		Clinical Features	CN_CNMF		METHLYATION_CNMF		MRNASEQ_CNMF		MRNASEQ_CHIERARCHICAL		MIRSEQ_CNMF		MIRSEQ_CHIERARCHICAL		MIRSEQ_MATURE_CNMF		MIRSEQ_MATURE_CHIERARCHICAL	
	nCNV (%)	nWild-Type	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q
1q gain	8 (10%)	72	0.71487	0.926	0.71441	0.926	0.70128	0.922	0.80241	0.933	0.21076	0.502	0.057539	0.245	1	1	0.03778	0.188
2p gain	10 (12%)	70	0.31704	0.593	1	1	0.03772	0.188	0.11447	0.374	0.10837	0.366	0.85013	0.958	0.55267	0.814	0.03127	0.173
2q gain	8 (10%)	72	0.39407	0.664	0.71463	0.926	0.054889	0.24	0.11223	0.369	0.27829	0.543	0.195	0.476	0.34583	0.619	0.0069999	0.056
4p gain	7 (9%)	73	0.0278	0.164	0.2817	0.543	0.1543	0.431	0.12132	0.384	0.88397	0.985	0.36781	0.639	0.8731	0.976	0.2297	0.504
4q gain	4 (5%)	76	0.15744	0.431	0.26706	0.543	0.3971	0.667	0.34469	0.619	0.42499	0.695	0.82449	0.948	1	1	0.22645	0.504
5p gain	3 (4%)	77	0.16095	0.431	0.44117	0.695	0.7844	0.933	0.10684	0.366	0.79261	0.933	0.27874	0.543	1	1	0.21579	0.502
5q gain	3 (4%)	77	0.15964	0.431	0.43917	0.695	0.78406	0.933	0.1072	0.366	0.79662	0.933	0.27452	0.543	1	1	0.21524	0.502
6p gain	39 (49%)	41	0.00018	0.00245	0.00425	0.0364	2e-04	0.00255	3e-04	0.0036	3e-05	0.00049	9.9999e-06	0.000185	0.01023	0.0759	3e-05	0.00049
6q gain	16 (20%)	64	0.0060899	0.0497	0.0024	0.0239	0.00029	0.00359	0.00098999	0.0109	0.00019	0.0025	0.00033	0.00385	0.00349	0.0316	0.00011	0.00155
7p gain	9 (11%)	71	0.16494	0.431	0.13064	0.401	1	1	0.73961	0.933	0.66059	0.889	0.1786	0.447	0.64145	0.872	0.78173	0.933
7q gain	8 (10%)	72	0.055239	0.24	0.03128	0.173	0.89043	0.989	0.44791	0.699	0.31517	0.593	0.32845	0.604	0.26122	0.543	0.67171	0.899
8p gain	33 (41%)	47	0.00134	0.0144	0.00084999	0.00963	0.00283	0.0269	0.00381	0.0338	0.01976	0.126	0.01442	0.0997	0.03801	0.188	0.01399	0.0984
8q gain	53 (66%)	27	9.9999e-06	0.000185	9.9999e-06	0.000185	3e-05	0.00049	9.9999e-06	0.000185	0.00011	0.00155	9.9999e-06	0.000185	9.9999e-06	0.000185	9.9999e-05	0.00151
9p gain	6 (8%)	74	0.23256	0.507	0.17861	0.447	0.40133	0.671	0.64321	0.872	0.74841	0.933	1	1	0.12483	0.389	0.91899	1
9q gain	5 (6%)	75	0.5088	0.763	0.03719	0.188	0.83767	0.951	0.83945	0.951	0.35097	0.621	0.75234	0.933	0.01856	0.123	0.75779	0.933
11p gain	9 (11%)	71	0.16288	0.431	0.54007	0.798	1	1	0.73759	0.933	0.2514	0.534	0.23538	0.508	1	1	0.70555	0.923
11q gain	10 (12%)	70	0.3171	0.593	0.82994	0.948	0.90927	0.999	0.82888	0.948	0.13526	0.406	0.11708	0.379	1	1	0.70096	0.922
12p gain	3 (4%)	77	0.16156	0.431	0.44071	0.695	0.089919	0.343	0.0101	0.0759	0.79814	0.933	0.27783	0.543	1	1	0.27948	0.543
12q gain	3 (4%)	77	0.16083	0.431	0.44067	0.695	0.087939	0.343	0.0095499	0.0735	0.79441	0.933	0.27249	0.543	1	1	0.28196	0.543
13q gain	6 (8%)	74	0.10509	0.366	1	1	0.73522	0.933	0.75191	0.933	0.48842	0.739	0.5171	0.77	0.40792	0.677	0.11932	0.381
14q gain	3 (4%)	77	0.03735	0.188	0.43803	0.695	0.59159	0.833	0.32658	0.603	0.7971	0.933	0.59642	0.833	1	1	0.76528	0.933
16p gain	4 (5%)	76	1	1	0.43553	0.695	1	1	0.43815	0.695	0.33867	0.617	0.47181	0.726	0.83118	0.948	1	1
17p gain	8 (10%)	72	0.081569	0.326	0.80296	0.933	0.3929	0.664	0.21889	0.502	0.35209	0.621	0.058239	0.245	0.48146	0.736	0.70249	0.922
17q gain	9 (11%)	71	0.21817	0.502	1	1	0.42035	0.692	0.31379	0.593	0.25307	0.535	0.02916	0.17	0.26382	0.543	0.63224	0.866
20p gain	8 (10%)	72	0.0091999	0.0722	0.56704	0.832	0.38974	0.663	0.21912	0.502	0.27761	0.543	0.23937	0.514	0.79118	0.933	0.84404	0.954
