This pipeline computes the correlation between significant copy number variation (cnv focal) genes and selected clinical features.
Testing the association between copy number variation 63 focal events and 39 clinical features across 295 patients, 9 significant findings detected with Q value < 0.25.
-
amp_11q22.1 cnv correlated to 'YEARS_TO_BIRTH' and 'AGE_AT_DIAGNOSIS'.
-
del_3p14.2 cnv correlated to 'HISTOLOGICAL_TYPE' and 'TOBACCO_SMOKING_HISTORY'.
-
del_6q26 cnv correlated to 'INITIAL_PATHOLOGIC_DX_YEAR'.
-
del_10q23.31 cnv correlated to 'YEARS_TO_BIRTH'.
-
del_16q11.2 cnv correlated to 'HISTOLOGICAL_TYPE'.
-
del_16q23.1 cnv correlated to 'HISTOLOGICAL_TYPE'.
-
del_18q21.2 cnv correlated to 'HISTOLOGICAL_TYPE'.
Clinical Features |
Time to Death |
YEARS TO BIRTH |
PATHOLOGY T STAGE |
PATHOLOGY N STAGE |
PATHOLOGY M STAGE |
RADIATION THERAPY |
HISTOLOGICAL TYPE |
NUMBER PACK YEARS SMOKED |
NUMBER OF LYMPH NODES |
RACE | ETHNICITY |
WEIGHT KG AT DIAGNOSIS |
TUMOR STATUS |
NEOPLASM HISTOLOGIC GRADE |
TOBACCO SMOKING YEAR STOPPED |
TOBACCO SMOKING PACK YEARS SMOKED |
TOBACCO SMOKING HISTORY |
AGEBEGANSMOKINGINYEARS |
RADIATION THERAPY STATUS |
PREGNANCIES COUNT TOTAL |
PREGNANCIES COUNT STILLBIRTH |
PREGNANCY SPONTANEOUS ABORTION COUNT |
PREGNANCIES COUNT LIVE BIRTH |
PREGNANCY THERAPEUTIC ABORTION COUNT |
PREGNANCIES COUNT ECTOPIC |
POS LYMPH NODE LOCATION |
MENOPAUSE STATUS |
LYMPHOVASCULAR INVOLVEMENT |
LYMPH NODES EXAMINED HE COUNT |
LYMPH NODES EXAMINED |
KERATINIZATION SQUAMOUS CELL |
INITIAL PATHOLOGIC DX YEAR |
HISTORY HORMONAL CONTRACEPTIVES USE |
HEIGHT CM AT DIAGNOSIS |
CORPUS INVOLVEMENT |
CHEMO CONCURRENT TYPE |
CERVIX SUV RESULTS |
AGE AT DIAGNOSIS |
CLINICAL STAGE |
||
nCNV (%) | nWild-Type | logrank test | Wilcoxon-test | Fisher's exact test | Fisher's exact test | Fisher's exact test | Fisher's exact test | Fisher's exact test | Wilcoxon-test | Wilcoxon-test | Fisher's exact test | Fisher's exact test | Wilcoxon-test | Fisher's exact test | Fisher's exact test | Wilcoxon-test | Wilcoxon-test | Fisher's exact test | Wilcoxon-test | Fisher's exact test | Wilcoxon-test | Wilcoxon-test | Wilcoxon-test | Wilcoxon-test | Wilcoxon-test | Wilcoxon-test | Fisher's exact test | Fisher's exact test | Fisher's exact test | Wilcoxon-test | Wilcoxon-test | Fisher's exact test | Wilcoxon-test | Fisher's exact test | Wilcoxon-test | Fisher's exact test | Fisher's exact test | Wilcoxon-test | Wilcoxon-test | Fisher's exact test | |
amp 11q22 1 | 47 (16%) | 248 |
0.824 (1.00) |
0.000111 (0.0456) |
0.386 (0.921) |
1 (1.00) |
1 (1.00) |
0.637 (0.97) |
0.686 (0.981) |
0.0211 (0.452) |
0.965 (1.00) |
0.0234 (0.471) |
0.38 (0.921) |
0.285 (0.869) |
1 (1.00) |
0.0251 (0.486) |
0.279 (0.866) |
0.0211 (0.452) |
0.64 (0.971) |
0.69 (0.981) |
1 (1.00) |
0.947 (1.00) |
0.23 (0.84) |
0.512 (0.953) |
0.994 (1.00) |
0.436 (0.943) |
0.351 (0.906) |
0.924 (1.00) |
0.00215 (0.352) |
0.519 (0.953) |
0.965 (1.00) |
0.434 (0.94) |
0.274 (0.866) |
0.00252 (0.378) |
0.717 (0.988) |
0.172 (0.774) |
0.191 (0.792) |
0.308 (0.885) |
0.147 (0.749) |
9.19e-05 (0.0451) |
0.599 (0.969) |
del 3p14 2 | 134 (45%) | 161 |
0.668 (0.981) |
0.993 (1.00) |
0.0291 (0.504) |
0.00575 (0.416) |
0.752 (0.996) |
0.0719 (0.661) |
8e-05 (0.0451) |
0.61 (0.969) |
0.00323 (0.378) |
0.872 (1.00) |
0.262 (0.857) |
0.0114 (0.444) |
0.127 (0.712) |
0.127 (0.712) |
0.0982 (0.692) |
0.61 (0.969) |
0.00053 (0.186) |
0.639 (0.971) |
1 (1.00) |
0.8 (1.00) |
0.15 (0.749) |
0.488 (0.953) |
0.851 (1.00) |
0.812 (1.00) |
0.151 (0.749) |
0.103 (0.694) |
0.963 (1.00) |
0.00574 (0.416) |
0.00323 (0.378) |
0.349 (0.906) |
0.394 (0.921) |
0.0166 (0.452) |
0.047 (0.557) |
0.666 (0.981) |
0.596 (0.969) |
0.681 (0.981) |
0.063 (0.637) |
0.987 (1.00) |
0.0365 (0.53) |
del 6q26 | 100 (34%) | 195 |
0.106 (0.694) |
0.65 (0.976) |
0.789 (1) |
0.604 (0.969) |
1 (1.00) |
1 (1.00) |
0.303 (0.881) |
0.407 (0.921) |
0.384 (0.921) |
0.245 (0.857) |
0.342 (0.902) |
0.514 (0.953) |
0.555 (0.964) |
0.0782 (0.663) |
0.125 (0.712) |
0.407 (0.921) |
0.692 (0.982) |
0.969 (1.00) |
0.536 (0.957) |
0.625 (0.969) |
0.417 (0.93) |
0.15 (0.749) |
0.532 (0.954) |
0.475 (0.949) |
0.967 (1.00) |
0.861 (1.00) |
0.282 (0.866) |
0.598 (0.969) |
0.384 (0.921) |
0.24 (0.856) |
0.855 (1.00) |
0.000747 (0.229) |
0.689 (0.981) |
0.0327 (0.524) |
0.596 (0.969) |
0.476 (0.949) |
0.089 (0.683) |
0.591 (0.969) |
0.367 (0.916) |
del 10q23 31 | 86 (29%) | 209 |
0.379 (0.921) |
0.000904 (0.247) |
0.355 (0.907) |
0.271 (0.862) |
0.706 (0.985) |
0.291 (0.871) |
0.981 (1.00) |
0.949 (1.00) |
0.0998 (0.692) |
0.0167 (0.452) |
1 (1.00) |
0.369 (0.917) |
0.129 (0.712) |
0.00889 (0.444) |
0.266 (0.857) |
0.949 (1.00) |
0.102 (0.692) |
0.127 (0.712) |
1 (1.00) |
0.0817 (0.667) |
0.842 (1.00) |
0.701 (0.985) |
0.0103 (0.444) |
0.815 (1.00) |
0.698 (0.984) |
0.0206 (0.452) |
0.0197 (0.452) |
0.198 (0.796) |
0.0998 (0.692) |
0.242 (0.857) |
0.0909 (0.687) |
0.016 (0.452) |
0.524 (0.953) |
0.241 (0.857) |
0.767 (0.998) |
1 (1.00) |
0.526 (0.953) |
0.00121 (0.284) |
0.4 (0.921) |
del 16q11 2 | 53 (18%) | 242 |
0.823 (1.00) |
0.406 (0.921) |
0.842 (1.00) |
0.0156 (0.452) |
1 (1.00) |
0.155 (0.749) |
2e-05 (0.0246) |
0.265 (0.857) |
0.0762 (0.663) |
0.402 (0.921) |
0.771 (0.998) |
0.894 (1.00) |
1 (1.00) |
0.493 (0.953) |
0.491 (0.953) |
0.265 (0.857) |
0.313 (0.89) |
0.22 (0.828) |
1 (1.00) |
0.305 (0.881) |
0.888 (1.00) |
0.518 (0.953) |
0.591 (0.969) |
0.962 (1.00) |
0.0865 (0.673) |
0.82 (1.00) |
0.117 (0.707) |
0.402 (0.921) |
0.0762 (0.663) |
0.761 (0.998) |
0.0717 (0.661) |
0.743 (0.994) |
0.796 (1.00) |
0.504 (0.953) |
0.113 (0.705) |
1 (1.00) |
0.342 (0.902) |
0.447 (0.948) |
|
del 16q23 1 | 55 (19%) | 240 |
0.421 (0.934) |
0.245 (0.857) |
0.927 (1.00) |
0.316 (0.891) |
0.686 (0.981) |
1 (1.00) |
5e-05 (0.0409) |
0.265 (0.857) |
0.39 (0.921) |
0.00795 (0.444) |
0.378 (0.921) |
