Clinical Features CN_CNMF METHLYATION_CNMF RPPA_CNMF RPPA_CHIERARCHICAL MRNASEQ_CNMF MRNASEQ_CHIERARCHICAL MIRSEQ_CNMF MIRSEQ_CHIERARCHICAL MIRSEQ_MATURE_CNMF MIRSEQ_MATURE_CHIERARCHICAL nCNV (%) nWild-Type Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q 1p gain 10 (28%) 26 0.13937 1 0.64898 1 0.65296 1 0.79319 1 0.63417 1 0.55021 1 0.10757 1 0.2636 1 0.26005 1 0.68832 1 1q gain 21 (58%) 15 0.516 1 0.093069 1 1 1 1 1 0.6913 1 0.235 1 0.11443 1 0.17692 1 0.73579 1 0.5918 1 2p gain 6 (17%) 30 0.66171 1 0.63104 1 1 1 0.63512 1 1 1 0.92107 1 0.36575 1 0.54641 1 1 1 0.5986 1 2q gain 6 (17%) 30 0.18213 1 0.62799 1 0.72605 1 0.71944 1 0.52594 1 0.5027 1 0.36948 1 0.39676 1 1 1 0.60071 1 3p gain 3 (8%) 33 0.23095 1 0.096489 1 NA NA NA NA 0.32467 1 0.15316 1 0.33803 1 0.23635 1 0.063725 1 0.57665 1 3q gain 8 (22%) 28 0.2357 1 0.059279 1 0.18505 1 0.7163 1 0.10127 1 0.099389 1 0.53964 1 0.66655 1 1 1 0.39776 1 4p gain 3 (8%) 33 1 1 1 1 NA NA NA NA 1 1 0.79131 1 0.76916 1 0.42282 1 0.55882 1 1 1 5p gain 12 (33%) 24 1 1 0.82204 1 0.88462 1 0.19967 1 0.61471 1 0.97723 1 0.76138 1 1 1 1 1 0.76107 1 5q gain 12 (33%) 24 1 1 0.82408 1 0.88388 1 0.19902 1 0.61265 1 0.97768 1 0.76394 1 1 1 1 1 0.7624 1 6p gain 7 (19%) 29 0.68426 1 1 1 0.85983 1 1 1 0.37092 1 0.89306 1 0.18522 1 0.31673 1 0.67378 1 0.23883 1 7p gain 7 (19%) 29 0.68426 1 1 1 1 1 0.29965 1 0.20851 1 0.38766 1 0.37263 1 0.56623 1 0.67378 1 0.0183 0.636 7q gain 6 (17%) 30 1 1 0.63005 1 0.52533 1 0.68921 1 0.44758 1 0.53361 1 0.68666 1 0.82002 1 1 1 0.0067799 0.53 8p gain 6 (17%) 30 1 1 0.23885 1 0.39254 1 0.67021 1 0.33722 1 0.16686 1 0.20403 1 0.36397 1 0.36668 1 0.1162 1 8q gain 12 (33%) 24 1 1 0.20486 1 0.38334 1 0.57038 1 0.16969 1 0.53705 1 0.18381 1 0.16628 1 0.72102 1 0.1318 1 10p gain 5 (14%) 31 1 1 0.3972 1 0.39075 1 0.04057 0.884 0.83517 1 0.073799 1 0.78494 1 0.93396 1 0.62957 1 0.86328 1 11p gain 4 (11%) 32 0.60519 1 0.17651 1 0.60286 1 0.10294 1 0.20271 1 0.0058099 0.53 0.74002 1 0.74875 1 0.28699 1 0.18666 1 11q gain 4 (11%) 32 0.60519 1 0.17614 1 0.59747 1 0.10351 1 0.20211 1 0.0055399 0.53 0.73885 1 0.74759 1 0.28699 1 0.18463 1 12p gain 9 (25%) 27 1 1 0.55827 1 0.04537 0.907 0.23737 1 1 1 0.90519 1 0.46336 1 0.84184 1 0.4427 1 0.33515 1 12q gain 8 (22%) 28 1 1 0.53308 1 0.15361 1 0.53638 1 0.88033 1 0.98308 1 0.43657 1 0.82438 1 0.23576 1 0.62868 1 13q gain 3 (8%) 33 0.23095 1 0.096699 1 NA NA NA NA 0.04152 0.884 0.0396 0.884 0.39533 1 0.88825 1 1 1 0.02495 0.686 15q gain 6 (17%) 30 0.66171 1 0.85937 1 1 1 0.91422 1 0.86256 1 0.65574 1 0.19416 1 0.43868 1 0.67737 1 0.0088699 0.532 16p gain 7 (19%) 29 0.091789 1 0.57337 1 0.72705 1 0.63297 1 0.66274 1 0.63952 1 0.37378 1 0.91353 1 0.67378 1 0.29825 1 16q gain 5 (14%) 31 0.34199 1 1 1 0.80698 1 0.094969 1 1 1 0.62501 1 0.92263 1 0.93245 1 1 1 0.92694 1 17p gain 3 (8%) 33 1 1 1 1 0.59864 1 0.24933 1 0.77449 1 0.21288 1 0.6846 1 0.61145 1 0.55882 1 0.57895 1 17q gain 7 (19%) 29 1 1 1 1 0.15257 1 0.53329 1 0.49507 1 0.25608 1 0.93432 1 1 1 0.41782 1 0.52377 1 18p gain 7 (19%) 29 1 1 0.75915 1 0.065939 1 0.30184 1 0.66497 1 0.75992 1 0.48522 1 0.88136 1 0.41782 1 0.8467 1 18q gain 6 (17%) 30 0.39108 1 0.33247 1 0.32135 1 0.67553 1 0.069529 1 0.57006 1 0.19452 1 0.43763 1 0.67737 1 0.39261 1 19p gain 6 (17%) 30 0.66171 1 0.85848 1 0.70152 1 0.72215 1 0.6276 1 0.65711 1 0.58062 1 0.4348 1 0.062805 1 1 1 19q gain 6 (17%) 30 0.66171 1 0.85929 1 0.70578 1 0.72078 1 0.62572 1 0.65952 1 0.58148 1 0.43849 1 0.062805 1 1 1 20p gain 11 (31%) 25 1 1 0.60711 1 0.31193 1 0.47829 1 0.7256 1 0.42314 1 0.23566 1 0.28204 1 0.46459 1 0.33972 1 20q gain 12 (33%) 24 0.73173 1 0.61479 1 0.14333 1 0.26639 1 0.75211 1 0.28271 1 0.14227 1 0.14883 1 0.49911 1 0.2243 1 21q gain 3 (8%) 33 1 1 0.48131 1 1 1 0.67753 1 0.4585 1 0.88684 1 0.18522 1 0.71105 1 0.25 1 0.13277 1 22q gain 5 (14%) 31 0.34199 1 0.59876 1 0.80989 1 1 1 0.085579 1 0.28706 1 0.84841 1 0.93328 1 1 1 0.92802 1 1p loss 4 (11%) 32 1 1 1 1 0.5283 1 0.75182 1 0.65699 1 0.60967 1 0.81534 1 0.79431 1 0.62567 1 0.81256 1 3p loss 22 (61%) 14 0.0022205 0.366 0.25156 1 1 1 0.061569 1 0.62017 1 0.01191 0.561 0.77243 1 0.58629 1 0.49921 1 0.99079 1 3q loss 3 (8%) 33 0.59286 1 0.47884 1 NA NA NA NA 0.16283 1 0.02204 0.649 0.69048 1 0.6126 1 0.55882 1 0.39433 1 4p loss 10 (28%) 26 0.27417 1 0.10063 1 1 1 1 1 0.22289 1 0.32206 1 0.78652 1 0.64633 1 0.7086 1 0.28836 1 4q loss 13 (36%) 23 1 1 0.39042 1 0.61779 1 0.68836 1 0.36926 1 0.39071 1 0.4597 1 0.83873 1 0.73555 1 0.36772 1 6p loss 5 (14%) 31 0.65043 1 0.02262 0.649 0.70231 1 1 1 0.70363 1 0.98263 1 0.3706 1 0.24035 1 0.62957 1 0.98201 1 6q loss 20 (56%) 16 0.00024181 0.16 0.01294 0.569 0.088699 1 0.02197 0.649 0.19296 1 0.14567 1 0.20942 1 0.25611 1 0.32043 1 0.40915 1 7p loss 4 (11%) 32 0.60519 1 0.4258 1 NA NA NA NA 0.43027 1 0.28001 1 0.51618 1 0.90429 1 1 1 0.8576 1 7q loss 4 (11%) 32 1 1 0.42317 1 NA NA NA NA 0.42838 1 0.28484 1 0.3208 1 0.27653 1 0.28699 1 0.39135 1 8p loss 10 (28%) 26 0.71692 1 0.12817 1 1 1 0.54683 1 0.01739 0.636 0.077499 1 0.093509 1 0.03747 0.883 0.26005 1 0.17165 1 8q loss 3 (8%) 33 0.59286 1 0.26249 1 0.76521 1 0.52422 1 0.24224 1 0.79276 1 0.76881 1 0.075579 1 1 1 0.13312 1 9p loss 18 (50%) 18 1 1 0.28353 1 0.2688 1 0.0066499 0.53 0.69364 1 0.29806 1 0.18582 1 0.12713 1 0.49979 1 0.59144 1 9q loss 19 (53%) 17 1 1 0.76967 1 0.25857 1 0.01145 0.561 0.58122 1 0.13173 1 0.71016 1 0.37008 1 0.19221 1 0.60429 1 10p loss 6 (17%) 30 1 1 0.86095 1 0.20557 1 0.11103 1 0.73253 1 0.36221 1 0.57954 1 0.77687 1 0.67737 1 0.01504 0.584 10q loss 5 (14%) 31 0.16721 1 0.59707 1 1 1 0.67553 1 0.40856 1 0.98168 1 0.84991 1 0.6973 1 1 1 0.55749 1 11p loss 8 (22%) 28 0.43385 1 1 1 0.065649 1 0.48841 1 0.20733 1 0.53148 1 1 1 0.8404 1 0.69403 1 0.3894 1 11q loss 9 (25%) 27 0.25529 1 1 1 0.26832 1 0.48203 1 0.072699 1 0.47443 1 0.76644 1 0.58301 1 0.70496 1 0.75949 1 12q loss 3 (8%) 33 0.23095 1 0.47819 1 NA NA NA NA 0.32594 1 0.15529 1 0.60809 1 1 1 1 1 0.39946 1 13q loss 15 (42%) 21 1 1 1 1 0.27031 1 0.51645 1 0.63079 1 0.74388 1 0.75742 1 0.31184 1 0.73579 1 0.33516 1 14q loss 13 (36%) 23 0.013954 0.576 0.56352 1 0.24736 1 0.0072699 0.53 1 1 0.04363 0.9 1 1 0.91098 1 0.4837 1 0.28095 1 15q loss 5 (14%) 31 0.34199 1 0.59641 1 1 1 1 1 0.084959 1 0.28755 1 0.51119 1 0.75546 1 0.62957 1 0.98221 1 16p loss 4 (11%) 32 1 1 1 1 NA NA NA NA 0.80673 1 1 1 0.73899 1 0.96557 1 0.62567 1 0.18727 1 16q loss 7 (19%) 29 0.68426 1 0.33296 1 0.39248 1 0.42941 1 0.66171 1 0.41417 1 0.65888 1 0.01929 0.637 1 1 0.66234 1 17p loss 10 (28%) 26 0.71692 1 0.51962 1 0.85823 1 1 1 0.1146 1 0.35183 1 0.25222 1 0.29061 1 1 1 0.14275 1 18p loss 6 (17%) 30 1 1 1 1 0.65197 1 0.48045 1 0.44975 1 0.60344 1 0.24016 1 0.57129 1 0.36668 1 0.30705 1 18q loss 8 (22%) 28 0.2357 1 0.7006 1 0.58262 1 0.83936 1 0.10299 1 0.61379 1 0.13247 1 0.25241 1 0.42405 1 0.063049 1 19p loss 4 (11%) 32 0.60519 1 0.2958 1 0.80657 1 1 1 0.14642 1 0.6825 1 0.051369 0.997 0.24175 1 0.12478 1 0.0080299 0.53 19q loss 3 (8%) 33 1 1 0.48248 1 NA NA NA NA 0.3275 1 0.7325 1 0.86177 1 1 1 1 1 0.57924 1 20p loss 5 (14%) 31 1 1 0.59462 1 NA NA NA NA 0.03192 0.78 0.51929 1 0.097679 1 0.41545 1 0.37611 1 0.01131 0.561 21q loss 15 (42%) 21 0.31067 1 1 1 1 1 0.71499 1 0.13301 1 0.28838 1 0.33655 1 0.62907 1 0.31037 1 0.68961 1 22q loss 5 (14%) 31 0.65043 1 0.8381 1 0.70369 1 0.37632 1 0.33122 1 0.15236 1 0.67686 1 0.80501 1 0.37611 1 0.4014 1 xp loss 15 (42%) 21 0.0018513 0.366 0.02715 0.694 0.65027 1 0.84909 1 1 1 0.26536 1 0.57368 1 0.96094 1 0.50061 1 0.99586 1 xq loss 15 (42%) 21 0.0018513 0.366 0.02735 0.694 0.64865 1 0.84921 1 1 1 0.26512 1 0.5733 1 0.96222 1 0.50061 1 0.99604 1