0.29686	0.604	0.02283	0.14
11q gain	29 (8%)	337	0.00031	0.00794	0.18766	0.482	0.14525	0.422	0.086809	0.312	0.00282	0.035	0.0012	0.0196	0.0056699	0.0574	0.00015	0.00492	0.079639	0.293	0.02023	0.129
12p gain	65 (18%)	301	0.00084999	0.0157	0.16366	0.456	0.63832	0.854	0.42409	0.699	0.01278	0.0927	0.86096	0.963	0.62246	0.848	0.39166	0.678	0.23671	0.532	0.42164	0.699
12q gain	39 (11%)	327	0.01633	0.11	1	1	0.60569	0.834	0.057939	0.245	0.54164	0.777	0.64289	0.855	0.87198	0.964	0.16303	0.456	0.42391	0.699	0.056399	0.243
13q gain	94 (26%)	272	9.9999e-06	0.000631	9.9999e-06	0.000631	0.3897	0.677	0.31317	0.621	0.00044	0.00925	0.0062199	0.0608	0.37318	0.662	0.89464	0.976	0.12462	0.393	0.74276	0.906
14q gain	41 (11%)	325	0.39562	0.681	0.40018	0.684	0.49889	0.752	0.15348	0.442	0.83432	0.956	0.91504	0.978	0.65948	0.864	0.84648	0.957	0.76712	0.92	0.9816	0.996
15q gain	85 (23%)	281	2e-05	0.00109	0.19686	0.492	0.97518	0.995	0.8161	0.95	0.00347	0.0406	0.01697	0.113	0.13126	0.401	0.14236	0.418	0.27846	0.58	0.04453	0.22
16p gain	58 (16%)	308	0.00189	0.0274	0.03414	0.182	0.83853	0.956	0.65959	0.864	4e-04	0.00911	0.12539	0.393	0.44401	0.713	0.10613	0.354	0.43756	0.712	0.41104	0.692
16q gain	44 (12%)	322	2e-04	0.00566	0.053859	0.238	0.22288	0.517	0.62789	0.85	3e-05	0.00145	0.03263	0.181	0.44945	0.716	0.12543	0.393	0.44456	0.713	0.23455	0.53
17p gain	37 (10%)	329	0.0098199	0.0803	0.00098999	0.0173	0.74194	0.906	0.52837	0.766	0.078669	0.293	0.51465	0.762	0.49696	0.752	0.40058	0.684	0.92589	0.978	0.31213	0.621
17q gain	65 (18%)	301	0.051159	0.233	0.04843	0.226	0.35097	0.65	0.27644	0.58	0.98491	0.997	0.33351	0.637	0.38932	0.677	0.4417	0.713	0.36015	0.65	0.64925	0.861
18p gain	55 (15%)	311	0.00213	0.0291	0.606	0.834	0.17993	0.478	0.39062	0.677	0.2618	0.565	0.65926	0.864	0.76672	0.92	0.82738	0.955	0.070149	0.278	0.89835	0.978
18q gain	44 (12%)	322	0.00077999	0.0149	0.67716	0.874	0.29356	0.602	0.46981	0.731	0.21702	0.514	0.82955	0.955	0.49727	0.752	0.86021	0.963	0.66026	0.864	0.71438	0.894
19p gain	57 (16%)	309	0.0053299	0.0553	0.02315	0.14	0.589	0.818	0.79733	0.939	0.00138	0.0214	0.2419	0.538	0.92044	0.978	0.36063	0.65	0.19997	0.493	0.76359	0.919
19q gain	56 (15%)	310	0.01091	0.0856	0.01859	0.121	0.58946	0.818	1	1	5e-05	0.00228	0.063509	0.26	0.6931	0.884	0.33561	0.637	0.27342	0.576	0.88424	0.971
20p gain	147 (40%)	219	9.9999e-06	0.000631	0.0094399	0.0798	0.83473	0.956	0.98435	0.997	0.00015	0.00492	0.02145	0.133	0.70172	0.887	0.24605	0.544	0.28906	0.599	0.17882	0.478