0.5 (0.953) |
0.49 (0.953) |
0.224 (0.84) |
0.616 (0.969) |
0.265 (0.857) |
0.513 (0.953) |
0.983 (1.00) |
0.551 (0.962) |
0.105 (0.694) |
0.888 (1.00) |
0.46 (0.949) |
0.439 (0.943) |
0.0277 (0.503) |
0.318 (0.891) |
1 (1.00) |
0.762 (0.998) |
0.667 (0.981) |
0.39 (0.921) |
0.939 (1.00) |
0.14 (0.735) |
0.428 (0.934) |
0.913 (1.00) |
0.383 (0.921) |
0.519 (0.953) |
1 (1.00) |
0.206 (0.811) |
0.979 (1.00) |
|
del 18q21 2 | 82 (28%) | 213 |
0.681 (0.981) |
0.561 (0.966) |
0.62 (0.969) |
0.355 (0.907) |
0.149 (0.749) |
0.473 (0.949) |
1e-05 (0.0246) |
0.588 (0.969) |
0.0506 (0.561) |
0.908 (1.00) |
0.603 (0.969) |
0.144 (0.747) |
0.288 (0.869) |
0.257 (0.857) |
0.975 (1.00) |
0.588 (0.969) |
0.411 (0.922) |
0.385 (0.921) |
1 (1.00) |
0.0926 (0.687) |
0.126 (0.712) |
0.803 (1.00) |
0.174 (0.774) |
0.854 (1.00) |
0.9 (1.00) |
0.474 (0.949) |
0.664 (0.981) |
0.0494 (0.558) |
0.0506 (0.561) |
0.872 (1.00) |
0.68 (0.981) |
0.0214 (0.452) |
0.627 (0.969) |
0.428 (0.934) |
0.0386 (0.53) |
0.122 (0.712) |
0.514 (0.953) |
0.0699 (0.653) |
|
amp 1p31 3 | 96 (33%) | 199 |
0.332 (0.899) |
0.00423 (0.399) |
0.338 (0.9) |
0.86 (1.00) |
0.497 (0.953) |
0.492 (0.953) |
0.244 (0.857) |
0.193 (0.793) |
0.539 (0.959) |
0.473 (0.949) |
0.102 (0.692) |
0.767 (0.998) |
0.768 (0.998) |
0.879 (1.00) |
0.596 (0.969) |
0.193 (0.793) |
0.475 (0.949) |
0.825 (1.00) |
1 (1.00) |
0.0116 (0.444) |
0.386 (0.921) |
0.875 (1.00) |
0.271 (0.862) |
0.149 (0.749) |
0.93 (1.00) |
0.525 (0.953) |
0.0157 (0.452) |
0.861 (1.00) |
0.539 (0.959) |
0.518 (0.953) |
0.375 (0.921) |
0.501 (0.953) |
0.0425 (0.533) |
0.36 (0.913) |
0.777 (0.999) |
0.786 (1) |
0.464 (0.949) |
0.00355 (0.396) |
0.395 (0.921) |
amp 1q21 3 | 158 (54%) | 137 |
0.542 (0.962) |
0.24 (0.857) |
0.0283 (0.504) |
0.635 (0.97) |
0.182 (0.781) |
0.745 (0.994) |
0.241 (0.857) |
0.722 (0.989) |
0.6 (0.969) |
0.00539 (0.416) |
0.506 (0.953) |
0.172 (0.774) |
0.168 (0.767) |
0.374 (0.921) |
0.723 (0.989) |
0.722 (0.989) |
0.86 (1.00) |
0.597 (0.969) |
0.56 (0.966) |
0.14 (0.735) |
0.482 (0.949) |
0.537 (0.958) |
0.219 (0.828) |
0.962 (1.00) |
0.00536 (0.416) |
0.685 (0.981) |
0.336 (0.899) |
0.62 (0.969) |
0.6 (0.969) |
0.914 (1.00) |
1 (1.00) |
0.733 (0.994) |
0.277 (0.866) |
0.0438 (0.537) |
0.612 (0.969) |
0.344 (0.902) |
0.291 (0.871) |
0.198 (0.796) |
0.334 (0.899) |
amp 1q44 | 152 (52%) | 143 |
0.342 (0.902) |
0.333 (0.899) |
0.0547 (0.582) |
0.522 (0.953) |
0.182 (0.781) |
1 (1.00) |
0.0788 (0.663) |
0.34 (0.902) |
0.31 (0.89) |
0.0245 (0.485) |
0.269 (0.862) |
0.332 (0.899) |
0.408 (0.922) |
0.209 (0.814) |
0.815 (1.00) |
0.34 (0.902) |
0.613 (0.969) |
0.757 (0.998) |
1 (1.00) |
0.735 (0.994) |
0.482 (0.949) |
0.546 (0.962) |
0.767 (0.998) |
0.465 (0.949) |
0.3 (0.881) |
0.882 (1.00) |
0.168 (0.767) |
0.0683 (0.645) |
0.31 (0.89) |
0.837 (1.00) |
0.496 (0.953) |
0.715 (0.987) |
0.363 (0.916) |
0.13 (0.712) |
1 (1.00) |
0.129 (0.712) |
0.807 (1.00) |
0.278 (0.866) |
0.739 (0.994) |
amp 2p24 3 | 79 (27%) | 216 |
0.772 (0.998) |
0.929 (1.00) |
0.616 (0.969) |
0.715 (0.987) |
0.48 (0.949) |
0.363 (0.916) |
0.544 (0.962) |
0.168 (0.767) |
0.476 (0.949) |
0.504 (0.953) |
1 (1.00) |
0.468 (0.949) |
0.536 (0.957) |
0.447 (0.948) |
0.138 (0.729) |
0.168 (0.767) |
0.804 (1.00) |
0.68 (0.981) |
1 (1.00) |
0.412 (0.922) |
0.178 (0.778) |
0.265 (0.857) |
0.409 (0.922) |
0.759 (0.998) |
0.0727 (0.663) |
0.906 (1.00) |
1 (1.00) |
0.706 (0.985) |
0.476 (0.949) |
0.609 (0.969) |
0.844 (1.00) |
0.822 (1.00) |
0.577 (0.969) |
0.665 (0.981) |
0.391 (0.921) |
0.5 (0.953) |
0.014 (0.452) |
0.897 (1.00) |
0.398 (0.921) |
amp 2q33 1 | 41 (14%) | 254 |
0.933 (1.00) |
0.29 (0.871) |
0.873 (1.00) |
0.0793 (0.663) |
1 (1.00) |
0.637 (0.97) |
0.554 (0.963) |
0.788 (1) |
0.0373 (0.53) |
0.311 (0.89) |
0.743 (0.994) |
0.0496 (0.558) |
0.847 (1.00) |
0.834 (1.00) |
0.447 (0.948) |
0.788 (1) |
0.627 (0.969) |
0.0667 (0.645) |
0.459 (0.949) |
0.633 (0.97) |
0.333 (0.899) |
0.684 (0.981) |
0.592 (0.969) |
0.559 (0.966) |
0.0206 (0.452) |
1 (1.00) |
0.594 (0.969) |
0.0478 (0.557) |
0.0373 (0.53) |
0.486 (0.953) |
0.605 (0.969) |
0.128 (0.712) |
0.213 (0.822) |
0.577 (0.969) |
0.411 (0.922) |
0.229 (0.84) |
0.268 (0.861) |
0.723 (0.989) |
|
amp 3q26 31 | 227 (77%) | 68 |
0.957 (1.00) |
0.779 (1) |
0.258 (0.857) |
0.0407 (0.53) |
1 (1.00) |
0.0751 (0.663) |
0.0101 (0.444) |
0.961 (1.00) |
0.013 (0.449) |
0.0154 (0.452) |
0.447 (0.948) |
0.116 (0.705) |
1 (1.00) |
0.811 (1.00) |
0.74 (0.994) |
0.961 (1.00) |
0.744 (0.994) |
0.0498 (0.558) |
0.382 (0.921) |
0.021 (0.452) |
0.147 (0.749) |
0.834 (1.00) |
0.0936 (0.687) |
0.471 (0.949) |
0.0484 (0.557) |
0.251 (0.857) |
0.619 (0.969) |
0.249 (0.857) |
0.013 (0.449) |
0.572 (0.968) |
0.689 (0.981) |
0.551 (0.962) |
1 (1.00) |
0.249 (0.857) |
1 (1.00) |
0.0399 (0.53) |
0.836 (1.00) |
0.89 (1.00) |
|
amp 3q28 | 224 (76%) | 71 |
0.708 (0.985) |
0.802 (1.00) |
0.262 (0.857) |
0.0464 (0.554) |
0.258 (0.857) |
0.334 (0.899) |
0.00721 (0.444) |
0.907 (1.00) |
0.0257 (0.49) |
0.239 (0.853) |
1 (1.00) |
0.174 (0.774) |
0.626 (0.969) |
0.763 (0.998) |
0.74 (0.994) |
0.907 (1.00) |
0.738 (0.994) |
0.0988 (0.692) |
0.459 (0.949) |
0.0353 (0.53) |
0.147 (0.749) |
1 (1.00) |
0.238 (0.853) |
0.596 (0.969) |
0.0484 (0.557) |
0.25 (0.857) |
0.509 (0.953) |
0.706 (0.985) |
0.0257 (0.49) |
0.749 (0.994) |
0.689 (0.981) |
0.338 (0.9) |
0.928 (1.00) |
0.167 (0.767) |
1 (1.00) |
0.0783 (0.663) |
0.745 (0.994) |
0.977 (1.00) |
|
amp 4q12 | 21 (7%) | 274 |
0.287 (0.869) |
0.553 (0.963) |
0.0425 (0.533) |
0.364 (0.916) |
0.519 (0.953) |
1 (1.00) |
0.412 (0.922) |
0.987 (1.00) |
0.827 (1.00) |
0.433 (0.94) |
1 (1.00) |
0.404 (0.921) |
0.782 (1) |
0.0945 (0.691) |
0.0683 (0.645) |
0.987 (1.00) |
0.491 (0.953) |
0.676 (0.981) |
1 (1.00) |
0.39 (0.921) |
0.515 (0.953) |
0.625 (0.969) |
0.282 (0.866) |
0.444 (0.948) |
0.786 (1) |
0.695 (0.983) |
