Clinical Features Time to Death YEARS_TO_BIRTH PATHOLOGIC_STAGE PATHOLOGY_T_STAGE PATHOLOGY_N_STAGE PATHOLOGY_M_STAGE GENDER KARNOFSKY_PERFORMANCE_SCORE NUMBER_PACK_YEARS_SMOKED YEAR_OF_TOBACCO_SMOKING_ONSET RACE ETHNICITY nCNV (%) nWild-Type logrank test_P logrank test_Q Wilcoxon-test_P Wilcoxon-test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Wilcoxon-test_P Wilcoxon-test_Q Wilcoxon-test_P Wilcoxon-test_Q Wilcoxon-test_P Wilcoxon-test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q 1p gain 24 (5%) 504 0.0023696 0.042 0.16755 0.629 0.15217 0.59 0.26171 0.738 0.19079 0.668 0.38498 0.877 1 1 0.17696 0.65 NA NA NA NA 0.43081 0.916 1 1 1q gain 51 (10%) 477 0.050278 0.329 0.029676 0.228 0.057069 0.355 0.079809 0.431 0.40605 0.894 0.68153 1 0.54127 1 0.42636 0.914 NA NA NA NA 0.63375 1 0.72705 1 2p gain 77 (15%) 451 0.50466 0.987 0.13403 0.547 0.23625 0.713 0.42503 0.914 0.73948 1 0.23069 0.711 1 1 0.77563 1 0.54307 1 NA NA 0.40608 0.894 0.761 1 2q gain 79 (15%) 449 0.51872 1 0.21717 0.704 0.46187 0.937 0.54648 1 1 1 0.39249 0.884 0.52523 1 0.82921 1 0.54307 1 NA NA 0.33741 0.836 0.37411 0.877 3p gain 19 (4%) 509 0.10134 0.484 0.51564 1 0.14936 0.583 0.19442 0.669 0.038914 0.279 0.097766 0.476 0.33156 0.834 0.82092 1 NA NA NA NA 0.78424 1 1 1 3q gain 61 (12%) 467 0.19436 0.669 0.9046 1 0.00017 0.00757 5e-05 0.00307 0.0065462 0.0815 0.0073972 0.0899 0.67121 1 0.67055 1 NA NA NA NA 0.47922 0.962 1 1 4p gain 13 (2%) 515 0.14594 0.577 0.77421 1 0.38062 0.877 0.17065 0.636 0.47369 0.957 1 1 0.39571 0.887 NA NA NA NA NA NA 1 1 1 1 4q gain 13 (2%) 515 0.38276 0.877 0.77421 1 0.45619 0.936 0.67761 1 0.4341 0.918 0.70242 1 0.77889 1 NA NA NA NA NA NA 1 1 1 1 5p gain 193 (37%) 335 0.061645 0.375 0.00010815 0.00536 0.12873 0.542 0.17522 0.648 0.8028 1 1 1 0.014378 0.149 0.34254 0.836 0.91926 1 0.78076 1 0.03059 0.233 0.83321 1 5q gain 207 (39%) 321 0.06413 0.378 0.0003307 0.0108 0.37105 0.877 0.28737 0.777 0.61873 1 1 1 0.015764 0.157 0.46207 0.937 0.96679 1 0.78076 1 0.02741 0.214 0.83587 1 6p gain 11 (2%) 517 0.91613 1 0.79315 1 0.31154 0.804 0.23204 0.711 1 1 0.68643 1 0.34245 0.836 NA NA NA NA NA NA 1 1 1 1 6q gain 9 (2%) 519 0.74102 1 0.35877 0.867 0.21753 0.704 0.28287 0.771 1 1 1 1 0.16751 0.629 NA NA NA NA NA NA 1 1 1 1 7p gain 171 (32%) 357 0.98744 1 0.2282 0.711 0.059039 0.363 0.10389 0.487 0.30573 0.8 0.025487 0.207 0.003561 0.0531 0.98398 1 0.18195 0.653 0.063525 0.378 0.01887 0.168 0.65529 1 7q gain 172 (33%) 356 0.54918 1 0.26068 0.737 0.01426 0.149 0.051179 0.331 0.29629 0.792 0.002551 0.0427 0.0089729 0.104 0.66261 1 0.27527 0.761 0.063525 0.378 