20q gain	179 (49%)	187	9.9999e-06	0.000631	0.01599	0.109	0.88777	0.973	0.97398	0.995	0.00388	0.0437	0.16125	0.455	0.72343	0.899	0.19065	0.486	0.90407	0.978	0.46841	0.731
21q gain	67 (18%)	299	0.16521	0.458	0.04849	0.226	0.86303	0.963	0.5284	0.766	0.1932	0.487	0.35663	0.65	0.16577	0.458	0.79912	0.94	0.90276	0.978	0.75878	0.916
22q gain	126 (34%)	240	0.00035	0.0087	0.11891	0.384	0.66755	0.866	0.94392	0.978	0.073139	0.28	0.25314	0.551	0.48588	0.75	0.21651	0.514	0.82965	0.955	0.54238	0.777
xp gain	41 (11%)	325	9.9999e-05	0.0041	0.00194	0.0274	0.90251	0.978	0.22705	0.52	0.0076099	0.0676	0.2211	0.517	0.2179	0.515	0.73374	0.905	0.00059999	0.0117	0.70632	0.891
xq gain	43 (12%)	323	0.00011	0.0041	0.00022	0.00582	0.32855	0.637	0.98637	0.997	0.00426	0.0463	0.18892	0.483	0.22382	0.517	0.63506	0.854	0.00021	0.00574	0.42449	0.699
1p loss	53 (14%)	313	0.04809	0.226	0.00039	0.00911	0.65364	0.864	0.31364	0.621	0.0106	0.0844	0.13183	0.401	0.04946	0.228	0.94884	0.981	0.12731	0.396	0.088669	0.315
1q loss	28 (8%)	338	0.064519	0.262	0.055529	0.242	0.96972	0.991	0.46317	0.728	0.11663	0.38	0.35449	0.65	0.50096	0.752	0.68728	0.879	0.27862	0.58	0.68246	0.877
2p loss	51 (14%)	315	0.37592	0.662	0.21147	0.509	0.0095799	0.0802	0.01467	0.102	0.92791	0.978	0.03426	0.182	0.0053099	0.0553	0.01825	0.12	0.18493	0.482	0.29265	0.602
2q loss	52 (14%)	314	0.81392	0.95	0.19373	0.487	0.00305	0.0367	0.00164	0.0245	0.76049	0.917	0.21279	0.51	0.0064099	0.0608	0.02907	0.169	0.12387	0.392	0.43409	0.71
3p loss	61 (17%)	305	0.061389	0.253	0.82111	0.952	0.36236	0.65	0.32707	0.637	0.10707	0.354	0.15518	0.443	0.03883	0.199	0.61623	0.845	0.45145	0.716	0.51669	0.762
3q loss	53 (14%)	313	0.0464	0.224	0.090359	0.319	0.40943	0.691	0.37441	0.662	0.37468	0.662	0.2513	0.55	0.067259	0.272	0.26401	0.567	0.28864	0.599	0.86847	0.964
4p loss	80 (22%)	286	0.5288	0.766	0.19938	0.493	0.36027	0.65	0.96973	0.991	0.16148	0.455	0.063739	0.26	0.73643	0.905	0.0060399	0.0604	0.91607	0.978	0.087759	0.313
4q loss	85 (23%)	281	0.52681	0.766	0.071419	0.278	0.44168	0.713	0.7505	0.912	0.21861	0.515	0.03425	0.182	0.9429	0.978	0.0027	0.0346	0.53466	0.773	0.01428	0.1
5p loss	79 (22%)	287	0.85207	0.961	0.16259	0.456	0.94061	0.978	0.86197	0.963	0.83932	0.956	0.077149	0.289	0.67214	0.869	0.30113	0.611	0.34493	0.647	0.52536	0.766
5q loss	99 (27%)	267	0.58844	0.818	0.057449	0.245	0.44256	0.713	0.3591	0.65	0.86136	0.963	0.04996	0.229	0.95092	0.982	0.74781	0.91	0.8276	0.955	0.77313	0.923
