Signaling events mediated by the Hedgehog family
Entity	Mean	Std Dev	Mean of Up Perturbations	Number of Up Perturbations	Mean of Down Perturbations	Number of Down Perturbations	Number of Total Perturbations
TGFB2	0.078	0.112	0.323	1.0	-0.44	1.0	2.0
IHH	0.021	0.131	0.212	5.0	-0.419	40.0	45.0
SHH Np/Cholesterol/GAS1	-0.029	0.051	0.12	1.0	-0.234	29.0	30.0
LRPAP1	0.02	0.003	-9999.0	0.0	-9999.0	0.0	0.0
dorsoventral neural tube patterning	0.029	0.05	0.232	29.0	-0.119	1.0	30.0
SMO/beta Arrestin2	0.05	0.117	0.294	1.0	-0.334	13.0	14.0
SMO	0.033	0.111	-9999.0	0.0	-0.345	14.0	14.0
AKT1	0.02	0.098	-9999.0	0.0	-0.412	14.0	14.0
ARRB2	0.02	0.003	-9999.0	0.0	-9999.0	0.0	0.0
BOC	0.019	0.006	-9999.0	0.0	-9999.0	0.0	0.0
ADRBK1	0.02	0.002	-9999.0	0.0	-9999.0	0.0	0.0
heart looping	0.032	0.11	-9999.0	0.0	-0.341	14.0	14.0
STIL	0.036	0.095	0.245	36.0	-0.289	2.0	38.0
DHH N/PTCH2	0.027	0.054	-9999.0	0.0	-0.298	11.0	11.0
DHH N/PTCH1	0.055	0.1	-9999.0	0.0	-0.267	19.0	19.0
PIK3CA	0.018	0.02	-9999.0	0.0	-0.417	1.0	1.0
DHH	0.01	0.065	-9999.0	0.0	-0.417	12.0	12.0
PTHLH	0.094	0.141	0.336	7.0	-0.525	1.0	8.0
determination of left/right symmetry	0.032	0.11	-9999.0	0.0	-0.341	14.0	14.0
PIK3R1	0.017	0.02	-9999.0	0.0	-0.417	1.0	1.0
skeletal system development	0.094	0.141	0.335	7.0	-0.521	1.0	8.0
IHH N/Hhip	-0.049	0.175	0.22	5.0	-0.326	142.0	147.0
DHH N/Hhip	-0.048	0.145	-9999.0	0.0	-0.306	123.0	123.0
mol:Cholesterol	0.0	0.0	-9999.0	0.0	-9999.0	0.0	0.0
heart development	0.032	0.11	-9999.0	0.0	-0.341	14.0	14.0
pancreas development	-0.074	0.184	0.188	10.0	-0.416	116.0	126.0
HHAT	0.019	0.004	-9999.0	0.0	-9999.0	0.0	0.0
PI3K	0.025	0.022	-9999.0	0.0	-0.301	2.0	2.0
EntrezGene:84976	0.0	0.0	-9999.0	0.0	-9999.0	0.0	0.0
GAS1	-0.002	0.095	0.188	1.0	-0.417	26.0	27.0
somite specification	0.032	0.11	-9999.0	0.0	-0.341	14.0	14.0
SHH Np/Cholesterol/PTCH1	0.029	0.086	-9999.0	0.0	-0.273	4.0	4.0
SHH Np/Cholesterol/PTCH2	-0.015	0.041	0.121	21.0	-0.228	10.0	31.0
SHH Np/Cholesterol/Megalin	-0.032	0.061	0.121	1.0	-0.252	35.0	36.0
SHH	-0.021	0.036	-9999.0	0.0	-0.301	8.0	8.0
catabolic process	0.06	0.102	-9999.0	0.0	-0.284	14.0	14.0
SMO/Vitamin D3	0.037	0.11	0.309	10.0	-0.36	4.0	14.0
SHH Np/Cholesterol/Hhip	-0.061	0.095	0.121	7.0	-0.24	109.0	116.0
LRP2	-0.01	0.111	0.188	1.0	-0.417	36.0	37.0
receptor-mediated endocytosis	0.01	0.115	0.248	8.0	-0.419	13.0	21.0
SHH Np/Cholesterol/BOC	-0.02	0.03	-9999.0	0.0	-0.229	10.0	10.0
SHH Np/Cholesterol/CDO	-0.007	0.053	0.124	52.0	-0.231	10.0	62.0
mesenchymal cell differentiation	0.061	0.094	0.239	109.0	-0.12	7.0	116.0
mol:Vitamin D3	0.061	0.115	0.299	38.0	-0.287	3.0	41.0
IHH N/PTCH2	0.034	0.087	0.19	17.0	-0.246	39.0	56.0
CDON	0.039	0.053	0.188	59.0	-9999.0	0.0	59.0
IHH N/PTCH1	0.078	0.112	0.256	4.0	-0.286	14.0	18.0
Megalin/LRPAP1	0.007	0.081	-9999.0	0.0	-0.3	34.0	34.0
PTCH2	0.027	0.036	0.188	25.0	-9999.0	0.0	25.0
SHH Np/Cholesterol	-0.016	0.03	-9999.0	0.0	-0.225	10.0	10.0
PTCH1	0.061	0.103	-9999.0	0.0	-0.284	14.0	14.0
HHIP	-0.074	0.184	0.188	10.0	-0.417	116.0	126.0