20q gain	9 (11%)	71	0.00172	0.018	0.54014	0.798	0.14414	0.424	0.058129	0.245	0.18234	0.454	0.15875	0.431	0.90451	0.997	0.7801	0.933
21q gain	14 (18%)	66	0.00283	0.0269	0.19882	0.483	0.10354	0.366	0.01372	0.0982	0.86724	0.975	0.29601	0.567	0.12578	0.389	0.46396	0.717
22q gain	6 (8%)	74	0.10506	0.366	0.64093	0.872	0.15026	0.431	0.2185	0.502	0.49248	0.741	0.17529	0.444	1	1	0.11953	0.381
xp gain	10 (12%)	70	0.38764	0.662	0.090689	0.343	0.11076	0.367	0.14045	0.418	0.33725	0.617	0.37464	0.647	0.37581	0.647	0.26499	0.543
xq gain	9 (11%)	71	0.65952	0.889	0.28232	0.543	0.02386	0.143	0.02027	0.127	0.10562	0.366	0.10284	0.366	0.43352	0.695	0.087629	0.343
1p loss	19 (24%)	61	0.00428	0.0364	0.051819	0.23	0.78323	0.933	0.66234	0.889	0.36621	0.639	0.27777	0.543	0.26453	0.543	0.076249	0.311
1q loss	3 (4%)	77	0.03809	0.188	0.17021	0.434	0.21776	0.502	0.32216	0.598	0.42998	0.695	0.04687	0.217	0.089319	0.343	0.03143	0.173
3p loss	43 (54%)	37	9.9999e-06	0.000185	9.9999e-06	0.000185	9.9999e-06	0.000185	9.9999e-06	0.000185	9.9999e-06	0.000185	9.9999e-06	0.000185	9.9999e-06	0.000185	9.9999e-06	0.000185
3q loss	43 (54%)	37	9.9999e-06	0.000185	9.9999e-06	0.000185	9.9999e-06	0.000185	9.9999e-06	0.000185	9.9999e-06	0.000185	9.9999e-06	0.000185	9.9999e-06	0.000185	9.9999e-06	0.000185
4q loss	3 (4%)	77	1	1	0.78968	0.933	0.58891	0.833	0.60041	0.833	0.79657	0.933	0.27405	0.543	0.40736	0.677	0.48937	0.739
5q loss	3 (4%)	77	0.4491	0.699	0.10935	0.366	0.090109	0.343	0.169	0.434	0.59573	0.833	0.87217	0.976	0.29791	0.568	0.89409	0.989
6q loss	17 (21%)	63	6.9999e-05	0.0011	0.00343	0.0316	0.04848	0.22	0.00457	0.0381	0.10006	0.366	0.2281	0.504	0.03942	0.191	0.00196	0.02
8p loss	9 (11%)	71	0.02999	0.172	0.34517	0.619	0.03763	0.188	0.02287	0.139	0.22819	0.504	0.28155	0.543	0.16114	0.431	0.01861	0.123
8q loss	3 (4%)	77	0.78781	0.933	0.60283	0.833	1	1	0.79101	0.933	1	1	0.77334	0.933	0.7865	0.933	0.89341	0.989
9p loss	8 (10%)	72	0.10861	0.366	0.04046	0.194	0.34815	0.62	0.15426	0.431	0.1859	0.457	0.35321	0.621	0.17007	0.434	0.79237	0.933
9q loss	7 (9%)	73	0.16394	0.431	0.074029	0.305	0.59187	0.833	0.24255	0.518	0.095159	0.354	0.58354	0.833	0.078769	0.318	0.41808	0.691
11p loss	3 (4%)	77	0.03818	0.188	0.23512	0.508	0.04412	0.209	0.10815	0.366	0.22958	0.504	0.15199	0.431	0.21418	0.502	0.18424	0.456
12p loss	3 (4%)	77	0.78736	0.933	0.6067	0.833	1	1	0.7915	0.933	1	1	0.51595	0.77	0.5915	0.833	1	1
13q loss	3 (4%)	77	1	1	0.1692	0.434	0.59215	0.833	0.60326	0.833	1	1	1	1	0.78598	0.933	0.48743	0.739
15q loss	4 (5%)	76	0.15813	0.431	0.04997	0.224	0.83187	0.948	0.8238	0.948	1	1	0.91099	0.999	1	1	0.69579	0.922
16p loss	3 (4%)	77	1	1	0.44073	0.695	0.59006	0.833	0.60152	0.833	1	1	1	1	0.78522	0.933	0.35465	0.621
16q loss	16 (20%)	64	0.02127	0.131	0.13224	0.403	0.095519	0.354	0.01323	0.0964	0.82318	0.948	0.12509	0.389	0.14429	0.424	0.04774	0.219
19p loss	3 (4%)	77	0.45147	0.7	0.60482	0.833	0.78339	0.933	1	1	0.59583	0.833	0.2288	0.504	0.78477	0.933	0.69157	0.919
19q loss	3 (4%)	77	0.44891	0.699	0.60394	0.833	0.78114	0.933	1	1	0.59958	0.833	0.22811	0.504	0.78615	0.933	0.69152	0.919
xp loss	12 (15%)	68	0.34	0.617	0.0376	0.188	0.32265	0.598	0.26356	0.543	0.48114	0.736	0.57918	0.833	0.069999	0.291	0.13512	0.406
xq loss	13 (16%)	67	0.15528	0.431	0.01897	0.123	0.21052	0.502	0.14547	0.424	0.22121	0.504	0.38493	0.66	0.01873	0.123	0.04661	0.217