6p loss	68 (19%)	298	0.0055499	0.0569	0.46564	0.73	0.92496	0.978	0.27751	0.58	0.01318	0.0948	0.03539	0.186	0.16984	0.464	0.072609	0.28	0.074019	0.282	0.0064499	0.0608
6q loss	172 (47%)	194	9.9999e-06	0.000631	0.01407	0.0995	0.91185	0.978	0.481	0.746	0.00244	0.0318	0.084269	0.307	0.43481	0.71	0.23687	0.532	0.41556	0.696	0.27016	0.572
7p loss	18 (5%)	348	0.82906	0.955	0.052009	0.233	0.04911	0.228	0.55667	0.789	0.42292	0.699	0.84276	0.956	0.50314	0.752	0.76891	0.92	0.12987	0.401	0.78487	0.931
7q loss	17 (5%)	349	0.36338	0.651	0.0097699	0.0803	0.18751	0.482	0.43992	0.713	0.40215	0.686	0.41987	0.698	0.78654	0.932	0.83284	0.956	0.070109	0.278	0.97908	0.996
8p loss	67 (18%)	299	0.12232	0.39	0.45032	0.716	0.086279	0.312	0.29438	0.602	0.057619	0.245	0.52151	0.765	0.2484	0.546	0.04678	0.224	0.93842	0.978	0.18183	0.478
8q loss	27 (7%)	339	0.51854	0.763	0.0074199	0.0676	0.1751	0.471	0.53516	0.773	0.23289	0.53	0.74032	0.906	0.33116	0.637	0.66848	0.866	0.071509	0.278	0.13243	0.401
9p loss	236 (64%)	130	0.00017	0.00516	0.13389	0.402	0.35569	0.65	0.44884	0.716	0.00309	0.0367	0.099479	0.34	0.0303	0.175	0.069249	0.278	0.57646	0.807	0.68671	0.879
9q loss	185 (51%)	181	0.27183	0.574	0.070079	0.278	0.98861	0.998	0.14928	0.433	0.01129	0.0862	0.33567	0.637	0.01559	0.107	0.059879	0.249	0.67956	0.875	0.69703	0.887
10p loss	204 (56%)	162	9.9999e-06	0.000631	0.12736	0.396	0.8012	0.941	0.40897	0.691	0.00136	0.0214	0.01631	0.11	0.20002	0.493	0.20776	0.502	0.50074	0.752	0.75264	0.913
10q loss	224 (61%)	142	9.9999e-06	0.000631	0.20811	0.502	0.92556	0.978	0.20154	0.495	0.00011	0.0041	0.00227	0.0305	0.03224	0.181	0.21431	0.511	0.43016	0.705	0.63015	0.851
11p loss	126 (34%)	240	0.01754	0.116	0.056189	0.243	0.34373	0.647	0.29189	0.602	0.46941	0.731	0.099069	0.34	0.22712	0.52	0.12277	0.39	0.094949	0.33	0.23416	0.53
11q loss	148 (40%)	218	0.01192	0.0889	0.35004	0.65	0.86566	0.964	0.69865	0.887	0.22339	0.517	0.00211	0.0291	0.35835	0.65	0.23403	0.53	0.10645	0.354	0.04438	0.22
12p loss	59 (16%)	307	0.2192	0.515	0.10802	0.356	0.70801	0.892	0.87155	0.964	0.01408	0.0995	0.89113	0.974	0.33499	0.637	0.18695	0.482	0.89523	0.976	0.83016	0.955
12q loss	67 (18%)	299	0.03468	0.183	0.0076699	0.0676	0.81789	0.95	0.87509	0.964	0.051999	0.233	0.55643	0.789	0.3619	0.65	0.40883	0.691	0.61823	0.846	0.87414	0.964
13q loss	80 (22%)	286	0.93561	0.978	0.01096	0.0856	0.04721	0.224	0.55775	0.789	0.6605	0.864	0.03302	0.181	0.59999	0.831	0.33463	0.637	0.15756	0.447	0.63368	0.854
14q loss	112 (31%)	254	2e-05	0.00109	0.32028	0.631	0.17107	0.464	0.26954	0.572	0.0090999	0.0777	0.03332	0.181	0.35849	0.65	0.8134	0.95	0.40794	0.691	0.10595	0.354