0.01852 0.168 0.27127 0.752 8p gain 31 (6%) 497 0.50282 0.987 0.17625 0.65 0.00085999 0.0203 0.00072999 0.0194 1 1 0.19399 0.669 0.56281 1 0.24146 0.716 NA NA NA NA 0.52407 1 0.38167 0.877 8q gain 62 (12%) 466 0.11251 0.506 0.045722 0.315 0.00341 0.0524 0.0050899 0.0677 0.43751 0.918 0.085489 0.45 0.091106 0.464 0.28578 0.775 0.79995 1 NA NA 0.73785 1 0.49648 0.982 9p gain 13 (2%) 515 0.17056 0.636 0.67402 1 0.90232 1 0.04687 0.32 1 1 0.23701 0.713 0.016645 0.16 NA NA NA NA NA NA 0.70916 1 0.55035 1 9q gain 12 (2%) 516 0.63272 1 0.33699 0.836 0.24109 0.716 0.00282 0.0462 1 1 1 1 0.12806 0.542 NA NA NA NA NA NA 1 1 0.55035 1 10p gain 17 (3%) 511 0.72366 1 0.094955 0.472 0.17146 0.637 0.10173 0.484 0.095052 0.472 0.73901 1 0.79779 1 0.89972 1 NA NA NA NA 0.41574 0.903 1 1 10q gain 12 (2%) 516 0.72998 1 0.015156 0.154 0.84703 1 0.87977 1 0.24594 0.716 1 1 0.36371 0.873 0.57847 1 NA NA NA NA 0.48616 0.968 1 1 11p gain 31 (6%) 497 0.56278 1 0.98642 1 0.02757 0.214 0.01258 0.138 1 1 0.11563 0.506 0.84717 1 0.28818 0.777 NA NA NA NA 0.73127 1 1 1 11q gain 29 (5%) 499 0.21457 0.701 0.94647 1 0.16288 0.619 0.084089 0.449 1 1 0.42041 0.909 1 1 NA NA NA NA NA NA 0.84846 1 1 1 12p gain 121 (23%) 407 0.0060307 0.0761 0.18548 0.661 0.00028 0.00984 0.00144 0.0283 0.047938 0.32 0.019331 0.168 0.38829 0.882 0.018021 0.166 0.31076 0.804 NA NA 0.10857 0.499 0.22463 0.711 12q gain 122 (23%) 406 0.0091772 0.105 0.33433 0.835 0.00018 0.00757 0.00079999 0.0202 0.047938 0.32 0.019907 0.172 0.33408 0.835 0.018021 0.166 0.31076 0.804 NA NA 0.11193 0.506 0.22496 0.711 13q gain 22 (4%) 506 0.12636 0.541 0.25386 0.73 0.12863 0.542 0.20601 0.692 1 1 0.367 0.877 0.25703 0.733 NA NA NA NA NA NA 0.097669 0.476 0.089971 0.464 14q gain 16 (3%) 512 0.13051 0.542 0.47276 0.957 0.22615 0.711 0.0053099 0.0697 1 1 0.29538 0.792 0.79638 1 NA NA NA NA NA NA 1 1 1 1 15q gain 26 (5%) 502 0.53776 1 0.45056 0.929 0.44808 0.929 0.37123 0.877 0.19079 0.668 0.58245 1 0.67795 1 0.053069 0.341 NA NA NA NA 0.56479 1 1 1 16p gain 107 (20%) 421 0.37089 0.877 0.24507 0.716 0.15718 0.607 0.071069 0.407 0.21028 0.694 0.6482 1 0.65226 1 0.66873 1 0.064066 0.378 NA NA 0.23846 0.715 1 1 16q gain 99 (19%) 429 0.24662 0.716 0.33756 0.836 0.22246 0.711 0.04851 0.32 0.20761 0.693 1 1 1 1 0.58305 1 0.064066 0.378 NA NA 0.41993 0.909 0.78651 1 17p gain 26 (5%) 502 0.7656 1 0.55653 1 0.29682 0.792 0.8245 1 0.19079 0.668 0.021348 0.182 1 1 0.67884 1 NA NA NA NA 0.02662 0.213 0.61214 1 17q gain 33 (6%) 495 0.44066 0.919 0.3408 0.836 0.68727 1 0.65815 1 0.29603 0.792 0.20173 0.68 0.70872 1 0.55891 1 0.38892 0.882 NA NA 0.061729 