Stabilization and expansion of the E-cadherin adherens junction
Entity	Mean	Std Dev	Mean of Up Perturbations	Number of Up Perturbations	Mean of Down Perturbations	Number of Down Perturbations	Number of Total Perturbations
adherens junction organization	0.036	0.019	0.079	10.0	-0.11	2.0	12.0
epithelial cell differentiation	0.054	0.022	-9999.0	0.0	-0.042	22.0	22.0
CYFIP2	-0.016	0.014	0.0	220.0	-9999.0	0.0	220.0
ENAH	-0.058	0.058	0.341	5.0	-9999.0	0.0	5.0
EGFR	-0.011	0.014	0.0	311.0	-9999.0	0.0	311.0
EPHA2	-0.026	0.006	0.0	27.0	-9999.0	0.0	27.0
MYO6	-0.041	0.035	0.153	10.0	-9999.0	0.0	10.0
CTNNB1	-0.027	0.004	0.0	13.0	-9999.0	0.0	13.0
ABI1/Sra1/Nap1	0.019	0.034	-9999.0	0.0	-0.039	66.0	66.0
AQP5	-0.03	0.046	-9999.0	0.0	-0.328	7.0	7.0
CTNND1	-0.027	0.005	0.0	16.0	-9999.0	0.0	16.0
mol:PI-4-5-P2	-0.041	0.03	0.151	6.0	-9999.0	0.0	6.0
regulation of calcium-dependent cell-cell adhesion	-0.04	0.035	0.152	10.0	-9999.0	0.0	10.0
EGF	-0.028	0.003	0.0	8.0	-9999.0	0.0	8.0
NCKAP1	-0.028	0.002	0.0	2.0	-9999.0	0.0	2.0
AQP3	-0.045	0.077	-9999.0	0.0	-0.328	31.0	31.0
cortical microtubule organization	0.054	0.022	-9999.0	0.0	-0.042	22.0	22.0
GO:0000145	-0.04	0.027	0.136	6.0	-9999.0	0.0	6.0
E-cadherin/Ca2+/beta catenin/alpha catenin/p120 catenin	0.06	0.024	-9999.0	0.0	-0.042	22.0	22.0
MLLT4	-0.026	0.008	0.0	40.0	-9999.0	0.0	40.0
ARF6/GDP	-0.07	0.027	-9999.0	0.0	-9999.0	0.0	0.0
ARF6	-0.027	0.006	0.0	24.0	-9999.0	0.0	24.0
Ephrin A1/EPHA2/NCK1/GIT1	0.063	0.026	-9999.0	0.0	-0.046	14.0	14.0
mol:Ca2+	-0.0	0.0	-9999.0	0.0	-9999.0	0.0	0.0
VASP	-0.018	0.025	0.138	3.0	-0.205	1.0	4.0
PVRL2	-0.027	0.006	0.0	25.0	-9999.0	0.0	25.0
ZYX	-0.024	0.032	0.152	5.0	-9999.0	0.0	5.0
ARF6/GTP	0.065	0.036	-9999.0	0.0	-0.053	30.0	30.0
CDH1	-0.027	0.005	0.0	18.0	-9999.0	0.0	18.0
EGFR/EGFR/EGF/EGF	-0.02	0.031	0.056	12.0	-9999.0	0.0	12.0
RhoA/GDP	0.055	0.024	-9999.0	0.0	-0.05	22.0	22.0
actin cytoskeleton organization	-0.036	0.033	0.13	8.0	-9999.0	0.0	8.0
IGF-1R heterotetramer	-0.028	0.003	0.0	6.0	-9999.0	0.0	6.0
GIT1	-0.028	0.003	0.0	7.0	-9999.0	0.0	7.0
IGF1R	-0.028	0.003	0.0	6.0	-9999.0	0.0	6.0
IGF1	-0.027	0.004	0.0	10.0	-9999.0	0.0	10.0
