		Clinical Features	CN_CNMF		METHLYATION_CNMF		RPPA_CNMF		RPPA_CHIERARCHICAL		MRNASEQ_CNMF		MRNASEQ_CHIERARCHICAL		MIRSEQ_CNMF		MIRSEQ_CHIERARCHICAL		MIRSEQ_MATURE_CNMF		MIRSEQ_MATURE_CHIERARCHICAL	
	nCNV (%)	nWild-Type	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q
1p gain	24 (43%)	32	0.20051	0.744	0.75367	0.979	0.73685	0.979	0.69258	0.979	0.82005	1	0.90233	1	0.52728	0.944	0.28356	0.781	0.60563	0.952	0.56671	0.952
1q gain	31 (55%)	25	0.4375	0.907	0.76733	0.984	0.93541	1	0.59385	0.952	0.76167	0.979	0.61839	0.959	0.70672	0.979	0.45634	0.921	0.88321	1	0.81486	1
2p gain	23 (41%)	33	0.88659	1	0.0078199	0.375	0.10937	0.705	0.03477	0.584	0.01928	0.479	0.056099	0.616	0.49538	0.938	0.072209	0.663	0.10102	0.705	0.13517	0.716
2q gain	21 (38%)	35	0.37327	0.858	0.01848	0.479	0.13501	0.716	0.3133	0.798	0.01203	0.432	0.11184	0.705	0.6224	0.959	0.0488	0.595	0.19502	0.744	0.11201	0.705
3p gain	12 (21%)	44	0.21204	0.744	0.259	0.781	0.10422	0.705	0.2103	0.744	0.43141	0.901	0.19961	0.744	0.86073	1	0.26476	0.781	0.4508	0.919	0.55395	0.952
3q gain	23 (41%)	33	0.10059	0.705	0.04861	0.595	0.33697	0.824	0.56555	0.952	0.1958	0.744	0.12034	0.705	0.49712	0.938	0.19017	0.744	0.073849	0.663	0.22101	0.747
4p gain	9 (16%)	47	0.72953	0.979	0.70118	0.979	0.03209	0.552	0.02631	0.524	0.82271	1	0.86672	1	0.77485	0.984	0.3253	0.809	0.26066	0.781	0.36819	0.853
4q gain	3 (5%)	53	1	1	0.2556	0.781	NA	NA	NA	NA	0.51389	0.944	0.79251	0.995	0.67455	0.979	0.56476	0.952	0.59808	0.952	0.69534	0.979
5p gain	23 (41%)	33	0.04465	0.595	0.37532	0.858	0.0060499	0.355	0.19883	0.744	0.45117	0.919	0.24292	0.768	0.74335	0.979	0.0288	0.542	0.59625	0.952	0.15161	0.734
5q gain	8 (14%)	48	0.51116	0.944	0.56456	0.952	0.02243	0.479	0.20921	0.744	0.31117	0.797	0.2473	0.769	0.080509	0.664	0.15447	0.734	0.1298	0.716	0.19234	0.744
6p gain	30 (54%)	26	0.19494	0.744	0.52304	0.944	0.5524	0.952	0.52135	0.944	0.60115	0.952	0.41506	0.896	1	1	0.47421	0.926	0.73709	0.979	0.32122	0.809
6q gain	27 (48%)	29	0.20823	0.744	0.20578	0.744	0.60764	0.952	0.62009	0.959	0.22416	0.747	0.16652	0.744	1	1	0.19011	0.744	0.64958	0.976	0.1397	0.716
7p gain	21 (38%)	35	0.20066	0.744	0.55654	0.952	0.9078	1	0.28994	0.781	0.1514	0.734	0.28193	0.781	0.59251	0.952	0.13169	0.716	0.32888	0.811	0.12101	0.705
7q gain	17 (30%)	39	0.58491	0.952	0.84205	1	0.69181	0.979	0.86984	1	0.33911	0.824	0.8098	0.997	0.74217	0.979	0.16719	0.744	1	1	0.1537	0.734