0.375 0.38296 0.877 18p gain 25 (5%) 503 0.06875 0.4 0.80437 1 0.92881 1 0.87181 1 0.60745 1 0.40054 0.891 0.090714 0.464 NA NA NA NA NA NA 0.66865 1 0.33159 0.834 18q gain 25 (5%) 503 0.13224 0.544 0.617 1 0.83262 1 0.76523 1 0.57739 1 0.40054 0.891 0.090714 0.464 NA NA NA NA NA NA 0.66702 1 0.33159 0.834 19p gain 51 (10%) 477 0.77628 1 0.67585 1 0.00302 0.0472 0.013 0.141 0.23227 0.711 0.0078085 0.0937 0.22043 0.709 0.49403 0.98 NA NA NA NA 0.073889 0.411 0.72705 1 19q gain 57 (11%) 471 0.81401 1 0.39151 0.884 0.00086999 0.0203 0.00494 0.0671 0.41565 0.903 0.0035373 0.0531 0.24205 0.716 0.49403 0.98 NA NA NA NA 0.03128 0.235 1 1 20p gain 112 (21%) 416 0.14078 0.564 0.23315 0.711 3e-05 0.00204 9.9999e-06 0.00141 0.37526 0.877 0.016733 0.16 0.00035011 0.0108 0.96474 1 0.49811 0.982 NA NA 0.32842 0.833 0.44155 0.919 20q gain 115 (22%) 413 0.10381 0.487 0.078741 0.431 2e-05 0.00179 9.9999e-06 0.00141 0.22464 0.711 0.018794 0.168 0.0019901 0.0363 0.96474 1 0.49811 0.982 NA NA 0.31569 0.811 0.31927 0.815 21q gain 50 (9%) 478 0.69122 1 0.11614 0.506 0.22632 0.711 0.11311 0.506 1 1 0.53333 1 0.43919 0.919 0.11249 0.506 0.47799 0.962 NA NA 0.21982 0.709 0.71881 1 22q gain 40 (8%) 488 0.36387 0.873 0.56285 1 0.70376 1 0.088199 0.462 1 1 0.82026 1 0.30498 0.8 0.42223 0.911 NA NA NA NA 0.21288 0.701 1 1 xp gain 32 (6%) 496 0.52967 1 0.55751 1 0.02392 0.198 0.095869 0.474 1 1 0.036873 0.269 0.85052 1 0.94259 1 NA NA NA NA 0.10776 0.499 0.38296 0.877 xq gain 31 (6%) 497 0.87694 1 0.78062 1 0.053749 0.342 0.11559 0.506 1 1 0.027381 0.214 0.7045 1 0.5581 1 NA NA NA NA 0.53398 1 0.38296 0.877 1p loss 57 (11%) 471 0.53563 1 0.13066 0.542 0.4359 0.918 0.0152 0.154 1 1 0.43075 0.916 0.38079 0.877 0.71986 1 NA NA NA NA 0.44957 0.929 0.20927 0.693 1q loss 36 (7%) 492 0.83193 1 0.65494 1 0.84349 1 0.075679 0.418 1 1 0.33841 0.836 0.59059 1 0.75958 1 NA NA NA NA 0.37393 0.877 0.45042 0.929 2p loss 14 (3%) 514 0.8153 1 0.83855 1 0.42992 0.916 0.13871 0.561 1 1 0.70745 1 0.77894 1 NA NA NA NA NA NA 0.055729 0.35 1 1 2q loss 14 (3%) 514 0.80373 1 0.81429 1 0.53909 1 0.22116 0.709 1 1 0.70745 1 0.77894 1 NA NA NA NA NA NA 0.17877 0.651 1 1 3p loss 380 (72%) 148 0.60554 1 0.81473 1 0.03918 0.279 0.02713 0.214 0.59293 1 0.10009 0.48 0.011354 0.127 0.64279 1 0.52246 1 0.45797 0.936 0.18308 0.655 0.65474 1 3q loss 99 (19%) 429 0.99341 1 0.013524 0.145 0.48187 0.966 0.23324 0.711 0.4848 0.968 0.87605 1 0.00010899 0.00536 0.079094 0.431 NA NA NA NA 0.69382 1 0.7832 1 4p loss 72 (14%) 456 5.5494e-05 0.00321 0.74282 1 2e-04 0.00757 0.00025 0.00911 0.71839 1 0.021626 0.182 0.89524 1 0.87361 