Ras signaling in the CD4+ TCR pathway Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations ERK1-2/ELK1 0.052 0.084 0.212 6.0 -0.26 5.0 11.0 MAP3K8 -0.01 0.023 0.012 234.0 -9999.0 0.0 234.0 FOS 0.035 0.076 0.192 6.0 -0.251 6.0 12.0 PRKCA -0.011 0.03 0.041 123.0 -9999.0 0.0 123.0 PTPN7 -0.009 0.034 0.052 121.0 -9999.0 0.0 121.0 HRAS -0.013 0.025 0.025 142.0 -9999.0 0.0 142.0 PRKCB 0.003 0.006 0.014 124.0 -9999.0 0.0 124.0 NRAS -0.01 0.022 0.012 229.0 -9999.0 0.0 229.0 RAS family/GTP 0.051 0.024 -9999.0 0.0 -0.033 17.0 17.0 MAPK3 0.038 0.04 -9999.0 0.0 -0.324 2.0 2.0 MAP2K1 0.014 0.037 0.13 7.0 -0.195 2.0 9.0 ELK1 -0.014 0.026 0.033 124.0 -9999.0 0.0 124.0 BRAF 0.007 0.016 0.086 2.0 -9999.0 0.0 2.0 mol:GTP 0.0 0.001 0.002 124.0 -0.001 2.0 126.0 MAPK1 0.014 0.104 -9999.0 0.0 -0.354 32.0 32.0 RAF1 0.01 0.024 0.092 4.0 -0.226 2.0 6.0 KRAS -0.013 0.024 0.03 119.0 -9999.0 0.0 119.0