8p gain	19 (34%)	37	0.18763	0.744	0.74222	0.979	0.50252	0.942	0.27791	0.781	0.44483	0.919	0.87112	1	0.97003	1	0.55818	0.952	0.66451	0.979	0.59596	0.952
8q gain	30 (54%)	26	0.01441	0.474	0.19729	0.744	0.55176	0.952	0.59371	0.952	0.050539	0.595	0.50576	0.942	0.21485	0.744	0.3244	0.809	0.067459	0.65	0.12244	0.705
9p gain	6 (11%)	50	0.35145	0.839	0.70271	0.979	0.75845	0.979	0.12397	0.705	0.93553	1	0.66497	0.979	0.83187	1	0.80442	0.997	0.86132	1	1	1
10p gain	21 (38%)	35	0.32676	0.809	0.02031	0.479	0.17339	0.744	0.29951	0.781	0.03998	0.595	0.11992	0.705	0.32623	0.809	0.10639	0.705	0.67758	0.979	0.19894	0.744
10q gain	17 (30%)	39	0.87448	1	0.33718	0.824	0.23886	0.764	0.46496	0.926	0.55131	0.952	0.04807	0.595	0.22237	0.747	0.18242	0.744	0.38015	0.858	0.073409	0.663
11p gain	5 (9%)	51	0.71989	0.979	0.44663	0.919	0.20939	0.744	0.92526	1	0.26381	0.781	0.85098	1	0.49305	0.938	0.11862	0.705	0.51902	0.944	0.093339	0.696
11q gain	7 (12%)	49	0.68212	0.979	0.38757	0.862	0.0192	0.479	0.71647	0.979	0.22716	0.751	0.38175	0.859	0.75536	0.979	0.03631	0.59	0.57801	0.952	0.03106	0.552
12p gain	22 (39%)	34	0.2622	0.781	0.00431	0.355	0.31437	0.799	0.59428	0.952	0.37462	0.858	0.04268	0.595	0.80971	0.997	0.97716	1	0.52917	0.944	0.62913	0.961
12q gain	11 (20%)	45	0.53713	0.947	0.53246	0.945	0.65169	0.977	0.85455	1	0.80508	0.997	0.52474	0.944	1	1	0.29822	0.781	0.91032	1	0.27038	0.781
13q gain	15 (27%)	41	0.64841	0.976	0.070319	0.663	0.26579	0.781	0.54436	0.949	0.0215	0.479	0.02432	0.506	0.2223	0.747	0.04599	0.595	0.01013	0.405	0.14186	0.718
14q gain	7 (12%)	49	0.60705	0.952	0.57697	0.952	0.11324	0.705	0.04936	0.595	0.25477	0.781	0.26114	0.781	0.20594	0.744	0.73537	0.979	0.22574	0.749	0.4716	0.926
15q gain	4 (7%)	52	0.18927	0.744	0.25321	0.781	0.75913	0.979	0.57674	0.952	0.57632	0.952	0.3247	0.809	0.75584	0.979	0.34752	0.832	0.42452	0.899	0.35483	0.842
16p gain	10 (18%)	46	0.10974	0.705	0.28071	0.781	0.17972	0.744	0.82988	1	0.19696	0.744	0.27676	0.781	1	1	0.48102	0.933	0.90376	1	0.40698	0.887
16q gain	6 (11%)	50	0.17226	0.744	0.84908	1	0.74612	0.979	0.92561	1	0.54567	0.949	0.9684	1	0.77079	0.984	0.92622	1	0.475	0.926	0.86688	1
17p gain	9 (16%)	47	0.38953	0.864	0.89627	1	0.95285	1	0.82702	1	0.56907	0.952	0.5629	0.952	0.28389	0.781	0.060689	0.632	0.1286	0.716	0.1727	0.744
17q gain	18 (32%)	38	0.42141	0.896	0.27164	0.781	0.63343	0.963	0.80018	0.997	0.70182	0.979	0.51366	0.944	0.39259	0.869	0.30581	0.79	0.75949	0.979	0.4324	0.901