1 NA NA NA NA 0.04488 0.313 0.39895 0.891 4q loss 65 (12%) 463 4.2421e-06 0.00141 0.82834 1 3e-05 0.00204 2e-05 0.00179 0.43751 0.918 0.0029309 0.0471 0.27043 0.752 0.82683 1 NA NA NA NA 0.02164 0.182 0.55006 1 5p loss 7 (1%) 521 0.023186 0.193 0.25177 0.727 0.00168 0.0312 2e-04 0.00757 1 1 0.081587 0.439 0.25576 0.733 NA NA NA NA NA NA 1 1 1 1 5q loss 6 (1%) 522 0.066373 0.389 0.14977 0.583 0.0055699 0.0721 0.00037 0.011 1 1 0.24016 0.716 0.67162 1 NA NA NA NA NA NA 1 1 1 1 6p loss 100 (19%) 428 0.37557 0.877 0.27068 0.752 0.0481 0.32 0.01695 0.16 0.015588 0.157 0.27926 0.765 0.0011779 0.0244 0.114 0.506 0.50999 0.996 0.64274 1 0.03624 0.266 1 1 6q loss 128 (24%) 400 0.43104 0.916 0.66581 1 0.30425 0.8 0.18156 0.653 0.0036258 0.0532 0.66875 1 0.071656 0.408 0.5011 0.986 0.033704 0.249 0.64274 1 0.071069 0.407 0.47605 0.96 7p loss 3 (1%) 525 0.030725 0.233 0.69523 1 0.073799 0.411 0.01755 0.164 0.13112 0.542 1 1 0.55612 1 NA NA NA NA NA NA 0.32552 0.828 1 1 7q loss 4 (1%) 524 0.26541 0.746 0.71192 1 0.04516 0.313 0.01599 0.157 0.13112 0.542 1 1 0.30219 0.797 NA NA NA NA NA NA 0.40788 0.895 0.19391 0.669 8p loss 137 (26%) 391 0.17958 0.651 0.67413 1 0.31987 0.815 0.18974 0.668 1 1 0.26684 0.748 0.038857 0.279 0.84103 1 0.96398 1 0.45797 0.936 0.12964 0.542 0.055893 0.35 8q loss 64 (12%) 464 0.45853 0.936 0.80453 1 0.62904 1 0.24447 0.716 1 1 1 1 0.012511 0.138 0.65311 1 NA NA NA NA 0.2295 0.711 0.050432 0.329 9p loss 149 (28%) 379 1.8864e-05 0.00179 0.057341 0.355 2e-05 0.00179 5.9999e-05 0.00328 0.085377 0.45 0.0016012 0.0303 0.00088656 0.0203 0.67284 1 1 1 0.87234 1 0.1354 0.551 0.65544 1 9q loss 150 (28%) 378 0.00029531 0.01 0.040368 0.286 9.9999e-06 0.00141 9.9999e-06 0.00141 0.09412 0.472 0.0041083 0.0586 0.00086005 0.0203 0.4374 0.918 1 1 0.87234 1 0.12418 0.534 0.8227 1 10p loss 67 (13%) 461 0.36343 0.873 0.35785 0.867 0.073429 0.411 0.0090199 0.104 0.236 0.713 0.58284 1 0.33986 0.836 0.14471 0.574 NA NA NA NA 0.59257 1 0.20927 0.693 10q loss 89 (17%) 439 0.51873 1 0.5363 1 0.099249 0.48 0.00242 0.042 0.4848 0.968 0.62659 1 0.11478 0.506 0.18749 0.666 NA NA NA NA 0.28541 0.775 0.27762 0.765 11p loss 18 (3%) 510 0.0038895 0.0563 0.0538 0.342 0.27904 0.765 0.40279 0.891 0.14093 0.564 0.50451 0.987 1 1 0.78907 1 NA NA NA NA 1 1 1 1 11q loss 23 (4%) 505 0.002558 0.0427 0.0059043 0.0755 0.45278 0.932 0.51558 1 0.21667 0.704 0.38498 0.877 0.37983 0.877 0.37772 0.877 NA NA NA NA 0.64385 1 1 1 12p loss 4 (1%) 524 0.25847 0.735 0.68993 1 0.77219 1 1 1 1 1 1 1 0.62009 1 NA NA NA NA NA NA 0.41013 0.897 1 1 12q loss 4 (1%) 524 0.82923 1 0.31222 0.804 0.15905 