DIAPH1	-0.237	0.265	-9999.0	0.0	-0.487	245.0	245.0
Wnt receptor signaling pathway	-0.054	0.022	0.042	22.0	-9999.0	0.0	22.0
RHOA	-0.027	0.005	0.0	15.0	-9999.0	0.0	15.0
RhoA/GTP	-0.07	0.027	-9999.0	0.0	-9999.0	0.0	0.0
CTNNA1	-0.028	0.003	0.0	8.0	-9999.0	0.0	8.0
VCL	-0.036	0.034	0.131	8.0	-9999.0	0.0	8.0
EFNA1	-0.026	0.007	0.0	33.0	-9999.0	0.0	33.0
LPP	-0.044	0.032	0.136	6.0	-9999.0	0.0	6.0
Ephrin A1/EPHA2	-0.048	0.03	0.056	30.0	-9999.0	0.0	30.0
SEC6/SEC8	-0.059	0.02	-9999.0	0.0	-9999.0	0.0	0.0
MGAT3	-0.04	0.035	0.153	10.0	-9999.0	0.0	10.0
HGF/MET	-0.035	0.032	0.056	14.0	-9999.0	0.0	14.0
HGF	-0.019	0.013	0.0	162.0	-9999.0	0.0	162.0
E-cadherin/Ca2+/beta catenin/alpha catenin/p120 catenin/EPLIN	0.036	0.019	0.079	10.0	-0.111	2.0	12.0
actin cable formation	-0.051	0.077	0.334	10.0	-0.23	7.0	17.0
KIAA1543	-0.033	0.026	0.138	8.0	-9999.0	0.0	8.0
KIFC3	-0.043	0.031	0.154	7.0	-9999.0	0.0	7.0
NCK1	-0.027	0.006	0.0	25.0	-9999.0	0.0	25.0
EXOC3	-0.027	0.005	0.0	16.0	-9999.0	0.0	16.0
ACTN1	-0.038	0.034	0.153	9.0	-9999.0	0.0	9.0
NCK1/GIT1	0.038	0.01	-9999.0	0.0	0.0	31.0	31.0
mol:GDP	0.054	0.022	-9999.0	0.0	-0.042	22.0	22.0
EXOC4	0.0	0.0	-9999.0	0.0	-9999.0	0.0	0.0
STX4	-0.044	0.033	0.153	9.0	-9999.0	0.0	9.0
PIP5K1C	-0.042	0.031	0.152	6.0	-9999.0	0.0	6.0
LIMA1	-0.004	0.01	0.0	436.0	-9999.0	0.0	436.0
ABI1	-0.022	0.012	0.0	115.0	-9999.0	0.0	115.0
ROCK1	-0.058	0.074	0.378	8.0	-9999.0	0.0	8.0
adherens junction assembly	-0.039	0.045	0.235	3.0	-0.211	9.0	12.0
IGF-1R heterotetramer/IGF1	-0.053	0.023	0.056	18.0	-9999.0	0.0	18.0
nectin-2(dimer)/I-afadin/I-afadin/nectin-2(dimer/I-afadin/I-afadin	0.036	0.013	-9999.0	0.0	0.0	58.0	58.0
MET	-0.019	0.013	0.0	168.0	-9999.0	0.0	168.0
PLEKHA7	-0.037	0.015	0.036	18.0	-9999.0	0.0	18.0
mol:GTP	0.061	0.025	-9999.0	0.0	-0.046	14.0	14.0
establishment of epithelial cell apical/basal polarity	-0.059	0.047	0.189	2.0	-9999.0	0.0	2.0
cortical actin cytoskeleton stabilization	0.036	0.019	0.079	10.0	-0.11	2.0	12.0
regulation of cell-cell adhesion	-0.036	0.033	0.13	8.0	-9999.0	0.0	8.0
E-cadherin/Ca2+/beta catenin/alpha catenin/p120 catenin/EPLIN/cortical actin cytoskeleton	0.036	0.019	0.079	10.0	-0.111	2.0	12.0