Signaling events mediated by the Hedgehog family
Entity	Mean	Std Dev	Mean of Up Perturbations	Number of Up Perturbations	Mean of Down Perturbations	Number of Down Perturbations	Number of Total Perturbations
TGFB2	-0.04	0.22	0.412	5.0	-0.621	115.0	120.0
IHH	0.016	0.082	0.264	31.0	-0.195	93.0	124.0
SHH Np/Cholesterol/GAS1	0.0	0.075	-9999.0	0.0	-0.328	49.0	49.0
LRPAP1	0.023	0.005	-9999.0	0.0	-9999.0	0.0	0.0
dorsoventral neural tube patterning	-0.0	0.075	0.326	49.0	-9999.0	0.0	49.0
SMO/beta Arrestin2	-0.019	0.209	0.3	1.0	-0.604	102.0	103.0
SMO	-0.042	0.212	0.319	1.0	-0.585	121.0	122.0
AKT1	-0.004	0.133	-9999.0	0.0	-0.617	23.0	23.0
ARRB2	0.022	0.007	-9999.0	0.0	-9999.0	0.0	0.0
BOC	-0.018	0.151	-9999.0	0.0	-0.566	76.0	76.0
ADRBK1	0.023	0.006	-9999.0	0.0	-9999.0	0.0	0.0
heart looping	-0.041	0.208	0.318	1.0	-0.574	121.0	122.0
STIL	0.006	0.173	0.298	30.0	-0.464	92.0	122.0
DHH N/PTCH2	-0.008	0.14	-9999.0	0.0	-0.44	98.0	98.0
DHH N/PTCH1	-0.027	0.205	0.275	1.0	-0.503	146.0	147.0
PIK3CA	0.023	0.005	-9999.0	0.0	-9999.0	0.0	0.0
DHH	0.008	0.096	0.255	2.0	-0.566	29.0	31.0
PTHLH	-0.061	0.297	0.42	14.0	-0.818	123.0	137.0
determination of left/right symmetry	-0.041	0.208	0.318	1.0	-0.574	121.0	122.0
PIK3R1	0.016	0.065	-9999.0	0.0	-0.566	13.0	13.0
skeletal system development	-0.059	0.293	0.42	14.0	-0.806	123.0	137.0
IHH N/Hhip	0.027	0.056	0.212	7.0	-0.298	4.0	11.0
DHH N/Hhip	0.022	0.077	-9999.0	0.0	-0.414	31.0	31.0
mol:Cholesterol	-0.0	0.0	-9999.0	0.0	-9999.0	0.0	0.0
heart development	-0.041	0.208	0.318	1.0	-0.574	121.0	122.0
pancreas development	0.023	0.03	0.255	5.0	-0.565	2.0	7.0
HHAT	0.02	0.02	-9999.0	0.0	-0.566	1.0	1.0
PI3K	0.028	0.049	-9999.0	0.0	-0.385	14.0	14.0
EntrezGene:84976	-0.0	0.0	-9999.0	0.0	-9999.0	0.0	0.0
GAS1	-0.009	0.137	-9999.0	0.0	-0.566	61.0	61.0
somite specification	-0.041	0.208	0.318	1.0	-0.574	121.0	122.0
SHH Np/Cholesterol/PTCH1	-0.024	0.159	0.253	5.0	-0.436	119.0	124.0
SHH Np/Cholesterol/PTCH2	-0.004	0.082	-9999.0	0.0	-0.329	59.0	59.0
SHH Np/Cholesterol/Megalin	-0.06	0.147	0.277	3.0	-0.329	229.0	232.0
SHH	-0.0	0.037	0.341	7.0	-0.423	1.0	8.0
catabolic process	-0.033	0.208	0.294	3.0	-0.564	126.0	129.0
SMO/Vitamin D3	-0.009	0.198	0.339	21.0	-0.501	118.0	139.0
SHH Np/Cholesterol/Hhip	0.015	0.028	0.248	3.0	-0.333	3.0	6.0
LRP2	-0.123	0.264	0.255	26.0	-0.566	277.0	303.0
receptor-mediated endocytosis	-0.079	0.221	0.303	11.0	-0.575	119.0	130.0
SHH Np/Cholesterol/BOC	-0.004	0.083	-9999.0	0.0	-0.329	61.0	61.0
SHH Np/Cholesterol/CDO	0.013	0.04	-9999.0	0.0	-0.33	12.0	12.0
mesenchymal cell differentiation	-0.015	0.028	0.331	3.0	-0.245	3.0	6.0
mol:Vitamin D3	0.002	0.18	0.333	24.0	-0.448	113.0	137.0
IHH N/PTCH2	-0.006	0.137	0.209	3.0	-0.459	79.0	82.0
CDON	0.015	0.065	-9999.0	0.0	-0.566	13.0	13.0
IHH N/PTCH1	-0.024	0.214	0.35	4.0	-0.568	126.0	130.0
Megalin/LRPAP1	-0.079	0.201	-9999.0	0.0	-0.418	277.0	277.0
PTCH2	-0.018	0.151	-9999.0	0.0	-0.566	76.0	76.0
SHH Np/Cholesterol	0.01	0.013	-9999.0	0.0	-0.329	1.0	1.0
PTCH1	-0.033	0.209	0.295	3.0	-0.566	126.0	129.0
HHIP	0.023	0.03	0.255	5.0	-0.566	2.0	7.0