0.676 (0.981) |
0.209 (0.814) |
0.827 (1.00) |
0.846 (1.00) |
0.725 (0.99) |
0.266 (0.857) |
0.0524 (0.567) |
0.77 (0.998) |
0.587 (0.969) |
1 (1.00) |
0.571 (0.968) |
0.572 (0.968) |
0.0743 (0.663) |
amp 5p15 33 | 138 (47%) | 157 |
0.901 (1.00) |
0.618 (0.969) |
0.176 (0.776) |
1 (1.00) |
0.0949 (0.692) |
0.148 (0.749) |
0.00991 (0.444) |
0.549 (0.962) |
0.894 (1.00) |
0.699 (0.984) |
0.267 (0.857) |
0.981 (1.00) |
0.68 (0.981) |
0.0407 (0.53) |
0.971 (1.00) |
0.549 (0.962) |
0.621 (0.969) |
0.446 (0.948) |
0.56 (0.966) |
0.205 (0.808) |
0.583 (0.969) |
0.872 (1.00) |
0.0102 (0.444) |
0.0896 (0.684) |
0.525 (0.953) |
0.369 (0.917) |
0.659 (0.981) |
0.495 (0.953) |
0.894 (1.00) |
0.114 (0.705) |
0.125 (0.712) |
0.394 (0.921) |
0.786 (1) |
0.946 (1.00) |
1 (1.00) |
0.02 (0.452) |
0.665 (0.981) |
0.709 (0.985) |
0.011 (0.444) |
amp 6p21 33 | 82 (28%) | 213 |
0.338 (0.9) |
0.866 (1.00) |
0.91 (1.00) |
0.477 (0.949) |
1 (1.00) |
0.724 (0.989) |
0.367 (0.916) |
0.155 (0.749) |
0.551 (0.962) |
0.788 (1) |
0.802 (1.00) |
0.506 (0.953) |
0.0485 (0.557) |
0.0885 (0.683) |
0.944 (1.00) |
0.155 (0.749) |
0.501 (0.953) |
0.361 (0.914) |
1 (1.00) |
0.327 (0.897) |
0.843 (1.00) |
0.619 (0.969) |
0.354 (0.907) |
1 (1.00) |
0.104 (0.694) |
1 (1.00) |
0.383 (0.921) |
0.568 (0.968) |
0.551 (0.962) |
0.693 (0.982) |
0.846 (1.00) |
0.121 (0.712) |
0.23 (0.84) |
0.48 (0.949) |
0.234 (0.848) |
0.3 (0.881) |
0.562 (0.966) |
0.806 (1.00) |
0.443 (0.948) |
amp 7p11 2 | 52 (18%) | 243 |
0.111 (0.705) |
0.92 (1.00) |
0.0169 (0.452) |
0.17 (0.77) |
0.179 (0.778) |
0.139 (0.732) |
0.403 (0.921) |
0.0375 (0.53) |
0.0787 (0.663) |
0.528 (0.953) |
1 (1.00) |
0.23 (0.84) |
0.012 (0.445) |
0.123 (0.712) |
0.489 (0.953) |
0.0375 (0.53) |
0.397 (0.921) |
0.345 (0.903) |
0.188 (0.79) |
0.354 (0.907) |
0.934 (1.00) |
0.148 (0.749) |
0.391 (0.921) |
0.596 (0.969) |
0.947 (1.00) |
0.126 (0.712) |
0.851 (1.00) |
0.0364 (0.53) |
0.0787 (0.663) |
0.788 (1) |
0.513 (0.953) |
0.193 (0.793) |
1 (1.00) |
0.885 (1.00) |
1 (1.00) |
1 (1.00) |
0.966 (1.00) |
0.0173 (0.452) |
|
amp 8q24 21 | 127 (43%) | 168 |
0.515 (0.953) |
0.591 (0.969) |
0.0664 (0.645) |
0.42 (0.934) |
0.32 (0.891) |
0.414 (0.926) |
0.231 (0.84) |
0.349 (0.906) |
0.47 (0.949) |
0.822 (1.00) |
1 (1.00) |
0.898 (1.00) |
0.327 (0.897) |
0.194 (0.793) |
0.257 (0.857) |
0.349 (0.906) |
0.715 (0.987) |
0.52 (0.953) |
0.543 (0.962) |
0.65 (0.976) |
0.582 (0.969) |
0.893 (1.00) |
0.721 (0.989) |
0.666 (0.981) |
0.48 (0.949) |
0.301 (0.881) |
0.835 (1.00) |
0.389 (0.921) |
0.47 (0.949) |
0.15 (0.749) |
0.865 (1.00) |
0.595 (0.969) |
0.291 (0.871) |
0.895 (1.00) |
0.194 (0.793) |
0.496 (0.953) |
0.961 (1.00) |
0.593 (0.969) |
0.182 (0.781) |
amp 9p24 1 | 63 (21%) | 232 |
0.237 (0.852) |
0.157 (0.749) |
0.189 (0.79) |
0.00505 (0.416) |
0.684 (0.981) |
0.327 (0.897) |
0.76 (0.998) |
0.0828 (0.667) |
0.0111 (0.444) |
0.0423 (0.533) |
0.771 (0.998) |
0.125 (0.712) |
0.23 (0.84) |
0.35 (0.906) |
0.394 (0.921) |
0.0828 (0.667) |
0.349 (0.906) |
0.548 (0.962) |
1 (1.00) |
0.423 (0.934) |
0.674 (0.981) |
0.112 (0.705) |
0.0545 (0.582) |
0.235 (0.848) |
0.99 (1.00) |
0.365 (0.916) |
0.577 (0.969) |
0.228 (0.84) |
0.0111 (0.444) |
0.185 (0.789) |
0.136 (0.724) |
0.011 (0.444) |
0.16 (0.757) |
0.459 (0.949) |
0.734 (0.994) |
0.267 (0.857) |
0.85 (1.00) |
0.14 (0.735) |
0.249 (0.857) |
amp 11p12 | 23 (8%) | 272 |
0.615 (0.969) |
0.027 (0.502) |
0.26 (0.857) |
0.312 (0.89) |
0.563 (0.966) |
0.399 (0.921) |
0.635 (0.97) |
0.261 (0.857) |
0.0389 (0.53) |
0.299 (0.881) |
0.0459 (0.551) |
0.0754 (0.663) |
0.324 (0.894) |
0.261 (0.857) |
0.261 (0.857) |
0.23 (0.84) |
0.679 (0.981) |
0.459 (0.949) |
0.102 (0.692) |
0.515 (0.953) |
0.426 (0.934) |
0.627 (0.969) |
0.322 (0.892) |
0.197 (0.796) |
0.598 (0.969) |
0.32 (0.891) |
0.0389 (0.53) |
0.971 (1.00) |
0.284 (0.866) |
0.5 (0.953) |
0.188 (0.79) |
0.427 (0.934) |
1 (1.00) |
0.346 (0.903) |
0.659 (0.981) |
0.0248 (0.486) |
0.804 (1.00) |
||
amp 11q13 3 | 41 (14%) | 254 |
0.988 (1.00) |
0.344 (0.902) |
0.944 (1.00) |
0.452 (0.949) |
0.614 (0.969) |
0.809 (1.00) |
0.619 (0.969) |
0.0373 (0.53) |
0.219 (0.828) |
0.422 (0.934) |
0.319 (0.891) |
0.107 (0.694) |
0.692 (0.982) |
0.0143 (0.452) |
1 (1.00) |
0.0373 (0.53) |
0.423 (0.934) |
0.207 (0.811) |
1 (1.00) |
0.814 (1.00) |
0.333 (0.899) |
0.755 (0.998) |
0.813 (1.00) |
0.663 (0.981) |
0.63 (0.969) |
1 (1.00) |
0.634 (0.97) |
0.453 (0.949) |
0.219 (0.828) |
0.388 (0.921) |
0.466 (0.949) |
0.181 (0.781) |
0.547 (0.962) |
0.87 (1.00) |
0.69 (0.981) |
0.424 (0.934) |
0.0677 (0.645) |
0.324 (0.894) |
0.392 (0.921) |
amp 13q22 1 | 65 (22%) | 230 |
0.387 (0.921) |
0.447 (0.948) |
0.127 (0.712) |
0.696 (0.983) |
0.115 (0.705) |
0.334 (0.899) |
0.706 (0.985) |
0.354 (0.907) |
0.1 (0.692) |
0.726 (0.99) |
0.0302 (0.51) |
0.634 (0.97) |
0.0991 (0.692) |
0.763 (0.998) |
0.913 (1.00) |
0.354 (0.907) |
0.384 (0.921) |
0.0929 (0.687) |
0.53 (0.953) |
0.857 (1.00) |
0.683 (0.981) |
0.514 (0.953) |
0.609 (0.969) |
0.143 (0.745) |
0.927 (1.00) |
0.426 (0.934) |
0.915 (1.00) |
0.0729 (0.663) |
0.1 (0.692) |
0.48 (0.949) |
0.671 (0.981) |
0.455 (0.949) |
0.315 (0.89) |
0.516 (0.953) |
0.516 (0.953) |
0.448 (0.948) |
0.494 (0.953) |
0.104 (0.694) |
|
amp 13q34 | 69 (23%) | 226 |
0.398 (0.921) |
0.882 (1.00) |
0.973 (1.00) |
1 (1.00) |
1 (1.00) |
0.716 (0.987) |
0.74 (0.994) |
0.94 (1.00) |
0.48 (0.949) |
0.733 (0.994) |
0.297 (0.878) |
0.974 (1.00) |
0.336 (0.899) |
0.217 (0.828) |
0.211 (0.815) |
0.94 (1.00) |
0.0929 (0.687) |
0.629 (0.969) |
0.0452 (0.547) |
0.831 (1.00) |
0.54 (0.96) |
0.46 (0.949) |
0.644 (0.974) |
0.747 (0.994) |
0.0344 (0.529) |
0.606 (0.969) |
0.624 (0.969) |
0.154 (0.749) |
0.48 (0.949) |
0.687 (0.981) |
0.156 (0.749) |
0.473 (0.949) |
1 (1.00) |
0.455 (0.949) |
0.186 (0.79) |
0.201 (0.8) |
0.936 (1.00) |
0.631 (0.969) |
|
amp 15q26 1 | 76 (26%) | 219 |
0.597 (0.969) |
0.0313 (0.515) |
0.115 (0.705) |
0.463 (0.949) |
0.114 (0.705) |
0.269 (0.862) |
0.132 (0.715) |
0.86 (1.00) |
0.82 (1.00) |
0.222 (0.835) |
0.622 (0.969) |
0.857 (1.00) |
0.637 (0.97) |
0.201 (0.8) |
0.296 (0.877) |
0.86 (1.00) |
0.282 (0.866) |
0.623 (0.969) |
1 (1.00) |
0.0363 (0.53) |
0.801 (1.00) |
0.652 (0.976) |
0.0484 (0.557) |
0.151 (0.749) |
0.372 (0.921) |
0.173 (0.774) |
0.249 (0.857) |
0.701 (0.985) |
0.82 (1.00) |
0.889 (1.00) |
1 (1.00) |
0.721 (0.989) |
0.0692 (0.649) |
0.264 (0.857) |
0.552 (0.962) |
1 (1.00) |
0.193 (0.793) |
0.026 (0.492) |
0.504 (0.953) |
amp 16p13 13 | 65 (22%) | 230 |
0.547 (0.962) |
0.427 (0.934) |
0.118 (0.707) |
0.252 (0.857) |
0.69 (0.981) |
0.692 (0.982) |
0.997 (1.00) |
0.313 (0.89) |
0.0847 (0.667) |
0.293 (0.872) |
0.771 (0.998) |
0.394 (0.921) |
0.234 (0.848) |
0.88 (1.00) |
0.166 (0.767) |
0.313 (0.89) |
0.447 (0.948) |
0.531 (0.953) |
1 (1.00) |
0.0148 (0.452) |
0.683 (0.981) |
0.597 (0.969) |
0.0216 (0.452) |
0.701 (0.985) |
0.0215 (0.452) |
0.65 (0.976) |
0.333 (0.899) |
0.561 (0.966) |
0.0847 (0.667) |
0.517 (0.953) |
1 (1.00) |
0.303 (0.881) |
0.193 (0.793) |
0.508 (0.953) |
0.351 (0.906) |
0.255 (0.857) |
0.469 (0.949) |
0.745 (0.994) |
|
amp 17q12 | 55 (19%) | 240 |
1 (1.00) |
0.707 (0.985) |
0.244 (0.857) |
0.661 (0.981) |
1 (1.00) |
0.845 (1.00) |
0.11 (0.705) |
0.19 (0.79) |
0.315 (0.89) |
0.853 (1.00) |
0.386 (0.921) |
0.575 (0.969) |
0.49 (0.953) |
0.136 (0.724) |
0.156 (0.749) |
0.19 (0.79) |
0.317 (0.891) |
0.668 (0.981) |
1 (1.00) |
0.0822 (0.667) |
0.261 (0.857) |
0.256 (0.857) |
0.261 (0.857) |
0.269 (0.862) |
0.421 (0.934) |
0.818 (1.00) |
0.98 (1.00) |
0.663 (0.981) |
0.315 (0.89) |
0.736 (0.994) |
0.466 (0.949) |
0.672 (0.981) |
0.91 (1.00) |
0.0814 (0.667) |
1 (1.00) |
1 (1.00) |
0.396 (0.921) |
0.75 (0.994) |
0.847 (1.00) |
amp 17q25 1 | 74 (25%) | 221 |
0.76 (0.998) |
0.819 (1.00) |
0.155 (0.749) |
0.263 (0.857) |
0.258 (0.857) |
1 (1.00) |
0.0847 (0.667) |
0.21 (0.815) |
0.0609 (0.621) |
0.583 (0.969) |
0.325 (0.895) |
0.36 (0.913) |
0.527 (0.953) |
0.0854 (0.67) |
0.828 (1.00) |
0.21 (0.815) |
0.331 (0.899) |
0.256 (0.857) |
1 (1.00) |
0.177 (0.778) |
0.166 (0.767) |
0.844 (1.00) |
0.181 (0.781) |
0.35 (0.906) |
0.429 (0.936) |
1 (1.00) |
0.858 (1.00) |
0.0796 (0.663) |
0.0609 (0.621) |
0.397 (0.921) |
0.105 (0.694) |
0.903 (1.00) |
0.396 (0.921) |
0.482 (0.949) |
0.774 (0.998) |
1 (1.00) |
0.396 (0.921) |
0.877 (1.00) |
0.225 (0.84) |
amp 19p13 3 | 39 (13%) | 256 |
0.125 (0.712) |
0.338 (0.9) |
0.367 (0.916) |
0.36 (0.913) |
0.596 (0.969) |
0.814 (1.00) |
0.901 (1.00) |
0.585 (0.969) |
0.0834 (0.667) |
0.844 (1.00) |
1 (1.00) |
0.506 (0.953) |
0.681 (0.981) |
0.865 (1.00) |
0.586 (0.969) |
0.585 (0.969) |
0.262 (0.857) |
0.0407 (0.53) |
1 (1.00) |
0.32 (0.892) |
0.816 (1.00) |
0.278 (0.866) |
0.0286 (0.504) |
0.0818 (0.667) |
0.703 (0.985) |
1 (1.00) |
0.7 (0.985) |
0.1 (0.692) |
0.0834 (0.667) |
0.52 (0.953) |
0.0205 (0.452) |
0.891 (1.00) |
0.198 (0.796) |
0.0537 (0.576) |
1 (1.00) |
1 (1.00) |
0.659 (0.981) |
0.288 (0.869) |
0.217 (0.828) |
amp 19p13 2 | 43 (15%) | 252 |
0.0266 (0.5) |
0.53 (0.953) |
0.541 (0.962) |
0.532 (0.954) |
1 (1.00) |
0.664 (0.981) |
0.591 (0.969) |
0.863 (1.00) |
0.464 (0.949) |
0.589 (0.969) |
0.744 (0.994) |
0.972 (1.00) |
0.174 (0.774) |
0.874 (1.00) |
0.382 (0.921) |
0.863 (1.00) |
0.194 (0.793) |
0.0487 (0.557) |
1 (1.00) |
0.609 (0.969) |
0.816 (1.00) |
0.204 (0.808) |
0.164 (0.767) |
0.652 (0.976) |
0.166 (0.767) |
1 (1.00) |
0.567 (0.968) |
0.811 (1.00) |
0.464 (0.949) |
0.228 (0.84) |
0.00151 (0.286) |
0.352 (0.907) |
0.533 (0.954) |
0.128 (0.712) |
0.12 (0.711) |
0.638 (0.971) |
0.571 (0.968) |
0.466 (0.949) |
0.781 (1) |
amp 19q13 13 | 93 (32%) | 202 |
0.612 (0.969) |
0.119 (0.709) |
0.0304 (0.51) |
0.0846 (0.667) |
0.277 (0.866) |
0.724 (0.989) |
0.516 (0.953) |
0.756 (0.998) |
0.106 (0.694) |
0.828 (1.00) |
0.469 (0.949) |
0.871 (1.00) |
0.551 (0.962) |
0.774 (0.998) |
0.806 (1.00) |
0.756 (0.998) |
0.019 (0.452) |
0.514 (0.953) |
0.56 (0.966) |
0.124 (0.712) |
0.757 (0.998) |
0.0511 (0.563) |
0.0439 (0.537) |
0.704 (0.985) |
0.135 (0.724) |
0.13 (0.712) |
0.301 (0.881) |
0.281 (0.866) |
0.106 (0.694) |
0.331 (0.899) |
0.144 (0.747) |
0.475 (0.949) |
0.602 (0.969) |
0.606 (0.969) |
0.253 (0.857) |
0.844 (1.00) |
0.753 (0.997) |
0.114 (0.705) |
0.167 (0.767) |
amp 20q11 21 | 135 (46%) | 160 |
0.652 (0.976) |
0.0273 (0.503) |
0.011 (0.444) |
0.336 (0.899) |
0.341 (0.902) |
0.748 (0.994) |
0.652 (0.976) |
0.918 (1.00) |
0.208 (0.813) |
0.0305 (0.51) |
0.115 (0.705) |
0.153 (0.749) |
0.584 (0.969) |
0.64 (0.971) |
0.678 (0.981) |
0.918 (1.00) |
0.26 (0.857) |
0.674 (0.981) |
0.56 (0.966) |
0.0681 (0.645) |
0.726 (0.99) |
0.967 (1.00) |
0.166 (0.767) |
0.791 (1.00) |
0.526 (0.953) |
0.118 (0.707) |
0.296 (0.877) |
0.739 (0.994) |
0.208 (0.813) |
0.581 (0.969) |
0.388 (0.921) |
0.294 (0.872) |
0.787 (1) |
0.407 (0.921) |
0.609 (0.969) |
0.411 (0.922) |
0.493 (0.953) |
0.0198 (0.452) |
0.551 (0.962) |
amp 21q22 13 | 48 (16%) | 247 |
0.282 (0.866) |
0.163 (0.767) |
0.272 (0.865) |
1 (1.00) |
1 (1.00) |
0.829 (1.00) |
0.522 (0.953) |
0.748 (0.994) |
0.776 (0.998) |
0.956 (1.00) |
1 (1.00) |
0.828 (1.00) |
0.26 (0.857) |
0.242 (0.857) |
0.53 (0.953) |
0.748 (0.994) |
0.514 (0.953) |
0.892 (1.00) |
0.459 (0.949) |
0.998 (1.00) |
0.328 (0.899) |
0.814 (1.00) |
0.982 (1.00) |
0.404 (0.921) |
0.947 (1.00) |
0.196 (0.796) |
0.396 (0.921) |
1 (1.00) |
0.776 (0.998) |
0.637 (0.97) |
0.0393 (0.53) |
0.945 (1.00) |
0.438 (0.943) |
0.472 (0.949) |
0.686 (0.981) |
1 (1.00) |
0.96 (1.00) |
0.178 (0.778) |
0.234 (0.848) |
amp xq28 | 75 (25%) | 220 |
0.0578 (0.602) |
0.343 (0.902) |
0.12 (0.71) |
0.273 (0.866) |
0.448 (0.948) |
0.0391 (0.53) |
0.089 (0.683) |
0.523 (0.953) |
0.571 (0.968) |
0.12 (0.711) |
0.789 (1) |
0.879 (1.00) |
0.746 (0.994) |
0.427 (0.934) |