18p gain	18 (32%)	38	0.67597	0.979	0.04909	0.595	0.68893	0.979	0.78703	0.993	0.094349	0.697	0.3448	0.832	0.14558	0.728	0.19881	0.744	0.40775	0.887	0.431	0.901
18q gain	14 (25%)	42	0.68528	0.979	0.080859	0.664	0.59653	0.952	0.59024	0.952	0.15399	0.734	0.23996	0.764	0.20406	0.744	0.084769	0.676	0.1388	0.716	0.16915	0.744
19p gain	24 (43%)	32	0.11512	0.705	0.17741	0.744	0.33886	0.824	0.72414	0.979	0.27016	0.781	0.36431	0.846	0.53484	0.945	0.22938	0.751	0.41999	0.896	0.51019	0.944
19q gain	28 (50%)	28	0.12452	0.705	0.075569	0.664	0.73339	0.979	0.8737	1	0.37907	0.858	0.39897	0.878	0.92952	1	0.89797	1	0.88566	1	0.93759	1
20p gain	37 (66%)	19	0.28727	0.781	0.50352	0.942	0.10922	0.705	0.59536	0.952	0.92338	1	0.75864	0.979	0.87464	1	0.69603	0.979	0.22326	0.747	0.47214	0.926
20q gain	44 (79%)	12	0.051899	0.595	0.91888	1	0.21361	0.744	0.95179	1	0.96867	1	0.99646	1	0.58901	0.952	0.57622	0.952	0.21401	0.744	0.67967	0.979
21q gain	18 (32%)	38	0.073219	0.663	0.37681	0.858	0.48931	0.938	0.78578	0.993	0.9013	1	0.89202	1	0.91456	1	0.57152	0.952	1	1	0.94851	1
22q gain	8 (14%)	48	0.71129	0.979	0.96122	1	0.4536	0.919	0.3023	0.786	0.80477	0.997	0.92533	1	0.88575	1	0.94398	1	1	1	1	1
xp gain	18 (32%)	38	0.93799	1	0.01008	0.405	0.40376	0.886	0.48322	0.933	0.01945	0.479	0.24596	0.769	0.79979	0.997	0.56107	0.952	0.20319	0.744	0.43318	0.901
xq gain	15 (27%)	41	0.69603	0.979	0.36371	0.846	0.72298	0.979	0.76146	0.979	0.76206	0.979	0.71409	0.979	0.87005	1	0.29272	0.781	1	1	0.088949	0.689
1p loss	9 (16%)	47	0.59618	0.952	0.60369	0.952	0.48606	0.934	0.62603	0.959	0.92187	1	0.11798	0.705	0.11056	0.705	0.02997	0.551	0.054669	0.608	0.04924	0.595
1q loss	9 (16%)	47	0.48322	0.933	0.51844	0.944	0.73566	0.979	0.29772	0.781	0.51337	0.944	0.077839	0.664	0.42182	0.896	0.15617	0.734	0.21217	0.744	0.14553	0.728
3p loss	20 (36%)	36	0.01025	0.405	0.41971	0.896	0.40674	0.887	0.71487	0.979	0.0488	0.595	0.22997	0.751	0.37612	0.858	0.92751	1	0.4188	0.896	0.43044	0.901
3q loss	14 (25%)	42	0.13861	0.716	0.45836	0.921	0.83577	1	0.79563	0.996	0.1377	0.716	0.6023	0.952	0.52737	0.944	0.87907	1	0.3827	0.859	1	1
4p loss	31 (55%)	25	0.065889	0.65	0.062779	0.636	0.1684	0.744	0.082319	0.664	0.25718	0.781	0.20248	0.744	0.03742	0.59	0.71272	0.979	0.14775	0.73	0.44647	0.919
4q loss	33 (59%)	23	0.1883	0.744	0.01843	0.479	0.29178	0.781	0.090239	0.689	0.00495	0.355	0.03882	0.59	9.9999e-05	0.079	0.24637	0.769	0.02075	0.479	0.13537	0.716
