Clinical Features	MRNA_CNMF		MRNA_CHIERARCHICAL		MIR_CNMF		MIR_CHIERARCHICAL		CN_CNMF		METHLYATION_CNMF		RPPA_CNMF		RPPA_CHIERARCHICAL		MRNASEQ_CNMF		MRNASEQ_CHIERARCHICAL	
	nMutated (%)	nWild-Type	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q
TP53	80 (28%)	203	0.00099999	0.0164	9.9999e-06	0.00045	0.00081999	0.0148	0.20305	0.703	2e-05	0.00072	0.00086999	0.0149	0.0073199	0.0826	0.04616	0.32	0.00075999	0.0146	0.00053999	0.0114
PIK3R1	32 (11%)	251	0.75304	1	0.18708	0.7	0.2002	0.703	0.52701	1	0.63668	1	0.24944	0.781	0.2171	0.729	0.058579	0.37	0.40475	0.964	0.22156	0.729
RB1	24 (8%)	259	0.03398	0.255	0.01694	0.156	0.13253	0.635	0.9227	1	0.10748	0.553	0.01081	0.114	0.81669	1	0.53733	1	0.079599	0.455	0.57904	1
NF1	29 (10%)	254	0.081189	0.457	0.00027	0.00648	0.02534	0.212	0.93163	1	0.0083899	0.0915	0.068419	0.417	0.051899	0.34	0.01199	0.123	0.56467	1	0.45108	1
PTEN	87 (31%)	196	0.11611	0.581	0.074979	0.437	0.02627	0.215	0.64656	1	0.42891	0.996	0.22309	0.729	0.24851	0.781	0.382	0.955	0.27109	0.805	0.64457	1
IDH1	14 (5%)	269	0.00014	0.00388	9.9999e-06	0.00045	4e-05	0.00131	0.00283	0.0408	6.9999e-05	0.0021	9.9999e-06	0.00045	0.26605	0.798	0.0073399	0.0826	0.00076999	0.0146	9.9999e-06	0.00045
PIK3CA	27 (10%)	256	0.95352	1	0.28936	0.832	0.29122	0.832	0.86053	1	0.67105	1	0.86663	1	0.81136	1	0.40524	0.964	0.40658	0.964	0.23155	0.738
STAG2	12 (4%)	271	0.39175	0.959	0.69734	1	0.71553	1	0.59002	1	0.754	1	0.04323	0.305	0.27493	0.805	0.33501	0.912	0.4785	1	0.10512	0.553
SLC26A3	7 (2%)	276	0.94183	1	0.76695	1	0.46457	1	0.36581	0.935	0.64824	1	0.18193	0.697	0.4804	1	0.30904	0.856	0.15606	0.679	0.16339	0.68
SEMG1	8 (3%)	275	0.6792	1	0.17676	0.688	0.88781	1	1	1	0.16424	0.68	0.16828	0.688	NA	NA	NA	NA	1	1	0.33938	0.912
KDR	8 (3%)	275	0.20307	0.703	0.65758	1	0.28157	0.817	0.51149	1	0.73254	1	0.34645	0.917	0.15657	0.679	0.73338	1	NA	NA	NA	NA
RPL5	7 (2%)	276	0.38222	0.955	0.50875	1	0.86773	1	0.46685	1	1	1	NA	NA	0.55092	1	0.68785	1	0.46336	1	1	1
ATRX	16 (6%)	267	0.00213	0.0322	9.9999e-06	0.00045	0.0061299	0.0761	0.01809	0.163	2e-05	0.00072	9.9999e-06	0.00045	0.55572	1	0.01412	0.134	0.00215	0.0322	0.00018	0.00463
MAP3K1	6 (2%)	277	1	1	0.72957	1	0.80797	1	0.64631	1	1	1	NA	NA	NA	NA	NA	NA	0.57148	1	1	1
BRAF	6 (2%)	277	0.7675	1	0.71286	1	0.31802	0.874	0.02913	0.223	0.59078	1	NA	NA	1	1	0.78248	1	0.79347	1	1	1
EGFR	74 (26%)	209	0.0069599	0.0826	0.056669	0.364	0.50697	1	0.137	0.641	9.9999e-06	0.00045	0.00033	0.00742	0.25748	0.789	9.9999e-06	0.00045	0.04186	0.301	0.0060799	0.0761
