Clinical Features Time to Death YEARS_TO_BIRTH PATHOLOGIC_STAGE PATHOLOGY_T_STAGE PATHOLOGY_N_STAGE GENDER RADIATION_THERAPY HISTOLOGICAL_TYPE RESIDUAL_TUMOR NUMBER_OF_LYMPH_NODES ETHNICITY nMutated (%) nWild-Type logrank test_P logrank test_Q Wilcoxon-test_P Wilcoxon-test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Wilcoxon-test_P Wilcoxon-test_Q Fisher's exact test_P Fisher's exact test_Q ZFPM1 24 (39%) 38 0.30135 1 0.53413 1 0.31924 1 0.97374 1 0.66624 1 1 1 0.75867 1 1 1 0.1439 1 0.33009 1 0.67692 1 LACTB 19 (31%) 43 0.92281 1 0.94519 1 0.19279 1 0.10662 1 1 1 0.56782 1 1 1 0.189 1 1 1 0.90056 1 0.65598 1 CCDC102A 17 (27%) 45 0.10396 1 0.47745 1 0.14635 1 0.20962 1 0.17026 1 1 1 0.73693 1 0.16733 1 0.7792 1 0.31034 1 1 1 ZNF517 13 (21%) 49 0.96764 1 0.042075 1 0.73764 1 0.7539 1 1 1 0.75624 1 0.12822 1 0.61901 1 0.41922 1 0.70482 1 0.30578 1 MAL2 11 (18%) 51 0.7272 1 0.070821 1 0.45087 1 0.04685 1 0.3017 1 0.078935 1 0.70745 1 1 1 0.80144 1 0.2352 1 0.29969 1 TOR3A 12 (19%) 50 0.43136 1 0.53269 1 0.18499 1 0.13702 1 0.58102 1 0.73958 1 1 1 1 1 0.15152 1 0.40461 1 1 1 TP53 13 (21%) 49 0.032907 1 0.91733 1 0.099959 1 0.23485 1 1 1 0.51549 1 1 1 1 1 0.0088899 1 0.40461 1 0.13462 1 CLDN23 10 (16%) 52 0.99727 1 0.716 1 0.6222 1 0.75169 1 0.25938 1 0.47182 1 1 1 0.21731 1 0.26242 1 0.70482 1 0.5585 1 GDF1 5 (8%) 57 0.10133 1 0.94844 1 0.36947 1 0.54688 1 1 1 1 1 0.58169 1 1 1 1 1 0.40461 1 1 1 LZTR1 6 (10%) 56 0.53616 1 0.46025 1 1 1 1 1 0.48412 1 1 1 0.13296 1 1 1 0.82703 1 0.94608 1 1 1 ANKRD43 19 (31%) 43 0.58704 1 0.37561 1 0.62647 1 0.79415 1 0.33789 1 0.39518 1 1 1 1 1 0.14225 1 0.40852 1 0.17797 1 KCNK17 9 (15%) 53 0.53954 1 0.71895 1 0.85022 1 0.4295 1 0.5847 1 0.70862 1 0.42341 1 1 1 0.55602 1 0.31034 1 0.18007 1 RINL 8 (13%) 54 0.36203 1 0.62153 1 0.61536 1 0.51393 1 1 1 0.70029 1 0.013155 1 1 1 0.70163 1 0.76786 1 0.26837 1 ZAR1 11 (18%) 51 0.28852 1 0.67156 1 0.65595 1 0.33269 1 0.3017 1 0.078935 1 0.70745 1 0.01557 1 0.80064 1 0.10454 1 0.5585 1 CTNNB1 8 (13%) 54 0.20764 1 0.3776 1 0.42789 1 0.48453 1 0.17805 1 0.04207 1 1 1 1 1 0.24234 1 0.94608 1 1 1 APOE 7 (11%) 55 