5p loss	9 (16%)	47	0.90199	1	0.47587	0.926	0.01593	0.479	0.062369	0.636	0.88421	1	0.13498	0.716	1	1	0.29938	0.781	1	1	0.41669	0.896
5q loss	18 (32%)	38	0.77036	0.984	0.30805	0.793	0.10502	0.705	0.078009	0.664	0.26538	0.781	0.2321	0.755	0.35986	0.842	0.94658	1	0.35536	0.842	0.94812	1
6p loss	5 (9%)	51	0.42564	0.899	0.95574	1	0.46308	0.926	0.75099	0.979	0.75666	0.979	0.95545	1	0.54359	0.949	0.9102	1	1	1	1	1
6q loss	7 (12%)	49	0.064099	0.641	0.69926	0.979	0.38686	0.862	0.16469	0.744	0.63963	0.97	0.90095	1	0.70616	0.979	0.61787	0.959	0.67156	0.979	0.61552	0.959
7p loss	13 (23%)	43	1	1	0.66468	0.979	0.54517	0.949	0.28475	0.781	0.73716	0.979	0.49767	0.938	0.31186	0.797	0.45365	0.919	0.77359	0.984	0.59919	0.952
7q loss	13 (23%)	43	0.11937	0.705	0.85387	1	0.32515	0.809	0.49656	0.938	0.92019	1	0.8211	1	0.7174	0.979	0.22148	0.747	1	1	0.52875	0.944
8p loss	23 (41%)	33	0.28926	0.781	0.98202	1	0.53929	0.949	0.27359	0.781	0.82967	1	0.74506	0.979	0.68674	0.979	0.51244	0.944	0.60451	0.952	0.57684	0.952
8q loss	9 (16%)	47	1	1	0.75546	0.979	0.81131	0.997	0.68863	0.979	0.29801	0.781	0.71264	0.979	0.94834	1	0.75758	0.979	0.26048	0.781	0.66885	0.979
9p loss	34 (61%)	22	0.29768	0.781	0.0079099	0.375	0.051889	0.595	0.00047	0.186	0.67296	0.979	0.13472	0.716	0.86444	1	0.28763	0.781	1	1	0.060779	0.632
9q loss	39 (70%)	17	0.18953	0.744	0.00161	0.318	0.14053	0.716	0.02183	0.479	0.49632	0.938	0.0387	0.59	0.66372	0.979	0.11853	0.705	1	1	0.16176	0.744
10p loss	23 (41%)	33	0.62563	0.959	0.01331	0.457	0.66602	0.979	0.72128	0.979	0.02883	0.542	0.18679	0.744	0.2462	0.769	0.78992	0.994	0.88028	1	0.8958	1
10q loss	21 (38%)	35	0.8859	1	0.29772	0.781	0.27458	0.781	0.78295	0.991	0.17633	0.744	0.17025	0.744	0.12416	0.705	0.47146	0.926	0.39808	0.878	0.73766	0.979
11p loss	26 (46%)	30	1	1	0.00374	0.355	0.87997	1	0.85771	1	0.37774	0.858	0.51733	0.944	0.26892	0.781	0.57974	0.952	0.50543	0.942	0.36009	0.842
11q loss	24 (43%)	32	0.62574	0.959	0.0080699	0.375	0.71788	0.979	0.80627	0.997	0.80458	0.997	0.89157	1	0.29367	0.781	0.58966	0.952	0.21998	0.747	0.18304	0.744
12p loss	13 (23%)	43	0.30471	0.789	0.27556	0.781	0.52836	0.944	0.7403	0.979	0.57999	0.952	0.73445	0.979	0.54677	0.949	0.57826	0.952	1	1	0.21729	0.747
12q loss	14 (25%)	42	0.42732	0.9	0.88013	1	0.87346	1	0.12501	0.705	0.81986	1	0.91456	1	0.96527	1	0.90728	1	0.91996	1	0.60445	0.952
13q loss	26 (46%)	30	0.41662	0.896	0.00113	0.298	0.84727	1	0.14772	0.73	0.058559	0.627	0.02651	0.524	0.35722	0.842	0.11921	0.705	0.03865	0.59	0.1966	0.744
