Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.331 0.141 0.382 57.0 -9999.0 0.0 57.0 KIRREL -0.072 0.103 -9999.0 0.0 -0.529 3.0 3.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.332 0.141 -9999.0 0.0 -0.383 57.0 57.0 PLCG1 0.005 0.0 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.004 0.001 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.005 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.316 0.167 -9999.0 0.0 -0.354 59.0 59.0 ChemicalAbstracts:57-88-5 -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.319 0.17 -9999.0 0.0 -0.357 59.0 59.0 FYN -0.3 0.156 -9999.0 0.0 -0.336 59.0 59.0 mol:Ca2+ -0.313 0.165 -9999.0 0.0 -0.351 59.0 59.0 mol:DAG -0.314 0.166 -9999.0 0.0 -0.352 59.0 59.0 NPHS2 -0.223 0.236 -9999.0 0.0 -0.524 25.0 25.0 mol:IP3 -0.314 0.166 -9999.0 0.0 -0.352 59.0 59.0 regulation of endocytosis -0.275 0.15 -9999.0 0.0 -0.318 56.0 56.0 Nephrin/NEPH1/podocin/Cholesterol -0.316 0.166 -9999.0 0.0 -0.354 59.0 59.0 establishment of cell polarity -0.331 0.141 -9999.0 0.0 -0.382 57.0 57.0 Nephrin/NEPH1/podocin/NCK1-2 -0.29 0.157 -9999.0 0.0 -0.325 59.0 59.0 Nephrin/NEPH1/beta Arrestin2 -0.278 0.152 -9999.0 0.0 -0.322 56.0 56.0 NPHS1 -0.427 0.177 -9999.0 0.0 -0.501 56.0 56.0 Nephrin/NEPH1/podocin -0.301 0.158 -9999.0 0.0 -0.338 59.0 59.0 TJP1 0.005 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.005 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.005 0.0 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.316 0.167 -9999.0 0.0 -0.354 59.0 59.0 CD2AP 0.005 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 -0.316 0.167 -9999.0 0.0 -0.354 59.0 59.0 GRB2 0.005 0.0 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.286 0.154 -9999.0 0.0 -0.324 58.0 58.0 cytoskeleton organization -0.369 0.185 -9999.0 0.0 -0.413 59.0 59.0 Nephrin/NEPH1 -0.232 0.103 -9999.0 0.0 -0.268 57.0 57.0 Nephrin/NEPH1/ZO-1 -0.263 0.116 -9999.0 0.0 -0.304 57.0 57.0