0.107 (0.694) |
0.523 (0.953) |
0.712 (0.987) |
0.425 (0.934) |
0.459 (0.949) |
0.299 (0.881) |
0.8 (1.00) |
0.448 (0.948) |
0.351 (0.906) |
0.895 (1.00) |
0.756 (0.998) |
0.623 (0.969) |
0.628 (0.969) |
1 (1.00) |
0.571 (0.968) |
0.824 (1.00) |
0.544 (0.962) |
0.0738 (0.663) |
0.524 (0.953) |
0.276 (0.866) |
0.553 (0.963) |
1 (1.00) |
0.955 (1.00) |
0.308 (0.885) |
0.672 (0.981) |
del 1p36 23 | 40 (14%) | 255 |
0.631 (0.969) |
0.0644 (0.639) |
0.571 (0.968) |
0.797 (1.00) |
0.08 (0.664) |
0.314 (0.89) |
0.00727 (0.444) |
0.0174 (0.452) |
0.894 (1.00) |
0.905 (1.00) |
1 (1.00) |
0.686 (0.981) |
0.236 (0.849) |
0.664 (0.981) |
0.864 (1.00) |
0.0174 (0.452) |
0.621 (0.969) |
0.366 (0.916) |
0.53 (0.953) |
0.796 (1.00) |
0.874 (1.00) |
0.387 (0.921) |
0.474 (0.949) |
0.426 (0.934) |
0.684 (0.981) |
0.689 (0.981) |
0.397 (0.921) |
0.8 (1.00) |
0.894 (1.00) |
0.273 (0.865) |
0.357 (0.911) |
0.28 (0.866) |
0.764 (0.998) |
0.326 (0.896) |
0.463 (0.949) |
0.255 (0.857) |
0.0716 (0.661) |
0.506 (0.953) |
|
del 1p13 2 | 34 (12%) | 261 |
0.0566 (0.594) |
0.97 (1.00) |
0.729 (0.993) |
0.281 (0.866) |
0.115 (0.705) |
0.808 (1.00) |
0.785 (1) |
0.696 (0.983) |
0.577 (0.969) |
0.76 (0.998) |
1 (1.00) |
0.937 (1.00) |
0.0935 (0.687) |
0.546 (0.962) |
0.696 (0.983) |
0.0433 (0.534) |
0.247 (0.857) |
1 (1.00) |
0.0782 (0.663) |
0.483 (0.949) |
0.0755 (0.663) |
0.551 (0.962) |
0.0726 (0.663) |
0.898 (1.00) |
1 (1.00) |
0.596 (0.969) |
0.527 (0.953) |
0.577 (0.969) |
0.919 (1.00) |
0.0561 (0.594) |
0.0773 (0.663) |
0.548 (0.962) |
0.457 (0.949) |
1 (1.00) |
0.175 (0.776) |
0.995 (1.00) |
0.454 (0.949) |
||
del 2q22 1 | 65 (22%) | 230 |
0.819 (1.00) |
0.566 (0.967) |
0.41 (0.922) |
0.85 (1.00) |
1 (1.00) |
0.849 (1.00) |
0.43 (0.937) |
0.303 (0.881) |
0.611 (0.969) |
0.198 (0.796) |
0.592 (0.969) |
0.704 (0.985) |
1 (1.00) |
0.264 (0.857) |
0.332 (0.899) |
0.303 (0.881) |
0.455 (0.949) |
0.23 (0.84) |
0.551 (0.962) |
0.989 (1.00) |
0.888 (1.00) |
0.673 (0.981) |
0.293 (0.872) |
0.0581 (0.602) |
0.816 (1.00) |
0.45 (0.949) |
0.256 (0.857) |
0.424 (0.934) |
0.611 (0.969) |
0.118 (0.707) |
0.844 (1.00) |
0.378 (0.921) |
0.423 (0.934) |
0.331 (0.899) |
0.021 (0.452) |
1 (1.00) |
0.225 (0.84) |
0.522 (0.953) |
0.498 (0.953) |
del 2q37 1 | 129 (44%) | 166 |
0.996 (1.00) |
0.0104 (0.444) |
0.482 (0.949) |
0.521 (0.953) |
0.182 (0.781) |
0.744 (0.994) |
0.0519 (0.567) |
0.592 (0.969) |
0.47 (0.949) |
0.546 (0.962) |
0.502 (0.953) |
0.338 (0.9) |
0.489 (0.953) |
0.982 (1.00) |
0.0141 (0.452) |
0.592 (0.969) |
0.104 (0.694) |
0.399 (0.921) |
0.56 (0.966) |
0.911 (1.00) |
0.19 (0.792) |
0.646 (0.975) |
0.882 (1.00) |
0.344 (0.902) |
0.973 (1.00) |
0.306 (0.882) |
0.277 (0.866) |
1 (1.00) |
0.47 (0.949) |
0.00432 (0.399) |
0.612 (0.969) |
0.989 (1.00) |
0.744 (0.994) |
0.852 (1.00) |
0.3 (0.881) |
0.683 (0.981) |
0.96 (1.00) |
0.0158 (0.452) |
0.712 (0.987) |
del 4q21 3 | 103 (35%) | 192 |
0.114 (0.705) |
0.966 (1.00) |
0.27 (0.862) |
0.0101 (0.444) |
0.0937 (0.687) |
0.0188 (0.452) |
0.0293 (0.504) |
0.63 (0.969) |
0.00863 (0.444) |
0.116 (0.705) |
1 (1.00) |
0.00439 (0.399) |
0.148 (0.749) |
0.0107 (0.444) |
0.287 (0.869) |
0.63 (0.969) |
0.121 (0.711) |
0.798 (1.00) |
1 (1.00) |
0.673 (0.981) |
0.616 (0.969) |
0.446 (0.948) |
0.247 (0.857) |
0.365 (0.916) |
0.641 (0.972) |
0.228 (0.84) |
0.928 (1.00) |
0.479 (0.949) |
0.00863 (0.444) |
0.351 (0.906) |
0.599 (0.969) |
0.247 (0.857) |
0.744 (0.994) |
0.705 (0.985) |
0.149 (0.749) |
0.694 (0.983) |
0.157 (0.749) |
0.981 (1.00) |
0.363 (0.916) |
del 4q22 1 | 100 (34%) | 195 |
0.354 (0.907) |
0.867 (1.00) |
0.23 (0.84) |
0.0846 (0.667) |
0.304 (0.881) |
0.00383 (0.399) |
0.0386 (0.53) |
0.61 (0.969) |
0.0417 (0.533) |
0.251 (0.857) |
0.636 (0.97) |
0.0288 (0.504) |
0.387 (0.921) |
0.00132 (0.284) |
0.208 (0.813) |
0.61 (0.969) |
0.457 (0.949) |
0.714 (0.987) |
0.543 (0.962) |
0.893 (1.00) |
0.651 (0.976) |
0.717 (0.988) |
0.369 (0.917) |
0.778 (0.999) |
0.585 (0.969) |
0.109 (0.704) |
0.943 (1.00) |
0.274 (0.866) |
0.0417 (0.533) |
0.485 (0.952) |
0.858 (1.00) |
0.287 (0.869) |
0.591 (0.969) |
0.855 (1.00) |
0.391 (0.921) |
0.826 (1.00) |
0.157 (0.749) |
0.885 (1.00) |
0.538 (0.959) |
del 4q35 2 | 114 (39%) | 181 |
0.569 (0.968) |
0.32 (0.891) |
0.291 (0.871) |
0.319 (0.891) |
1 (1.00) |
0.0679 (0.645) |
0.0751 (0.663) |
0.175 (0.776) |
0.304 (0.881) |
0.737 (0.994) |
0.179 (0.779) |
0.205 (0.808) |
1 (1.00) |
0.0191 (0.452) |
0.305 (0.881) |
0.175 (0.776) |
0.628 (0.969) |
0.219 (0.828) |
0.56 (0.966) |
0.656 (0.98) |
0.0618 (0.628) |
0.27 (0.862) |
0.703 (0.985) |
0.598 (0.969) |
0.805 (1.00) |
0.398 (0.921) |
0.403 (0.921) |
0.605 (0.969) |
0.304 (0.881) |
0.564 (0.967) |
0.392 (0.921) |
0.395 (0.921) |
0.406 (0.921) |
0.616 (0.969) |
0.786 (1) |
0.687 (0.981) |
0.393 (0.921) |
0.326 (0.896) |
0.512 (0.953) |
del 5q12 1 | 76 (26%) | 219 |
0.0789 (0.663) |
0.963 (1.00) |
0.498 (0.953) |
0.263 (0.857) |
1 (1.00) |
0.845 (1.00) |
0.528 (0.953) |
0.13 (0.712) |
0.0667 (0.645) |
0.833 (1.00) |
0.447 (0.948) |
0.0401 (0.53) |
0.159 (0.754) |
0.513 (0.953) |
0.0487 (0.557) |
0.13 (0.712) |
0.46 (0.949) |
0.402 (0.921) |
1 (1.00) |
0.466 (0.949) |
0.155 (0.749) |
0.189 (0.79) |
0.775 (0.998) |
0.0913 (0.687) |
0.959 (1.00) |
0.63 (0.969) |
0.576 (0.969) |
0.182 (0.781) |
0.0667 (0.645) |
0.848 (1.00) |
0.704 (0.985) |
0.245 (0.857) |
0.928 (1.00) |
0.768 (0.998) |
1 (1.00) |
0.255 (0.857) |
0.0307 (0.51) |
0.93 (1.00) |
0.179 (0.778) |
del 5q35 2 | 71 (24%) | 224 |
0.737 (0.994) |
0.536 (0.957) |
0.136 (0.724) |
0.709 (0.985) |
0.283 (0.866) |
0.692 (0.982) |
0.321 (0.892) |
0.367 (0.916) |
0.0318 (0.515) |
0.885 (1.00) |
1 (1.00) |
0.305 (0.881) |
0.631 (0.969) |
0.169 (0.768) |
0.41 (0.922) |
0.367 (0.916) |
0.466 (0.949) |
0.924 (1.00) |
1 (1.00) |
0.871 (1.00) |
0.166 (0.767) |
0.278 (0.866) |
0.629 (0.969) |
0.0477 (0.557) |
0.53 (0.953) |
