type count De_novo_Start_InFrame 18 De_novo_Start_OutOfFrame 55 Frame_Shift_Del 1569 Frame_Shift_Ins 489 In_Frame_Del 624 In_Frame_Ins 46 Missense_Mutation 35748 Nonsense_Mutation 2173 Nonstop_Mutation 28 Silent 13644 Splice_Site 2035 Start_Codon_Del 5 Start_Codon_Ins 1 Start_Codon_SNP 47 Total 56482