14q loss	27 (48%)	29	0.94342	1	0.093329	0.696	0.52722	0.944	0.118	0.705	0.12115	0.705	0.12303	0.705	0.61635	0.959	0.89834	1	0.93938	1	0.93826	1
15q loss	32 (57%)	24	0.0062999	0.355	0.71273	0.979	0.77196	0.984	0.051989	0.595	0.93046	1	0.98116	1	0.93128	1	0.97775	1	1	1	0.89495	1
16p loss	32 (57%)	24	0.2416	0.767	0.4925	0.938	0.97676	1	0.089019	0.689	0.34601	0.832	0.10161	0.705	0.81064	0.997	0.91331	1	0.47004	0.926	0.89538	1
16q loss	37 (66%)	19	0.77682	0.985	0.79404	0.996	0.7389	0.979	0.12952	0.716	0.4497	0.919	0.090719	0.689	0.68319	0.979	0.92405	1	0.13996	0.716	0.85854	1
17p loss	34 (61%)	22	0.54617	0.949	0.2824	0.781	0.04389	0.595	0.27406	0.781	0.98059	1	0.75858	0.979	0.8059	0.997	0.89053	1	0.23508	0.76	0.88963	1
17q loss	17 (30%)	39	0.16383	0.744	0.35801	0.842	0.52725	0.944	0.63275	0.963	0.71579	0.979	0.38526	0.862	0.96697	1	0.21418	0.744	0.93165	1	0.27712	0.781
18p loss	18 (32%)	38	0.03215	0.552	0.01677	0.479	0.40964	0.889	0.28479	0.781	0.053849	0.608	0.089249	0.689	0.067379	0.65	0.079369	0.664	0.058709	0.627	0.04629	0.595
18q loss	20 (36%)	36	0.11688	0.705	0.072569	0.663	0.31657	0.802	0.29475	0.781	0.1841	0.744	0.11898	0.705	0.01174	0.432	0.0057699	0.355	0.0061499	0.355	0.00224	0.339
19p loss	15 (27%)	41	0.5606	0.952	0.46023	0.923	0.16275	0.744	0.47247	0.926	0.20299	0.744	0.35756	0.842	0.3463	0.832	0.71754	0.979	0.21086	0.744	0.70244	0.979
19q loss	13 (23%)	43	0.73456	0.979	0.15252	0.734	0.19539	0.744	0.81764	1	0.94417	1	0.61941	0.959	0.22935	0.751	0.87364	1	0.2372	0.762	1	1
20p loss	7 (12%)	49	0.53467	0.945	0.20765	0.744	0.00285	0.339	0.003	0.339	0.081559	0.664	0.075759	0.664	0.61729	0.959	0.69209	0.979	0.5781	0.952	0.6928	0.979
20q loss	4 (7%)	52	0.37174	0.858	0.60291	0.952	0.080429	0.664	0.1923	0.744	0.11815	0.705	0.47303	0.926	1	1	0.88539	1	0.66876	0.979	0.78875	0.994
21q loss	17 (30%)	39	0.6674	0.979	0.17896	0.744	0.73355	0.979	0.32959	0.811	0.63381	0.963	0.7443	0.979	0.68083	0.979	0.97167	1	0.93139	1	0.94292	1
22q loss	33 (59%)	23	0.17575	0.744	0.96941	1	0.25318	0.781	0.02095	0.479	0.96207	1	0.90197	1	0.70622	0.979	0.29054	0.781	0.4662	0.926	0.75929	0.979
xp loss	15 (27%)	41	0.64798	0.976	0.83891	1	0.2642	0.781	0.34454	0.832	0.92678	1	0.92792	1	0.44793	0.919	0.64959	0.976	0.50439	0.942	0.76098	0.979
xq loss	18 (32%)	38	0.76962	0.984	0.15539	0.734	0.48454	0.934	0.2192	0.747	0.23574	0.76	0.62608	0.959	0.4568	0.921	0.64816	0.976	0.53221	0.945	0.70815	0.979