0.84354 1 0.13307 1 1 1 0.92184 1 1 1 0.086091 1 0.13296 1 1 1 0.12611 1 NA NA 1 1 GPRIN2 8 (13%) 54 0.5789 1 0.40073 1 0.94427 1 0.58054 1 0.5847 1 1 1 0.37399 1 1 1 0.70368 1 0.40461 1 1 1 ASPDH 8 (13%) 54 0.40904 1 0.98324 1 0.00286 1 0.3106 1 0.1051 1 0.70029 1 0.0057317 1 1 1 0.12561 1 0.44866 1 1 1 ERCC2 10 (16%) 52 0.51974 1 0.83318 1 0.60135 1 0.63142 1 0.25938 1 1 1 0.22206 1 1 1 1 1 0.90056 1 0.5112 1 IDUA 8 (13%) 54 0.31883 1 0.20374 1 0.10874 1 0.23371 1 1 1 1 1 0.66686 1 0.43067 1 0.85439 1 0.40461 1 1 1 C1ORF106 9 (15%) 53 0.26574 1 0.38448 1 0.51417 1 0.30685 1 0.21798 1 0.14043 1 0.67052 1 1 1 1 1 0.94608 1 0.5585 1 C10ORF95 6 (10%) 56 0.56463 1 0.53569 1 0.36293 1 0.70365 1 1 1 1 1 1 1 0.11664 1 0.82605 1 NA NA 1 1 RGS9BP 8 (13%) 54 0.46553 1 0.98324 1 0.93841 1 0.03484 1 0.54144 1 0.43805 1 0.37399 1 1 1 1 1 0.54443 1 0.5112 1 THEM4 5 (8%) 57 0.67136 1 0.31312 1 0.4791 1 0.38625 1 0.35146 1 0.64731 1 1 1 1 1 0.72354 1 NA NA 1 1 TSC22D2 8 (13%) 54 0.021849 1 0.62897 1 0.27406 1 0.11311 1 1 1 0.70029 1 0.37399 1 0.16765 1 0.25866 1 0.40461 1 0.5112 1 SYT8 8 (13%) 54 0.34936 1 0.40665 1 0.23096 1 0.69015 1 0.5847 1 1 1 1 1 1 1 0.62616 1 NA NA 0.5585 1 PLIN5 5 (8%) 57 0.43431 1 0.58703 1 1 1 0.89493 1 0.42095 1 0.64731 1 0.077778 1 1 1 1 1 0.70482 1 0.37433 1 LRIG1 16 (26%) 46 0.62374 1 0.45908 1 0.91495 1 0.74359 1 0.15876 1 0.37529 1 0.73966 1 0.38203 1 0.75282 1 0.78675 1 0.64446 1 HHIPL1 6 (10%) 56 0.97715 1 0.60024 1 0.73077 1 0.64125 1 0.48412 1 0.65659 1 0.13296 1 1 1 0.68673 1 0.70482 1 1 1 CCDC105 6 (10%) 56 0.60467 1 0.43182 1 0.28039 1 0.10432 1 0.48412 1 0.080787 1 0.32006 1 1 1 1 1 NA NA 0.5112 1 C19ORF10 7 (11%) 55 0.92538 1 0.53323 1 0.1471 1 0.47651 1 0.54144 1 0.40475 1 0.33747 1 1 1 0.49497 1 0.94608 1 1 1 OPRD1 12 (19%) 50 0.90709 1 0.139 1 1 1 1 1 1 1 0.5123 1 0.44834 1 1 1 0.93574 1 0.95018 1 1 1 ATXN1 10 (16%) 52 0.84834 1 0.26265 1 0.74802 1 0.4282 1 1 1 0.082016 1 0.42664 1 1 1 0.26538 1 0.40461 1 1 1 AATK 6 (10%) 56 0.29852 1 0.034003 1 0.68358 1 0.70767 1 0.48412 1 0.40908 1 1 1 0.34373 1 1 1 NA NA 1 1 ZNF628 7 (11%) 55 0.022416 1 0.75539 1 0.43367 1 0.41262 1 1 1 1 1 0.61668 1 1 1 0.25866 1 NA NA 0.5112 1 KRTAP4-5 5 (8%) 57 0.13515 1 0.47692 1 0.57384 1 0.30817 1 1 1 0.64731 1 0.32876 1 1 1 1 1 NA NA 1 1 NOXA1 5 (8%) 57 0.21371 1 0.98968 1 0.89838 1 0.7975 1 0.42095 1 0.15097 1 1 1 1 1 1 1 0.40461 1 1 1 TRIOBP 10 (16%) 52 0.74873 1 0.76662 1 0.9533 1 1 1 0.052374 1 0.082016 1 0.68506 1 1 1 0.64704 1 0.40852 1 1 1 ZNF598 12 (19%) 50 0.37051 1 0.020975 1 0.51544 1 0.86442 1 0.58102 1 0.018637 1 1 1 0.58625 1 0.80087 1 0.31034 1 0.57981 1 IRX3 5 (8%) 57 0.63744 1 0.31312 1 0.238 1 0.50221 1 1 1 0.64731 1 0.56418 1 1 1 0.080429 1 NA NA 1 1 WDR34 5 (8%) 57 0.5252 1 0.679 1 1 1 0.73505 1 1 1 0.049287 1 0.58169 1 0.29183 1 0.28745 1 NA NA 1 1 BHLHE22 5 (8%) 57 0.26374 1 0.92787 1 0.28954 1 0.89534 1 0.073514 1 0.64731 1 0.58169 1 1 1 0.051649 1 0.44866 1 0.18007 1 PANK2 5 (8%) 57 0.0097828 1 0.16644 1 0.8974 1 0.62064 1 1 1 0.049287 1 1 1 1 1 0.04204 1 NA NA 1 1 FPGS 5 (8%) 57 0.13034 1 0.31936 1 0.23859 1 0.56166 1 0.42095 1 1 1 1 1 1 1 0.24979 1 NA NA 1 1 GLTPD2 6 (10%) 56 0.41171 1 0.10025 1 0.62932 1 0.62198 1 1 1 0.65659 1 0.13296 1 0.3411 1 0.40712 1 NA NA 0.20588 1 TNIP2 5 (8%) 57 0.42057 1 0.60496 1 0.085469 1 0.63671 1 0.046264 1 1 1 0.077778 1 1 1 0.72138 1 NA NA 1 1 AKAP2 6 (10%) 56 0.56415 1 0.88635 1 0.35563 1 0.91998 1 1 1 0.1736 1 1 1 0.34029 1 0.04484 1 NA NA 1 1 RREB1 5 (8%) 57 0.83897 1 0.93815 1 0.63112 1 0.23156 1 0.073514 1 1 1 0.58169 1 1 1 0.24783 1 0.26076 1 0.37433 1 TPO 12 (19%) 50 0.91438 1 0.85153 1 0.86419 1 0.95285 1 0.087936 1 1 1 0.26377 1 0.58338 1 1 1 0.21146 1 1 1 OBSCN 18 (29%) 44 0.83155 1 0.045341 1 0.43607 1 0.83705 1 0.33789 1 0.56134 1 0.19 1 0.68055 1 0.42069 1 0.69134 1 1 1 SNED1 5 (8%) 57 0.29555 1 0.73669 1 0.12998 1 0.15976 1 0.073514 1 0.64731 1 0.077778 1 1 1 1 1 NA NA 1 1 MEN1 5 (8%) 57 0.12836 1 0.6885 1 0.03314 1 0.15144 1 0.35146 1 1 1 0.58169 1 1 1 0.053749 1 NA NA 0.5112 1 BTBD11 6 (10%) 56 0.97568 1 0.86757 1 0.03695 1 0.14239 1 0.48412 1 0.40908 1 0.61668 1 1 1 1 1 0.44866 1 1 1 RNF149 4 (6%) 58 0.14255 1 0.070917 1 0.23058 1 0.38367 1 1 1 1 1 0.56418 1 1 1 1 1 NA NA 1 1 KIAA1984 