0.608 0.40829 0.895 1 1 1 1 1 1 NA NA NA NA NA NA 1 1 1 1 13q loss 71 (13%) 457 0.0015711 0.0303 0.92788 1 0.00019 0.00757 9.9999e-06 0.00141 0.30047 0.795 0.033316 0.248 0.42521 0.914 0.87361 1 NA NA NA NA 0.20875 0.693 0.22754 0.711 14q loss 216 (41%) 312 0.000776 0.0201 0.25666 0.733 9.9999e-06 0.00141 3e-05 0.00204 0.00072406 0.0194 0.0011057 0.0237 0.026646 0.213 0.044119 0.31 0.20118 0.68 0.073025 0.411 0.0192 0.168 0.68602 1 15q loss 36 (7%) 492 0.00093404 0.0204 0.96471 1 0.00126 0.0253 0.00052999 0.0153 1 1 0.014226 0.149 0.10397 0.487 0.59938 1 NA NA NA NA 0.1789 0.651 0.38468 0.877 16p loss 10 (2%) 518 0.090999 0.464 0.65204 1 0.39526 0.887 0.01691 0.16 0.34636 0.844 1 1 1 1 NA NA NA NA NA NA 0.40097 0.891 1 1 16q loss 16 (3%) 512 0.13903 0.561 0.33213 0.834 0.41184 0.899 0.00498 0.0671 0.4341 0.918 1 1 0.79638 1 NA NA NA NA NA NA 0.16625 0.629 1 1 17p loss 46 (9%) 482 0.34225 0.836 0.30014 0.795 0.1442 0.574 0.13409 0.547 0.37479 0.877 0.047395 0.32 0.19735 0.67 0.29865 0.794 NA NA NA NA 1 1 0.71264 1 17q loss 28 (5%) 500 0.44144 0.919 0.7868 1 0.30731 0.802 0.25963 0.736 1 1 0.17989 0.651 0.31088 0.804 NA NA NA NA NA NA 0.84121 1 1 1 18p loss 93 (18%) 435 0.00093047 0.0204 0.092677 0.468 0.00034 0.0108 2e-04 0.00757 1 1 0.079678 0.431 0.23412 0.711 0.91054 1 NA NA NA NA 0.23336 0.711 0.097785 0.476 18q loss 95 (18%) 433 0.0045982 0.0637 0.11334 0.506 0.0089699 0.104 0.00417 0.0586 1 1 0.11279 0.506 0.1934 0.669 0.77011 1 NA NA NA NA 0.2145 0.701 0.28021 0.766 19p loss 11 (2%) 517 3.1072e-05 0.00204 0.09268 0.468 0.02541 0.207 0.00059999 0.0169 1 1 0.39125 0.884 0.75375 1 NA NA NA NA NA NA 0.12134 0.524 1 1 19q loss 4 (1%) 524 0.0024351 0.042 0.84447 1 0.19512 0.669 0.00297 0.0471 1 1 0.11838 0.513 1 1 NA NA NA NA NA NA 1 1 1 1 20p loss 8 (2%) 520 0.73181 1 0.70111 1 0.79077 1 0.61201 1 1 1 0.36609 0.876 1 1 NA NA NA NA NA NA 0.15805 0.607 0.2501 0.724 20q loss 3 (1%) 525 0.87344 1 0.11489 0.506 0.23402 0.711 0.10835 0.499 NA NA 0.40215 0.891 1 1 NA NA NA NA NA NA 1 1 0.069149 0.4 21q loss 55 (10%) 473 0.72599 1 0.72314 1 0.10659 0.497 0.00119 0.0244 0.084408 0.449 1 1 0.46085 0.937 0.84207 1 NA NA NA NA 0.58141 1 1 1 22q loss 39 (7%) 489 0.0072549 0.0892 0.24236 0.716 0.01897 0.168 0.15938 0.608 1 1 0.10007 0.48 0.86262 1 0.94811 1 NA NA NA NA 1 1 0.0095931 0.109 xp loss 46 (9%) 482 0.31739 0.813 0.97654 1 0.90137 1 0.54098 1 0.24294 0.716 0.82587 1 0.19735 0.67 0.35856 0.867 NA NA NA NA 0.80866 1 0.14923 0.583 xq loss 46 (9%) 482 0.24419 0.716 0.60653 1 0.9008 1 0.53844 1 0.26945 0.752 1 1 0.19735 0.67 0.69581 1 NA NA NA NA 0.58605 1 0.15002 0.583