Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity -0.014 0.081 0.243 13.0 -9999.0 0.0 13.0 KIRREL -0.0 0.105 -9999.0 0.0 -0.335 13.0 13.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs 0.014 0.082 -9999.0 0.0 -0.243 13.0 13.0 PLCG1 0.024 0.03 -9999.0 0.0 -0.325 1.0 1.0 ARRB2 0.029 0.004 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.021 0.014 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP 0.04 0.076 -9999.0 0.0 -0.186 13.0 13.0 ChemicalAbstracts:57-88-5 -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.0 0.051 -9999.0 0.0 -0.198 9.0 9.0 FYN -0.021 0.067 0.149 11.0 -0.178 13.0 24.0 mol:Ca2+ 0.035 0.079 -9999.0 0.0 -0.197 13.0 13.0 mol:DAG 0.036 0.08 -9999.0 0.0 -0.197 13.0 13.0 NPHS2 -0.009 0.03 -9999.0 0.0 -9999.0 0.0 0.0 mol:IP3 0.036 0.08 -9999.0 0.0 -0.197 13.0 13.0 regulation of endocytosis 0.027 0.066 -9999.0 0.0 -0.173 13.0 13.0 Nephrin/NEPH1/podocin/Cholesterol 0.028 0.068 -9999.0 0.0 -0.179 13.0 13.0 establishment of cell polarity 0.014 0.081 -9999.0 0.0 -0.243 13.0 13.0 Nephrin/NEPH1/podocin/NCK1-2 0.054 0.078 -9999.0 0.0 -0.175 13.0 13.0 Nephrin/NEPH1/beta Arrestin2 0.029 0.067 -9999.0 0.0 -0.175 13.0 13.0 NPHS1 -0.003 0.031 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin 0.025 0.065 -9999.0 0.0 -0.179 13.0 13.0 TJP1 0.029 0.005 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.029 0.004 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.029 0.003 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 0.037 0.081 -9999.0 0.0 -0.198 13.0 13.0 CD2AP 0.029 0.006 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 0.044 0.074 -9999.0 0.0 -0.186 12.0 12.0 GRB2 0.029 0.004 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.029 0.08 0.153 12.0 -0.179 21.0 33.0 cytoskeleton organization -0.021 0.05 0.189 1.0 -0.213 8.0 9.0 Nephrin/NEPH1 0.016 0.057 -9999.0 0.0 -0.162 13.0 13.0 Nephrin/NEPH1/ZO-1 0.03 0.072 -9999.0 0.0 -0.193 13.0 13.0