4 (6%) 58 0.8698 1 0.6568 1 0.8323 1 0.51496 1 1 1 0.12354 1 0.22954 1 1 1 1 1 NA NA 0.5112 1 CCDC150 4 (6%) 58 0.099318 1 0.45607 1 0.03334 1 0.10674 1 0.35146 1 1 1 0.22954 1 1 1 0.077349 1 0.70482 1 0.1006 1 FAM18B2 4 (6%) 58 0.39014 1 0.62602 1 1 1 0.46303 1 0.35146 1 1 1 0.03639 1 1 1 0.72002 1 NA NA 0.37433 1 MUC5B 22 (35%) 40 0.61672 1 0.58097 1 0.73559 1 0.8014 1 0.4122 1 1 1 0.7514 1 0.21949 1 0.62646 1 0.086914 1 1 1 PTPLA 4 (6%) 58 0.6699 1 0.72009 1 0.60635 1 0.63917 1 1 1 0.61036 1 1 1 1 1 0.72134 1 NA NA 0.5112 1 SRPX 3 (5%) 59 0.82841 1 0.92157 1 0.83225 1 0.62344 1 0.27516 1 0.54627 1 0.5564 1 1 1 0.61374 1 0.44866 1 0.5112 1 GARS 19 (31%) 43 0.045806 1 0.22458 1 0.0079099 1 0.0068499 1 0.65793 1 1 1 0.045451 1 0.082089 1 0.37617 1 0.2352 1 0.64446 1 PRSS27 3 (5%) 59 0.2152 1 0.41193 1 0.46608 1 0.51671 1 1 1 0.28503 1 0.13296 1 1 1 0.6114 1 NA NA 0.037433 1 SEMA5B 8 (13%) 54 0.73145 1 0.64396 1 0.85166 1 1 1 1 1 0.43805 1 1 1 0.43507 1 0.43842 1 0.70482 1 1 1 CD320 4 (6%) 58 0.40205 1 0.28237 1 0.15211 1 0.2732 1 1 1 1 1 1 1 1 1 0.28794 1 NA NA 0.1006 1 TAF5 4 (6%) 58 0.36884 1 0.59588 1 0.32288 1 0.84225 1 0.35146 1 1 1 1 1 1 1 0.16295 1 NA NA 0.37433 1 NEFH 6 (10%) 56 0.23398 1 0.53569 1 1 1 0.36981 1 0.48412 1 1 1 0.61668 1 1 1 1 1 1 1 0.18007 1 DMKN 3 (5%) 59 0.18372 1 0.38445 1 NA NA NA NA 1 1 1 1 0.5564 1 1 1 NA NA NA NA 1 1 NPTX1 3 (5%) 59 0.88186 1 0.89555 1 0.24681 1 0.24087 1 1 1 0.28503 1 1 1 1 1 0.61362 1 NA NA 1 1 NOTCH2 5 (8%) 57 0.43915 1 0.76613 1 0.68523 1 0.46435 1 0.35146 1 1 1 0.077778 1 1 1 1 1 0.94608 1 1 1 RNF39 5 (8%) 57 0.83105 1 0.77602 1 0.32006 1 0.8441 1 0.35146 1 1 1 0.58169 1 1 1 0.28722 1 NA NA 0.37433 1 KBTBD13 9 (15%) 53 0.32805 1 0.49667 1 0.087189 1 0.11045 1 0.21798 1 0.14043 1 1 1 1 1 0.74098 1 0.34867 1 1 1 IER5 3 (5%) 59 0.00019899 0.254 0.58814 1 0.088909 1 0.03461 1 0.27516 1 0.54627 1 0.13296 1 1 1 0.089179 1 NA NA 1 1 SCRT1 3 (5%) 59 0.035315 1 0.22462 1 0.83408 1 0.32996 1 0.27516 1 0.54627 1 0.5564 1 1 1 0.16934 1 NA NA 1 1 KNDC1 9 (15%) 53 0.2964 1 0.91244 1 0.1279 1 0.067179 1 1 1 0.14043 1 1 1 1 1 1 1 0.40461 1 1 1 MAP1S 5 (8%) 57 0.71856 1 0.40058 1 0.38757 1 1 1 0.42095 1 0.3366 1 0.58169 1 0.29142 1 0.11885 1 NA NA 1 1 RGMB 6 (10%) 56 0.82693 1 0.72979 1 1 1 0.70581 1 0.48412 1 1 1 0.32006 1 1 1 1 1 NA NA 0.30578 1 LRP11 6 (10%) 56 0.62826 1 0.49721 1 0.75487 1 1 1 1 1 0.65659 1 1 1 1 1 0.59957 1 NA NA 0.5585 1 AR 4 (6%) 58 0.12749 1 0.78536 1 0.32243 1 0.15347 1 0.35146 1 1 1 1 1 0.23951 1 0.053709 1 NA NA 1 1 VARS 6 (10%) 56 0.99452 1 0.83955 1 0.31975 1 0.23618 1 1 1 0.1736 1 0.13296 1 1 1 1 1 0.40461 1 0.021132 1 SEZ6L2 8 (13%) 54 0.44015 1 0.88309 1 0.85344 1 0.61209 1 1 1 1 1 1 1 1 1 1 1 0.44866 1 0.30578 1 PABPC1 4 (6%) 58 0.62588 1 0.39774 1 1 1 1 1 0.35146 1 0.61036 1 1 1 1 1 1 1 NA NA 0.5585 1 FANK1 3 (5%) 59 0.79579 1 0.38445 1 0.01028 1 0.04796 1 0.27516 1 0.54627 1 1 1 1 1 0.61563 1 NA NA 1 1 NMU 5 (8%) 57 0.42693 1 0.27167 1 1 1 0.89529 1 0.42095 1 0.15097 1 0.58169 1 1 1 0.40627 1 0.54443 1 0.5112 1 ADAD2 4 (6%) 58 0.9917 1 0.62602 1 0.83168 1 1 1 1 1 0.12354 1 0.5564 1 0.073989 1 0.39064 1 NA NA 1 1 CLIC6 5 (8%) 57 0.28506 1 0.34515 1 0.46983 1 0.70795 1 1 1 0.64731 1 0.32876 1 1 1 1 1 NA NA 1 1 PCDHB13 5 (8%) 57 0.78437 1 0.12701 1 0.34896 1 0.20555 1 1 1 1 1 0.32876 1 1 1 0.40304 1 NA NA 0.1006 1 PLEC 13 (21%) 49 0.57113 1 0.56806 1 0.82112 1 0.79254 1 1 1 0.11215 1 0.47786 1 1 1 0.60044 1 1 1 0.64446 1 AMDHD1 10 (16%) 52 0.33015 1 0.043373 1 0.82457 1 1 1 0.57771 1 0.3066 1 0.19277 1 1 1 0.90417 1 NA NA 0.5112 1 DSPP 9 (15%) 53 0.85222 1 0.4124 1 0.68964 1 1 1 0.21798 1 0.47135 1 0.66686 1 1 1 0.66718 1 0.68489 1 1 1 TMEM189 3 (5%) 59 0.19293 1 0.44055 1 NA NA NA NA 1 1 1 1 0.5564 1 1 1 NA NA NA NA 0.37433 1 CRIPAK 10 (16%) 52 0.51419 1 0.11639 1 0.097889 1 0.32533 1 0.57679 1 1 1 0.097699 1 1 1 0.48829 1 NA NA 1 1 PDCD6 3 (5%) 59 0.78109 1 0.087891 1 0.0097199 1 0.00483 1 0.27516 1 1 1 1 1 1 1 0.60935 1 NA NA 0.20588 1 MAP7 3 (5%) 59 0.97294 1 0.73039 1 1 1 1 1 1 1 1 1 0.5564 1 1 1 1 1 NA NA 1 1 NOM1 6 (10%) 56 0.93441 1 0.62532 1 0.20813 1 0.26008 1 1 1 1 1 0.32006 1 1 1 0.68181 1 NA NA 1 1 SHOX2 3 (5%) 59 0.20499 1 0.89555 1 1 1 0.78316 1 0.27516 1 1 1 0.5564 1 0.18553 1 1 1 NA NA 1 1 HSD17B1 4 (6%) 58 0.59018 1 0.59588 1 0.18564 1 0.2307 1 1 1 1 1 0.22954 1 1 1 0.50428 1 NA NA 0.37433 1 PRKAR1A 6 (10%) 56 0.90485 1 0.83025 1 0.059119 1 0.062859 1 0.48412 1 0.080787 1 1 1 1 1 0.68545 1 0.70482 1 0.37433 1 KRTAP5-5 3 (5%) 59 0.35918 1 0.066076 1 0.83326 1 1 1 1 1 0.28503 1 0.5564 1 1 1 1 1 NA NA 1 1 DLEU7 3 (5%) 59 0.39796 1 0.61096 1 0.83353 1 1 1 1 1 1 1 1 1 1 1 0.61372 1 NA NA 1 1 FEZ2 3 (5%) 59 0.73947 1 0.49069 1 0.8325 1 0.7876 1 0.27516 1 1 1 1 1 1 1 0.61249 1 NA NA 1 1 RASIP1 6 (10%) 56 0.11117 1 0.9905 1 0.64236 1 0.47586 1 0.48412 1 0.40908 1 0.61668 1 1 1 0.092999 1 NA NA 1 1 JMJD4 3 (5%) 59 0.90716 1 0.84389 1 1 1 0.62414 1 1 1 0.28503 1 1 1 1 1 0.39487 1 NA NA 0.37433 1 COQ2 5 (8%) 57 0.72077 1 0.12382 1 0.47042 1 0.70592 1 1 1 0.64731 1 1 1 0.29057 1 0.60223 1 NA NA 1 1 UQCRFS1 5 (8%) 57 0.25686 1 0.049335 1 0.03572 1 0.02056 1 0.42095 1 1 1 0.32876 1 1 1 0.04178 1 NA NA 0.18007 1 C9ORF66 5 (8%) 57 0.2451 1 0.35852 1 0.42777 1 0.56224 1 1 1 0.3366 1 0.58169 1 1 1 1 1 NA NA 0.037433 1 POLRMT 4 (6%) 58 0.10775 1 0.81861 1 0.22823 1 0.38905 1 1 1 0.61036 1 0.56418 1 0.24108 1 1 1 NA NA NA NA ADAMTS7 4 (6%) 58 0.15598 1 0.12868 1 0.23084 1 0.38669 1 1 1 1 1 1 1 0.23823 1 1 1 NA NA 1 1 BTNL9 4 (6%) 58 0.70187 1 0.50052 1 0.8341 1 1 1 1 1 1 1 1 1 1 1 0.39166 1 NA NA 1 1 NF1 7 (11%) 55 0.27859 1 0.68057 1 1 1 1 1 1 1 0.0064154 1 0.13296 1 1 1 0.26519 1 NA NA 0.5112 1 ZNF814 3 (5%) 59 0.23054 1 0.74276 1 0.02593 1 0.064169 1 1 1 1 1 1 1 1 1 0.17193 1 NA NA 1 1 RNF135 3 (5%) 59 0.20499 1 0.83107 1 0.57233 1 0.7844 1 1 1 1 1 1 1 1 1 1 1 NA NA 0.5112 1 CSGALNACT2 3 (5%) 59 0.83653 1 0.70586 1 0.83353 1 1 1 1 1 0.54627 1 1 1 1 1 0.61158 1 NA NA 1 1 SPIRE2 3 (5%) 59 0.82203 1 0.063693 1 0.38727 1 0.15975 1 1 1 0.54627 1 1 1 1 1 0.39122 1 NA NA 0.20588 1 CYP4A22 4 (6%) 58 0.066787 1 0.82977 1 0.32082 1 0.84367 1 1 1 0.61036 1 1 1 1 1 0.72055 1 NA NA 0.5112 1 HLA-A 3 (5%) 59 0.30716 1 0.22462 1 1 1 0.62333 1 1 1 0.28503 1 0.5564 1 1 1 1 1 NA NA 0.20588 1 GLI3 5 (8%) 57 0.11381 1 0.96905 1 0.01854 1 0.0068399 1 1 1 0.64731 1 0.58169 1 1 1 0.051769 1 NA NA 1 1