15q loss	52 (14%)	314	0.18403	0.482	0.35547	0.65	0.26336	0.567	0.060939	0.252	0.80214	0.941	0.26668	0.571	0.71672	0.894	0.57416	0.806	0.60743	0.834	0.50225	0.752
16p loss	68 (19%)	298	0.20521	0.499	0.094639	0.33	0.0441	0.22	0.35964	0.65	0.059429	0.249	0.1549	0.443	0.18103	0.478	0.16481	0.458	0.087149	0.312	0.3594	0.65
16q loss	106 (29%)	260	0.302	0.611	0.3241	0.634	0.02732	0.16	0.75375	0.913	0.03811	0.197	0.03593	0.186	0.24168	0.538	0.16968	0.464	0.04515	0.222	0.11844	0.384
17p loss	127 (35%)	239	0.076519	0.289	0.0062399	0.0608	0.32313	0.634	0.51534	0.762	0.18703	0.482	0.053879	0.238	0.76709	0.92	0.54823	0.78	0.71645	0.894	0.52149	0.765
17q loss	64 (17%)	302	0.1435	0.419	0.13425	0.402	0.18043	0.478	0.54403	0.777	0.92427	0.978	0.49551	0.752	0.86817	0.964	0.5369	0.774	0.03202	0.181	0.91926	0.978
18p loss	104 (28%)	262	0.72973	0.901	0.60063	0.831	0.57575	0.807	0.5135	0.762	0.02641	0.156	0.16691	0.459	0.29686	0.604	0.079259	0.293	0.4546	0.72	0.46261	0.728
18q loss	100 (27%)	266	0.44802	0.716	0.87971	0.967	0.20526	0.499	0.49032	0.752	0.44462	0.713	0.43731	0.712	0.62135	0.848	0.098549	0.34	0.41681	0.696	0.48827	0.752
19p loss	77 (21%)	289	0.072959	0.28	0.65796	0.864	0.55746	0.789	0.03311	0.181	0.15013	0.433	0.25392	0.551	0.4981	0.752	0.93215	0.978	0.51188	0.762	0.52468	0.766
19q loss	73 (20%)	293	0.02427	0.144	0.04715	0.224	0.8437	0.956	0.082959	0.304	0.091269	0.321	0.49253	0.752	0.26999	0.572	0.95655	0.983	0.057519	0.245	0.64041	0.855
20p loss	26 (7%)	340	0.37158	0.662	0.6201	0.847	0.30534	0.614	0.77228	0.923	0.19642	0.492	0.02157	0.133	0.059549	0.249	0.01135	0.0862	0.85797	0.963	0.37708	0.662
20q loss	9 (2%)	357	0.3959	0.681	0.17878	0.478	NA	NA	NA	NA	0.074229	0.282	0.0098899	0.0803	0.7373	0.905	0.38713	0.677	0.26834	0.572	0.66419	0.865
21q loss	70 (19%)	296	0.099989	0.34	0.47384	0.736	0.30873	0.617	0.93097	0.978	0.92948	0.978	0.49735	0.752	0.54369	0.777	0.74097	0.906	0.7776	0.924	0.39902	0.684
22q loss	39 (11%)	327	0.40316	0.686	0.41739	0.696	0.95337	0.983	0.93986	0.978	0.2406	0.538	0.96297	0.988	0.62751	0.85	0.74551	0.908	0.72793	0.901	0.90048	0.978
xp loss	97 (27%)	269	0.03054	0.175	9.9999e-06	0.000631	0.04459	0.22	0.22653	0.52	0.00109	0.0182	0.00389	0.0437	0.00274	0.0346	0.1407	0.415	0.084509	0.307	0.85448	0.962
xq loss	93 (25%)	273	0.03927	0.2	9.9999e-06	0.000631	0.15548	0.443	0.078909	0.293	0.00085999	0.0157	0.0064799	0.0608	0.03297	0.181	0.48529	0.75	0.051329	0.233	0.62751	0.85
