Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.017 0.014 -9999.0 0.0 -0.054 21.0 21.0 KIRREL -0.015 0.009 0.027 22.0 -9999.0 0.0 22.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.017 0.014 0.054 21.0 -9999.0 0.0 21.0 PLCG1 -0.014 0.0 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 -0.014 0.0 -9999.0 0.0 -9999.0 0.0 0.0 WASL -0.014 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.02 0.016 0.092 8.0 -9999.0 0.0 8.0 ChemicalAbstracts:57-88-5 -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.01 0.014 0.051 20.0 -9999.0 0.0 20.0 FYN -0.017 0.007 0.075 2.0 -9999.0 0.0 2.0 mol:Ca2+ -0.019 0.023 0.094 21.0 -9999.0 0.0 21.0 mol:DAG -0.019 0.024 0.096 21.0 -9999.0 0.0 21.0 NPHS2 -0.015 0.009 0.027 23.0 -9999.0 0.0 23.0 mol:IP3 -0.019 0.024 0.096 21.0 -9999.0 0.0 21.0 regulation of endocytosis -0.021 0.004 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/Cholesterol -0.013 0.022 0.093 21.0 -9999.0 0.0 21.0 establishment of cell polarity -0.017 0.014 0.054 21.0 -9999.0 0.0 21.0 Nephrin/NEPH1/podocin/NCK1-2 -0.022 0.026 0.109 20.0 -9999.0 0.0 20.0 Nephrin/NEPH1/beta Arrestin2 -0.021 0.007 0.071 2.0 -9999.0 0.0 2.0 NPHS1 -0.015 0.009 0.027 22.0 -9999.0 0.0 22.0 Nephrin/NEPH1/podocin -0.017 0.008 0.093 2.0 -9999.0 0.0 2.0 TJP1 -0.014 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 -0.014 0.002 0.0 11.0 -9999.0 0.0 11.0 NCK2 -0.014 0.001 0.0 1.0 -9999.0 0.0 1.0 heterophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.019 0.024 0.098 21.0 -9999.0 0.0 21.0 CD2AP -0.013 0.004 0.0 49.0 -9999.0 0.0 49.0 Nephrin/NEPH1/podocin/GRB2 -0.02 0.022 0.098 18.0 -9999.0 0.0 18.0 GRB2 -0.014 0.001 0.0 5.0 -9999.0 0.0 5.0 homophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.019 0.01 0.074 2.0 -9999.0 0.0 2.0 cytoskeleton organization -0.019 0.017 0.08 12.0 -9999.0 0.0 12.0 Nephrin/NEPH1 -0.01 0.011 0.045 21.0 -9999.0 0.0 21.0 Nephrin/NEPH1/ZO-1 -0.019 0.015 0.053 21.0 -9999.0 0.0 21.0