Ras signaling in the CD4+ TCR pathway Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations ERK1-2/ELK1 -0.046 0.218 0.334 1.0 -0.488 11.0 12.0 MAP3K8 0.015 0.081 0.248 2.0 -0.422 2.0 4.0 FOS -0.05 0.211 0.306 2.0 -0.475 11.0 13.0 PRKCA -0.018 0.131 0.241 1.0 -0.422 7.0 8.0 PTPN7 0.032 0.182 0.241 20.0 -0.423 8.0 28.0 HRAS 0.023 0.005 -9999.0 0.0 -9999.0 0.0 0.0 PRKCB 0.015 0.134 0.241 8.0 -0.424 5.0 13.0 NRAS 0.023 0.005 -9999.0 0.0 -9999.0 0.0 0.0 RAS family/GTP 0.038 0.021 -9999.0 0.0 -9999.0 0.0 0.0 MAPK3 -0.015 0.193 0.313 1.0 -0.539 7.0 8.0 MAP2K1 -0.058 0.192 -9999.0 0.0 -0.413 14.0 14.0 ELK1 0.022 0.014 -9999.0 0.0 -9999.0 0.0 0.0 BRAF -0.045 0.164 -9999.0 0.0 -0.385 13.0 13.0 mol:GTP -0.0 0.001 0.003 2.0 -0.004 4.0 6.0 MAPK1 -0.061 0.221 0.281 1.0 -0.467 14.0 15.0 RAF1 -0.038 0.162 -9999.0 0.0 -0.387 12.0 12.0 KRAS 0.022 0.006 -9999.0 0.0 -9999.0 0.0 0.0