TMPRSS6	6 (2%)	277	0.66466	1	0.69906	1	0.66259	1	0.26402	0.798	0.88213	1	0.34636	0.917	0.90364	1	0.47117	1	0.57601	1	1	1
PRKCD	3 (1%)	280	0.17305	0.688	0.085519	0.474	0.16393	0.68	1	1	0.37702	0.955	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA
TP63	6 (2%)	277	1	1	0.7298	1	0.41026	0.965	0.64457	1	0.77404	1	NA	NA	0.03667	0.269	0.38518	0.955	0.25254	0.784	0.11179	0.567
PDGFRA	11 (4%)	272	0.01283	0.125	0.14615	0.658	0.90173	1	0.14144	0.653	0.1925	0.7	0.72842	1	0.29641	0.84	0.73205	1	0.02528	0.212	0.00489	0.0652
CHD8	9 (3%)	274	0.70217	1	0.53384	1	0.13411	0.635	0.64314	1	0.19067	0.7	NA	NA	0.30923	0.856	0.91536	1	0.27471	0.805	0.61104	1
IL4R	8 (3%)	275	0.94039	1	0.38748	0.955	0.71938	1	0.8068	1	0.90889	1	0.02776	0.222	0.22649	0.729	0.88594	1	0.46694	1	0.79904	1
REN	5 (2%)	278	0.4806	1	0.41604	0.973	0.073499	0.437	0.51394	1	0.61803	1	NA	NA	0.55216	1	1	1	NA	NA	NA	NA
CD209	5 (2%)	278	0.91184	1	1	1	0.066779	0.414	0.60746	1	0.6926	1	NA	NA	0.90566	1	1	1	NA	NA	NA	NA
FBN3	11 (4%)	272	0.19232	0.7	0.30841	0.856	0.90421	1	0.91961	1	0.10643	0.553	1	1	0.01899	0.167	0.66226	1	0.85485	1	1	1
MMP13	5 (2%)	278	0.91186	1	0.21933	0.729	0.76052	1	0.04997	0.339	0.15337	0.679	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA
TCF12	4 (1%)	279	1	1	0.48225	1	0.63958	1	0.25871	0.789	0.49015	1	NA	NA	0.075249	0.437	1	1	NA	NA	NA	NA
LZTR1	10 (4%)	273	1	1	0.51647	1	0.36042	0.933	0.70443	1	0.4414	1	0.12473	0.615	0.19972	0.703	0.56321	1	0.174	0.688	0.75419	1
ZDHHC4	3 (1%)	280	NA	NA	NA	NA	0.16282	0.68	1	1	0.050879	0.339	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA
IL18RAP	7 (2%)	276	0.12892	0.627	0.2269	0.729	0.00351	0.0486	0.17777	0.688	1	1	0.46878	1	0.36635	0.935	0.61416	1	0.68777	1	0.33887	0.912
ODF4	3 (1%)	280	0.87778	1	0.35226	0.926	1	1	0.19627	0.703	0.63332	1	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA
KEL	15 (5%)	268	0.54724	1	0.21194	0.727	0.72218	1	0.88573	1	0.090729	0.492	0.17102	0.688	0.67117	1	0.59615	1	0.40699	0.964	0.64891	1
TESK1	3 (1%)	280	0.35917	0.933	0.69703	1	0.45652	1	0.6044	1	0.78259	1	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA
MUC17	22 (8%)	261	0.01243	0.124	0.19104	0.7	0.70353	1	0.70398	1	0.92279	1	0.84104	1	0.55063	1	0.091499	0.492	0.85901	1	1	1
FAM126B	4 (1%)	279	0.39458	0.96	0.02895	0.223	0.64053	1	0.44319	1	0.47611	1	0.4536	1	1	1	0.62973	1	NA	NA	NA	NA
DDX5	4 (1%)	279	0.21627	0.729	1	1	0.53615	1	0.44333	1	0.14396	0.656	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA