Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.252 0.154 0.339 392.0 -9999.0 0.0 392.0 KIRREL -0.058 0.061 -9999.0 0.0 -0.461 7.0 7.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.252 0.155 -9999.0 0.0 -0.339 392.0 392.0 PLCG1 0.019 0.004 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.02 0.003 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.018 0.006 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.259 0.175 -9999.0 0.0 -0.336 417.0 417.0 ChemicalAbstracts:57-88-5 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.261 0.181 -9999.0 0.0 -0.354 387.0 387.0 FYN -0.253 0.15 0.262 1.0 -0.316 417.0 418.0 mol:Ca2+ -0.252 0.176 -9999.0 0.0 -0.333 409.0 409.0 mol:DAG -0.253 0.177 -9999.0 0.0 -0.334 409.0 409.0 NPHS2 -0.23 0.209 -9999.0 0.0 -0.456 240.0 240.0 mol:IP3 -0.253 0.177 -9999.0 0.0 -0.334 409.0 409.0 regulation of endocytosis -0.235 0.155 -9999.0 0.0 -0.303 417.0 417.0 Nephrin/NEPH1/podocin/Cholesterol -0.256 0.171 -9999.0 0.0 -0.33 417.0 417.0 establishment of cell polarity -0.252 0.154 -9999.0 0.0 -0.339 392.0 392.0 Nephrin/NEPH1/podocin/NCK1-2 -0.236 0.169 -9999.0 0.0 -0.313 410.0 410.0 Nephrin/NEPH1/beta Arrestin2 -0.238 0.158 -9999.0 0.0 -0.306 417.0 417.0 NPHS1 -0.343 0.18 -9999.0 0.0 -0.44 404.0 404.0 Nephrin/NEPH1/podocin -0.247 0.163 -9999.0 0.0 -0.318 417.0 417.0 TJP1 0.02 0.002 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.018 0.02 -9999.0 0.0 -0.417 1.0 1.0 NCK2 0.019 0.004 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.254 0.178 -9999.0 0.0 -0.336 409.0 409.0 CD2AP 0.019 0.004 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 -0.256 0.177 -9999.0 0.0 -0.335 415.0 415.0 GRB2 0.02 0.003 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.246 0.148 0.27 1.0 -0.308 415.0 416.0 cytoskeleton organization -0.306 0.2 -9999.0 0.0 -0.411 383.0 383.0 Nephrin/NEPH1 -0.173 0.109 -9999.0 0.0 -0.234 392.0 392.0 Nephrin/NEPH1/ZO-1 -0.2 0.131 -9999.0 0.0 -0.274 390.0 390.0