Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.011 0.067 0.228 13.0 -9999.0 0.0 13.0 KIRREL -0.019 0.095 -9999.0 0.0 -0.331 13.0 13.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.011 0.067 -9999.0 0.0 -0.229 13.0 13.0 PLCG1 0.007 0.027 -9999.0 0.0 -0.326 1.0 1.0 ARRB2 0.009 0.0 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.009 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP 0.0 0.049 -9999.0 0.0 -0.159 13.0 13.0 ChemicalAbstracts:57-88-5 -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.004 0.055 -9999.0 0.0 -0.184 13.0 13.0 FYN -0.006 0.046 -9999.0 0.0 -0.157 13.0 13.0 mol:Ca2+ -0.001 0.054 -9999.0 0.0 -0.171 13.0 13.0 mol:DAG -0.001 0.054 -9999.0 0.0 -0.172 13.0 13.0 NPHS2 -0.0 0.012 -9999.0 0.0 -9999.0 0.0 0.0 mol:IP3 -0.001 0.054 -9999.0 0.0 -0.172 13.0 13.0 regulation of endocytosis 0.002 0.045 -9999.0 0.0 -0.146 13.0 13.0 Nephrin/NEPH1/podocin/Cholesterol -0.005 0.048 -9999.0 0.0 -0.161 13.0 13.0 establishment of cell polarity -0.011 0.067 -9999.0 0.0 -0.228 13.0 13.0 Nephrin/NEPH1/podocin/NCK1-2 0.006 0.046 -9999.0 0.0 -0.142 13.0 13.0 Nephrin/NEPH1/beta Arrestin2 0.003 0.046 -9999.0 0.0 -0.147 13.0 13.0 NPHS1 0.001 0.011 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin -0.004 0.048 -9999.0 0.0 -0.158 13.0 13.0 TJP1 0.009 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.009 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.009 0.0 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.001 0.054 -9999.0 0.0 -0.172 13.0 13.0 CD2AP 0.009 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 0.0 0.049 -9999.0 0.0 -0.159 13.0 13.0 GRB2 0.009 0.0 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.013 0.059 -9999.0 0.0 -0.157 21.0 21.0 cytoskeleton organization -0.004 0.055 -9999.0 0.0 -0.182 13.0 13.0 Nephrin/NEPH1 -0.005 0.045 -9999.0 0.0 -0.152 13.0 13.0 Nephrin/NEPH1/ZO-1 -0.001 0.053 -9999.0 0.0 -0.173 13.0 13.0