0.459 (0.949) |
1 (1.00) |
0.131 (0.713) |
0.0318 (0.515) |
0.91 (1.00) |
0.186 (0.79) |
0.745 (0.994) |
0.82 (1.00) |
0.385 (0.921) |
0.776 (0.998) |
0.315 (0.89) |
0.209 (0.814) |
0.567 (0.968) |
0.403 (0.921) |
del 6p24 2 | 46 (16%) | 249 |
0.681 (0.981) |
0.848 (1.00) |
0.787 (1) |
0.277 (0.866) |
0.686 (0.981) |
0.656 (0.98) |
0.126 (0.712) |
0.394 (0.921) |
0.136 (0.724) |
0.508 (0.953) |
0.523 (0.953) |
0.294 (0.872) |
0.565 (0.967) |
0.857 (1.00) |
0.106 (0.694) |
0.394 (0.921) |
0.925 (1.00) |
1 (1.00) |
1 (1.00) |
0.467 (0.949) |
0.454 (0.949) |
0.111 (0.705) |
0.607 (0.969) |
0.331 (0.899) |
0.819 (1.00) |
0.678 (0.981) |
0.281 (0.866) |
0.383 (0.921) |
0.136 (0.724) |
0.194 (0.793) |
0.51 (0.953) |
0.224 (0.84) |
0.386 (0.921) |
0.474 (0.949) |
0.519 (0.953) |
0.713 (0.987) |
0.0376 (0.53) |
0.808 (1.00) |
0.984 (1.00) |
del 7q34 | 60 (20%) | 235 |
0.187 (0.79) |
0.0863 (0.673) |
0.557 (0.966) |
0.219 (0.828) |
1 (1.00) |
0.68 (0.981) |
0.775 (0.998) |
0.112 (0.705) |
0.0217 (0.452) |
0.933 (1.00) |
0.603 (0.969) |
0.735 (0.994) |
0.242 (0.857) |
0.748 (0.994) |
0.856 (1.00) |
0.112 (0.705) |
0.518 (0.953) |
0.249 (0.857) |
0.583 (0.969) |
0.776 (0.998) |
0.202 (0.804) |
0.776 (0.998) |
0.612 (0.969) |
0.092 (0.687) |
0.287 (0.869) |
0.868 (1.00) |
0.561 (0.966) |
0.216 (0.828) |
0.0217 (0.452) |
0.349 (0.906) |
0.418 (0.931) |
0.72 (0.989) |
0.748 (0.994) |
0.697 (0.984) |
0.755 (0.998) |
0.795 (1.00) |
0.591 (0.969) |
0.077 (0.663) |
0.854 (1.00) |
del 8p23 3 | 104 (35%) | 191 |
0.0042 (0.399) |
0.264 (0.857) |
0.888 (1.00) |
0.502 (0.953) |
0.732 (0.994) |
0.604 (0.969) |
0.936 (1.00) |
0.529 (0.953) |
0.3 (0.881) |
0.79 (1.00) |
1 (1.00) |
0.924 (1.00) |
0.064 (0.639) |
0.438 (0.943) |
0.199 (0.798) |
0.529 (0.953) |
0.345 (0.903) |
0.0338 (0.529) |
1 (1.00) |
0.84 (1.00) |
0.966 (1.00) |
0.164 (0.767) |
0.979 (1.00) |
0.68 (0.981) |
0.986 (1.00) |
0.708 (0.985) |
0.873 (1.00) |
0.153 (0.749) |
0.3 (0.881) |
0.519 (0.953) |
0.215 (0.827) |
0.319 (0.891) |
0.494 (0.953) |
0.748 (0.994) |
0.596 (0.969) |
1 (1.00) |
0.136 (0.724) |
0.23 (0.84) |
0.571 (0.968) |
del 8p23 1 | 97 (33%) | 198 |
0.00743 (0.444) |
0.166 (0.767) |
0.954 (1.00) |
0.498 (0.953) |
0.725 (0.99) |
0.288 (0.869) |
0.781 (1) |
0.318 (0.891) |
0.236 (0.848) |
0.323 (0.893) |
0.812 (1.00) |
0.857 (1.00) |
0.0286 (0.504) |
0.236 (0.848) |
0.0219 (0.452) |
0.318 (0.891) |
0.586 (0.969) |
0.123 (0.712) |
0.56 (0.966) |
0.789 (1) |
0.757 (0.998) |
0.197 (0.796) |
0.968 (1.00) |
1 (1.00) |
0.698 (0.984) |
0.861 (1.00) |
0.838 (1.00) |
0.101 (0.692) |
0.236 (0.848) |
0.433 (0.94) |
0.367 (0.916) |
0.779 (1) |
0.967 (1.00) |
0.776 (0.998) |
0.786 (1) |
1 (1.00) |
0.13 (0.712) |
0.145 (0.748) |
0.441 (0.947) |
del 11p15 1 | 102 (35%) | 193 |
0.41 (0.922) |
0.00308 (0.378) |
0.533 (0.954) |
0.387 (0.921) |
0.494 (0.953) |
0.739 (0.994) |
0.114 (0.705) |
0.229 (0.84) |
0.177 (0.778) |
0.106 (0.694) |
0.648 (0.976) |
0.227 (0.84) |
0.2 (0.798) |
0.0958 (0.692) |
0.516 (0.953) |
0.229 (0.84) |
0.802 (1.00) |
0.327 (0.897) |
0.551 (0.962) |
0.1 (0.692) |
0.0531 (0.572) |
0.512 (0.953) |
0.127 (0.712) |
0.901 (1.00) |
0.0124 (0.449) |
0.518 (0.953) |
0.00814 (0.444) |
0.375 (0.921) |
0.177 (0.778) |
0.499 (0.953) |
0.719 (0.989) |
0.803 (1.00) |
0.0758 (0.663) |
0.13 (0.712) |
1 (1.00) |
0.206 (0.811) |
0.958 (1.00) |
0.00193 (0.338) |
0.166 (0.767) |
del 11q23 3 | 162 (55%) | 133 |
0.938 (1.00) |
0.0145 (0.452) |
0.788 (1) |
0.749 (0.994) |
0.741 (0.994) |
0.871 (1.00) |
0.0122 (0.449) |
0.599 (0.969) |
0.671 (0.981) |
0.2 (0.799) |
0.188 (0.79) |
0.731 (0.994) |
0.406 (0.921) |
0.765 (0.998) |
0.902 (1.00) |
0.599 (0.969) |
0.748 (0.994) |
0.03 (0.51) |
1 (1.00) |
0.151 (0.749) |
0.482 (0.949) |
0.771 (0.998) |
0.393 (0.921) |
0.67 (0.981) |
0.0343 (0.529) |
0.89 (1.00) |
0.0193 (0.452) |
0.134 (0.724) |
0.671 (0.981) |
0.5 (0.953) |
0.864 (1.00) |
0.0382 (0.53) |
0.498 (0.953) |
0.897 (1.00) |
0.437 (0.943) |
0.331 (0.899) |
0.661 (0.981) |
0.0216 (0.452) |
0.00868 (0.444) |
del 11q25 | 160 (54%) | 135 |
0.452 (0.949) |
0.15 (0.749) |
0.628 (0.969) |
0.873 (1.00) |
0.739 (0.994) |
0.871 (1.00) |
0.0192 (0.452) |
0.71 (0.985) |
0.885 (1.00) |
0.179 (0.778) |
0.0753 (0.663) |
0.677 (0.981) |
0.168 (0.767) |
0.684 (0.981) |
0.618 (0.969) |
0.71 (0.985) |
0.61 (0.969) |
0.0564 (0.594) |
1 (1.00) |
0.262 (0.857) |
0.482 (0.949) |
0.771 (0.998) |
0.696 (0.983) |
0.469 (0.949) |
0.0343 (0.529) |
0.89 (1.00) |
0.0637 (0.639) |
0.0671 (0.645) |
0.885 (1.00) |
0.643 (0.974) |
1 (1.00) |
0.0182 (0.452) |
0.839 (1.00) |
0.419 (0.932) |
0.437 (0.943) |
0.339 (0.901) |
0.807 (1.00) |
0.195 (0.793) |
0.0224 (0.458) |
del 13q12 11 | 98 (33%) | 197 |
0.376 (0.921) |
0.954 (1.00) |
0.0792 (0.663) |
0.0796 (0.663) |
0.288 (0.869) |
1 (1.00) |
0.00323 (0.378) |
0.58 (0.969) |
0.0114 (0.444) |
0.0892 (0.683) |
0.345 (0.902) |
0.126 (0.712) |
0.473 (0.949) |
0.0872 (0.676) |
0.664 (0.981) |
0.58 (0.969) |
0.059 (0.606) |
0.109 (0.702) |
1 (1.00) |
0.149 (0.749) |
0.967 (1.00) |
0.583 (0.969) |
0.195 (0.793) |
0.665 (0.981) |
0.252 (0.857) |
0.86 (1.00) |
0.63 (0.969) |
0.288 (0.869) |
0.0114 (0.444) |
0.473 (0.949) |
0.723 (0.989) |
0.0232 (0.47) |
0.641 (0.972) |
0.572 (0.968) |
0.253 (0.857) |
0.261 (0.857) |
0.317 (0.891) |
0.91 (1.00) |
0.01 (0.444) |
del 13q14 2 | 118 (40%) | 177 |
0.277 (0.866) |
0.126 (0.712) |
0.0047 (0.412) |
0.0459 (0.551) |
0.517 (0.953) |
0.25 (0.857) |
0.0195 (0.452) |
0.322 (0.892) |
0.0151 (0.452) |
0.0184 (0.452) |
0.645 (0.975) |
0.95 (1.00) |
0.26 (0.857) |
0.00912 (0.444) |
0.0406 (0.53) |
0.322 (0.892) |
0.0157 (0.452) |
0.0361 (0.53) |
1 (1.00) |
0.033 (0.524) |
0.967 (1.00) |
0.526 (0.953) |
0.00826 (0.444) |
0.473 (0.949) |
0.0366 (0.53) |
0.629 (0.969) |
0.736 (0.994) |
0.385 (0.921) |
0.0151 (0.452) |
0.667 (0.981) |
0.731 (0.994) |
0.0384 (0.53) |
0.824 (1.00) |
0.384 (0.921) |
0.0913 (0.687) |
0.0837 (0.667) |
0.651 (0.976) |
0.0961 (0.692) |
0.0127 (0.449) |
del 14q32 31 | 50 (17%) | 245 |
0.648 (0.976) |
0.102 (0.692) |
0.703 (0.985) |
1 (1.00) |
0.117 (0.707) |
0.654 (0.978) |
0.0985 (0.692) |
0.44 (0.946) |
0.278 (0.866) |
0.632 (0.969) |
0.757 (0.998) |
0.933 (1.00) |
0.563 (0.966) |
0.0132 (0.451) |
0.938 (1.00) |
0.44 (0.946) |
0.0643 (0.639) |
0.956 (1.00) |
1 (1.00) |
0.0813 (0.667) |
0.377 (0.921) |
0.446 (0.948) |
0.289 (0.871) |
0.172 (0.774) |
0.517 (0.953) |
0.927 (1.00) |
0.118 (0.708) |
0.506 (0.953) |
0.278 (0.866) |
0.474 (0.949) |
0.813 (1.00) |
0.525 (0.953) |
0.386 (0.921) |
0.625 (0.969) |
1 (1.00) |
0.343 (0.902) |
0.114 (0.705) |
0.789 (1) |
|
del 15q21 1 | 70 (24%) | 225 |
0.805 (1.00) |
0.0112 (0.444) |
0.216 (0.828) |
0.234 (0.848) |
0.393 (0.921) |
0.13 (0.712) |
0.00564 (0.416) |
0.785 (1) |
0.59 (0.969) |
0.0291 (0.504) |
1 (1.00) |
0.924 (1.00) |
0.873 (1.00) |
0.0118 (0.445) |
0.155 (0.749) |
0.785 (1) |
0.632 (0.969) |
0.715 (0.987) |
1 (1.00) |
0.849 (1.00) |
0.93 (1.00) |
0.0752 (0.663) |
0.314 (0.89) |
0.863 (1.00) |
0.844 (1.00) |
0.887 (1.00) |
0.0574 (0.6) |
0.818 (1.00) |
0.59 (0.969) |
0.432 (0.94) |
0.513 (0.953) |
0.673 (0.981) |
0.373 (0.921) |
0.643 (0.974) |
0.724 (0.989) |
0.292 (0.872) |
0.733 (0.994) |
0.0135 (0.452) |
0.133 (0.718) |
del 17p12 | 109 (37%) | 186 |
0.4 (0.921) |
0.0195 (0.452) |
0.831 (1.00) |
0.604 (0.969) |
1 (1.00) |
0.622 (0.969) |
0.572 (0.968) |
0.526 (0.953) |
0.93 (1.00) |
0.167 (0.767) |
0.646 (0.975) |
0.198 (0.796) |
0.0334 (0.526) |
0.0524 (0.567) |
0.715 (0.987) |
0.526 (0.953) |
0.0507 (0.561) |
0.434 (0.94) |
1 (1.00) |
0.832 (1.00) |
0.46 (0.949) |
0.69 (0.981) |
0.157 (0.749) |
0.0493 (0.558) |
0.632 (0.969) |
0.681 (0.981) |
0.532 (0.954) |
1 (1.00) |
0.93 (1.00) |
0.405 (0.921) |
0.602 (0.969) |
0.621 (0.969) |
0.266 (0.857) |
0.411 (0.922) |
0.787 (1) |
0.689 (0.981) |
0.119 (0.71) |
0.0249 (0.486) |
0.702 (0.985) |
del 17q25 3 | 51 (17%) | 244 |
0.417 (0.93) |
0.703 (0.985) |
0.988 (1.00) |
0.409 (0.922) |
0.649 (0.976) |
0.822 (1.00) |
0.104 (0.694) |
0.245 (0.857) |
0.763 (0.998) |
0.261 (0.857) |
1 (1.00) |
0.492 (0.953) |
0.565 (0.967) |
0.305 (0.881) |
0.343 (0.902) |
0.245 (0.857) |
0.0981 (0.692) |
0.373 (0.921) |
1 (1.00) |
0.948 (1.00) |
0.314 (0.89) |
0.434 (0.94) |
0.805 (1.00) |
0.574 (0.969) |
0.149 (0.749) |
0.822 (1.00) |
0.885 (1.00) |
1 (1.00) |
0.763 (0.998) |
0.259 (0.857) |
0.678 (0.981) |
0.738 (0.994) |
1 (1.00) |
0.156 (0.749) |
0.458 (0.949) |
1 (1.00) |
0.958 (1.00) |
0.523 (0.953) |
0.422 (0.934) |
del 19p13 3 | 105 (36%) | 190 |
0.00266 (0.378) |
0.623 (0.969) |
0.591 (0.969) |
0.864 (1.00) |
0.723 (0.989) |
0.404 (0.921) |
0.315 (0.89) |
0.382 (0.921) |
0.974 (1.00) |
0.167 (0.767) |
0.099 (0.692) |
0.509 (0.953) |
0.00139 (0.284) |
0.116 (0.705) |
0.592 (0.969) |
0.382 (0.921) |
0.995 (1.00) |
0.589 (0.969) |
1 (1.00) |
0.999 (1.00) |
0.101 (0.692) |
0.358 (0.912) |
0.656 (0.98) |
0.127 (0.712) |
0.681 (0.981) |
0.802 (1.00) |
0.622 (0.969) |
0.479 (0.949) |
0.974 (1.00) |
0.556 (0.966) |
0.367 (0.916) |
0.497 (0.953) |
0.968 (1.00) |
0.107 (0.694) |
1 (1.00) |
0.828 (1.00) |
0.082 (0.667) |
0.558 (0.966) |
0.994 (1.00) |
del 19q13 33 | 38 (13%) | 257 |
0.361 (0.914) |
0.199 (0.798) |
0.949 (1.00) |
0.81 (1.00) |
0.614 (0.969) |
1 (1.00) |
0.113 (0.705) |
0.401 (0.921) |
0.766 (0.998) |
0.455 (0.949) |
0.474 (0.949) |
0.478 (0.949) |
0.685 (0.981) |
0.123 (0.712) |
0.835 (1.00) |
0.401 (0.921) |
0.99 (1.00) |
0.0966 (0.692) |
1 (1.00) |
0.708 (0.985) |
0.333 (0.899) |
0.855 (1.00) |
0.388 (0.921) |
0.141 (0.735) |
0.684 (0.981) |
0.927 (1.00) |
0.213 (0.822) |
1 (1.00) |
0.766 (0.998) |
0.735 (0.994) |
0.77 (0.998) |
0.484 (0.951) |
0.663 (0.981) |
0.916 (1.00) |
0.458 (0.949) |
0.28 (0.866) |
0.659 (0.981) |
0.218 (0.828) |
0.251 (0.857) |
del 20p12 1 | 36 (12%) | 259 |
0.145 (0.748) |
0.282 (0.866) |
0.565 (0.967) |
0.639 (0.971) |
1 (1.00) |
0.1 (0.692) |
0.787 (1) |
0.0935 (0.687) |
0.531 (0.953) |
0.622 (0.969) |
1 (1.00) |
0.283 (0.866) |
0.069 (0.649) |
0.99 (1.00) |
0.95 (1.00) |
0.0935 (0.687) |
0.0858 (0.671) |
0.932 (1.00) |
0.298 (0.881) |
0.652 (0.976) |
0.877 (1.00) |
0.708 (0.985) |
0.494 (0.953) |
0.745 (0.994) |
0.52 (0.953) |
0.401 (0.921) |
0.835 (1.00) |
1 (1.00) |
0.531 (0.953) |
0.358 (0.912) |
0.437 (0.943) |
0.607 (0.969) |
0.29 (0.871) |
0.713 (0.987) |
0.724 (0.989) |
0.577 (0.969) |
0.37 (0.919) |
0.693 (0.983) |
|
del 21q11 2 | 58 (20%) | 237 |
0.0358 (0.53) |
0.169 (0.768) |
0.0442 (0.538) |
0.219 (0.828) |
0.69 (0.981) |
0.14 (0.735) |
0.624 (0.969) |
0.562 (0.966) |
0.0647 (0.639) |
0.342 (0.902) |
0.052 (0.567) |
0.0986 (0.692) |
0.174 (0.774) |
0.0428 (0.533) |
0.562 (0.966) |
0.0331 (0.524) |
0.0244 (0.485) |
0.459 (0.949) |
0.0286 (0.504) |
0.314 (0.89) |
0.839 (1.00) |
0.0424 (0.533) |
0.154 (0.749) |
0.766 (0.998) |
0.0584 (0.603) |
0.964 (1.00) |
0.835 (1.00) |
0.0647 (0.639) |
0.188 (0.79) |
0.667 (0.981) |
0.156 (0.749) |
0.444 (0.948) |
0.448 (0.948) |
0.351 (0.906) |
0.73 (0.993) |
0.153 (0.749) |
0.0405 (0.53) |
||
del 22q13 32 | 88 (30%) | 207 |
0.144 (0.747) |
0.215 (0.827) |
0.383 (0.921) |
0.226 (0.84) |
0.494 (0.953) |
0.373 (0.921) |
0.277 (0.866) |
0.549 (0.962) |
0.768 (0.998) |
0.819 (1.00) |
0.804 (1.00) |
0.761 (0.998) |
1 (1.00) |
0.531 (0.953) |
0.134 (0.723) |
0.549 (0.962) |
0.463 (0.949) |
0.149 (0.749) |
0.258 (0.857) |
0.00957 (0.444) |
0.145 (0.748) |
0.572 (0.968) |
0.02 (0.452) |
0.64 (0.971) |
0.9 (1.00) |
0.861 (1.00) |
0.19 (0.79) |
0.218 (0.828) |
0.768 (0.998) |
0.193 (0.793) |
0.715 (0.987) |
0.937 (1.00) |
0.876 (1.00) |
0.187 (0.79) |
0.171 (0.774) |
0.246 (0.857) |
0.651 (0.976) |
0.247 (0.857) |
0.16 (0.757) |
del xp11 3 | 72 (24%) | 223 |
0.427 (0.934) |
0.205 (0.808) |
0.807 (1.00) |
0.57 (0.968) |
0.686 (0.981) |
0.425 (0.934) |
0.097 (0.692) |
0.522 (0.953) |
1 (1.00) |
0.096 (0.692) |
0.113 (0.705) |
0.666 (0.981) |
0.336 (0.899) |
0.472 (0.949) |
0.178 (0.778) |
0.522 (0.953) |
0.382 (0.921) |
0.359 (0.913) |
0.284 (0.866) |
0.353 (0.907) |
0.759 (0.998) |
0.122 (0.712) |
0.108 (0.699) |
0.581 (0.969) |
0.644 (0.974) |
0.244 (0.857) |
0.279 (0.866) |
0.847 (1.00) |
1 (1.00) |
0.863 (1.00) |
0.105 (0.694) |
0.092 (0.687) |
0.0715 (0.661) |
0.726 (0.99) |
0.0682 (0.645) |
1 (1.00) |
0.225 (0.84) |
0.181 (0.781) |
0.504 (0.953) |
del xq21 33 | 60 (20%) | 235 |
0.0275 (0.503) |
0.427 (0.934) |
0.775 (0.998) |
0.434 (0.94) |
0.37 (0.919) |
0.843 (1.00) |
0.154 (0.749) |
0.763 (0.998) |
0.47 (0.949) |
0.187 (0.79) |
0.414 (0.926) |
0.164 (0.767) |
0.0415 (0.533) |
0.48 (0.949) |
0.575 (0.969) |
0.763 (0.998) |
0.684 (0.981) |
0.623 (0.969) |
0.188 (0.79) |
0.172 (0.774) |
0.583 (0.969) |
0.414 (0.926) |
0.0318 (0.515) |
0.952 (1.00) |
0.585 (0.969) |
0.102 (0.692) |
0.079 (0.663) |
1 (1.00) |
0.47 (0.949) |
0.906 (1.00) |
0.0432 (0.534) |
0.76 (0.998) |
0.813 (1.00) |
0.766 (0.998) |
0.116 (0.705) |
0.132 (0.715) |
0.635 (0.97) |
0.395 (0.921) |
0.876 (1.00) |
P value = 0.000111 (Wilcoxon-test), Q value = 0.046
nPatients | Mean (Std.Dev) | |
---|---|---|
ALL | 293 | 48.1 (13.8) |
AMP PEAK 16(11Q22.1) MUTATED | 47 | 40.9 (12.6) |
AMP PEAK 16(11Q22.1) WILD-TYPE | 246 | 49.5 (13.6) |
P value = 9.19e-05 (Wilcoxon-test), Q value = 0.045
nPatients | Mean (Std.Dev) | |
---|---|---|
ALL | 295 | 48.2 (13.8) |
AMP PEAK 16(11Q22.1) MUTATED | 47 | 40.9 (12.6) |
AMP PEAK 16(11Q22.1) WILD-TYPE | 248 | 49.6 (13.6) |
P value = 8e-05 (Fisher's exact test), Q value = 0.045
nPatients | ADENOSQUAMOUS | CERVICAL SQUAMOUS CELL CARCINOMA | ENDOCERVICAL ADENOCARCINOMA OF THE USUAL TYPE | ENDOCERVICAL TYPE OF ADENOCARCINOMA | ENDOMETRIOID ADENOCARCINOMA OF ENDOCERVIX | MUCINOUS ADENOCARCINOMA OF ENDOCERVICAL TYPE |
---|---|---|---|---|---|---|
ALL | 6 | 242 | 6 | 21 | 3 | 17 |
DEL PEAK 5(3P14.2) MUTATED | 2 | 124 | 1 | 1 | 1 | 5 |
DEL PEAK 5(3P14.2) WILD-TYPE | 4 | 118 | 5 | 20 | 2 | 12 |
P value = 0.00053 (Fisher's exact test), Q value = 0.19
nPatients | CURRENT REFORMED SMOKER FOR < OR = 15 YEARS | CURRENT REFORMED SMOKER FOR > 15 YEARS | CURRENT REFORMED SMOKER, DURATION NOT SPECIFIED | CURRENT SMOKER | LIFELONG NON-SMOKER |
---|---|---|---|---|---|
ALL | 38 | 9 | 3 | 62 | 143 |
DEL PEAK 5(3P14.2) MUTATED | 16 | 2 | 3 | 40 | 53 |
DEL PEAK 5(3P14.2) WILD-TYPE | 22 | 7 | 0 | 22 | 90 |
P value = 0.000747 (Wilcoxon-test), Q value = 0.23
nPatients | Mean (Std.Dev) | |
---|---|---|
ALL | 293 | 2008.5 (4.6) |
DEL PEAK 12(6Q26) MUTATED | 98 | 2007.2 (5.2) |
DEL PEAK 12(6Q26) WILD-TYPE | 195 | 2009.2 (4.2) |
P value = 0.000904 (Wilcoxon-test), Q value = 0.25
nPatients | Mean (Std.Dev) | |
---|---|---|
ALL | 293 | 48.1 (13.8) |
DEL PEAK 16(10Q23.31) MUTATED | 86 | 52.2 (14.5) |
DEL PEAK 16(10Q23.31) WILD-TYPE | 207 | 46.4 (13.2) |
P value = 2e-05 (Fisher's exact test), Q value = 0.025
nPatients | ADENOSQUAMOUS | CERVICAL SQUAMOUS CELL CARCINOMA | ENDOCERVICAL ADENOCARCINOMA OF THE USUAL TYPE | ENDOCERVICAL TYPE OF ADENOCARCINOMA | ENDOMETRIOID ADENOCARCINOMA OF ENDOCERVIX | MUCINOUS ADENOCARCINOMA OF ENDOCERVICAL TYPE |
---|---|---|---|---|---|---|
ALL | 6 | 242 | 6 | 21 | 3 | 17 |
DEL PEAK 24(16Q11.2) MUTATED | 0 | 32 | 5 | 9 | 1 | 6 |
DEL PEAK 24(16Q11.2) WILD-TYPE | 6 | 210 | 1 | 12 | 2 | 11 |
P value = 5e-05 (Fisher's exact test), Q value = 0.041
nPatients | ADENOSQUAMOUS | CERVICAL SQUAMOUS CELL CARCINOMA | ENDOCERVICAL ADENOCARCINOMA OF THE USUAL TYPE | ENDOCERVICAL TYPE OF ADENOCARCINOMA | ENDOMETRIOID ADENOCARCINOMA OF ENDOCERVIX | MUCINOUS ADENOCARCINOMA OF ENDOCERVICAL TYPE |
---|---|---|---|---|---|---|
ALL | 6 | 242 | 6 | 21 | 3 | 17 |
DEL PEAK 25(16Q23.1) MUTATED | 0 | 34 | 4 | 9 | 2 | 6 |
DEL PEAK 25(16Q23.1) WILD-TYPE | 6 | 208 | 2 | 12 | 1 | 11 |
P value = 1e-05 (Fisher's exact test), Q value = 0.025
nPatients | ADENOSQUAMOUS | CERVICAL SQUAMOUS CELL CARCINOMA | ENDOCERVICAL ADENOCARCINOMA OF THE USUAL TYPE | ENDOCERVICAL TYPE OF ADENOCARCINOMA | ENDOMETRIOID ADENOCARCINOMA OF ENDOCERVIX | MUCINOUS ADENOCARCINOMA OF ENDOCERVICAL TYPE |
---|---|---|---|---|---|---|
ALL | 6 | 242 | 6 | 21 | 3 | 17 |
DEL PEAK 28(18Q21.2) MUTATED | 0 | 55 | 1 | 14 | 2 | 10 |
DEL PEAK 28(18Q21.2) WILD-TYPE | 6 | 187 | 5 | 7 | 1 | 7 |
-
Copy number data file = all_lesions.txt from GISTIC pipeline
-
Processed Copy number data file = /xchip/cga/gdac-prod/tcga-gdac/jobResults/GDAC_Correlate_Genomic_Events_Preprocess/CESC-TP/19779737/transformed.cor.cli.txt
-
Clinical data file = /xchip/cga/gdac-prod/tcga-gdac/jobResults/Append_Data/CESC-TP/19775059/CESC-TP.merged_data.txt
-
Number of patients = 295
-
Number of significantly focal cnvs = 63
-
Number of selected clinical features = 39
-
Exclude genes that fewer than K tumors have mutations, K = 3
For survival clinical features, the Kaplan-Meier survival curves of tumors with and without gene mutations were plotted and the statistical significance P values were estimated by logrank test (Bland and Altman 2004) using the 'survdiff' function in R
For binary or multi-class clinical features (nominal or ordinal), two-tailed Fisher's exact tests (Fisher 1922) were used to estimate the P values using the 'fisher.test' function in R
For multiple hypothesis correction, Q value is the False Discovery Rate (FDR) analogue of the P value (Benjamini and Hochberg 1995), defined as the minimum FDR at which the test may be called significant. We used the 'Benjamini and Hochberg' method of 'p.adjust' function in R to convert P values into Q values.
In addition to the links below, the full results of the analysis summarized in this report can also be downloaded programmatically using firehose_get, or interactively from either the Broad GDAC website or TCGA Data Coordination Center Portal.